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Apr 16

Episode 52: The THYROID Episode, With Elle Russ! Self-Diagnosing Thyroid Problems, Lab Markers, Hypothyroid Signs, T4 Medication, Natural Desiccated Thyroid (NDT), Feeling Bad Despite “Normal” Levels, IF’s Effects On The Thyroid & Adrenals, The Role Of Stress, Mindsets, Doing LESS To Gain More, Loving Your Body

Adrenal Fatigue , Diet Mindsets , Fasting Approaches , Intermittent Fasting

Welcome to Episode 52 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Gin Stephens, author of Delay, Don't Deny: Living An Intermittent Fasting Lifestyle

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

About ELLE RUSS

Elle Russ is a writer and host of the popular Primal Blueprint Podcast. She is the leading voice of thyroid health in the fast-growing Paleo, Primal, and Ancestral Health Movements. Originally from downtown Chicago, Elle lives and plays in Malibu, CA. You can learn more about her at ElleRuss.com

Elle wrote The Paleo Thyroid Solution after consulting with over two dozen endocrinologists, internal medicine specialists, and general practice MDs...but her thyroid condition was only getting worse - and nothing from doctors resembled a solution, or even hope. Exasperated and desperate, Elle took control of her own health and resolved two severe bouts of hypothyroidism on her own – including an acute Reverse T3 problem. Through a devoted paleo/primal lifestyle, intensive personal experimentation, and a radically modified approach to thyroid hormone replacement therapy…Elle went from fat, foggy, and fatigued – to fit, focused, and full of life!

GET ELLE'S FREE THYROID GUIDE!!

Follow Elle On Instagram & Twitter!  

Elle's Story & The Problem With Diagnosing Thyroid Problems Today

Self-Diagnosing Thyroid Problems With Temps

How The Thyroid Works

What Lab Markers You Need To Get Tested

Conventional T4 Medications Vs Natural Desiccated Thyroid

Listener Q&A: Stephanie  - My doctor is concerned about IF affecting adrenally, thyroid and hormone levels?

Listener Q&A: Sallie  - Does IF put too much stress on the adrenals and the whole adrenal/thyroid complex?

Listener Q&A: Alessandra  - Is an IF lifestyle okay for someone hypothyroidism? 

The Importance Of Not Going Too Hard

The Significance of Cortisol, Stress And Being Kind To Your Body

Listener Q&A:  - The Significance of Stress, Finding the Root Of The Problem, Doing Less Rather Than More, & Loving Your Your Body

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

REFERENCES

LINKS

More on Melanie: MelanieAvalon.com  

More on Gin: GinStephens.com

BUY Delay Don't Deny: Living An Intermittent Fasting Lifestyle and Feast Without Fear: Food and the Delay, Don't Deny Lifestyle

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Dec 25

Episode 297: Ashwagandha, Diabetes, Berberine, Creatine, Long Term Calorie Restriction, Women In Podcasting, Echo Chambers, The Four Tendencies, And More!

Intermittent Fasting

Welcome to Episode 297 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

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To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX:  For A Limited Time Go To butcherbox.com/ifpodcast And Get The New Year Bundle For Free Plus $10 Off When You Sign Up Today. That’s A 14 Oz Pork Tenderloin, 2 Lbs Of Ground Turkey, And 4 Top Sirloin Steaks Free In Your First Box!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

The Melanie Avalon Biohacking Podcast Episode #177 - A.J. Jacobs

The Melanie Avalon Biohacking Podcast Episode #175 - Seth Stephens-Davidowitz

ATHLETIC GREENS: Get A FREE 1 Year Supply Of Immune-Supporting Vitamin D AND 5 FREE Travel Packs With Your First Purchase At athleticgreens.com/ifpodcast.

Listener Q&A: Cici - ashwagandha & diabetes

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Listener Q&A: Niki - Creatine

BON CHARGE: For a limited time Go To boncharge.com And Use Coupon Code IFPODCAST To Save 25% through January 2nd!

Listener Q&A: Alex - Hi Ladies!

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 297 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: A 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine if it's that time, and get ready for The Intermittent Fasting Podcast.

Hi friends. I'm about to tell you how you can get a 14-ounce heritage-breed pork tenderloin 2 pounds of sustainably raised ground turkey and four grass-fed top sirloin steaks all for free plus $10 off. Yes, all of that incredible meat plus $10 off all for free. We are a bit obsessed with the company called ButcherBox, which is always in season. Some of my favorite meals that I had throughout the holiday season were fantastic meat and seafood from ButcherBox. Now, with the new year, it is time to celebrate with only the very best of the best when it comes to meat and seafood that you put in your body as well as meat and seafood that helps support our planet and the environment. 

They make it so so easy to get high-quality, humanely raised meat that you can trust. They deliver 100% grass-fed, grass-finished beef, free-range organic chicken, heritage-breed pork that's really hard to find, by the way, and wild-caught sustainable and responsible seafood shipped directly to your door. When you become a member, you're joining a community focused on doing what's better for everyone. That includes caring about the lives of animals, the livelihoods of farmers, treating our planet with respect and enjoying deliciously better meals together. I did so much research on ButcherBox. You can actually check out my blog post all about it at melanieavalon.com/butcherbox. All of their beef is 100% grass-fed and grass-finished, they work personally with all the farmers to truly support the regenerative agriculture system. I also did an interview with Robb Wolf on my show, The Melanie Avalon Biohacking Podcast, all about the massive importance of supporting regenerative agriculture for the sustainability of not only ourselves but the planet. This is so important to me. I'll put a link to that in the show notes.

The value is incredible. The average cost is actually less than $6 per meal. And it's so easy. Everything ships directly to your door and it is so delicious. I love carpaccio for example, the ButcherBox steaks are incredible for that. That's how you know it's good steak when you can eat it rare like that. ButcherBox has an incredible offer for our audience. You can get the New Year bundle for free plus $10 off when you sign up today. That's a 14-ounce heritage-breed pork tenderloin, 2 pounds of sustainably raised ground turkey, and four grass-fed top sirloin steaks, all for free in your first box. Sign up at butcherbox.com/if podcast and use code IFPODCAST to claim this offer. Again, to get a 14-ounce heritage-breed pork tenderloin, 2 pounds of sustainably raised ground turkey, and four grass-fed top sirloin steaks all for free plus $10 off. Sign up at butcherbox.com/ifpodcast and use code IFPODCAST to claim this offer. We'll put all this information in the show notes.

And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting, it's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things, like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup may be playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That's because ladies when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years.

Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means when you put on some conventional lipstick, 30 years later maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life. And their makeup is amazing. Check out my Instagram to see what it looks like. Tina Fey, even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook Group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well.

And lastly, if you're thinking of making Clean Beauty and Safe Skincare a part of your future we have, we definitely recommend becoming a Band of Beauty member. It's sort of Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now back to the show.

Hi, everybody, and welcome. This is episode number 297 of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hey, Melanie. How are you? 

Melanie Avalon: I'm good. I have a question for you. Have you done, is it, BBL, for laser? 

Cynthia Thurlow: Broadband light?

Melanie Avalon: Yeah.

Cynthia Thurlow: Yes. I do that in conjunction with Profractional once a year.

Melanie Avalon: I'm about to do it right after this.

Cynthia Thurlow: Well, did they tell you that it's not painless? I don't share that with you to frighten you. No one told me that. The first time I had just plain BBL, it's like snapping a rubber band against your skin.

Melanie Avalon: Oh, awesome.

Cynthia Thurlow: I'm sure they'll probably give you something topical, but if they don't ask for It.

Melanie Avalon: Oh, should I put numbing cream on my face? I have it.

Cynthia Thurlow: I would bring it with you and just double-checked. They may have something that they want you to use.

Melanie Avalon: Is it okay if you have cream on your face?

Cynthia Thurlow: They're probably going to clean it. I would ask them what their protocol is?

Melanie Avalon: Probably should have thought about this a little bit earlier.

Cynthia Thurlow: Because, I can tell you BBL is not painless, but with numbing cream it is tolerable.

Melanie Avalon: Okay. I might put on some numbing cream while we're talking, so it can be like soaking in because I think it has to soak in for a little bit because I do laser hair removal and always use the numbing cream for all of that.

Cynthia Thurlow: Did they give you lidocaine in a jar? 

Melanie Avalon: Yeah, I have that and then I have, there's one I order on Amazon that I like as well.

Cynthia Thurlow: Okay. It's probably not as strong like when I get Profractional and BBL done on my face, it's like the most you can legally prescribe. It works very effectively. Like my face will stay numb for 2 hours.

Melanie Avalon: Wow. Okay, I might grab some. Second question is because I'm glad you've had it, they said I'll be fine because I am recording with Ben Azadi tomorrow.

Cynthia Thurlow: Oh, you'll be fine. Yeah. If you have melasma or if you have any brown discoloration on your face, it'll make it darker, but it's not like you can't function. It'll be darker and then it all flakes off and go away.

Melanie Avalon: Yeah, that's what people said. They said it rises to the surface and then falls off.

Cynthia Thurlow: Yeah. It's like if you have an exaggerated freckle and then it goes away.

Melanie Avalon: And then it goes away. I'm very excited.

Cynthia Thurlow: Yeah, it works very effectively and I think most people don't even realize how much brown pigment they have in their face until they get it done and then they're like, Holy cow.

Melanie Avalon: It's pulling out the pigment from your face, sort of?

Cynthia Thurlow: The laser itself helps to break up the pigmentation. Like you can have red areas in your face and you can have discoloration like brown areas. Especially for women that have been on oral contraceptives or just have had a lot of sun exposure, they can have melasma and pigmentation on their face that most women don't want to have, so it's an easy way to help address it.

Melanie Avalon: Awesome. I've heard really wonderful things about it.

Cynthia Thurlow: Yeah. I go once a year and I always say, like, I have a love-hate relationship. I love the way it looks once I've healed, but I don't love it at the time. It's quick, so it'll be over before you know it.

Melanie Avalon: Well, I'll start while we're talking, I'll be rubbing some numbing cream on my face. What's new with you?

Cynthia Thurlow: Not a whole lot. Gearing up for the holidays and excited to not be traveling. Last Christmas we went away, we had a wonderful vacation and my kids kept saying, it's just weird for it to be warm [laughs] in Christmas. This year they wanted to stay home and so we are staying home and my mom and stepfather are coming to visit. Be a little bit of high [unintelligible [00:11:15] my mom is here but she means well. You know moms can be.

Melanie Avalon: Yeah. Holiday, family dynamics.

Cynthia Thurlow: Yes. How about you?

Melanie Avalon: Well, actually to that, my dad actually is having surgery, and it's a pretty intense surgery, so I'm sure it's going to be fine. It's really made me want to make sure I do a lot of stuff. I mean, it's going to be fine. We planned a lot of really fun things to do. Like, this weekend I'm going over we're going to just have a game night, and then we're going to do an escape room that's King Tut themed. Have you done escape rooms?

Cynthia Thurlow: I have not yet. I think when that started to become really popular, it was like preceding the pandemic and then the pandemic happened and we never did it.

Melanie Avalon: They're so fun and when you do them, you just realize, I feel like they're really good for your brain, your body because you're like moving all around. They're very immersive. Yeah, they're super fun. I've only done two. This will be my third one, but I would love to do them more. Actually it's funny, I interviewed A.J. Jacobs. Do you know him?

Cynthia Thurlow: I do not.

Melanie Avalon: He's so funny. It's been one of my favorite interviews to date. I was dying laughing. He wrote a lot of books. He's like a four times New York Times bestseller. He just does random stuff. Like his most well-known book. He just read the entire encyclopedia and talks about what he learned from it. The puzzle book, though, was about puzzles. In any case, he just has a section on escape rooms and this never occurred to me. Apparently, there're a lot of cliche guests that show up at escape rooms and one of the cliches will be the guy that will ask a girl on a first date and take her to the escape room, but he's done it multiple times, so he knows all the answers, and then he acts like he doesn't.

Cynthia Thurlow: Okay.

Melanie Avalon: Sneaky.

Cynthia Thurlow: Yes.

Melanie Avalon: All the escape rooms, but anything else new in your life?

Cynthia Thurlow: No, just gearing up for 2023 and trying to survive day to day with teenagers that are at times snarky and at times funny and trying to remind myself that those pleasant little cute kiddos are buried deep within them. I have moments where I'm just like, "Oh, my goodness." We just got back from visiting three colleges last week, and one with a big stand out for my son, who I think wants to study engineering. And it's hard to believe. It's like I blink. I remember when he was born and it's like, how is it possible that we're looking at colleges? This is like a top 20 engineering program, and so it's like one out of eight kids get in. It's really intense. Having to explain to him, you got to work your butt off. This is not half-assing anything. And he's got, like, four AP classes. He's got a pretty intense year, so we're just trying to help him head in the right direction, and hopefully, he'll have a couple of reaches and a couple of safety schools and then have some others that are pretty much guaranteed. But we're fortunate we're in a state where there are a lot of, I would say there's probably three or four really good state schools that a lot of people come to from out of state, so we're fortunate. Do you remember those applying to college years?

Melanie Avalon: I graduated early, so I applied when I was a sophomore in high school, so I didn't even go through the college application process.

Cynthia Thurlow: Oh, my gosh.

Melanie Avalon: Yeah, I applied to USC. They have an early entrance program. I found out, I guess early junior year and then I left after that year.

Cynthia Thurlow: That's interesting because they have two early decision options now. This is how it is in each school we looked at and one is binding and one is not. Essentially, they take the university he wants to go to. That's his first choice. They take 350 students, early decision.

Melanie Avalon: So, it that where you skip senior year of high school?

Cynthia Thurlow: No, he's going to need to go his senior year.

Melanie Avalon: Oh, it's just like making the decision earlier.

Cynthia Thurlow: Yeah. Well, he would be if he does an early decision and gets accepted, he knows November 1 where he's going to go the following year, but that's binding.

Melanie Avalon: Okay. Yeah. I got to live vicariously through my other friends and then also, like, my siblings. And it was fun. They actually let me in my high school, they let me go on the senior trip even though I was gone. I had been in college a year and then I went on my senior trip with my high school friends and they were just graduating.

Cynthia Thurlow: What was that like to go to college? I'm guessing you were a year younger than you would have been, but obviously very dedicated.

Melanie Avalon: Yeah. I was 17 and it was funny. I don't know if he wasn't in my program. The program that I did, they had 20 people that they take every year for that program. Not in my program, but I met somebody else who had done that and that person had actually skipped a year in high school as well. He was like 16 when he went, which is crazy.

Cynthia Thurlow: Oh, my gosh. Especially with a boy I can't even imagine. My son will be 18 in his senior year, and then he'll be 19 when he starts. With boys, they need a little more time to mature.

Melanie Avalon: Yes.

Cynthia Thurlow: And you get the gift of time. Like I always say, I will never regret sending my kids to school when they were 6 and not 5, so I got an extra year with them.

Melanie Avalon: Yeah, that makes sense. Besides the fact that I missed out on some senior-year stuff. I missed our basic econ class and government class, which I just feel like I missed out on some basics that I could have learned from that. I missed out on the literature class from senior year. Besides that, everything felt really normal. Like, it just felt like going to school.

Cynthia Thurlow: I mean, I think from my perspective, there are some people who are just way more emotionally mature and ready for the rigor. Like I say all the time, my youngest is at a [unintelligible [00:17:01] High School, and it's like college. I think college will be easy for him after this, and so he's just ready for it. I'm not so sure my 17-year-old is ready for that amount of rigor, but my 15-year-old is very, like, he sits down and literally comes home and rewrites his notes, tapes his notes, writes his notes, spends a week studying for an exam. I say all the time, like, we aren't doing this. He's doing this all on his own. He's very self-directed and so he's got a fire in his belly and that's innate to who he is as a human being, but I think it'll serve him well.

Like, he has talked about, he already knows where kids have been accepted for college from the high school he goes to. He's like, "Oh, they take this many to this university and this one to this one." Whereas, like, Jack, my oldest son, his high school will take three to the same university. Liam is like, "Oh, our school took 65." [laughs] It's an interesting dynamic, but they're exactly where they need to be. That's why I say, like, very self-directed, mature, focused kids. They might be ready earlier for those kinds of academic challenges and things like that.

Melanie Avalon: People are definitely all different. I'm just thinking back about how different me and my siblings are as well. You also can't really tell I don't know if I should be saying this publicly. My brother had his intense period where he was struggling, but he's, like, doing so well in life now, so people can really, I don't know, come out of anything.

Cynthia Thurlow: Yeah, now. I think anyone that's listening, whether they're reflecting on their own siblings or their kids, everyone kind of matures at a different pace. My oldest is a little more-- he's very smart, but he's a little more laid back. He literally for the first time in his life, has been really challenged in one of his AP classes. I'm seeing the effort he's making and he's doing that very self-directedly and I'm proud of him. You can't motivate him the way that I can motivate my younger one. It's very different. I have to be careful. Like, I'm the gunner. I'm the one that had the fire in the belly. To me, I understand my younger son and my husband understands my older son a whole lot better. We try to make sure we're conscious of that.

Melanie Avalon: I think I mentioned recently I interviewed Seth Davidowitz. His most recent book was Don't Trust Your Gut, but he has a whole chapter on parenting and the effects on children and their ultimate-- how they end up. I might have mentioned this on the show before. I just find it so fascinating. He really makes the case that it's mostly nature, not nurture with the exception of one factor. Did I tell you this? There's one parenting decision that parents can make that seems to really affect how their kids turn out. Otherwise, not so much.

Cynthia Thurlow: Interesting. What is that parenting decision? [laughs]

Melanie Avalon: It's where you live?

Cynthia Thurlow: Yeah, I can imagine.

Melanie Avalon: I guess because of the effects it has on their entire environment and how they grow up. It's where they live and how many adult role models they have that are not their parents.

Cynthia Thurlow: Yeah, it's interesting. To give you an example, so my youngest is a high school freshman and when he was in 7th grade in the midst of the pandemic, one of his teachers led a private class for him and a couple of his peers and they learned Macbeth. So, he knows Macbeth backward and forwards. So, sure enough, what are they reading in freshman year? MacBeth and his teacher said his grasp of concepts is so, first of all, it's unusual that he's interested. Number two, his grasp of the concepts and the nuances is so unusual. And Liam loves it. Like, he feels like a total empowered badass. He's kind of quiet in class, but his teacher said he always has this deep insightful comments. She said does he read Shakespeare on his own? And then I explained the context. Like, in the midst of the pandemic, we were trying to get him to interacting with some of his peers virtually.

This one teacher really took advantage of the fact that he could get them to be interested in Shakespeare. He still talks about this teacher how much of an impact he had on him and how grateful I am that during the pandemic, he was able to, A, be interested in learning about something and B, takes such a lead in his own education. He didn't turn it off. He just leaned in and learned and really enjoyed it.

Melanie Avalon: Yeah. No, that's amazing. Yeah, there's definitely that type of reading. All the things that's what I was doing growing up.

Cynthia Thurlow: Yeah. I could imagine you were like a little budding Liam, but the girl version, I get it, totally get it.

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To make it easy, Athletic Greens is going to give you a free one-year supply of immune-supporting vitamin D and five free travel packs with your first purchase. All you have to do is visit athleticgreens.com/ifpodcast. Again, that is athleticgreens.com/ifpodcast to take ownership of your health and pick up the ultimate daily nutritional insurance.

Well, shall we jump into fasting-related things for today?

Cynthia Thurlow: Sure. Our first question is from CC, subject is "Ashwagandha and diabetes. I love your podcast. I would like to know if taking ashwagandha breaks your fast. I first read about it in the Prime Diet and started taking it before intermittent fasting, but I'm now afraid it will break my fast. My second question is on the link of intermittent fasting to diabetes. I'm so excited about fasting but just heard of the recent study that links fasting to pancreatic damage and type 2 diabetes. I have diabetes in my family history, but I'm very careful what I eat, more low carb, but this new study is scary. What are your thoughts? Thanks."

Melanie Avalon: All right, CC thank you so much for your question. Well, for the first one, for ashwagandha. Assuming it is just pure ashwagandha, it should not break your fast. I don't really do much with adaptogens, but you are a fan of adaptogens, right?

Cynthia Thurlow: I love adaptogens for many reasons and ashwagandha is one of these really flexible adaptogens, meaning it can be helpful for balancing cortisol. It can also be very calming, so you can take it sometimes in the morning and it can be energizing, and then you can take it in the evening and it can be balancing if you're feeling like your cortisol is high. It's also one of the best-researched adaptogens.

Melanie Avalon: I've taken ashwagandha a little bit. I personally didn't notice many benefits, but I know a lot of people have. Is it a nightshade? People say that.

Cynthia Thurlow: Yes, it is. If you're sensitive to nightshades, you want to avoid ashwagandha.

Melanie Avalon: Okay. The ones I have tried, I've responded well to Rhodiola.

Cynthia Thurlow: Yeah, Rhodiola is great at nighttime. I think my other favorite is probably Relora, so it's derived from magnolia bark and it's very calming, and that's a great one to take at night.

Melanie Avalon: Oh, interesting. The Rhodiola always made me energetic, so I would take it during the day.

Cynthia Thurlow: Well, it's interesting. Out of all the patients I've taken care of, I had one woman who swore it made her wide awake at night.

Melanie Avalon: The Rhodiola?

Cynthia Thurlow: Yeah. I think that has some bio-individuality, meaning, from that point on I stopped using it not necessarily with every patient, but I really started leaning into other options like Relora, which is really nice and very calming and nourishing for the brain.

Melanie Avalon: Awesome. Do you think you'll make some adaptogens in the future?

Cynthia Thurlow: I do, although I tend to be kind of a purist and so I definitely think about either a sleep blend or something that will be helpful in the morning to be energizing. I mean, I've vacillated back and forth, but I think most of my focus is going to be either on sleep support or things that are going to help with insulin sensitivity or muscle growth or muscle performance. I think initially those are going to be my focus, so I do think adaptogens will be part of that. It's just figuring out what's the right blend because when you start blending things together, you don't always know what's working and what isn't versus if it's just creatine or just one type of like magnesium L-threonate, which I love. You have a better sense, is this working for someone or not?

Melanie Avalon: Yeah, no, that's so true. I agree about the single things because otherwise you won't know. I guess speaking of things that really benefit blood sugar control, my berberine launched, when these airs it will have launched 10 days ago. So hopefully people stocked up. If you would like to get that, we are actually having a special. The special ends at the end of this month. Stock up now at avalonx.us, the special is you get 15% off of one bottle or 25% off of two or more. This is really the time to stock up. I've really been honestly floored because I was taking berberine originally just for blood sugar control, but after deciding to make it, I've really been researching all of the other benefits and it's overwhelming all of the benefits. GI health, obviously blood sugar control, reducing blood sugar, reducing cholesterol and lipids.

When it comes to the gut microbiome, it seems to increase beneficial bacteria and decrease more problematic bacteria. Actually, it helps the body's reaction to LPS, which is the toxic byproduct of bacteria. They think that actually might be a mechanism for how it affects blood sugar, which is interesting, which just speaks to how intensely our gut health relates to our overall metabolic health. I think our gut microbiome is affecting things way more than we realize.

Cynthia Thurlow: Oh yeah, I totally agree with you. It's interesting. I did IG Live, I'll be bringing Dr. [unintelligible [00:29:04] on the podcast in January, and she's a gastroenterologist, like a functionally focused gastroenterologist, and she has this great book that just came out talking about the role of viruses in the gut microbiome. It's really apparent to us that she and I trained over 20 years ago and Lord knows we knew very little to nothing about the gut microbiome. And it's almost like peeling an onion. The more you learn, the more humbled I am. That's actually going to be, it's called the antiviral gut, but she was fantastic and I cannot wait. I don't do many IG Lives anymore, but she was well worth the IG Live. That was definitely a highlight of my week.

Melanie Avalon: Yeah, that's amazing. We just don't even realize and I will comment though quickly, that the primary mechanism of action for berberine reducing blood sugar, I mean, I don't know, it's probably not the gut microbiome. It specifically affects pathways in the liver and can downregulate the liver's production of glucose and also can affect glucose absorption and utilization and insulin and things like that so yep. Again, the link for that is avalonx.us. Through the end of the year, you can get 15% off of one bottle and 25% off of two or more, and then after that you can use the coupon code MELANIEAVALON to get 10% off and that code will get you 10% off sitewide as well.

Okay. And then for CC's second question. She wants to know about the link of IF to diabetes. I am not sure what study she's referring to. I researched, I searched a lot to try and find a study talking about intermittent fasting encouraging diabetes and I think I found it because the study came out, it was in 2018, it was called "Could Intermittent Fasting Diets Increase Diabetes Risk?" It was published in the European Society of Endocrinology. It was one of those studies, Cynthia, how these studies come out and then all the headlines are talking about it. That was the case with this one. What's really interesting is it's no longer on the website, so I can't find the actual study. I'm guessing the study got, was it redacted? What's weird is they don't have a note. It just no longer exists. I'm thinking she was probably talking about that study and I'm thinking something happened with that study to the fact that they don't have it published anymore.

In any case, what it was looking at was it was a study in rodents and they put them on fasting diets and they found that, I think it was an ADF approach every other day, and they found that the rodents did lose weight, but their insulin went up and they gained visceral fat. The conclusion or the hypothesis was that even if fasting was resulting in weight loss, it was actually encouraging diabetes and metabolic issues by its effect on insulin. Stepping back from that well, first of all, like I said the study is gone, something happened with it which is suspect. Moving beyond that, I could not find and maybe I didn't search enough, but I could not find any other studies saying this. The overwhelming majority of literature on fasting is that fasting has a very beneficial effect on insulin, on diabetes risk, on things like that.

For example, a much more recent meta-analysis from 2021 called "Intermittent Fasting: Is there a Role in the Treatment of Diabetes?" A review of the literature and guide for primary care physicians. Like just reading from it, it literally says, "The majority of the available research demonstrates that intermittent fasting is effective at reducing body weight, decreasing fasting glucose, decreasing fasting insulin, reducing insulin resistance, decreasing levels of leptin, and increasing levels of adiponectin. Some studies found that patients were able to reverse their need for insulin therapy during therapeutic intermittent fasting protocols with supervision by their physician. Current evidence suggests that intermittent fasting is an effective nonmedicinal treatment option for type 2 diabetes. More research is needed to delineate the effects of intermittent fasting from weight loss." The long story short takeaway is whatever study CC saw that one or another, I would not be worried about intermittent fasting for increasing diabetes risk. I think the overwhelming majority of data supports the opposite. Cynthia, do you have any thoughts?

Cynthia Thurlow: I do. It's interesting. This is always a good example of cherry-picking research and data mining and the catastrophizing that goes on in the media when people don't know how to read research. I would concur with you that everything that I read and everything that I look at really supports this carb-insulin hypothesis. For someone to somehow suggest that intermittent fasting, which is our ancestral birthright, is somehow going to create pancreatic damage and contribute to diabetes, I think is really dangerous because we as humans are not designed to eat the way that our modern day lives have kind of embraced. It just makes me sad that someone propagated an idea that was picked up by mainstream media that suggested that this would somehow be harmful. In fact, I have Dr. Jason Fung's book sitting in front of me because my intermittent fasting coaches are reading this month.

The Obesity Code talks a great deal about relevant and current research that supports this hypothesis of carbohydrate restriction. That doesn't mean carbohydrates, but I definitely am a fervent believer in carbohydrate restriction for people who are metabolically unhealthy and certainly those that are insulin resistant. I always say knowledge is power and if you know that you are metabolically healthy and metabolically flexible, then you can adjust your carbohydrate consumption accordingly. To suggest that somehow, it's going to damage your pancreas. Type 2 diabetes is a lifestyle disease. Let me be very clear. Type 1 diabetes is an autoimmune destruction of the beta cells in the pancreas, very different. To somehow suggest that nutrition is playing a role in type 1 versus type 2 is unfortunate.

Melanie Avalon: I keep saying it, but I find that really interesting that that study is just gone.

Cynthia Thurlow: Yeah, redacted, and it's probably because it's garbage.

Melanie Avalon: Normally, even if a study is not good, you can still find it. It's still up on the Internet. The fact that it's just gone is very weird, but telling?

Cynthia Thurlow: It's a fascinating development.

Melanie Avalon: Yes, it is. Of course, just to comment on what you were saying about the sensationalization of these findings and such, they're not going to come out and say, "Hey, study was redacted." There's not going to be a whole new swarm where they say that this was undone. If you were saying this, it's concerning that these ideas can get out there that might not be accurate, and they can be just so sensationalized and presented as truth. It's hard to unlearn something that you were exposed to even if it wasn't true because once you hear it. By the way, I'm not discouraging different findings coming out. I'm all for all the different findings and questioning things. It's just the problem comes when most people aren't going to actually look at the source material and think about it and they're just going to listen to or many people I should say most, but many people will just listen to the news and take what they say, which also will be a slightly bastardized version of the original source material.

Cynthia Thurlow: I always say it's the rabbit hole that you have to dive down. Like, someone got excited about some creatine research and they shared it with me and I said, well, it's an N of 26, so the potentiality exists that there might be something worth investigating, but it needs to be statistically significant. That's more often than not what I see is various small sample sizes and then they extrapolate from that and then convince people, "Oh, this thing that you've been doing for five years is no longer healthy." It's like, "Wait a minute, let's look at the data, let's look at the research, let's be thoughtful." And I agree. I hope listeners know that we're always happy to read stuff that's contrary to our own opinions. I think that's part of just being an intellectually curious human being. It's like show me the evidence and let me look at it and then we can decide if it will encourage us to form a different opinion or if it just validates what we already think.

Melanie Avalon: Exactly. I want to know, like, tell me why I'm wrong. That's why I love reading different opinions for me, I love it. I want to know where I'm thinking incorrectly. I would like to know that that would beneficial. I'm not wedded to any one answer or at least as much as I cognitively perceived myself not being wedded to. I know we all have biases that are really hard to see past, but I really do try to be open.

Cynthia Thurlow: Absolutely.

Melanie Avalon: Okie Dokie. Shall we answer another question? This actually relates to what we're just talking about with your creatine. Nikki says "Hi, Melanie and Cynthia. I would love for you to discuss the science behind creatine a bit more, especially after learning Cynthia has a creatine supplement coming out soon, which is actually now out. I have some Thorne brand and try to take it when I remember, but I'll admit it could be a bit more consistent. I'm a questioner under Gretchen Rubin's The Four Tendencies framework, so it helps me to know why when I'm trying to make something a habit. My question is why is creatine necessary even if you're meeting your protein requirements? In my case, 130 to 145 g a day. My other question is, when is the best time to take it? Thanks for all you do."

Cynthia Thurlow: That's a great question, Nikki. What I can tell you is we don't get enough of creatine, let me just back up, our bodies have 70% to 80% less endogenous creatine sources compared to men, so that's number one. Number two is if you look at the research irrespective of life stage, women have differing needs. When you're menstruating at specific times during your menstrual cycle, you can benefit from a little bit more supplementation. I just reviewed a study this afternoon looking at menopausal women and the same could apply to perimenopausal women as they are losing estrogen, they have greater issues with muscle-protein synthesis and so supplementation could beneficial there as well. What I would say is that we don't get enough from animal-based protein because I would love to say just eat more protein. That's not going to do it. We need this specifically for ATP and the muscle so supplementation is going to be very beneficial.

I have personally been using this for over a year, obviously just only recently using my own product because it wasn't available before. My trainer last year started talking to me about it and there's a lot of really good research. Dr. Gabrielle Lyon is 100% on board with the utilization of creatine in women. To me, since a lot of the focus of my work is really talking about metabolic health and maintaining muscle mass, and gosh darn it's so much harder at 51 maintaining muscle than it was 20 years ago. I just never appreciated it. I wanted to introduce something that would be helpful for women throughout their lifetime. I would recommend taking it during your feeding window, not during your fasting window. Melanie and I were talking about this earlier and I was saying I put it into a smoothie and that's how I choose to consume it.

It doesn't have a taste and it's not granular. That's one of the things that the mix ability is high. There was another product that will remain nameless that I've used in the past and it's almost crystallized, so it was harder to get it to blend easily with liquids. That would be my recommendation. And, yes, I am very familiar with Gretchen Rubin's The Four Tendencies framework. I actually was on TV. Yeah, it's interesting. I was on TV with her.

Melanie Avalon: Oh, really?

Cynthia Thurlow: Yeah, when I say on TV with her, when I was at our local ABC affiliate in Washington DC, I got to meet her. At the time I didn't know who she was. I'm embarrassed to admit that. I loved what she talked about so much that I went out and bought the book and every time I worked with a new client one on one, I would give them the quiz.

Melanie Avalon: I feel like I'm so obvious what I am. All I needed was a summary of that book and I was like, yeah, I know exactly what I am.

Cynthia Thurlow: I'm not the questioner. I think I was the upholder, no I wasn't the upholder, obliger.

Melanie Avalon: For listeners, it's whether you uphold inner versus outer expectations. If you uphold inner and outer, so inner being you and then the outer being what other people are asking of you. Let's see if I can remember this. If you uphold both, you're an upholder. If you uphold your inner but not other people's, you're a questioner. If you uphold other people, but not your own, you're an obliger. If you just reject everything, you're a rebel.

Cynthia Thurlow: I really feel like, honestly, I'm a little bit of two. I wouldn't describe myself and I think when I took it, I was kind of on the fence about what direction I headed and I think the younger me would have been the obliger. I was never the rebel, although I've had many rebel clients and then I have to remind myself but the questioners, the ones who always ask a lot of questions, it explains so much and anyone who is comfortable and confident with who they are would never see that as a negative. It's a curiosity piece for me.

Melanie Avalon: Yeah. I agree. For you, I always say either well, I was thinking either a questioner or an upholder.

Cynthia Thurlow: I'm a little bit of an upholder, but I'm not rigid and judgmental. That's the one thing that didn't-- I'm much more I always say I don't use the term libertarian lightly. I'm just saying I just accept people where they are. I'm not particularly judgmental unless you're bad to children and animals. I do have strong opinions, but that's a whole separate conversation.

Melanie Avalon: Yeah, I do think the layer of how you perceive it, I feel like you could withhold or not withhold inner versus outer within the layer of how you, like the judgment layer would be separate. You could be judgmental in all of it or judgmental and none of it. I can see how certain personality traits would probably more likely lead to others.

Cynthia Thurlow: Absolutely. I really like her work and I listen to her podcast and I don't know if anyone else has this issue, but I definitely feel like we need more strong female role model podcasters. Do you feel that way?

Melanie Avalon: It's funny, I was recording just yesterday with Elle Russ, who I adore, and we were talking about because she was the cohost and host of the Primal Blueprint podcast for so long and now she has her own show, The Elle Russ Show. We were talking about the role of women, and yeah, there is like a lack maybe. I guess a lot of the podcasts, I'm just thinking to what I listen to. I guess it is a lot of men.

Cynthia Thurlow: I mean, the ones I listen to, like if I really am honest with listeners, I tend to lean into some of the male ones because my husband was making fun of me because we listened to Huberman Lab all the way to DC and back because Huberman Lab was recording with BioLayne. It was almost a four-hour podcast. It was craziness, but only because I was in the car and my husband was like, "Oh, my God, this is so dry." [laughter] I was like sometimes I just want to learn. I just want to absorb as opposed to just be entertained. I think some of the male-dominated podcasts do a nice job with that. It just depends on my mood. There's definitely there's probably, like, six male-dominated podcasts I lean into, and then I listen to yours. I still need to listen to the glutathione one and a few others, but it's probably more, it's more like male-centric. Not on purpose, but they tend to be more, I don't know, data-driven, less fluff.

Melanie Avalon: Yeah, that's true. I'm just thinking I listen to, well, like Robb and Nicki, so that's both Robb Wolf, Peter Attia. I don't listen regularly to Huberman. I listen to Rich Roll all the time.

Cynthia Thurlow: I need to listen to Rich.

Melanie Avalon: Have you listened to him before?

Cynthia Thurlow: I have not.

Melanie Avalon: This actually speaks to what I was talking earlier about having an open mind. The reason I listen to him primarily is because he's very vegan. He provides a very different perspective because I'm so seeped in the keto and carnivore world. Listening to a vegan-driven podcast I find very helpful and I find him very open-minded. I find him very comforting. He interviews a lot of people that I interview as well, so he interviews people that I'd be listening to anyways. I feel like I get a different perspective coming from him and I just find him very calming. I listen to him at night and I listen to Mikhaila Peterson. I like her podcast.

Cynthia Thurlow: I don't know her.

Melanie Avalon: She's spicy. Jordan Peterson's daughter.

Cynthia Thurlow: Don't know her.

Melanie Avalon: Yeah, she got popular, well, her dad's Jordan Peterson, so that helped. She had a whole thing with carnivores and she went on Joe Rogan and talked about her carnivore experience and that kind of shot her up, so podcasting, I'm just always grateful that I'm in this world because there's so many podcasts I like. Don't take it for granted that we have some amazing podcasts with an amazing audience because it's not easy.

Cynthia Thurlow: No, no. And it's interesting. I'm part of a podcast mastermind and I'm at a different stage in my business and my podcast, so I'm oftentimes giving advice to people in the group, which I lovingly do because I really enjoy this group of women, and I forget how. I don't think we tracked metrics the whole first year we were podcasting. Really, I didn't start taking podcast metrics seriously until Kelly and I, so Everyday Wellness used to be a co-hosted podcast with a friend of mine who's a clinical psychologist. It was kind of her idea and then a little bit over a year in she was less interested in doing it, and it was either sink or swim. It wasn't until 2020 that I started paying attention to those things. I said, okay, I'm going to swim, I'm not going to sink, I'm not going to turn this over. From my perspective, I think that loving what you do is certainly very evident.

I know Gin and you created this amazing community of which I'm very grateful to be a part of, and then our own ecosystems that are separate from Intermittent Fasting podcast. There's no doubt that your podcast in particular is, you do a fantastic job interviewing people and exposing me to new information, new ways of thinking about things and that's really what it's all about.

Melanie Avalon: Yeah, no, I as well, I'm so inspired by everything that you're doing. It's so incredible. It's almost eerie the overlap, well, we have a lot of overlap in our guests and who we interview and everything, but we also have different like, I feel like yours is more menopausal and women's issues and hormones skew and then mine is just like all over the place, like deuterium-depleted water.

Cynthia Thurlow: I think mine is skewed because I know that nothing prepared me for being middle aged, and it's not like intellectually I wasn't prepared, but no one had talked to me about the things that were going to happen. I'm like if my experiences can help someone else and if I can bring on guests that can speak to that, I mean, I know my listeners and I know what's going to resonate. I know I can offer alternative perspectives, but I know what content is really going to resonate. It's been validated so frequently that now I don't ever want to be an echo chamber because as an example I had that scientist talking about that form of tocotrienols, annatto and how that can be helpful for bone health, which I think is significant for all of us. I never would have imagined that his research would really like resonated steeply.

Like, I watch all my metrics, I'm a little OCD about it. I only do it once a day, but I know exactly what content resonates and perimenopause and menopause are women north of 35. That's really who we speak to. I think that you bring on guests that have got a very wide, diverse opinions, and I think that's wonderful. I think it's important for all of us to not be an echo chamber because it's easy just to stay stuck in one spot.

Melanie Avalon: Yeah, so incredibly true. All the more knowledge, all the more things the merrier. I imagine I probably will, when I get to that point in my life, have a much uptake and interest, and I'm interested in it now. Just what you were talking about with what you experienced and the focus there.

Cynthia Thurlow: Oh, goodness. I want everyone to avoid what I did. I hit the wall and I thought I was doing everything right. I'm completely sensitive to when people tell me I don't know what I'm doing wrong. I'm like, "Oh, it's all hormones."

Melanie Avalon: I was talking about this with Elle yesterday. Having gone through health issues really can be a benefit because A, it makes you learn so much about the topic and gives you agency to take care of yourself and feel better, but then also just gives you complete empathy for other people having similar things.

Cynthia Thurlow: Absolutely.

Melanie Avalon: I feel you people when you're struggling.

Cynthia Thurlow: Benefit from what we've learned that's what I would say for everyone.

Melanie Avalon: Hi, friends, exciting announcement. You guys know I love blue light-blocking glasses. I wear them every single night of my life. My favorite blue light-blocking glasses company, Bon Charge, is having a massive 25% off sitewide sale until January 2. Now is the time. I am often asked what are my favorite, "Biohacking products?" Something I truly, honestly cannot imagine my life without our blue light-blocking glasses. In today's modern environment, we are massively overexposed to blue light. It's a stimulating type of light, which can lead to stress, anxiety, headaches, and in particular sleep issues. Blue light actually stops our bodies from producing melatonin, which is our sleep hormone. Our exposure to blue light can completely disrupt our circadian rhythm, make it hard to fall asleep, make it hard to stay asleep, and so much more. Friends, I identify as an insomniac. I would not be able to sleep without my blue light-blocking glasses. I also stay up late working and wearing blue light-blocking glasses at night has made it so I can do that and still fall asleep. My absolute favorite blue light-blocking glasses on the market are Bon Charge, formerly known as BLUblox. 

Bon Charge makes an array of blue light-blocking glasses in all different designs, so you can truly find something that fits your style and reap all of the benefits of blue light blocking. They have clear computer glasses. You can wear those during the day, especially if you're looking at screens all day to help with anxiety, headaches, and stress. They have their light sensitivity glasses, those are tinged with a special yellow color scientifically proven to boost mood and they block even more blue light. Those are great for the day or evening. Then they have their blue light-blocking glasses for sleep. Those are the ones that I put on at night while working before bed. Oh, my goodness, friends it's something you truly have to experience. You put on these glasses and it's like you just tell your brain, “Okay, it's time to go to sleep soon.” They also have amazing Blackout Sleep Masks. Those block 100% of light with zero eye pressure. I wear this every single night and I don't know how I would sleep without it. I'm so thrilled because Bon Charge is currently having a Boxing Day sale, which is 25% off sitewide until January 2. Just go to boncharge.com and choose your favorite wellness products and the discount code will automatically be applied at checkout. That's B-O-N-C-H-A-R-G-E dotcom and the 25% off will automatically be applied at checkout. If you're listening after the sale ends, you can use the coupon code IFPODCAST for 15% off and we'll put all this information in the show notes.

All right, shall we go on to our next question?

Cynthia Thurlow: Sure. "Hi, ladies. New to intermittent fasting and I'm slowly working my way through your fantastic and informative podcast. I am a 24-year-old lean male who is looking to move from 14% body fat to 10% and really get those abs popping for summer. I have followed calorie restriction for a year with no consistent and lasting results. I exercise six times per week, badminton, squash, HIIT resistance training, and football and I'm worried my calorie deficit is too large. I eat approximately 1500 calories per day regardless of how much intense cardio I do. Am I in danger of losing muscle or any other adverse health effects of a deficit that is too large? I eat 10:30 AM to 6: 30 PM and have the above commitments in evenings to start my fast with exercise. Will this also get me into ketosis faster, by starting the fast with exercise? You are both awesome and keep up the good work. Many thanks, Alex."

Melanie Avalon: All right, Alex, thank you so much for your question. You're a 24-year-old male, already lower body fat, doing a massive amount of exercise, and eating a very calorie-restricted diet. I'm guessing that you're doing the calorie restriction because you are trying to achieve these certain goals, which completely makes sense. I am all for people going for whatever goals they want to go for. So, I support in that aspect. That said, I would definitely focus on adequately fueling yourself. I would be worried about losing muscle from that deficit because how long you said you've been doing calorie restriction, for a year with no consistent and lasting results? This is my suggestion, but I would have a complete mindset shift with the food. I would stop counting calories. I would eat to satiety. I would let fasting do its magic. If you are going to focus on something food wise, I would focus on the macronutrient aspect of things, especially if you're pursuing certain body fat goals.

I would focus on protein. Making sure that you're getting adequate protein, especially if you're concerned about maintaining muscle and not losing muscle. From there you can get a lot of benefits. I say this all the time, but you can get a lot of benefits by doing either lower carb or lower fat. There's a lot of metabolic magic that can happen when you're playing with the macros and not restricting calories. You've been doing this for a year. It's a very severe calorie restriction and it's not working. So, I would not keep doing it. I would definitely mix things up. As far as will you get into ketosis faster by starting the fast with exercise? Yes and no, so quite probably you will burn through your glycogen faster and potentially enter ketosis faster. The only slight difference is you could be doing very glycolytic-demanding activity. The actual exercise itself might be a carb-fueled workout if that makes sense. On the flipside, in theory, you should be entering ketosis faster. Do you have thoughts, Cynthia?

Cynthia Thurlow: I do. I'm genuinely concerned about the restriction of macronutrients, especially if you're working out six days a week, which is pretty dedicated and intense, and you're doing two days of strength training and you are very likely putting yourself in a position that you are not going to be able to maintain muscle mass. Your body will probably catabolize some of your muscle to make up for the lack of macronutrients you're consuming. Ted Naman talks a great deal about thin people doing this and I always refer to it as the triad, the over fasting, overexercising, over restriction of food. I think we can unknowingly get into some trouble when we're eating in a deficit for too long a period of time. At a minimum, I think that you need to back off on the fasting. I would imagine that simply by maybe swapping out some cardio for some strength training and being very targeted with your macronutrients, especially protein and appropriately timed carbohydrates could allow you to get to the point where you could lean out.

I think at this point you're leaving your body in a deficit where it's depleted. As I mentioned earlier, I think you're putting yourself in a position where you're going to end up catabolizing or breaking down your muscle to fuel your body. Certainly 24 years old if your testosterone is optimized or growth hormone, et cetera, you really don't want to be putting yourself in a deficit like that all the time. I would definitely back off on the intensity work on a recovery day. Maybe instead of doing HIIT and all that explosive movement, give yourself another dedicated day of strength training. I would have three meals a day to make sure you're getting at least 1 gram per pound of ideal body weight of protein because I would imagine you're depleted all the time.

Melanie Avalon: This is like a massive, massive deficit.

Cynthia Thurlow: That triad, I talk about, jokingly people are like, what's your next book going to be on? I'm like it's not going to be about the triad, but I'm starting to talk more about it, this over fasting, overexercising, over restriction, which ends up depleting your entire endocrine system and can put people in some situations where they're heading in the opposite direction. High cortisol, which can lead to high insulin, high blood sugar. This is when you see people that they don't understand the interrelationship of all of these hormones when their body is in a chronically stressed, sympathetic, dominant state.

Melanie Avalon: Well, this has been absolutely wonderful. By the way, Cynthia, my face is completely numb right now. It was like slowly, like, numbing during the show. I was like, "Well, what is happening?" This has been absolutely wonderful though. For listeners, if you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. You can get all the stuff that we like at ifpodcast.com/stuffwelike. Do we mention your link, Cynthia? How do people get creatine?

Cynthia Thurlow: www.cynthiathurlow.com/creatine.

Melanie Avalon: And for the berberine, avalonx.us/berberine. And you can follow us on Instagram, we are @ifpodcast, I am @melanieavalon, Cynthia is @cynthia_thurlow_. This has been absolutely wonderful. I will talk to you next week. 

Cynthia Thurlow: Sounds good. Enjoy your appointment.

Melanie Avalon: Thank you. Bye.

Cynthia Thurlow: Bye.

Melanie Avalon: Thank you so much for listening to The Intermittent Fasting Podcast. Please remember everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team, administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and re-composed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Nov 27

Episode 293: Holiday Feasting, Liquid Chlorophyll, Iron Supplementation, Anti-Inflammatory Foods, Sauna, Signs of Ketosis, And More!

Intermittent Fasting

Welcome to Episode 293 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

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To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get Free Ground Beef for Life and $20 off your first order!!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

FEALS: Go To feals.com/ifpodcast To Become A Member And Get 50% Off Your First Order, With Free Shipping!

Listener Q&A: Kasi - Liquid Chlorophyll during fast // Window Flexibility // Anti-Inflammatory Foods

The Melanie Avalon biohacking Podcast Episode #43 - Teri Cochrane

Episode 56: The Cochrane Method and Bioindividuality

Ep. 201-The Connection Between Genes, Detoxification, Hormones, and Immune Function

Go to melanieavalon.com/ancestral and use the code AVALON10 for 10% off Ancestral supplements!

Go To melanieavalon.com/aura And Use The Code AVALON For 10% Off Aura Glutathione!

The Melanie Avalon Biohacking Podcast Episode #149 - Chris Masterjohn

The Melanie Avalon Podcast Episode #61 - Dr. Cate Shanahan

BON CHARGE: Go To boncharge.com For A Black Friday Sale with a massive 25% off sitewide until 30th November!

Listener Q&A: Bruce - Thanks for all you do

Why Combine Sauna and Fasting

SUNLIGHTEN: Get Up To $200 Off AND $99 Shipping (Regularly $598) With The Code MelanieAvalon At MelanieAvalon.Com/Sunlighten. Forward Your Proof Of Purchase To Podcast@MelanieAvalon.com, To Receive A Signed Copy Of What When Wine!

Listener Q&A: Justine - signs of ketosis

Lumen, Biosense & CGMs: Carbs, Fat, Ketones & Blood Sugar (Melanie Avalon)

get $20 off of Biosense. If you go to melanieavalon.com/biosense and use the coupon AVALON20

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 293 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: A 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine if it's that time and get ready for The Intermittent Fasting Podcast.

Hi friends, I'm about to tell you how you can get free grass-fed, grass-finished beef for life plus $20 off, yes free grass-fed, grass-finished ground beef for life plus $20 off. We are so, so honored to be sponsored by ButcherBox. They make it so, so easy to get high quality humanely raised meat that you can trust. They deliver 100% grass-fed, grass-finished beef, free-range organic chicken, heritage breed pork, that’s really hard to find by the way, and wild-caught sustainable and responsible seafood shipped directly to your door. When you become a member, you're joining a community focused on doing what's better for everyone. That includes caring about the lives of animals, the livelihoods of farmers, treating our planet with respect, and enjoying deliciously better meals together. There is a lot of confusion out there when it comes to transparency regarding grazing practices, what is actually in our food, how animals are being treated. I did so much research on ButcherBox, you can actually check out my blog post all about it at melanieavalon.com/butcherbox. But I am so grateful for all of the information that I learned about their company, all of their beef is 100% grass-fed and grass-finished. That's really hard to find. They work personally with all the farmers to truly support the regenerative agriculture system. I also did an interview with Robb Wolf on my show, The Melanie Avalon Biohacking Podcast, all about the massive importance of supporting regenerative agriculture for the sustainability of not only ourselves but the planet. This is so important to me. I'll put a link to that in the show notes. 

If you recently saw a documentary on Netflix called Seaspiracy, you might be a little bit nervous about eating seafood. Now, I understand why ButcherBox makes it so, so clear and important about how they work with the seafood industry. Everything is checked for transparency, for quality, and for sustainable raising practices you want their seafood. The value is incredible, the average cost is actually less than $6 per meal and it's so easy. Everything ships directly to your door. I am a huge steak lover. Every time I go to a restaurant, I usually order the steak. Oh, my goodness, the ButcherBox steaks are amazing. I remember the first time I had one and I just thought, “This is honestly one of the best steaks I've ever had in my entire life.” On top of that, did you know that the fatty acid profile of grass-fed, grass-finished steaks is much healthier for you than conventional steaks? And their bacon, for example, is from pastured pork, and sugar and nitrate free. How hard is that to find? And ButcherBox has an incredible deal for our audience. For a limited time, you can get free grass-fed grass-finished ground beef for life in every box of your subscription plus $20 off, yes, new members can get free grass-fed grass-finished ground beef for life plus $20 off when you go to butcherbox.com/ifpodcast. That's butcherbox.com/ifpodcast for free grass-fed grass-finished ground beef for life plus $20 off and we'll put all this information in the show notes. 

And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting, it's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters which mess with your hormones, carcinogens linked to cancer, and obesogens which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup may be playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That's because ladies when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years.

Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means, when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so, you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life. And their makeup is amazing. Check out my Instagram to see what it looks like. Tina Fey, even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well. 

And lastly, if you're thinking of making Clean Beauty and Safe Skincare, a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now back to the show.

Hi everybody and welcome. This is Episode number 293 of the Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hey, Melanie, how are you?

Melanie Avalon: I'm good, I just checked when this is going to air. I wish I could ask you, how was your Thanksgiving but it has not happened as of right now. But I am super curious since this is the Intermittent Fasting Podcast. How do you tackle Thanksgiving with fasting?

Cynthia Thurlow: This year is a good example of--it's just the four of us, which I'm super excited about because it's really only the second holiday we've spent in our new home. I don't alter a whole lot to be honest with you, we eat earlier in the day, we usually eat by 3 or 4 o'clock. My teenagers will go back for seconds a few hours later, but I'm generally not hungry. I may have like a light meal to break my fast and then really lean into protein and veggies and that's one of the few times in the year I will enjoy pie like I make a really good apple pie. And there's something about even gluten-free crust that I love which is why I don't normally eat pie, but I will allow myself to enjoy and savor every single bite.

I think that I don't treat Thanksgiving any differently than really any other day because I don't alter the way I eat too much. And it's not to say that I can't, I just don't feel good when I eat certain types of foods. So, my kids get a lot of the starchy stuff like stuffing and potatoes and I'm the one that leans into like Brussel sprouts and other things that we might have alongside, the last couple of years we've been doing tenderloin and not turkey but ButcherBox very nicely sent me a lovely turkey. So, we will be having some turkey and some tenderloin for Thanksgiving.

But it's also the one holiday that my husband gets really into and wants to make everything himself. All these women listening, they're like, "Oh my gosh, I wish my husband would do that." He gets a little controlling about his kitchen on Thanksgiving, I really play an ancillary role on Thanksgiving and I'm completely fine with that because he's a really good cook. But it's sometimes an odd dynamic because I think we're kind of conditioned as a society that it's the woman in the kitchen all day long. And actually, it's my husband like up early for the bird and he's all about making the stuffing. And every year he perfects his stuffing and he makes this is horrible, Chex Mix. And so, Chex Mix is like a crack in our house, my husband and my kids will eat it till it is gone. But I jokingly tell them, they need a feed bag just to put the strap on over the back of their neck and just let them eat it all day long, and they could not be happier. There's a lot of feasting in our house. It's usually a pretty relaxed day. How about you?

Melanie Avalon: Similar to you, I personally don't really adjust much. Because doing my one-meal-a-day approach that I do. I literally am feasting already every single day. And, for example, it was my birthday this week, and a friend came in town and we went to dinner. And I got two entrees. It was because I wanted to-- I couldn't decide, I wanted both steak and fish, so he was like just get both. But I was like, "Okay, I'll have like a bite of the steak and eat the fish, but I ate all of it." [laughs] which was fabulous. And that's an addition to the appetizers and all of that. But the point being is, I am so accustomed to eating large amounts of meat at night and protein, so on Thanksgiving nothing really changes much because the foods I want to eat what you were saying about, the foods that make you feel good and the foods that don't, I would like to eat a lot of other different foods that would also taste good, but they would also make me feel not so well. Or I can eat the foods that taste just as good to me but make me feel great. On Thanksgiving, I would still do my one-meal-a-day type thing and just eat a ton of Turkey as my meat.

Cynthia Thurlow: And I think it's interesting because for me personally, this is what my life has evolved into. And I'm completely happy in the space. But I do know, when we have like family or friend's events, people always kind of look at me and they're like, "Well, you're not going to have this and you're not going to have that? And I'm like, "No, because I actually don't feel good when I eat X or Y. And I'm totally fine with you eating X or Y. It's just not what I'm leaning into. I think it's also like being respectful. Sometimes it can be very triggering when people see you eat a particular way, then I always say there's no judgment, I just know that I'm at a stage in my life where it's not worth it for me to eat foods that make me feel badly. Like if I were to have a couple of glasses of wine, guess what my sleep is going to be terrible. I'm going to get hot sweats, night sweats, and I'm going to wake up in the morning and my Oura Ring is going to be barking at me.

From my perspective, it's a cost-benefit, like what makes me feel good, what allows me to wake up on the day after Thanksgiving, and whether we're doing a 5k, we try to do things that are active, and you're asking what the prevailing strategy is, move my body, try to lift if not on Thanksgiving, the day before or the day after, stay really well hydrated, and then choose the things that you want to splurge on and typically mine is apple pie. [laughs] I love apple pie, I love apples in general. But I love, I make a really good apple pie. It's very basic, but it's really good, and my kids laugh because I'll stand there at the counter, and I'm just eating the crust. Like I wouldn't normally eat crust I am like, "Oh, this is good."

Melanie Avalon: Yeah, one of the things I really like about fasting though, in general, with the holidays, like before fasting, I would have a lot of fear. I would love the holidays and I would love the food, but I would have a lot of dread or concern about overeating, weight gain, overindulging, and it was this weird blend of the pure excitement and joy of the food and also dreading the aftermath. And now I never really experience that, like holidays I just genuinely look forward to the whole food experience with minimal, I mean really honestly, no negative effects.

Cynthia Thurlow: Yeah, I mean, to me, especially because I have teenagers and I recognize that time is fleeting with them. I've always loved our nuclear family and prior to the pandemic, we always spent holidays with our extended family. And now things have changed a little bit and that's okay. But for me, it's really the joy of having conversations with my kids because as teenagers they spend a lot of time connecting with their friends or disconnecting from their parents. And so, for me we get into these discussions of "Are we going to do like a Harry Potter marathon, are we going to do Lord of the Rings, which that usually sends my kids into orbit?" Trying to find ways that we can connect after eating, "Are we going to play football or am I going to watch them play football?" By just finding things that we can do to connect together that don't per se disconnect us more, because I think it's very easy in our culture to be around other humans but be so disconnected like people that are on their phones constantly. And I'm certainly not perfect. I'm not by any means am I suggesting that, but I really try on holidays to be very connected and very present. And that to me is something I'm much more cognizant of now than maybe I was 10 years ago with my kids.

Melanie Avalon: Have you ever used one of those phone jail things?

Cynthia Thurlow: Not per se, although the other day, interestingly enough, my 15-year-old who is my more challenging child I will say, came home from some team practice. I know his blood sugar was low because he was hangry, he was just really grumpy. I had asked him to help take the dogs out and I got a rash of reaction to that. And because he was so disrespectful, I just said, "Well, I have your phone, and so I hid his phone for two days." So yes, we do have phone jail but said child is pretty clever and so he found his phone in the midst of phone jail and took it. And then he got another day added on to not having a phone. So, yes, we do Institute phone jail but not per se at the table. Usually, phone jail is when an infraction has been incurred and I'm trying to think of what will hurt him the most, [laughter] what is going to be the most unpleasant punishment I can give him. I'll just take your phone, and he feels like he's lost an appendage.

Melanie Avalon: I was going to talk about one other thing, but instead I'll save it for next week. And instead, I have to comment on the phone. When I was driving to dinner--Has your phone SIM card ever decided it's not there? Like your phone is like "can't find SIM card?"

Cynthia Thurlow: No.

Melanie Avalon: Oh, my goodness. It's crazy. Basically, your phone loses all capability, it can't be a phone, it can't make calls, it can't find the internet, and I was driving and I just realized how dependent we are on our phones because I was all dressed up and had all my stuff. And I was halfway to Midtown Atlanta. And my phone was not getting the internet. And I was like, "I don't know how to find this hotel." I don't know how to get there [laughs]. I was like what am I going to do? Pull off to a gas station and be like, how do I get to [laughs] Four Seasons, it was crazy, it made me realize just how reliant we are and then I just felt so useless that I was not going to be able to navigate, somewhere where I had gone before multiple times.

Cynthia Thurlow: I will just interject that. My mom lives in a rural part of Maryland on a beautiful lake and when I was coming back most recently, the way that I come from Western Maryland to get back to Virginia, I have to go through West Virginia for a brief scooch amount of time. Well, I went from having ways to having no ways, and then not knowing where I was because I had only gone this route once before. And at one point, I was driving for an hour with no ways, no Wi-Fi, no nothing.

Melanie Avalon: Did you feel naked? I felt so naked. "Oh, I felt naked."

Cynthia Thurlow: Yeah, I was like contemplating how do I find a police station and talk to them about the fact that I didn't think to print out directions because why would I have needed them? You start to realize how dependent we are on technology for sure.

Melanie Avalon: It's the craziest feeling and I was like, "Oh, this is what it was like back in the day." I bet people were a lot better with keeping appointments. Because if you don't show up, I was like "They're going to think I'm dead."

Cynthia Thurlow: No, I was explaining to my kids, we used to have MapQuest or we used to have these little Garmin's in our cars, and you would update them periodically, and my kids were like, what? And I was like, "Yes, you had to print things out or write them out." I was like, "That's how old school mom and dad are?

Melanie Avalon: When I was growing up had to print out from MapQuest. So good times.

Cynthia Thurlow: I'm glad to know you recall MapQuest.

Melanie Avalon: I was right on the cusp.

Cynthia Thurlow: Yeah. We represent many generations on this podcast.

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In fact, I even got robbed last year and I went from crying with stress and anxiety to taking some Feals and laughing. I said to my mom, “Mom, see how effective this is.” Due to all of its health benefits, we knew we wanted to partner with a CBD company for the podcast, but I have very stringent criteria. You guys know this. So many brands approached us and I kept just saying, “No,” because nothing fit all of my criteria. I wanted CBD oil that was full spectrum, tested for purity, organic, made with MCT oil as the carrier, and that I actually experience benefits from. That's a pretty tall order to fill. We said no to a lot of brands and then Feals came along and it was meant to be. I personally tried it out and started seeing massive effects on my sleep and stress. Feals is so easy to take. You can just put a few drops under your tongue and you'll feel the difference within minutes. I truly do feel it within minutes. 

Of course, it is important to remember that CBD works differently for everybody based on your own unique cannabinoid system. You might need to work to find your perfect dose. Experiment over the course of a week or so, and you may find that you need more or less depending on the effects that you're looking for. I'm also super grateful because they have an incredible offer for our audience. You can start feeling better with Feals. Become a member today by going to feals.com/ifpodcast and you'll get 50% off your first order with free shipping. That's feals.com/ifpodcast to become a member and get 50% automatically taken off for your first order with free shipping, feals.com/ifpodcast. When you get that offer, you'll be joining the Feals community and you'll get Feals delivered directly to your doorstep every month. You'll save money on every order. Of course, you can pause or cancel anytime. So, definitely try it out for the first month with our code for 50% off and see how it works for you. We'll put all this information in the show notes. All right now back to the show.

Melanie Avalon: Would you like to jump into everything for today?

Cynthia Thurlow: Absolutely.

Melanie Avalon: To start things off, we have some questions actually four questions that we can do rapid fire and they are from Casey. The subject is "Liquid chlorophyll during the fast, window flexibility, anti-inflammatory foods." And Casey says, "I have a few questions shared here." Number one, can I consume liquid chlorophyll in my water while in a fasted state or is this a no, no?"

Cynthia Thurlow: Yeah, well, I mean it's a plant. I think it depends on how it's processed because chlorophyll does not taste good and most chlorophyll that I have used with patients has some sugar, dextrose, etc., in it to make it palatable. In most instances, if you're looking at an ingredient list, it very likely has sweeteners in it and therefore I would not recommend that for a clean fast. Do you have an opinion?

Melanie Avalon: Yeah, especially after interviewing. I know you are friends with Teri Cochrane, she's wonderful. She wrote a book called, is it Wildatarian?

Cynthia Thurlow: Wildatarian? Yep.

Melanie Avalon:  I had her on The Melanie Avalon Biohacking Podcast. You've probably had her on your show as well, I'm guessing?

Cynthia Thurlow: I have, twice.

Melanie Avalon: Yes. She has fascinating thoughts on chlorophyll supplementation. I searched high and low to find a chlorophyll-- like a liquid chlorophyll supplement that didn't have lot of additives. The closest I could find was, it's mostly pure chlorophyll but has glycerin. It doesn't taste sweet. It tastes very grassy actually. But to be on the safe side, I would always just kind of have it to open my window. The chlorophyll itself is not a problem. But like Cynthia said, it's hard to find-- maybe I should make a chlorophyll. "Oh, my goodness." Okay, friends, stay tuned. I do think it's really wonderful. I would err on the side of keeping it in your eating window unless you can find a pure version, which, good luck.

Cynthia Thurlow: It's hard to find and it doesn't taste good. That's actually why oftentimes it is sweetened. I oftentimes will recommend chlorophyll for constipation.

Melanie Avalon: Hmm, nice. Teri recommends it for actually iron levels.

Cynthia Thurlow: Yes, I love Teri. I've had her on the podcast twice. And she always brings such a unique lens to looking at health and wellness, really a unique lens, like the Cochrane Method is her trademarked method and I've learned so much through her.

Melanie Avalon: She's really wonderful. Because she's the one who talks about the amyloid formation in conventional agriculture. I bring this up every time I interview somebody in the-- I don't know what words to use, I just brought it up the other day, interviewing the founders of regenerative pastures, which is kind of like a ButcherBox system, but they're US based only and they have a lot of really amazing options. But actually, that interview was amazing, but anytime I've interviewed somebody where we're talking about like conventional agriculture versus regenerative and holistic, I bring up Teri's theory, which basically is that the stress levels of the raising conditions create these truncated proteins and conventional meat that has a very inflammatory potential, which nobody else is talking about. So, I find that very cool.

Cynthia Thurlow: Yeah, and she's not a big fan of chicken and a few other things, but chicken is, I think the basis of a lot of people's diets, and by no means am I telling everyone to panic and stop eating chicken. But just to give it some pause and think that has a lot to do with her desire to encourage people to eat more wildatarian proteins, she certainly has had a huge influence on us. We got very creative during the pandemic.

Melanie Avalon: She's amazing. Okay, so much for rapid fire. Casey's, second question, she has some questions about supplements taken in the fasted state or during the eating window. We can just go through these, D3, B12, iron, so D3?

Cynthia Thurlow: Fat-soluble vitamins, vitamins A, D, E, and K, I generally recommend that you take with a meal so that they can slow the absorption, B12 provided that it's clean. That to me is benign. Iron, I generally like people to take with food for a variety of reasons. But I understand why people ask these questions because they are trying to simplify their lives, but I would say iron and D3 taken in a fed state, B12 or B vitamins I think are fine provided that they're clean taken in a non-fed state. What do you think?

Melanie Avalon: Agreed, the only caveat I would provide B12 similar to chlorophyll, it is water soluble, so it can be taken completely fasted but it can also be hard to find versions without the additives, they're usually always flavored, and also with B12, it can be really important, especially given your MTHFR status to get a properly methylated form, so Methylcobalamin version. And then my iron caveat would be-- and I struggle with iron regulation, really bad, I just don't seem to make ferritin, I do but there's just some issue there with my conversion, I think. I am very in tune with iron supplementation. I personally will use desiccated spleen as well as kidney which has some iron, I use ancestral supplements, I do have a code for them. If you go to melanieavalon.com/ancestral, the code AVALON10 will get you 10% off. I take their kidney every night, I take their spleen a few times a week and I take that with food. I don't take the spleen every day because I found-- researched this and I've talked with my hematologist about it. If you take iron supplements constantly trying to up your iron level, your iron actually has an iron regulation system where it downregulates its absorption if you're taking in a lot consistently. On the contrary, if you're not taking a lot, it will upregulate its iron absorption. It can be nice to do a punctuated approach.

Another option is chelated Iron because iron can be very constipating. I love Elle Russ-- I'm actually having her on my show for the third time coming up soon and I was just recently on her show The Elle Russ Show. She is very in tune with iron supplementation because it can really relate to thyroid issues. And she's a big fan of Chelated Iron by Bluebonnet and that has to be taken on an empty stomach. The reviews for that are very, very positive for people saying they are able to raise their iron and don't get constipated. So, that's another option, but that would be on an empty stomach.

Cynthia Thurlow: Yeah, the Chelated Iron is really key. I think for many years I was on Chelated Iron and there's nothing worse than being put on iron. And then if you're not constipated, then all of a sudden you can't go to the bathroom. So, Chelated Iron tends to be much easier on the gut. And I would agree with you that anemia in general and low ferritin levels, low iron levels can be very confounding. And it's not at all uncommon for women really at any stage of life to have issues surrounding this, so a commonly recommended supplement.

Melanie Avalon: Yeah, the iron issues are one of the banes of my existence? I'm really excited actually because I'm going to be interviewing Morley Robbins for his book, Cu-RE Your Fatigue, The Root Cause and How To Fix it On Your Own. And apparently, it's mostly about iron regulation. I'm excited to see what I learn about that.

Cynthia Thurlow: Yeah, it's interesting, your podcast about glutathione came out today. And I was like, "Oh," I'm knee-deep in podcast prep for two podcasts next week. But I was like, I really need to listen to that.

Melanie Avalon: Oh, it's so good. I was on the fence about glutathione IVs and glutathione pushes. Now I'm fairly convinced they're a waste. It's just in and out of your body and it doesn't even get absorbed really. I don't know if he's a doctor, I think he's just a researcher and a pharmacist, not just? But I think he's a researcher and a pharmacist. He wrote a book called The Glutathione Revolution. He does have his own proprietary topical glutathione where they have studies showing how it is absorbed in the half-life in the body. I've been using that every single day and night since reading the book and interviewing him, I'm sold. I think glutathione is so important, supporting it naturally, and then if you supplement using his version, I feel like I'm just giving all the codes. But his version that I've been using is melanieavalon.com/auro A-U-R-O is his brand, and then the code MELANIEAVALON should get you a discount.

Cynthia Thurlow: Yeah, it's interesting because Teri Cochrane is not a fan of IV pushes or IV glutathione drips. As we keep plugging Teri Cochrane that's definitely really aligned with my conversations I've had with her. But I'll definitely have to dive into that podcast.

Melanie Avalon: Let me know what you think. I think I wanted to believe it, because, you want to think, "Oh, I can get some glutathione IVs or pushes and do some good," but it's really like I said, in and out. And then after reading it, I reached out to my friend James Clement, he wrote a book called The Switch, and he's a dear friend. And I really, really respect him. And I really feel like I can always get a very unbiased perspective because he does have a book, but he's not selling anything. He runs a lab that studies longevity. I asked him and he's like, yeah, there's no point in taking glutathione, it was when I was actually feeling really sick. And I was texting him. I was like, "What do I do? Try to get NAD." I was like, "I'm going to go get glutathione" and he's like, "Don't get the glutathione, it's not going to help." So, tangents.

Okay, and then another question from Casey, she said, "She's considering a window of 12 to 8 o'clock, but she feels on a Saturday or weekend that she might need more flexibility due to long runs or social engagements." So you have recommendations on timing to make the weekends work?

Cynthia Thurlow: One of the key aspects of intermittent fasting is flexibility. I'd really encourage you to experiment, maybe you're going to have a wider feeding window on a weekend, maybe you'll have a shorter fasting window on a weekend. I think that the key is really kind of leaning into what makes the most sense for you. I know that pre-pandemic I definitely was much more flexible in the weekends, because we were oftentimes going out or had events, and I couldn't per se time when I was eating or when I wasn't eating, it was oftentimes dependent on other people's schedules. I would say experiment to see what feels good, maybe if you're doing longer runs, you're going to want to break your fast earlier. Maybe if you're going out to dinner, you are going to have a wider feeding window. And that's completely fine and I do encourage people to change up what they're doing. Our bodies get very accustomed to eating the same foods, having the same fasting windows. And so, I do like variety. How about you? Do you have any different ways of doing things on the weekend?

Melanie Avalon: Well, first of all, I love your answer. And that's the answer is basically going to suggest which is just-- I think it's actually-- Especially if you have a regimented window during the week, it's a great time to have some flexibility, and actually, you said change things up, keep your body guessing. Well, I do a completely different window. If I was doing her window, I probably would adjust it a little bit where I might just open it a little bit later and keep it open later. Assuming that you're having social engagements at night dinners, things like that. For me personally, I really honestly do the same window every single night. I don't need to adjust because it literally fits in almost every situation.

The only time it wouldn't fit would be if I had to go to an early dinner. And then honestly, I probably just wouldn't eat. If there's one thing I won't do, I don't eat if I'm not hungry, I don't eat just to be social, I don't enjoy it. So, if that's the case, I usually would just drink and then eat later which interestingly, another tangent, this might be controversial, but they'll often say to have alcohol with food to slow the absorption and have a better effect on your body. I find the only time I'm really drinking with food is when I am having dinner out because normally, I drink before eating. And I find that I do a lot better that way drinking before because I feel like my body processes the alcohol completely and then it's not impeding or competing with the dinner. And I find when I have wine with food, I feel like the alcohol lasts longer in my system. So, just a random thought.

Cynthia Thurlow: Yeah, I'm definitely one of those people that I had to drink with food because if I didn't, I would feel the effects pretty strongly. [laughs] I would be the person who would be like, "Uh-oh," I don't feel so great.

Melanie Avalon: Actually, maybe that's why I like it more not because I like feeling crazy, I can drink less and have the drinking experience compared to if I'm having it with food, I would maybe drink more.

Cynthia Thurlow: You know, what's interesting is that I always assumed that because I was the type of person, I could never really drink a lot. What's unique about my body, I don't make enough alcohol dehydrogenase to break this down properly or are my detoxification pathways just not optimized? I mean those are the things I used to spend time thinking about. [laughs]

Melanie Avalon: I've done my genetic data and one of the systems that I ran it through, I know I've said this on the podcast before, but I don't know if I've said it when I was with you. It basically looked at your, "Oh, I think it was the SelfDecode report. It was the food one," and it showed you like all these different food options, like carbs, I don't know, there was like four food-related things, and there was alcohol, I was bad with everything food related and great with alcohol. Alcohol was like green and then everything else food related was like red, red, red. [laughs]

Cynthia Thurlow: Well, it's interesting because I did do genetic testing over the summer with Kristina Hess and that's an area of nutrigenomics, that's her area of expertise. Things that were consistent, and validating were things like, "Do you like lean meat or fatty meat?" I was like, "Oh, lean meat all the way. I don't feel good when I eat fatty meat." And we were going through the report and she was like, "I can see where that is, I can see where you're very athletic, I can see that you're someone that actually would tolerate a little bit of dairy, you can actually tolerate a little bit of alcohol." And I was like, "That's interesting," because it hasn't been my own experience. But we can't consider the fact that or we need to consider why bio-individuality is such an important aspect of whether we're leading into this next question talking about inflammatory foods. For each one of us that could look very different and I know I don't think I ever perceived the foods I no longer consume now were bothersome even 15 or 20 years ago. And so, just understanding that there's the genetics piece plus exposure piece, and they can all play a role in how we feel when we eat certain foods.

Melanie Avalon: I think that's so key and speaking to that it's so interesting when you do pay more attention and "Clean up what you're eating," how you do notice, "Well, I don't really eat foods that bother me now." But if I were too, I really notice and I just look back at my old self and I think about everything that I was eating and how I didn't even notice because I think it was an overall systemic inflammation. So, you didn't really pick up on any one signal from food. But yeah, so Casey's last question which you hinted at. She says, "What are some of your top anti-inflammatory foods? What are the foods you'd recommend avoiding that are most inflammatory?"

Cynthia Thurlow: When I think about top anti-inflammatory foods, I really think about phytonutrient dense foods. When you hear the term eat the rainbow, I think about green leafy vegetables, I think about berries, especially blueberries, raspberries, blackberries. I think a great deal about medicinal mushrooms, and no I'm not talking about mushrooms that are psychedelic. I think about curcumin which is a component of turmeric. I think a great deal about polyphenols that you get in green tea and bitter teas and black coffee, preferably mold-free. The most inflammatory foods in my estimation are seed oils and highly processed hyperpalatable foods, gluten, dairy, in particular people that are susceptible to that, sometimes grains, processed sugars, alcohol, soy, so it really depends, just like Melanie was saying she feels differently when she has alcohol on an empty stomach versus in a fed state. Bio-individuality but seed oils are the most inflammatory foods worth eliminating if you do nothing else. Read labels, ask when you go to restaurants, I think seed oils down to a cellular level the most damaging food like substances that most of us consume unknowingly in many ways. How about you?

Melanie Avalon: Yeah, we have very similar lists. So actually, my big one for anti-inflammatory isn't so much a specific food as it is an approach to the amino acid profiles of foods. In particular, because there are nine essential amino acids and some of those are more growth-promoting and can be inflammatory in high amounts, particularly things like methionine, which is really high in muscle meats, compared to "more anti-inflammatory amino acids," things like glycine. So, fish, for example, tends to be a more and I'm using quotes because inflammation itself is so complicated and nuanced and in a way, it's hard to really deconstruct what is inflammatory and what's anti-inflammatory, but in general, the amino acid profile of fish tends to be a "more anti-inflammatory amino acid profile" than something like muscle meat and then the amino acid profile of more gelatinous cuts of red meat tend to be more anti-inflammatory. That is actually a large reason that I make shellfish and fish basically the foundation of my protein, it's the reason I eat so many scallops because I read this one study that looked at the inflammatory potential, I think it looked at like liver enzymes or the effect on the liver in particular and it looked at chicken, cod which is fish, scallops and then one more, I'll have to find the study and put this in the show notes. But the effect of scallops, like the anti-inflammatory potential was insane. After I read that I'm eating scallops all the time.

Cynthia Thurlow: You want to know, it's one of the few foods my husband hates. So like, "I can only really eat scallops when I'm in restaurants because he dislikes them that much, but I actually really enjoy them."

Melanie Avalon: Oh, I love those scallops as you guys know. Yeah, having scallops, for example, would be a pretty anti-inflammatory protein. And then it's not just the amino acids as a benefit of fish, also the omega-3, omega-6 ratio. And this is another thing where it's not so much take omega-3 because it's anti-inflammatory, I think what's more important is the ratio of omega-3 to omega-6 because we need both. And we just want the ratio to be more in favor of the omega-3 side. I've seen different amounts when they say hunter-gatherers ate omega-3 to omega-6 ratio of between 1:1 to I think between 4:1, which, sorry omega-3 to omega-6, yes, 4:1, or wait it'd be another way around? Probably the other way around. In any case, today, the ratio tends to be I think it can be like 20 or 30:1, it's crazy.

And again, a lot of people will go the route of like, "Oh, well, high dose the fish oil, eat all the salmon." I think it's more about the ratio, I don't think we necessarily need a huge amount of these omega-3s and omega-6s in our diets, but we want that ratio to be more ant-inflammatory than inflammatory. Although if you want a really nuanced conversation on this, which is going to add a lot of caveats, listen to my interview with Chris Masterjohn, because we dive deep into this and he actually has a much more complicated view, which contradicts a little bit about what I said, but it still stands that the omega-3 to omega-6 ratio I think is important.

And then on top of that some things that Cynthia mentioned, a lot of spices can be really anti-inflammatory. She mentioned curcumin that's found in turmeric, I eat so much turmeric every single night. I eat a lot of ginger.

Cynthia Thurlow: I love ginger.

Melanie Avalon: I love ginger, I love turmeric and ginger. They are the two "spices" because I know ginger is a root. I just gravitate towards them like none other and then they always come up in the list of the go-to anti-inflammatory spices. I like to high dose those, ate a lot of that. Everybody knows I went through my pineapple phase. Pineapple can be really anti-inflammatory because of the bromelain, which is a proteolytic enzyme that breaks down proteins, kind of like serrapeptase except serrapeptase, you're taking in a fasted state and pineapple is a food and can help with digesting your food. The main reason I want to get back to pineapple and the reason I haven't is for some reason intuitively, it just feels too sweet to me now, but when I was eating that the reductions in inflammations I just saw personally in myself were amazing. And then for the inflammatory side of things, trans fats, yes, they've been banned, but they are still there, seed oils, that's what I had written down for sure like Cynthia was saying I do think that is huge, especially the processed ones, the refined seed oils, and they're just rampant. I think Cate Shanahan, her book, The Fatburn Fix talks a lot about this, and there's like the three S's, canola, corn, cottonseed, safflower, soy, sesame?

Cynthia Thurlow: Sunflower.

Melanie Avalon: Sunflower. Yeah, so definitely looking for those. Gluten, I think can be very inflammatory for a lot of people. Those were the three main ones I wrote down and then just in general, I think the most inflammatory thing, well "processed foods," just processed foods, and then just eating too much like the energy toxicity of overindulging can have a very inflammatory effect compared to a calorie-restricted diet or fasting, which ultimately tends to create calorie restriction or allows for that fasting time can be anti-inflammatory. But the eating process is inflammatory just by its nature.

Cynthia Thurlow: It's all good.

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Shall we go on to Bruce's question?

Cynthia Thurlow: Yes, this is the subject, "Thanks for all you do. I recently listened to all of the episodes on your podcast, and I would like to thank both of you for your dedicated work. I'm wondering if you've seen anything on sauna sessions and fasting. I have a sauna that I built a few years ago and use it four times a week. I have recently started using the red lights that are part of the lighting system that came with the heater control package because Melanie saying red lights were beneficial. Love Bruce." I cannot think of a more Melaniesque appropriate question."

Melanie Avalon: Bruce, thank you so much for your question. I do love the red lights, so I'm glad you're on that board as well as the sauna. I googled sauna and fasting and I didn't really find any studies per se. But I can speak to my personal experience and I found a very wonderful blog post written by Siim Land who I've had on my show twice.

Cynthia Thurlow: Me too, he's awesome.

Melanie Avalon: He's wonderful. Although I was thinking, I feel like he hasn't been posting. I feel like I haven't seen much from him recently.

Cynthia Thurlow: Yeah, he's been quieter. I don't know, he might be writing a book. He's like a proliferative writer.

Melanie Avalon: He's just so smart.

Cynthia Thurlow: Mm-hmm and he doesn't have-- one of those things for me, I really am oftentimes fascinated/humbled when people that don't have traditional research or medical training are just able to grasp such complicated concepts, much like you Melanie, you can grasp such complicated subjects and really understand it at a level that even for myself, sometimes I'm like, "Wow, I had never thought about that." So, he's one of those young protegees of the science community.

Melanie Avalon: Well, first of all, thank you for saying that. And yeah, he's younger than me.

Cynthia Thurlow: I guess he's like, 25. [laughs] He's a young buck.

Melanie Avalon: I'm thinking maybe because he is so young maybe he had some life development career-wise.

Cynthia Thurlow: No, I think he's just smart and curious snd I think that has served him well.

Melanie Avalon: Yeah. I know he's amazing. I found a blog post by him called Why Combine Sauna and Fasting. I'll put a link to that in the show notes. But I will give you the takeaways from that blog post. This is all the work of Siim Land, not myself. But he makes the case that both sauna and fasting have a lot of similar benefits as far as anti-aging, longevity, and supporting the immune system. And sauna has some benefits that fasting does not automatically provide. For example, the cardiovascular workout equivalent of a sauna session, you're not going to get that from fasting. And then on the flipside, I guess you could say there are things that fasting would provide that sauna wouldn't necessarily. 

But he says that they work really well symbiotically for something that, I would have never come up with this and I don't think I would have ever come up with this. But he talks about the importance of autophagy in both fasting and sauna, so both sauna sessions and fasting instigate autophagy, which is basically a cellular cleanup process in the body. It's really linked to longevity, anti-aging, disease prevention, so many things. What's interesting is one of the main benefits of sauna comes from heat shock proteins that are activated when you do a sauna session. And there are some studies on heat shock proteins in rodents and they found that the autophagy process is actually required to experience the benefit from the heat shock proteins. And the autophagy in part possibly mitigates some of the actual stress or the detrimental effects of heat shock proteins. It's possible that by really ramping up your autophagy, which would happen with a fasted state that you will get more benefits from the sauna, and you'll get a more-- to use that word anti-inflammatory response, you're going to get the benefits either way, and it's not something to be worried about. But basically, the fasting during the sauna session, he said, it's basically like better quality control when your body is doing that cleanup process and inactivation with the heat shock proteins, keeping the healthy cells and getting rid of the negative cells.

And then something else, I actually did think about this, he mentioned this, but I think I would have thought about this too. He talks about how both fasting and sauna increase human growth hormone. And he thinks doing sauna while fasting can further increase that human growth hormone and mitigate any potential catabolic effects of fasting. The reason I think I would have thought about that was because I interviewed Wendy Myers recently, she pointed out something in her book that blew my mind. I read it. I don't know if I mentioned this on the show already. I read it, I was like, "Oh, that can't be." I was like because somebody would have told me that, I actually didn't believe it. And then I went to find a study and it's true. Did you know, in order to release human growth hormone from exercise, it's from the heat created from the exercise, like it requires heat.

Cynthia Thurlow: Interesting. I guess that's why it's important to sweat and raise that core temperature.

Melanie Avalon: Yeah, that blew my mind. I was like, "No, surely exercise releases human growth hormone by some other mechanism." But no, it actually requires heat, if you're like working out, and you never raise your core body temperature, you actually might not be getting some of the benefits.

Cynthia Thurlow: It's interesting because I do Pilates every week and this morning it was a different type format of Pilates, and it's not my favorite. And I was laughing with the instructor who I love. I just take her classes because she really challenges me. And I was laughing and saying, "Okay, it takes me about five minutes of doing Pilates, we're lifting or whatever I'm doing to warm up enough that I take off whatever shirt I have on." And I was saying to her what we were doing this morning was so much more intense that within like two minutes I was sweating. And so, I think it makes sense and you have to exert yourself hard enough because we're really looking for some degree of hormesis. We want a beneficial stressor to the body, so that would make sense although I don't think I've per se thought about it that way before.

Melanie Avalon: Yeah, it really blew my mind. But yeah, that word hormesis. I think basically the case that Siim Land makes with a sauna is that you will get a more beneficial hormetic response from sauna use if you're fasting during it. And then I just know for me personally that you could not pay me to go in a sauna with food in me, that experience feels very unpleasant. Because there's something about like the detox and the sweating and letting it all out like to be digesting food and to have all of that and yet at the same time would just feel like "Oof," it would feel " Oof." It'd just not feel good. I do have a sauna recommendation if people would like a recommendation. I personally use the Sunlighten Solo unit every single night of my life. I cannot even express my obsession with this creation. I would love to have a cabin unit which Sunlighten also makes cabin units. But I live in an apartment that's not going to happen and their solo unit is this really cool contraption that you actually lay down inside of. It's kind of like, I don't want to say a coffin, it's a dome.

Cynthia Thurlow: It does not look like a coffin. [laughs]

Melanie Avalon: It does not, it looks like, I don't even know how to describe it. And it lights up, it has chromotherapy lights. And what's really wonderful about it, especially for me is your head is outside of it. I attach-- I've come up with this whole-- You can get one of those bendy arms that holds your phone and I attach that too because I put the solo unit on top of a twin frame, metal frame from Amazon that I got, so I can put a link to that in the show notes. I attach an arm and then it holds my phone over me so I can lay in there, my head is out of it, and I can read my books, and do my research, and do emails and it's just the most wonderful experience. They also have their products tested for EMF which is amazing. I recommend that solo unit. I also recommend obviously they're cabin units if you do have the space for that as well. If you tell them I sent you, they will give you a really good discount. That's at Sunlighten. But, Cynthia, do you have a sauna?

Cynthia Thurlow: We do not yet and that has something to do with the fact that we are putting a pool in next year and we're going to create an exterior structure. And I am envisioning that the exterior structure will have our infrared sauna in it, as opposed to it would have to reside in our garage. Even though the Sunlighten people have assured me it's completely fine. The area of the country I live in is very humid in the summer. And the thought of [laughs] being in a steaming garage with an infrared sauna is not really of interest to me. Right now, I have a sauna blanket. And yes, I'm working with the fact this is a temporary solution by HigherDOSE and so it's a sauna blanket that you get inside of and you sweat like crazy. And then I get on my PEMF mat, and I'm just so happy, I cannot tell you how much I enjoy the PEMF mat, I fall asleep on it, it's so relaxing, there are different settings, I have no affiliation with HigherDOSE, I just recommend that mat to everyone. But if you are space-constrained, Sunlighten makes apartment and small space-appropriate options as well as HigherDOSE, coming from a very large house that we had in Northern Virginia with a very large basement to a slightly smaller house with no basement has meant that we've had to get very creative. So, when that exterior structure is created, I'm excited because it's going to have like a little gym area inside that I can work out in.

Melanie Avalon: It's very exciting. Yeah, I can't wait for you to get the experience that you were sharing about just how good PEMF makes you feel. That's the way I feel after my sauna session each night.

Cynthia Thurlow: And I think it's important to find things that make you feel good. For me, I fell asleep on it every night this week, and I was like, Okay, "I cannot fall asleep on it because and I can't fall asleep in my normal time." So, now I have to do shorter episodes because you can change the settings and certain settings are impacting you more for relaxation and pre-sleep mode versus stimulating. And there's nothing better than lying on this warm mat. It's just glorious. Makes me feel so good.

Melanie Avalon: It's amazing. All right, shall we answer one more question?

Cynthia Thurlow: Sure.

Melanie Avalon: We have one last question; this is from Justine. And Justine says, "Hi guys, love the podcast, I've been listening at work, and I feel like I've learned a lot already. I'm relatively new to intermittent fasting, but I've had a good experience and results so far. You've talked previously about the science you feel when you are in ketosis, metallic taste in the mouth increased or different energy. Could you go over the signs to look for as a new intermittent faster, I am anxiously awaiting a sign that I am in ketosis but I'm not sure what to look for. Thanks, from Ottawa, Canada."

Cynthia Thurlow: Well, Justine, welcome to the intermittent fasting world. Typically, when patients or clients are asking these kinds of questions, we're really looking for signs of metabolic flexibility if we're able to effectively utilize stored fats or glucose or create ketones. And so, I think about being able to go longer in between meals. If you can go four to five hours in between meals and have good amounts of energy, you're not having energy slumps after eating, you are able to regulate your weight, part of metabolic flexibility is having the ability to lose weight more effectively. But I think about the brain cognition piece being a big one, if you're able to effectively create ketones and specific ones can diffuse across the blood-brain barrier. So, mental clarity, energy sustained from meal to meal, not getting hangry, effectively being able to lose weight. Those are probably the big ones that I think about what about you, Melanie?

Melanie Avalon: Yeah, so those are really good for the signs, I guess the only thing I would add is as far as if you actually wanted to confirm or measure and we've talked about this at length multiple times on the show, but just to briefly go through it, you can measure ketones, there are caveats and nuances to all of it. If you're brand new to intermittent fasting, urine keto strips can be great because you will likely see that shift when you actually start generating ketones and a large portion of those ketones. Your body doesn't know how to use them in the beginning, so it like gets rid of a lot of them through your urine. The issue with urine sticks ongoing is that as your body becomes more used to using ketones, you don't excrete as many through the urine. It's not a really good long-term way to monitor ketosis or you can also monitor blood and breath. Monitoring your blood, there also can be a little bit of that effect where you might see more in the beginning and then as you become better at using it, you might see lower levels on your blood ketone meter. That said, you should always see them, you're not going to be in ketosis and not see ketones on your blood ketone meter. So, that can be a good thing to monitor. I really like Keto-Mojo's brand of their ketone meter. And then you can also measure the breath. So, the breath is also a byproduct of when we burn ketones. Interestingly, Dominic D'Agostino has talked about this, he's made the case that breath ketones are likely more a product of when you're actually burning fat compared to like dietary fat, which I thought was pretty cool just because of the whole metabolic process and what would create those breath ketones, so you can get a Biosense meter for that if you want to measure breath ketones, and I do have a code. You can actually join my Facebook group has a long name, Lumen, Biosense & CGMs: Carbs, Fat, Ketones & Blood Sugar and then (Melanie Avalon) basically if you type in Melanie Avalon Facebook Group, I have three groups and this one will come up. You can get $20 off of Biosense. If you go to melanieavalon.com/biosense and use the coupon AVALON20. What are your thoughts? Cynthia on measuring all of these different ketone options?

Cynthia Thurlow: Yeah, I think they're nice. Certainly, Dr. Anna Cabeca talks a lot about urine ketones and when you're new to being in ketosis that can be valuable. But those kinds of things add up. That's why, I typically start with-- these are signs and then you can get further validation. I do like Keto-Mojo, I really, really enjoy the owners. I think that they're delightful and they're really trying to help change the narrative especially about insulin resistance and diabetes, and just making people more aware of the net impact of food choices and lifestyle on our blood sugar. I think those are certainly really great options. I'm not as familiar with Biosense, but obviously I know that you've done your due diligence, but I think the devices to me are secondary to actually getting to a point where you start recognizing the signs that demonstrate that you're becoming more metabolically flexible. And just remember, it's a very small percentage of the population here in the United States, right now, it's about 7% to 8% are metabolically flexible. So, really important for everyone to lean into that.

Melanie Avalon: Yes, I agree, I think that's so important, it's a fine line. I just wish everybody could have the full knowledge of ketones before engaging with these devices so that they have the healthiest relationship with the device and what they're learning from it.

Cynthia Thurlow: I totally agree.

Melanie Avalon: Yeah, because you don't want it to be something that is a hurdle to something that you're doing that's good in your body because you feel like you're not creating enough ketones. I think it can just become an issue. I actually never measure my ketones ever. And we actually have a question that we didn't get to today, maybe we'll get to it next week, about our diets and if we're getting into ketosis or not, and I'll say this again when I answer that question, but I might not be, I don't know, I might not be getting into ketosis, you can burn fat without getting into ketosis. Surprise, well, this has been absolutely wonderful. So, a few things for listeners, before we go, if you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. You can get all the stuff that we like at ifpodcast.com/stuffwelike although I have it on my to-do list, I really need to get that page updated. And you can follow us on Instagram. We are @ifpodcast. I am @melanieavalon, Cynthia is @cynthia_thurlow_ and I think that is all the things. Anything from you before we go?

Cynthia Thurlow: No. I'm just looking forward to our next recording and I promise that our first question won't take quite so long.

Melanie Avalon: Yeah, well, it was lots of questions.

Cynthia Thurlow: it was, very nuanced, but all good information that I think is applicable to most people that are listening.

Melanie Avalon: Yep. All right, well, this has been absolutely wonderful and I will talk to you next week.

Cynthia Thurlow: Sounds good.

Melanie Avalon: Bye.

Thank you so much for listening to The Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team, administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and re-composed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Oct 09

Episode 286: Thyroid Regulation, Iodine, Fasting For Your Cycle, Insulin, Glucagon, High Protein Diets, Surgical Menopause, Prescription Medication, And More!

Intermittent Fasting

Welcome to Episode 286 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

BUTCHERBOX: Grass-Fed Beef, Organic Chicken, Heritage Pork, Wild-Caught Seafood: Nutrient-Rich, Raised Sustainably The Way Nature Intended, And Shipped Straight To Your Door! For A Limited Time Go To Butcherbox.com/ifpodcast And Get A 10 oz New York strip steaks and 8 oz of lobster claw and knuckle meat FREE in your first order!

BEAUTY AND THE BROTH: Support Your Health With Delicious USDA Organic Beauty & The Broth Bone Broth! It's Shelf Stable With No Preservatives, And No Salt Added. Choose Grass Fed, Grass Finished Beef, Or Free Range, Antibiotic And Hormone-Free Chicken, or Their NEW Organic Vegan Mushroom Broth Concentrate! The Concentrated Packets Are 8x Stronger Than Any Cup Of Broth: Simply Reconstitute With 8 Ounces Of Hot Water. They’re Convenient To Take Anywhere On The Go, Especially Travel! Go To melanieavalon.com/broth To Get 15% Off Any Order With The Code MelanieAvalon!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get A 10 Oz New York Strip Steaks And 8 Oz Of Lobster Claw And Knuckle Meat FREE In Your First Order!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

The Melanie Avalon Biohacking Podcast Episode #12 - Elle Russ

Ep. 129 – Middle Age, Menopause, and Mindset: How These Components Affect Your Thyroid Health with Elle Russ

Ep. 105 Thyroid Physiology and Chronic Illness – with Dr. Eric Balcavage

Ep. 166 How to Maintain a Healthier Thyroid: Interesting Thyroid Physiology Health & Preventative Care with Dr. Eric Balcavage

The Melanie Avalon Biohacking Podcast Episode #1 - Dr. Alan Christianson

Ep. 154 How to Normalize Your Thyroid Function: What You Can Do To Help Support Your Body with Dr. Alan Christianson

Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist, And Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

Text "AVALONX" To 877-861-8318 For A One Time 20% Off Code for avalonx.us

BEAUTY AND THE BROTH: Go To melanieavalon.com/broth To Get 15% Off Any Order With The Code MelanieAvalon!

Listener Q&A: Ashley - Struggling with consistency

Listener Q&A: Monica - 3rd time is a charm?

High dietary protein intake, reducing or eliciting insulin resistance?

Effects of high-protein diet on glycemic control, insulin resistance and blood pressure in type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials

Protein: metabolism and effect on blood glucose levels

Ep. 109 How To Transform Your Health With Diet And Exercise – With Dr. Ted Naiman

The Melanie Avalon Podcast Episode # 30 William Shewfelt And Ted Naiman

The Melanie Avalon Biohacking Podcast Episode #94 - Marty Kendall

Listener Q&A: Jessica - Menopause, HRT, etc

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 286 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time, and get ready for the Intermittent Fasting Podcast.

Hi friends, I'm about to tell you how to get two grass-fed, grass-finished 10-ounce New York strips and one-half pound of sustainable wild-caught lobster meat all for free? Yes, for free. We are huge fans around here of a company called ButcherBox. They deliver 100% grass-fed, grass-finished beef, free-range organic chicken, heritage-breed pork, that's really hard to find, by the way, and wild-caught sustainable and responsible seafood shipped directly to your door. When you become a member, you're joining a community focused on doing what's better for everyone. That includes caring about the lives of animals, the livelihoods of farmers, treating our planet with respect and enjoying deliciously better meals together.

There is a lot of confusion out there when it comes to transparency regarding raising practices, what is actually in our food, how animals are being treated. I did so much research on ButcherBox, you can actually check out my blog post all about it at melanieavalon.com/butcherbox. But I am so grateful for all of the information that I learned about their company. All of their beef is 100% grass fed and grass finished. That's really hard to find. They work personally with all the farmers to truly support the regenerative agriculture system. I also did an interview with Robb Wolf on my show, The Melanie Avalon Biohacking Podcast, all about the massive importance of supporting regenerative agriculture for the sustainability of not only ourselves but the planet. This is so important to me. I'll put a link to that in the show notes.

The value is incredible, the average cost is actually less than $6 per meal. And it's so easy. Everything ships directly to your door. I am a huge steak lover. Every time I go to a restaurant, I usually order the steak. Oh, my goodness, the ButcherBox steaks are amazing. And we are so excited because ButcherBox has an incredible offer just for our audience. You can get some of those steaks for free and lobster to go with it. You can go to butcherbox.com/ifpodcast and get two 10-ounce, grass-fed, grass-finished, New York strips and one-half pound of wild caught sustainably raised lobster meat all for free in your first box. Yes, completely free. That's butcherbox.com/ifpodcast and we'll put all this information in the show notes.

And one more thing before we jump in. Are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense, because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting. It's actually our skincare and makeup.

As it turns out, Europe has banned over eight thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disruptors, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup maybe playing a role in that.

Beyond weight gain and weight loss, these compounds have very detrimental effects on our health, and they affect the health of our future generations. That's because ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years. Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means, when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves.

That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so, you can truly feel good about what you put on. And friends, these products really, really work. They are incredible, they have Countertime for anti-aging, Countermatch for normal skin, Countercontrol for acne and oily prone, and Counterstart for sensitive. I use their overnight resurfacing peel and vitamin C serum every single night of my life. And their makeup is amazing. Check on my Instagram to see what it looks like. Tina Fey even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more.

You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20, to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well.

And lastly, if you're thinking of making Clean Beauty and Safe Skincare, a part of your future, like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20, to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show.

Hi everybody and welcome, this is episode number 286, of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hey, Melanie, how are you?

Melanie Avalon: Good, how about you?

Cynthia Thurlow: We were just commiserating about this. But when your thyroid medication gets changed, it can sometimes be a little bit of a bumpy ride. So, I'm feeling I need to prop up my eyes with toothpicks today.

Melanie Avalon: I've been on the same bus that you've been on with trying all different forms of thyroid medication. It's just so complicated because there's so many opinions and there's so many options. And it can be hard to really find what works for you.

Cynthia Thurlow: Totally, I think if anyone that has an underactive thyroid that's listening, I know you understand [chuckles]. I know you understand, so I'm trying to just wait it out. My functional medicine doc is encouraging me to wait it out another week and get my labs checked. Goodness, I feel I need a power injection in the afternoon because I feel like I need a nap. And who has time for that every day?

Melanie Avalon: Well, I will say, this actually made me think about this. Sort of recently, I was in a period where I was feeling I needed a nap every day. And I just realized you know how you don't really notice when the negative things are gone? I just feel when I'm experiencing something negative once it actually goes away, I don't you may normally realize it. I just realized, "Oh, I haven't been needing a nap every day." I think the difference is, when I got sick a few weeks ago and started really high dosing the NMN and I stayed on the NMN every day at a higher dose. I don't need naps anymore. I think that's what it is, I don't know what else it would be. Although I have realized I feel a little bit more wired at night as well. So, I'm maybe I'm too high dosing. So, that's a benefit. I didn't used to be a nap person, and then I was and I'm not. How about you?

Cynthia Thurlow: Every once in a while, might need it but I generally, power through my day. And on a lot of levels, the fact that I consistently every single day, I'm this tired, the only variable that's changed is the thyroid medicine. And I knew this would happen because what typically happens is I get insomnia. And then, I have a crash in the afternoon. That has been a consistent pattern. Even though they've increased my T4, they lowered my T3. And my functional medicine doc said, and I quote, "You have the most interesting thyroid panel I've ever seen." And I said I don't want to be interesting I just want to be normal. I'm trusting the process. And he's absolutely brilliant and one of the smartest physicians I've ever met, so I am trusting in the process but in between, I will need naps in order to function.

Melanie Avalon: Do you think you'll increase your T3?

Cynthia Thurlow: He might. I think it's interesting, I'm supposed to have lab, he wanted labs drawn two weeks after I started the medication. So, I've already got that appointment set up, and I knew as soon as I started, I knew that there would be this bumpy-- this has been the pattern every single time they've changed my medications. In fact, I thought for a moment, because I keep all my old medicines just to describe to people, I'm not kidding, I really have been on 10 different prescriptions in the past two years. And it's a bag of thyroid medicine. And my husband was like, "What is that?" And I was like, "I don't know, it's a trophy. I'm keeping this for posterity's sake, I'm not sure." But to really demonstrate this is what people go through. And I'm a clinician and we still haven't gotten it right, so it goes on to just suggest that many people listening, are probably struggling with the same thing. So, that's why I wanted to share, to be transparent and say, "Yes, I'm a clinician. But yes, I'm still struggling to get the right combination of medications."

Melanie Avalon: I don't love that you're experiencing that. But [chuckles] I love it that's your approach. And yeah, some good resources for listeners. Have you interviewed Elle Russ?

Cynthia Thurlow: I have Elle and Eric Balcavage, Balcavage, sorry, I just mangled his last name, he's wonderful. He does a great Thyroid Thursday on Instagram. So does a lot of teaching. I think he's a great resource. And we both have had Alan Christenson on, but I would say Eric does a lot of didactic teaching as a clinician, which I love. And then Elle is all about empowerment, which is fantastic.

Melanie Avalon: Yeah. And Dr. Alan Christianson, who you just mentioned, it's funny, when I first met him, I was really struggling with my own thyroid panels. He is the nicest person ever because I literally just met him, and we've been vaguely emailing actually about intermittent fasting stuff. We were debating the literature on it. I guess at some point, my own thyroid issues came up and he was so nice. At one point, he was like, "Well, send me your labs to look at." I sent them to him, and he called me, he was like, "I have to talk to you about this [laughs] We have to get this fixed now." I was like, "Oh my goodness. You're the nicest person ever." He has a book called The Thyroid Reset Diet. He was actually my first episode of the The Melanie Avalon Biohacking Podcast.

Cynthia Thurlow: You what's funny, so fast facts. Alan was part of my Mastermind. When I joined it, and I recall the very first time I met him in person, I was sitting next to him at a lunch, and I was trying to be really cool. Because sometimes when you meet these people that you've been following them for years, and then you're socially around them. All I say to myself is, "Just be cool. He is a normal guy." And he is as nice as nice could be. I just think Midwesterners in general are just such nice, down to earth, human beings. And he really is as nice as he appears to be, and very quiet and introverted and I really enjoyed the time that I had with him, but I think he's a great resource.

Another funny thing to share with you is that the podcast team that I had at the time that I recorded a podcast with him about his new book about iodine, the podcast title was Intermittent Fasting and Thyroid Health, and I just about had a minor heart attack, because he's not a big fan of Intermittent Fasting. And I literally was like, "You cannot put that out. You cannot do that." And then, I had to explain the context. I was like, that is absolutely the worst title you could ever come up with.

Melanie Avalon: It's funny, the way I met him actually was-- I don't know if it was him or it was probably his publisher, or publicist, or somebody. They pitched him to come on this show. And it was for his metabolic reset diet. And literally at that time, he literally had a video on YouTube about-- it was basically deconstructing intermittent fasting. I wanted to engage with them. But Gin was not too excited about the idea. And so, that's why I started talking to him via email and started discussing the studies. And he actually took down that video, I think, after it because we talked about it some more and I think he realized there was a slightly more nuanced perspective on that specific content that he had created. And I just thought that was so impressive. But yeah, I know, I love his work. He has the thyroid reset diet, the adrenal reset diet. What's the book on iodine called?

Cynthia Thurlow: No.

Melanie Avalon: That's the thyroid reset diet.

Cynthia Thurlow: Yes.

Melanie Avalon: I'm still haunted by that. I still don't know what I think about it.

Cynthia Thurlow: I don't agree, politely I don't agree.

Melanie Avalon: I need to reread it, because it's interesting, because it's so contrary. It's not like it's slightly different than the popular idea. So basically, for listeners, a lot of people in the functional health world, and I guess nonfunctional as well, advocate needing more iodine to help thyroid and just health in general. And a majority of the book is about how iodine is actually the issue, and we actually need to be on a low-iodine diet. So, yeah, I don't know.

Cynthia Thurlow: I think it's important to entertain the possibility that there may be aspects to that argument that are applicable, but I don't necessarily agree but I don't have enough background, I'm not an iodine specialist, but I do ask my functional medicine friends and I would say iodine is a controversial issue because you have people like Brownstein, who is pro iodine, and wrote the book, The Iodine Crisis. And then, you have other doctors that feel differently. So, we have to agree to disagree. And I don't feel I know enough to feel I could take a stand on it. I'm in a state of flux.

Melanie Avalon: Reading his book, it's very convincing. And I do think there's probably a lot to maybe the difference between people who are eating a conventional diet, so they're getting iodized salt, compared to people who might not be having conventional salt, and so not having that source, I do wonder what role that plays. I do know iodine-- I know I've shared this on the show before I don't know if I've told you before. It's the only supplement that I experimented with that I had such obvious scary reaction that I was like, "I'm never taken this ever again." My eyes literally turned bloodshot red.

Cynthia Thurlow: Really?

Melanie Avalon: Yeah, that's kind of frightening [chuckles]. I remember I can't-- I can't even know if I can go to work. It was when I was still waiting tables. Yeah, so we will put links in the show notes. To the interviews we have had with all of these individuals.

One little announcement I do want to share with listeners, by the time this comes out, I feel bad because I think that this special will have already ended but the concept is still available, which is all the more reason you need to be on my email list for my AvalonX Supplements, which is avalonx.us/emaillist. And also, you can actually get text updates, and a 20% off one time code. I'm so excited, I set up text updates. If you text 'AvalonX' to 877-861-8318-- I'm just going to emphasize for clarity, Cynthia, have you ever set up a text service?

I have not. It's really funny because I say text 'AvalonX', all of the iterations I get of people texting that it's not AvalonX, people will text Avalons, or, give me the code or all these things. I'm like, "No, you have to text just the word AvalonX." So, it's a kind of like-- I don't know, it's just really funny to see all the messages. So, that's A-V-A-L-O-N-X to 877-861-8318. And if you are on that list, you would have known that we launched magnesium subscriptions. And we actually had a two-week window where you could get grandfathered in for life at a 25% discount, which is the largest discount we should technically probably ever do. And you get it for life as long as you stay on the subscription, which you can also pause. So, that's amazing, if you didn't snag the 25% you can still get a subscription now at 15%, so that's an option. Anything else from you, Cynthia?

Cynthia Thurlow: I am hopeful that we will finalize a package for the creatine so that I can get a date that this will be available. That is, I've got my fingers crossed.

Melanie Avalon: I'm very excited for you. Then someday, you'll have subscriptions on that as well, probably?

Cynthia Thurlow: Yes, you'll be able to tell me all about text options too.

Melanie Avalon: That's the thing I've learned, is be very clear in what people text to you.

Cynthia Thurlow: Keep it simple.

Melanie Avalon: It is simple, but people just extrapolate and text all the things and I'm like, "No, that is not what it says."

Cynthia Thurlow: It says not direct access to Melanie 24/7.

Melanie Avalon: Is not what it says.

Hi, friends. I'm about to tell you how you can get 15% off of my favorite bone broth, which is an incredible way to open your eating window. And all of the bones and this broth, Beauty & the Broth, are grass fed with no antibiotics or hormones and are traceable. Also, if you're suffering from mold or any autoimmune disease, bone broth is a basis of a lot of those protocols. But you want to make sure you are getting the best of the best. That's why I love Beauty & the Broth. Also, for all of you, vegetarians and vegans, stay tuned, because there's something for you too.

I've been talking about the incredible health effects of bone broth for years. Bone broth is so nourishing for our body. It's rich in collagen, which can really support your gut health, your skin, curb cravings, boost your energy and your immunity. But there are a lot of brands out there, a lot of them have ingredients that I don't like and making it yourself can also be very time consuming.

That's why I am thrilled about Beauty & the Broth. Beauty & the Broth was created by Melissa Bolona. She's an incredible actress and entrepreneur. I've had her on the Melanie Avalon Biohacking Podcast. I'll put a link to that in the show notes. But Melissa started Beauty & the Broth, after she realized the profound effect that bone broth was having on her own health, specifically gut issues, and its ability to give her radiant skin perfect for the camera. She founded Beauty & the Broth, which hit everything I could want in bone broth. It uses 100% whole organic ingredients. Yes, it is certified USDA organic. It is one of the only few bone broth companies in the entire US that has a USDA certification for organic bone broth. It has no artificial flavors, no preservatives, no phthalates, no sugar, and something that I love, no salt. Friends, even other bone broth that I really love always have salt added. This doesn't.

Her bone broths are made from grass-fed, ranch-raised beef and vegetarian-fed free-range chicken bones from certified humane USDA Organic Farms. And they are all traceable, meaning you can find exactly where these bones came from. And all certified organic vegetables are used in the broth as well. There's no antibiotics, no hormones, only the good stuff.

And here's the super cool thing about Beauty & the Broth. It can be a little bit of a hassle to transport bone broth. It's heavy, you have to keep it frozen. Guess what? Beauty & the Broth comes in shelf-stable packets with no preservatives that you keep at room temperature, and they are in concentrated form. That means that you add back water to reconstitute, and you can make it any strength that you like. They're single servings, so you can take them with you on the go, and even on the plane as yes, they are 3 ounces, and they're delicious. Oh, my goodness, friends, they will just make you light up. They're honestly, one of the most amazing things I've ever tasted. And for all of you vegans and vegetarians, Beauty & the Broth has a brand-new vegan broth concentrate. It is USDA organic and is a slow-simmer broth, which is reduced into a thick gelatinous gel. You mix it with hot water and turn it into a delicious sipping broth. It features organic mushrooms and chickpeas, ginger, seaweed, and pea protein. It is so delicious. So, definitely check that out. 

So, if you've been looking to finally jump on the bone broth train, do it now and do it with Beauty & the Broth. Melissa has an amazing offer just for our listeners. You can go to thebeautyandthebroth.com or melanieavalon.com/broth and use the coupon code, MELANIEAVALON, to get 15% off. That's thebeautyandthebroth.com with the coupon code, MELANIEAVALON, for 15% off. All of the listeners who have tried it, ever since I aired my episode with Melissa, have talked about how much they love it. It is so delicious, you guys will definitely love it. So, definitely check that out.

By the way, bone broth does break your fast. This is something that you want to have in your eating window. In fact, it's an amazing way to open your eating window, because when you're in that fasted state, when you take in bone broth as the first thing, all of those rich nutrients and collagen go straight to your gut, help heal your gut, help with leaky gut, help digestive issues. And again, you can go to thebeautyandthebroth.com and use the coupon code MELANIEAVALON for 15% off. I'll put all this information in the show notes. All right, now, back to the show.

Shall we jump into everything for today?

Cynthia Thurlow: Absolutely.

Melanie Avalon: To start things off, we have a question from Ashley and the subject is "Struggling with consistency." And Ashley says, "Hi, I have been a fan and I've listened to your podcast from the start, which means I started IF back in April of 2017. I wish I could say I have done IF every single day since then. But no, it has been the struggle bus for me to do it consistently." Typically, since 2017, I IF on average four to five days a week. Some weeks are better than others when I can complete six to seven days of IF, where other weeks are harder one to two days. My window varies from 16 hours to 24 hours. Really at this point, I have been in maintenance, at times losing and gaining 5 pounds.

Now that I'm approaching my third year of IF, I've hit a roadblock in the mornings. I find myself so hungry. I usually close my window at 7pm the night before having dinner with my husband is very important to me, which is why I don't want to break my fast in the morning. It seems lately, I can only make it to 12 hours before caving on eating something some days. What I'm getting at is, do you all have tips or advice for getting through these humps? Have you ever experienced it before? I'm disappointed in myself with the inconsistency I've done with fasting over the past couple of years, which I know leads to not getting the best results. I do love the health benefits of IF and never regret it when I do fast for at least 16. It's just some days I find myself starving, and then I cave. Any recommendations you have, I would appreciate so much. Thank you."

Cynthia Thurlow: Well, Ashley, I don't know how old you are. So, I'm going to just keep this a broad response. When a woman is telling me she really struggles to get to 12, 13,14 hours, I think you need to look at your macros. Are you getting enough protein? Are the meals that you're consuming in that feeding window, are they sufficient enough calorically to be able to fill your body? Where are you on your menstrual cycle? We know the follicular phase from the day you start bleeding up until before ovulation is a time that you can get away with longer fast. And then as you transition to the luteal phase, as you're getting closer to when you're going to get your menstrual cycle, I generally recommend women fast no more than 12 or 13 hours. So, I don't know if you're in a premenstrual situation and the end stage of luteal phase and that's why you're struggling. I would really dig into if you're feeling you're a little bit weight loss resistant, how's your sleep? How are you managing your stress? Are you getting enough macros in? Are you over exercising? So, there's a lot of variables that aren't entirely clear. And I just start to see a lot of women that get into these situations where they start to feel they're not seeing the results. So, they restrict more, they're just not feeling their bodies. And I get concerned that your body may in response to not feeling it's getting enough food and is really pushing the envelope. And if you're that hungry, I would definitely recommend breaking your fast, but also understanding that there are things you can do that could potentiate your fast, but I just feel I need more information to be more specific than I already have been. How about you, Melanie?

Melanie Avalon: Yeah, I thought that was great. I love how comprehensive that there are so many potential factors going on. I would just add to it that I think a lot of people, when they're having issues with and this is what you're talking about, but a lot people when they have issues with finding the fasting hours that work for them, they think the answer is in the fasting hours, like adjusting when they're fasting. But I personally find that looking at the food intake side of things can often be potentially just as helpful or more helpful than that. Especially when people send in questions, because we have a pattern of people who send in questions.

Some people, when they're discussing fasting and their issues, they also paint a very clear picture what they're eating. Some people don't mention it at all, it doesn't even come up in the question like this one. And I don't know this is the case but that says to me that it's possible that there's not as much of a focus on what you're eating as there could be that would possibly really, really help. So, making sure that you're getting adequate protein in your eating window, which we have a question about protein coming up. And for some people, it's looking at the macros that you're eating can actually be super helpful for satiety levels. So, some people do better with the lower carb approach, and that's what really helps them tap into fat burning and not be hungry. Some people do better with a higher carb approach, and actually, those carbs are what keeps them satiated. So, I would definitely look at what you're eating, there's a lot of potential to find something there, in addition to all of the other amazing things that Cynthia brought up.

Cynthia Thurlow: Now, it's such a good point, I think we have to look at things comprehensively. When a strategy is not working, it's okay to take a break from fasting. That's the other thing that I don't hear enough people talking about, that there are times and cycles in our lives when fasting really does well for us and times when it does not and it's okay to take a break. If you feel your body's really communicating that it's not working, there are definitely ways around that.

Melanie Avalon: Yes, exactly. Especially tying into-- I was just looking at the part where she's talking about how it's some weeks that are good, and some weeks that are harder. And I really, really wonder, you were talking about with the menstrual cycle, if it does align that way. I think oftentimes people, with the menstrual cycle, they don't make the connection that there's that connection going on there.

Cynthia Thurlow: Yep. Absolutely.

Melanie Avalon: All righty. Shall we go into our next question?

Cynthia Thurlow: Absolutely, this question is from Monica. And the subject is "Third time's a charm." "I've listened to your whole podcast. I love all the information. It has seriously been so helpful in my fasting journey. Fasting has helped me overcome so much. Major hormone imbalances and an obsession over food that is totally mellowed out with the control I feel with fasting. It's wonderful and truly life changing. My question is something I never really thought could be an issue. But I found an article that said otherwise. Can a diet focused primarily around protein contribute to insulin resistance? I follow Dr. Ted Naiman who is a huge fan of protein over pretty much all else. But if you're constantly getting the spike in insulin from protein, could not have the same effect on our tolerance of insulin as sugar does. For example, a diet of low carb high protein low to moderate fat. I'd love to hear your thoughts and research. Love you guys. Seriously keep it up."

Melanie Avalon: Okay, Monica, thank you so much for your question. Really, I got so excited about researching this question, and I did a lot of research. So, I'm so excited to talk about this. So, yes, protein does release insulin. The difference between how it releases insulin compared to carbohydrates, for example, it varies. I was looking at a lot of different literature and there are charts on different foods and insulin release. And some charts will say, for example, that beef releases more insulin than carbs. But then, something else I was looking at was saying that protein requires about half of the insulin of carbs. So, it seems to be all over the place. But the point is, they both do release insulin in substantial amounts compared to fat, which is very, very minimal.

The difference with protein is it also releases a hormone called glucagon. And you can think of glucagon as the counter-regulatory hormones to insulin. So, insulin reduces blood sugar, puts sugar into storage. Glucagon actually spurs the liver to release glucose into the bloodstream. Let's say you're just eating protein, and you are nondiabetic, and you are good with your insulin regulation in general, in theory, you would eat some protein. And because you're not eating carbs with it, this is my example, the insulin would lower your blood sugar, actually, and then glucagon would actually encourage your liver to release glucose. And then, you just have a straight-line response, and you wouldn't really have those dips and swings.

All of that said, there can be some issues, potentially with, one, the fact that protein does release insulin. So, if we are eating a lot of protein constantly, we could be getting-- it could potentially encourage insulin resistance from all that insulin release, especially in the context of if you're eating a mixed diet, and you're also getting insulin released from carbs and things like that. And then, releasing the glucagon can actually also potentially be a problem, because now not only are we releasing insulin to store carbs that we might be eating with a meal, but we're also potentially releasing glucose from the liver, which might create a longer-term blood sugar insulin issue.

On top of that, the constant release of-- protein stimulates something called mTOR, which actually, it's a growth signal in the body. And there are studies on mTOR and insulin sensitivity, and too much stimulation of mTOR constantly, might also encourage insulin resistance. And then on top of that, there's a lot of studies on BCAAs. So, those are branched chain amino acids. They are some of the potential amino acids that we can get from protein. And studies are pretty consistent that high levels of those in the blood tend to correlate to insulin resistance. But the problem is, we don't know if it's chicken or egg. We don't know if high BCAAs in the blood cause insulin resistance. Or if when you are insulin resistant, your body is unable to properly get those BCAAs out of the blood. And the studies are very conflicting and inconclusive on the BCAAs.

I found a very amazing study that literally looks at this question that Monica had. It's from July 2014 and it's called, "High dietary protein intake, reducing or eliciting insulin resistance?" And it looked at all the studies to date. So again, it's a little bit older of a study, 2014. But it was looking at the studies to date that all looked at high protein intakes in different situations, and how did it affect insulin resistance and glucose control in the subjects. And I actually, because there's a lot-- It's a very long article. I actually went through and counted, because they didn't really give a graph. I just went through and counted what they actually found. I'm going to tell you because I find it very telling.

In studies of healthy people who are not obese, who are not losing weight, so this is a short-term, energy-balanced high protein diet. Basically, just going on a high protein diet for the short term, not calorie restricted, not losing weight. Three other studies found that when they compare that to a normal diet, there was no effect on insulin resistance, so we didn't see a negative effect there. And then, one study found a benefit, so that's favorable. The second category was people who are overweight also doing the same thing. Short term, they're eating a high protein diet, but they are not losing weight. One of the studies found that when they made the protein high diet with whey protein that there was a benefit. And when I say benefit, I'm talking about on insulin resistance. One study found that there was no change, so there wasn't any difference. One study found when they use casein and whey that there was no change. Another study was six weeks, it was high protein, and the protein was from legumes and whey, and they found that it actually-- the high protein decreased insulin sensitivity, but then it actually normalized the longer the people were on it. Another study in diabetics with that setup found that the high protein improved insulin sensitivity. The conclusion was that it's inconclusive.

Then, they looked at people who are on short-term diets where they were calorie restricted and high protein, and losing weight. And in those, well, they started off by saying that most weight loss diets leading to weight loss increase insulin resistance. So, if you're on a high protein diet and you lose weight, you're probably going to see a benefit in insulin sensitivity. But it's hard to know if it's from the protein or if it's from the weight loss. They found that two studies compared high protein diets to other calorie-restricted diets for weight loss and the high protein diets had more of a benefit. One study found, comparing it to a control, so not to a calorie-restricted diet, it found a benefit. One study found that the high protein diet did not have as beneficial of an effect on Homa IR, which is a good marker of insulin sensitivity, but it did have a better effect on beta cell function and the pancreas. So, that's a little bit confusing. And then, two studies found that it was the same benefit. And then, one study found that it was looking at high protein versus high carb in a calorie-restricted situation, and the high carb was superior.

Last category, I'm almost done. And then, the section looking at long-term intake of high protein diets, one study looked at six months of people who are healthy on high protein diets. And they found that those on the higher protein diets had higher insulin resistance and more glucose issues. A collection of observational studies on diabetes found that high protein diets led to more issues. But then The Nurses' Health Study looked at low carb high protein diets and they did not find those issues. And then they actually did find that long-term intake of high protein from vegetable protein actually benefited insulin resistance. And then, there was another meta-analysis that they referenced. And that looked at 15 randomized control trials of more than 12 months on the long-term effects of diets high in protein. And it showed neither a positive nor a negative effect on glycemic control compared to diet low in protein in both healthy and insulin-resistant subjects.

Okay, sorry that that was so much information. But basically, there's been a lot of studies looking at this issue. Like I just went through all of those, the effects seem to be pretty mixed. It's interesting, because the study I was referencing, they concluded that high-protein diets and insulin action are not univocal, which means unambiguous. So basically, it is ambiguous. And that insulin sensitivity seems to have a beneficial effect in high-protein diets when people are overweight or insulin resistant, and they are losing weight. In the short term, having a high protein diet doesn't seem to really affect insulin action. But in the long term, there might be a-- or they say it seems to be deleterious when the intake is prolonged. And that this goes along with seeing high plasma BCAA levels in the blood, like I was talking about. Their ultimate conclusion is that in the long term, increased insulin secretion and consequent hyperinsulinemia might lead to reduced hepatic insulin sensitivity. Increased hepatic glucose output results in a decrease glucose control, although a direct effect in insulin action and insulin sensitive tissues can also have a role.

My thoughts stepping away from all of this is that yes, if you are doing high protein-- well, especially if you're doing high protein in the context of energy-toxic diet, a diet with too much energy in the long term, I think definitely can encourage an issue, contribute to an issue. If you're eating protein constantly 24/7, it could have those issues with mTOR. It could have basically all of these issues. In the context of weight loss, I don't think most people would need to worry about this at all. In maintenance as well. I'm not sure but I do feel for people who are doing intermittent fasting, we're getting that period during the fast of low insulin. We're getting that period of low mTOR. I think it's crucial that we get adequate if not high protein when we do eat. So basically, I really think that the issue here is energy toxicity, not protein completely. That was a really long answer. Cynthia, do you have thoughts?

Cynthia Thurlow: No, I am in awe of the research that you did. My clinical context, just thinking thoughtfully about this question is, I'm 100% in agreement that the energy toxicity, meaning you're eating too much food, is really the issue. Now, when we look at the bulk of the population, we know 92-93% is metabolically inflexible and unhealthy, it is likely not too much protein, that's the issue. It's the overall there's just too much caloric or the macros are imbalanced. It's overwhelming the body's storage sites. And it is less about protein, and more about all of the other factors. Most people, perhaps not our listeners, but most individuals here in the United States are drinking caloric beverages all day long. They're eating anywhere from 6 to 10 times a day. And when you're really looking at the degree of meal frequency, the average American is doing-- average westernized person combined with those beverages, I think that is a greater issue. And for them, if they suddenly go high protein, and they still have all these other behaviors that I've identified, then that can become a larger issue.

And it's interesting, Ted Naiman, I've interviewed and I'm very aligned with him on many, many things. And he has this amazing book that is only an electronic book, which means I don't own it, because I like having physical books for most of my things that I want to reference. But he posts a lot of fantastic content on Twitter and YouTube. And it's a great resource. And he talks about how a certain amount of protein and fats will shut that satiety, you'll hit those satiety hormones that you just physically can't consume more food. And I think that's an important distinction along with everything else that you said. But I'm so grateful you did all that amazing research. I'm just going to speak to it as a clinician, and I think it has everything to do with an overconsumption of calories, in general, that is creating this toxicity and this degree of lack of metabolic flexibility and insulin resistance.

Melanie Avalon: Yeah, what you just said is basically exactly how I feel. And I think the nuance as well is that, so say we are in energy toxicity situation on a low protein diet, the energy toxicity is primarily coming from carbs and fat. Just stepping aside, in general, energy toxicity is, I think, the issue. If you have low protein, the factor that you don't have going on in that situation, is that you're not getting that glucagon stimulation, that would be prompting the liver to be constantly also releasing glucose from the liver, which would be further exacerbating issues as well as the potential buildup of those amino acids in the bloodstream. Compared to when you do have the protein, you've got that secondary issue going on.

And I did want to throw in, because I left out one other thing because that was 2014. There was actually a 2020 meta-analysis, and it looked at 12 articles with 13 studies including patients with diabetes, and they actually concluded that a high protein diet does not significantly improve glycemic control and blood pressure. They didn't say that it hurt it, they just said it doesn't improve it. But it can lower LDL, TC, TG and Homa IR levels in patients with type 2 diabetes. Further studies are needed to clarify the effects of high protein diet and glycemic control, insulin resistance and blood pressure control and type 2 diabetes. I just want to throw that one in there because I left it out.

But I'm glad you brought up Ted Naiman, I love him, we can put links to the episodes that we've had with him. I also really love Marty Kendall. He had a really good article on the glucagon aspect of this that I was reading, and he actually referenced Ted Naiman in that study as well. All that to say I agree with-- what you just said is what I agree with that. I think the issue is the energy toxicity.

Cynthia Thurlow: No, it definitely makes sense.

Melanie Avalon: Okay, I don't know if Monica expected that long of an answer. [Cynthia laughs] All right, we have a question from Jessica, and the subject is "Menopause, HRT, etc." Jessica says, "Hi, I love this podcast and I learned so much about IF. My doctor advised me to start IF a month ago when she put me on HRT. I'm 37 and still breastfeeding my daughter aged one, but I'm also postmenopausal as my ovaries were removed in December. My doctor advised HRT because my estrogen was unsurprisingly very low, and my DHEA and testosterone were very high. I've been doing IF starting at 16:8 a month ago, and now usually doing 18:6 and sometimes 20:4. I have not lost a single pound. My clothes do not fit differently. I am at my highest weight ever and getting so discouraged every time I step on the scale.

I have now been on low doses of bioidentical estrogen and progesterone for a month while doing IF. And although I feel some benefits, it's helped some digestive issues. I need the scale to move in order to feel my health is improving. Losing even a few pounds would give me hope, but it is just not happening. How long do I stick with this before it's time to admit it is not working for me? I'm also a vegetarian, but I sometimes eat the occasional fish. I'm reading that the research on IF for women is mixed, and it may have negative consequences for postmenopausal women. Is it possible this just isn’t for me? I hope that's not the case. Because this is the only diet, I've ever tried that I felt was sustainable. Thanks in advance, keep up the good work."

Cynthia Thurlow: Ah, Jessica, you have a lot going on. Oh, my goodness. You're still a very young woman, and we know women that have their ovaries removed before the age of 42 are at greater risk for developing cognitive issues. So, I'm grateful that your doctor is being very proactive and considering hormone replacement therapy. My concern is, and I'm just going to start from the top, I'm not in agreement with women breastfeeding or being pregnant and fasting. You're wanting to lose fat, but your body is still feeding a baby. And I'm sure if she's one, she's probably eating a lot of solids. And so, her breastfeeding might be brief and just a few times a day. But just something to think about in the position that you're in, you're giving your body mixed signals. You want it to lose fat, but you still want to be able to sustain being able to breastfeed, and I find for most women while they're breastfeeding, it's harder for them to lose body fat. So, that's number one. Since you're so young, I'm curious to know why your ovaries were removed at such a young age because that's very significant.

You're mentioning that your testosterone was high. The question is why. Did you have polycystic ovarian syndrome? When I start thinking about the reasons why women can have high testosterone, that's almost always the first thing I think about. Does your husband take supplemental testosterone? Probably not, because you're both very young, but you can sometimes get exogenous exposure that way. Just in thinking about the bioidentical hormones, it could be a combination of too much stress on the body, breastfeeding, fasting. Going into menopause is a big adjustment, and you have surgical menopause, meaning the average age of a woman in the United States to go through menopause is 51. You're 37. So, you're very, very young. And so, from my perspective, it's trying to get a sense from what you've shared as to what could be going on.

The other thing that I get concerned about is most vegetarians in my clinical experience consume too many carbohydrates, not enough protein. And you really have to work at that very diligently. If you're eating very limited, animal-based protein, hopefully, you're eating some eggs, which will make that easier. But the challenge is, if you're trying to fuel weight loss and you are vegetarian, you're very likely overconsuming carbohydrates. And then, you're also breastfeeding, and your body needs a little bit of extra fuel to be able to make that happen. I wrote a whole book about women and fasting.

And I generally will suggest the women check that out. There is research on postmenopausal women. And I find the women that generally do the best are the women who have stable hormones, meaning, when you're no longer menstruating, your hormone levels are stable, much more stable day to day, week to week than a woman who's still in peak fertile years, or even a perimenopausal woman-- there's a lot of good research that women can do very well in menopause, with intermittent fasting, provided that they're sleeping high quality sleep, they're managing their stress. And as a new mom, it's not unstressful to have a little baby at home and then stressing about trying to lose weight. I mean, those are two big things, eating anti-inflammatory nutrition, and really thinking about, things that fuel insulin sensitivity. And I think about walking after a meal, and lifting weights and things like that.

So, there's a lot to unpack here, I would give it more time. If you're breastfeeding, you need to give yourself some time. I used to always say six months was always that time period that I felt most of my patients got to a point where they were starting to see some weight loss, 12 to 18 months. And if you're still breastfeeding, it's going to make it a whole lot harder to lose weight. So, please give yourself some grace. Make sure you're getting your hormones tested, make sure you've got a DUTCH as well as serum blood labs. I think that would be very helpful. And the other question that dovetails into that is why is your testosterone so high? Did you have PCOS? What was the precipitant for removing your ovaries? That's a pretty drastic surgery for such a young woman. I would imagine there's a good reason, but just not a reason that's entirely clear to me right now. What do you think, Melanie?

Melanie Avalon: Well, I thought that was absolutely amazing and comprehensive. That was one of the takeaways I really took away from reading your book, Intermittent Fasting Transformation, was the difference with fasting in pre-menopausal and postmenopausal women and where do you think this idea-- because people ask this a lot or say this, that there are negative consequences for postmenopausal. But have you seen that? I mean, would the concern be I guess sarcopenia, not getting enough protein? I'm just wondering where this idea is coming from.

Cynthia Thurlow: I think there's a degree of fear mongering This is why I'm not a fan of OMAD. And that may upset people but I'm going to just say it, you just can't get your macros in. And once you're going through perimenopause, and menopause, physiologically, we are just much more at risk for muscle loss and the way that you need to think about how important and-- Gabrielle Lyon has been on your podcast, she has been on my podcast, she's a really close friend. I tell her all the time that her work completely changed everything that I talked about. But you want to think about muscles as a glucose reservoir. They're critically important for being metabolically healthy. And as you are losing muscle, and that's being replaced by fat--

I always talk about the filet, which is young muscle. Melanie has young muscle Melanie, so Melanie is a big fillet. And I'm 51, so my muscles, if I don't work really hard, are going to look like a ribeye and a ribeye is delicious. But we want to be a filet for as long as we can be. And I'm not talking about aesthetics. I'm talking about musculature, it's so important. And the concern I get is when postmenopausal women, perimenopausal women are just bucking this trend of, "I'm only hungry for one meal a day and that's all I eat," I just have to remind them, one of the reasons why you're not more-hungry, is you're starting to lose lean muscle mass. And as Gabrielle says, "You are not overfed, you're undermuscled." So, it's really important to understand that I think a lot of the concerns and fear about menopausal women is largely a byproduct of this concern that they are going to lose muscle mass if they're not eating at least two meals a day, we're not talking about 6 meals a day, or 10 meals a day, which I eat two meals a day so that you can get enough protein in your diet.

The other thing that I think is important note is that we're de facto less tolerant of stress as we head into perimenopause and menopause. It's a byproduct of the loss of progesterone from our ovaries, as our adrenals are stepping in to help support our body, we are just not as stress resilient. That doesn't mean we can't manage stress, we don't manage it as well. And so, I think on a lot of levels, there's this concern that if women head into their 40s, and 50s and beyond, and they're overfasting, overrestricting, not exercising or doing the wrong types of exercise, that they can put themselves at risk for a lot of inflammation, a lot of bodily stress. But I sometimes feel menopausal women have an easier time because they don't have to deal with the factors of a menstrual cycle and follicular phase and luteal phase. I would say men and menopausal women can sometimes have the easiest time fasting of all because they don't have to worry about this biology of procreation and conception and fertility and infertility that younger women have to worry about. But I do think it's a huge problem.

In fact, I'm not going to say this person's name, but there's a person who just had a book come out and they love to fearmonger about women and fasting. And I've had to have this discussion quite a bit. And I don't want anyone to perceive that. If you're sleeping well and you're dialing in on your nutrition and you're managing your stress and you're fasting for your cycle and you're not overexercising, that fasting can't be a part of or eating less often, can't be part of your strategies that you use to feel good about navigating whatever stage of life you're in. I think a lot of that comes from well-meaning people who don't really know what's going on. That's my feeling.

Melanie Avalon: I cannot agree more. It's actually similar or relates to the findings speaking of what you're talking about earlier with protein, on protein and longevity. There are so many people, researchers and such like Dr. Valter Longo, who I've had on the show-- he's actually been on this show, and he's been on the biohacking podcast, but he and people in his sphere are very much pro low protein for longevity up until, I think, age 60. And then, you need higher protein. So, I think that does relate to everything Cynthia was talking about, about when you are at that older age and the more difficulty it is to create and maintain muscle, women in particular really need the higher protein when they're older. I don't think that should be lumped in with the fasting, which I think can happen. It just might be like Cynthia was saying that you need a longer window to get in that adequate protein intake if you're not like me where I eat all the protein.

Cynthia Thurlow: The unicorn, but I think that's one of the reasons why I love podcasting with you as we really speak to such a wide age range of women. And I think that's really important because if we were both 50 somethings or if we're both 30 somethings, we would not necessarily totally represent our demographic, right?

Melanie Avalon: Yeah, exactly. It's funny before I even started the show, way back, I remember brainstorming about what did I want the show to look like. And at first, I was like "Oh, I want to cohost with somebody like my age. And it'll be two girls having wine night, two young people." But when I met Jen, I was "Oh, this is actually much more appropriate," because it's just so much helpful to give the broad perspective, and then it's even better when we're friends as well. It's all the good things.

Cynthia Thurlow: Exactly. And I think it's important for people to understand that there's a genuine camaraderie here. So, we can both benefit from our own experiences. My kids know who Melanie is. When we talk about Melanie's eating window, and her sleeping habits and how different we both are, and that's the beauty of it is that there's listeners who very likely-- there might be someone who has a long, evening eating window and stays up really late-- And I think, it's only when I was traveling in Europe that we overlapped at the same time, like we were awake for the longest stretch of time at the same time. I was like, "This is cool."

Melanie Avalon: Yeah. It's funny, I get DMs from people because I do think my approach is very rare. But there are? I know you guys are out there who actually do it very similar to me, and quite a few people DM me, and they're just like, "Thank you for letting me know I'm not alone in my crazy late night, feast every night." So, we are out there, but it definitely doesn't work for everybody, that is for sure.

Friends, I'm about to tell you how you can get 50% off a product that has truly changed my life. Do you experience stress, or anxiety, or chronic pain? Do you have trouble sleeping at least once a week? If you do, trust me, you are not alone. I personally have explored so many avenues for how to have a healthy relationship with stress and finding the world of CBD oil has been absolutely incredible for that. After doing more and more research, I've realized just how incredible the health benefits of CBD are. CBD regulates your cannabinoid system, kind of like an adaptogen, making you feel better naturally. It's not addictive, it's not a crutch. Basically, it's just helping your body function better when it comes to stress, anxiety, pain, and sleeplessness. I take it daily for my mood and the effects are profound. In fact, I even got robbed last year and I went from crying with stress and anxiety to taking some Feals and laughing. I said to my mom, "Mom, see how effective this is?"

Due to all of its health benefits, we knew we wanted to partner with a CBD company for the podcast. But I have very stringent criteria. You guys know this. So many brands approached us, and I kept just saying no because nothing fit all of my criteria. I wanted a CBD oil that was full spectrum, tested for purity, organic, made with MCT oil as the carrier, and that I actually experienced benefits from. That's a pretty tall order to fill. We said no to a lot of brands, and then Feals came along, and it was meant to be. I personally tried it out and started seeing massive effects on my sleep and stress. Feals is so easy to take. You can just put a few drops under your tongue, and you'll feel the difference within minutes. I truly do feel it within minutes. Of course, it is important to remember that CBD works differently for everybody based on your own unique cannabinoid system, so you might need to work to find your perfect dose. Experiment over the course of a week or so, and you may find that you need more or less depending on the effects that you're looking for. 

I'm also super grateful because they have an incredible offer for our audience. You can start feeling better with Feals. Become a member today by going to feals.com/ifpodcast and you'll get 50% off your first order with free shipping. That's feals.com/ifpodcast to become a member and get 50% automatically taken off your first order with free shipping. feals.com/ifpodcast. When you get that offer, you'll be joining the Feals community and you'll get Feals delivered directly to your doorstep every month. You'll save money on every order and of course, you can pause or cancel anytime. So, definitely try it out for the first month with our code for 50% off and see how it works for you. We'll put all this information in the show notes. All right, now, back to the show.

All right. Shall we answer one more question?

Cynthia Thurlow: Absolutely. This is Mary, "Prescription meds breaking fast." "Hello, I've just begun IF." So, her eating is either 19:5 for two days or 20:4. "I've long abstained from between meal eating, so this was a fairly easy transition for me. I am determined to have clean fast. However, I saw a comment today on Facebook regarding melatonin, and the word was that it does contain sugar, so realistically breaks the fast. I have a long list of prescription meds. So far, I've looked at four that are must-haves, and they all have that same ingredient. My feeding window is 12:30 to 4:30. I can take my evening pills right at 4:30 and some of my AM pills right at 12:30. But some must be taken 12 hours apart. My question is, if I take the must-haves when I wake up, does that wreck my clean fast? Eager to hear. I want to do this right. Thank you for your time, Mary."

Melanie Avalon: All right, Mary, thank you so much for your question. So, something to clarify, because I can see how this can happen. You talked about how you heard melatonin, and it contains sugar, and so, it breaks the fast. And maybe this goes without saying but with something like melatonin, which is not a prescription, there are many brands of melatonin, and they do not all contain sugar. So, melatonin does not equal sugar, does not require sugar to be taken. For melatonin, for example, you can find a melatonin that is fast friendly. We love melatonin from MD Logic for example. So definitely check them out. You can use the codes, MELANIEAVALON or CYNTHIA, to get a discount on that I know Cynthia in particular has really benefited from that melatonin. So that's supplements like non-prescriptive supplements, you can usually find a version that is clean, fast friendly, especially when it's not a prescription because there's normally lots of versions of it.

When it comes to prescription medications, if you have to be taking your prescription medications, you have to be taking your prescription medications. Some of them might contain ingredients that break the fast like she has found out. I'd be curious what she found in it that was-- I'm wondering what the sugar ingredient that she's thinking. I'm wondering if it's something-- I'm just wondering what it is exactly. There are a few things. One, I think a lot of people don't realize this, but this is actually an option. You can actually get a lot of prescription medications compounded, I actually do. If you have a compounding pharmacy that you like and can work with, they can often make compounded versions of your medication with the exact fillers that you want, or even no fillers. It's not always a possibility. And sometimes if it's a possibility, it's extremely expensive, so then it's not really a possibility. But for some of the medications, it is a possibility. I've done that in the past for things.

If that's not the case and you need to go with the traditional prescription form, there are a lot of generic versions of a lot of prescription medications. You can look up the prescription and you can try to find the one that is the most "fast friendly." It does take a little bit of detective work, I'm thinking of little detective emoji in my head. But that is an option. And you can talk with your doctor if you want a specific generic version prescribed. All of that said, if you need to take the prescription medication and you cannot find a clean, fast friendly and you cannot get it compounded. It's okay, [chuckles] you have to take your medications when you have to take them. It's not like this is actual food. I'm not giving a greenlight to taking in minute amounts of sugar or anything that in general. But when it comes to medication, you have to take your medication. Don't stress about it. It will be very minimal, if anything. Those are my thoughts on medication. Cynthia?

Cynthia Thurlow: The irony is I have 45 cohort going right now, and we had our first group call. And that was the first question that I was asked today. And here's the thing, if you have to take a medication, you have to take a medication, period. There should be no stress about, does it break your fast, does it not breaks your fast? I'm always very transparent talk about the fact I take now compounded thyroid medicine, and I take that during my fasting window and that does not break my fast. Now, the issue with generics, and people may not know this, but you can get these tremendous variances. There are generics you can get sometimes like 20% variants. As an example, before I was taking compounded progesterone, I would sometimes wonder why some nights I'd sleep really well and some nights I wouldn't. My functional med doc actually pointed out, "Well, you realize, you probably remember this but for generic medications, even though it's a bioidentical, you still have this variance." And so, I would just state that-- sometimes the trade medications that you pay a little more for-- and by no means am I telling people to break their budget to do this, but if you feel you don't do as well on a generic, just understand it can be 20% different than the trade product. I had a lot of women, especially my thyroid patients, that would tell me they would not take generic Synthroid. They only took regular Synthroid because they had intolerances. I had patients on antihypertensive, so medications for their blood pressure, same thing. We're all individuals but please do not let the concern about breaking a clean fast be the reason why you perceive that you have to do all these different things to me make this work.

Now, there should be no sugar in melatonin. And if there is, then I would definitely look for another option. I speak very openly that the two options I use are Sandman, that's a whole other special conversation about that supplement. But the MD Logic melatonin is more efficacious, meaning it's stronger than the Designs for Health product I'd been using for several years, and I even used on myself as well as my patients. One capsule of MD logic was equivalent to three of the Designs for Health sustained release. To give you an idea, it's very cost effective, and I'm not sharing that to sell everyone on that brand, but just to share that's what works for me. Sandman is a per rectal melatonin, but it's also largely cost prohibitive for the average person, I probably use it twice a month. But with that being said, please don't let that be a concern. Now, if your supplement has sugar in it-- there was a woman in my other group who had a product that had 40 grams of sugar and 30 grams of carbs. And I was like, "First of all, you need to throw that in the garbage."

Melanie Avalon: In what? Supplement?

Cynthia Thurlow: Yeah, there were gummies. And I said, "Okay, well, a gummy is going to be full of sugar, because it's going to be soft and--" Anyway, a whole separate conversation. But the point of what I'm sharing is, we want to try to find the cleanest options that are out there. Things without gluten and dairy and grains and soy, just be diligent when you're selecting supplements to try to find really high-quality products. Yeah, that's my ramp. But please don't let concerns about your medication breaking your fast keep you from taking medications that you are prescribed and that you need.

Melanie Avalon: That's so fascinating. I know you said you've seen it in hypertensive medications as well. Do you find it is more the hormonal supplements where that's an issue or is it just across the board?

Cynthia Thurlow: Well, it's interesting, because many years ago, when I was taking oral contraceptives, I remember when I was a student at Hopkins, I had this one brand of oral contraceptives. And I also had mild phenotype PCOS, I had no idea why I had these crazy wild periods. Well, it's because I had PCOS and that's why I initially went on the pill. And the student health center was "Oh, we've got the generic version of what you're taking." I went on the generic and gained 10 pounds. And I remember them saying, "Oh, there's nothing different in this." And then, I remember talking to my faculty, and they were like generic is exactly that. They only have to have 80% of the formulation the same.

Melanie Avalon: Legally?

Cynthia Thurlow: Yeah, and you can have different fillers. There's lots of things that happen with these medications that I used to say-- Some people do fine with the generics, let me be clear, there's nothing wrong with generics. But I think there are definitely people who are much more sensitive to additional fillers and different formulations of medications. And so, that's where I think it's important to just have the conversation. If you're doing fine on what you're taking, great. If you're not, investigate what other options are available.

Melanie Avalon: Wow. It's interesting, because I had sort of vaguely wondered that in general about the generics, but I hadn't really looked into it.

Cynthia Thurlow: Yeah, up to 20%.

Melanie Avalon: Um, it's concerning.

Cynthia Thurlow: Yeah.

Melanie Avalon: Well, thank you. That's very valuable information. Thank you for sharing.

Cynthia Thurlow: You're welcome. It'd be a little depressing for everyone to hear. But the irony is one of my pharmacist friends and one of my doctor friends just happened to say that to me the other day, and I was like "Oh, my gosh, I forgot that. It's so true. It makes complete sense."

Melanie Avalon: Wow, wow, wow. Well, thank you.

Cynthia Thurlow: You're welcome.

Melanie Avalon: For listeners, if you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. The show notes for today's episode, which are going to have a lot of links, as well as a full transcript, will be @ifpodcast.com/episode286. And then, you can get all the stuff that we like at ifpodcast.com/stuffwelike. And you can follow us on Instagram. We are @ifpodcast. I am @melanieavalon, and Cynthia is @cynthia_thurlow_. All right. Well, this has been absolutely wonderful. And I will talk to you next week.

Cynthia Thurlow: It sounds good.

Melanie Avalon: Bye.

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman. Editing by Podcast Doctors. Show notes and artwork by Brianna Joyner. Transcripts by SpeechDocs. And original theme composed by Leland Cox and recomposed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Jul 03

Episode 272: Allergies, Cancer Cells, Hypothyroidism, Menopause, PCOS, High Carb Low Fat, Snacking, Low Iron, And More!

Intermittent Fasting

Welcome to Episode 272 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

FEALS: Feals makes CBD oil which satisfies ALL of Melanie's stringent criteria: it's premium, full spectrum, organic, tested, pure CBD in MCT oil! It's delivered directly to your doorstep. CBD supports the body's natural cannabinoid system, and can address an array of issues, from sleep to stress to chronic pain, and more! Go To feals.com/ifpodcast To Become A Member And Get 50% Off Your First Order, With Free Shipping!

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To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

FEALS: Go To feals.com/ifpodcast To Become A Member And Get 50% Off Your First Order, With Free Shipping!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

Ravenous: Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection (sam Apple)

The Cancer Code: A Revolutionary New Understanding of a Medical Mystery (Dr. Jason Fung)

GREENCHEF: Go To greenchef.com/ifpodcast135 And Use Code Ifpodcast135 To Get $135 Off Across Five
Boxes, Plus Free Shipping On Your First Box!

Listener Feedback: Sarah - CGM

The Melanie Avalon Biohacking Podcast Episode #146 - Dr. Rick Johnson

Ep. 205 – Fructose – The Driver Behind Metabolic Disease with Dr. Rick Johnson

Listener Q&A: Cia - Help me please!

The Paleo Thyroid Solution: Stop Feeling Fat, Foggy, And Fatigued At The Hands Of Uninformed Doctors - Reclaim Your Health! (Elle Russ)

Cynthia's favorite Thyroid resources

The Institute For Functional Medicine

Listener Q&A: Gab - Podcast question

Ep. 211 – Addressing the Root Cause of Hormonal Imbalances with Dr. Sara Gottfried

Eat For Energy: How To Beat Fatigue, Supercharge Your Mitochondria, And Unlock All-Day Energy (Alex Leaf M.S. and Ari Whitten)

Natural Force Organic Pure C8 MCT Oil – Liquid MCT Oil in Glass Bottle

LMNT: For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase! Learn All About Electrolytes In Episode 237 - Our Interview With Robb Wolf!

Listener Q&A: Christina - Confused on eating in window

Listener Q&A: Michelle - Blood Work

Cu-RE Your Fatigue: The Root Cause and How To Fix It On Your Own (Morley M. Robbins)

Ep. 213 All About Electrolytes: Symptoms, Causes, and Solutions for Electrolyte Imbalance with Robb Wolf

Simply Hydration: Magnesium-Charged Electrolyte Concentrate for Rapid Hydration

Use the link melanieavalon.com/ancestral with the code Avalon10 to get 10% off ancestral supplements!

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 272 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time, and get ready for The Intermittent Fasting Podcast.

Friends, I'm about to tell you how you can get 50% off a product that has truly changed my life. Do you experience stress, or anxiety, or chronic pain? Do you have trouble sleeping at least once a week? If you do, trust me, you are not alone. I personally have explored so many avenues for how to have a healthy relationship with stress and finding the world of CBD oil has been absolutely incredible for that. After doing more and more research, I realized just how incredible the health benefits of CBD are. CBD regulates your cannabinoid system like an adaptogen making you feel better naturally. It's not addictive, it's not a crutch, basically it's just helping your body function better when it comes to stress, anxiety, pain, and sleeplessness. I take it daily for my mood and the effects are profound. In fact, I even got robbed last year and I went from crying with stress and anxiety to taking some Feals and laughing. I said to my mom, "Mom, see how effective this is?" Due to all of its health benefits, we knew we wanted to partner with a CBD company for the podcast. But I have very stringent criteria. You guys know this. So many brands approached us and I kept just saying, “No, because nothing fit all of my criteria.” I wanted CBD oil that was full spectrum, tested for purity, organic, made with MCT oil as the carrier, and that I actually experience benefits from. That's a pretty tall order to fill. We said no to a lot of brands, and then Feals came along, and it was meant to be. I personally tried it out and started seeing massive effects on my sleep and stress. Feals is so easy to take. You can just put a few drops under your tongue and you'll feel the difference within minutes. I truly do feel it within minutes. 

Of course, it is important to remember that CBD works differently for everybody based on your own unique cannabinoid system, so, you might need to work to find your perfect dose. Experiment over the course of a week or so, and you may find that you need more or less depending on the effects that you're looking for. I'm also super grateful because they have an incredible offer for our audience. You can start feeling better with Feals. Become a member today by going to feals.com/ifpodcast and you'll get 50% off your first order with free shipping. That's FEALS dotcom slash IFPODCAST to become a member and get 50% automatically taken off your first order with free shipping. feals.com/ifpodcast. When you get that offer, you'll be joining the Feals community and you'll get Feals delivered directly to your doorstep every month. You'll save money on every order and of course, you can pause or cancel anytime. So, definitely try it out for the first month with our code for 50% off and see how it works for you. We'll put all this information in the show notes.

And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting, it's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup maybe playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That's because ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years. 

Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so, you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life and their makeup is amazing. Check on my Instagram to see what it looks like. Tina Fey, even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my clean beauty email list, that's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well. 

And lastly, if you're thinking of making Clean Beauty and Safe Skincare, a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show.

Melanie Avalon: Hi, everybody and welcome. This is Episode number 272 of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with, Cynthia Thurlow.

Cynthia Thurlow: Hey, Melanie. How are you today?

Melanie Avalon: I'm good. How about you?

Cynthia Thurlow: I'm great. In three days, I will be on vacation with my family. 

Melanie Avalon: This is very exciting. 

Cynthia Thurlow: It is really exciting. The most exciting part that I've realized is that now, my children are old enough that they have to get all their clothing and all of their things together without my help. 

Melanie Avalon: Oh, that's nice.

Cynthia Thurlow: It’s a huge milestone. For 17 years, I've been packing four people for trips and now, technically, I'm guiding two, and I'm only packing one, and that's very exciting.

Melanie Avalon: I should after this call my mother and thank her for all the time she did that. [chuckles] I think my favorite part of traveling when we were little was everything, she would pack us for the plane ride.

Cynthia Thurlow: I used to do all that. Now, I've got two surly, yet wonderful teenage boys. Other than making sure, I've got one EpiPen packed and a couple sundry things. They're very fairly independent. Let me make-- I provide that qualifier. But I'm Marvel now when we get on planes that I don't have to-- Let me just backtrack. When you have younger children, it's like, “I don't want them to have a poopy diaper, I don't want them to make a lot of noise, I don't want them to scream.” Now, they are quiet, and they either eat or they're attached to their iPads, and it's very pleasant. Very, very pleasant.

Melanie Avalon: Does one of them have a life-threatening allergy?

Cynthia Thurlow: Yes. My 16-year-old has peanut and tree nut allergies. If I had to pick a child to have a food allergy and I would not, of course want either of my children to have a food allergy, but he is by far the most conscientious of the two. And so, he navigates pretty well. Very responsible. Now, he's at the age where he can carry his own EpiPen, but I always have a backup. He navigates his carnivorish world really nicely. And so, when we travel, it's always the-- Let's hope it's the airline that doesn't serve peanuts as a snack.

Melanie Avalon: Are there airlines that still serve peanuts?

Cynthia Thurlow: Occasionally, I see that and I generally, when I get on the plane, I just politely ask. [chuckles] There is a person on the airplane that an aerosolized peanut could be a problem if you're on a long flight. I have never had a problem. People have always been super respectful of that, thankfully.

Melanie Avalon: What will set it off?

Cynthia Thurlow: Well, it's interesting. Every couple of years, they do RAS Testing, which is really looking at provoking the inflammatory response in the blood. And so, what's been interesting is that his results have never gotten better over the years. It's like in the hierarchy of nuts, it's like walnut, and hazelnut, and then peanut, and then almonds don't even register, but I just don't ever want to take the chance. And so, from our perspective, he's only had one confirmed contact with a tree nut, which was probably, I don't know, eight years ago, and he vomited violently, and had some wheezing, and it was all incredibly scary, and then, actually had a second exposure, even though we were really diligent when we went to a restaurant explaining what his allergies were. He had the whole like his lips started to tingle, and his tongue started to tingle, and then of course, we go down the rabbit hole of, “How far away from a hospital? Making sure we have the Epi Pen and trying to get things on board to help quiet the inflammatory response, the histamine response,” and it's scary. 

It's interesting because teenage boys are the most likely to trigger an anaphylactic episode because they think they're completely impervious to anything. Their frontal lobe isn't fully developed and I worry more about him when he starts navigating life outside of our house, and dating, and the exposures he can get there, and his allergies have never gotten better. When we looked into peanut desensitization, he would have to do it for the rest of his life like you do a series of these immunological therapies and then it resolves itself, it's like forever, and he said, “I don't want to do that.” He's like, “I'd rather just avoid.”

Melanie Avalon: One of the last serving jobs that I had and this was in LA. It was at a really nice steak house and one of the managers had a peppermint allergy. They said, “You can't have peppermint.” My thing, as listeners know and I might have told this story on the show before. I'm obsessed with my peppermint breath spray. I make it out of peppermint essential oil and water and it's like a thing on this podcast, by the way, people make it. We have links to the way I make it in ifpodcast.com/stuffwelike. I have this spray with me all day, every day. I use it all day, every day. I have an oral breath, fresh breath fixation. They said, “You can’t have peppermint” and I was like, “Okay, but I can have peppermints?” I was like, “It can't be that big of a deal.” All he did was use the peppermint spray while working and he had to go to the hospital. I was like, “Oh.” Then it was a running joke and they're like, “It's fine. It's not a big deal. This happens with new servers.” [laughs] I felt so bad. I felt terrible. I brought him the next day, massive gift of like, “Wine?” He's like, “I can't accept this.” I was like, “You have to. [chuckles] I'm so sorry.” So, yeah, that stuff can be serious. 

Cynthia Thurlow: It really can be. Had I not seen the impact as a nurse in the ER many years ago, I would never have understood how significant it can be. I just saw too many anaphylactic episodes. For anyone that's listening, this isn't familiar with that term. It's the most life-threatening response to an allergen and unfortunately, we're seeing more and more of this. Only 30% of kids outgrow their food allergies. It's a really small percentage. There're so many people navigating, young adulthood, and adulthood with food allergies. And so, yeah, it's surprising how the body can manifest exposure to specific allergens. It's really humbling quite honestly. Like, “Had I not had a child with a life-threatening food allergy?” I think my life would have been very different because it changed everything for me. I just didn't view the world as a safe place anymore. When I kept thinking like, “We could go anywhere, and he could get an exposure, and what's going to happen?” I don't want to be jabbing my two-year-old with an EpiPen. Obviously, I would have done it if I needed to. It definitely can be frightening as a parent and I think it's one of those things unless you've experienced it like you did with your boss, you probably can't even appreciate how significant it can be.

Melanie Avalon: Yeah. In a way, I'm glad that I had that experience, because I will really, really respect that going forward. Now, I'm just thinking, I bet in the future of healthcare way down the road. I feel they'll probably come up with something where they literally-- I understand that the allergy desensitization is this technique, but I wonder if in the future, there'll be a process where it literally just tells the immune system, “Hey, this isn't a big deal” like an instant shift. 

Cynthia Thurlow: I hope so. I just think there are a lot of families that are navigating. I know I felt fear and overwhelm even as a healthcare professional because my son’s allergist resounding words were, “Carrying EpiPen and pray.” I was like, “Who wants to hear that when they find out their two-year-old has life-threatening food allergies?” It's the last thing you want to hear. There're plenty of people that are hearing the same information from their allergist. Hopefully, there's something coming, there's some amazing, amazing immunologist, allergist out there that's going to revolutionize the way that we look at food allergies.

Melanie Avalon: I bet there is. Did you read Dr. Jason Fung’s, The Cancer Code?

Cynthia Thurlow:  I did.

Melanie Avalon: This was not allergies. But I feel the last part of his book had a really interesting information about immunotherapy for cancer, and just modulation of the immune system, and such.

Cynthia Thurlow: Yeah. It's interesting because it's such a departure from the conventional allopathic model that has been the norm over the last 50 years. I think Jason's brilliant and I'm so glad that he got people interested in having different types of conversations around cancer therapies because-- Did you interview? Why am I drawing a total blank, Sam Apple? 

Melanie Avalon: No.

Cynthia Thurlow: He brought back Warburg's research on the cancer model that is more aligned with Jason Fung’s book and was moving away from DNA-based or genetic-mediated types of cancers. He was a Jewish scientist in the midst of World War II and for some reason, Hitler took a liking to him and allowed him to continue his research. The book is really interesting. I'd love to share it with you.

Melanie Avalon: Wait, how old is he now? Because you asked me if I interviewed him?

Cynthia Thurlow: He's dead. Yeah, and then at Warburg-- Sam Apple is the author.

Melanie Avalon: I'm so confused about this timeline. [laughs] 

Cynthia Thurlow: Sorry. No, Sam Apple is the author and he's a research scientist. Yes, Warburg is the-- [crosstalk] 

Melanie Avalon: Oh, what is his book called? Does it the word Warburg in the title?

Cynthia Thurlow: I'm terrible with names. Melanie knows this about me. It's a struggle. I've been this way my whole life. Sometimes, I have these moments where I'm like, “I can't remember.” I can see the cover I’ll have to share it with you separately.

Melanie Avalon: Ravenous: Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection.

Cynthia Thurlow: It was very interesting.

Melanie Avalon: That sounds like a health page turner.

Cynthia Thurlow: Sometimes, a lot of times, Melanie and I, our podcasts overlap with guests and sometimes it doesn't. But I kept thinking, I was like, “I don't know if you've interviewed him.”

Melanie Avalon: I have not. There were some moments in Jason's book, where I was like, “Dah, dah, dah.” I was so invested. He does really nice reveals. The nuance that I didn't realize until reading his book was that the big paradigm shift that happened with Warburg was re-understanding because basically, the Warburg effect is the idea that cancer cells use-- They use glycolysis. They're running on glucose rather than fat. Jason talks about how they're actually-- it's not because they can't burn fat, it's because they're choosing to burn sugar, which is very interesting to me.

Cynthia Thurlow: Well, and you think about in the 1950s as Crick and Watson discovered the DNA Helix. That really shifted research in a totally different direction. And so, yeah, we're coming back to a principle that has been around for 80 years that largely had been left unrevealed, undiscovered, rediscovered, I had to think about.

Melanie Avalon: Hiding, I don't know.

Cynthia Thurlow: Hiding. Hiding probably because of the context in which that research was ongoing. 

Melanie Avalon: Oh, yeah, literally hiding. 

Cynthia Thurlow: Yeah. [laughs] 

Melanie Avalon: Well, for listeners, we'll put links to all of this in the show notes. And again, the show notes will be at ifpodcast.com/episode272. 

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Melanie Avalon: Shall we jump into everything for today? 

Cynthia Thurlow: Absolutely. 

Melanie Avalon: All right. To start things off, we actually have some listener feedback and this comes from Sarah. Sarah says, “I want to thank you. Several months ago, I got a CGM from NutriSense and I realized my fasting blood sugar was higher than it should be. The NutriSense dietician was encouraging me to eat breakfast earlier to help with high blood sugar in the morning. I just knew that couldn't be the answer. For months, I reached out to you, Benjamin Bikman, Cynthia Thurlow, and another doctor. I just couldn't figure it out. I heard your interview with Dr. Rick Johnson and that was so amazing. Then you guys talked about an interview with Peter Attia and David Perlmutter, and that was also amazing. I bought Nature Wants Us to Be Fat.” And for listeners, that is Rick Johnson's book. “Guess what changed. I started drinking more water and stopped eating dark chocolate with sugar at night. Well, I cut out all sugar, I also started taking vitamin C. That's it. I have lowered my blood sugars to the mid-90s. I couldn't be happier. This could have potentially been so bad down the road and so much harder to deal with.” So, that's some pretty cool feedback from Sarah. For listeners, I had Rick Johnson on the Melanie Avalon Biohacking Podcast. Cynthia had Rick Johnson on Everyday Wellness. 

I said last week that it was going to be this week, but I was incorrect in the lineup. Next week, Rick Johnson is actually going to be on this podcast. This is a really great teaser question for next week's episode. You definitely want to check it out, but Rick has some very, very interesting information surrounding the role of sugar, and fructose, and metabolic health, and in particular, Sarah was talking about some things that he talks about to help with all of that, particularly, the role of vitamin C. But super happy for you, Sarah that you're able to solve the issue. And also, I like the feedback about how-- because if you haven't a CGM from NutriSense, you do get to work with a dietician who can help you with your results, and what they mean and make suggestions. It's nice that Sarah was able to work with them, but also knew that for her personally, those suggestions weren't probably going to-- they weren't what resonated with her. So, I'm glad that she was able to find something that did work. Do you have thoughts, Cynthia?

Cynthia Thurlow: No, I think it really goes back to bio individuality the N of 1. The recognition that it may take multiple changes to your lifestyle to see some significant improvements. I'm sure the hydration and the reduction in processed sugars really made a big difference. One thing I want to point out that Sarah mentioned was that she stopped eating chocolate at night. And so, it's probably a good reminder, just to remind people that we have more insulin sensitivity during the day. If you're already leaning in the direction of insulin resistance or you're noticing your blood sugars are higher, you really want to be examining, like, how close to bedtime you're eating, what you're eating for your last meal, and sometimes, if you're deciding to have more discretionary carbohydrates, maybe easier and better to do that earlier in the day.

Melanie Avalon: Awesome, awesome, awesome. I think the vitamin C piece was because it lowers uric acid, I believe, I think that's the connection with that. So, again, listeners, tune in next week to learn more.

Cynthia Thurlow: I love Rick Johnson. I think resounding. I say to everyone, he's one of the most delightful interviews I've had easily in my podcasting career. He's just infectious everyone. That's my number two downloaded episode of the year. I'm not exaggerating.

Melanie Avalon: I should go and look at my stats.

Cynthia Thurlow: I'm very OCD about that. That's why some people come back multiple times. I'm like, “Your content really resonated and I need to bring you back.”

Melanie Avalon: I should probably do that. Yeah. I rarely look at the numbers. I probably should.

Cynthia Thurlow: I don't know. I'm very competitive with myself. It's like, I want to know each month that there are more people curious and interested and it allows me to see what content really resonates. Obviously, I think you're the same way. You wouldn't bring someone on The Biohacking Podcast unless you were super interested in them as an individual in their work, in their research. But it's always amazing to me, there are sometimes surprises, sometimes, I'm surprised by something will really resonate or other times, I'm like, “Oh, my gosh, this is the best interview” and then it doesn't get as much downloads. And so, I just find it all fascinating.

Melanie Avalon: I was just thinking about that because I was thinking about how people I bring back, it's honestly, it's based on who I really like. I know I've brought back some people that-- Again, I'd have to go look at the numbers, but my gut tells me they probably weren't necessarily the highest in the numbers, but I just really wanted to talk to them again. Yeah, it's an interesting balance. It's really fun. I think it's really fun like how we get to choose the lineup, really creating shows.

Cynthia Thurlow: Absolutely, absolutely. Speaking of amazing people that I know you've had on twice, I've had on twice. Robb Wolf, I could talk to. He's another person I could just talk to you for hours.

Melanie Avalon: Between the two shows, I think it's been, is it four? It's definitely three. He can come on anytime. I'll just have The Melanie Avalon Biohacking Robb Wolf Podcast.

Cynthia Thurlow: That's awesome. He's such a cool guy. He’s just so humble, down to earth, and just a great human.

Melanie Avalon: I know. Oh, and that was super fun. Cynthia and I both got to interview Mark Sisson last week and it was back-to-back.

Cynthia Thurlow: Yeah, we had an embarrassing kerfuffle on my end, which I'm grateful that I have a friend who intervened immediately, but there was a miscommunication between my podcast team member and what time Mark said he was available. And so, I was on the fly. [laughs] I think it turned out fine, but it was one of those things where you can't apologize enough when you're leaving someone at that level in their business wondering what you're doing. So, anyway, I think it'll all be fine. But still, it was a little embarrassing.

Melanie Avalon: Yeah, you and I talked about it right after it happened. I just would have been so flustered in my head, but I'm sure he probably didn't think about it nearly as much as you did.

Cynthia Thurlow: No, he's probably like amateur. I think it was fine. I agree with him.

Melanie Avalon: What's really interesting about him is, I was thinking beforehand, because I've been a follower of him for so long. I know Elle really well, I know his coauthor Brad really well, but I've never met him. I had an idea of what I thought he was going to be like and he was exactly what I thought he was going to be like, which was I thought he was going to be just really nice and just really, really energetic. Because I feel with people and interviews, everybody who I've had on has been so gracious and lovely. But sometimes, you get the sense that I thought with Mark, I didn't feel I was going to get any sense that this was out of his way or anything like that. This is what he does. I just thought he'd be all energy, and all in, and that's that was really the vibe I got, which was very inspiring, because I think he's 76? Oh, 67, 67. 

Cynthia Thurlow: 69.

Melanie Avalon: 69. Well, not 76. Sorry.

Cynthia Thurlow: Yeah, no. I was going to say, if he's 76, it looks pretty dang good. He was delightful and humble. I loved that. He is very committed to his family and the tail end of our discussion was about, how did you find balance with your family? Then he gave some really great insights and certainly, things I got off and I was just like, “Wow, the greatest gift you can give your loved ones is time.”

Melanie Avalon: Yeah, I love that. All right, shall we go on to our next question?

Cynthia Thurlow: Absolutely. This is from Sia. Subject is: “Help me please.” My name is Sia. I'm 41 and pretty sure I'm pre-menopausal. My thyroid is a tad off and I'm trying to correct that. I started fasting November 15th, and I started at 167 pounds, and here it is April 23th, and I weigh 162 pounds. I've always been a healthy eater, I switch it up with OMAD and ADF, and feel tired all the time. It's been hard to workout, I'm sure because of thyroid. I listen to your podcasts, and I've read your books and others from Dr. Fung. I know we're not supposed to compare ourselves to others, but I feel I'm seeing super slow results. Can you give me some tips or what your thoughts are? Sincerely, Sia.

Melanie Avalon: All right, Sia, thank you so much for your question. First of all, with the thyroid stuff, I'm super curious. This is a good thing to talk about just for listeners in general. The hypothyroidism issue can be a really tricky one to tackle and I think it's really, really important to work with a practitioner who's really knowledgeable in making sure they are addressing it correctly. By that, testing all the levels they need to be testing. The free T3, the total and free T4, the TSH, the reverse T3, Elle Russ has a really great book called The Paleo Thyroid Solution. For anybody who wants to get, I believe the most comprehensive overview of hypothyroidism, and what you need to be testing, and how diet affects it. I've been texting her this week about my own panel, because the doctor and I was telling Cynthia about this as well. I've been working with a conventional doctor on my-- because I have hypothyroidism and I'm on thyroid medication. This has been a whole experience just hitting home again, how important it is to take agency in your own health and your relationship with your doctor, and the labs that are being drawn, and stuff like that, because I've been working with conventional doctor for a while on my thyroid and I was working with her, because I found her within my insurance plan, and she actually was open to testing everything, and what she was prescribing me was what I also thought I should be on, and I was feeling good. 

But actually, the most recent time around, she changed my dosage. I was telling Cynthia about it. But basically, it was incorrect. The way she changed, it didn't make sense math wise for what she was trying to do. All of that to say, I'm all over the place right here. But I think it's really, really important to work with a practitioner who really can help you. I'd be curious, Sia, when you say, it's off. I'm wondering in what regards it's off. Is it what are you low in, how are you addressing it, is it with the medication and how is that being adjusted? And then all of that to say, but I'm super curious to hear Cynthia's thoughts on this. But if you're struggling with hypothyroidism and this issue, it sounds you're doing a lot of fasting and I probably would not be doing all of that fasting, especially like the ADF. What are your thoughts?

Cynthia Thurlow: Oh, I have so much. For full disclosure, Sia, I also have hypothyroidism, probably have Hashimoto’s, but I've never had positive antibodies, probably, because we're gluten free. There's a lot that I think about. When someone's in perimenopause and we're talking about hormesis, which is this hormetic stress in the right amount at the right time, there are a couple things that I think about. You mentioned that your values are off and I don't have a sense of what your labs were, but we have to think comprehensively. We have to think about what's your sleep quality, are you exercising, are you eating an anti-inflammatory diet? We know with an autoimmune issue you really have to work on gut health. I don't know, if you're just on synthetic medications like Synthroid. And if you are, that's totally okay, that's synthetic T4. But if your body can't actively convert T4 to the active form of thyroid hormone, which is T3, that could explain why the way the scale isn't really budging and why you're so tired. 

But the fact that you're so symptomatic, you're very tired. That should be a clue that you need to back up the bus, I would stop doing this really long fasts because in and of itself that is a stress to the body. I would absolutely positively work with a thyroid specialist, whether that's an endocrinologist, an integrative medicine, or an open-minded primary care provider, and make sure that they're looking at cofactors. I would ensure they're looking at iodine, and magnesium, and zinc, and your B vitamins, and looking at inflammatory markers. I see a lot of women that in early perimenopause are becoming insulin resistant and it could very well be. It's a combination of multiple factors that are contributing to why you feel so poorly. Weight loss resistance is more often than not, because of multiple factors. It's not just one factor. I think this really speaks to doing more digging. I would imagine it is not just your thyroid. It could also be adrenals, it could be low progesterone in relationship to estrogen, it could be your sleep quality. Don't give up hope, you just need more information, and I would absolutely positively back off on those long fasting windows. There's just no way you're going to be able to get in enough protein in one meal a day to be able to properly feel your body at this point. It sounds the fatigue is what you really need to use as your gauge. You can do fasting when you're not quite so tired. Then, it might just be that you start with a 12-hour window of not eating and slowly opening that up. But I really do fervently believe that you need more information. 

I love Elle’s book. Elle is a fantastic resource. I also think about and I'm turning my head to look, because I have a bunch of thyroid books. I actually did a reels on this talking about my favorite thyroid resources. We'll put the list of books that I generally recommend. I've got four or five. But I think Elle Russ' book is an excellent first choice to help educate you. She's all about empowerment and she really comes at it from the perspective of she suffered for years because she was navigating a world in which they weren't looking at the full picture. I think it's important to really understand, like, a full thyroid panel is a TSH, it's a free and total T3 and T4, it's a reverse T3, its antibodies. You can split hairs beyond that, but it really is important to have all those factors. If you're on medication that is not supporting your body adequately and you're not getting the right labs, not the errors on your part, but the practitioners are not ordering the right labs, it may not illuminate what is going on and giving you the full picture. So, good luck and definitely keep us posted.

Melanie Avalon: I actually emailed my doctor and I sent her, I was like, I don't know how she's going to take this, but I sent her a really long thing. I tried to approach it to her as not me saying like, “This is the way it is,” but saying like, “Oh, I'm curious about this. What do you think about this?” It was resources surrounding-- A discussion we had been having, because her concern, for example, and Elle was telling me about how this is such an issue is. Oftentimes, when people are on thyroid medications, if they're on T3 medication, it can or it should in a way suppress their TSH. And so, doctors treat to not lower the TSH, and so, then they can possibly keep patients in a hypothyroid state when arguably the TSH should be lowered when you're on T3 supplementation. So, that's a little bit of a nuance and I don't know if it's relative at all to Sia’s situation, but it could be something to consider for people. 

Cynthia Thurlow: I think it's really hard. I have to be honest I have functional training and I can tell you that if I had not been seeing an integrative medicine provider at the time of my diagnosis, I probably would have been left floundering for a few years. There are still individuals that are open-minded. I know Melanie works with someone who takes insurance that's open-minded. These unicorns do exist. Another resource that I generally direct people to is www.ifm.org, where you can look for practitioners in your area that have functional medicine training and tend to be a little bit more open-minded. I certainly have done a lot of podcasts with thyroid experts, some of whom are clinicians. Recently, it was Dr. Amie Hornaman is one. I know she works throughout the United States, I think about Dr. Eric Balcavage, who's wonderful and has a new book coming out. I think about Elle and there's someone else that we have scheduled for the podcast that's coming out this fall. But there's definitely a lot of resources. Dr. Amy Myers has a lot of resources online. Like I mentioned, I will make sure that we put it in the show notes. Some of the books that I give like a stepwise progression, because I probably have every book that's out there on thyroid. The ones that I think that I reference the most for patients, the Elle’s book is a great, first step for sure.

Melanie Avalon: Awesome. Again, we'll put links to all of that in the show notes and the show notes have a full transcript as well. All right, so, the next question, actually, the good question to piggyback on that. This comes from Gab and the subject is: “Podcast question.” And Gab says, “Hi, I have PCOS, hypothyroidism, and Hashimoto’s. My Hashimoto’s antibodies have gone down. So, it feels I'm mainly dealing with hypothyroidism and PCOS now. I love eating keto because it finally makes my chronic inflammation go down, my bloating has resolved, and I don't feel as swollen. However, I feel very restricted and limited with the way I'm eating and I'm still not losing fat. I have a huge laundry list of food sensitivities and allergies due to my Hashimoto’s, and I've been feeling so much better after staying away from all the foods that came back reactive from the test. I do take HCl and digestive enzymes along with one berberine a day at my meal, which is always in the evening. Melanie and I are very alike. My eating window is later at night. 

I'm in a bittersweet spot. The information of knowing my trigger foods for sensitivities is helpful, but now, I feel I have to eat this careful and clean forever just to feel okay. I'm trying to lose six to 10 pounds and the fat won't come off. I'm only 5’1”. Even two pounds is very noticeable for me and physically uncomfortable. I've heard you talk about this before on, “what exactly is the body running on if carbs are low?” I stay away from all processed foods and PUFAs, and I've been doing protein-sparing modified fast days here and there. My fat is also not high because I know eating high fat can stall fat loss. Nothing is working. The stubborn fat I'm trying to lose is on my arms and thighs. What is going on if my body is not using fat stores as fuel and energy, what am I running off of then? I'm in no way eating at a calorie surplus and I'm definitely not eating enough to maintain either, yet, here I am maintaining or gaining. Am I just doomed because of my hyperthyroidism? I'm finally on a medication that is starting to make me feel a little better each month. I take LDN, a B complex and I am constantly searching supplements and protocols. I take magnesium and CBD at night etc., etc. I do Pilates, lightweight training, walking, and yoga. When I used to do heavier weights training, I bulked up. This is probably due to my PCOS and the fact that I am testosterone and DHEA dominant. I know this probably means cortisol is my root issue. 

Does this mean my body refuses to lose fat because I'm running off cortisol? My body feels best when I'm doing low impact workouts and walking. It still is infuriating because I'm not eating enough and I know starvation mode is half myth, half reality. But you said it best on one of your pods, “you just can't gain fat if you're not eating enough to gain.” I've heard high insulin could also cause fat retention, but my insulin isn't a problem. I got a NutriSense CGM sent to me. I'll be setting up that soon to see what's happening. Please help. I feel hopeless, and helpless, and that my metabolism is permanently shut down. I love you both and I've been binging both of your podcasts. No pun intended. I'm losing my mind. I just want to lose the last pounds of fat, but nothing I do works.”

Cynthia Thurlow: Oh, Gab, I have to tell you. When I read this before we got on today and then listened to Melanie share your podcast question, you need to give yourself some grace. I sense that you're really, really hard on yourself and I don't know how long you've been on this journey. I think that sometimes when I sense that patients are really frustrated, we have to really simplify things. There is the power of our minds and I think that we have to look at things from different angles. When we're talking about weight loss and it's something we want really badly, I always remind people that we have to get our bodies better balanced in order to lose weight. I know that that's very often. The point of frustration that people as an example will come to me and say, I want to lose weight, but really, it's all the other things going on. I don't know how long you've been fasting, I don't know if you're doing OMAD, you've mentioned several times in this question that you are concerned you're not eating enough. The concept of your body perceiving that there's not enough food coming on board can absolutely positively-- negatively impact your metabolism. 

I think that we have to be very, very clear that if you're eating at a caloric deficit all the time, and you've got thyroid issues, and you've got some PCOS, and you've got food sensitivities, and you're being really strict with your nutrition, and you're doing this exercising, it tells me that there's a degree of intensity that needs to first be backed off of, but I don't know your age. So, I don't know if you're still in your peak fertile years or you're in perimenopause or menopause, but there's a lot to unpack. I think it really needs to really reflect on simplifying your program, because this degree of intensity is telling me that you're putting your body under an incredible amount of stress, whether you recognize it or not. If you're in the hierarchy of hormones, as I know, Melanie's talked about and I've talked about a lot on podcasts. If cortisol is up, glucose is going to be up and your body is really going to struggle on a lot of different levels. When I work with PCOS patients, yes, sometimes they do very well with a 12-hour, 13, 14-hour period during the day where they're not eating and maybe they do well on low carbs. So, it doesn't mean everyone does well. 

I had Dr. Sara Gottfried on recently and I know Melanie also recently interviewed her. She talks a lot about that there are women, who due to their own genetic makeup do need some degree of discretionary high-quality carbs in order to get that proper T4 to T3 conversion, so, inactive to active thyroid hormone. I think there's a lot here to work with, but I think you also need to start giving yourself some grace. I don't say that to be flippant or unreceptive, because I've been that person, the scale was stuck, and I was frustrated, and I'm not a very tall person. I'm only 5’3”. So, I completely understand that. But at one point and certainly with myself personally, we had to level the playing field and start over and it may be that you need to back off on the intensity of what you're doing. The last thing that I just want to add is depending on how old you are, Melanie is a very young, metabolically flexible woman. Melanie can eat late into the evening and it works for her. But I find for women as they're getting closer to middle age, and certainly, I'm 50. I'm at a different life stage. That doesn't work as well. We know we're less insulin sensitive during the evening and that might be another reason to reflect on when you're eating, what you're eating, and being a little bit kinder to your body. Lean into the lifestyle, give yourself some grace, maybe there's value in working with a practitioner who's going to be able to look at a whole system as opposed to just one issue related to having an underactive thyroid and PCOS. But all these pieces of the puzzle will fall into place eventually. 

Melanie Avalon: Yeah, I thought that was an incredible answer. I could not have said it better. I have quite a few thoughts and they all are very similar and echo what Cynthia said. It's a really good question. You keep asking, if you're literally not eating enough to maintain or gain, how are you maintaining or gaining? That's a reality where if you are maintaining or gaining, you are eating enough to maintain or gain, but it might not be because you are eating a lot. It's more likely the hormonal system that your body is in, and it's learning how to adapt, and how to deal with what you are taking in. It can feel like, no matter how much you restrict, your body's going to just maintain at that or you're saying gaining. It's really, really interesting, especially the more I learn about, the book I'm reading right now, I'm really excited. I'm going to be interviewing-- Do you know Ari-- Is it Ari Whitten?

Cynthia Thurlow: Yes, he's on my schedule.

Melanie Avalon: Okay. Are we both for his Eat for Energy? Have you read the book, yet? 

Cynthia Thurlow: Mm-mm.

Melanie Avalon: I’ve just started it. A lot of it is talking about the mitochondria and it's just making me realize more and more how-- Because the thesis thus far, I just started the book. But the primary thesis is that chronic fatigue and all of these health issues really the root of them is in the mitochondria. If the mitochondria are not producing energy or shutting down their energy production, we're going to have all of these experiences. That's a very hormonal thing. The mitochondria not producing as much energy as they should be, that's what they're doing because of the environmental stressors that they are exposed to. That's a language of your body and that's why the answer, I believe is and Cynthia said this is, in a rebalancing. The answer is likely in a more broad lifestyle shift change and all this rather than-- because you say that you're looking for supplements, and trying all these different things, and the answer probably is not there. I am really curious to see what you learn with the NutriSense CGM. That might be helpful seeing how your blood sugars are reacting to things. I did want to comment on that you say you know that you don't have issues with insulin. I'm wondering how you know that, especially if you still have active PCOS that is often linked to insulin. I would find it interesting if your insulin is great and you're experiencing all these issues and have PCOS. That would seem a little bit like an anomaly to me. I do wonder if maybe insulin is still high for you. 

But going back to the dietary approach, because it sounds what you're doing is, you really want to be doing keto, and you're doing a very restrictive, it sounds like a low-fat version of keto, and it doesn't seem to be working. There are two big paradigm shifts that I would suggest trying. One would be going higher fat on the keto, but adding those fats from C8 MCT oils. Basically, eating what you're eating now, but adding in a- This is just something to try. I'm not saying this is necessarily the answer, but if you add in a lot of fat from C8 MCT oil, you can stay in this keto state that you want to be in, and that's a very metabolic fat, and that it stimulates energy production. It can really stroke your metabolism and it itself is not easily stored as fat. It might be something that can give your body a signal of abundance while supporting a fat burning state. It's just something to try. 

Option number two and Cynthia touched on this going on a higher carb approach. We've had a lot of people throughout the years reach out to this show, who have been doing low carb. They're just wedded to low carb and they just you know are convinced that keto is the only way that things are going to work. We've suggested or I've suggested trying actually-- I know Cynthia was talking about Sara Gottfried’s approach, which is still a ketogenic approach, but with more carbs. But I would also like to suggest that and/or an actually high-carb approach. A lot of people switch to a high carb, low fat approach still Whole Foods based, still high protein. That is like the thing, I can't tell you how many people I've suggested this to and then they reach back out and say, “Wow, I got my energy back, I started losing weight again.” That's something to try. I know it can be really scary, especially, if you are scared of carbs, but it's something to try. To clarify, I like with the high carb doing a lower fat approach, because then you're not hitting your body with fat and carbs at the same time in a high amount, which I think for a lot of people does not work that well for metabolic health. Yeah, those are just some of my thoughts. Any follow up thoughts?

Cynthia Thurlow: Yeah, I think it's really the N of 1. It's definitely on this journey and there's no one size fits all. But I think if you're too fervently trying to move too many levers all at the same time, it's going to be hard to know what's effective and what has been helpful. But I think getting things back to a really simplistic methodology is the best starting point and just giving yourself grace because I know how frustrating it can be to be weight loss resistant. I've now been there twice in my 40s and so, I think it's important to just understand that there's some imbalanced part of your system. If you look at your body as a system, there's something that's imbalanced that's creating this resistance. Once you figure out what it is, it will fall into place.

Melanie Avalon: And also, something to consider because we don't know what your weight is. It's also possible to evaluate the weight that you're looking to lose and I'm all for people wanting to lose whatever weight they want to lose, like, no judgement. People can do whatever they want. But the six to 10 pounds, are they the last six to 10 vanity pounds or are you coming from a higher weight? It might be that where your body is right now is a very healthy weight and losing those six to 10 pounds are going to be something that will be hard just because depending on what your weight is right now, they're not something that your body has any intention of losing because it doesn't perceive that as something that it needs to be if you're a completely normal weight or on the lower side of normal. So, something else to consider.

Cynthia Thurlow: Absolutely. But first and foremost, give yourself grace.

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Melanie Avalon: All right, shall we go on to our next question?

Cynthia Thurlow: Yes. This is from Christina: “Confused on eating in window.” “Hello, I'm so excited to start this journey with intermittent fasting. I am four days in and doing a 16:8. So far, it's been good. However, I feel I'm only cutting out breakfast and a snack. I'm a CrossFitter. So, I'm used to eating nonstop through the day. Sidenote, On break from CrossFit as I've been on and off since October, hello sinus season and weight gain. I've been having my normal lunch grilled chicken, broccoli, cauliflower, sweet potatoes, and red potatoes followed up with mixed nuts, snack, and then dinner which varies, but I try to stick to protein and veggies. I'm wondering if this is too much. I'm typically hungry by lunch. As for the snack I worry it's just out of habit. Any recommendations? I'm breaking the constant eating once I open my window. Also, I have now been craving pineapple listening to your podcast all day at work. So, I switched from nuts to a bowl of fresh fruit. Pineapples, strawberries, red grapes, cantaloupe, watermelon as of today. Thanks for the advice and looking forward to this journey.”

Melanie Avalon: All right, Christina, thank you for your question. I think you’ve answered your question when you asked us about-- Well, you said you're wondering if it's too much for the snack you worry, it's just out of habit. It sounds you have a pretty intuitive idea that the snack you're eating you're not actually hungry for. I don't want to put words in your mouth, Cynthia, but haven’t you talked before about how you are not a fan of snacks?

Cynthia Thurlow: I'm generally, generally not. I think sometimes, maybe we didn't have-- As an example, she's giving a good example of protein and some healthy carbs, and maybe she needed to add some fat to that meal to maybe keep her satiated, because she was going towards nuts. Whether or not, that's by habit or it's by her body just needing to feel they're fully satiated I, sometimes feel like, “If you're using those carbohydrates, it's fine to use a little bit of olive oil, or butter, or something that's going to keep that satiety.” I don't know, if she's just not getting enough nutrient density in that meal, obviously, that's a clean meal, but maybe there's not enough nutrient density there and that could be what's driving that. I know for myself personally, today, it was my first day back in the gym doing a heavy lifting day and I definitely am finding my first meal that I had was definitely there was more substance to it than on the day that I'm not exercising as fervently. CrossFit is intense. 

The other thing that I think about is, I don't know how young this woman is, but are you exercising for your menstrual cycle? Your follicular phase from the day you start bleeding up until ovulation, if you have a typical 28-day cycle, you can get away with more intense types of exercise. But if you're after ovulation closer to when you're going to start bleeding, your body's going to struggle a bit more. You're going to have more cravings for some carbohydrate rich foods, you may not be able to work out as intensely, and so really examining if you're still menstruating, where you are in your cycle to lean towards what will work best for you. 

The other thing is, if you look at people like Dr. Stacy Sims, who is anti-fasting, but does a lot of research in women's physiology and athletes. We're talking about a very small subsect of the population. Again, the menstrual cycle is important. Where you're training, at the level you're training is important to really be cognizant of how that's going to impact your recovery. Do you really want to be restricting food if you're training for something? Those are the things that come up in my head and definitely as listeners are leaving questions in the future, I would encourage them to at least give us some context like, “Are you 35 or are you 50? Are you 25 or are you 40?” Because that can help guide some of the suggestions that we make.

Melanie Avalon: Yeah. It sounds like if I'm reading it correctly, so, she's not doing any CrossFit right now. I think the issue is that she's used to eating a lot from doing CrossFit, but now, she's not doing CrossFit and so, she's wondering if this is all just habit from her CrossFit days.

Cynthia Thurlow: But she seems pretty intuitive. When people say, “I wonder if it's X,” they generally, probably already have a sense of what may need to be adjusted.

Melanie Avalon: Yeah, exactly. [chuckles] As far as it sounds you're eating the exact same amount of food that you're eating when you were heavily doing CrossFit, and now, you're wondering if it's too much. I know it sounds really simple, but you're asking how do you stop the habit of eating constantly the whole time. There's a magic to just creating some rules, some yes/no rules that you stick to and trying it. Rather than saying, “I'm going to eat my meal, and then I'm going to try not to have a snack, or maybe I'll have like a little bit of a snack,” and you could just say, “I'm not having snacks.” I know that sounds very simple, but it's approach that you can stick to. You can have your meal, and have it in a set place like in the kitchen, and then when you're done with the meal putting everything away, and then kitchen closed and no snacks, and even not having the snacks in the house, so that they're not accessible, and then holding yourself accountable, then having your dinner later. I think we can empower ourselves a lot more than we think we can if we just set up a rule that we say we're going to follow and then we follow it rather than trying to follow it, which is a nuance, a small nuance with language, but I think it makes a big difference. Shall we do one more question? 

Cynthia Thurlow: Sure. 

Melanie Avalon: All right. We have one more question from Michelle. The subject is: “Blood work” and I feel this is a really good question for Cynthia. Michelle says, “Good afternoon. I've been doing IF since March 28th, 2021 and I love it. I'm 39 years old and I'm having issues with bloodwork. My bloodwork is always good, but I've always had low iron. This past time, it was 8.6. My doctor encouraged me to really take my iron for three months and take ibuprofen a few days before my super heavy periods to decrease the flow. Taking the ibuprofen actually works. My last test, my iron was up to 12, but my sodium chloride and potassium were all off. Any ideas of what's going on? Could this be due to fasting? I use the sauna several times a week and I do hot yoga. I'm going to have it rechecked next week, but I wanted to see if anyone else had these issues. Thanks in advance,” Michelle. And now, Cynthia, now that I read this, I see what you're saying. So, thoughts on that?

Cynthia Thurlow: Yeah. Well, there's a lot here. I think Michelle is actually referring to her hemoglobin going from 8.6 to 12. It's definitely heading in the right direction. First of all, she's 39. This is perimenopause. When our bodies are heading towards 10 to 15 years out for menopause and our ovaries are producing less progesterone, so, we have this relative estrogen dominance, which can contribute to heavy menstrual cycles amongst other symptoms. That's number one. 

Number two, if she's doing a lot of exercise and she's doing the infrared sauna, you can absolutely lose discretionary electrolytes. I actually just did a podcast with the amazing Robb Wolf on this particular topic, because we get so many questions. And so, yes, you can effectively lose sodium chloride, magnesium, potassium with sweating. You can have renal losses in your urine. If you are not replacing the electrolytes after sauna and yoga, you absolutely need to be. In fact, I generally recommend that people are using electrolytes throughout the day, especially if they're fasting, but then you add in the exercise and all the extra sweating, and you need to replace not only the water that you've lost, but also the electrolytes. 

Couple of different things. This is perimenopause. Your heavy menstrual cycles will probably persist and continue. There's a lot of different ways to address that, but it sounds like relative estrogen dominance, but most importantly and the thing that I think will be most beneficial is to replace the electrolytes. I have a product called Simply Hydration that you can take in a fed or a fasted state and then, I love LMNT, Robb Wolf's product. My favorite is Orange Salt. I would say in our family, the next big flavor is Grapefruit, which unfortunately, they only have out in a limited amount. But those are definitely some options. You want to salt your food and you want to be making sure that you're staying ahead of those electrolyte losses. I don't know what your numbers were, so, they may just be suboptimal or if they were significant, I would imagine this healthcare practitioner probably would have sent you home with some recommendations. So, those are my thoughts. What do you think, Melanie?

Melanie Avalon: Yeah, I thought that was great. For listeners, LMNT is actually a sponsor on today's episode. I think it's in the pre-roll. You can listen to that to get a free offer and I think a discount on electrolytes. So, check that out. They just changed it. it’s some offer, but I think it's a discount. Yeah, regarding the iron, the hemoglobin, so, I have struggled historically with anemia and mine got very bad. Very, very bad. Mine got to four. I thought I was dying. The reason I bring that up is you're asking if it could be due to fasting. My historical struggle-- So, now, I very intensely monitor my iron panel. Its changes and its fluctuations have been pretty independent of my fasting experience. There are a lot of potential causes and your doctor, hopefully, talked to you about this. But there are a lot of causes for anemia and the inability to keep up your hemoglobin or keep up your ferritin, which is a storage form of iron. It can be internal bleeding, which is what they thought it was with me because mine was so severe. It can be absorption issues, just not being able to absorb. People with celiac often have this issue. You could have normal iron levels, but not have ferritin, because your body is not converting it to ferritin or hemoglobin is just not building up. I'm actually about to read a book. I'm really excited. Do you know Dr. Morley Robbins? 

Cynthia Thurlow: I’ve heard of him.

Melanie Avalon: He wrote a book called, I think, Cu-RE. I haven't read it yet, but he's going to be coming on my show and apparently, he talks all about the copper-iron relationship and that whole role. I think at least, a reason that the body struggles so much with iron is because it's actually a very inflammatory compound. It's ironic because we need it. It's vital to our life. We would be dead without it. Like I said, I literally felt I was dying when I was that anemic. It does create oxidative stress, it's inflammatory, it can potentially feed pathogens. The body is very, very intense in regulating it sort of like a blood sugar, how blood sugar can be toxic, so the body's really intense about regulating that. There are so many places that things can go wrong. [chuckles] Like, where you're getting it from, where you're absorbing it? All of that to say, I don't believe the fasting is the cause of that. It's probably something else and it's probably something where you really need to work with a knowledgeable practitioner to find the root of it. 

I will say what's worked for me for keeping up my iron, actually, I know you're really good friends with her, Dr. Cochrane? Are you friends with Teri.

Cynthia Thurlow: Yes, very good friends.

Melanie Avalon: She made the suggestion to supplement with chlorophyll to boost iron and I found that really helpful. I also supplement with grass-fed spleen that has the highest amount of heme iron of basically, any animal product that you can get. I currently use ancestral supplements. If I make my own organ supplements down the line, I definitely want to make a spleen one. But that might be something to try. I can put a link in the show notes. I have a discount code for them, I think. But yeah, the iron one is tricky. So, really quickly do you have thoughts on her taking the ibuprofen for the periods?

Cynthia Thurlow: I know that it helps with prostaglandins and I think that's part of it. When I read that, I was like, “Oh, she's estrogen dominant.” And so, until you address that, that persists and then it goes into the synthetic hormones, and IUD, and ablation, and hysterectomy. That's what's coming for her, unfortunately. That's the allopathic model. I managed to get through perimenopause without any of the above. I'm happy to say, “Thank God.”

Melanie Avalon: Congrats. All right, well, hopefully, that was helpful, Michelle and definitely feel free to update us with anything. This has been absolutely wonderful. A few things for listeners before we go. If you would like to submit your own questions for the show, you can directly emailquestions@ifpodcast.com, where you can go to ifpodcast.com and you can submit questions there. This was definitely an episode where you want to check out the show notes. We had talked about so many things. Everything as well as a transcript will be at ifpodcast.com/episode272. And then you can follow us on Instagram. I am @melanieavalon, Cynthia is @cynthia_thurlow_ and we are @ifpodcast and definitely tune in next week. Again, I mentioned it before, but Rick Johnson will be our special guest next week. And Cynthia have fun on your travels.

Cynthia Thurlow: I will. I'm so excited. It's hard to believe the past two years, we have not been back to Europe. And so, we are headed to the Czech Republic, and we start in Prague, and end up in Budapest. So, I haven't been to Eastern Europe with my kids. I'm super excited to unplug with them.

Melanie Avalon: I'm really excited for you. You deserve it after all of the book launch. You're coming out of like the storm. 

Cynthia Thurlow: Oh, yeah, that's a whole conversation in and of itself. I'm like, “I'm burned out, I need a break.” So, I'm super excited. But in my absence, I know everyone will love hearing from Rick, who I put on a pedestal.

Melanie Avalon: I know. It'll be great. All right, I'll talk to you in a few weeks then. 

Cynthia Thurlow: Sounds good. 

Melanie Avalon: Bye. 

Cynthia Thurlow: Bye. 

Melanie Avalon: Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and recomposed by Steve Saunders. See you next week.

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Sep 12

Episode 230: Reversing PCOS, Body Fat Percentage, Measuring Glucose, CGM Vs. Glucometer, Fasting Insulin, Meal Timing, And More!

Intermittent Fasting

Welcome to Episode 230 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Gin Stephens, author of Delay, Don't Deny: Living An Intermittent Fasting Lifestyle

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Listener Q&A: Dana - Meal Timing During Eating Window

TRANSCRIPT

Melanie Avalon: Welcome to Episode 230 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Gin Stephens, author of Fast. Feast. Repeat.: The Comprehensive Guide to Delay, Don't Deny Intermittent Fasting. For more on us, check out ifpodcast.com, melanieavalon.com, and ginstephens.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment. So, pour yourself a cup of black coffee, a mug of tea, or even a glass of wine, if it's that time, and get ready for The Intermittent Fasting Podcast. 

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One more thing before we jump in. Are you fasting clean inside and out? Did you know that one of our largest exposures to toxic compounds including endocrine disrupters, which mess with our hormones, obesogens which literally cause our body to store and gain weight, as well as carcinogens linked to cancer is actually through our skincare? Europe has banned thousands of these compounds for being toxic, and the US has only banned around 10. It's honestly shocking. When you're putting on your conventional skincare and makeup, you're likely putting toxic compounds directly into your body. These compounds can make you feel bad, can make it really hard to lose weight, can affect your hormones, your mood, your health. And ladies, if you're thinking of having kids, when you have a child, these compounds actually go directly through the placenta into the newborn. That means your skincare and makeup that you're putting on today actually affects the health of future generations. Did you know that conventional lipstick for example often tests high for lead, and the half-life of lead can be up to 30 years in your bones? That means when you put on your lipstick, 30 years later, half of that lead might still be in your body. 

Thankfully, there's an easy, easy solution to this. There's a company called Beautycounter and they were founded on a mission to change this. Every single ingredient in their products is extensively tested to be safe for your skin, you can actually feel good about what you put on. And on top of that, their products actually work. That's because they're not “all natural.” They actually combined the best of both worlds, both synthetic and natural ingredients, to create products that actually support the health of your skin and make your skin look amazing. They have skincare lines for all your skin types, deodorant, shampoo and conditioner that I love, antiaging and brightening peels and vitamin C serums, and incredible makeup. If you see my makeup on Instagram, that's all Beautycounter. You can shop with us at melanieavalon.com/beautycounter 

And if you're thinking of making safe skincare a part of your future, like we have, we definitely suggest becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders and a welcome gift that is worth way more than the price of the yearlong membership, totally completely worth it. Also, definitely join my clean beauty email list at melanieavalon.com/cleanbeauty, I give away a lot of free things on that list and join me on my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. I do a weekly giveaway every single week for Beautycounter, people share their experience and product reviews, and so much more. And again, the link to shop with us is melanieavalon.com/beautycounter. All right now enjoy the show.  

Hi everybody and welcome. This is episode number 230 of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Gin Stephens. 

Gin Stephens: Hi everybody.  

Melanie Avalon: How are you today, Gin?  

Gin Stephens: I am fabulous.  

Melanie Avalon: Why are you fabulous? 

Gin Stephens: Well, I'm at the beach but I haven't had a chance to enjoy the beach yet, because I've been working so hard, trying to move stuff from the house to the condo and the condo to the house. And Lord, it's like I'm moving. I mean it's moving. I've been working really hard. Such a good workout. I am, of course, doing it all in the fasted state. And, yeah, I've used all my muscles. Today, I had something funny happened here at the house. I was trying to change a lightbulb in the ceiling fixture in the bathroom because I had two lightbulbs in it and I noticed one of them was out and I was just going around doing things. You know how you unscrew like the little metal at the bottom of the glass dome and then the glass dome comes off, then you change the lightbulb and you put that back on and screw it back together? 

Melanie Avalon: Yes, I always get scared when I do it.  

Gin Stephens: Well, you should be scared because today, the beach, everything rusts at the beach. I was unscrewing, unscrewing, unscrewing, unscrewing, and actually, I wasn't unscrewing the little nut that holds it together. It was unscrewing the entire light fixture. So, the whole thing came out. It was just dangling there by the wiring. I'm like, “Okay, this is interesting.” So, [sighs] long story, I went all around, the people at Lowe's, they were great. The guys were like, “Alright, let's try spraying this stuff on it,” they went over-- and anyway, they couldn't get it apart. I was just going to buy like a new piece, but apparently you can't just buy a new piece. So, they sent me to this hardware store, and the guy had this vise and this equipment and he managed to unscrew the rusted unscrew. I came back and put it back together.  

Melanie Avalon: Good job.  

Gin Stephens: I know, I felt so accomplished. And I put in LED lightbulbs, and they're supposed to last for 10 years. So, 10 years from now, I'm just going to call an electrician to come and put a whole new light fixture in. This light fixture is now abandoned. [laughs] Anyway, I felt so good that I did it. But people are so helpful. 

Melanie Avalon: I always get scared screwing in the light bulb because you don't know if it's on. So, I like screw it in and I hold it really far away. I know I could just unplug the unit, but normally I don't want to do that. Do you know what I'm talking about? I hold it really far from my face and I squint and I screw it.  

Gin Stephens: Yeah, I'm not even worried about screwing in a lightbulb to a light fixture because you're not touching the metal part. 

Melanie Avalon: I'm always scared is going to pop or something because that's a good question. Maybe that's why I'm scared. Maybe it happened once.  

Gin Stephens: I wouldn't worry about that.  

Melanie Avalon: I've definitely had it pop while holding it in my hand and it scares me. 

Gin Stephens: Okay. Well, I'm not scared of lightbulbs, but I'm now terrorized about-- and then the other bathroom, the light bulb in there, I can tell it's got two lightbulbs, and one of them needs to be changed because it's not on. I was like, “Well, let me just try to unscrew the bottom of this one just and see.” No, it wouldn't even turn on, I'm like, “Forget it.”  

Melanie Avalon: All of them are like that.  

Gin Stephens: Everything at the beach gets rusty. It is true. It is a different kind of place. 

Melanie Avalon: Can I make a confession about lightbulbs?  

Gin Stephens: Sure.  

Melanie Avalon: In middle school, I think, probably my biggest crush of-- what's it called, like grade school years? 

Gin Stephens: Elementary school? 

Melanie Avalon: Like pre-college. What do you call all of it collectively? 

Gin Stephens: K-12?  

Melanie Avalon: Is there not a word?  

Gin Stephens: I'm not sure what phase you're talking about, like what part of it? 

Melanie Avalon: Kindergarten through 12th grade. What do you call that? 

Gin Stephens: Just K-12. We just say K-12.  

Melanie Avalon: K-12 means all of that?  

Gin Stephens: Yeah, from kindergarten to 12th grade. We usually distinct it by what phase of it. 

Melanie Avalon: You think there'll be one word that means elementary school, middle school and high school.  

Gin Stephens: Yeah, we just usually say K-12.  

Melanie Avalon: Okay, well. 

Gin Stephens: I'm a teacher, so I'm like, “What is the word? There's got to be a word. Why am I not thinking of the word either?” I don't know. We just say K-12, because we usually just break it down more. We've got undergraduate, that's college, but I don't know. 

Melanie Avalon: But I don’t want to break it down. My biggest crush from that entire K-12, yes. [laughs] I've never heard the phrase, K-12. Okay, my biggest crush from K-12, I'm just going to say it, his name is Jordan Watts. And me and my friend Emily Stock-- Oh, I don't know if I should say names. I know she listens to the show.  

Gin Stephens: I think it's fun to say names.  

Melanie Avalon: Okay. [laughs] I know she listens to this show.  

Gin Stephens: I haven't heard the story yet, though.  

Melanie Avalon: Okay, well, I know she listened to this show, because she wrote in once. And I was like, “Wait, Emily? Is this Emily?” Emily, if you're listening, I hope you don't mind me sharing this. We were obsessed with a boy whose last name was Watts, and we called him Lightbulb. And we would just call him Lightbulb and draw lightbulbs.  

Gin Stephens: That was the code name for him, was light bulb? 

Melanie Avalon: Yeah. Whenever I hear lightbulb, I think of that. 

Gin Stephens: Well, that's funny.  

Melanie Avalon: I think he's married now. 

Gin Stephens: Good times. It's been a very lightbulb day. I also changed on all the halogen lightbulbs in the house because, Lord, they're hot, halogen. They're so hot. We had undercounter lighting that were halogen the you stick in with the little pins, and the plates in the cabinets were hot, because the halogen lightbulbs were so hot. I found these LED replacements that worked, also at Lowe's. Lowe's is amazing. I just wander around Lowe's and ask the people that work there to help me do things and they're great. I'm like, “Hey, I don't know what to do. I have this, I need something else, help me.”  

Melanie Avalon: That's what I do.  

Gin Stephens: Yeah. And they're awesome, they're so helpful. 

Melanie Avalon: I really recommend that color-changing lightbulbs.  

Gin Stephens: I don't want any colors.  

Melanie Avalon: That's how I make my whole room red and pink at night.  

Gin Stephens: I just like normal colors. I want it to just be light.  

Melanie Avalon: But then, you can make your whole evening no blue light.  

Gin Stephens: Yeah, I'm not going to do all that.  

Melanie Avalon: Honestly, it's probably one of the best changes I've made in my apartment for my sleep. 

Gin Stephens: I've got a lot of rooms in my house, and we go from room to room. That would be a lot. 

Melanie Avalon: Actually, I just put them into two of my lamps, and so at night, I just turn on those two lamps and they're pink.  

Gin Stephens: Okay. 

Melanie Avalon: And then, I turn on my Joovvs.  

Gin Stephens: So, you’re lighting your way with the Joovv?  

Melanie Avalon: Uh-huh. It's great. 

Gin Stephens: I know that all your photos on Instagram are always pink. The light is glowing. [laughs]  

Melanie Avalon: I like the glow.  

Gin Stephens: Anyway, I'm like a home improvement girl. So, I could totally do that. I could do anything. I could put in-- 

Melanie Avalon: You could. I support.  

Gin Stephens: It's amazing what you do when your husband is not here, because Chad would have handled all that. [laughs] He would have been the one, like, “Why is this broken?” Instead, it was me. 

Melanie Avalon: I always get really proud of myself when I fix something that would have been fixed by my dad. And I'm like, “Oh, look at my new skill.”  

Gin Stephens: Exactly. We can do it.  

Melanie Avalon: Because when you're a kid, you're so in awe of how your parents know how to do everything, and then you realize it's just because you acquire these miscellaneous skills over the years. 

Gin Stephens: Well, and watching the people that come, and when we're having the work done in our house and the people that work for the companies that are doing these things, I'm like, “They don't have a magical skill set. They had to learn how to do it.” I'm as smart as them. I can do it. If they can learn how to screwing a light fixture, I can learn how to screwing a light fixture. Although the guy at Lowe's was hilarious, the guy in the lighting section. I was talking to him about how I couldn't get it apart. He's like, “Well, I don't really know. I'm not an electrician.” I said, “I think unscrewing this from this nut is not really electrical work.” [laughs] Most of it is just finding the parts that go together and put them together. Anyway. 

Melanie Avalon: Fun times.  

Gin Stephens: It was. It's been fun, but I'm ready to be done. My friend, Michelle, is coming to visit me on Thursday. So, trying to get all the work part done. So, then we can relax.  

Melanie Avalon: Very nice.  

Gin Stephens: Yeah. What's up with you? 

Melanie Avalon: Yesterday, I was on Brad Kearns podcast. It's always surreal when I go on those show. He coauthors all of the books with Mark Sisson, like all the Primal Blueprint books, and The Keto Reset Diet and all of those books, and he cohosts Primal Blueprint Podcast with Elle Russ, and I've been on that show. But I don't know, I feel it's moments like those where I'm just like, “I've come a long way.” The reason I really feel that is because I'm super excited to be on it, but it's not this huge thing. In the past, myself 10 years ago would have been freaking out about any of the individual interviews I have now. And it's just like, “Oh. I'm just showing up.” 

Gin Stephens: Yeah. I was just on the radio, and I didn't even tell anybody. It's at the point where I'm just doing, it's just so routine. You're not like, “Oh, my gosh, I'm going to be on the radio.” 

Melanie Avalon: Yeah. I don't want to make it seem I'm complacent or that I take it for granted, I don't at all. I realize when I have these moments how far I've come and how the barometer has changed for my goals. 

Gin Stephens: This is our job. Our job is talking to people on different media outlets. It's just making that shift to like, “Yeah, this is what I do. I talk to people for other people to listen to.” My elementary teachers, all of my K-12 teachers, in fact, to pull out that K-12 again, they knew I was going to do something with talking and here I am. 

Melanie Avalon: Yeah, here we are.  

Gin Stephens: Talking for our living.  

Melanie Avalon: Now, the goal is the TV show. I would like to be at a place in the future where I'm just showing up for my TV show, and I'm like, “Oh, just another day.” 

Gin Stephens: Just another day on your TV show. Yeah, fabulous. I hope you get a TV show. I do not want a TV show. Although I do think that Clean(ish) would make a great TV show.  

Melanie Avalon: I agree.  

Gin Stephens: I've never wanted to be on a TV show, but I'm a teach her, I can do it. But I think it would be a great TV show like Marie Kondo went around and helped people, say, “I love you.” “Thank you for serving me,” to the things that we're getting rid of, or whatever.  

Melanie Avalon: Or it could be a docuseries.  

Gin Stephens: Well, that's true, but I would like to go into people's homes and help them. That's the way I was picturing it. See, I am more like, “Let me help you figure out your house.” I don't want to do a docuseries, that is a big no. Like an expose, kind of thing, like, no. 

Melanie Avalon: No, docuseries is, it's like a documentary in a TV show format. 

Gin Stephens: Well, I know. I know what it is. But we're talking about the issues, like the science behind it, I don't want to do that. You can do the docuseries, that's your boat. You go sail on the docuseries boat. I want to help people look at what's under their cabinets. I'm like in the nitty gritty. That's me. I'm at the application phase. [laughs]  

Melanie Avalon: We could do a lot of TV shows between us.  

Gin Stephens: We could. You do the science part. I like the science part. I understand the science part, but I don't want that. I don't want to do docuseries. 

Melanie Avalon: Well, I really want to do a talk show. That's what I really want to do. Like the podcast now, but as a talk show with a live studio audience. Oh, I’ll be so excited. I could see the audience. 

Gin Stephens: I feel like I could do that because that's what teaching is. 

Melanie Avalon: Yeah. I would just love that. Okay, can I make a brief announcement?  

Gin Stephens: Please do.  

Melanie Avalon: So, last episode, I said that I had only briefly read the serrapeptase COVID study. So, I actually sat down and read the rest of it. I'm just in shock because this is my first time sitting down and actually reading extensively the literature on serrapeptase. It really is a wonder compound. I'm shocked it hasn't been taken by the pharmaceutical industry and made into a drug.  

Gin Stephens: Can they do that, though?  

Melanie Avalon: That's why I'm not sure. This is the way I think that they could. I want to put this out to the universe. But I feel if the pharmaceutical industry finds something that they normally can't make into a drug, because there are the rules about-- 

Gin Stephens: Because it's unpatentable. 

Melanie Avalon: Yeah. But I think what they can do is try to make studies to show that it's unsafe as a supplement, and then get it regulated that way, and then turn it into a drug. There's a conspiracy theory out there that that's what's happening right now with-- There's some compound that normally would be a supplement, but now all of a sudden, there are all these studies saying that it's unsafe. What is it? Robb Wolf actually had an episode all about this. It's NAC, so that's something that used to be you could just buy, but now the FDA is turning it into, I think, requiring prescriptions. I think that's the route that could be taken. It's interesting, because the article I was reading about serrapeptase and COVID, they're basically proposing that serrapeptase be made into a pharmaceutical to help treat COVID and it's published in a clinical journal. I'll link to it in the show notes, but they go into all the mechanisms of action, all of the different things that it could do, specifically with COVID and inflammation and with the mucus, and there's so many things it can do, but then beyond that just its anti-inflammatory potential, its antioxidant potential, and it really doesn't have side effects.  

From listeners, the biggest side effect I hear, some people get GI distress from it. It's hard for me to know if it's actually the serrapeptase or if it's the brand they're taking, but in any case, I am obviously a huge fan, but now I'm even more of a huge fan. For listeners, I will be making my own pretty soon. So, you can get on the preorder list and definitely get on the preorder list because the email list almost has the amount of people that we're going to do for the preorder. So, I anticipate the preorder is probably going to sell out. It's going to be a thing where like, when you get the email, you're going to want to jump on it. So, you can go to melanieavalon.com/serrapeptase, and that's how you get on the email list.  

Gin Stephens: Very cool.  

Melanie Avalon: Hi friends. I'm about to tell you how you can get free electrolyte supplements, some of which are clean fast approved, all developed by none other than Robb Wolf. Have you been struggling to feel good with low carb, paleo, keto, or fasting? Have you heard of something called the keto flu? Here's the thing. The keto flu is not actually a condition. Nope. Keto flu just refers to a bundle of symptoms. Headaches, fatigue, muscle cramps, and insomnia that people experience in the early stages of keto dieting. Here's what's going on.  

When you eat a low-carb diet, your insulin levels drop. Low insulin, in turn, lowers the production of the hormone, aldosterone. Now, aldosterone is made in the kidneys and it helps you retain sodium. Low aldosterone on a keto diet makes you lose sodium at a rapid rate. Even if you are consciously consuming electrolytes, you might not be getting enough. In particular, you need electrolytes, especially sodium and potassium, in order for nerve impulses to properly fire. 

Robb Wolf, who as you guys know is my hero in the holistic health world, worked with the guys at Ketogains to get the exact formulation for electrolyte supplements to formulate LMNT Recharge so you can maintain ketosis and feel your best. LMNT Recharge has no sugar, no coloring, no artificial ingredients, no junk. They're used by three Navy SEALs teams. They are the official hydration partner to Team USA Weightlifting, they're used by multiple NFL teams, and so much more.  

Guess what? We worked out an exclusive deal for The Intermittent Fasting Podcast listeners only. Guys, this is huge. They weren't going to do a deal. I begged them, here we are. You can get a free LMNT sample pack. We're not talking discount, we're talking free. Completely free. You only pay $5 for shipping. If you don't love it, they will even refund you the $5 for shipping. I'm not kidding. The sample pack includes eight packets of LMNT, two Citrus, two Raspberry, two Orange, and two Raw Unflavored. The Raw Unflavored ones are the ones that are safe for your clean fast, and the other ones you can have in your eating window. Word on the street is the citrus flavor makes an amazing margarita by the way.  

I am loving LMNT and I think you guys will too. Again, this is completely free. You have nothing to lose. Just go to drinklmnt.com/if podcast. That's DRINKLMNT dotcom forward slash IF Podcast. And I'll put all this information in the show notes. All right, now back to the show.  

Shall we jump into everything for today? 

Gin Stephens: Yes. We have some feedback from Annie. And her subject line is “The Best NSV,” which stands for Non-Scale Victory for anyone who doesn't know that. All right, she says, “Dear Gin and Melanie. About a year ago, two different gynecologists told me that I had PCOS because I had various symptoms. They gave me different pills, but I always felt that there was so little information, and I started to read a lot about it on my own. When I searched for insulin on the podcast app, I found your podcast in January of 2020. I listened to your then around 200 episodes and started to fast. Sometimes only 16 hours, sometimes 40. I always did what felt best for my body at the moment. After some months, I stopped taking the pills since it didn't make me feel good. And since then, my period has been super regular. I haven't missed a month.  

After a while, I told my best friend who is a medical student that I was fasting, and he has now become more hooked than me, and we've been doing it together ever since. I feel that I'm so incredibly in tune with my body more than I ever was before. I feel better, and I've learned so much during this journey.  

I always thought that I wanted to email you with a thank you. And today, I got the best reason because I was just told by a gynecologist that I do not have PCOS anymore. Since I started, I have not lost any weight, but I don't really need to either. But this feels like the greatest success. All in all, I just wanted to tell you that you are amazing, and that I cannot thank you enough. Lots of love to you both, from Sweden.” And lots of love to you too, Annie, and that is amazing. PCOS is related to having high levels of insulin. It sounds like fasting has lowered your insulin enough to reverse your PCOS, which is incredible. 

Melanie Avalon: Yeah, that is so fantastic. Thank you so much, Annie, for sharing. PCOS is one of the conditions that is looked at a lot in the clinical literature with fasting. This is often found to be the case that it can be reversed. If you'd like to learn more about insulin, I did an interview with Dr. Benjamin Bikman and his book, Why We Get Sick, is so good for understanding insulin. And he talks about PCOS. He basically thinks that insulin is the cause of PCOS always. I also love that she's sharing it with her friend who's a medical student.  

Gin Stephens: I know, I love that.  

Melanie Avalon: Yeah, it’d be nice if fasting could infiltrate the conventional medical system. 

Gin Stephens: I think it's happening, really. I think that it is slowly but surely making its way. 

Melanie Avalon: Yeah, I think so too. All right. Shall we go on to our questions?  

Gin Stephens: Yes.  

Melanie Avalon: We have a question from Laura, the subject is “Question about increasing body fat percentage.” And Laura says, “Hello. Thank you, ladies, for all that you do to promote intermittent fasting and provide us all with excellent information. You have both been a great support to me, and I appreciate your resources and continued education on IF. My question is this. I've been doing IF for about five months, not for weight loss, but it started as a structured way to fast for Lent. I liked it so much I kept going with IF. I started at 127 pounds, plus/minus 2 pounds, I had the whoosh effect and lost five pounds and a dress size after two to three weeks. I am 5’2”, and I now stay around 122 pounds plus/minus 2 pounds. I love how I look, and as a mother of four busy kids, ages 2 years to 14, I have more energy and time.  

I fast for 18:6 most days with a 20:4 once a week. However, over the past month, although my weight is staying the same, my scale which also measures body fat percentage is trending upward. Each week, the body fat percentage increases around 0.3%, and the muscle mass is trending down at the same rate. Although I don't have my waist measurements, my honesty pants fit great. My diet has not changed. I eat clean and feel best with a high fat, low carb diet. My activity and sleep have not changed significantly. Any thoughts? Should I try to open my window more and add more protein, weight training? I'm also 40. Maybe this is age related, open to suggestions and ideas. Thanks again for all your efforts, Laura.” 

Gin Stephens: Well, Laura, thank you for writing in. What I know about those scales, the home versions, is that they tend to be inaccurate, and they do a lot of measuring water, and your body is fat. So, they're not good at really measuring because the way they work with bioimpedance, they're sending an electrical signal through your body, and it really can't distinguish between fat and water. So, if your honesty pants are still fitting exactly the same, that's a great sign. I don't know that's really what's happening with your scale. Also, try changing the batteries, I had something crazy happening with my scale one time, and I changed the batteries and it fixed it. I would not say, “Oh my gosh, I'm gaining fat and losing muscle.” That could be what happening is happening. I don't know. But I would not just go by the fact that your scale is saying that just because I'm not sure that's accurate. 

But if you really do feel like you're losing muscle, then you need to do muscle building activities, so weight training would be a great thing to do. I don't know that I would have a longer window, but you could certainly increase your protein if you'd like, see about that. Really, it's just hard to know if that's what's really happening. So, it's hard to say what to do. But if it is happening, then working on building muscle would be a great thing to do. What do you think, Melanie? 

Melanie Avalon: Yeah, you said pretty much the entirety of my thoughts. Those scales, I really wouldn't recommend. Especially the ones that you buy and have at home, they're so influenced by water. Even things how hydrated or dehydrated you are can massively affect it. If you did want to actually measure, I would instead do more of the old school measuring. There are formulas online you can do with taking actual measurements. Or if you go to a gym, they often can help you out more with that. 

But basically, I thought Gin really nailed it in that it might not be actually happening. If it is, either way, it's not going to hurt you to focus on muscle. Age related muscle loss is a thing. We tend to lose more muscle as we age. So, focusing on maintaining or even building it is fantastic, so weight training, resistance training. I'm going to have an episode pretty soon with John Jaquish, he makes the X3 Bar system, and I'm very much a fan of that system now. That's resistant bands, and his protocol, actually, it's so short. You do it a few days a week and it's like 10 minutes. It's made to maximize all of your muscle maintenance, muscle gains with minimum stress. I should remember this after doing the interview, but it works with the range of motion to give all of your muscle the maximum muscle building stimulus without being limited by range of motion.  

When that episode comes out, I'd recommend listening to it, but it's going to be a while. But in the meantime, his system is at melanieavalon.com/x3 and the coupon code, SAVE50, will get you $50 off. It's nice, because I don't think there's anything going on with your scale. I don't know that your scale is accurate, but it's nice that it tunes you into the importance of your muscle because it really can't hurt to focus on muscle. Adding in activities and also adding protein, definitely, I agree with Gin, I wouldn't lengthen the window necessarily, but adding more protein could be a nice thing.  

Gin Stephens: Awesome.  

Melanie Avalon: We are on the same page there.  

Gin Stephens: Very nice.  

Melanie Avalon: Shall we go on to our next question? 

Gin Stephens: Yes. We have a question from Becky and the subject is “Question about blood glucose.” She says, “Hi, Gin and Melanie. I have a question about blood glucose.” [laughs] Maybe I shouldn't have read that part, because I just said that, all right. She says, “I started wearing a CGM two weeks ago, just out of interest. I'm not diabetic or prediabetic. And my A1c and glucose levels are normal. However, occasionally throughout the couple of weeks, my blood glucose has dropped into the very low range. This is not during fasting, which I tend to do for 16 to 18 hours per day, but it's usually during my eating window. And I've been trying to pay attention to things and it doesn't necessarily happen after I eat sugary foods, but more often seems to be after I have carbs. Usually during fasting, my glucose levels are 4.8 to 5.3.” Now, is that Australian or European? I’ve no idea what 4.8 to 5.3 is. 

Melanie Avalon: Yeah, 3.3, for example is 60. 4.7 is 85. 5.5 is 100. Normally, her fasting glucose is between around 86-ish to upper 90s. Normally, it's hers in the 90s, and it's dropping to the 50s. 

Gin Stephens: To the 50s after she eats? 

Melanie Avalon: Mm-hmm.  

Gin Stephens: Okay. She says, “Do you know why this big drop happens and/or, if this is a problem? My thought is that my insulin response is too great and drops my blood sugar too low, and then it takes a bit of time for my glucagon to kick in and bring my sugars up again. What are your thoughts? Thank you, Becky.”  

Melanie Avalon: All right. This is a great question from Becky. The first thing I would suggest, Becky, is if you have access to it, I would get a glucometer. Something where you can check your blood sugar with on your finger, and I would check the meter to see if the baseline correlates because occasionally the CGM can be off by 10 points, maybe even more. I would just do that to check. If the baseline is off, it doesn't mean, and we talked about this before, but if the baseline is off, the precision will be correct. So basically, even if it's off by 10, it'll always be off by the same 10. Check that just so you can figure out because it's possible, I could see how it would be off, and maybe that drop isn't quite as low as you're thinking it is. In any case, regardless, the job is happening. The precision is accurate. And, yes, this actually is pretty common. I experienced this.  

I was wearing a CGM for months, then I took some months off. Now I'm wearing one again. I've been wearing one for about three weeks now. Right now, my blood sugar is 90. The pattern I've noticed in me is actually very similar to you, Becky. I have fasted blood sugar that's good throughout the day. Actually, when I do cryotherapy, it shoots way high up and then it goes down. After I eat, I get the same drop like you do. It doesn't go down to the 50s, but it does drop a lot and then it goes back up again. And I do think it is a basically a hypoglycemic response from over, I don't know, if I'm over producing insulin, but I mean, I guess so. And then finally, it raises again when your body makes the-- Is she doing a low carb diet? 

Gin Stephens: She didn't say. 

Melanie Avalon: She didn't say. If she was doing a low carb diet, then it would be probably things like glucagon or the liver producing cortisol to bring back up the blood. If you're eating a high carb diet, it could just be a matter of the carbs getting shuttled into the cells and then released back and then levels become stable again. So, is it a problem? Well, I'm not a doctor. I don't know how much of a problem it is. My question to you is, when this happens, do you feel starving and ravenous? Or would you not have had any idea this was happening if you hadn't worn a CGM? 

Gin Stephens: I wonder if she's shaky, because I feel if your blood glucose is dropping down and you feel shaky and unwell, that's a problem.  

Melanie Avalon: She says it doesn't necessarily happen after I eat sugary foods, but more often seems to be after I have carbs. Okay. 

Gin Stephens: If she's not feeling shaky, what's so interesting is the fact that we're wearing these CGMs now, people who had no idea what their blood glucose is doing are like, “Hey, this is what my blood glucose is doing. Is it normal?” When really, we wouldn't even have had any idea. So, maybe that is totally what Becky's has always done, and it's normal. 

Melanie Avalon: The thing, I think, is something to be more worried about, because if you're having these drops, but you're not experiencing them as a negative feeling in your body, I personally wouldn't be too concerned. I wouldn't be as concerned about the lows. It's more the super highs that people don't realize are happening. Those are what I think are pretty concerning. Either huge, massive spikes, so they don't realize are happening or baseline high resting blood sugar levels that they don't realize is happening. I wouldn't stress out too much about it. 

I would check the CGM. What you could do is you could play around though and this is one of the great benefits of having a CGM is you can figure out what really works for you. So, there's no harm in playing around with your food choices and your macros, and seeing if you can find a type of diet or meal or combination where you don't experience that crazy low. Thoughts, Gin? 

Gin Stephens: That was it. Also, if you're really concerned, you really do need to check with your doctor just to make sure. We don't know what's really normal for you or what's happening. Feeling good is always a good sign. And it's just interesting that we wouldn't even know what was happening if we didn't have these devices now.  

Melanie Avalon: They're fascinating. I'll put a link in the show notes to the two episodes that I've done on CGMs. One is with Levels and one is with NutriSense. Then, if you'd like your own, the links for those are melanieavalon.com/levels, lets you skip their waitlist. They say their waitlist is 115,000. And then, melanieavalon.com/nutrisensecgm gets you $40 off with the coupon code, MELANIEAVALON, so you can jump on the CGM train for anybody interested. I heard back from ZOE, and I think I am going to do the muffins. They send a CGM, right?  

Gin Stephens: Yes.  

Melanie Avalon: Oh, does it link to their practice, the app? 

Gin Stephens: Yes. You don't see what your numbers are doing. It's the old school. It's not like Levels. It automatically sends it. Unless it's a new one.  

Melanie Avalon: Oh, you don't scan anything?  

Gin Stephens: No.  

Melanie Avalon: Oh, so you don't even see the numbers. That's interesting.  

Gin Stephens: You don't see the numbers, you just see your wave. Now I was able to see my numbers because I synced it. Maybe it's different now, but it was the old-style FreeStyle Libre, where you actually have a readout. It's like a little device.  

Melanie Avalon: Oh, not on your phone, not on your app. Oh, interesting. 

Gin Stephens: It might be different now, because technology changes. I have the Levels at my house to do, I'm going to wait till I get home from the beach, do it in September. They sent it to me to try. Thank you for having them do that. I'm really excited to try it, but it's really different. Since I'd done the ZOE, I feel like I'm missing, what is this? But you just attach it to yourself, but that's it, and then you scan that. So, it's different than that. 

Melanie Avalon: I'll let you know if it changed. 

Gin Stephens: It might have changed, but I was able to sync, you had to then get your little sensor reader and it would sync with the sensor reader. And then I was able to take the sensor reader and connect it to my computer, and then upload it through this third-party system and see what my numbers actually were. 

Melanie Avalon: You know what made me so excited recently in this whole sphere?  

Gin Stephens: What? 

Melanie Avalon: Did you know they make HbA1c meters?  

Gin Stephens: Nope.  

Melanie Avalon: I was concerned because I got back my HbA1c and it was two points higher than it's been, and that did not make sense to me. And I was lamenting to my friend, James Clement, who I've had on my show. He wrote a book called The Switch. And he was like, “I'll send you a meter.” It was like a glucometer, but it tests your HbA1c. It was so exciting. Except the lancet to get the blood for it was very intense. It requires more blood and I was not anticipating the lancet being so effective.  

Gin Stephens: Good luck with the ZOE test because you do have to squeeze out a lot of blood for that one. You have to drip it on this card, lots of it. That was the worst part. I did not like dripping my blood and squeezing, squeezing, squeezing to get all the blood out because it has to go up. Like on a pregnancy test, it has to go up, the liquid, you have to get enough blood that it goes up this little like-- 

Melanie Avalon: They send the lancet, right?  

Gin Stephens: Yeah, they send you all that.  

Melanie Avalon: If it's like the lancet that came with HbA1c meter, I was fine, because it was very effective.  

Gin Stephens: Well, I didn't like it. I didn't like doing that part, but I did it. It was worth it for the data.  

Melanie Avalon: Worst-case scenario, I guess I could go in any lab test now, do a blood draw. Yep.  

Gin Stephens: Awesome.  

Melanie Avalon: All right. Okay, so our next question.  

Gin Stephens: All right, we have a question from Rebecca, and the subject is “Fasting Insulin Number,” which should fit in very nicely, because it talks about some things we just said. “Gin and Melanie, before I jump into my long email, sorry, thank you for making a difference in my life and countless others. I wrote a question last year and you read it in Episode 194. Thank you. It was in regards to my HbA1c.” 

Melanie Avalon: Oh. Look here. Oh, wait, I just realized we didn't even say what HbA1c is. I'll say what it is after. 

Gin Stephens: Okay. She goes on to say, “You mentioned about getting a fasting insulin test done, which I did via a walk-in lab this past May. Here's an observation and a question since in Episode 221, you both talked about glucose and fasting insulin possibly going hand in hand. Well, after fasting 12 hours, my glucose was 116, but my fasted insulin was 2.5. I can't swing a CGM, so I just have to rely on periodic blood work. Any thoughts on these very far apart numbers? I am 60 years old, 5’10” and 149.03, and an athletic build. My CRP, which indicates inflammation, a diabetes indicator as well, is 0.50, which is great. You two have become best friends in my head, and thank you and so sorry for this very long email. Obviously, I am not good at condensing.”  

Melanie Avalon: All right, Rebecca. Well, thank you so much for your question. Well, first of all, bravo for being interested in all of this, and testing your fasting insulin on your own. That's so cool that she decided to do this. Both blood sugar and insulin, the tests can fluctuate a lot. I think that's one of the things with a CGM that people really realize is just how much blood sugar can fluctuate throughout the day, which can be pretty misleading for people getting blood tests, because there are so many factors that could affect your blood test. When you go into the doctor, you could get a blood sugar spike for something unrelated to your overall blood sugar levels, and it can make it seem like your blood sugar is either lower or higher than it normally would be. Insulin as well, we don't know quite as much about the stats on insulin but I did ask Dr. Bikman this, personally, not from this question, but from another question, wanting to know about fluctuations in insulin. He was saying that, yes, the tests could fluctuate, and they could also be off the same way that blood sugar can be. 

I say all that to say it could have been misleading information. It would be nice-- I know, she said that she can't swing doing it a lot. It would be nice if you could do it again and see if you have that same pattern, because if you continue to have that pattern, that would be a little bit strange, but this is just my thoughts, I'm not a doctor. This was a fasted test, so 12 hours. The fact that the insulin was so low, I feel like that's a more stable reflection of how the insulin is while you're fasting, because it's unlikely that if you were that fasted, that you're fasting insulin would just spike up, compared to blood sugar, which you could have gotten nervous or had some coffee or exercise, or the liver just decided to pump out some more glucose, that can easily spike up. It's really nice that you had that low insulin number. What I'm saying is, it's very possible that you have low insulin and that you also normally have lower blood sugar, but it just spiked, but again, it's hard to know. 

What I would do, is I know you aren't able to get a CGM right now, you could get, we mentioned earlier, a glucometer. Those are pretty affordable. And the great thing is they let you check your blood sugar all the time. It's like unlimited blood sugar tests, you just have to buy the test strip refills. Compared to the earlier things we were talking about large amounts of blood needed, tghere are tiny, tiny pricks that are required. I have a Keto-Mojo and it actually measures both ketones and blood sugar. I also have a Bayer blood sugar. I'll put links in the show notes to both of those. What I would recommend is if you really want to figure out what was going on, since you can't get the CGM right now, get a glucometer if you're open to it and start testing your blood sugar throughout the day just to get a sense, and then next time you check your insulin, see if it is again low.  

What's really interesting is, I was just learning about the HOMA score. There's actually a calculation that you can do, and I want to go back and look at my lab test and do and you could do it for this. But it's a mathematical equation to determine insulin resistance based on your glucose and insulin. Although now having said all that context about how the numbers can be off, I do wonder about the implications of it if the numbers are off a little bit. It's the HOMA-IR formula. And it's actually fasting glucose times fasting insulin divided by 405, and you want that to be less than 2 for insulin resistance, ideally, like the lower the better. Rebecca, your HOMA-IR score is actually 0.71, which is really great. I don't know, I would not be too concerned, if you like I would do any of the things I said about continuing to monitor, but those are my thoughts.  

And then, the HbA1c, because we didn't define it. It is a marker of blood sugar levels over three or four months, and that's because the turnover of the red blood cells is about that length. So, it shows overall level of glycation of your blood cells from blood sugar in your bloodstream. I always forget the numbers. You know what’s really interesting, Gin, I find this fascinating, and it I find it concerning. Did you know that-- I don't know when it was, I was just reading a book, they raised the level of HbA1c for diabetes, like an entire point? 

Gin Stephens: No, I didn't know that. 

Melanie Avalon: I just find it concerning that, we adjust our standards to a disease population, why? We have the standard population, but because of the rise of diabetes and metabolic issues, I just don't know that it's helpful to raise the standard. 

Gin Stephens: Well, it's like I was talking to somebody yesterday recording the podcast, Intermittent Fasting Stories, and she was talking about her fasted insulin levels. She just got her number, and she said that she was told by her doctor that the range from, I can't remember something under 5, I can't remember the number that he said to 20 was normal. I'm like, “Well, 20 might be normal, but it's not healthy.”  

Melanie Avalon: For insulin?  

Gin Stephens: Yeah. But that's what I'm saying is-- and the same with the A1c, like you were just talking about, they've raised it to be normal, and that's not normal.  

Melanie Avalon: Yeah, it's very concerning. That's why we love-- on here, we've worked with InsideTracker before, and what they do is they do blood tests, but they look at it by their ideal ranges, rather than the conventional ranges, which I think is so, so important. 

Gin Stephens: There's so much difference between 20 and 5, for example, with insulin. If you got an insulin of 19, that ain't good. it might be normal, but certainly not optimal. 

Melanie Avalon: Yeah, I don't have it right now but I think the A1c had an increase from like 5.5 to 6.5 for diabetes. 

Gin Stephens: I wonder what the reasoning is, is that they want to diagnose fewer people officially? What would be the motivation for doing that? Insurance companies doing it for some reason? 

Melanie Avalon: Yeah. Because the reason you could say is, “Oh, well, more people have higher levels, so that's what's normal, so that's the standard.” But to change the definition of diabetes, I don't know. It's a good question. 

Gin Stephens: Yeah, I would like to know why.  

Melanie Avalon: That would be interesting.  

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Melanie Avalon: We have a question from Dana. The subject is “Meal timing during eating window.” And Dana says, “I currently do a 17:7 daily fasting.” Whenever people say that one, I always pause because I feel like it's -- like most people don't say 17:7. 

Gin Stephens: [laughs] I don't know why, people just like even numbers? Well, what's funny is people do 19:5. People do 19:5 or all the other. So, I don't know why 17:7 wouldn't be a thing. If you could do 18:6 or 16:8, you could certainly do 17:7, or you could even do like 16.5:7.5. [laughs]  

Melanie Avalon: Oh, goodness. Well, Dana is doing 17:7. She says, “I could easily do with just lunch, 12 to 1 PM, and dinner at 6 PM. But I am worried about getting enough protein and fiber and just two meals, so I have a chia seed fiber/protein shake that I tried to get in, in addition to lunch and dinner. What is the best timing to have that snack? Midpoint between lunch and dinner, or is it better to cluster it with either lunch or dinner to maximize the number of hours between meals and the eating window?”  

Gin Stephens: Now, Dana, I would like to have you define the word 'better' for yourself. There's so many things, like which is better for convenience. What happens in the middle of the afternoon if you have it then? Does it make you hungry after you eat it because I know that if I have just something small random, in the middle of-- let's say I was going to eat two meals one day, and then lunch, and then dinner, and then I had something small in the middle, it would make me hungry or sooner. You just have to fit that in where it feels right to you. I'm not going to claim any of them is better. So, if it works better to have it with your lunch or with your dinner, do that. If you like having it in the middle of the afternoon, have it then. If it makes you feel weird after you have it, then don't have it then. But if you have it in the middle of the afternoon, and you look forward to it, and you love it and you feel great after you have it, have it at that time.  

Melanie Avalon: Yeah, I agree. With me and my digestive issues, I would do for me, for example, what would feel the best digestively. I know she's asking about maximizing the hours between meals. 

Gin Stephens: I try not to worry about all that, because once your window's open, your window is open, your body's digesting food, there's stuff going on. I just figure window's open, window's closed. I don't want you to really micromanage the window so much and worried about what's the best thing. I don't know, that's just my brain thinking. I know some people think differently than me and that's all right, too. 

Melanie Avalon: To that point, exactly, depending on what you're eating, but it's highly unlikely in my opinion that you'd be able to eat at 12, and again at 6 and enter the fasted state in between. So, you're not going to be entering the state of turning on the epigenetic changes and the signaling pathways for the fasted benefits. So, there's really no point in trying to achieve that goal. You can just keep eating in between, but the thing is, that doesn't mean that, “Oh, I'm in the eating window, so it doesn't even matter if I just keep eating.” What I mean by that to clarify is just because you're not going to hit the fasted state, doesn't mean that eating more isn't eating more. 

Gin Stephens: That's meaning we're not recommending overeating. I could make a case for that it's “better" to have it in the middle, just after going through ZOE, and realizing it takes your body a while to clear out, the excess glucose, the excess fat and then having too much in your body at one time. Marty Kendall even talks about this. Too much energy in your body at one time, so you want to spread it out a little bit. Having in the middle of the afternoon, I don't think is a bad thing.  

Melanie Avalon: Yeah. I like your answer. Definitely a question where just do what feels right. I think people really-- [sighs] so much of this is self-experimentation and just finding a window that works for you. And that sounds like a cop-out answer, but there's not some perfect solution and some perfect answer that you're magically going to find. I think we will stress a lot about doing everything right, if that makes sense. 

Gin Stephens: Yes. Well, there's got to be the best time to have this. There's so many things going on in your body. Like I said, when I went through the ZOE testing and understood, when I spaced my food, too close together, I got a lower score, because my body hadn't had time to clear out the last one. Also, the volume makes a difference. I've had a little bit and then later I had a little bit, that's different than having a whole lot, then having more. The way that you crowded them together can be a problem if you're having too much.  

Melanie Avalon: Yeah. I think it's so freeing with fasting and diet as well. I think it's really freeing to-- okay, this is my analogy. I have an analogy, Gin. I feel it's like a coloring book with the outlines. When you're a kid, and you pick up a coloring book, and you're trying to decide which one to color, you find the picture with the outline that you like, and then you just really stick to that outline, and then you color it in however way that you want. With the fasting, you can pick a window that you're sticking to, and then just trust the process, trust the outlines, and color within that.  

Gin Stephens: And you can color it however you want. Yes, that makes me think of when I was five, I entered--- I don’t know I guess my parents entered it for me, I don't know, but I won this coloring contest. And I looked back-- and my mother kept this, this picture of a Christmas coloring contest. I looked back at it years later, and I had colored Santa crazy. It was like the Santa, he didn't have on a red suit when I was done. It was crazy. Of course, this was like, what 1974? So, maybe they really appreciate it. Maybe I was the only five-year-old who entered, I don't really know. But I certainly did not color it in the standard way. 

Melanie Avalon: You know what so funny? Did we talk about this? We're the same person. It's just funny how we have the same stories about-- When I was also around five, I did a coloring contest, but I had just learned-- what was that TV show with a guy and he teaches you how to color that Bob or something.  

Gin Stephens: You mean the painting guy? 

Melanie Avalon: Yeah.  

Gin Stephens: On PBS? 

Melanie Avalon: Yeah.  

Gin Stephens: Yeah, I don't know. I forgot the name of it, but yeah. 

Melanie Avalon: I learned the technique of how to do progressive shading. It was like this gymnastic coloring piece and I worked so hard to perfectly shade it so that it gave the depth to the-- what is it called? What do you--  

Gin Stephens: Did you say you were about five?  

Melanie Avalon: Yeah.  

Gin Stephens: See, I didn't do it like that. I just went crazy and colored it all crazy.  

Melanie Avalon: We did the same thing, but we're opposites.  

Gin Stephens: The opposite of it. Yeah. My picture was crazy. But it was like, “Color, color.” I mean, Santa had green, it was just-- yeah. [laughs] I was not following the rules.  

Melanie Avalon: I was implementing the technique. Oh, my goodness. That's so funny. I won so much stuff, I got to go see like gymnast, like the collegiate gymnast, and they gave me all this swag.  

Gin Stephens: Well, I won a tricycle and I was already too old for a tricycle, so I remember being mad. I was like, “I am not a baby. I do not need a tricycle. Thank you.” [laughs] Anyway. 

Melanie Avalon: Back to the analogy though, the point I'm trying to make was that, once you pick that outline, the outline is the fasting window in my analogy. 

Gin Stephens: You can color Santa green, or you can do a technique. It's okay. 

Melanie Avalon: But then on top of that, you might not like how you colored it. Just because there's a boundary doesn't mean that it's going to work for you. You can still color it however you want, and you can color it a way that you like or you can color it away that you don't like, but I think there's a freedom in having that boundary of the fasting window and just trusting that process.  

Gin Stephens: Exactly.  

Melanie Avalon: Alrighty, in any case, this has been absolutely wonderful. A few things for listeners before we go. If you'd like to submit your own questions for this show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. There is all of the stuff that we like at ifpodcast.com/stuffwelike. The show notes for today's episode will have a complete transcript and they will have links to everything that we talked about. That will be ifpodcast.com/episode230 and then you can follow us on Instagram. I am @melanieavalon, Gin is @ginstephens, and we are @ifpodcast 

Gin Stephens: Awesome.  

Melanie Avalon: All right. Anything from you, Gin, before we go? 

Gin Stephens: No, I think that's it.  

Melanie Avalon: All right. Well, this has been wonderful and I will talk to you next week.  

Gin Stephens: All right, talk to you then. Bye.  

Melanie Avalon: Bye. Thank you so much for listening to The Intermittent Fasting Podcast. Please remember that everything discussed on the show is not medical advice, we're not doctors. You can also check out our other podcasts, Intermittent Fasting Stories, and the Melanie Avalon Biohacking Podcast. Theme music was composed by Leland Cox. See you next week. 

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Gin: GinStephens.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Mar 14

Episode 204: Dental Health, Disappearing Cavities, Stomach Size, Fasting Insulin, Thyroid Tests, And More!

Intermittent Fasting

Welcome to Episode 204 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Gin Stephens, author of Delay, Don't Deny: Living An Intermittent Fasting Lifestyle

Today's episode of The Intermittent Fasting Podcast is brought to you by:

 BUTCHERBOX: Grass-Fed Beef, Organic Chicken, Heritage Pork, Wild-Caught Seafood: Nutrient-Rich, Raised Sustainably The Way Nature Intended, And Shipped Straight To Your Door! For A Limited Time Go To Butcherbox.com/ifpodcast And Get Free Ground Beef For LIFE!!

BLUBlox: Overexposure to blue light in our modern environments can lead to increased anxiety, stress, headaches, and other health conditions. Even a tiny exposure to artificial light can completely offset your circadian rhythm! Unlike many “blue light blocking” glasses on the market, BLUBlox provides glasses that block the exact blue wavelengths you need to regulate sleep, reduce anxiety, and much more! They also provide different types of glasses for the time of day, season, and your personal electronic and light exposure! Plus, for every BLUblox purchase, they donate a pair of glasses to someone in need! Go To blublox.com And Use The Code ifpodcast For 15% Off!

JOOVV: Like intermittent fasting, red light therapy can benefit the body on so many levels! It literally works on the mitochondrial level to help your cells generate more energy! Red light can help you burn fat (including targeted fat burning and stubborn fat!), contour your body, reduce fine lines and wrinkles, produce collagen for epic skin, support muscle recovery, reduce joint pain and inflammation, combat fatigue, help you sleep better, improve mood, and so much more!! These devices are literally LIFE CHANGING!! For A Limited Time Go To joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get Free Ground Beef For LIFE!!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter, And Something Magical Might Happen After Your First Order!

Fast This Way: Burn Fat, Heal Inflammation, and Eat Like the High-Performing Human You Were Meant to Be (Dave Asprey)

The Melanie Avalon Biohacking Podcast Episode #84 - Dave Asprey

Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon

Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

BLUBLOX: Go To blublox.com And Use The Code ifpodcast For 15% Off!

Listener Feedback: Kay - Intermittent Fasting Saved my Teeth

Gin's Waterpik WP-662 Water Flosser Electric Dental Countertop Professional Oral Irrigator For Teeth, Aquarius, Black

Melanie's Dr. Collins Perio Toothbrush

Listener Q&A: Marisa - Small Portions

Does Dieting Actually Make Your Stomach Shrink?

Listener Q&A: Nita - Hopefully not too late (but may be) for 200th Episode of the IF Podcast

JOOVV: For A Limited Time Go To joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

Listener Q&A: Paige - Any suggestions for M.D. lab work

Episode 52: The THYROID Episode, With Elle Russ!

The Melanie Avalon Podcast Episode #12- Elle Russ

LETSGETCHECKED: Get 30% Off At Home Tests For Thyroid, Vitamin D, COVID, And More, With The Code IFPodcast30 At trylgc.com/ifpodcast!

INSIDETRACKER: Go To melanieavalon.com/getinsidetracker And Use The Coupon Code MELANIE30 For 30% Off All Tests Sitewide!

Listener Q&A: Ron - Women Only?

Life Lessons, with Gin & Sheri Podcast

TRANSCRIPT


Melanie Avalon: Welcome to Episode 204 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my co-host, Gin Stephens, author of Delay, Don't Deny: Living an Intermittent Fasting Lifestyle. For more on us, check out ifpodcast.com, melanieavalon.com, and ginstephens.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment. So, pour yourself a cup of black coffee, a mug of tea or even a glass of wine, if it's that time, and get ready for The Intermittent Fasting Podcast.

Hi friends. I'm about to tell you how you can get free grass-fed, grass-finished ground beef for life. Yes, for life. We are huge fans of a company called ButcherBox. They make it easy to get high quality humanely raised meat that you can trust. What they do is they deliver 100% grass-fed, grass-finished beef free-range organic chicken, heritage-breed pork, and wild-caught seafood shipped directly to your door, by cutting out the middleman which is the grocery store and working directly with farmers, they are supporting huge changes in the future and sustainability of our health and the environment. The value is incredible. The average cost is less than $6 per meal. That is delicious, 100% grass-fed, grass-finished beef where the cattle are free to roam on pasture. Their hogs are also raised on pasture or in hoop barns. Their bacon by the way is sugar and nitrate free. How hard is that to find? Their chickens are humanely raised with outdoor access with no cages, crates, or crowding, and they uphold the strictest of standards when it comes to fishing practices. They have an array of options, four curated box options as well as their popular custom box, so you can get exactly what you and your family love. If you want to learn all of the details, check out the very extensive blog post I did when researching, that's at melanieavalon.com/butcherbox.

And here is that amazing offer we have for you guys for a limited time. New members can actually get two pounds of grass-fed, grass-finished ground beef for free in every ButcherBox order for the rest of your life. I am not making this up. Just go to butcherbox.com/ifpodcast, to get free grass-fed, grass-finished ground beef for life. That’s butcherbox.com/ifpodcast and I'll put all this information in the show notes.

Are you concerned about aging? Well, thankfully, fasting is super incredible for its anti-aging benefits. It activates genes in your body called sirtuins, which repair your body and help extend lifespan. Also, during the fast, your body can clean up a lot of harmful chemicals which may be taxing your detoxification systems. In fact, the reason people go gray is because their detox systems start producing a lot of hydrogen peroxide when dealing with toxins. Do you know where a lot of those chemicals come from? Your skincare and makeup. As it turns out, there are thousands of compounds found in conventional skincare and makeup that Europe has banned due to their toxic nature and the US has banned less than 10. When you put these on your skin every single day through your skincare makeup, you're adding to your body's burden and likely aging your skin faster.

Thankfully, you can easily clean up your skincare with a company called Beautycounter. They make incredible products that are extensively tested to be safe for your skin. You can feel good about every single ingredient that you put on. They also have an amazing anti-aging line called Countertime. Friends, this is a game changer. It's full of active ingredients which nourish and support your skin, reduce fine lines and wrinkles, and support a beautiful glow. It also has a safe alternative to retinol, so you can get all of the anti-aging benefits of retinol without any of the toxic effects of retinol, because, yes, that stuff is toxic. Guys, put it away now.

You can shop with us at melanieavalon.com/beautycounter. If you use that link, something really special and magical might happen after you place your first order. Also, definitely get on my clean beauty email list that's at melanieavalon.com/cleanbeauty. I give away so many free things on that list. So, definitely check it out.

Lastly, if you anticipate making safe skincare a part of your future, just like Gin and I do, definitely become a band of Beauty member. It's sort of like the Amazon Prime for safe skincare. You get 10% back on all of your purchases, free shipping on qualifying orders, and a welcome gift that costs way more than the price of the membership. It's completely worth it. Friends, are you fasting clean inside and out? You can with Beautycounter. Again, that link is melanieavalon.com/beautycounter. And we'll put all this information in the show notes. All right, now back to the show.

Hi, everybody and welcome. This is Episode number 204 after Intermittent Fasting podcast. I'm Melanie Avalon and I'm here with Gin Stephens.

Gin Stephens: Hi, everybody.

Melanie Avalon: Happy Valentine’s Day, Gin.

Gin Stephens: Oh, yeah, we're recording on Valentine's Day, even though people are not going to hear it for a month, [laughs] but I hope everyone had a great Valentine's Day. It's cold and rainy here.

Melanie Avalon: Yes, it is. How is everything with you?

Gin Stephens: Well, I am coming to you from my new computer and I'm so excited. Melanie knows a little bit of this saga, but listeners, y’all do not. [laughs]

Melanie Avalon: Does it feel wonderful?

Gin Stephens: Yes. Let me let me tell you a little backstory. About a year ago, I decided that my laptop wasn't cutting it and I needed a dedicated desktop computer for recording podcast to put in my podcast studio, so I didn't have to go look for my laptop, drag it around that sort of thing. So, I got a new Mac, and I got the wrong one. I made a really bad choice. I didn't realize how much RAM I needed. I'm a big Apple fan, love Apple products, been in the Apple ecosystem. Since the very first iPhone came out, I had one within months. I've been iPhone all the way, Apple computers, love them. But I got one with not enough RAM. My son Cal, who's an app developer said, “What? I can't even believe they sold you that.” I'm like, “Thank you, Cal.” I didn't know. Melanie and I, again, for the audience, Melanie knows this whole story. Melanie said to me, “Oh, you just change out, add more RAM.” Well, I bought one where you could not do that. You could not add your own RAM. I was like, “All right, I have to get a new one.” In there, the big ones. I can't go to the Apple Store, everything's closed due to the pandemic. I had to order over the phone. The guy was like, “Yeah, you get this one here. You add the RAM. It's so easy.” Melanie did that.

Melanie Avalon: Gin was like, “It's going to be hard.” I was like, “No, it's so easy.”

Gin Stephens: It's so easy. Yeah, it was so easy. The RAM came, just like Melanie said, there's a little thing, the computer got here. Of course, it took a month because the pandemic everything shipping slowly. I opened a little window in the back where you just plug in the RAM, I got the RAM that Apple guy told me to get. I plugged in, the computer would not start up. It kept shutting down, an endless loop start up, not start up, start up, not start up. Then I put the old RAM back in that it came with, still wouldn't start up. I don't know if I got a dud computer. I don't know if it was dud RAM, but then my old RAM wouldn't work either. At one point, I was laying on the floor trying to get to the little window [laughs] it was just almost comical. Apple is fantastic, though. They took it all back, helped me find the one I really needed. I was like, “I don't care if it costs more, I'm getting the right one that comes with all the RAM to start with.” The girl on the phone was fantastic, the Apple support person.

She's like, “Alright. This is the amount of RAM that will be enough for you.” I'm like, “Great. Give me double that because I do not want to go through this ever again.” It's here. I'm on it. The screen is bigger. Oh my gosh, it's so fast. Melanie, I could not even open two things at one time before, and now I can have everything. The mail’s open, the calendar’s open, Chrome is open, Safari is open, Word is open, I don't know if I sound excited, it's because I am.

Melanie Avalon: No, it's so exciting. I remember when I got my new computer, and it's like, “Oh, I can do things.” Especially when the nature of our business is using our computer-- I mean lots of people are using computers, but I'm using it every day for work and it's just so freeing when you can just do things.

Gin Stephens: It really, really is. I feel if only I hadn't bought that other one a year ago, but then I felt like I was committed to it. I'm like, “I just bought this computer a year ago,” and it was not cheap. Fortunately, I sound like an Apple commercial, but I did the trade-in program, so yeah, I was able to get a good bit back from the trade in program. Someone who does not need a lot of RAM is going to be really happy. I can't believe that it was not as easy. It would have been fabulous, but no.

Melanie Avalon: Exciting. I'm glad we match now. Yours is similar to mine.

Gin Stephens: It's the 27-inch, which I also thought was going to be too big, because the little desk I use-- well, I use an old Baker's rack. It sounds crazy. I sit on a stool, it's a very narrow Baker's rack that I've used for my desk. Chad was like, “That computer is way too big. It's not going to work.” Well, it does work. It works perfectly. I have a bigger screen, so I can see my document. It's just fabulous. It's not too big at all.

Melanie Avalon: I'm excited. I've been waiting for this moment.

Gin Stephens: Well, I have too but I was being very stubborn. You know when you make a bad purchase and you're angry that you made a mistake, but you just spent a lot of money? My anger was what if I make another bad mistake and buy the wrong thing again, which actually happened, but thank goodness Apple was amazing about it.

Melanie Avalon: Or, it's like, is it the sunk cost fallacy? Where you've put in so much energy and effort into something that you don't try something new because you've already committed so much? It's not the same thing.

Gin Stephens: It is, I know exactly what you mean and that was exactly true. It was finally when Chad said to me, and Chad likes to save money. Okay, so let me put it that way. If you could pull your two-ply toilet paper into two single pliers, and then he would do that. Not really, but you get my point. He was like, “You just get a new one.” I'm like, “Oh, okay,” not that I need his permission. I do not, but when he was like, “Get a new one.” I'm like, it finally felt like, “You're right. I should just get a new one,” so I did.

Melanie Avalon: Yes, you should.

Gin Stephens: I also have another thing to share that is interesting. You know how I had talked about how I've been opening my window with my main meal, and feeling so great?

Melanie Avalon: Yes. Are you not anymore?

Gin Stephens: No. I realized it messed up my sleep.

Melanie Avalon: Oh.

Gin Stephens: This is so interesting. My sleep got worse and worse over time, and then I finally connected that to opening my window earlier. Here's what the problem was with my sleep. Actually, my sleep wasn't worse, but it shifted it, and let me explain.

Melanie Avalon: Wait, I just want to guess.

Gin Stephens: Okay, guess how it shifted my sleep.

Melanie Avalon: You changed to eating more food earlier, right?

Gin Stephens: Like at 2 o’clock, I was having my main meal at 2 o’clock instead of 6:30.

Melanie Avalon: I would think it would shift your sleep earlier, but I'm guessing since you're not liking the effect that maybe it was the opposite?

Gin Stephens: It shifted it so much earlier that it was ridiculous. I wanted to go to bed at 8 PM every single night. I was like, “It's 8 PM, I've got to go to bed now, I am so tired.” Then, I was waking up. I've gotten my clock set to not show a light till 5:30 in the morning. I was waking up, probably around 3 o’clock ready to get up, like wide awake, like I was going I wanted to go to bed so much earlier and I wanted to wake up so much earlier. I was fully rested. It's like it shifted my-- what's the word I'm looking for?

Melanie Avalon: Your circadian rhythm?

Gin Stephens: Well, yeah, it's like it changed my circadian rhythm, like shifted it earlier. I was like, “Well, this doesn't work for me at all.” Unless I wanted to get up at 3 AM every day bright and bushy tailed and go to bed at 7 PM. So, an early window does not work for me, boom, now I know it. If I had to get up at 4 AM, this would be 100% the right thing to do.

Melanie Avalon: That's probably really valuable. You're already pretty familiar with different eating windows and how they affect people, but I bet it was a valuable experience for making suggestions to people.

Gin Stephens: And it also helps me see that doesn't mean that, that this is what everybody should do. But for me, it really impacted what my body wants to do. My body prefers to eat later for the main meal and then go to sleep at some point after 9 PM and then wake up by about 5:30. That's what feels good to me. My body likes to wake up early, but by eating my main meal earlier, it shifted everything, my whole rhythm just changed and got out of whack.

Melanie Avalon: That's one of the things I really love about intermittent fasting, is if there's some reason where my sleep the night before and then my wakeup schedule on a given day is off, I can really always reset it in one night and I think most of that has to do with I just eat my dinner at the same time as I would have regardless, and that just always just sets it right back.

Gin Stephens: It's also one of those things that makes me so frustrated every time I see a one-size-fits-all recommendation, like early eating windows are better.

Melanie Avalon: Yeah, exactly.

Gin Stephens: Or, we should all have our main meal at 2. I could take what works for me and say everyone should have their main meal for dinner, but no, that's not true. Anyway, we're all different and that just keeps being proven over and over again. I have friends, their main meal is breakfast time. They eat early in the day, and then they're done for the day and they feel better.

Melanie Avalon: I wish I was like that.

Gin Stephens: Well, I don't wish it.

Melanie Avalon: I know we've talked about this. We've had this conversation.

Gin Stephens: Right. In but in fact, one of my guests that I just interviewed, it was fascinating for Intermittent Fasting Stories. She said that she doesn't get the great energy during the day while she's fasted. She has great energy after she eats. She has an early in the day window with great energy all day. So, I’m the opposite. That's why everyone has to really find what works for them. I mean, just over and over, that is just shown. Anyway, I'm just so tired of so many people thinking that here's what you have to do, and everyone should do, and this is what is right for all.

Melanie Avalon: I just finished reading Dave Asprey’s new book, Fast This Way, because I'm interviewing him on Friday, which is very surreal. Very surreal. Do you know what he said was the reason we started eating breakfast?

Gin Stephens: I can't remember I skimmed all through his book, I got a copy of it, and skimmed through the whole thing really fast. Because I'm doing a million things, I didn't have time to like sit with it. But no, I can't remember what he said.

Melanie Avalon: He said it was because of train schedules. When we started using trains, and they were train schedules. I had not heard this before.

Gin Stephens: I don't know if that's true. [laughs] Sorry, Dave Asprey.

Melanie Avalon: I made a note, I was like, “Look that up.”

Gin Stephens: I actually have heard other--

Melanie Avalon: Maybe it would have been one of the things.

Gin Stephens: Maybe, I've heard breakfast wasn't a thing until certain points in history when people then suddenly started eating breakfast. It was really only like rich women would get up and have a little breakfast, but nobody else would.

Melanie Avalon: I think he talks about some of the other things, but he said, like, the thing was the train schedules. I don't know.

Gin Stephens: Well, if I had a train schedule, I still wouldn't eat before I got on the train. I don't know how that would make me have breakfast anyway. I don't know, but I don't remember reading that because like I said, I skimmed it.

Melanie Avalon: Yeah, I'm pretty excited. I am going to ask him a lot of questions about bulletproof coffee. It's going to be a fun time. Listeners will have to listen to it when it comes out. Can I do two quick plugs?

Gin Stephens: Sure. No, no, you cannot. Kidding.

Melanie Avalon: One plug is, and this goes back to the Valentine's Day, this will have been over by the time this comes out, but definitely follow me on Instagram, friends, because if you had been following me right now, I am giving away two Apollo Neuros on my Instagram, which is just crazy.

Gin Stephens: Very cool.

Melanie Avalon: Those are the Soundwave therapy devices that instantly stop stress with the touch of a button and I use mine all the time. The second plug, I plugged this a few times before already, but if you're interested at all in clean beauty and safe skincare, join my new Clean Beauty and Safe Skincare Facebook group. It's really taking off. I'm really enjoying it.

Gin Stephens: If you'd like to follow me on Instagram, you can see pictures of my cats and my flowers and my beans. [laughs] Oh, good times. I actually put cats yesterday, but did you see that one? Ellie was so cute all wrapped up in the little blanket, did you see that one?

Melanie Avalon: I just pulled it up right now.

Gin Stephens: Oh my God, she's so sweet. [laughs] Yes, my best friend might be a cat. I don't know. Is that weird?

Melanie Avalon: No. I love cats.

Gin Stephens: She follows me all around the house and whatever I'm doing.

Melanie Avalon: That's something we have in common. We're both cat people.

Gin Stephens: Yay. See, there's so many things.

Melanie Avalon: There's like two things. I'm trying to think what else. There was something else recently we realized, but for new listeners, Gin and I were pretty much opposite on almost everything.

Gin Stephens: On many things.

Melanie Avalon: From preference stuff, so like food-- maybe just food. Just food. Oh, and cold and sleeping. It's like body things.

Gin Stephens: Well, circadian rhythm things.

Melanie Avalon: Food. Yeah.

Gin Stephens: The temperature our shower is going to be. [laughs]

Melanie Avalon: The clothes we wear, again, body things.

Gin Stephens: Exactly.

Melanie Avalon: Friends, I have a story for you. I recently got septoplasty to fix my deviated septum so that I could breathe better. And in the recovery period, you're not supposed to wear glasses. Oh, my goodness. I cannot tell you how much I realized how much I adore and need and love BLUblox blue light blocking glasses. I've been wearing them every single night of my life until I got that surgery. Guys, you need this in your life.

In today's world, we're way overexposed to blue light. While blue light is energizing, we're not supposed to be seeing it 24/7. It can raise cortisol, stress levels, create tension and headaches, disrupt your sleep, and so much more. Of course, there are a lot of “blue light blocking glasses” on the market these days. Andy Mant, the founder of BLUblox, he personally realized how incredible blue light blocking glasses were for him personally. So, then he did something crazy and actually tested all the brands on the market to see if they actually were blocking blue light like they said they were. They weren't really. That's why he took things into his own hands to create glasses that would block the blue light you need to be blocking to truly have the healthiest relationship possible with light. That's also why he made BLUblox light blocking glasses in a lot of different versions.

They have clear computer glasses you can wear all day while looking at the computer. They have their SummerGlo lens that blocked the draining form of blue light while still allowing in some of the energizing wavelengths. They're also tinted with a special yellow color, scientifically shown to boost mood. And of course, they have their Sleep+ lens, you can put those on a bed and it's just like, bam, tired. At least that's the way it works for me because actually blue light can block melatonin production, which helps us naturally fall asleep.

Also, get their Sleep REMedy Mask. Oh, my goodness, I use it every single night. It gives you complete blackout while still putting no pressure on your eyes, like you wear it, and you can open your eyes completely, and it's completely black. It's mind-blowing. In case you're wondering, I'm still not supposed to be wearing glasses, but I ordered this weird contraption head thing to hold the glasses over my eyes because I just really need the blue light blocking glasses in my life. These glasses also come in a huge array of styles, so you don't have to feel like a weirdo biohacker like me. You can really get any style or frame to fit your personal style. You can shop with us at blublox.com, that's B-L-U-B-L-O-X dotcom and use the code, IFPODCAST, to get 15% off. Something else amazing, for every pair of glasses you buy, BLUblox donates a pair of glasses to someone in need. The glasses can also come in prescription, made to order. Again, that's blublox.com with the coupon code, IFPODCAST, for 15% off. All right, now back to the show.

Shall we jump into everything for today?

Gin Stephens: Yes.

Melanie Avalon: To start things off, we have some listener feedback, and this comes from Kay and the subject is “Intermittent Fasting Saved My Teeth.” Kay says, “Hi Gin and Melanie. Not a question but thought you could share this story with your listeners to highlight one of the many hidden benefits of IF. I started IF about 18 months ago. At that time, I had a dentist appointment where I found my first cavity at age 30 with four other spots on my teeth that were on their way to becoming cavities. One of those four could have been filled at the time, but the dentist said it could wait, so I chose to wait because I was nervous about my first filling. The dentist said at my next visit, we would likely book fillings for the other four. I was so devastated. I brush, floss, and rinse twice a day and always prided myself in never having a cavity my entire life. While today I had my yearly checkup and expected to leave with plans to fill these four cavities, they are gone.

At my last appointment, the dentist said three to four could be reversed, but likely that wouldn't happen because I already brushed and flossed twice a day, they're all gone. I told him I had started intermittent fasting, and he said that without a doubt that reverse the tooth decay process. By not eating often throughout the day, food and plaque isn't building up on my teeth and contributing to the cavities. He also said that fasting can reverse gum disease because the food isn't in your mouth giving bacteria a home. I started for weight loss and, in the process, saved my mouth. Just wanted to share. Thank you for introducing me to this lifestyle.”

Gin Stephens: Love it.

Melanie Avalon: Anybody in your Facebook groups talked about this before?

Gin Stephens: Well, I think it's remarkable that the cavities are gone. I don't know if I've ever heard that. Like her body just remineralized her teeth and filled that all in? That's astonishing. You can't argue that it happened. I actually interviewed Melissa Wages for Intermittent Fasting Stories, Episode 12. She's a pediatric dentist, and so she talks about all the ways that intermittent fasting is beneficial for our dental hygiene. If anybody's looking for that, search for Intermittent Fasting Stories, go to Episode 12, listen to Melissa Wages, pediatric dentist and intermittent faster, but yeah, remarkable.

Melanie Avalon: I think it's really interesting because a lot of doctors say that the mineralization of the teeth is something you can never reverse. I feel like I see a lot of people, not necessarily in intermittent fasting communities, but people just in holistic food and holistic health communities who say quite the opposite.

Gin Stephens: Yeah, I've seen that too.

Melanie Avalon: Even actually, when I interviewed James Nestor, who wrote the book, Breath, he made some change. I think it was breathing related or chewing related, it was one of those. He grew, I think, he said like a dime-sized worth of new bone in his jaw. Basically, you can grow new teeth or bone. Very motivating.

Gin Stephens: Yeah, it's been a while since I've been to the dentist, so I recently started going to the dentist a couple years ago again. I had to get some crowns, which were no fun. Dental health is important. Have you ever used a Waterpik?

Melanie Avalon: No. Every time I think about it, I just remember my roommate in college got one because they were becoming pretty popular.

Gin Stephens: They were really popular in the 70s and 80s. I can remember being a kid and everybody had a Waterpik and I was like, “That looks so fancy.” I never had one.

Melanie Avalon: Did you get one?

Gin Stephens: I just got one. My dentist recommended at my last visit.

Melanie Avalon: What does it do? Does it squirt water really?

Gin Stephens: Yes. Crowns are new to me. I had not ever had crowns, and so now I have a couple crowns but food was getting all trapped in there and I was like, “Oh, my God, this is disgusting.” She's just like, “Get a Waterpik. Get a Waterpik.” I'm like, “Okay.” So, I did.

Melanie Avalon: I'm glad we're having this conversation because my roommate in college got it. She got it and then she said that it wasn't working in our teeth were getting worse and I had written them off is not something to get, so hearing you say this--

Gin Stephens: Oh, my dentist it suggested it. It's like amazing. I brushed my teeth first and then I use the Waterpik and let's just say it's pretty amazing what the Waterpik gets out of there.

Melanie Avalon: Do you still floss at all?

Gin Stephens: Well, it depends on who you ask. My dentist said it does not take the place of flossing but let me just tell you that maybe at my house, it does. So, don't tell her. [laughs]

Melanie Avalon: I want to order one.

Gin Stephens: I really like it. Yeah, I got one on Amazon. She told me which one to get. Let me tell you get the one with a reservoir, instead of the handheld reservoir. You want one that plugs into the wall and as a big reservoir. Do not put just cold water in it. Let me tell you, it needs to be warm-ish.

Melanie Avalon: Okay.

Gin Stephens: Like a bunch of cold water on your teeth and gums does not feel great. It is too cold.

Melanie Avalon: We can put a link in the show notes for listeners, which will be at ifpodcast.com/Episode204 to the one that Gin got. I'm going to order it too.

Gin Stephens: Okay, awesome. We’ll see if you like it. I really, really do. It surprised me. She also made me get one of those electric toothbrushes to brush--

Melanie Avalon: The sonic ones.

Gin Stephens: Yes. I hated it, hated it. I don't like it. Don't like it. I cannot use it.

Melanie Avalon: They scare me so bad. They remind me of tooth sensitivity.

Gin Stephens: Well, I didn't like it. Apparently, I brush too hard and so she's like, “You’ve got to get this one. It's like so much better for your teeth.” I can't do it. I tried and then I hated it. Then I went back and they're like, “You're not using it.” I'm like, “Okay,” and then I tried again. I'm like, “No, I just can't.” I just don't like them. It makes my whole head feel weird.

Melanie Avalon: They just remind me of dental cleanings, I think.

Gin Stephens: I don't know, it made my head vibrate in a weird way. She's like, “Is something wrong with you?” I'm like, “I don't know, maybe.” [laughs] I love my dentist. She's hilarious.

Melanie Avalon: I have to share my favorite toothbrushes. I will put a link to them in the show notes. Especially if you brush really hard, they're the Perio ones. You can get them on Amazon. They're so soft. If you brush really hard, it's really good for not scraping away your teeth.

Gin Stephens: Well, I didn't know I brush too hard, but she told me I do. I think I also use the electric one too hard probably, I don't know. Also, here's a fun fact about me. If I try to write with a pencil, it snaps the point every time. I just apparently apply a lot of pressure to whatever I do.

Melanie Avalon: That's funny.

Gin Stephens: I know. I can't write with pencils, I can't brush my teeth, I need help. [laughs]

Melanie Avalon: Whenever somebody pulls out a pencil, I'm like, “Wow.” I feel people don't use pencils much anymore.

Gin Stephens: Well, I do use pencils sometimes. Really, I have to use the regular kind. I can't use whatever one’s, automatic pencils, what are they called-- mechanical pencils. I can't use mechanical pencils because the lead is too small. I really can't write with mechanical pencils, but I can use a regular pencil.

Melanie Avalon: See, another example. I can't write with normal pencils. I have to use mechanical pencils.

Gin Stephens: Yeah, I love normal pencils. Yeah, fun fact, we can split a pack of pencils, get all the regular, you get all the mechanical. We'll be good to go. All right, yep, great dental hygiene. Just another benefit of intermittent fasting. We do hear it all the time, people come back and have their best checkups ever. Thank you so much for sharing.

Melanie Avalon: I have one more fun fact that's related. I'm reading right now, the newest-- I don't think it's a rewrite, but you know the GAPS diet?

Gin Stephens: I am familiar with it. I can't remember what it stands for.

Melanie Avalon: Her first one's stands for gut and psychology syndrome. It's about healing the gut primarily for mental health issues, but all different issues. Her newest one is GAPS, it's gut and physiology syndrome. It's talking about other issues as well. It is blowing my mind.

Gin Stephens: Just basically the connection between the gut and our mental health and our whole body, is that the point?

Melanie Avalon: Yes. The GAPS protocol is a very specific protocol that a lot of people follow to try to restore gut health. In the beginning, it's a lot of gut-healing nutrients, and you'd slowly introduce fermented foods, and it has only well-cooked veggies in the beginning and meat and all this stuff. I'm reading the newest version of her book, and it's very long. Oh my goodness, it is the most in-depth thing I have read yet about the gut microbiome.

Gin Stephens: Well, that's good to know.

Melanie Avalon: She goes through bacteria, archaea, fungi, protozoa. This blew my mind. Did you know that there's this form of bacteria called the L-form bacteria? Basically, a lot of bacteria, they can just change what they are. They can be one bacteria one day and then there another bacteria the next.

Gin Stephens: I did not know that.

Melanie Avalon: Yeah. Or, they can do it with our body cells. They can become our own body cells. She said it's a huge problem in studying bacteria because it's like we think we've been studying bacteria in isolated forms, but really they could become other things. Then, also she says that antibiotics-- because when they become the L-form-- sorry, this is such a tangent. When they become the L-form, they lose their cell wall and then they can, I guess, change to something else. She said what antibiotics do is they tend to destroy the cell walls of bacteria. We haven't been taken into account that it doesn't necessarily destroy the bacteria, that they can in a way shape shift to something else. Really, really fascinating.

Gin Stephens: It's so interesting.

Melanie Avalon: Oh, and the reasons related was, she said that the oral microbiome in the placenta, and that the child experiences in the beginning actually most closely resembles our oral microbiome.

Gin Stephens: That's interesting.

Melanie Avalon: Women with less-than-ideal oral microbiomes, it actually has a big effect on their children. It's crazy.

Gin Stephens: It is so interesting. We're learning so much more all the time. When I was talking to Tim Spector’s people after I went through the Zoe test, I was like, “Gosh, this is so much different than the information I got back in 2017,” which doesn't feel like very long ago because really there was like three years difference between I had a test in 2017 with the American Gut Project, and then again in 2020, through the Zoe app, three years. But they're like, “Oh, yeah, three years ago, we didn't know anything, compared to what we know now.” This is really so cutting edge, like you read something that was written about the guT3 years ago, we know so much more now that's different. It changes. Because they couldn't sequence what was down there. They really just started to have a look in there.

Melanie Avalon: Yeah, exactly. We barely look in the small intestine.

Gin Stephens: The more I learn though, the more I'm like, “Alright, there's so much we don't know, let's just don't even worry about it, just eat good food, do intermittent fasting, move on.”

Melanie Avalon: I don't know. I think a holistic, broad approach through diet is probably most beneficial. I have not read too far into the book, but she says basically, that the largest part of our bacteria is in our gut obviously, and that the biggest change we can make to that is through our diet and that will affect the bacteria throughout the rest of our body as well.

Gin Stephens: Right. It's all connected, everything is connected.

Melanie Avalon: We're just little worlds hosting all of these other symbiotic lifeforms that are living with us.

Gin Stephens: Your health is directly related to the health of that community.

Melanie Avalon: 100%. That's basically her thesis.

Gin Stephens: You can't be fully healthy if your gut’s not healthy.

Melanie Avalon: She even goes so far as to say if you have a really healthy, robust gut microbiome, that you won't get IBS, like you won't get these things. She thinks that it's a required factor of having a messed-up gut microbiome for a lot of diseases and illnesses that we experience.

Gin Stephens: I think so. I really, really do think so. This is the next frontier and we had it all the time, which we didn't know, it's always with us.

Melanie Avalon: Right in our own backyard.

Gin Stephens: Literally. [laughs] On that note, let's go to our first question from Marissa. The subject is “Small Portions.” She says, “Hello, ladies. I've been listening to the podcast for a while now and have been fasting for a little over a year with great results. You’re both super helpful with all the knowledge you share. Here's my question. My mom insists that when I open my window, I need to eat a small portion of food whenever I eat. Now, she's saying that if you eat smaller portions, your stomach shrinks, which to me doesn't make sense. Perhaps, she's living the diet lifestyle. Maybe you guys would know what I should explain to her to help her understand.” All right, so what do you say to Marissa and most importantly, Marissa’s mom?

Melanie Avalon: All right, Marissa, thank you so much for your question. This is definitely a prevailing myth out there that our stomach significantly shrinks, that it permanently becomes smaller or larger based on the size of food that we're eating. I did a lot of research on it and that's just not the case. When we eat a larger volume of food, yes, our stomach does expand substantially. Our normal stomach, if it has no food in it, it can contain about 200 milliliters of volume. How big is that, 200 milliliters?

Gin Stephens: Well, I'm picturing a graduated cylinder in my head that was 100 milliliters, so it's bigger than you think.

Melanie Avalon: 200 milliliters is about seven ounces?

Gin Stephens: Right.

Melanie Avalon: Okay, so that's when there's no food in our stomach. When we eat more, when we eat a large volume, it expands accordingly and it can expand a lot. So, yes and no. The problem isn't really from the stretching, or the thing that might possibly be a factor in there, but I don't think it's something to be too concerned about. Stretching, so eating a large volume of food is most likely not going to be a problem, that’s what the stomach is accustomed to do. If you're eating more, it doesn't necessarily make you want to eat more to feel full. There's so many different factors going into satiety, and the stomach literally stretching is only one of them. A lot of it has to do with hormones released, based on what you're eating, there's just a lot of factors. For eating less, there has been a study in mice and they did find that when they reduce the mice’s intake by 20% for over four weeks, it did reduce a few of the important factors in the stomach wall that affect how much food the stomach can accommodate. It's possible that if you're eating smaller amounts, you'll slowly need less to feel full. I don't think it's so much the opposite, where if you're eating a lot that you're going to be eating need to eat a lot. Even for example, in professional overeaters, which you cannot pay me to be a professional overeater, but that doesn't really affect their normal stomach.

They've also found that obese patients or obese people don't really have any different stomach size than normal people. Basically, there's a lot of factors involved in satiety, you don't really have to worry about the large volume being a problem. It is possible that if you're eating really small meals all the time, that maybe you might get fuller sooner. But I don't think it's that much of a concern. Your thoughts, Gin?

Gin Stephens: This reminds me of a very funny diet that came out in the late 80s. I can't remember the name of it. I was watching TV, it was in the morning, you were watching The Today Show or something. It was like my friends from college where because we're in college at the time. I remember sitting in, we were in my dorm room, and the guy was like, “On this diet, you just eat according to the size of your fist. You can eat whatever you want, as long as it's the size of your fist, because you don't want to stretch out your stomach.” We're like, “That's so dumb.” What if I ate a piece of butter the size of my fist? What if I ate-- [laughs] we were only in college, but we already thought that sounded dumb. That was the whole diet plan. Size of your fist, that's how much you get to eat. [laughs]

Melanie Avalon: I'll put a link in the show notes. I found a really good article in Smithsonian that talks all about it. They even said-- because they're the ones where they talk about that mice study, but they even said even with those findings, I'll even quote it, they say, “It is also highly unlikely that short-term fasting is enough to produce long-term changes in the stomach. Based on our data from animals, we don't have any evidence that a day is enough to do this.” So, yeah.

Gin Stephens: Even then, I could see that eating the amount of food, the size of my fist was not going to be a good long-term dietary strategy. That one never really did take off, but someone sure was trying to sell that on The Today Show. I think they had a diet book, but it was not one that people remember.

Melanie Avalon: Yeah, I don't remember that one.

Gin Stephens: Probably, they just went on The Today Show, and everybody's like, “No, that's dumb,” and then no one did it.

Melanie Avalon: Yeah. Oh, one other thought. It also talks in this article about patients who have anorexia, if they haven't been eating at all, that might be the type of long term, not getting enough, where they might not be able to actually accommodate more food. But that actually reminds me of something else from the GAPS book, she talked about how people are actually starving, the gut bacteria can accommodate to where they extract more calories from food, which is really interesting. Specifically, the archaea, they're not bacteria. In anorexic patients, they usually have high levels of archaea, and it might be like a protective mechanism because it's extracting more calories from food. Very interesting.

Gin Stephens: That is interesting. Of course, knowing what we know about the relationship between the gut and our psychological health, I have a chicken or the egg question about that. Is it the anorexia causing the gut to be different or the gut difference is causing the anorexia?

Melanie Avalon: Yeah, I've thought about that as well. It's really interesting. All right, shall we go on to our next question?

Gin Stephens: Yes.

Melanie Avalon: All right. This is some lingering leftovers from when we asked for Ask Me Anything for Episode 200, and I just think these are fun and they keep rolling in. This is from Nita, and the subject was, “Hopefully not too late, but maybe for the 200th Episode of IF Podcast.” Sort of too late, but not really because we're answering it. Nita says, “Hi, Melanie and Gin. I'm probably too late to add a question for your episode. You may have already recorded it, but I thought I do a ‘Would you rather’ game for you both.” Okay, so here's her game. “Would you rather give up IF forever or be forced to eat all the foods you dislike during the eating window?”

Gin Stephens: Well, I am not going to eat any foods I dislike ever. Ever. I'm not going to do it. I only eat foods I like. But again, I also can't give up IF forever because I'm sleeping, so even if I'm only fasting from over night--

Melanie Avalon: Gin, you're not allowed to do-- this is the would you rather game.

Gin Stephens: I'm sorry. I'm one of those loophole people. If the genie said you have one wish, I would wish for all the wishes. I'm sorry I'm looking for that loophole, but I don't know how to answer it. I have a hard time answering it, because--

Melanie Avalon: I feel you would do fasting, give up IF forever, because you would get your fasting during sleeping.

Gin Stephens: Yeah, I just have decided I'm never going to eat foods I don't like, ever.

Melanie Avalon: Okay, so that answers that question.

Gin Stephens: I guess. I really also am not giving up I have forever. I'm the worst. I'm sorry.

Melanie Avalon: Gin is the worst to play would you rather with.

Gin Stephens: I don't like this game. I'm like, “No, I'm not doing either of those.” I reject the having to pick one.

Melanie Avalon: I would rather give up IF forever.

Gin Stephens: Yeah, I knew you would say that.

Melanie Avalon: It's similar to what you just said, I'm just not going to be in a place where I put in foods I don't want to put into my body.

Gin Stephens: Well, I guess, I would accidentally be fasting because I would not eat them. No matter what I'm fasting.

Melanie Avalon: Second question.

Gin Stephens: This one's easy. Thank goodness, I can answer this one. Go ahead.

Melanie Avalon: Oh, good. I was like, I don't know. Okay. Would you rather give up doing a podcast or give up writing books?

Gin Stephens: Well, I'm writing a new book right now, and as I've mentioned in earlier episodes, I'm like, “Why? Why am I writing this book?” I would give that up. Sorry, if anyone's listening, it's going to be a really good book. I go through periods of struggle with it, but it's going to be a really good book, but the writing process is very, very hard. It is more mentally draining than anything I've ever done in my life. Would you agree with that, Melanie?

Melanie Avalon: I would agree with that statement.

Gin Stephens: Whereas doing podcasts is fun.

Melanie Avalon: Exactly.

Gin Stephens: It's so fun. I would do 27 podcasts. [laughs] I love writing books, so don't get me wrong. I'm a writer. I'm really, really proud of the one I'm working on now. I think it's going to be good. I think it's going to be helpful. I just wrote about you in it, Melanie. I said Melanie was right about something.

Melanie Avalon: Really?

Gin Stephens: Yeah. You'll have to wait to see what that is. I'll tell you off the air, and I didn't want you to be right.

Melanie Avalon: Oh, I'm excited.

Gin Stephens: I put my finger in my ears, la, la, la, but you were right about something. The more you look at the evidence, the more you're like, “Okay, she's right.” [laughs]

Melanie Avalon: I do want to thank you, Gin, for putting up with all of my-- I'm always like, “Gin, this--” I don't know, I'm always saying my thoughts about things.

Gin Stephens: Well, that's what we do. But it's so much fun doing a podcast. Doing a podcast, it is work, don't get me wrong. It's so much fun work. Writing a book is so much fun, like childbirth. [laughs] You're so happy that you have your children, but you're like, “Oh Lordy, this childbirth was really not that fun.”

Melanie Avalon: Probably finding out you have the book deal is like finding out you're pregnant.

Gin Stephens: Yeah, exactly. Then you're like going through the glow and then you have morning sickness, and then you're vomiting, then the baby has to actually come out. Your epidural doesn't take and then you're feeling every pain, and anyway. Then, you push for five hours. That's more than anyone needed to know. On the other end of it, you have this beautiful baby. And not everyone's going to like your baby, that's also true. The first time the school calls and they're mad about your baby.

Melanie Avalon: People still ask me if I'm married or have children. I feel it's blatantly obvious how much I'm not married or have children. I just want to clarify that at this moment.

Gin Stephens: I am loving having adult children. It's so wonderful having adult children.

Melanie Avalon: I think I could skip to that point.

Gin Stephens: They're like really good friends that you created. It's true. Anybody with teenagers or struggling along the way, it does get better.

Melanie Avalon: Do you know Tom Bilyeu?

Gin Stephens: I know the name. What does he do?

Melanie Avalon: He has Impact Theory podcast. He was the founder of-- I don't think he was the founder of Quest Nutrition, he might have been.

Gin Stephens: I've heard his name. I don't know much about him.

Melanie Avalon: He has a really cool show that's really similar in format to my show, the Melanie Avalon Biohacking Podcast. I think it's called Impact Theory. I feel he is me, but a man. He went to USC film school, then he wanted to do all of this health stuff and he wanted to produce a lot of health content in order to ultimately fund creative projects, which is basically my-- I don't know, we're very similar. In any case, he's married. He was on Mikhaila Peterson's podcast, who is well known in the carnivore movement, but she asked him about having or not having kids, because she has a kid and he said that I guess he and his wife decide not to have kids right now, but he knows. I guess they would regret having kids right now because of all they're doing with their business and their career and all that, but he said he knows hands down on his deathbed, he will regret not having kids, and so that's just a choice that he makes, like regretting it now-- or not that it's regretting it but choosing the downsides to not having kids now or later. That got really deep really quick, but it's something that resonates.

Gin Stephens: One of my sisters-- I only have one sister. One of my son’s siblings, my sister, [laughs] I have two brothers and a sister. My sister, she decided not to have kids and her husband, they decided together before they even got married, that they would just not have kids. She wanted to have the aunt relationship with kids, but not be responsible for kids. She's not regretted her decision for a minute.

Melanie Avalon: I think everybody just has to find what works for them.

Gin Stephens: Absolutely. All that from me saying that writing a book was childbirth. I was like, “How do we get to that discussion?”

Melanie Avalon: That's how this show goes down.

Gin Stephens: There you go. Yeah, writing books is hard. podcasts are fun, and also hard.

Melanie Avalon: All of it, though, is very gratifying.

Gin Stephens: It really is. It's fun putting stuff out into the world.

Melanie Avalon: Yes, I just love creating content.

Gin Stephens: I do too. I really do.

Melanie Avalon: Especially when it's content that has such a effect on people, like as far as the information that we share.

Melanie Avalon: Right. Is helping people to live their best lives and solve the problems that they're struggling with, and that's the name of the game.

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Gin Stephens: All right. We have a question from Paige, and the subject is, “Any suggestions for lab work?” She says, “I will be seeing my doctor on February 10th,” unfortunately, we have now passed this, Paige, but hopefully it'll help someone else. She says, “What are the suggested labs for someone 49 and female that has struggled to lose weight her entire life? I have done intermittent fasting but never done it clean. I usually drink things loaded with artificial sweeteners or heavy whipping cream in my coffee. This week, I decided I have to be going wrong somewhere. So, I'm going clean during the fasting hours and eliminating all artificial sweeteners. I'm a regular group fitness exerciser for 30 years and have always had exercise discipline. I'm 5’5 and weigh around 170, I do not have documented thyroid issues. I'm an RN. I plan on asking for a fasted insulin level, but please let me know if you have other suggestions. Thank you so much.” Can I just jump in and say something real quick, Melanie? I don't think you need to do any specific “Why am I not losing weight lab work?” Because you haven't been fast and clean.

Melanie Avalon: I knew you're going to say that.

Gin Stephens: Yeah. You've been spiking that insulin all along with an eating heavy whipping cream is food for the body. You have not done intermittent fasting the way we recommend get. Instead of asking what's wrong with my body, we know it's the cream, it's the sweeteners You need to treat day one as the day you went to the clean fast. If a year from now, you haven't lost any weight-- obviously, maybe don't wait a year, but that's when it's going to be time to start digging in. Not now.

Melanie Avalon: For those who have a fast and clean and they want to do lab tests--

Gin Stephens: That's a totally different question. Yeah.

Melanie Avalon: What lab tests do you think are most telling for why somebody might not be losing weight?

Gin Stephens: Well, she said the fasted insulin level, which I think is key. I think that every doctor should do a fasted insulin level even before an A1x, and I've talked about this before, we've discussed it on this show. If your insulin level is really, really high, your fasted insulin level, it's hard for you to lose weight. We've had people in the group that have struggled and they got a fasted insulin level and they're like, “Well, no wonder I've been struggling. My fasting insulin level is 20.” So, you’ve got to work on getting that down.

Melanie Avalon: Yeah, I would probably say there's a few different categories of things that could be indicators insulin, like Gin said would be great. She said she doesn't have documented thyroid issues, but that would be probably the second thing I would look at. You want to make sure that it's the full thyroid panel. If Paige has only tested-- because conventional doctors typically only test T4 and TSH. TSH isn't even a thyroid hormone, it's a pituitary hormone that signals to the thyroid. It just indicates what the pituitary is telling your thyroid to do, it doesn't tell you anything about what the thyroid-- I mean it's correlated to that, but it does not necessarily indicate what the thyroid is actually doing. T4 is the storage form of thyroid hormone. Again, it's a storage form, so it doesn't indicate the active levels in your body. I think it's crazy that the two things we test to evaluate the thyroid, none of it is the actual active thyroid hormone. Isn't that a little bit strange?

Gin Stephens: We test the things that are easy to test, right?

Melanie Avalon: I don't know if it's any easier to test those. The other ones if you're getting a full panel would be T3, so that's the actual active thyroid hormone, and then reverse T3. We've had Elle Russ on.

Gin Stephens: We have.

Melanie Avalon: Yeah, we've had Elle Russ on the show. I've had Elle Russ on my other show. I'll put links to it in the show notes. She was on the Melanie Avalon Biohacking Podcast. She has a really, really great book about hypothyroidism. I often share stuff about the thyroid with listeners, and I can't tell you how many times people tell me they go to their doctor and ask for a full panel, and the doctor will say that it just doesn't matter. Specifically, reverse T3, they say that it doesn't matter at all. But friends, reverse T3 is a thyroid hormone that can be made from T4. So, the storage form of thyroid hormone T4 can become either T3 or reverse T3. If it becomes reverse T3, it blocks the cells from taking in T3. You could have normal thyroid hormone levels like normal T3, but if your reverse T3 is high, it could be blocking all of that. So many people find the reverse T3 is high. That happens really because stress is the main factor. The body is perceiving a stress and so it is trying to slow down the metabolism because T3, the active form of the thyroid hormone is basically our metabolic piece of information hormone. It's what's telling cells to burn energy, to do everything they need to do. So, reverse T3 is a way to slow all of that down. You can also get tested for your TPO antibodies, and those will indicate if you have Hashimoto’s, which is the autoimmune form of hypothyroidism, which is the most common form. Some people even think that almost all thyroid issues are technically Hashimoto’s even if you test negative for the antibodies. That was a really long way of saying a full thyroid panel can be very, very helpful.

We've partnered before with LetsGetChecked. If your doctor won't do a panel for you. They have a thyroid panel, it doesn't have reverse T3 on it right now. It has T4, TPO antibodies, TSH, T3, and we have a discount code for listeners. I think if you go to trylgc.com/ifpodcast and use coupon code, IFPODCAST, that'll get you 30% off. Something you could do if you want to order it yourself is order that because it's really cost effective with our coupon. Then order reverse T3 ala carte off of another website or go into a place like Any Lab Test Now or something like that and they can probably do an ala carte reverse T3-- I'm still answering this question, so the thyroid.

The third thing I would say would be a full hormonal panel, and that's actually not usually a blood draw. It's something like a urine test. The DUTCH test is a really good hormonal panel you can do and that will show you all of your hormones, all of your cortisol, like your female hormones, so progesterone, estrogen. It'll give you a really good picture of you and what your hormones are doing. It's really hard to interpret. Admittedly, female hormones are not my expertise, I really don't know much about them, but that's something where you really want to work with a really functional practitioner who can interpret it for you.

A fourth thing you can maybe check would be CRP and any other inflammatory blood markers because those will show if your inflammation is really high in your body. If your inflammation is really high, that could be causing a lot of things and so you'd really want to find the cause of that. That could often be stress. It can really often be a food that's not working for you. It might indicate checking out your diet.

Then, I'll just real quick plug. Last thing, we also work with a company called InsideTracker, and if you want to order lab tests that they have ascertained through rigorous research, what blood tests actually correlate the most to health, longevity, and it's not really the tests that you're getting from your doctor. I mean it's some of them, but then it's some others that you're probably not getting. It's also different ranges than conventional doctors typically use. So, it can give you a really, really valuable picture of your “inner age,” which is what your age actually is based on your blood markers. I think we also have a 30% off code for them at insidetracker.com/ifpodcast, I'll put all of it in the show notes.

Gin Stephens: Yeah. That's a really good, thorough answer to the question. When people say, “Oh, my thyroid’s fine,” the moral of the story is, “Well, is it?”

Melanie Avalon: 100%. All right, so we have time for one more question. This is from Ron, this question was for Gin. The subject is “Women only.” Ron says, “Great book.” He's referring to Fast. Feast. Repeat. He says, “I truly enjoyed it. I did notice all of your testimonials were for women. Is there any difference in the IF [unintelligible [00:56:13] between men and women?”

Gin Stephens: Well, they're really not all from women. If you dig in, they're not even-- I'm not sure if he was talking about Fast. Feast. Repeat. or Delay, Don’t Deny.

Melanie Avalon: Oh, okay.

Gin Stephens: He didn't say, but neither of them are 100% from women. There are men in the back of Delay, Don't Deny. Not very many, but there are. There are men in Fast. Feast. Repeat. as well, not as many. I think the reflection of why it is a majority women reflects the composition of the Facebook groups. We just so happen that 90 something percent of the members of the Facebook groups are women. It's the skewed community, not that there's something different you need to be doing men versus women. No, not a single thing you need to do differently because you're a man.

Melanie Avalon: Yeah, my only caveat to that-- it's not really any different what you would do, but I do think women are more likely to experience potentially issues, not from the fasting per se, but because with fasting, they have begun over-restricting with everything. Female’s bodies are so much more sensitive to stress, as far as how it affects our reproduction and our menstrual cycles, and so it can affect our hormones if we get in that stressed-out state. So, it's no different at the beginning what you're doing, but I think women probably need to pay more attention that they're not over-restricting in their dietary choices, as well as the fasting to the point that it becomes too much of a stressor.

Gin Stephens: Yeah. I have a frequently asked question about that in Fast. Feast. Repeat. that over-restriction is not good for anybody, man or woman. But that is a trap that women tend to fall into because of the diet culture that's ingrained in us. Women-- just like that, what was her name, whose mom was telling her to eat tiny amounts of food? That's diet culture, and the whole idea of eat dainty amounts like a woman, well, you don't want to do intermittent fasting, and also eat dainty amounts of food like a woman because you're going to be overly restricting for your body. We don't recommend that for men or women. But women, I think, tend to be more likely to do it just because we're told not to eat a big meal in front of a date because it might-- I'm like, “Oh, forget it. I'm not doing that.” I can remember when Chad and I were dating, he's like, “Boy, you can eat a lot.” I'm like, “Thank you.” [laughs]

Melanie Avalon: I actually look forward to, if I am ever on a date, getting, like a really big steak or something just to be like, “See?”

Gin Stephens: I don't want to live a lie. I don't want to eat dainty in front of someone when I'm dating them. Then, when I really eat, I have to undo my pants buckle. No, I believed in being myself at all times.

Melanie Avalon: Me, too. That's another way we're the same.

Gin Stephens: Yay. We will be celebrating our 30th anniversary here in 2021. I still eat with gusto, as I did during the early days of dating.

Melanie Avalon: Is it this month?

Gin Stephens: No, it's not till July.

Melanie Avalon: Okay.

Gin Stephens: But it's coming, 30 years. I can't believe it, that's a long time.

Melanie Avalon: Three decades.

Gin Stephens: I know. It's like we grew up together. It feels like we were-- 30 years is more than half my life.

Melanie Avalon: Wow. Crazy. I was thinking like, how old would I have to be where I probably wouldn't reach the half my life thing if I got married.

Gin Stephens: Well, you're an intermittent faster, so you still have a lot of time.

Melanie Avalon: Yeah.

Gin Stephens: A biohacker and an intermittent faster, we're going to live a long time.

Melanie Avalon: If I do end up with somebody, I'm sure they're probably going to be a biohacker of sorts.

Gin Stephens: I can't imagine it any other way for you. No. [laughs] Cannot. “Honey, why is it red in here all the time?”

Melanie Avalon: I know. [laughs] There's so many things that you’d just have to be okay with.

Gin Stephens: Why are we sleeping in a Faraday cage? [laughs] What is this goat mattress? [laughs] Longtime listeners will get it.

Melanie Avalon: So many things.

Gin Stephens: Love it.

Melanie Avalon: All right. Well, this has been absolutely wonderful, so a few things for listeners before we go. If you'd like to submit your own questions to the podcast, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. You can get all of the stuff that we like at ifpodcast.com/stuffwelike. The show notes will be at ifpodcast.com/episode204. Like I said, you can follow us on Instagram, MelanieAvalon, GinStephens, and you can join our Facebook groups. Oh, yeah. Gin, do you want to plug your new Facebook group?

Gin Stephens: Our new podcast that I have with the cohost, Sheri Bullock, the Life Lessons podcast, and our community is called Life Lessons with Gin and Sheri. Oh, funny story, someone said the other day, they're like, “I love this group so much. It's my own private Google. This takes the place of Google.” Because anytime anyone has a question, they're getting real answers. You know how when you're trying to get like a product recommendation, and you're reading all the reviews, and some of them sound crazy and fake? Well, here we are just giving you real feedback. It's a lot more than obviously product reviews. We talk about everything. Seinfeld was the show about nothing. Well, Life Lessons community is the place for everything. People have talked about their divorces and their issues they're going through with their spouse and their family and “Which mandolin should I cut my vegetables?” Then someone's like, “Well, make sure you get the gloves.” I mean, we're really talking about everything.

Melanie Avalon: I love it. My group IF Biohackers is basically-- it's like Google for everything biohacking, and also mindset and diet, fitness, all of that.

Gin Stephens: For example, right before the holidays, someone's like, “My dad's in a memory care facility. Can anyone send him a Christmas card?” He got thousands of Christmas cards. It was like featured on their local news. It was amazing. If you like feel-good stories and positive things, join Life Lessons with Gin and Sheri, and listen to our podcast, we have our podcast.

Melanie Avalon: Podcasts that we would choose over books.

Gin Stephens: Oh, yeah, I know. I'm crazy with the podcast, three is a lot.

Melanie Avalon: Three is a lot.

Gin Stephens: It really is a lot.

Melanie Avalon: I've started actively, actively pitching my other show as a TV show, which would be really exciting.

Gin Stephens: That would be so exciting. That'd be so fun. That's your dream.

Melanie Avalon: Mm-hmm. It's going to happen. Manifest.

Gin Stephens: It's going to, we're putting it out there. I believe it.

Melanie Avalon: Yeah. If anybody who listens to this show, is in the TV creation/producing industry and has some advice they would like to share with me, I'd be happy to hear it.

Gin Stephens: Love it.

Melanie Avalon: If you do have any, email me at melanie@ifpodcast.com. All right. Anything from you, Gin, before we go?

Gin Stephens: Nope. That's all.

Melanie Avalon: Well, I will talk to you next week.

Gin Stephens: All right. Bye-bye.

Melanie Avalon: Bye.

Thank you so much for listening to the Intermittent Fasting podcast. Please remember that everything discussed on the show is not medical advice. We're not doctors. You can also check out our other podcasts, Intermittent Fasting Stories, and the Melanie Avalon Biohacking Podcast. Theme music was composed by Leland Cox. See you next week.

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Gin: GinStephens.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Dec 15

#452 – Intermittent Fasting For Type 2 Diabetes, Super Power Blood Tests, Biological Age, ADF Fasting, Special Occasions On Down Days, Cardio Vs. Strength Exercise During Fasting, TV Roles We Would Play, And More!

Intermittent Fasting

Welcome to Episode 452 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, biohacker, founder of AvalonX, and author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine, and Barry Conrad, actor, singer-songwriter, and creator and host of Banter with BC

SHOW NOTES


SPONSORS & DISCOUNTS


BIOPTIMIZERS 

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LINKS

Featured RestaurantGrill House

STUDIES

 Effect of intermittent fasting on diabetic patients-A narrative review

If you enjoyed this episode, please consider leaving us a review in Apple Podcasts!

Original theme composed by Leland Cox, and recomposed by Steve Saunders.


Our content does not constitute an attempt to practice medicine and does not establish a doctor-patient relationship. Please consult a qualified healthcare provider for medical advice and answers to personal health questions.


TRANSCRIPT

(Note: This is generated by AI with 98% accuracy. However, any errors may cause unintended changes in meaning.)



Melanie Avalon
Welcome to Episode 452 of the Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat, with no calorie counting, then this show is for you.

I'm Melanie Avalon, biohacker, founder of AvalonX, and author of What, When, Wine. Lose weight and feel great with paleo-style meals, intermittent fasting, and wine. And I'm joined by my co-hosts, Barry Conrad, actor, singer-songwriter, and creator and host of Banter with B.C. For more on us, check out MelanieAvalon.com and BarryConradOfficial.com. You can submit questions for the show by emailing questions at iapodcast.com or by going to iapodcast.com. We would love to hear from you. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment. So pour yourself a mug of black coffee, a cup of tea, or even a glass of wine if it's that time, and get ready for the Intermittent Fasting Podcast. Hi, everybody, and welcome. This is episode number 452 of the Intermittent Fasting Podcast. I'm Melanie Avalon. I'm here with Barry Conrad. Barry, how are you today?

Barry Conrad
Melanie I'm doing sensational I feel so good I feel I'm having one of those weeks I think multiple weeks of just feeling grateful like gratitude has been the banner over my last few weeks last few days and I just feel really good I feel like I'm in my purpose I feel invigorated I feel inspired I feel excited I feel driven I feel stretched all those things so that's that's a good place to be for me

Melanie Avalon
That is so amazing. I love that.

How are you feeling? I'm feeling good too. And gratitude is such gratitude and laughter can help so many situations. Like if you're already feeling good, it just makes it way even more, you know, high vibration.

But if you're like not in, you know, not in a happy emotion or tension and then you have gratitude or laugh, just helps so much.

Barry Conrad
It really does. It really really does. And also, guess what? I bought my first pumpkin. Halloween pumpkin.

Melanie Avalon
And this is airing, by the way, in December just for listeners.

Barry Conrad
So sorry, listeners, you're already over Halloween, but this is airing, but this is a big deal to me. I've never done the whole Halloween thing properly.

I've got a pumpkin and I didn't carve it out yet, but I did draw on like a scary face. So like a post had to do, but it's, yeah, it's pretty funny.

Melanie Avalon
Okay, so I'm so glad you're saying this because I wanted to talk about pumpkins today, but I was like, this is like a December 15th episode. I don't know if, but maybe we just can and people can be nostalgic.

Did you see my Instagram posts about the pumpkin I carved?

Barry Conrad
No, but I'm about to look at it right now. Should I pull it up right now?

Melanie Avalon
Wait, look, because there's three pumpkins, guess which one is mine.

Barry Conrad
Okay, here we go. Is it on? I'm looking at

Melanie Avalon
page right now I just posted it on my um it's all my stories but it's also my my post my profile whoa whoa what which one is mine

Barry Conrad
Oh, wow, this is okay.

Melanie Avalon
of one of them yours? One of them is, yes. I carved with my sister-in-law and her friend, who is now my friend.

Barry Conrad
Yours is the one on the right, the two with the dresses.

Melanie Avalon
Yes. Do you see what that is? Do you see what it's supposed to be?

Barry Conrad
Is it wicked?

Melanie Avalon
Yes. Do you see it? Can you see it? Like, can you see the wicked vibe?

Barry Conrad
Yeah, it's it's it's clinden alphaba see I score points for me. I actually guessed that that means it's a good carving. It means it's good.

Melanie Avalon
Thank you.

It did not turn out the way I have done better work in the past, but I kept telling everybody, I was like, this is my worst pumpkin I've ever done.

But that's okay.

Because like a key, this is something you'll learn.

Are you, you're going to carve yours?

I'm going to give you some tips.

Barry Conrad
Yeah, because I bought the pumpkin, like, how do you how do people do this? Like, how do you what do you use? You just use a knife because it's pretty intricate what you've done here.

Melanie Avalon
Yeah. Oh, so you know nothing.

Barry Conrad
No, no, no, no, no, no, no, no, no.

Melanie Avalon
Okay, I'll give you a quick, quick lesson. So you get your pumpkin, you decide your what you want to do, which you can either buy like a book with stencils in it, or you can just Google like whatever you want. Google, like I googled wicked silhouette, and then silhouettes will give you something that will work. Because you need it to be where you can like cut it out, you know, and it shines through. So then you get your stencil. And then you so I did it, in my opinion, the correct way, you tape it. Okay, actually, before that, cut out the top so that it's like a like a hat. And then you like pop up the top like pop. And then you scrape out everything inside. And you get it really good and scraped out and clean. And then you take your stencil and you tape it to the front. And then you can get like a pumpkin carving kit on Amazon. And you use the pointy piece that's kind of like a toothpick. And you go and you poke the outline of the like through the paper into the pumpkin, the entire outline of everything, then you remove the paper, and then you get the carving utensils and you carve out the pieces. But you need to make sure this is what my mind got messed up because there's like a key piece missing that fell off, like fell off that would have made their silhouettes more like they were they're supposed to be holding hands, but that piece fell out. So you have to be very careful.

Barry Conrad
It looks very impressive. I'm not going to like that.

Like even the bottom of the coat or the dress that dresses they're wearing, it's very like fine. Like how do you do that without it all kind of getting messed up?

Melanie Avalon
You gotta have the pumpkin carving kit that has a fine-toothed knife thing, and you gotta do the poking the holes around the outline.

Barry Conrad
I didn't know this was a thing, like a pumpkin carving kit. What? I thought people just kind of went to town and just did it, like, and just kind of... That's...

Melanie Avalon
That's what some people do, but ... Did you see mine last year?

Barry Conrad
No, now I want to see what did you do last year. I probably did, but can you say that to me?

Melanie Avalon
Let me send it to you hold on last year. I'm like really proud of it

Barry Conrad
I need to write this down. So, you know, when you, when you take everything out of the pumpkin, do you have to wash it because how does it stay?

Melanie Avalon
Oh, that's the other thing.

So and I was talking with my friends about this, and I'm sending you right now the one from last year.

It's a video but you'll see like you'll see right away mine.

So in my childhood, we would like carve these and they would just like last all season.

But they don't last long.

Mine's like dead already and I did it last night.

Well, it just gets old.

Barry Conrad
Mank, like what happens to it?

Melanie Avalon
It like shrivels up and maybe, you know, it's probably more a problem when you do intricate details like mine. Apparently you can do like a whole thing where you, it'll make it last longer where you like soak it in water and like put some bleach. I don't know. I, I realized this too late. So next year I'm going to try that.

Barry Conrad
Melanie I'm looking at this video and how did you do the Taylor's how did you do the writing the Taylor Swift signature yeah

Melanie Avalon
Yeah, it's so thin. How did you do it? Well, the kit that has the precision saws.

Barry Conrad
Oh, now I see the Stenzel. Now you held up the Lana Del Rey one.

Melanie Avalon
Oh, yeah, because Danielle, Danielle, for that one. So last year, Danielle wanted to do Lana Del Rey and she didn't think it through. She didn't think through that, like, the stencil, what she was cutting out had nothing connecting it to the outer rim. So when she did it, there was nothing. It was just a circle because everything fell out.

Uh-oh. Yeah. You have to, if you're doing your own, like, silhouette stencils, you got to think through, like, is there something? Is there architecture supporting the image?

Barry Conrad
Oh, I just got my pumpkin 101 just then.

Melanie Avalon
I know, that's why I'm here. It's funny because I thought like, I thought I was like, do they do this in Australia? I don't know.

Barry Conrad
I was going to say as well because I went to a like a gathering with some friends the other night and had meatloaf for the first time as well.

Melanie Avalon
Meatloaf. Okay, I am so excited to hear because I don't know what I don't know. So I don't know what we have here that you don't know. So you have to every time you have to tell me I expect every week a new American finding from you.

So we got two this week. We got pumpkins and meatloaf. Okay, so meatloaf. How was it?

Barry Conrad
It was amazing and it sounds like a basic thing like you know but it's so it tasted so good and it was spicy the way this person made it like with extra spices was incredible and then also you you probably have soup with grilled cheese is that a thing that you guys do.

Melanie Avalon
Like tomato soup and grilled cheese? Yeah, yes. That's what we had. Yeah, wow. All-American meal.

Barry Conrad
Yes, we started with that and then had the meatloaf for like the, I guess, the main situation. But yeah, I've never had that combination in my entire life, ever.

Melanie Avalon
So do you know the thing about meatloaf here, though? No. OK, so it's funny because growing up, meatloaf is like a joke. What I mean is parents feed it to their kids and people have it for dinner, but you're always like meatloaf. It's like nobody likes meatloaf, which makes no sense because it's actually really good.

And then you become an adult and you're like, wait, meatloaf is good. But it's a thing. You could ask any kid, like walk up to a kid and be like, what do you think about meatloaf? And they'll be like, yeah, meatloaf.

Barry Conrad
But that's why I wasn't I wasn't kind of excited to try it. I mean, because I keep seeing that on movies like me love again, but it was actually really good.

Melanie Avalon
Okay, so you do know, you do know.

Barry Conrad
I know about that, but it's actually really good. I'm like, what are people complaining about? It's so tasty.

Melanie Avalon
Yeah, it's kind of a lie, kind of like brussel sprouts. We've talked about this, like brussel sprouts are those, that's like the other food that when you're a kid, you're like thinking it's disgusting, but then you have it and you're like, this is so good.

They are so sweet. I don't know why kids don't like it.

Barry Conrad
Cause like with butter and like, oh, it's just so good. Yum.

And also you guys really get into Halloween here in general. It's really not as it's not like really an Australian thing. You really go all out. I love it so much.

Melanie Avalon
I mean, it makes sense because you got to have the cold season for it, you know, you got to be like I don't know Halloween when it's hot would be strange. Are you gonna dress up?

Barry Conrad
I have to. I have to commemorate this first one. I don't know what I'm going to wear yet. Do you have any ideas of a costume that comes to mind?

Melanie Avalon
Okay. And again, listeners, I'm so sorry. It's December and you're hearing about, wait, wait. Well, first of all, can I tell you my, my Halloween costume epiphany that I had?

Barry Conrad
Yes.

Melanie Avalon
So, wait, so how much do they do, do they do trick-or-treating and stuff in Australia and like costumes and

Barry Conrad
Yeah, yeah, like they do do it, but it's more like it's like an adopted thing from here. It's not It doesn't feel festive.

It doesn't feel like real real Halloween people do do parties and stuff like that But it's not not as much of a thing like the streets and stuff are all done up with Halloween Decorations years and that's not a thing in Australia

Melanie Avalon
Oh, okay. Yeah, we, we go all out. We're all about it.

So here's what I had the realization about. So when you're little, and you're dressing up for Halloween, you want to, you want to be like exactly like the character, like you want the costume that like is the character. Then, when you hit late high school college, I probably shouldn't use this word, you want, you want to be the scandalous version of the character, like the sexy version of the character.

Barry Conrad
I get what you're saying.

Melanie Avalon
Yeah, like, so it's basically like take the costume and then like remove half of it. And that's what you are. And then you get out of that phase and you get back to like where like where I am now and you want to be the real character again. It's like you come full circle.

That's the thing. I think it's the thing. Yeah, I promise you, this is like this is the trajectory that everybody in the US goes through. And if you like are if you like stay in phase two, you might want to think about your choices.

Barry Conrad
I feel like some people, you know, like phase two, they're like, they want to be, you know.

Melanie Avalon
No, no judgment. You can stay in phase two. I just get really excited because I love trying to, like, I love trying to create the actual outfit completely. So it's fine.

Phase two-ers, we can still be friends.

Barry Conrad
Can I guess yours for this year? Yes, please do. Is it, Glinda?

Melanie Avalon
Did you see mine last year?

Barry Conrad
I feel like I saw you, but I always see you wearing amazing dresses and stuff, so I...

Melanie Avalon
Did you see my Glenda costume last year?

Barry Conrad
I feel like I have seen it, now I feel silly.

Melanie Avalon
I wore it recently, so let me, for the whiz, let me send it to you on Instagram again because this relates to the answer that you said in a way. You'll see. Slide on this, I think to the last slide.

Barry Conrad
Oh wow, okay, I have seen this dress and you look amazing. Or not the last, the second to last. Yeah, you look great, I have seen this.

Melanie Avalon
Thank you. So this I worked so hard to find to make like the perfect Glinda from Wicked part one. So Barry, you are correct, sort of. Can you complete your answer?

Barry Conrad
I get what you're gonna say. You're gonna say you worked so hard to recreate Glinda's attire from part one of the Wicked series, but now you're gonna work so hard to create her look from the second movie that's coming out soon.

Melanie Avalon
Yes.

Barry Conrad
Yes.

Melanie Avalon
Yes, and I've been so here's the thing though. I've been working on this for a while.

I couldn't find I couldn't find so like the good thing about the part one was I found like a legit epic dress like stunning. I couldn't find that for part two like that that dress is not out there. So I actually had to buy the costume. So I bought like the actual costume like the Disney license costume, but I'm not hasn't arrived yet. I'm not feeling very confident about what it's going to look like. So I think I'm gonna have to like, do some editing of it, like bedazzle it some more, maybe get it altered, like I'm gonna have to pimp it up.

Barry Conrad
Okay, what's like the three main differences between the first dress and this dress? Like, why is it different? Or how is it different?

Melanie Avalon
Well, have you seen the posters? The first dress is like the stereotypical Glenda from Wizard of Oz, what you think of, but like the movie version.

And the four good one, it's just a different dress. It's like a little bit blue, a little bit purple. It's got these funky shoulder things. It's got sheer sleeves.

Barry Conrad
I see it now. I'm looking at it right now. I can see the post.

Melanie Avalon
So stay tuned because like I said, I'm not feeling confident about what I ordered. But I feel confident that I can fix it up.

Barry Conrad
I feel confident about that too. I actually can't wait to see the big reveal. Do you think you'll post it before Halloween, actual Halloween, or just on the day itself?

Melanie Avalon
actual Halloween. Well, when I go out for Halloween. I can't wait to see it.

Which I Oh, it's too late. Well, I can still promote it in retrospect. I'm going to the sips under the sea at the aquarium. If any friends live in Atlanta, I highly recommend sips under the sea events at the Georgia Aquarium. It is so fun. Everybody go. And there's a lot of events. It's not just Halloween. They do it for like a lot of holidays.

Barry Conrad
Awesome. So sipping wine, I guess sipping any beverages under the sea.

Melanie Avalon
Yeah, your tickets include drinks and then you get to see the aquarium without children everywhere and there's like a dance party.

Barry Conrad
A dance party in the aquarium!

Melanie Avalon
Uh-huh and they decorate the whole aquarium and it looks like Epic i'll send you after this a video a reel and some reels It's so cool and everybody's dressed up and then you're with the fishes drinking with the fishes.

They're drinking the Because they're in the water. Everybody's got liquid

Barry Conrad
Everyone's drinking and sliding, I'm sure, after drinking too.

Melanie Avalon
Wait, do fish drink? Oh, wait, wait, whoa, they don't. Do they?

Barry Conrad
Yeah, but their mouths are open. Hold on. They have to be.

Melanie Avalon
I have never thought about this in my entire life. Wait, oh my gosh, hold on. Let me look this up. I'm looking it up. Why didn't they teach us this in school?

Barry Conrad
Do fish drink? I mean, I always kind of thought, man, they must be really full because they mouse open the whole time.

Melanie Avalon
I bet they do. Saltwater fish constantly lose water from their bodies to stay hydrated. They drink seawater through their mouth and expel the excess salt through cells in their gills and urine.

And then freshwater fish have the opposite problem. The water around them is less salty, so water keeps rushing into them. They don't need to drink. Oh, they urinate a lot to get rid of the excess water. Whoa. So they, whoa. So water gets absorbed into their body and they like flush it out. They urinate it out.

Barry Conrad
Oh, okay. Well, I didn't. Yeah. I mean, I never thought about this before. Yeah, it's weird. Yeah.

Melanie Avalon
Wow. But saltwater fish do drink. Whoa. My mind is so blown. Should we get into fasting stuff?

Barry Conrad
I think we should let's jump into some fasting stuff and have a drink of some fasting.

Melanie Avalon
Oh my goodness. I'm making a note though about this fish fact, because that's for my mind blown podcast. That's mind blowing. I never knew that.

Happy December, friends. Berry. Happy almost Christmas. Do you have a study to start us off with?

Barry Conrad
I do have a study, and this week's study that I brought is called The Effect of Intaminifasting on Diabetic Patients, and it was carried out at AIMS in Telangana, India. It was just published actually last month.

Well, actually, this is in the future, so in September 2025 in the Journal of Family Medicine and Primary Care, which is a respected peer-reviewed journal run by Walter Kluwer. This is actually a narrative review. So, the authors went through dozens of clinical studies, both randomized trials, controlled trials and meta-analysis to piece together what we actually know about fasting and diabetes across both type 1 and type 2. So it's not just one experiment, it's more of a bigger picture to look at all the signs so far. So, the main question that they wanted to answer was pretty simple. How does IF, intermittent fasting, affect people with diabetes? Specifically, their blood sugar, their weight, their insulin sensitivity. So what are the real-world risks? What are the benefits? So, across a lot of the studies that they reviewed, intermittent fasting clearly helped with type 2 diabetes. The people with that lose weight and improve blood sugar and control. One clinical trial showed that after six months, people with obesity and type 2 diabetes lost about 3.6% of their body weight with IF, which is crazy. While those on standard calorie restriction didn't lose much at all. So both groups improved blood sugar levels, but the fasting group found their plan much easier to stick with, which honestly, I think is half the battle as well, rather than trying to stick to a diet. Another randomized trial compared to fasting schedules, so 16.8 and 14.10, actually, against a normal diet in a 99 diabetic adult. And the results that they found was the 16.8 group lost about 4% of their body weight, and they saw better HPA1c scores and even improved cholesterol levels compared to the control group, which is pretty powerful from simply changing when you eat, not what you eat. They also included a massive 405-person study from China comparing a 5.2 fasting meal replacement plan with diabetes medications like Metformin and Empelophosin. After 16 weeks, the fasting group dropped nearly 10 kgs, which is more than either medication achieved and lowered their A1c by about 1.9%, a clinically meaningful improvement. So overall, when they looked across these trials, the fasting consistently reduced fasting glucose, insulin resistance, waist size, even improved lipid levels, things like triglycerides and total cholesterol. Basically, it wasn't just helping with blood sugar, it was tackling the whole metabolic picture. But of course, there's always cautions as well. The authors made it very clear that fasting for people with type 1 diabetes or anyone using insulin or certain blood sugar lowering medications, they should really seek doctor's advice because it could be risky.

Barry Conrad
Hypoglycemia, low blood sugar, is a big concern, so along with dehydration of dizziness if fasting isn't managed carefully, that could be really bad.

So for people with type 2 diabetes, though, when it's done under medical supervision, the benefits generally outweigh the risks.

So what's the take-away?

Basically, it's basically saying that intermittent fasting is one of the most promising low-cost lifestyle-based tools that we have for managing type 2 diabetes and it improves our insulin sensitivity, trums our body fat, helps stabilize our blood sugar, but again, it's not one size fits all.

So for anyone with diabetes out there who's thinking about trying it, the message is pretty clear.

Do it with guidance.

But when it's done safely, the science is saying time and time again, fasting can help your body work with insulin instead of constantly fighting against it.

And I think that's a pretty empowering message for listeners living with diabetes now.

It's a lifestyle shift that's not just a diet of the month.

Do you have any thoughts?

Melanie Avalon
Awesome. I love this so much. Quick question. So the one they were talking about where they looked at 16.8 and then you said 14.10, did they only find benefits for 16.8 but not 14.10, do you know?

Barry Conrad
Yeah, so they mentioned just the results that the 16A group lost around 4% of their body weight and saw the better HPA1Cs, but they didn't actually mention here anything about the 1410 per se.

Melanie Avalon
I wonder if that means they only found benefits with the slightly longer fast, you know, compared to the... Yeah. I was thinking the same. That's really interesting. Either way, like what I love about this is, you know, a lot of people turn to intermittent fasting to deal with blood sugar control and type 2 diabetes, but then there's all these other benefits that you get. It's kind of like whatever benefit you come to intermittent fasting for, it's just so awesome that you get all these other ones, you know, looped in with it, which is amazing.

And I also think people... I just feel like it's so common that people... I mean, it is common. It's very common that people get diagnosed with, you know, pre-diabetes and then eventually type 2 diabetes, which is really sad. And that can... I think really feels like a death sentence for a lot of people, like it's like, oh, once you hit type 2 diabetes, now you're type 2 diabetic for the vibe is that you're that for the rest of your life. Like that's the sentence, now you are a type 2 diabetic. And if you reduce your blood sugar levels, it just means that you're, you know, mitigating your type 2 diabetes. When reframe, you know, it's quite possible that with dietary changes and intermittent fasting that you could lower your blood sugars, lower your HBA1C, no longer be in the type 2 diabetes range and, you know, like be in remission, like actually not be type 2 diabetic. So there's just so much power that comes with this.

Barry Conrad
I love it. I totally agree.

There's so much more going on inside our bodies that people don't realize if they don't know much about intermittent fasting. It's not just to lose weight. That's one part of the whole picture. There's so much, so many benefits. It's amazing, actually.

Melanie Avalon
Yeah, I love it. So great find. And I'm glad that they're doing more reviews like this, where they're looking at all this data and pulling out the common findings.

And actually reminds me of something I actually wanted to talk about because I got my results. I know you recently got back to the US. Did you send off your blood test for superpower?

Barry Conrad
I didn't, no, I did not yet. No, I need, I haven't, no.

Melanie Avalon
So I did and I got back my results and this just reminded me of it because like lab work and stuff. I am so impressed with all of the data that it covers. It gives you so many, well it gives you so many things that you should be testing but then on top of that it gives you all of these calculated ratios that help you interpret the data. It's really, I'm like very, very happy with it and impressed.

So just a quick shout out to Superpower. If listeners are looking for a good resource to get really comprehensive blood work at an affordable price with a lot of results and then interpretations and you can actually like talk with them to understand things more, I highly recommend it.

Barry Conrad
I really want to check the I'll check my deliveries and because I surely would have gotten up and I really want to do it now.

Melanie Avalon
It's an email code that I emailed you. So you just scheduled, I think it's like super easy.

You just schedule, you like sign up on the platform and then you schedule out a quest location and quest locations are like everywhere. And then you just go in for your blood draw and then you see Breezy.

Barry Conrad
I can't wait to hear what you like, what yours was and what you found and what was surprising. What wasn't surprising.

Melanie Avalon
So to get their special price, which it's $1.99 and you get this, which is just so good for all of this blood work.

To get their special price, which is $1.99, which is amazing, just go to superpower.com. Oh, and it also gives you your biological age. And I know we've talked about this a lot and that there's a lot of different formulas and ways that people calculate it. But I felt pretty good about mine.

I'll tell you what mine was.

Barry Conrad
I can't wait. I can't wait to this.

Actually talking about the biological age is fascinating to me because there are probably a lot of differing results out there with different companies. So I'm really I can't wait to try this one and to find out what mine is.

Melanie Avalon
I know I'm, I'm really, really excited to see what yours is. And one second, I'm just logging in.

Barry Conrad
Were you nervous to find out yours or were you like feeling anticipation or did you guess what it would be or?

Melanie Avalon
So honestly, yes and no, there's just so many, like I said, so many different ones out there that I don't know how much, I don't know how much weight I actually put in it just because there are so many different ones out there. So basically, it works my favor where it's like, oh, if I get a low one, I'll feel good about that. But if I don't, maybe this is just me like wanting to feel better about myself. But like my, the scores I got so much, you get like a superpower score, which is like how healthy you are out of 100. So I got an 88, which was you're very healthy, keep going. So that's good.

And the biological age, it said I was 7.8 years younger. That was fun. That's crazy. Oh, it also shows your your pace of aging, which is cool. And just so many, especially like people are interested in cholesterol, you get so many markers, you get total cholesterol, LDL, HDL, triglycerides, APO-B, LDL-HDL ratio, non HDL cholesterol, TYG index, cholesterol HDL ratio, and then like a million other ratios calculated like neutrophil to HDL, uric acid to HDL. There's literally dozens more LDL to total, LDL-C to APO-B. Like these are things like non HDL total cholesterol ratio. There's literally like a dozen more triglyceride HDL molar ratio. And what I really like about it too is when you click on anything because it's this can sound really overwhelming. It gives you a very easy to understand explanation of what it is. Yeah, it's really, really cool. So highly recommend.

Barry Conrad
I'll get onto it, I'll get onto it.

Melanie Avalon
Yes, please do, because I really want to know. All right, shall we jump into some listener questions for today?

Barry Conrad
I think we should. Let's do it.

Anna on Facebook says, talk about ADF, please. The up days, how to best support the down days. When is best to work out? In brackets, cardio, strength, if modified fast, 500 calories. When within the fast is it best? What foods? What if you have a special occasion on a down day? How do you catch up? Melanie, what do you reckon?

Melanie Avalon
Awesome.

Okay.

Anna, such great questions.

Okay.

So ADF, it's alternate day fasting.

And there are different ways that people do this, but it's basically where some days per week you eat normally.

And then some days you either do a complete like zero calorie fast, or you can do a modified fast where you have around 500 calories, which is kind of what she's referring to when she talks about, yeah, she talks about the modified fast.

And the thing about ADF is there is a lot of research on it.

It's one, it was probably one of the most studied forms of fasting, especially because it was something that was studied for quite a while before the more, I feel like it was like one of the first like studied protocols, because it's something that they can, it's very easy to do like a protocol to be studied.

The thing is, there's a, like I said, a lot of different ways you can do it.

So you really have to find what works for you.

So like, for me, if I were to do it, because there aren't hard, hard rules about everything.

So like the modified fast day, the 500 calories, there's no rules around that.

Like you could eat that slowly throughout the day, you could have it all at once, like a one meal a day.

Like for me, if I were to do an ADF type situation, I would want to on the fat on the modified fasting day, if I were to do that, I would want to have all my 500 calories at once, probably have just like pure protein, because then I could still eat like a, you know, I would probably be full, like I could still have my one meal a day and eat like a lot of chicken, and at least not be completely, you know, starving.

On the other hand, you might want to hack it to get a low protein day because we do know there are some benefits to having very low protein days, which would happen if you did a complete fast that day, or you might with that 500 calories want to actually do like no protein, which will kind of be similar to what you eat on a fasting mimicking diet.

And that would be it just depends on like, what are your goals?

What is sustainable for you?

Like for me, a complete fast, I just can't sleep well.

So I know that doesn't work for me.

But if that works for you, I mean, more power for more power to you go for it, as far as how to work out strength or cardio.

So I have different recommendations here.

So I think low intensity cardio is great for the fasting days, because that's going to, you're going to be in a fat burning mode anyway with the fasting and low intensity cardio.

So we're talking about like going on walks and things like that.

That's going to help you burn more fat, it's going to help mitigate hunger.

It's not going to create a need for, you know, a stimulus for muscle building, you're not you're not you're not doing that.

So you don't want it, you don't have to worry about, you know, getting a lot of protein to replenish that.

But then again, like I was saying, if you did like a modified fast, you could definitely get enough protein and 500 calories worth too, if you were to do some sort of strength training, but I probably wouldn't like I probably would do the the lower intensity exercise on the fasting days.

Melanie Avalon
And then on your normal days, that's when you could do more strength training, high intensity cardio, things like that. And then if you she's talking about you know what to do if you she said if you have a special occasion on a down day, how do you catch up? So like on a fasting day, what are you going to do if you have a special occasion? If it's okay.

So this is me being being real, like how many? Like, what do you mean by special occasion? So if you're talking about things like your birthday, or Thanksgiving, or Christmas, don't do a down day on those days, like modify, like change around your, your ADF schedule so that you're just not having a down day that day. But I don't know what you mean by special occasion, you might be considering just going out to dinner being a special occasion, and maybe you're doing that weekly. And so now it's more a thing where you actually need to adjust for something that's more consistent. If that's the case, I would look at your overall approach to ADF like are you doing it where you're doing the exact same days, every week? And if so, maybe just switch around the days that you're, that you're doing it for. If it's already like up in the air anyways, then that works even better because you could just, you know, make it match your social schedule. Or you could just not have as many down days that week. Like that's totally fine too. It's more about the consistency over time rather than just one day off plan. And if anything, you know, mixing things up here and there can, I think really help the body keep it guessing and things like that. You could also make another day that like normally would have been a complete up day where you're eating normally, make it maybe like a half, a half day, like a half fast day. So maybe like that day you do a one meal a day type fasting schedule, but you don't restrict your calories. So then it's kind of like you're throwing in like an extra fasting day without taking away from your, how do I say this? So if you cancel out the down day, add in your special occasion, and then turn an up day into like a modified fast, but still eat as much as you want in your eating window. It's kind of like mitigating it a little bit by adding some extra benefits in other days. I don't know if I'm making sense. The point is I think you can be flexible and do what works for you. And I wouldn't, I wouldn't overstress about the occasional one off situation where things get, you know, go a little bit differently. So what are your thoughts, Barry?

Barry Conrad
Melanie, that was so comprehensive and you covered so much there and so many of the things that I was thinking as well. And first of all, thank you for the question. And I love that you brought it up because someone actually asked me this week about ADF. And so this is really timely. I don't personally do ADF, but I have tried it before just to see what all the fuss was about, if I'd like it, if I'd find it easy or hard. I did the modified fast, that modified down there. So I did, I didn't stick to 500 completely. I did more 650, but same, same. I do think the first thing that jumped out to me when you said special occasion was exactly what you said, Mel. Is it a birthday? Is it a wedding? Is it a Christmas? Because if that's the case, the beauty of fasting is you can just work it around your life. So I wouldn't stress. Just, well, I wouldn't stress about that at all.

But I don't, we don't know what you mean by that. So we'd love to know a bit more. For me, I'd say for workouts, I'd follow the same principle. Like, you know, train when you've got energy. I personally train fasted. I love the focus and lightness it gives, but I'd keep lighter on the low calorie days. So exactly what Mel was saying, like walking or stretching or mobility work, and then go heavier on the up days, you know, when you're, when you've got a bit more to burn.

For the special occasions, again, like I'm all about flexibility. If life throws you a dinner on a celebratory moment, I like what you said, Mel, about making it even like a modified update as well, because that way you can still get a good fast in there and not stress too much about what you're eating. I think that's a really great idea. And a lot of the time when I talk to people who do do ADF, is that the updates are actually really where the magic does happen. So if you're fueling your body properly there, Anna, good protein, healthy fats, real food, it does make the down days easier. I really do believe that.

And even when you've, even when I'm fasting 20 hours a day, it's the same thing when I'm fueled probably. So your body doesn't feel deprived in those down days, it's going to feel more supported. So making sure you're replenishing your fuels with good nutrition is really important. So you can set the stage for the next fasting day.

Melanie Avalon
When you did your, when you experimented with it and you said you had like 600 calories or so, did you do it like I was saying, like a lot of protein in a one meal a day situation or did you have it throughout the day?

Barry Conrad
There's no way I definitely didn't do it throughout the day because I kind of thought as well my understanding of it because you're right there aren't that many parameters around like when you can do it like you can eat all day I just didn't want to go so I just had like one meal a day vibes.

Melanie Avalon
which you can you can eat like a lot of meat for, you know, like 600 calories. Awesome.

Barry Conrad
So just like chicken and chicken and beef and I felt pretty satiated.

Melanie Avalon
But then again, it's like, I'm actually, I'm really curious. It's like, if I were to do it, I almost might want to do the low protein thing just for that, like that protein fasting concept, but I'm on the fence.

I don't think I'll ever actually do it practically because I need my big meal every night. I just, life's too short for me.

Barry Conrad
It's too short. It's even, it's sort of like, even like the P protein modified spare sparing diet kind of situation as well. That's sort of like someone to that then.

Melanie Avalon
Yeah, like a protein sparing modified vest. Yeah, pretty much. Okie dokie.

Barry Conrad
Thanks for your question Anna.

Melanie Avalon
Yes, thank you, Anna. Shall we go on to our next question?

Let's do it. Okay, so these questions are from Teresa and she says, okay, so my favorite parts of the episodes are the beginning and end. Yay. I love hearing the two of you catch up on each other's lives and have random conversations and also enjoy hearing your take on different restaurants when you break your fast. So these questions aren't really fasting or scientific, they're more AMA. Number one, with both of you having acting experiences, which movie or TV show would you love to star in and which role would you play? Perhaps it might be fun if Mel chooses Barry's and vice versa. Example, Mel plays Serena from Gossip Girl. I've never seen the show, just an example. Yeah, so should we pick for the other person or pick for ourselves first?

Barry Conrad
Let's pick for the other person first, I reckon.

Melanie Avalon
Okay. Okay. Well, so I'm going to cheat because I want us to both be in the same shell.

Barry Conrad
That's a good call. Yes.

Melanie Avalon
I win, and the show I'm picking is Star Trek, Strange New Worlds. I want to be in a Star Trek, or does it have to be that show? I want to be in a Star Trek series.

Barry Conrad
I don't think you've ever told me this before, this is new information.

Melanie Avalon
Oh, really? Yeah, I would love to be in a Star Trek series so bad. That would be everything to me. I'm obsessed with Star Trek.

Barry Conrad
Would you have like a character like a type of look or character that you'd like within the Star Trek?

Melanie Avalon
Yeah, I would want to be, well, Nurse Chapel is already taken. I would have wanted to be Nurse Chapel in Strange New World.

I would like to be if they have Yeoman Rand, if they make her character bigger and integrate. She's like really the only like blonde from the original series that was young, that was kind of reoccurring. She was only in, I don't know, she's probably only in like five episodes, but they could turn her into a bigger character. Or it could be like a completely new Star Trek series where it's not original characters. And then I'll just be, you know, I don't know what I'll be, but I'll be somebody new.

Barry Conrad
Can you tell me the name of that nurse again?

Melanie Avalon
Yeoman Rand, it's like Yeoman, like the type of Sarge, like what she is, and then Rand is her last name. Because

Barry Conrad
You know Nurse Chapel in Stranger New Worlds, she, her name is Jess and she's, we're like the same agent. She's like Aussie. She's an Aussie.

Melanie Avalon
Oh, she is?

Barry Conrad
Yeah.

Melanie Avalon
Oh my gosh, I didn't know that, she's killing it.

Barry Conrad
I could see you doing a role like that.

Melanie Avalon
Yeah, and then you can be whatever you want to be.

Barry Conrad
I don't know. I don't know enough Star Trek lore to have a fully informed opinion. Who do you think I'd play on Star Trek?

Melanie Avalon
We might have to take one of the original series episodes and do a spin off.

Barry Conrad
Yeah. We'll like write a whole new, you will do a spinoff of our own one. We can lead the charge.

Melanie Avalon
I know what we could do. There's this episode called Who Mourns for Adonis, and the theory or the plot is that they go on this planet where it's like all the ancient Greek gods, because they find out the ancient Greek gods actually were like aliens who visited Earth. But then they actually thought they were gods because of how they were treated on Earth and such. So you could be one of the gods.

We could be on that planet. We could be the gods on that planet, and we could interact with the Star Trek people.

Barry Conrad
I'd be all for that. And then we could have like, you know.

Melanie Avalon
You could be Adonis.

Barry Conrad
I could be a donut, that sounds a feeling. And then we can like eat in space. We can drink in space, the whole thing. That's a big part of it.

So how about you? What's your, I also thought for you, Mel, like an Emily in Paris type five, I could totally see you doing that. I could totally see you doing that kind of character.

Melanie Avalon
We've talked about this before. We could have done that show.

Barry Conrad
We could have done that show. We can do that show.

I see you. I think, listeners, I actually told, well, Teresa, actually, I should say, when I first watched it on Netflix, I told Melanie on one of our calls that she reminded me of Melanie. Do people say that to you?

Melanie Avalon
Nobody's ever really said that to me, but I remember when he said that. I think it's her personality. I agree.

Like when I watched it, I'm like, yeah, that's how I would act pretty much. Yeah, that tracks.

Barry Conrad
So, I can see you doing something, or even like the marvellous Mrs. Maisel, have you seen that? She's got that quick fire delivery, like blend of brain, and yeah, she's awesome.

Melanie Avalon
I think my sister was like really liked that show. Yeah. What would you want to be if you could pick?

Barry Conrad
You know what? I love, like, have you seen that show Paradise?

Melanie Avalon
Oh, this was movie too. I'm throwing Lord of the Rings in there.

Barry Conrad
a movie as well. Oh, if it's a movie, X-Men, let's do it. Marvel. I'd be Marvel here.

Melanie Avalon
And I have to re-answer, because Barry needs to be a superhero in something. Like, he just has to. You have to.

Barry Conrad
I really would love, like, that's like a dream. I would love it to be in a superhero movie, like especially a Marvel superhero movie.

Melanie Avalon
You have to, this has to happen.

Barry Conrad
It has to happen, we're putting in the universe.

Melanie Avalon
Are you listening? Yeah. And what's paradise?

Barry Conrad
Paradise is such a good, it's like a really like good dramatic show. We're still in Cape Brown and basically the American and a lot of the world gets blown up and there's this like world that's built underneath the earth.

It's like a whole like, it's like a simulation. Like it's almost like, is it like post-apocalyptic stuff? Yeah, post-apocalyptic, but like the world that they build is like so serene and placid and like beautiful and, but it's all like not real, but people, yeah, it's actually like, I think you'd actually like it because it's very much like simulation vibes.

Melanie Avalon
Nice. I can see you there. You'd be there.

Barry Conrad
Cause it's also like he's like a, you know, he's like a, you know, he's physical. He's like, goes after the bad guys. It's awesome. It's fun. Good dramatic character.

Melanie Avalon
Awesome. Well, I'm excited. I can't wait to see your next thing, whatever it is that you're gonna be in.

Barry Conrad
Yeah, and I can't wait to see us both on Star Trek.

Melanie Avalon
Yes. We could save Teresa's next two questions for next week. Should we do that? Especially because I think the first one, the next one does involve...

Barry Conrad
Yes. So Teresa, stay tuned for part two.

Melanie Avalon
All right. And speaking of, so she was mentioning that she likes when we do our proverbial breaking of the fast restaurant exploration. So shall we do that now?

Barry Conrad
Let's do that. And you know what, Mel, I have to actually say that I love getting that feedback that people, just different parts of the show that people enjoy.

Like it's so, it means a lot to us. So thanks for, thanks for listening, everyone.

Melanie Avalon
Yeah, I got I got really excited because we got this one and then I got an email that I sent you that was yesterday. And then I also saw a similar comment, I think, in the Facebook group about people liking like the restaurant stuff and the banter and such. So, yay, let us know what you guys like, what you would like more of. We are happy to try to make everybody happy, which is not possible, but we try.

OK, so this I'm continuing like I was on my haunted restaurant streak. So let me get the one I'm going to do because last time I did my hundred hundred restaurant, I said I had four. We did one. And then I said the next one I was going to do that they had kind of like an interesting set up.

Barry Conrad
You did say that, so I'm in suspense now. So I'm like, what is it?

Melanie Avalon
So let me tell you about it. Okay, this is called the Grill House, and it was built in 1836, and it kind of looks like a barn house, and it's in Michigan. So it has like an old-fashioned country aesthetic, and it has its unique concept, which I'm going to tell you, but the legend about it is that a local lumberjack died in a knife fight on the property and was buried in an unmarked grave somewhere in the yard. Witnesses claim to have seen the lumberjack spirit around the property, but the good news is he is a friendly presence, and it's considered one of the most haunted restaurants in the country.

So, Phantom Lumberjacks looks like a barn, but the setup is it has this massive grill, and you diners, you grill the meat yourself. So let me like, let me, let me, I need the link.

Barry Conrad
I need to see this situation. This sounds very interesting for sure, the setup.

Melanie Avalon
So here it is.

Barry Conrad
He's a friendly, he's a friendly ghost.

Melanie Avalon
He's a friendly lumberjack phantom. We love that.

Barry Conrad
Okay, it's good. Looking at it now, here we go. Where you become the grill master. That's like the...

Melanie Avalon
Oh, they have a holiday wine tasting Friday, November 7th, we should go.

Barry Conrad
Also, the food looks pretty good so far.

Melanie Avalon
So it's not really my vibe and that it's a casual dining experience and I love, you know Fancy schmancy, but I really like this grill master experience So do you see that did you just go down and see the big grill that's in the center? So there's a they have a large 30 person grill 30 person grill and you go up with your group So it starts you hand select your favorite steak.

Then you go to the grill And you grill it and then you eat it

Barry Conrad
I'm picturing you doing it and you just throw it in for like one second because you like yours blue.

Melanie Avalon
I'm done. I wonder if they like monitor, it says they have grill masters that assist you with cooking times.

Can you imagine me getting kicked out? Like I just like put it on for like a second. They're like, ma'am, ma'am, you have to, nope.

Barry Conrad
It's our safety rules you have to, you can't do it for like a second, you have to.

Melanie Avalon
Sorry, sorry. And so the way the entrees come, so all entrees include a bottomless bowl of family-style house salad with balsamic vinaigrette dressing. Would you eat any of that? Yeah, yeah.

That sounds good. How about the sides? Unlimited sides are baked potato with butter, sour cream, green onion, cheese, and then baked beans, caramelized onions, and Texas toast. What would you eat from the sides?

Barry Conrad
Oh, I would do the big potato. I'm not really a beans kind of guy. Are you a beans person? No. No, no, no. You told me this actually or not. I prefer a big potato all day.

Melanie Avalon
Especially baked beans. Have you had baked beans? They're so sweet. They're like sugar.

Barry Conrad
You know, in Australia, it's like beans on toast, baked beans on toast is a thing.

Melanie Avalon
Oh really? Kind of like our grilled cheese tomato soup situation?

Barry Conrad
Yeah, but yours, that's way tastier than just baked beans and toast.

Melanie Avalon
Is it and it's the baked beans like they're like sweet right aren't baked beans really sweet

Barry Conrad
Yeah, they're looking like a tomato sauce kind of thing and you just take it out of a can and slap it on the bread and eat it.

Melanie Avalon
Am I thinking of something different? I'm thinking of the beans that are really, really sweet. Yeah. We probably make them sweeter here, though, in the US.

Barry Conrad
Yeah, that tracks.

Melanie Avalon
So, okay, so would you eat any of the Texas toast? I might taste the caramelized onions, maybe.

Barry Conrad
You know what, I think I'd taste the onions over the beans. So yeah, I'd have some of the onions. That sounds good.

Melanie Avalon
and then you pick what you're actually grilling. So what would you get? There's so many things.

Barry Conrad
So grill room menu. So I would... Man, there's actually so many options for sure. I'm going to take several things. I'm definitely going to do shrimp dinner.

I know it's not meat first. I'm going to do the shrimp dinner. I'm going to do... Oh, wow. The American wagyu steak with rich buttery texture. That looks good too. Probably those two, that one and the shrimp. What about you?

Melanie Avalon
I think I would get a bacon wrapped filet mignon, also the shrimp dinner, also I think I want to throw in some chicken breasts.

Barry Conrad
I was looking at that as well. I'll do that too.

Melanie Avalon
We could just have a meat fest.

Barry Conrad
It's going to be a protein fest, yeah. I love that idea. Even if you're pretty much going to walk up to the grill mill and just turn around again, except with the chicken, you have to cook that.

Melanie Avalon
I know, I would probably, yeah, oh my goodness. We could also get like a strip just to like, you know, I don't know, I just want more meat.

Barry Conrad
Yeah, it's so more-ish, I reckon.

Melanie Avalon
And then we can look for the ghost.

Barry Conrad
Yeah, find the friendly lumberjack and see if he's around.

Melanie Avalon
Yeah, I want to see if they do if they do they talk about the ghost on their website.

Barry Conrad
Surely there's like a bit of a, what if there's like a presentation or if someone says, hey, everyone, welcome, and tells us any stories about them, you know?

Melanie Avalon
It looks like, and they have three different, okay. So there's the grill, okay. So the grill room is like its own room. So I guess you go in there and then there's the rock, which is their inside casual rustic. They would, the original rock walls, oh my goodness. Okay, I love, I have like a thing for original rock walls.

There's this. Really? Yeah, I think it's so cool. When it's like the original walls, it's like, whoa. Cause there's this, there's this restaurant here called Devan, Devan, Devan. I don't even know how you say it. It's right by the symphony. And so we always go, we get drinks before the symphony, or if I'm seeing something at the theater by there, and it's like in this, they call it a castle, but I mean, but it's like the original walls. I just, yeah. Do you know what I'm talking about? I love these.

Barry Conrad
I do know what you're talking about.

Melanie Avalon
Do they have this on Australia? Do they build rock structures in Australia? I can't really see that happening.

Barry Conrad
I do like they do have like cobblestone but like they do have old institutions that like, you know, OG like from, you know, way back in the day and I do like it because you feel the history just feels good, like it feels good to be in those places.

Melanie Avalon
Yeah. And it's like, it's like this rock was here then and it's still here. It's kind of like, have you been to Rome?

Barry Conrad
Yes, I love Rome so much for that reason. You feel, you literally feel the history in the air, right?

Melanie Avalon
It's wild like what's wild about Rome is that there's just like ruins everywhere like it's like a city But then there's like oh, this is from The roman empire and it's just like chilling in the street. Yeah

Barry Conrad
you feel like how many people, how many battles, how many things, how many people walk these same streets I'm walking right now, you know?

Melanie Avalon
Yeah. And then the Coliseum is just like.

Barry Conrad
Ah, the Coliseum is next level. Overwhelming. It is.

Melanie Avalon
Yeah, so that's how we feel about history.

Barry Conrad
We love it. Well, maybe we should try to find something at the Colosseum at some point. I've never actually... I didn't eat there. I don't think there's a... I don't remember there being.

Melanie Avalon
I just remember kind of being like a football stadium, but not.

Barry Conrad
but definitely not.

Melanie Avalon
a drink menu.

Barry Conrad
Beverage and dessert menu, is that the one?

Melanie Avalon
Let's see, this might be a sneak in my wine situation. We'll find out. Let me see, yes, this for me is a sneak in my wine situation.

Barry Conrad
Oh, that's funny. Well, there's non-alcoholic beer with the specialty cocktails. There's white wines, red wines. There's a few things there, no?

Melanie Avalon
uh-huh

Barry Conrad
Not impressed, I'm not convinced.

Melanie Avalon
No? Is there something you see that you like? You could get a cider ready to drink cocktails.

Barry Conrad
I think in a place like this, I kind of almost feel like getting a cider, you know, because it's just, you know, the stone walls and it feels just so like, medieval, you know, that's not a word, guys, but you know, it just feels like old.

Melanie Avalon
Are those spiked ciders? Probably not. No.

Barry Conrad
No, I actually don't like that. No, those, I don't like those.

Melanie Avalon
You could add vodka to the cider or like bourbon. You can make your own drink.

Barry Conrad
Specialty let's see what the specialty co maybe they have a lumberjack cocktail. Let's see do they

Melanie Avalon
I'm sure they do, hopefully, maybe not.

Barry Conrad
Oh, they don't have a friendly lumberjack.

Melanie Avalon
Where is this lumberjack that people speak of?

Barry Conrad
I wonder if there's a photo of what he used to look like or apparently used to look like, surely. Oh, actually, hold on.

There's a grill house, Breeze Martini. You know, I like to try the drink of the place.

Melanie Avalon
Yeah. Or yeah. Mm hmm.

Barry Conrad
So I reckon I'll give that a go. Awesome. What about you?

Melanie Avalon
I'm sneaking in my wine, so we're good there. And can I guess what you want for dessert?

Barry Conrad
You can do this two things and I feel like it's these two things. I think pretty, I'm pretty sure was like two shows ago, the same choices.

Melanie Avalon
You're getting whoa, they have something really fun though. Well, if it's the same as last time then you're getting the cheesecake and the chocolate tort

Barry Conrad
You get, yep, so predictable.

Melanie Avalon
You're not gonna get the peanut butter pie.

Barry Conrad
I also want that because that sounds, that's not like something you see. We don't see that on

Melanie Avalon
on a lot of menus. That sounds very like American too.

Barry Conrad
It actually really does. Can I guess what you'd have?

Melanie Avalon
That's what I would want the most, actually. Oh, I just told you, Ophel. Did you hear me, what I said?

Barry Conrad
You'd want that the most.

Melanie Avalon
Yeah.

Barry Conrad
Yeah.

Melanie Avalon
Mian, would you have guessed that?

Barry Conrad
Well, I was just going to say, I'll just have what I like most from the main.

Melanie Avalon
Oh, right, what I actually would get. Oh, right, right, right. Okay, I thought you were thinking like dream, like, oh yeah, what I actually get, you're right. Yeah, I would just get a repeat of what I'm craving more of, what might be like another filet, maybe some more shrimp.

It'll probably be, I find that once I start eating the meat, I really want more, so probably be some sort of steak. Maybe I'll get the wagyu for dessert.

Barry Conrad
What if they're like, ma'am, you've already grilled, but didn't even really grill you meat and now we're closing it down, you have to have something else. What would you do if you couldn't re-grill?

Melanie Avalon
That's fine. The grill's still hot enough. Like, I can go fast. Like, it's still hot enough, I promise. It's fine. It's gonna be even better, actually.

Barry Conrad
That's so funny. You'll be starting with your tongs like, no, just let me grill it. I know.

Melanie Avalon
I like run. Can you picture this scenario? I can, yes, actually.

Barry Conrad
And the peanut butter pie one day, we will attempt to convince you to have one of these delicious desserts from the dessert menu.

Melanie Avalon
I have no fear. I think it's funny because you're so convinced you're gonna convince me, but nope. You have not met my, I am a wall. I am a rock wall like that they built this out of.

Barry Conrad
But if Funfetti came along...

Melanie Avalon
Even less likely to tempt me because I know how much I like it.

Barry Conrad
I totally forgot, I'm really annoyed because I saw something with Final Fantasy recently and I meant to make a note of it and tell you, but I forgot now.

Melanie Avalon
Was it the sourdough that they released? Yeah, Pillsbury's releasing a sourdough funfetti mix. That's intense. I know. I read a review about it.

Barry Conrad
Of course you did.

Melanie Avalon
Awesome. Well, this was so, so fun. Listeners, we hope you enjoyed your time with us. If you have your own questions for the show, please send them to us. We would absolutely love to hear them.

You can directly email questions at ifodcast.com or you can go to ifodcast.com and you can submit questions there. You can get all the stuff that we like at ifodcast.com slash stuff we like. And you can follow us on Instagram. I am Melanie Avalon. Barry is Barry underscore Conrad. Oh, there's one thing I wanted to say before we go. I meant to say it in the beginning with the Halloween pumpkin carving, but speaking of like drinks and festivities, you might not want to start drinking until you're like almost done with the pumpkin because I found this out last night. What happened? Well, just normally I don't drink at all during it, but then I start, we were all drinking wine and stuff and I was like, Oh, I'm getting a little bit like my skills or I was kind of getting over it more. Like, and I was just like, I'll just cut this here and cut this here. And like, so yeah, I might want to keep that in mind, but no taking.

All right. Well, this was so fun. Anything from you before we go?

Barry Conrad
Thank you so much, listeners, for tuning in once again. We appreciate you so much and we'll catch you next time.

Melanie Avalon
Awesome talk to you next week

Barry Conrad
Talk to you next week. Bye.

Melanie Avalon
Bye! Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice, and no patient-doctor relationship is formed.

If you enjoyed the show, please consider writing a review on iTunes. We couldn't do this without our amazing team. Editing by podcast doctors, show notes and artwork by Brianna Joyner, and original theme composed by Leland Cox and recomposed by Steve Saunders.

See you next week!

Barry Conrad
you




Aug 26

Episode 436 – IF For Vascular Health, Fasting And Jet Lag, Fasting And Nitric Oxide, Stem Cells Treatments, Vitamin C Serums, Beautycounter’s Return, The Fountain Of Youth, And More!

Intermittent Fasting

Welcome to Episode 436 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, biohacker, founder of AvalonX, and author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine, and Barry Conrad, actor, singer-songwriter, and creator and host of Banter with BC

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LINKS

Featured Restaurant: ⁠Perrone's Restarant and Bar

If you enjoyed this episode, please consider leaving us a review in Apple Podcasts!

Original theme composed by Leland Cox, and recomposed by Steve Saunders.


Our content does not constitute an attempt to practice medicine and does not establish a doctor-patient relationship. Please consult a qualified healthcare provider for medical advice and answers to personal health questions.


TRANSCRIPT

(Note: This is generated by AI with 98% accuracy. However, any errors may cause unintended changes in meaning.)


 
Melanie Avalon
Welcome to Episode 436 of the Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat, with no calorie counting, then this show is for you.

I'm Melanie Avalon, biohacker, founder of AvalonX, and author of What, When, Wine. Lose weight and feel great with paleo-style meals, intermittent fasting, and wine. And I'm joined by my co-hosts, Barry Conrad, actor, singer-songwriter, and creator and host of Banter with BC. For more on us, check out MelanieAvalon.com and BarryConradOfficial.com. You can submit questions for the show by emailing questions at iapodcast.com or by going to iapodcast.com. We would love to hear from you. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine if it's that time, and get ready for the Intermittent Fasting Podcast.

Hi, everybody, and welcome. This is episode number 436 of the Intermittent Fasting Podcast. I'm Melanie Avalon, and I'm here with Barry Conrad.

Barry Conrad
How's it going, everyone? How's it going, Mel? What are you doing? How are you doing?

Melanie Avalon
I am doing so well. Okay, you know, what's funny, I started doing the intro and then I, I couldn't remember if you, I mean, it hasn't been that long since you recorded.

I couldn't remember if I pause and then you say hello, or if I like ask you first. Like I forgot what I was saying, basically.

Barry Conrad
basically listeners, it's my fault because I'm really jetlagged. So my brain, if there's like a delay in any answers, it's because my brain is catching up to the jet lag because I've just officially moved to the United States of America on Saturday night.

Melanie Avalon
This is wild although although okay, so you moved here, but then you're gonna travel back to Australia for your show

Barry Conrad
Yeah, because initially I was looking at, oh, I'm moving in September, but I've officially like moved on the weekend because I'm just going back to our trip in July, you know?

Melanie Avalon
My goodness. This is wild. Yes. How do you feel?

Barry Conrad
Well, as I speak to you right now, I'm looking out over this amazing view of the city. It's just New York City and I cannot believe that I'm here. I feel so grateful, so pumped, so stoked. It's very surreal because we've talked about this Mel, like for ages and now it's happening. I'm actually at the same time as you, which is crazy too.

Melanie Avalon
I know oh my goodness we're like and you know what New York I feel like it feels so far away from me but the flight is not that long I don't think I don't I feel like it's not I feel like it's like shockingly not that long

Barry Conrad
to ATL. This is crazy.

Melanie Avalon
Maybe it's farther. Maybe I'm thinking of something else. Okay, wait, New York City.

Barry Conrad
Let's see. It is really surreal that we're in the same time zone because listeners at the moment, it's 9am, 904am on Wednesday in Australia.

And like we're the day, we're like a day before, which is crazy.

Melanie Avalon
And how many days have you been back officially?

Barry Conrad
So I got in like Saturday evening, so it's been like maybe three days, kind of full days sort of thing.

Melanie Avalon
So we have to talk about all things jet lag. Although before that, so direct flight from Atlanta to New York City, yeah, two hours and 10 minutes, two hours and 10 minutes to two hours and 15 minutes.

That's fast. That is, that is less than Lord of the Rings, like watching Lord of the Rings.

Barry Conrad
That's... I wasn't expecting you to say that, but that's true. Like, go into a shower.

Melanie Avalon
I've realized when it comes to time, anything that's in three-hour time chunks, I measure it by Lord of the Rings. Anything that is 10 minutes, I measure by Taylor Swift's All Too Well, the 10-minute version.

And anything that is 40 minutes, I measure by a TV show for like 20 minutes, like back when there was commercials.

Barry Conrad
Yeah, yeah, totally. Or even like the length of shows now on streaming, it's not that long. So yeah, 20 minutes tracks.

Melanie Avalon
Yeah. And so wait two hours and 10 minutes. That's actually, that's even less than most movies today. I feel, or a lot of movies today.

Barry Conrad
Yeah, it's like I'll just jump into playing and it's that quick. How crazy is that?

Melanie Avalon
Oh my goodness. And this will be, this is old news by the time this airs, but you went to the Tonys, right?

Barry Conrad
i went to the tony awards on sunday night and it was insane so got here saturday my suit just made it because i had a suit customized for the the show and i had to pick it up after landing from this cargo carrier place and so did that sunday afternoon got rid of which the tony awards and it was the most incredible night i can't even put into words how inspired i feel how how many people were there i feel like this is like the best year could have gone like anyone you can think of was like there it was incredible mel

Melanie Avalon
That is insane. Talk about welcome to America. Welcome to New York City. What was your favorite part?

Barry Conrad
Well, Hamilton, the musical, had like a 10-year reunion, so like the cast, the original cast, performed immediately. Yes.

Melanie Avalon
No, I have to watch that. I didn't, I clearly did not watch the Tonys. If I had cable, I would watch. Oh my goodness. That's amazing.

Barry Conrad
And the whole room was like, those goosebumps, everyone was on their feet. It was crazy hysteria when that happened.

And they killed it. And then Cynthia Arevo hosted, she was amazing. Sara Bareilles sang. What did she sing? The Sun Will Come Out Tomorrow, you know, from Annie with Cynthia. They did like the stuette for people that have passed away. It was really beautiful.

Melanie Avalon
I'm seeing Waitress on Friday that she didn't, she write the music for that. Pretty sure. Yeah. That's amazing. Oh my goodness. Who'd you sit by?

Barry Conrad
I just sat with the people that I was invited with, a shout out to Michael Castle Group for making it happen, and basically Michael Castle Group, they had six Tony nominations with the picture of Dorian Gray, which is a play, and they won too, so that's amazing.

Melanie Avalon
Congrats to them. Oh my gosh, do they like go on stage and accept an award?

Barry Conrad
Yes, Sarah snook. I don't know if you know her. She was in succession. She's an Aussie actor, actually, and she's doing it on Broadway right now.

The picture of Dorian Gray and I still have to see it. Apparently, it's crazy, like amazing.

Melanie Avalon
Oh my goodness, that's so amazing. I am so happy for you. I think I was more excited, not more excited, but I think I was almost as excited as you about you going to this.

Barry Conrad
You actually were and you would have actually loved it Mel and just it's such a different culture like everyone loves to celebrate like ambition and being a go-getter and you feel like anything really is possible here which is man just people just come up to you and just say hey I'm so and so here's my number I'd love to help you it's like why you don't even know me I just got here so this is New York you know

Melanie Avalon
That's amazing. So is that a different culture in Australia? Like that vibe is not quite there in the same way?

Barry Conrad
It's not the same because culturally, Australia is more laid back, so if you sort of a go-getter, sometimes that can be like the tall puppy. Have you heard of this thing, the tall puppy syndrome?

Melanie Avalon
Is that like an Australian term? Wait, the tall poppy syndrome. Is that what American Australians call Americans?

Barry Conrad
It's kind of, see if you can guess what that means.

Melanie Avalon
I mean, I'm guessing it means that you're being like, like, look at me, do all the things annoying.

Barry Conrad
Yeah, it's basically like they want you to like, it's more like they'll cut you down and say, Oh, why, why are you doing that? You shouldn't do that. It's too much.

Whereas in America, I feel like generally, very generally speaking, that's, that's more celebrated if you want to get ahead and they love it and people love to collaborate and it's just different that way.

Melanie Avalon
So the tall poppy syndrome is not the person who's, it's the person who cuts the poppies. Yeah, exactly.

Okay, I guess that wrong. I thought the tall poppy syndrome was referring to the, like, the person who's trying to stand tall, but it's referring to the person who cuts them down.

Barry Conrad
Yeah, it's all puppies. But you know what, in saying that, and I'll, I have to be careful, because I do love Australia. It's one of the best places in the world.

I'm not heading on it. It's just a different culture. That's all.

Melanie Avalon
Well, I also think it's not that it's selfish, I think it's two things in America. So it's very much what you're saying where we celebrate ambition and doing all the things and, you know, you can do anything and that's what America is about, which we love that. That's, yes, sign me up.

And I also think because that's the spirit of things that people, not that people are sucking up to each other, but people see that people who are ambition will make it far and people here know that you want to be with people who are ambitious. So it's kind of like, I scratch your back, you scratch mine, but like people want to, it's collaborative and everybody wins. Do you get what I'm saying?

Barry Conrad
Yeah, exactly what you're saying. And I also don't think that's necessarily bad in some cases. Like, you know, I don't think that's a conniving thing. Like, I think it's also like a survival thing.

Melanie Avalon
Oh, yeah, no, so true. It's like, and it's like literally like we just understand the importance of social relationships and, you know, and we and celebrate success.

And I think it's like, appreciated and understood how that all goes together here.

Barry Conrad
I totally agree.

And Melanie, I have to share one thing as well, what a guest, see if you can guess what my very, my very first meal was on Saturday night. And we've talked about this before. So try to think.

Melanie Avalon
Did you go to one of the things?

Barry Conrad
I didn't because I was I was too tired from but ordered in but

Melanie Avalon
That would have been like, that would have been like a lot.

Barry Conrad
Committed to the cause straight from the

Melanie Avalon
I don't even remember which ones we listed, but oh my goodness. You ordered in oysters. Oh, wait, let me think. Okay, wait. So is it something that's specific to America?

Barry Conrad
think about something that I've like gone on and on about that's like this would be like my final meal.

Melanie Avalon
Oh man, I should remember this. Okay, hold on. I should know this.

Barry Conrad
Another clue is it's pretty American. It's not really an Australian thing, really.

Melanie Avalon
Okay. You're going to tell me and I'm going to be like, is it mashed potatoes? Is it pizza? Fried chicken, fried chicken, fried chicken. I got it.

Barry Conrad
Yeah, I had soul food, so fried chicken waffles, mac and cheese, you got it, yeah.

Melanie Avalon
I was going to say mac and cheese too. Okay. Yeah. Okay. I need to like, I need to like list off things and then for it to come to me. So, um, where'd you get the fried chicken from?

Barry Conrad
It's from a place called, I think it's called Sweet Chick and it's like a pretty popular place here. Everyone goes to New York, so I got it from there and it was delicious. I was kind of, in the end, getting tired while I was eating because of the jet lag, but it was so good now.

It was delicious.

Melanie Avalon
oh my goodness wow and speaking of jet lag so how have you how did you okay so how long you you said it's like how many hours from australia to here like how long was that trip total

Barry Conrad
in case of listeners and Melanie, it was first a three and a bit hour flight from Melbourne to Auckland, New Zealand, and then almost 16 hour direct flight from Auckland to New York.

Melanie Avalon
Okay, so how did you so did you fast during any of that? Did you eat? What did you do?

Barry Conrad
I fasted during some of it. I fasted during all of the New Zealand flight and the waiting time and stuff, and then I ate a little bit on the plane, but I instantly regretted it because the food's just not great.

It was a mission, but I'm here now.

Melanie Avalon
Have you been using fasting to reset your circadian rhythm?

Barry Conrad
actually have so that's been really helping a lot so I've really pushed my fast I've done about 20 and a half hours today which is really good that's my first really really long normal normal fast protocol for me today so I feel much better but still getting there what about you what's the longest flight you

Melanie Avalon
Done? Wait, wait, wait. Quick question. So you're going to eat late tonight? You're going to eat after this?

Barry Conrad
So I'll probably have like a little something after this I reckon. I haven't eaten yet.

Melanie Avalon
Wow, you're doing it like Melanie style.

Barry Conrad
You know our shows, we do them in the evening listening, so I'm trying to get that Melanie schedule just to see if I like it, to see if it works with me.

Melanie Avalon
What you could do is, even if you don't like it, you could use it as a, here's my, here's my pitch for you. Are you ready? You ready for my pitch? Okay.

So say you, you could do your normal window every other day. So eat earlier. But then on these days, you could eat after. So that would give you one day a week, like a, a long, like a, that would give you like a, you know, a 36 hour fast or something, right?

Barry Conrad
Yeah, I actually could do that. I could do a long, I could push it.

Melanie Avalon
Yeah, I can see what I'm saying like do your normal thing And then have your one day a week and then you would automatically get a long fast

Barry Conrad
Yeah, just throw it in there like a bonus, you know?

Melanie Avalon
I like it. The problem for me is that I can't, because I already eat late, there's no way for me to do it.

There's no way for me to... The cool thing about the situation with you is you could still eat every day and get in a longer fast. I can't because I eat late, so in order to get 36 hours, I would have to actually go to bed again. I'd have to sleep in an empty stomach, if that makes sense.

Barry Conrad
That's not fun.

Melanie Avalon
Which I don't like doing, but to answer your question, the longest flight, um, I've only, I've only gone to Europe, so Europe stuff. I don't know what's farthest away with, it probably would have, oh, actually Hawaii.

Isn't Hawaii far?

Barry Conrad
How was pretty far, but it depends where you're coming from because I know it's like super far from Australia, but from Atlanta, I'm not too sure

Melanie Avalon
I think now it's like looking up all the, wait, I need to see, I need to see.

Barry Conrad
I feel like the UK would be quite far because you went there for like a Thanksgiving situation.

Melanie Avalon
Yeah, but it wasn't. It wasn't that far. It was only the fight with the flight from Atlanta today was like six something hours

Barry Conrad
Yeah, actually, I was someone told me yesterday, actually, that someone invited me to come to a show in the UK. And they said it's actually like maybe like a seven, eight hour flight, because Singapore to Sydney time travel situations, not that far.

Melanie Avalon
Yeah, it's like shockingly not as far as I thought it was. It looks like Atlanta to Hawaii. Oh, you can take a nonstop?

Barry Conrad
What did you do? Did you, you had connections?

Melanie Avalon
That's mind blowing to me. Yeah, I always thought that you connected like in LA or something. Okay, so it's nine and a half hours if you take a night, if you take a nonstop.

Barry Conrad
That's still not that bad.

Melanie Avalon
No. But then if you connect, then it's like, you know, 13 hours or something.

Welcome to New York. Did you play Taylor Swift's Welcome to New York? I should have sent that to you. Man, should have sent that to you on the day. I should have like played it. I should have sent you a message, a voice message and like played it.

Barry Conrad
Would you have sang it?

Melanie Avalon
No.

Barry Conrad
This conversation, right, about if you can sing really well.

Melanie Avalon
I sang in the past.

Barry Conrad
See, I think once a singer, always a singer. So I'll have, we might have to change that. Maybe I'll get like an exclusive.

Melanie Avalon
You'll get an exclusive performance of me singing. Yeah. Okay. Um, yeah, maybe not. We'll see. Never say never. Never say never.

Barry Conrad
Anyway, what about you? How's your week been? How's your past couple of weeks been?

Melanie Avalon
Well, it's good. I can actually, we have a question that asks about the biohacking conference so I can, I can tell you then about going to the biohacking conference. It sounds great. Perfect.

Okay. But before that, shall we do a study?

Barry Conrad
we should. So I am bringing a study today called Time-Restricted Feeding Improves Vascular Function in Healthy Humans. And it was published in 2024 by researchers at the University of Colorado Boulder and appearing in the journal Atarias, Chlorosis, Thrombosis, and Vascular Biology. And the reason why, Melanie, you know about this story already, but the reason why this hit quite close for me, hit home for me, was because a few years ago, listeners, I had a clot dislodged in my leg and shot up to my right lung. And I essentially had half of my right lung killed off. And it was a moment where it almost passed away. It almost died. And so any time, well, ever since then, I've been really cautious about anything vein or blood flow related.

So when I came across this study, linking intermittent fasting to vascular health, of course, it really appealed to me. And so this study, it involves involve 24 healthy adults aged between 25 and 55, which is not a huge, huge group of people, but the design was pretty solid. So each participant followed a four day control eating pattern first where they ate three meals spread across like a typical regular normal day. And then they switched to four days of early time restricted feeding, where all meals were consumed between 8am and 4pm. And so they were doing a clean love it, the clean 16 eight fast, but then they skewed earlier in the day that time. So what stood out now is that these weren't people with pre-existing issues, the vascular issues, they were healthy, no metabolic diseases, which makes things even more powerful. Because what the researchers saw was a significant improvement in endothelial function after just four days of time, just four days of time restricted eating. So listeners, if you don't know what that means, it's that refers to how well your blood vessels expand and contract. And it's a massive marker of like cardiovascular health. And then when it's impaired, you're looking at way higher risk for things like high blood pressure, heart attack, stroke, and clot formation, which is what happened to me. So the fact that they saw measurable changes in just a few days is awesome. But it gets better too, because they went deeper and looked at nitric oxide availability as well. So that's the molecule in your body uses to relax blood vessels and improve circulation. So after fasting, nitric oxide by availability improved as well. They also saw a reduction in oxidative stress, which is basically cellular damage caused by inflammation or free radicals. And that reduction further supported improved vessel function. So all this from shifting when the people ate, not what they ate, that's the key here. Not how much, just the timing. And I think that's the key takeaway. And there's this deeper layer to fasting, you know, that to a lot of people just goes under the radar, even to people that fast all the time, forgetting that it's not just about those scale victories, you know, it's not just the weight or the glucose or the willpower,

Barry Conrad
it's literally supporting our health, you know, our vascular system. And it's something I take incredibly seriously.

So of course, this was pretty short term and small, as I said before, we need bigger, longer trials to confirm more how long these effects last. But even with the small pilot, I think one thing's pretty clear is when you eat, when we eat matters. And it's just another reminder, Mel, that IF isn't just about the visible stuff. And yeah, it's protecting you from things you might never see coming. Mel, what do you reckon?

Melanie Avalon
Oh my goodness, that is an incredible study. Thank you so much for finding it. And especially sharing your personal relationship to it, it's still so crazy to me that you went through that. And that just must, I don't know, that must give you so much gratitude for life, having been through that.

I think this is really, really powerful, especially because cardiovascular disease is the number one killer of people in general. I was just reading about it more the other day in a book and it was saying how pretty much, not that everybody gets it, but everybody pretty much when you die, you have some level of approaching cardiovascular disease just because of how prevalent it is and how it happens in the body. And so seeing, like reading the study, that's amazing that after only four days that they saw those effects. And then it's not just, you know, cardiovascular, anything that benefits your cardiovascular health and your vascular health benefits essentially your entire body. You know, like the brain, because the brain is relying on your vascular system to be powered. And so anything that affects your hearts, affects your brain, they call it clean fasting.

Barry Conrad
They specifically said they were doing a clean sixteen eight fast which is which is interesting right?

Melanie Avalon
Yeah, yeah, that's wild.

Barry Conrad
I don't think I've seen that in a study, like mentioned specifically, like a clean fast.

Melanie Avalon
That is so interesting. I wonder, honestly, you know, Jen Stevens, who used to be the the co-host on this show, like she really is the one who popularized the idea of the clean fast. I don't know if she originated it. She definitely, you know, is probably the reason it's out there is like a concept.

Shut up. Yeah. So, well, good find. Thank you for sharing.

Barry Conrad
Of course.

Melanie Avalon
So friends, support your heart with fasting and your body and your vascular system. And I guess with nitric, I always wanna say nitrous oxide.

Barry Conrad
Yes, I am, yeah, because of the wisdom teeth.

Melanie Avalon
Nitric oxide, I mean that probably benefits sexual health as well because I mean, it's not what a phiagra does. Yeah. Yeah, so everybody Everything in your body benefits the book I'm reading right now. I'm prepping is on dementia and cognitive decline and she was talking about Like the potential of Viagra for preventing cognitive decline for that same reason because of how it relates to nitric oxide Yeah, I think the studies are conflicting.

Yeah. Okay, basically there's interest surrounding it

Barry Conrad
That's wild. It's like, take fire, granule.

Melanie Avalon
benefit your brain.

Barry Conrad
Yeah, wow.

Melanie Avalon
Alrighty, well thank you for finding!

Barry Conrad
Of course.

Melanie Avalon
Shall we jump into some listener questions?

Barry Conrad
Let's do it. So we have the first question we have is from Stephanie and she asks, are you going to the biohacking conference? Where can I get a good vitamin C serum now that beauty counter is gone? And then sad face emoji.

What do you think about stem cells?

Melanie Avalon
All right, rapid fire from Stephanie. Rapid fire with longer answers.

So are you going to the biohacking conference? Well, by the time this airs, it was a while ago. But this is what I was saying in the beginning about I can share about my the past few weeks because I did go to the biohacking conference in Austin, that's Dave Asprey's conference. Next year, it's going to be called Beyond, like the Beyond conference. I think they're rebranding a little bit. But Barry, we were talking about this. We have to go. You have to come this year.

Barry Conrad
I really wanna.

Melanie Avalon
Oh, it's so amazing. Basically, it's just all these different brands and health and wellness are all in one room. So many podcast guests are there in person. I got to hang out with a lot of people that I've had on the shows. I also got to meet a lot of new brands. So I had a lot of like back-to-back meetings, just meeting all these different brands.

Like the new ones I met were I met a company called Sillient. I'm going to have them on my podcast. This was really interesting. They make a material that you weave into fabric and it actually takes your body's heat and turns it into infrared energy and puts it back into your body. So it's like clothing that helps your body's mitochondria and your energy. Actually, this is what was mind-blowing. They're in so many big brands. They're in like body armor, like the brand Body Armor and probably like 15 other pretty well-known brands, but they just haven't done any marketing around themselves. They've been in the shadows. So now they're creating their own product. It's a pillow. They actually gave me one. I haven't tried it yet, but I'm excited.

So I met them. That was cool. I met an electrolyte company where it's like electrolytes and hydrogen water tablet type thing. I met... Oh, this was fun. He was just on Dave Asprey's podcast actually. It's... Is it the first FDA-approved oral testosterone supplement? Maybe. I don't know if it's the first.

Barry Conrad
That's a game changer if that's the case because that's going to, wow, okay.

Melanie Avalon
if it's the first. It's definitely a big deal in the testosterone replacement world, although it's funny.

So I didn't realize that it's just for men, the FDA approval. So I had a meeting with them and I walked up and I was like, I am so passionate about this. We need more awareness about testosterone for women. And he was like, well, it's just for men right now. And I was like, okay, well, if you come on the show, can we talk about women a lot? So that was cool. But yeah, it was a really great experience. I got to go to the dinner, like they have some VIP dinners, I got to go to one and, you know, meet a lot of really cool people and they were, oh, Barry, how do you feel about EDM dances? Dances?

Barry Conrad
Yeah, it's with the right crew it's fun. I think it's fun. Did you go to one?

Melanie Avalon
So I've never been to one, so this was my first one and they had an EDM dance last night and apparently it was like some really big celebrity DJ, Steve Aoki, I think is his name.

Barry Conrad
Oh yeah, I know, Steve Okey, that's awesome.

Melanie Avalon
Yeah, so he was the DJ and and what was cool is because it's just the conference. So it wasn't like it wasn't that I mean, it was it was a good group, like it was a good crowd. So it was fun, but it wasn't like horrendously, you know, you can't breathe crowded situation.

You know, it was like in a ballroom at a at a hotel. So that was fun.

Barry Conrad
Did you really get your dance on or were you being shy or were you really getting into it?

Melanie Avalon
Oh no, I love dancing, yeah, yeah, I was really into it and then somebody came up and handed me, handed me and my sister these like chocolates, chocolates, slightly psychedelic chocolates, we did not take them but I saved them, so I might.

Barry Conrad
It's like mushrooms or something, what is it?

Melanie Avalon
Yeah. Yeah. So not that I have those anymore, but if I did, yep, we'll see. Stay tuned.

Barry Conrad
Stay tuned, dot dot dot.

Melanie Avalon
Yeah, I highly recommend the conference. That's the question.

That was Stephanie's question. Friends definitely go, oh, and if you go, please come up to me and say hi, because I would love to meet people in person. That's honestly one of my favorite things.

Barry Conrad
No, honestly, I saw some of your photos and it looked, it looked amazing. Like I looked, I cannot wait to go and daddy, your sister as well said, Barry, Barry, you have to come to the conference. It's really good.

I'm like, well, you've got to make it happen.

Melanie Avalon
Yeah, now it turned her into a biohacker. Now she's like, I think she, she was like on the fence. I don't know if she would identify as a biohacker, but she, this, this was the thing that like really sold it for her for, um, like, like, you know, liking, liking this world, I guess.

And we got to go see, she loves Jodha Spenza and we got to see Jodha Spenza. That was cool. See you next time. Bye.

Barry Conrad
So question about the dinner, the VIP dinner, you said, did you follow your fasting protocol? Did you eat? What kind of food did they have there?

Melanie Avalon
Oh, yeah. So I don't so that's my third time going to that dinner. And yeah, I didn't I didn't eat anything. And this is funny. So the table I was sitting at, I was sitting with a friend because it's like open seating and you can sit wherever. So I went and sat by one of my good friends. I met him through the company Stemmergem. I've had them on the show before. But in any case, at my table, so my friend was on one side of me and then on my other side was a bodyguard because somebody at the table was like that important that he had three bodyguards in the room. And I was telling my friend I and then and then Martin Luther King, sorry, Martin Luther King's like grandson. He was speaking at the conference, he came in the room and that was a lot of a high security situation. And that was right by me. And so I had a moment I was like, I'm either at this moment at like, the safest place or the least safe place. I'm not sure, probably both existing at the same time.

So yeah, it's a very high security room. It was it was really fun to answer your question with the food. The food was I think it was I gave mine away to everybody. I think it was steak. Yeah, I didn't eat any of it. Do you like you love steak? I know, but I don't I eat and then I go to bed. I you know, so if I so yeah, if I were to eat, I would just like fall asleep. It would take me out of my vibe.

Barry Conrad
Yeah, I get it.

Melanie Avalon
Yeah, it was fun. You must come!

Barry Conrad
I'm dead. It's happening.

Melanie Avalon
next year. And literally, we would get to hang out so much because it's if we stay in the hotel that it's in, you're just like there.

And so you like go to the stuff and then you hang out like I then afterwards, I went in the hotel lobby both nights until like really, really late hanging out with people. It's so fun.

Barry Conrad
It's happening, putting it out there.

Melanie Avalon
Yes, yes, yes.

Barry Conrad
Bookmark at this moment. Let's remember it.

Melanie Avalon
Yes. Okay. So those are my, my answer to that. And then where can I get a good vitamin C serum now that beauty counter has gone well, Stephanie, by the time this airs, assuming they don't push the launch beauty counter supposedly came back June 25th. So hopefully that happened because we're recording before that. So that's really exciting, but it's actually not called beauty counter anymore. It's called counter. I'm assuming my link will be counter.com slash Melanie Avalon. They haven't told us yet how the link is going to work. Either way, counter.com put me as your reference. That should get you, that'll get you on my, my list. And I send free things to people. So definitely, definitely check that out. And another alternative is crunchy. I talk about them a lot. I love them. They also have a vitamin C serum. So they're great for that. You can go to crunchy.com slash Melanie Avalon for that use the code advocate 10 to get 10% off your first order. And then also I am obsessed with oral glutathione or so oral wellness is vitamin C serum. So there's this called citrine. I use it every night. It's really, really powerful for that. Go to Melanie Avalon.com slash oral AURO. And then you can go to oral skincare, which is in the top left and definitely check out their citrine serum. It's super high potency. It's 25% vitamin C and glutathione. It's a complex of those. It's ridiculously powerful. I did it again. Sorry. It's ridiculously powerful. He's actually, I saw him. So Dr. Patel, he's the one that's his company and I love him. He has a book called the Glutathione Revolution. I'm actually going to bring him on this show on the intermittent fasting podcast. So stay tuned for that. Oh, he told me that he's trying to make an even a higher potency one that's like 50%, but he's trying to figure out how to do it with the bottles because it literally like breaks down the bottles. So he's workshopping that. Those are my ideas for vitamin C serum.

And I'm just assuming that that beauty count are now counter. Well, I'm sure they'll bring back their vitamin C serum because that was one of their most popular things. And then for her last... Oh, and by the way, really quickly, if you want to get the latest updates from me on all these things, you can go to melanieavilon.com slash cleanbeauty. And wait, wait, wait, Barry, are you going to have a... I forgot. I know we went through your lineup. Are you going to have a vitamin C serum in your lineup?

Barry Conrad
Not yet. We're going to have a vitamin A serum. Yep. But stay tuned.

Melanie Avalon
Like a retinol alternative? Awesome. Okay.

So and then the last question, what do you think about stem cells? Okay, that's a big question. So I mentioned stem region a second ago, they make a supplement that supports your body's endogenous release of your own stem cells. And so stem cells are super powerful. If you want to learn more about all the science of it, definitely check out I've done two episodes with Christian Japro. He's, he owns that stem region company. Stem region is actually the title sponsor of the biohacking conference. So when you go to the biohacking conference, there's like a million sponsors, but stem region is like everywhere because they're the main sponsor. They're incredible. I adore them. Shout out to Stephanie and Christian. I'll put links in the show notes to the two episodes that I've done with them, because you will get the deepest dive of deep dive into stem cells, how they work in the body, what they do. Essentially, for people who are not familiar, we naturally have inside of us these, they're like immortal cells, basically, they're cells that there's different types, but they can become anything. So most cells in our body are differentiated into what they are. So like a liver cell knows that it's a liver cell, and it's not going to become anything else. You know, and your bone cells are bone cells, they're just going to be bone cells. Stem cells, they're like this blank slate. And when your body needs repair, or it needs to, you know, fix things, things that happen with aging, stem cells get released from your bone marrow, and they go to that part of the body and then they can actually repair and become that thing. That's why they're so powerful for healing. And that's why people will do like stem cell treatments. And the idea with stem cell treatments is that you are bringing in these cells that can basically, you know, repair things. Christian is very much sold on the idea that they are, you know, literally the fountain of youth and that he thinks aging and death even is depletion of stem cells. Like he thinks that when we die, it's, you know, we basically capped out, we tapped out with our stem cells. He is more about, like I said, endogenous release, because basically you have this bank of stem cells that you can have, but our bodies don't always release them or use them. So his supplement that he has, and he has a whole story about how he found it, like it was this supplement that was having these profound effects with people's healing. And then he realized the connection to stem cells. And it's like this wild journey. But so that's one option is the endogenous release, I do really recommend stem regen. It's incredible.

Barry Conrad
It's a good name too, Stemmergen.

Melanie Avalon
Yeah, yeah, it really is. So for that, you can get 15% off, go to Melanie Avalon.com slash stem regen S T E M R E G E N and use the code Melanie Avalon to get 15% off.

And then as far as like stem cell treatments. So I think there's a lot of potential there. It's still this weird gray area. Like it's not, it's gotten better, I think, but there's been a lot of, like I think technically stem cell treatments are illegal in the US, but people get around them by doing like exosomes or, or doing stem cells, but like tweaking it and labeling it as exosomes. Like I've done a stem cell treatment in the US. And it was actual stem cells. It wasn't exosomes. I don't know how they got around that, but they did. A lot of people will travel out of the US and get treatment and it's way cheaper out of the US. Basically, my comments on it are, I think it has so much potential. I wish that there was more research on it and that the legality issue would get more easier and clearer in the US because it is, you know, difficult to, it's difficult to find, difficult to go with somebody who trusts with all the issues surrounding it. And I think there's a lot of potential, but I just wish there was more studies.

Oh, that was a lot. Do you have thoughts Barry on vitamin C serums, biocompare and stem cells, all the things.

Barry Conrad
I feel like you answered that beautifully, Melanie. I don't think there's anything that I could add that could be any better than that. That was great.

Melanie Avalon
Have you done anything with stem cells before or thought about it?

Barry Conrad
I actually haven't I was gonna ask you the what what inspired you to to get stem cell treatment like why was it a health issue going at the time and did you feel any different after that process.

Melanie Avalon
Yeah. So it was an opportunity that was presented to me. It was a practice that wanted to collaborate. So they were starting to do stem cell treatments at their clinic and they basically offered to to do it for me at like the cost of basically they just charged me for the stem cells. They didn't upcharge anything as far as like I got it for a really good price is the point.

And they also used me for training. So like everybody was watching when they did it. The reason I was really interested in doing it was I had this injury in my knee that happened. I know when it happened. It happened actually when I went to D.C. for beauty counter in was that 2021? And my knee just always had this. It was really, really bad in the beginning, like the pain and then wasn't really going away. And it's hard to know. Basically, I don't have that issue now. It's gone. The issue is completely gone.

What's hard to know is they say it takes like six months from the injection until you'll feel better. So it's hard to know. It's hard to know like, Oh, well, would I have been better anyways after six months? You know what I'm saying? I think it would be more telling if I had done it on an injury. I don't have one of these, but if I'd had an injury that I'd had for like a decade, you know, or like at least like longer where I was like certain it wasn't going away. And then yeah.

Barry Conrad
Otherwise, it's like, is this placebo or is this the actual, yeah, I get what you're saying.

Melanie Avalon
Did I just, did my body heal on its own anyways? Um, but I do know, I mean, it is completely gone now. So I just know the injection was way worse than I thought it was going to be.

Barry Conrad
Like, what do you mean? Like, just like a big needle? Like, what's, what's

Melanie Avalon
Yeah, yeah, the needle was massive massive like the biggest needle I've ever seen and then He they freeze the skin so he froze it and he's like you're not gonna really feel it cuz it's gonna be frozen Oh, and it was so painful And it took so long like like to like push it in and I was just like in my head I was like, oh, this is not this does not feel good. This is not feel good

Barry Conrad
Did they give you anything to deal, handle that pain or not?

Melanie Avalon
No, no, in retrospect, I probably would have doped myself up before, but we survived. So it probably, it probably helped that so many people were watching because, you know, then you're in like performance mode and like fight or flight, you know?

Barry Conrad
Yeah, exactly. It was really interesting what you said about the theory on stem cells being, you know, us dying or even aging as lack of stem cells or stem cells being depleted, that I've never heard before.

That's interesting.

Melanie Avalon
It's really interesting. I mean, that's just his theory, and he's very open that that's just a theory for him, but that's what he thinks it is. He thinks death is like stem cell exhaustion.

Barry Conrad
So basically, you know, in some reality, let's go to like this, the stem cell vending machine, and just buy like a new cartridge and just like you measure like battery levels going up and you rejuvenate it again. Like I'm just, you know, some futuristic universe. That's maybe a thing.

Melanie Avalon
Yeah, well, what's really interesting is I mentioned stem cells being immortal and I should clarify, I don't mean that they're immortal, but what I mean is basically, at any given point in your body, you have these cells that are young cells. Like the stem cells are, even if you're old and you even if you're like, you know, in your 70s or 80s, and you release endogenous stem cells, those stem cells are young, you know, and then they can become anything.

And Dr. Walter Longo talks about this as well in his book. He talks, maybe it was David Sinclair, one of them, maybe both of them. People talk about as well, how it seems like in theory, our bodies would hold the key to immortality because we can make embryos that are like a, you know, a brand new human. So it's like if we can do that, in theory, it's possible for cells to become, you know, completely new and young again.

Barry Conrad
Very interesting. So.

Melanie Avalon
Yep.

Barry Conrad
And I know that you, and I know that Melanie, listeners probably already know this as well, your thoughts on longevity as well, on living, you wanted to live, you know, live a long, live a long life. Live forever.

Melanie Avalon
I'm I'm all about it. So

Barry Conrad
Only if you look the same, right? Not like not.

Melanie Avalon
Right. Yeah, I'd like to like tap. I'd like to, yeah, plateau at a certain or age backwards, if required. It's funny, whenever I hear stem cells, because I was raised in a very Christian church and it was during the time and I went to a Christian private school and it was during the time that there was all the stem cell controversy was when I was in like high school, I think. I remember hearing like stem cells and like thinking, oh, those are really bad because because there was a lot of controversy around embryonic stem cells.

But what I want to clarify now is it's not, well, a few things. One, the embryonic stem cells they were using presumably were stem cells that would have been thrown away anyways, but that's a whole, that's a whole another topic. Now it's not, it's typically not embryonic stem cells that are used. It's typically, it could come from a lot of different places, but it came from like the placenta rather than the embryo. There's other places it can come from. I should be more knowledgeable on this, but it's not typically embryonic stem cells that are being used today is my point. That's super fascinating, Mel. I know. I'll be really curious. I'll be curious to see what happens in the future with all of this. So should we have our proverbial breaking of our fast?

Barry Conrad
We actually should and you know what I think today more than any of the show in recent times I feel like super ready so like this is going to be awesome.

Melanie Avalon
because you're fasted, right? Well, actually, wait, you're normally fasted, right? Or normally you're fasted, but it hasn't been as long. Yeah, exactly.

Yeah, you're feeling it. Okay, yeah, welcome to my world. Again, how many times can I say that? I'm picking this one, right? Yes, so I have a surprise for you. It's not a Disney restaurant. It's not? No, and actually, I was actually gonna do another non-Disney one, but then today, a listener, shout out to Christina, she suggested this restaurant.

Barry Conrad
Oh wow. Shout out Christina.

Melanie Avalon
I know. So I'm going to tell it to you, but first I want to read her message about it. Can I read her messages?

Barry Conrad
Yeah, let's hear it.

Melanie Avalon
So this is where she lives, I guess. So she said, we're going out to dinner Saturday evening to our favorite place.

And I was just playing the menu game and realized that this is one for Mel and Barry Conrad. She said, and then I asked her, why does she like it? And she said, the quality of the food is off the hook. The diversity of the dishes, the varietal of meats. There's always something so different and the vibe is fun. When you read the menu, you can see that they've got a great sense of humor, very tongue in cheek. Barry will flip for the oyster caviar service menu and all the spirits. I think you will be very happy with the wine list. I am a big fan of the cocktails. They're also on the SOS app, the Seed Oil Safe app. And then she says, last time we went, there was a rack of lamb that was amazing, but I didn't see it this time. They changed it up frequently. I can't wait to see what you guys order.

Barry Conrad
Wow, that sounds delicious, Christine. Thanks so much for the tip.

Melanie Avalon
Yeah, and so when I looked at the menu, it's really cool. They're into like all sustainable and local sourcing and they have wine awards. So let me send you the link.

Barry Conrad
Hey, let's, I can't wait to check it out now. That lamb sounded legit. I love lamb so much.

Melanie Avalon
So it's called Perron's Restaurant and Bar, changing lives one dish at a time. And they say, let me see where it is. So it is in Polly's Island, South Carolina. They say on their main page. So they say that their menu is always a work in progress, that they always evolve and change it with the goal of creating one of the area's most unique, exciting and delicious food experiences.

They consider it world cuisine with a Mediterranean focus. They're all about local and organically sourced when available. Their proteins are growth hormone and antibiotic free. They use local poultry farms, ranchers, fishermen, crabbers, clamors and shrimpers, sustainably farmed salmon. And let's see, they're very serious about their cocktails, wines and beers. They have a wine spectator award-winning wine list and they have a core event so that you can, you know, try vintage and price your wines. So shall we look?

Barry Conrad
Let's have a look. I'm going to click on the, should I click on the menu here? Appetizers.

Melanie Avalon
Yes. Okay. So appetizers. Wait. Hey, so app. Okay, wait. So we have options. So there's appetizers, entrees, chop house, caviar service oysters. Should we look first at the caviar service oysters?

Barry Conrad
Yeah, I reckon that'll be before, you know, like before the substantial entrees. Okay, perfect.

Melanie Avalon
So, well, we know, we know how I feel about oysters at the moment, at the moment, but I like caviar. So what would you get from this?

Barry Conrad
Okay. And here's that word again, shucked. So I'm going to get, there's oyster shooters, listen, so fresh shucked oyster of the day. I'm not going to, there's the Japanese Bloody Mary. I don't love Bloody Mary drinks in general, so I don't think I'm going to like that one.

There's the caviar oyster shooter, which is, oh, there's the caviar, sorry, which is American hackleback Russian standard platinum vodka, creme fraiche, seaved egg, and chives. I reckon I'm going to do that. And then I'm also going to do, uh, there's so many options here. I'm, ah, what I'm going to do the, the gold service Royal Beluga.

Melanie Avalon
I knew you were going to get that. How'd you know? Because you like the... We talked about the Volugas, the fancy pants one, right?

Barry Conrad
Yep and it's got like warm blini, seed oil-free sea salt, kettled potato chips, creme fraiche, seed farm egg chives, chilled caviar. So delicious. What about you Mel?

Melanie Avalon
I love that they put seed oil free on the menu.

Barry Conrad
Yeah, that's specific. It's good.

Melanie Avalon
So I think I like the, I want to try the smoked trout row and chips, but not the chips, but it can be on the side.

Barry Conrad
So can I have those? Yeah.

Melanie Avalon
you can so like plain do they have just wait caviar eggs so they don't have just plain caviar right oh oh yeah they do yeah they do the silver service oh right oh well you got the royal beluga caviar so i'll i'll like taste that if you'll let me taste it and then and then i'll take wait you did get some oysters right or did you not

Barry Conrad
I got some oysters shooted. I got the...

Melanie Avalon
Oh, right, wait.

Barry Conrad
Oh, I didn't get oysters, I said, I didn't get oysters, no, no, no, no, no. Oysters in the half shell, I'll do that for sure, fresh oysters.

Melanie Avalon
Okay, well, I will maybe taste one of those.

Barry Conrad
It's gonna happen now. It's closer. It's more of a chance now that I live here because I you know I feel like I'm creeping in it's coming in and it's gonna happen

Melanie Avalon
Yeah. I'll taste it for you. I'll take one for the team. That's why I'm here.

Barry Conrad
Should we go to the appetizer slash entrees?

Melanie Avalon
Yes. Or wait, yes, yes, yes.

And there's also the steakhouse or the chop house option. Oh, it's all on here as well. Oh, it's on here. Oh, and it's the chop house. Oh, this is the full menu it looks like. Okay, so starters. Is there a starter that you like?

Barry Conrad
Yeah, the starters, you know what, I'm definitely going to do, have to do a burrata. I love burrata cheese so much. I'm doing that.

I'm going to have the, from what I can see here, there's dry aged salmon roulettes. That sounds really good. It's a spreadable dip, poached coho salmon, dry aged in house, smoked salmon per nod, salt and shallots, lemon zest, butter and crème fraiche. So the toasted baguettes, that sounds really good. And then last but not least, I have to get the mussels, Bangkok mussels. You, Mel, you haven't tried mussels, right? Have you? You said this. It could be a lucky day, oysters and mussels.

Melanie Avalon
if I can, like, get to, actually, I might, seeing what's on the muscles, I might actually just, I might try them in the, the sauce. Maybe, maybe, we'll see.

I think I would get maybe the Wagyu steak tartare, plain, everything on the side, if possible. Oh, it's from Georgia.

Represent. And yes, yeah, yep. And I don't have to specify how to order because tartare is rare or raw, which we love. I love

Barry Conrad
Blue Raw. Also Mel, I just realized I could have gone to this place because I went to Charleston a couple years ago. If we had been doing the show then I could have ducked in.

Melanie Avalon
Oh man, next time.

Barry Conrad
Okay, well, should we go down to the soup and salad? You into the soup and salad, are you going to skip that?

Melanie Avalon
I'm gonna skip. Feel free to get something though, if you like.

Barry Conrad
You know what, I'm just going to do the crab soup because I do love a good seafood chowder type situation. So North Carolina, lump blue crab.

You know how I feel about trying things from the actual area. So doing that crab soup.

Melanie Avalon
And I love what they say, I mean, you didn't get a salad, but all of their dressings are made in house from scratch with no processed or refined oils. So there's no trans fats. And they use non GMO, expeller pressed avocado oil and cold pressed extra virgin olive oil. That's super cool. That's first.

Barry Conrad
It's good.

Melanie Avalon
It's for all the, because there's all the concerns about the seed oils. Okay, for Andre, what are you going to get? This looks, there's so many things I want.

Barry Conrad
I know. Oh man. Uh, what am I going to get? Okay.

Here we go. I feel like I'm going to do the, the USDA prime ribeye 16 ounce. It's a prime chop. I'm going to get that medium rare. And then I'm also going to get with that side of mushrooms and onions. Love mushrooms so much. Bacon, mac and cheese and some roasted butternut squash.

Melanie Avalon
Okay, I'm gonna get definitely the elk tenderloin for sure, grass-fed pasture raise, cooked sous vide to medium rare. Oh, specified, I wonder if I can get it rare. I'm gonna ask if I can get it rare. I'll get everything on the side.

It's a lingonberry and pork sauce. If you wanna try it, otherwise I'll get it without it. I'll try it. Okay, on the side, lingonberry and pork sauce, organic grain, medley and grilled vegetable. And then I also want a fish. So depending on what the fresh catch of the day, okay, so if the fresh catch is trout, then I will get that.

Otherwise, interesting that it's a dry aged salmon. That's interesting. Well, I think it depends. Yeah, either the fresh catch, depending on what it is, or then I might switch it up and get duck, which is jurgle wicks. I don't know what that is. Duck breast, pan seared, two potato mash and grilled vegetable, blackberry pork demigle.

Barry Conrad
That sounds pretty good. The Blackberry report doing glaze sounds interesting.

Melanie Avalon
Interesting, too, that the fish is, that they already say how it's prepared, you know, that they don't adjust it based on what the fish is, but it's with black forbidden rice with a sauce of saffron, preserved lemon, shallots, white wine, shrimp stock, and cream. So it must always be a fish that goes well with that, you know.

Barry Conrad
Yeah, the combination. Yeah. I actually drink many. We need to definitely check out their wireless cocktails.

Melanie Avalon
Oh yes, and the dessert.

Barry Conrad
Happy ending slash liquid dessert slash dessert. Let's do that first.

Melanie Avalon
Yes, I like the quote says seize the moment. Remember all those women on the Titanic who waved off the dessert cart. Alcohol and dessert because adulting is hard.

Barry Conrad
I like that. I like these quotes. Yeah.

Melanie Avalon
Me too.

Barry Conrad
Is anyone catching? Is anything anyone? Is anything catching your eye on this dessert menu, Mel, that you can see?

Melanie Avalon
Desserts, I will probably get another entree, some fish or something. If I were to order a dessert in my, you know, dream world where I eat desserts. Oh, wait, these are drinks. Where's the actual?

Barry Conrad
If you go all the way right down to the bottom of the page.

Melanie Avalon
Probably, I would just get the house made ice cream.

Barry Conrad
Yeah? Mm-hmm. That sounds pretty good.

Melanie Avalon
How about you?

Barry Conrad
I'm gonna get a couple of things, see if you can guess.

Melanie Avalon
I think you want the warm chocolate layer cake. Yep, you got it. And you're going to add a scoop of ice cream. Yep, you got it. And then you want, do you want creme brulee?

Barry Conrad
Yes. Well, I was going to say, how'd you know? It's like, Barry, we've done this.

I'm a creature of heaven when it comes to ordering food. I think Melanie knows that. I think you all listening know that as well.

Melanie Avalon
Was there another one that you wanted or those two?

Barry Conrad
I think those two because I had, I've added a couple of things in the savory. So I reckon that's pretty good.

And then definitely to find a, they said they were famous for their cocktails, right? So yeah.

Melanie Avalon
and I'm gonna look for the wine list while you're looking at the cocktails. See, we work well as a team.

Barry Conrad
See? I already know what I want from the cocktails.

Melanie Avalon
Do you see a cocktail that you like?

Barry Conrad
I do. So I am eyeing the chili margarita. Surprise, surprise. Gonna do that.

And then also I'm going to try the casa fresca, which is like fresh muddled mint, lime and cucumber, agave, splash of grapefruit, and club soda.

Melanie Avalon
I, okay, this wine list is really low.

Barry Conrad
And if you happen to spot a decent looking Pinot Grigio mill, I definitely will get that for like the table. AKA probably, I don't know if you'd have it, but I'd be sipping in that as well.

Melanie Avalon
They have a Pinot Grigio from Italy and they have one from Oregon.

Barry Conrad
I'd probably go the idly one.

Melanie Avalon
And then for me, I'd have to look up and find if these are organic or not, but I would probably get something French. They have a few bougoulets. I love bougoulets.

So I probably, they have four bougoulets from France. So I think I would look up those and see which one is organic. And because they have a, see what it says about the tasting. I'm guessing that, because they said earlier that they had the Coravinne, so I wonder if they, if you can like taste the ones by the bottle, that would be super cool if you can. I'm not sure if you can. So something French, I'm thinking, oh, or am I get, they have two burgundies. So maybe one of those.

Barry Conrad
Either way, they weren't lying when they said they had a long list. It looks pretty good from what you're saying.

Melanie Avalon
Oh, they have four burgundy pinot noirs. Okay. So yes, I basically would look through the four burgundy pinot noirs and the four Bourgeois, and I probably would do, I would do one of those to be determined. So thank you, Christina, for the recommendation.

Thanks for the, thanks so much, Christina. We're going to have to check it out when we're there sometime.

Barry Conrad
The restaurant tour we were doing was going to be like a spin-off like it's going to be.

Melanie Avalon
That would be so fun. We could go to every restaurant that we've had that we've like mentioned.

Barry Conrad
You'll like whittle it down like you look this massive tall and then people get to see actually what you know how we eat really for real

Melanie Avalon
really fun. That'd be a lot of travel though. I don't know if I got to like, I got to prepare myself mentally for that. That's yeah, we'll think about that.

Barry Conrad
We may need to do like maybe like a road trip version, like just in America or something, or just Europe, or just pick a country and then...

Melanie Avalon
Maybe once I have a private jet and we can just like easily go there. I don't know if I can do all that trouble.

Barry Conrad
Barry's doing it, I'll just sleep. You can video me in. So funny, sounds good.

Melanie Avalon
All right. Well, this was super fun. Listeners, we hope you enjoyed today's show.

These show notes will be at ifodcast.com slash episode 436. Those show notes will have a full transcript as well as links to everything that we talked about. So definitely check that out. And you can get all the stuff that we like at ifodcast.com slash stuff we like. You can follow us on Instagram. We are ifodcast. I am Melanie Avalon, Barry as Barry underscore Conrad. And I think that's all the things. Anything from you, Barry, before we go?

Barry Conrad
No, thank you so much for tuning in everyone and we will chat to you next time. Talk to you soon, Mel.

Melanie Avalon
talk to you next week. Bye.

Thank you so much for listening to the Intermittent Fasting podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing a review on iTunes.

We couldn't do this without our amazing team. Editing by podcast doctors, show notes and artwork by Brianna Joyner and original theme composed by Leland Cox and recomposed by Steve Saunders.

See you next week! you



 

 

Dec 08

Episode 399: Special Guest Megan Ramos, Therapeutic Fasting for Women, Holiday Eating Tips, GLP-1 Medications, PCOS and Insulin Resistance, Pregnancy and Fasting, Longer Fasting Protocols, and More!

Intermittent Fasting

Welcome to Episode 399 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine, and Vanessa Spina, author of Keto Essentials: 150 Ketogenic Recipes to Revitalize, Heal, and Shed Weight.


SHOW NOTES

SPECIAL GUEST:

Megan Ramos is a Canadian clinical educator and expert on therapeutic fasting and low-carbohydrate diets, having guided more than 14,000 people worldwide. She is the co-author of the New York Times Bestseller Life in the Fasting Lane and The Essential Guide to Intermittent Fasting for Women.

Website | IG (Fasting Method) |  IG (Megan Ramos)


SPONSORS & DISCOUNTS:

SEED: Seed's DS-01 Daily Synbiotic is a 2-in-1 prebiotic and probiotic formulated to support gut health, skin health, and overall well-being. With clinically and scientifically studied strains, Seed's Daily Synbiotic promotes digestive health, boosts immune function, and enhances your body's nutrient absorption. Start your journey to a healthier you with Seed's innovative and effective synbiotic formula. Get 25% off your first month of DS-01® with code 25IFPODCAST at seed.com/ifpodcast.


BUTCHERBOX: Grass-fed beef, organic chicken, heritage pork, wild-caught seafood, nutrient-rich, raised sustainably the way nature intended, and shipped straight to your door! For a limited time, go to butcherbox.com/ifpodcast and get 2 lbs of grass-fed and finished ground beef in every box for life! Plus, get $20 off your first order!


STUFF WE LIKE: 

Visit ifpodcast.com/stuffwelike for all the stuff we like!


OTHER LINKS:

Vanessa's Tone Device: The Tone Device Breath Ketone Analyzer

Melanie's podcast: The Melanie Avalon Biohacking Podcast

Vanessa's podcast: The Optimal Protein Podcast

More on Melanie: MelanieAvalon.com 

More on Vanessa: ketogenicgirl.com


If you enjoyed this episode, please consider leaving us a review in Apple Podcasts!


Original theme composed by Leland Cox, and recomposed by Steve Saunders.


Our content does not constitute an attempt to practice medicine and does not establish a doctor-patient relationship. Please consult a qualified healthcare provider for medical advice and answers to personal health questions.

TRANSCRIPT

(Note: This is generated by AI with 98% accuracy. However, any errors may cause unintended changes in meaning.) 


Melanie Avalon

Welcome to Episode 399 of the Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat, with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker, author of What, When, Wine, and creator of the supplement line, AvalonX.  And I'm here with my co-host, Vanessa Spina, sports nutrition specialist, author of Keto Essentials, and creator of the Tone Breath Ketone Analyzer and Tone Luxe Red Light Therapy Panels. For more on us, check out ifpodcast.com, melanieavalon.com, and ketogenicgirl.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment.  To be featured on the show, email us your questions to questions at ifpodcast.com. We would love to hear from you. So pour yourself a mug of black coffee, a cup of tea, or even a glass of wine if it's that time, and get ready for the Intermittent Fasting Podcast. Hi, friends. Welcome back to the show. I am so incredibly excited about the conversation I am about to have.  It is with a very, very popular guest. So I've had today's guest on the show before. And I often ask for questions in my Facebook group for guests. And whenever I even remotely mention this beautiful person, I'm here with Megan Ramos, I get inundated with optimism and excitement and enthusiasm because people love what you're doing, Megan.  And so many people say that, you know, they're the reason that they found fasting and, you know, change their lives and things like that. So I get so much gratitude. And then I also get so many questions for you. And I had you on the show before.  And that was before you had released or yeah, I'm pretty sure that was before you had released your newest book, which is The Essential Guide to Intermittent Fasting for Women, Balance Your Hormones to Lose Weight, Lower Stress and Optimize Health. That book honestly is absolutely incredible when it comes to just being a I mean, it's in the title, An Essential Guide to Intermittent Fasting.  And what I also loved, there's an endorsement on it by Cynthia Thurlow, who my audience will be very, very familiar with since she was a former co host as well. Megan has a lot of her background working with Dr. Jason Fung, who is a legend in the fasting world. And she wrote the New York Times bestseller book with him life in the fasting lane. So Megan, thank you so much in advance for being here.  And also I know it's been a while, but last time we had you on that was pre pregnancy and baby and this is post pregnancy and baby. So congrats on that. How old now is your who's it a boy or girl?

Megan Ramos

I have a son. His name is Marcus, and he's just about 13 months old. So it's pretty wild. I don't think I've slept since I was last on your podcast. It's all been kind of a blur. Pregnancy was a bit rough. And then this last year has been crazy.  I appreciate your very kind intro though, Melanie, I feel like for the last year, I've just been known as my son's cow and the lady who doesn't sleep at the end of the street. So it's good to hear that makes me feel a little bit more like myself, and like all these long hours are worthwhile and hopefully we're helping a lot of people out there.

Melanie Avalon

No, I literally have so much gratitude. And I talk about this on the show a lot. I personally don't anticipate having kids. I just don't really see it as part of my life. And so I am, I am so I don't know how you guys do it. And I am so grateful to moms like you for, you know, taking one for the team. They're like, I could not, I could not, not do it.  And I'm going to ask a listener question right off the bat because something relates to this. Teresa, she said she wanted to know, she said, I know pregnant women aren't supposed to fast. So I'm curious what Megan's eating patterns were when she was pregnant. What times and what types of food did she have? So yeah, I'm curious about that as well. Did you get create?  Well, first of all, did you get weird cravings during pregnancy?

Megan Ramos

I did not have any weird cravings at all during pregnancy. I didn't really change my diet. The weird thing about my pregnancy was that I ended up having two placentas. And I didn't know this. And it kind of explained why my pregnancy was so awful at the very end. But I had these two placentas, the one my son's main placenta, and then I had this accessory placenta.  And they caught it at the last minute, which is great, because we both got to live. And it was actually a pretty serious condition called type two of azaprivia. It got caught by a real fluke. So I mean, all the stars align there to keep us alive and healthy. But I was super sick.  And I had all these dreams and plans of eating and how I was going to structure everything and make everything as nutrient dense as humanly possible going into pregnancy. And I was barely alive for the eight months that I was pregnant before I was born. He ended up having to come early because of the placenta issue. And I was amazed that I like he was growing and that I didn't end up in the hospital.  But I'll say like during my pregnancy, whatever food I could tolerate, I just like ate and ate and ate. And that changed as my symptoms change. But I stuck very true to like a real whole food kind of principle, I guess, sort of paleo. But I did do things like drinking raw goat milk from a farmer that I knew was very comfortable with. And you know, eating a two sheep yogurt.  So I did have some, you know, type of dairy sources as well. But yeah, just kind of stuck to my regular I really prioritize protein. Fortunately, I could eat beef, but I couldn't like tolerate like a New York strip for some reason. But I could tolerate fillets like wrapped in bacon. So I think like for like two months, like that's all I ate for like dinner.  And my vegetables, I just try to cycle through and I did eat some carbs, you know, I usually would have some berries at lunchtime. And then I would have like some sweet potato or some root vegetable at dinner time as well. And you know, I did gain 26 pounds by the time he was born. And he was born at five pounds, eight ounces a month early.  So you know, it was enough, at least to keep him going and thriving. But all of my plans for like a real, you know, like ultra nutrient dense pregnancy kind of went out the window. And I just had to go with what my body let me eat. But I know I didn't have fast food, I didn't have junk food once, you know, I we ate at home, pretty much we did take a trip early on in our pregnancy to lanai.  And we were fortunate they had like things like grass said beef and avocados actually really helped with my early nausea. And they're high in B6, which I kind of knew but then really became aware of once I was pregnant. So I pretty much ate grass said beef and avocados the entire time we were in lanai. And I could eat eggs, eggs didn't seem to bother me.  So just yeah, just trying to get in when I could tolerate within my own dietary principles. But I didn't shift anything. Prior to pregnancy, I you know, I did eat some carbs, I ate berries, I did eat root vegetables and smaller portions.

Megan Ramos

They're not things I ate when I was struggling with insulin resistance. But they were things that I strategically added into my diet afterwards. And I continued to consume those throughout pregnancy to tolerance.

Melanie Avalon

Wow. Okay. So many questions. Well, I love how you were saying that you had these dreams of eating nutrient rich and then it sounds like what you ate was really nutrient rich to me. Sounds like you did pretty good.

Megan Ramos

I think I thought I was going to eat like liver like a few times a week.

Melanie Avalon

the organ meats and all the things. Okay, I hear you. Did you change your eating windows?

Megan Ramos

Yeah, I did. And I actually banked embryos, I went into mommyhood, actually a little bit late in life. So a lot of your listeners know, and for those of you who don't, I was diagnosed with PCOS when I was 14. I was actually kind of amnoxiously skinny preteen. And I had PCOS and it was kind of weird, like I didn't have acne, I actually had regular periods.  But I started cycling, you know, just before my 10th birthday, like really kind of abnormal PCOS stuff. You know, I have been able to correct that later on in life, but it didn't undo some of the damage that happened earlier. So when a woman has PCOS, they burn through a lot of follicles early on in life. And we're only born with so many eggs.  Like we don't have an infinite supply of eggs that we can generate over time and genetics, you know, plays a big role in dictating how many eggs we have at the start. And then things like PCOS, you know, plays a role kind of in the life, like the longevity, like how often, you know, or how long we have those eggs for. If you have PCOS, she'll burn through a lot earlier on.  So when I was older, and we decided it was time to start a family, I wasn't that old. I mean, I just turned 40 and my sons one, I had low ovarian reserves because of my past. So I we decided to bank embryos, because we would like to have a second kid. So I did the whole IVF thing. I was very fortunate, though, because of my lifestyle, I had really high quality eggs.  So even though I didn't have like a ton, because of my history of PCOS, I had some really good raw materials to work with. And that gave us an amazing baby boy very easily from IVF. So we were very fortunate in that respect.

Melanie Avalon

Well, I didn't know that about PCOS and the eggs and IVF. That's amazing. And the high quality eggs with the fasting, how did you change it?

Megan Ramos

Yeah, my mommy brain here. I'm so sorry. Yeah, so pretty much like my maintenance plan, because you know, I've, I've improved a lot of health markers, like reversing type two diabetes, and my PCOS and fatty liver, and I lost a lot of weight and kept it off for a long time. And pretty much since I hit my goals, I've really like eaten two meals a day.  And then as my schedules just kind of dictated it, I've done fasting. So like, prior to pregnancy, I had a class every Wednesday evening. So I just ended up doing 24s, a 24 hour fast every Wednesday, I had a long flight, which I often did, you know, I would cycle in some even longer fasts.  And then I would strategically plan a few extended fasts a year just for longevity, health improved health span reasons. But you know, going into pregnancy, sorry, going into my IVF journey is where I got lost my tangent there. I started doing 14 hour window only, and having three smaller meals throughout the day.  And I'll say like with all my symptoms, it was the only way I was able to get in I think enough food at the end of the day to keep a healthy pregnancy without having to go into the hospital or something like TPO and just I wouldn't want that for my son's development. And I could avoid it.  So having the three smaller meals throughout the day did help quell a lot of my side effects and enable me to get in a good I guess a good low love like low diet of nutrient density throughout the day enough to have an optimal healthy baby at the end.

Melanie Avalon

So you were still, because I think people get really nervous with pregnancy and everything, and we get lots of questions about breastfeeding as well, but you were still eating in a slightly restricted window.

Megan Ramos

Yeah, you know, I still got in 14 hours a day. It was pretty easy. I never snacked unless like, I really felt kind of like I needed to. During pregnancy, my whole thing was like, if I if I felt hungry, like I wasn't going to say, Okay, you know, have some sparkling water and just try to suck it up. Pregnancy is a time for growth. And it's not a time for for fasting.  So I just made sure to listen to my cues. I think I was so fortunate. By the time I did get pregnant, I'm like incredibly in tuned to my body and its needs. I know when I'm thirsty versus hungry, and vice versa. So I never really withheld but I found like I was able to maintain, you know, three smaller meals a day, and sort of a 14 hour window pretty easily, you know, throughout my journey.

Melanie Avalon

Okay, awesome. Yeah, so I have more questions about the windows and fasting and everything, but while we were talking about PCOS, I did have a good question about that. It was from Leah, and she wanted to know if someone is a type 2 diabetic and has PCOS, did one lead to another?  Are they both just caused by high insulin or is there some other component that influences which way this insulin resistance manifests? Would you treat the two the same with diet and fasting or should one thing be taken into consideration with PCOS?

Megan Ramos

Yeah, lots of really good questions. PCOS is essentially like diabetes of the ovaries. So PCOS and type 2 diabetes are both caused by insulin resistance. Genetics sort of can play a role too as to what of these expressions of insulin resistance, like which of these diseases you're likely to develop to over time, although I think I was actually like the first person in my family to have PCOS.  There's a whole bunch of them, like I had fatty liver, PCOS, and then eventually type 2 diabetes. As the insulin resistance becomes more severe, the more expressions and diseases related to it, you're going to accumulate over time.  And unfortunately, due to all of the dietary crazy changes that happened in the late 70s, a lot of women in my age group and younger women are struggling with multiple metabolic diseases as they've gotten older. So it's really common to see PCOS and type 2 diabetes come hand in hand. I had actually a lot of women that come to us with PCOS that was established when they were younger.  When we do look at their diabetes markers, sure, they're not classically abnormal by like tradition Western medical standards, but by functional integrative standards, like they're not good. And the person is usually on the cusp of being diagnosed with type 2 diabetes as well.  You know, it's sort of a bit controversial, I think, and even in the fasting space, how we treat this, a lot of my colleagues outside of the fasting method and Jason, who work with women with PCOS, they always kind of like try to treat the PCOS and the sex hormones and get those balance first, and then, you know, sort of tackle the diabetes.  What Jason and I have always done at the fasting method is treat the insulin first, we end up sort of, you know, knocking down two birds with one stone. But really that the insulin resistance is what's causing the sex hormone issues that's leading to the PCOS. And it's just it's a perpetual cycle.  And, you know, sometimes I think just treating the hormones, especially in severe cases where someone also has something like type 2 diabetes, we know the insulin resistance is on really bad. So really trying to target the sex hormones is just kind of, it's frustrating, it's a long lengthy process. And when there's type 2 diabetes parallel, it doesn't always work.  So in if we have a woman, say a 27 year old woman came to me, she's a newly diagnosed type 2 diabetes, she's known since her teen years, she had PCOS, she's looking, you know, to maybe want to have the possibility of conceiving down the road, she just wants it to be an option. So she does want to tackle the PCOS.  And she's struggling with the symptoms of PCOS, like acne, facial hair, but we don't want those symptoms if you know, we can avoid it. So what do we do? And I would treat them like a diabetic first and foremost, in the sense like, you know, we're treating the insulin resistance. And that's kind of what we say.  But I mean, the if you you just rephrase the PCOS is that's diabetes of the ovaries, we're treating the insulin resistance, the diabetes of everything kind of first.

Megan Ramos

And then once we have regained insulin sensitivity in the body, then we really focus on trying to optimize the sex hormones, like, you know, where they're still in balances, where they're still, you know, low levels of progesterone, or the issues with androgens, like, how do we optimize those down the road? And we found it to be, you know, very, very effective.  You know, fortunately, we've helped a lot of women, you know, with PCOS, who wanted to be moms become moms, which has been really great, you know, they told me at 14 that I would probably never be a mom. And here I was, you know, like, I, I got pregnant, first embryo transfer, no issues right off the bat, you know, and, and had a lot of luck.  And there's just there's so many opportunities for these these women. So it's been grateful to be part of these journeys. But even if motherhood is not something of interest, like we still want to treat the PCOS because it is like type two diabetes, but of the ovaries.  So we want to fix that get rid of the potential side effects that someone might be experiencing as well, and just improve their overall health outcomes. And we treat everybody like a diabetic in terms of fasting protocols at the start.

Melanie Avalon

That's incredible. And so when you say doing that first and then potentially treating the sex hormone issues, is that with like bioidentical hormones or HRT?

Megan Ramos

We don't do that at the FASTA method, but if there's things that we can do, we would recommend it in certain cases if needed. Or if there's just things that we can do nutritionally to boost things like progesterone levels.  You know, when someone's a type two diabetic and it's causing these other issues, and there's like PCOS and insulin resistance is causing the imbalances, we will, for example, you know, in a cycling woman, fast them fairly aggressively throughout the duration of their cycle. But once we've tackled the insulin resistance, then we want to optimize the hormones in each part of the cycle.  So once we've sort of tackled the insulin resistance, something that we would do to help optimize the hormones then is sort of more fasting. And the beginning of the cycle, less fasting in the second half of the cycle, more structured carbohydrate intake in the second half of the cycle to support progesterone production, for example.  So there's hacks that we would do nutritionally to see if we can optimize things first. We're fortunate, like for certain age demographics, we've had a lot of great benefits doing that. Generally, as women get older, like taking bioidentical hormones does have a lot of longevity benefits.  I chose my own will and accord as a 38, 39 year old woman pregnant to take bioidentical progesterone throughout my pregnancy. And then to take it after I knew my breast milk was established with my son to just kind of optimize my hormones, because that just declines naturally with age. And I will gladly take estradiol as from the time comes.  So we are a big fan of bioidentical hormones for the right demographic who does need it. But for younger women, we can often optimize a lot of things nutritionally and perhaps postpone the need for those hormones a little bit down the road.

Melanie Avalon

Is there a reason the progesterone is after the breast milk is established?

Megan Ramos

Taking progesterone might interfere with prolactin levels. So they're kind of contradictory to one another. So elevated prolactin suppresses progesterone levels and elevated progesterone will suppress prolactin levels. So I just wanted to make sure. I unfortunately, due to my weird placenta situation, had to have a C-section. That was not the dream. And my son was born early.  So it was really important to, I worked really hard to establish my milk. Just wanted to make sure that was solid. And once that was solid and my son was growing like a weed, then I was happy to take the progesterone. And it was such a great thing to add in because of all the postpartum anxiety and all that stuff.  And the progesterone really, it's amazing how much hormonal support helps with things like that.

Melanie Avalon

Awesome, okay. By the way, how rare is that double placenta situation?

Megan Ramos

Oh, it's super rare. And it's like 2% of the population. It is more common in women who have done IVF just because of the embryos are like implanted kind of artificially, right? Like it's not just something that spontaneously happens in the uterus. So I guess you're just a little bit more prone to some placenta issues. And of course, I didn't know that.  And then they don't tell you that till after the fact.

Melanie Avalon

man, crazy, crazy, crazy. And also at your clinic, how many patients have you guys treated or how many do you deal with ongoing? Like how many I'm just curious, like trying to get like an idea of like the numbers.

Megan Ramos

Yeah, so we're now entirely online. I was actually just asking for this data for email that I was working on. I think in the last 12 years, we have worked with either between our Toronto Clinic and law online. We've worked with close to 100,000 individuals worldwide.

Melanie Avalon

That's amazing. That explains a lot why you can have so much knowledge, you know, especially when writing your book and a question about your book, there's a lot of debate out there with fasting definitions. I don't know if you saw the study that came out a couple months ago where they tried to have an official like establishment of what the different fasting definitions mean.  I've found it really interesting. So what do you consider intermittent fasting in your book? I found it really interesting that I think what you were calling intermittent fasting may not be what a lot of people refer to it as basically what constitutes a fast, an intermittent fast.

Megan Ramos

We at the fasting method classify things like 12, 14, 16, 18 hours of fasting, especially when done daily. We consider that to be just good time restricted eating. Why? Well, following these strategies, you know, we don't often see things like PCOS or type 2 diabetes reverse like at all, maybe very mild issues of insulin resistance are resolved.  Maybe, you know, if you're early on in your journey and you it's been just a few years of you carrying that freshman 15 still, it can easily be lost with those journeys. But unfortunately, we have a very sick North American and sort of, you know, global population, severe type 2 diabetes, severe insulin resistance and metabolic health problems. And those just don't cut it for fasting strategies.  So we classify those as just good eating days, how you should eat in between fasts to maintain the progress that you've made with your fasting, and how you should just eat for optimal health and longevity and just sort of good daily shorter fasting practices that we do know have disease preventing benefits down the road.  So like something like 14 hours of fasting has some really great benefits of preventing metabolic related breast cancer and woman. These are great things that we should be doing all of the time to sort of maintain good health and free disease prevention.  But for actual disease reversal, and especially when we've got a lot of that body fat that's super stubborn, and there's a lot of insulin resistance, they're keeping it on, we don't find those to be effective strategies. So those are those time restricted eating protocols, you know, they're daily fasting protocols for for maintaining health and for disease prevention, once you are healthy.  Now, what we focus on is fasting protocols that really target the insulin resistance. And in an insulin resistant individual, we really don't see those insulin levels fall enough for healing and some sensitivity to begin to develop until we approach the 24 hour mark.  So people that we work with and how we define fasting is we call it therapeutic fasting, we're fasting to treat condition we're fasting to treat insulin resistance. So we do combinations of 24, 36, 42, 48 hours of fasting, and then occasionally some extended fast.  So sometimes, you know, it's funny, because like I see all of the same stuff as you and your listeners, and like an extended fast is 24 hours, I actually just had someone the other day tell me they did an extended fast or 24 hours. By definition, though, an extended fast, you know, for us is 72 hours or longer. And these are the therapeutic strategies we help to reverse disease.  Now when someone's disease is reversed, we don't keep up with therapeutic strategies. I mean, you do a therapy to treat a condition and hopefully you can alleviate that condition and go to maintenance. And then we switch to time restricted eating protocols to maintain after that.

Melanie Avalon

It's definitely a slightly different view than I think a lot of people have. We had a question about the 72-hour fasting. Sherry said, I heard her say on one podcast that 72-hour fasting is easier for menopausal women. Can you ask her about it and what that looks like? For example, is that three fasting days and then four days with two meals?  I will say for listeners, get the book because it will go through, it goes through all the protocols and what this actually looks like. Just to briefly answer, when people are doing those extended fasts, are they fasting completely for 72 hours and then eating regularly the other days or what does it look like?

Megan Ramos

Yeah, for individuals who want to do 72 hour fast. So for like cycling woman, we would do it in the first half of the cycle in that follicular phase before ovulation. And then in menopausal, post-menopausal woman, there's a lot more flexibility. You can do it any time. That feels good. We would have people do three days consecutively, like say from Sunday dinner to Wednesday dinner.  And then that ends up with four consecutive days of eating, usually two to three meals a day, often though people will break it up with a 24 hour fast somewhere in the middle. So we commonly see people fasting, say from Sunday dinner to Wednesday dinner, and then maybe doing a 24 hour fast on Friday until from Thursday dinner to Friday dinner, just to kind of break up those four days of eating.  I know this sounds really intensive, and it has been a common comment since my book came out, is that I'm the crazy fasting lady. And these are intensive strategies. And they're really only meant for short term treating a condition and then moving on from it. And I'm all about the minimal effective dosage. For those of you who are listening, you might be a little bit scared of these things.  We always start someone off slowly and work our way up. And we always see what is the minimal effective dosage of fasting required for them. And I hate to say it, but unfortunately, in cases of severe metabolic disease, severe insulin resistance, we often do need to do some of these therapeutic fasts. Now, I would say there's never really a need to do a 72 hour fast.  You can do one if you want to do one. Sometimes people really like packing all their three days of fasting back to back. You know, we used to have women do a Monday, Wednesday, Friday fast in our clinic.  And they would come in and say, can we please just do them all in one day, because or sorry, an all in one stretch, because once we get into a fastest state, it's easier to stay there than to have to bounce back and forth throughout the week. Whatever is most sustainable, sure. But we do these therapeutic strategies, hopefully, you know, not longer for than six months.  If someone's able to be consistent with them, you know, before we start to turn down the fasting dial. And if someone's making great progress, you know, doing 24s, then like, hey, if it's not broken, don't fix it. And we definitely work to keep them there.  But there are people who do need to do longer fast, there is definitely a time and a place, you know, for doing something like 248 hour fast, and maybe occasionally, you know, doing a 72 if that's easier for you. And there's a time and a place for that. And I feel like there's not a ton of resources out there.  So I think sometimes I get labeled the crazy fasting lady, with these long protocols, but there is a time and a place. And I wanted to make sure we could provide a voice for all women, we a woman who have great success with 24s, but for the woman that just find it easier to do some little longer fast to get to their goals as well.

Melanie Avalon

A question about the mechanisms of action there with the longer fasting. How much of it is just due to the low insulin versus other things that are happening with fasting?  And my follow-up question would be, can you sort of hack it by doing like a 36-hour fast and then a super low insulin meal, you know, and like, so sort of like maintaining that low insulin but not fasting as long, or is it really about the fasting hours?

Megan Ramos

A bit of both. Someone's looking for weight loss. Jason actually just interviewed me. It was the funniest thing. We spent 20 years just talking, and it was just weird to be talking on camera with him, interviewing me. I know that interview's not going to air well into next year, but he shared on the interview that he recently... It was just going to work out in his schedule to do a three-day fast.  He wanted to do one before seven, the holiday hoopla. He took a very tiny, next-to-no insulin-producing meal every single day during that fast. You can absolutely do that. For women, if I was someone who wants to do a five-day fast and I need something like a slice of avocado in the middle of that fast to be successful, then do it.  If they're really looking to knock down the insulin and suppress it for a long period of time and to try to burn as much fat, do it. Absolutely. Go for it. There are some other health benefits.  In certain cases, like if someone was a cancer patient, we would probably want to do three days to focus on water and electrolytes because we would really want to optimize the cellular recycling process called autophagy. Autophagy is this physiological cellular recycling process that can be activated by nutrient suppression in the body. That is beneficial.  A lot of cancer patients seek it out as just one of the tools in their toolbox of therapies that they're using in conjunction with regular medicine. We tend to really try to optimize that autophagy process. We would try to minimize nutrients being added to that particular time and just stick close to water and salts and some Epsom salt baths.  Sometimes people feel too like when they are losing weight, they're starting to get a little bit excess skin accumulation and they want to try to minimize that. That's another instance where we'd see someone really want to optimize autophagy happening in the body so we can get that breakdown of the connective tissue happening there.  If that was the goal, then we would say, okay, autophagy really peaks at the 72-hour marker into a fast. We would want to do a three-day fast then if that was someone's goal and we would try to minimize nutrient intake during that particular time. There's really no black or white answer. There's really no wrong or right way. It just depends on what that particular goal is of that specific fast.  Sometimes there's a time and a place. I think Jason's like he had some broccoli and green vegetables. Nothing that sounded appealing for me even on an eating day, but I don't like broccoli, but I'm pretty sure that's what he ate. That's fine. People have avocado slices here or dill pickle there.  That's also fine if they're just trying to lose weight, but otherwise it depends on what their goals are, how we would guide them on that.

Melanie Avalon

Yeah, so actually the second part of Sherry's question, she was the one asking about the 72-hour fast. She said, can a salad with oil and vinegar be a fasting aid? And she also said, I'm so glad you were interviewing her.

Megan Ramos

So Jason, yeah, but it can be but it is it is a fasting aid. So, you know, I'm not going to say that you're in the fastest state for that entire duration, you are going to be removed from the fastest state for a period of time.  But if it's something small, if it's something that you know, if you're having something like leafy greens, and it's there's not going to be that insulin response is just so minimal. And you add a little bit of olive oil, for example, but not a lot, just like a little bit.  It's not a ton of fat, you know, it's really not any different than adding a little bit of something like heavy whipping cream to your coffee during a fast. So it is fairly equivalent in that sense of someone needed something.

Melanie Avalon

And so, to clarify, we're talking about people using this to do those longer fasts, not like their daily fasting window, just for super clarity there. Speaking of daily fasting, you mentioned this in the book, but how do you feel about people doing one meal a day every day?

Megan Ramos

No, I hate it with a fiery, fierce passion. And I'm fortunate that there's a lot of wonderful female fasting advocates out there who also feel the same. It is just such a detriment we've seen to women's metabolism over time. We run into nutrient issues over time, and then women are feeling like garbage, they're starting to gain weight. So with one meal a day, these are kind of the big issues.  So you're doing the same thing day in and day out. There's really not that much intermittent with it, and the body does begin to adapt versus doing three 24-hour fasts a week. So if you're doing just one meal on Monday, Wednesdays, and Fridays, it's intermittent. One day is one meal, the next day is two meals. You know, then one meal, two meals, one meal, two meals.  So there's change, there's variety there. Your metabolism is getting fed different amounts of metabolic energy every other day, and it keeps it guessing, and it keeps your metabolism running well. But when you do the same thing every single day, your body adapts, and it slows down your metabolic rate. So I always talk about, you know, you have a house, we all have household incomes, right?  So if your household income is reduced by 40 percent for whatever reason, at first you would overspend, likely. If it was abruptly reduced by 40 percent, I mean, you would still maybe have expensive car bills and other luxuries, like gym memberships and things that you might not be able to afford afterwards. And so you might go into a bit of debt.  And then over time, you learn how to avoid accumulating debt month in and month out. And you cut back, you know, you might cut back on groceries. You might sell one of your two cars and get a public transport pass. You might get a Netflix subscription instead of going to the movies. You might just stream stuff versus paying for cable, like that type of thing.  Like you figure out how to cut corners and avoid going into debt every month because your monthly income has been reduced and you learn to adapt over time. And so our bodies are we feed our bodies and we give it, you know, metabolic dollars every day in those meals.  And when you reduce it every day, just to sort of one meal and say you you're still eating a very colorically dense meal at that one meal, but you're still reducing it, say, by about 40 percent day in and day out. And your body over time will overspend metabolic dollars and you will see some weight loss happening. But then it says, OK, you know, this is becoming consistent now.  And I know how to plan and I'm going to cut costs and reproductive function. And you're going to cut costs from cognitive function, cardiovascular function. And I'm going to adapt to this new budget and then your body adapts to that new budget by slowing down your metabolic rate to match your new metabolic intake.

Megan Ramos

And that's what we see happening when people do one meal a day. Also, it's just not enough protein. It's pretty much the bottom line.  And, you know, too, is that a woman, especially as we get older, our protein demands increase and it's so important, you know, to have good protein intake because it plays a huge role in maintaining really good hormonal health, not just, you know, when I talk a lot about insulin hormone, but sex hormones and we need the protein.  The protein is really an important building block along with dietary fat as well for good hormonal health as we get older. So our demand for it actually increases, decreases as we age.

Melanie Avalon

I'm a huge fan of protein. It's ironic. I'm airing the week that we're recording, not that this is coming out. An episode with Dr. Michael Greger, who's very, very big in the vegan sphere. And he was talking about how the one thing correlated to longevity consistently is a low protein diet. And I think it's really confusing to people when they get completely different perspectives on that.  It's interesting. I feel like I'm a unique unicorn in a one experiment with this because I have been doing one meal a day for, man, over a decade. I eat super high protein though, like pounds and pounds of meat and fish and seafood at night. And then I tend to alternate between higher carb days versus low carb days.  I don't know if maybe that is enough to keep my body guessing or keep my metabolism going. I mean, it's worked for me so far, but I also realized that I'm very unique in that. Like the amount of protein I eat in my window is like a shocking amount. So I don't know if you've worked with any unicorns like that.

Megan Ramos

No, there are definitely unicorns out there. I'd say it's not like the bulk of individuals, though. But I love your strategy of changing up your macros. Often, you know, there are times where people cannot fast for whatever reasons.  You know, like we won't necessarily fast somebody that's going under evaluation for an unknown medical condition, because then they always just kind of like blame the fasting, even if it would be helpful. If there's these instances that pop up or someone just, you know, they're going through a stressful time and, you know, they haven't combated stress eating yet.  But, you know, they can make the commitment to eat healthier. And we'll change up their macros. So weeks of higher protein, then weeks of higher carb, weeks of higher fat, and more moderate protein and carbohydrates, which is mixing up those macros. And it's been incredibly beneficial in their health journeys.  And it has made an improvement in their insulin resistance levels as well, in sort of the absence of doing longer fast. I don't necessarily know if it would take like an insulin dependent diabetic off of insulin. I don't believe so. But, you know, there's always going to be a unicorn in every case. But it is a it is a great strategy.  We are big believers in our program of just kind of rolling with the seasons. And some seasons will be higher carbs, some will be higher protein, some, you know, will be higher fat, and just kind of really making sure that you're prioritizing what you're eating locally, because it's going to be more nutrient dense, and just kind of embracing those changes in macros as the seasons change as well.  So there's a lot of, you know, Davis and Claire, I know he can be controversial too, like Michael Greger and these other guys, but he's got some interesting data on the benefits of changing sort of macro ratios for a longevity. And when we've put that into clinical practice, we've seen some really interesting outcomes and improving health span as well.

Melanie Avalon

I've had them on the show twice so I'll put links to that for listeners. How do you feel about and have you seen a change in your patient population either by numbers or by just their condition they're coming in with due to JLP ones?

Megan Ramos

We usually, it's very common for someone on our team to tell me that they had a consultation with someone and they said, I must be the only person that this didn't work for. And if I had like a quarter for every time I heard that, all of us pastors would be like living up on a Hawaiian Island. So there's that.  So one thing, you know, it goes to show that we've got to really sort of fix our relationship, our food choices, the frequency that we eat, our behavioral aspects around food. There isn't a magic bullet, especially that one that will work for everybody. So some people can continue to snack all day long on process, they refine foods and they might get some weight loss from these GLP ones.  But we do see a substantial number of individuals that say, Hey, you know, this doesn't work for me. I must be the only one because that's kind of what the media has a believing right now. It's just like, no, like welcome to like 10,000 people who are just just like you.  The other thing we see is nice people that have taken them have had some positive experiences with fat loss, but then have developed some side of effects, have had to stop taking it and then have regained the weight because they didn't change how they ate the frequency that they ate or their behaviors around food. So it's definitely not a miracle bullet.  There's a time and a place for them though, you know, when they did come out, I know Jason would put people on them short term, that would be the goal just to help get kind of appetite under control, but we would never want them to be on them long term where they might experience some problems down the road. We again, don't think it's a magic bullet.  I will never forget it was the start of COVID lockdown in Toronto at the time Toronto was really kind of crazy with it. My dad is a very social outgoing lawyer and he was then just home alone and isolated and he was eating his feelings. Sorry, dad, I'm sharing this with everyone and he had made such great progress with his diabetes through fasting. He had lost tons of weight.  He was off all his medications and A1C was like moving in the great direction, but this COVID just kind of sent him like so many other people into like a loop of poor habits and eating and his numbers all slid and Jason called me and he's like, I'm seeing your dad this afternoon and he's like in a telehealth appointment and he's like, what do you want me to do?  These are his numbers and he's like, I imagine, you know, you're aware of what's going on with his eating as well. And I said, just put him on a was epic for three months, like just give him three months to get it together, to get him to acclimate to what's going on, give him a little bit more control over his appetite at this particular time.  And Jason said he agreed, but he wanted to make sure that I was on the same page and that's exactly what it did. You know, it helps suppress things a bit, you know, for him to kind of, you know, get used to what was going on, make a new health plan to get back into action.

Megan Ramos

And after that three months, he didn't need it anymore. And he was rolling along and doing just fine and was able to maintain, you know, good habits and eating and fasting afterwards and get back his numbers. So, you know, we don't say never, you know, in our program, there is a time and a place.  I know clinically when we're working with someone in the clinic, you know, we try to make it not as long term as possible. It's not a magic bullet. That's for sure what we've seen as well.

Melanie Avalon

I really love and appreciate that perspective. And yeah, I think they're clearly there can be very powerful and potentially therapeutic if used correctly. I feel like they're just a severe lack of education and correct implementation. And yeah, so that that's fascinating. Another question. So with the holidays and everything, do you have tips or tricks for people?  Should they consciously try to be more restrictive? Should they use that as a time where it's seasonal and that's a time to boost their metabolism? And we've mentioned avocados a lot in this interview. And I keep getting flashbacks to something that you share in your book, which is your 90 minute hack where you can determine if you're actually hungry and then you think about an avocado or something.  Yeah. So what are some tips and tricks for holidays and approaching them? And what is this 90 minute hack thing that you have?

Megan Ramos

Yeah, so you know, when it comes to the holiday season, there's there's all different kinds of things like, you know, trying to be the one that hosts it so you can play on the menu or offer to bring like charcuterie or different side dishes so you do know that there's something that you can have. I know here in the I live in the Bay Area now and we always go to our friends on Thanksgiving.  And I just know now to offer to bring my own side dishes and I make amazing brussel sprouts with pancetta and they love it. So everybody's excited. And then I'm mostly excited because I know there's a side dish there that I can really lean into. And I'm not stuck with bad options. So and most people who are hosting don't mind if you offer to help because it is a lot.  So I mean, there's things like that. In general, I do recommend eating and prioritizing, you know, some good fatty protein or fatty fiber source depending on where you lean more plant based and more animal based fatty protein or fatty plant or fiber source before you go. So you're nice and satiated before you show up to the party.  We do have a 90 minute hack to help you reach satiation at the start of your journey. But we have a 90 minute holiday hack is that when you show up, I know I'm unfortunately won't be home for Christmas this year. But when we are, you know, we show up at my mom's super early. So you can do like the presents, the old school presents, they get to be kids again, even like the age of 40 and 37.  And then we're just there for the whole day. And there's like food being put out after food being put out. But like the real main meals, not, you know, coming to like five o'clock, you know, you get there early, and there's all these appetizers and hors d'oeuvres. And I encourage people, you know, treat them like a mini meal.  So you're showing up, you know, dinner is still going to be a few hours away. Eat for 90 minutes, but cut it off. So like you're not grazing, you know, for three hours, you get to participate, you can focus on the foods that align with your sister or with your principles and food values. And then everybody thinks you're participating, and then you cut it off. And then you wait until mealtime.  And during that time, you know, enjoy different herbal teas, like mint tea that might suppress your appetite carbonated waters, flavored carbonated waters, just to help what we often see so much as people say, no, I'm going to fast to dinner, I'm going to show up at my sister's house at noon, and dinner is not going to be to six. And I'm going to avoid all of the pastries.  And I'm going to do a 24 hour fast. Don't do that. Please don't do that. Like wake up that day, have breakfast, prioritize the foods that make you feel satiated for that meal.

Megan Ramos

You know, so for like my family, we might have like bacon, eggs and avocado, you know, for for that meal.  And then we show up and we do enjoy some appetizers and dessert orders, like we don't shoot ourselves in the foot, and then spend, you know, six hours debating with people that you know, why we're fasting, and why we need to fast and why they should be fasting, like no one wants to get into that over the holidays. And so we show up, you know, we give by giving ourselves permission.  So this whole concept of food freedom that Melissa urban sort of coined, to a certain extent, you know, you're giving yourself permission to have something that way, you don't go overboard with it, right? When we show up with the attitude, we're not going to eat anything.  And we're going to fast into dinner, almost every single time, you know, the patient or client would come back and say, Well, I ended up eating everything. But when you show up and say, No, I'm going to eat the foods that align with my values, and I'm going to eat them for 90 minutes, and then cut off the timer. At that point, people then do stick to the foods that resonate with their values.  And they do cut off the timer, and then they avoid all of this family conflict. They are feeling satiated then because they stuck with the foods with their values. So that's a sort of the 90 minute recommendation. And a lot of our communities found that to be helpful.  And then if you are going to have, you know, something a little bit special at your at your meals, I do know, like whenever we're in Florida for Thanksgiving, my husband loves his godmother's like sweet potato casserole, and he will have it.  But he will eat everything else first, all of the other protein, fiber and fat sources that he's going to have, he will eat all of those first, and already feel pretty satiated before having any of that sweet potato. And then he's able to control his portion size. What we found was on, you know, all the days like that.  And this happened to me, I remember it was like my first Christmas, and I was going to eat my mom's roasted potatoes. And I was like a little four year old, I put all the food on my plate, and they went for the roasted potatoes first. But I ate roasted potatoes on a mostly empty stomach, my insulin spiked, my glucose was spiked, my appetite was spiked.  And then I was like a bottomless pit and like people stared at me. And then I knew for the next holiday, wait, no, the great fatty protein and fiber. And I went to have some of her special roasted potatoes, I could only eat a small portion of them because I was full. My appetite was suppressed, meaning all the other good foods.  So save any indulgent items that you have for last, fill up on the good fatty fiber protein sources first. And if you can use something like vinegar, so if you can appropriately add it to a particular carb dish, like if you are having potatoes, for example, maybe not sweet potato, casserole, but something else add some vinegar can make a big difference as well.

Melanie Avalon

Wow, that's so cool that you intuitively figured that out as a kid. You know, that's amazing with the potatoes.

Megan Ramos

I was like 27 at the time, but I felt like a kid the first time. I'm like, oh, I'm going to eat all of this. This is my Christmas present, potatoes. And it just went horribly wrong very quickly. I didn't have any self-restraint. And the next time, I'm like, no, I'm going to treat them like dessert on my plate, and I'm going to eat them last. And I had a lot more control that way.

Melanie Avalon

I love that. A final question about your book. So you were mentioning earlier how some people interpreted the book a certain way with what you're prescribing when it comes to fasting. So I'm curious, since releasing the book, also since having your pregnancy and everything, is there anything that you would go back and change or adjust with what you wrote, or do you want to write another book?  Have your thoughts evolved.

Megan Ramos

I would love to write a book on perimenopause and strategies. I think the essential guide to intermittent fasting for women, there was some information there for perimenopausal women, but I think it's such a unique time in a woman's life where there's so many hormonal changes going on. And there's a whole different game set of strategies.  And we gave some of the basic ones, the common ones in the book for effectiveness, but perimenopausal women trying to lose weight and treat or prevent insulin resistance from developing, they deserve their own book. There's a lot there. Of course, I would also love to write one for women who are struggling with PCOS geared towards fertility and positive fertility outcomes as well.  So we tried to make the essential guide to intermittent fasting for women with key pieces of information for women across the whole adult hormonal landscape and spectrum there. So there's definitely something for everyone, but I feel like those were two demographics where there could be whole books just dedicated to those particular things.  And then of course, the post-menopausal women, I think, have so much freedom and liberty with fasting and even some nutritional choices to a certain extent. And I wish if there was a second version, I could have highlighted that a little bit more.  So I know when we do our book club at the fasting method and we go through the book, we really try to highlight that so that the post-menopausal women really feel heard and seen. So those are some reflections now that it's been over a year. Those are some of my hopeful goals for the future, once I've slept for a few consecutive nights at some point, things that I'd like to work on.

Melanie Avalon

And to clarify with the perimenopausal woman, is that the category of woman that needs to be more, I guess, concerned about overfasting? It's interesting because a Megan, another Megan, she said that she really appreciates you. She said she heard you. She said hearing her on a podcast changed the way I think about my health and has helped me enormously.  And then she wanted to know, for a woman approaching perimenopause, how can they make sure they're not fasting excessively? So my question there is just, is perimenopause where that is more of an issue?

Megan Ramos

It can be, absolutely. Sometimes less fasting is definitely more in terms of results. And when we work with a perimenopausal woman, we need to see the labs and we really customize it. We really want to make sure we're being ultra sensitive to thyroid. When you're younger or even a bit older, you can beat up your thyroid a little bit, but we don't want that to happen during that time.  We really want to make sure we're loving and nurturing our thyroid. I know at adrenal glands, there's so many that's so important for just overall sex hormone balance. Taking a look at the different sex hormone balance, taking a look at their cortisol, and really planning their particular fasting and eating strategies around that.  Even from when we would work, have someone do an intensive workout, changes if they're having cortisol issues, especially going through perimenopause. There's a lot of stuff that we, I think it's the most time in a person's life where fasting really needs to be personalized based on a whole handful of hormones. Often less fasting is more and being really creative about how you structure it.  I think maybe millions of people have heard both Jason and I say, breakfast. But a lot of the times, we make breakfast one of the staple meals for the perimenopausal women. Especially when cortisol is high, we want to optimize the conversion of Friti 4 to Friti 3 in the morning rather than reverse C3. We see all these reverse C3 issues. We want to optimize that.  We don't want to make it worse throughout the day or in general. We often will implement breakfast, whether we're doing some shorter fast or are still doing some longer therapeutic fast. It's very personalized and we do tend to turn the fasting pile down a bit during this particular stage in life.

Melanie Avalon

I, and I'm sure others will eagerly await hopefully that book when you get some more sleep in you. Thank you so much, Megan. I really cannot express enough my gratitude I have for everything that you're doing. And literally, you are so wildly popular with my audience. It's insane.  And even having co-hosted the Intermittent Fasting Podcast with both Cynthia Thurlow and Vanessa Spina, they both say the same thing that just, you know, whenever they have you on their shows, it's just everybody is obsessed. So, um, thank you so much for what you're doing, friends, definitely get the essential guide to intermittent fasting for women.  I will hopefully can have you back in the future when you have a new book and some sleep in you and all the things.

Megan Ramos

Yes. Thank you, Melanie. And thanks to all of your listeners for everyone's support. And I will keep putting information out there, sleepless or not so sleepless. We will keep getting stuff out there, helping just real practical strategies, you know, because fasting is super doable for everybody, but it is a little bit nuanced, especially for us ladies.  So just keep getting the information out there so women know that it is safe for them, but I feel confident that the strategies that they're doing are safe for them. So thanks everyone for listening to my rambles and happy fasting and we'll see you soon.

Melanie Avalon

Yes, no, thank you. And I almost forgot last question. It's so easy. What is something you're grateful for?

Megan Ramos

Right now, I'm so grateful for everything I've learned about nutrition, because my my son was born early, and he was 1.6 percentile for weight. And it has been a journey, but he is absolutely thriving. And if I hadn't been through all of this, like he's going to have such a completely different life than I have. So grateful. Sorry. Anyways, he's a cool guy.  So he's not going to be part of the puffs generation. That is for sure. And I'm happy for for it. So we can make we can start making changes for the kids to come.

Melanie Avalon

Thank you so much. That is so powerful. I am overwhelmingly grateful. Congratulations to you and your beautiful boy, and have a wonderful year. We'll talk again soon. Thanks, Melanie. Thanks, everyone. Thank you. Thank you so much for listening to the Intermittent Fasting podcast.  Please remember, everything we discussed on this show does not constitute medical advice, and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing a review on iTunes. We couldn't do this without our amazing team. Editing by podcast doctors, show notes and artwork by Brianna Joyner, and original theme composed by Leland Cox and recomposed by Steve Saunders.  See you next week.