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Nov 06

Episode 290: Creatine, Vitamin E, Safe Tanning, Slow Weight Loss, Cheating On Your Diet, Toothpaste, Digestive Enzymes, Leaky Gut, And More!

Intermittent Fasting

Welcome to Episode 290 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

LMNT: For Fasting Or Low-Carb Diets Electrolytes Are Key For Relieving Hunger, Cramps, Headaches, Tiredness, And Dizziness. With No Sugar, Artificial Ingredients, Coloring, And Only 2 Grams Of Carbs Per Packet, Try LMNT For Complete And Total Hydration. For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase!

NUTRISENSE: Get Your Own Personal Continuous Glucose Monitor (CGM) To See How Your Blood Sugar Responds 24/7 To Your Food, Fasting, And Exercise! The Nutrisense CGM Program Helps You Interpret The Data And Take Charge Of Your Metabolic Health! Get $30 Off A CGM Subscription At Nutrisense.Io/Ifpodcast With The Code IFPODCAST

AVALONX Magnesium 8: Get Melanie’s Broad Spectrum Complex Featuring 8 Forms Of Magnesium, To Support Stress, Muscle Recovery, Cardiovascular Health, GI Motility, Blood Sugar Control, Mood, Sleep, And More! Tested For Purity & Potency. No Toxic Fillers. Glass Bottle.  Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist, And Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

LMNT: For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase! Learn All About Electrolytes In Episode 237 - Our Interview With Robb Wolf!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

Introducing... Creatine by Cynthia Thurlow

Ep. 234 Metabolic Longevity and Vitamin E with Dr. Barrie Tan

NUTRISENSE: Get $30 Off A CGM At Nutrisense.Io/Ifpodcast With The Code IFPODCAST

Listener Q&A: Charles - Safe Tanning Bed

For A Limited Time Go To joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

Carex Day-Light Classic Plus Bright Light Therapy Lamp

Listener Q&A: Rachel - Weight loss too slow

Listener Q&A: Darcy - Diet Cheating

Listener Q&A: Deborah - What about Toothpaste?

Primal Life Organics

Ep. 153 – Fix Your Mouth/Fix Your Health: Reversing Tooth Decay Naturally with Trina Felber

Listener Q&A: Ann - Digestive Enzymes

AVALONX MAGNESIUM 8: Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

Listener Q&A: Alyssa - IF and digestive changes

Gut Assist - Leaky Gut Repair Supplement Powder

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 290 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: A 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time, and get ready for The Intermittent Fasting Podcast.

Hi, friends, I'm about to tell you how you can get my favorite electrolytes for free. Yes, completely free. And the feedback we have received about LMNT electrolytes from our audience is overwhelming. You guys love LMNT and I'm so excited because our new offer allows new and returning customers to get free LMNT. On top of that, they're super popular. Grapefruit flavor is back. If you've been having issues with intermittent fasting, electrolytes may just be the thing that you need and/or have you heard of something called the keto flu? Here's the thing. The keto flu is not actually a condition. Keto flu just refers to a bundle of symptoms, headaches, fatigue, muscle cramps, and insomnia that people experience in the early stages of keto dieting. Here's what's going on. When you eat a low-carb diet, your insulin levels drop. Low insulin in turn lowers the production of the hormone aldosterone. Now, aldosterone is made in the kidneys and it helps you retain sodium. So, low aldosterone on a keto diet makes you lose sodium at a rapid rate. Even if you are consciously consuming electrolytes, you might not be getting enough. In particular, you need electrolytes, especially sodium and potassium in order for nerve impulses to properly fire. Electrolytes can easily be depleted while intermittent fasting.

Robb Wolf, who as you guys know is my hero in the holistic health world, worked with the guys at Ketogains to get the exact formulation for electrolyte supplements to formulate LMNT Recharge, so you can maintain ketosis and feel your best. LMNT Recharge has no sugar, no coloring, no artificial ingredients, no junk. They're used by three Navy SEALs teams, they are the official hydration partner to Team USA weightlifting, they're used by multiple NFL teams, and so much more. We have an incredible offer just for our listeners. You can get a free LMNT sample pack that includes all eight flavors. Citrus, watermelon, orange, raspberry, mango chili, lemon, habanero, chocolate, and raw unflavored, and the raw unflavored by the way is clean fast friendly. You can try them all completely free when you make a purchase at our link, drinklmnt.com/ifpodcast. You can get this offer as a first time and as a returning LMNT customer. I know there are a lot of returning LMNT customers. The feedback I hear from you guys, "loving LMNT" is amazing. LMNT offers no questions asked about refunds on all orders. You won't even have to send it back. And this offer is exclusively available only through VIP LMNT partners. You won't find this offer publicly anywhere else. So, again, the link is drinklmnt.com/ifpodcast. And we'll put all this information in the show notes.

And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting, it's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer, and Obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream.

And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup may be playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That's because ladies when we have babies, a huge percentage of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years.

Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means when you put on some conventional lipstick, 30 years later maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life and their makeup is amazing. Check out my Instagram to see what it looks like. Tina Fey even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo, and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well. 

And lastly, if you're thinking of making clean beauty and safe skincare a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally completely worth it. So, again to shop with us go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show.

Hi everybody and welcome, this is episode number 290 of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hey, Melanie, how are you?

Melanie Avalon: I'm good, I started the last podcast off with a question. But I have another question for you for this podcast. How is your creatine going?

Cynthia Thurlow: Good, we're officially told that it will be out before Thanksgiving. I keep getting these vague ideas and we'll make sure we link up the waitlist for creatine so that we can ensure people that are most interested in receiving it. But yes, things are moving forward in a quick direction. I'm hopeful that everything will be out by mid-November. That's what I'm assured will happen. So, it's very exciting.

Melanie Avalon: Why did you choose creatine as your first supplement?

Cynthia Thurlow: I think because-- what's really been a struggle for me as a middle-aged woman is not only the muscle piece, it's so much harder to maintain and build muscle in perimenopause and menopause. And the more research I dove into and the more I talk to colleagues of mine like Dr. Gabrielle Lyon, the more I realized I was like, "This is a huge issue for women." So, last year, I started taking creatine, and in my Stories this past week, I actually put objectively how I've been able to increase the weight week to week, and my trainers like thrilled and so from my perspective, I think for a lot of women, one of the things we have to work very diligently and actively on is not just muscle health, but also brain health. And those are the two key areas with regard to creatine that for me I think are really compelling. And I think my second-- I really believe, I just did a great podcast with Dr. Barrie Tan, talking about the value of a certain type of vitamin E, it's tocotrienols.

And so, the supplementation with that is actually really beneficial for bone health, like significant improvement in bone health. And so, I think my first couple of products are going to really be geared towards helping women find supplements that can be beneficial at different stages of our lives, but also make them accessible. I'm going to take all the research and really understand it, so that I can then provide information and say, "Hey, listen, I myself have no interest in ever being diagnosed with osteoporosis, but I'm doing all the things along with supplementation with these tocotrienols, which is a form of vitamin E and taking creatine to help maintain muscle and bone health, which we know is really, really, important and honest to God, I never thought about it. So, I was probably 45." And I want younger people to think about it before that time period and I want people that are older than me to have options that aren't surrounding the latest potion, pill, or powder which you and I both know is proliferative in the health and wellness space.

Melanie Avalon: I cannot agree anymore and that's interesting about the creatine. It's something that honestly, I think I just disregarded for a very long time because I eat such a high-protein diet that all of the amino acid-related things I've been like a-- well, I probably get getting enough. But I've been hearing more and more it pop up on so many conversations on different podcasts like Dr. Gabrielle Lyon, like you mentioned talking about a lot when Layne Norton was on either Rogan or Peter Attia, he talked about it at length, and I keep seeing it pop up other places, too. And I'm like, "Oh, I think this is something I should be supplementing with." And the timing of it is just working really well in that I'll just start with yours because I know it'll be the best on the market. So, very excited for that.

Cynthia Thurlow: I appreciate all of your support, for everyone that knows Melanie and I are each other's biggest cheerleaders and it's totally genuine, and I love seeing what you've been able to build in your business and how many people you've been able to help with your supplement line.

Melanie Avalon: I'm just excited that yeah, together we can make a change because like you mentioned it's such a sketchy world, the supplement industry. And I already knew that before making my own, which is the reason I wanted to make my own. But now actually being in the process, it's like my eyes are being opened and I've just learned so much. So yeah, listeners definitely vet the supplements that you're taking. Actually, speaking to the vitamin E, because I know that I think there are like eight forms of vitamin E, how do people know which form to get?

Cynthia Thurlow: Yeah, so it's the derivative are tocotrienols and so what's interesting is these are derived from a plant in South America. I mean, Dr. Tan's whole explanation just blew my mind. He was there in South America to do something else and he stumbled upon this plant called annatto. And so, annatto is the derivation of this particular tocotrienols. And there is so much research being done on this derivative. It helps in metabolic health, there are anti-cancer benefits, there are bone health benefits. So, from my perspective sometimes podcast guests end up on our podcast schedule, and maybe at the time you're not fully familiarized with who they are, or their research, or their areas of expertise. And as I was prepping, I was like, "Oh, my gosh, this is actually really, really, interesting." And how do we make it accessible to everyone so that people can walk away from a podcast and be able to take action? Dr. Tan actually has, I don't know when his podcast-- It should be out in November, but he actually has a book on his website that's totally free. So, people can read the research and read his information. He's just passionate about being able to help people. And he's using gold-standard research. It's not epidemiologic research, it's double placebo blinded trials. And it's interesting that something I thought I would have no interest in has now become something I'm incredibly interested in. So, his podcast will be out in November, I forget which date?

Oh, no, his podcast just came out. What am I saying? It was last weekend. I'm getting all my dates mixed up, Melanie. So, that podcast dropped last weekend and we've gotten so much good feedback. And even though someone else who had interviewed him said, "Oh, we know his accent's kind of heavy-- he's got a wonderful sense of humor." He's so passionate, he's like a derivative of Rick Johnson. Like, he's that passionate, he's so like, warm and you can't help but love him. And so, I got off and thought to myself, I have to bring in back to talk about another topic because we didn't really touch on cancer research. But the long explanation of this is that I do think that there's a lot of value, I started taking annatto a few months ago, and I haven't repeated my DEXA but I'll be interested to see what that looks like. Because I've been staunchly opposed to using biphosphates, which for anyone that's listening a lot the bone-building drugs actually technically they build more bone, but it's not strong bone. And so, what got people concerned about them is that dentists were seeing a lot of mandibular necroses, so bone in the jaw being really like spongy and so there's no drug that's without side effects. So, to find something that has the potentiality of really improving the quality of bone because people may not know this, but teenagers as they're growing, they have this acceleration of bone-building potentiality in their bone for so many years because they're growing. And what happens in menopause is that the opposite happens, you've got more bone destruction than you do bone building.

And this is why women in menopause really are at great risk for weakened bones falling and breaking bones progressing to osteoporosis, which is what we want to avoid. If you're a thin Caucasian woman, you're probably already at risk for osteopenia. But you can't compare my bone strength at 51 to someone who's 20. It's like not a good comparison. And so, I remind people all the time that you can do all the right things, but some of us need a little bit more support. And that's another reason why I think testosterone therapy is not something to fear. If you get to a point where that helps you maintain bone mass that's another-- we actually have testosterone receptors on our bones as well as estradiol and progesterone and I think a lot of people forget that it's that loss of hormones that really start to accelerate bone turnover in a negative way in menopause.

Melanie Avalon: Yeah, I'm so happy you're drawing attention to this because I think it's something people just don't think about. People will seem to think that bone is like static or fixed, not that it's like this living tissue that all the process that you mentioned and how much that can be affected by diet and lifestyle. So, now I'm just voting, I vote that you make vitamin E as your second supplement that annatto, what annatto?

Cynthia Thurlow: Annatto, umm hmm.

Melanie Avalon: Annatto I got to find a good one.

Hi, friends. I'm about to tell you how you can get $30 off one of the most incredible ways to track your blood sugar levels. See how your fasting is affecting you, see how your food choices are affecting you, and truly take charge of your health, that would be the NutriSense CGM program. If you've been listening to this show, you know that we are a little bit obsessed with continuous glucose monitors also known as CGMs. If you know how your body is actually responding to different foods, amounts of sleep, stress, fasting, exercise, wine, anything else you're doing in your life, then you can truly achieve your health goals. Whether that's managing your weight, eating foods that make you feel good, having energy throughout the day, optimizing the longevity, understanding your blood glucose is important. And for example, you might even realize that your diet doesn't need to be super restrictive, it just needs to be the right diet for you that is sustainable.

Here's the problem. True, you can check your blood at the doctor or you can randomly check it with a glucometer at home where you prick your finger. The problem is that's just a snapshot. It's a single picture of that brief moment in time. If I've learned one thing from wearing continuous glucose monitors is that your blood sugar can change a lot even from minute to minute. You really need to get a sense of how your blood sugar is changing all throughout the day. 

When you wear a continuous glucose monitor, which is painless to put on, I promise, I have a lot of videos on my Instagram of how to put them on. So, definitely check those out. It gives you a picture of your blood glucose levels 24/7 for 14 days. What I love about the NutriSense CGM program is it has a super awesome app that helps you interpret the data and really understand what's going on. In the app, not only does it track your data, but you can log meals, see macronutrient breakdowns, and so much more. It even gives you an overall score for each of your meals based on your body's response, so you can really find what meals are working for you. Each subscription plan includes one month of free support from a registered dietitian.

NutriSense dieticians will actually help you identify what you should be paying attention to, what that data actually means, they can really hold your hand if you're new to the space or if you're already knowledgeable, then they can provide you even more advanced tips and recommendations. They'll make sure that you adjust your diet and lifestyle to find what you enjoy doing so that you can have long-term sustainable changes. They will even act as accountability partner on your journey. NutriSense also has a private Facebook group for members, where you can find support from other members and learn about their experience. I love wearing a CGM. I just think it is so profound. Even if you just do it once for 14 days, I think you will learn so, so much. But then, of course, lasting sustainable change can take time. Getting a longer-term subscription, it can be an amazing option to consider. 

NutriSense has 6 and 12-month subscriptions and those are cheaper per month allowing you to not only achieve your health goals but also ensure that you stick to your new healthy lifestyle for the long term. It's helped me realize for example how low carb versus low fat affect my blood sugar levels, how berberine has an amazing effect at lowering my blood sugar, and so much more. You can get $30 off any subscription to a NutriSense CGM program. Just go to nutrisense.io/ifpodcast and use the coupon code, IFPODCAST for $30 off. That's N-U-T-R-I-S-E-N-S-E dot I-O slash IFPODCAST with the coupon code, IFPODCAST for $30 off any subscription to a CGM program. There's a reason Cynthia and I talk about CGMs all the time. We love them. NutriSense is giving you guys access to them. So, definitely check this out. And we'll put all this information in the show notes. All right, now, back to the show.

Melanie Avalon: Okay, shall we jump into some questions for today?

Cynthia Thurlow: This is a question from Charles. Subject is "Safe tanning bed." "Have you come across a safe tanning bed for home use? I believe what I'm looking for might be called a hybrid tanning bed. I live in Chicago and there are several months where I can't get good sun exposure. I'm not interested in tanning, just exposure to light spectrums that could mimic what could be attained from the sun. I believe there are beds that can provide UVA, UVB, and even some red light therapy."

Melanie Avalon: All right, Charles, thank you for your question. Thank you for your controversial question. I feel like people get intense about this question. So, I looked up the hybrid tanning bed thing and what I found-- it looks like it's a bed that combines normal tanning rays, like potentially just UVB but maybe UVA as well, with the red light therapy. So, that's all I could find on that specifically. So, my thoughts on this are at-home tanning beds, all I can speak to is what you would look for in a tanning bed and if you are using it therapeutically for the benefit of vitamin D production. And the reason I wanted to answer the question around now is because this airs on November 7, so getting colder, less sunlight and I believe vitamin D levels are so important to our overall immunity and our health in general. People think vitamin D is a vitamin, but it's actually a hormone. The book I'm reading right now, actually, I'm prepping to interview a woman, Dr. Heather Moday, she wrote a book called The Immunotype Breakthrough: Balance Your Immune System, Optimise Health and Build Lifelong Resistance, I am loving it, it's really deep dive into the immune system.

I'm learning so much but I was actually reading the section last night about vitamin D, she makes the argument that it is the most important nutrient when it comes to the immune system. Actually, every single cell of the immune system has a vitamin D receptor, so it's so so important. And then the stats on vitamin D levels and health are really shocking. And I think they really came into play, especially with COVID because then they started doing more studies on COVID mortality or COVID outcome rates and vitamin D levels and there was a really strong correlation there with lower vitamin D levels being problematic for that. So, the point of that is that I think getting vitamin D from the sun or UV rays likely can have some benefits extending a little bit beyond a vitamin D supplement, which is also an option as well. And you can also get vitamin D from some foods, but not in huge amounts.

So, what I actually do and again, this is controversial and I'm not recommending this as a blanket statement, and I don't take skin cancer lightly, but UVB is the ray that actually stimulates the production of vitamin D in your body. UVA is the ray that actually gives you that tan effect. So, it works well because tanning beds tend to be more expensive when they're more UVA because people want to get it for the tan, but it's actually the UVB that you want. And so, you'll often find that cheaper beds are UVB beds. So, what I often do or have done in the past, although I just got my InsideTracker results back and my vitamin D level is too high. I think I've been supplementing too much, but I will get a membership. And at Palm Beach tan, they actually have a pretty good setup where you can get credits, and I just use it in the UVB bed. And I would literally in the winter go in for literally two or three minutes in the UVB only bed. So, that's a personal choice. I cover my face. Yes, that's a personal choice.

So, I can't really speak to at-home tanning beds I assume if you get a UVB tanning bed at home and try that. The red light though is-- it would have completely different therapeutic benefits. And of course, for red light therapy, we absolutely adore Joovv. I do use red light therapy every single day of my life. It's one of my favorite things. And it's really great for skin health, also for reducing inflammation, red light and near-infrared can help with muscle recovery. I use it for circadian regulation. So, waking up in the morning and going to bed at night. So, if you go to joovv.com/ifpodcast and use the coupon code, IFPODCAST you will get a limited-time discount that's J-O-O-V-V dotcom and I think they're going to have some pretty amazing deals for Black Friday. So, if you've been thinking about getting one now might be the time or upcoming might be at the time. So yes, I'm very curious, Cynthia, what are your thoughts on tanning beds?

Cynthia Thurlow: Well, I'm not a fan of tanning beds. But for people that are looking for light exposure, especially people that are more prone to seasonal affective disorder, I like Lux Box, so it's L-U-X and you can get them on even Amazon and a certain amount of exposure in the morning can be hugely helpful. And for anyone that's north of Atlanta, which is mostly United States, you don't get enough sun exposure. It's not just the Midwest, areas of the country where it's really cold in the winters. So, I generally recommend that they get a Lux Box, and then just getting sunlight exposure in the morning can be hugely helpful. The way to think about UVA and UVB light is to understand that UVA light is aging, it will age your skin, then UVB light can burn you. So just to kind of differentiate that those are the two, like the UV lights and what I'm more familiar with. Melanie's absolutely the expert on red light therapies much more so than I am. I actually really like my PMF mat, but that's a completely separate tangential rabbit hole that I'm going to avoid. So, I would say Lux Box is what's going to be most helpful if you're feeling like you need some seasonal-- if you're prone to like depression and just otherwise not feeling good during wintertime because you're not getting a lot of sunlight exposure, a Lux Box is not going to give you multiple spectrums of light but it can definitely help if you feel like that light exposure piece is impacting your mood. And it wasn't clear from Charles' question if that was of issue, but I just wanted to-- this was like a general recommendation I do with a lot of my patients in winter.

Melanie Avalon: Yeah, I think that's great. I actually use a-- it's not Lux Box brand. Mine is called Day-Light, I got it on Amazon, I can put a link too in the show notes, it's on right now. So, I use that and my red light every day. And I love it. Just as a side note, I think it's really important to get-- I don't know how often you should do this but going to a dermatologist and just having them check your entire body for any potentially cancerous growths on your skin can be really helpful. My mom actually recently went through that, and they did find one and they had to like take out a whole chunk of skin. And not to say it's fine, but it can be fine if they find it early. That's why getting those checks can be really important. It's really intense though how much skin they have to take off just to like, even if you have just a tiny little freckle with cancerous potential.

Cynthia Thurlow: They have to get clear margins. Yeah, they thought I had a squamous cell on my forehead this summer. And so, they took like a punch biopsy, it turned out to be fine. But you definitely want to be getting your skin shocks every year. And to do with them well, you have to be pretty undressed. So, if they're doing it and you're just sitting on an exam table and you're not in a paper gown without your bra and your underwear on, then they're doing you a disservice quite honestly.

Melanie Avalon: Now I'm inspired, I need to go get one. This is inspiring [chuckles] this is action. This podcast is having effects on my life.

Cynthia Thurlow: Yes. Take action people.

Melanie Avalon: Yes. I'll do it. If you guys do too. Okay, shall we go on to our next question?

Cynthia Thurlow: Yes.

Melanie Avalon: So, this question comes from Rachel, the subject is "Weight loss too slow." And Rachel says "Hello, IF community. I've been clean fasting now for about six months and although I have lost some weight and inches, I feel very defeated and that the weight I'm looking to shed is just not coming off fast enough. Sort of looking for ideas on how to get the process moving quicker. Here is normally what I do each week, 20 to a 22-hour fast each day with no more than a 3 to 4-hour eating window sometimes 2. I try and do a meatless Monday with about a 42-hour fast a couple of times a month. My fast is completely clean with just water and black coffee. I try and limit my carb intake although I am not completely rigid. I do feel great with fasting and I know you need to eat what feels good to you but maybe I'm not making great choices. I'm normally a pretty healthy eater, lots of veggies, not a lot of meat, but just sort of feeling stuck. I'd a few medical things this past year and I wonder if my body is busy healing rather than shedding weight. Thanks for reading and hope to hear back. Love all the books and the podcasts, by the way, best, Rachel.

Cynthia Thurlow: Well, Rachel, thank you for your question and I mean there is a lot of different variables here when I see that you've been clean fasting and you're frustrated with weight loss resistance. I really start with the basics, what is your sleep like? How are you managing stress? Are you consuming an anti-inflammatory diet? I know you mentioned you're trying to limit your carb intake and I do encourage women if they're weight loss resistant to actually track their macros like to know what you're really eating and chronometer is a free app. They really do a nice job, but I would track total carbs not net, net is a cheat that's a byproduct of the processed food industry. In order to deflect attention to what we really need to be tracking. I would make sure you're eating enough protein, especially if you've got a very narrow feeding window that's another concern, your body may think you're not eating enough food. That's why I think those OMAD situations can be problematic. You can further slow your metabolism, especially if you're not seeing some degree of weight loss or changes in body composition. I think a great deal about are you lifting weights. What's your gut health like? And obviously testing is helpful for that, what toxins are you exposed to, and then you mentioned that you're doing a clean fast, you're limiting your carbs, you're not eating a lot of meat, it doesn't per se have to be made. It could be poultry, it could be fish, it could be eggs, all can be helpful. And then you mentioned you've had some medical things going on, and I don't know what they are. So, it's hard to say if there's a degree of inflammation going on in the body, if you're healing from surgery or healing from an illness, I also don't know from your question how old you are. So, if you're 35 or 40, things can get a little more complicated as you get older, it doesn't mean that it's impossible. So, there are definitely things to think about. I don't like any women to get really rigid and do the same thing every single day.

So, varying your fast is important, making sure you're sleeping, making sure you're managing your stress, getting enough protein in, tracking your carbohydrates, alcohol is a sneaky thing and for some people they don't even register that our bodies will process. Alcohol is a toxin, so if you eat a big meal, and you have a couple of glasses of wine, your body is going to prioritize processing the alcohol before processing the rest of the food which can get stored as fat. So, a lot of things to think about-- certainly you can write us back and give us a little bit more information. But that's kind of my first pass at your question is that there are other things that are going on, we get healthy to lose weight, so we haven't yet determined what's going on. And, if you're really struggling that much, I would encourage you to see your primary care provider, get some lab work done, find out what's going on with your thyroid, find out where you are in your cycle, that can also impact success.

I think that would really be helpful. looking at fasting insulin, I talk about this a lot. Maybe get a glucometer or CGM to determine how good is your blood sugar control. You may think that you're doing really well with your food choices but then you find out that you've got a sustained high blood sugar all day long, and your body perceives that you're under a significant stress and duress. And so, looking and getting a little bit granular about some of those things, I think would be very helpful.

Melanie Avalon: I thought that was very comprehensive. Yeah, so I'm just thinking if she's doing a one-meal-a-day situation with no more than a 3 to 4-hour eating window sometimes 2 like she says, and she's purposely not eating a lot of meat and having a lot of veggies. So that's a lot of volumes. It's hard for me to see how she's getting a lot of protein in that window. And protein is the most satiating nutrient, it's the nutrient that provides the most, building structure for the body, and also from a metabolic standpoint, it stimulates the metabolism that actually requires energy to break down. So, sort of exciting when people are at this place where they have the potential to increase the protein because I think they can potentially see a huge difference if they focus on that specifically, especially when it comes to shedding the weight. So, either adding in protein or switching out some of what you're eating for protein-rich sources, instead, I think might have a huge effect on that. I've also found that-- and I don't want to make a judgment either way. But sometimes people kind of indicate that maybe they know that there could be better food choices that might work better, but I think they just need somebody to tell them that.

And it's hard to know if that's the situation, but it's language like, "I know you need to eat what feels good to you but maybe I'm not making great choices or I'm normally a pretty healthy eater." And so it might be that you are making great choices, and you are a pretty healthy eater, or it could be that maybe there are some things in there that aren't serving you as much as they could be. So that's more like a psychology of it. There's a lot of potential there for making changes in what you're actually eating in addition to all of the lifestyle things that Cynthia pointed out.

Cynthia Thurlow: Absolutely.

Melanie Avalon: Alrighty, shall we go on to the next question?

Cynthia Thurlow: Yes, this question is from Darcy. Hi, "I cheated on my diet while I was supposed to be fasting. Can I just do a 48-hour fast to help get back on track?" Thank you.

Melanie Avalon: So, I love this question because I think it's one of the shortest questions we've answered on the podcast that actually speaks to something that is a huge topic. And it's the idea-- Well, first of all, can you do a 48-hour fast to help you get back on track? Yes, you can do anything and the reason I'm pointing that out is people write us all the time. I think I talked about this recently on another question on another episode, but it's like people think they need permission to do things in their life from-- I don't know from us, from society. You don't need permission from anybody to do anything. I just want to put that out there. So, yes, you can, the question would be, would that be a good thing to do? I think like that's the framing I would put on it. So, I have very mixed feelings about all of this. In general, I think there's a huge benefit to having an intermittent fasting pattern that works for you. And if you have a one-off situation where you "Cheated". Well, first of all, I think we should reframe it and not even see it as cheating, because I mean what is cheating? What does that even mean? You just chose to eat something that wasn't in line with maybe what makes you feel best instead, like it's not really cheating in my opinion. I think semantics are really important. And how we frame these things if you have a moment where you ate things that don't agree with you, or that are inflammatory, or that you feel the need to atone for which goes back to that cheating language. So, you can fast longer and that will very likely help with reducing inflammation, getting you back into the fat-burning state, it can have a very positive beneficial beautiful effect. I encourage people to fast longer if they think it will make them feel better. The sticky thing is I don't want people doing that out of fear and out of a feeling that they have to fast to undo what they did. Because it can very quickly become a disordered eating mindset, it can very quickly become over restrictive. So, in the ideal world people would follow the diet that works best for them. And maybe they have moments where for whatever reason, they're going to eat foods that are going to have side effects that are going to have-- are going to make them not feel so good on the flipside, and that's okay, too. And how you deal with that is okay. You can just keep on with your normal fasting window. If fasting longer physically makes you feel better. I mean I think that's fine. I just think people can get into a pattern like a binge-fast cycle where they're either binging or having these foods that make them feel bad and then responding with an atoning long fast. I think it can quickly spiral into a mindset that can feel like you're in a trap, like we want fasting to be freedom for people, we want it to be a good thing, we want it to bring benefits to people's lives and enhance their life and make them feel better. We don't want fear and insecurity and feeling like it's something they have to do to make up for their choices. So, yeah, I could go on and on about it. But Cynthia, what are your thoughts? 

Cynthia Thurlow: I think our external dialogue is reflective of our internal dialogue. And when you say you cheated on the diet, it's very pejorative, you're judging yourself and in fact, what you should say is today I didn't eat as ideally as I would like to and tomorrow is a new day. So, reframing that whole judgment of yourself is really important. We have to give ourselves grace. None of us are perfect. I have days when my macros are a mess. I always reframe it as like, okay, tomorrow's a new day, I'm not going to-- I'm not going perseverate or overthink it, I'm just going to make tomorrow a better day, I'm going to make better choices tomorrow. Now, when we blow the motherlode, if you will, on a meal or a whole day of not eating ideally, the things that I think are important to lean into is adequate sleep, lots of hydration, eating lots of green things. And by that, I mean salad and if you tolerate non-starchy vegetables, hitting your protein macros, getting some exercise, and if it's appropriate for you, you can do a longer fast, you shouldn't punish yourself.

I think a lot of people it's a self-flagellation behavior where we feel like, we really have to treat ourselves unkindly. And human nature's we are not going to be perfect, life is perfectly imperfect. And so, Darcy, I'd really encourage you to reframe those thoughts and to be kind to yourself and obviously you don't need our permission to do a longer fast, but there are lots of different ways to get yourself back on track when you've not eaten as ideally as you would like to. And first and foremost is that mindset piece. So, the judgmental way that you're describing what you did, I would encourage you to say today wasn't the best day and that's okay and tomorrow I'm going to get back on track and that's really the way to reframe it and move forward.

Melanie Avalon: Yes, we are on the same page. It's tricky because I just think that mindset is so so key, the way you described and the way I was describing it and I also want people to have agency and the freedom to fast if they want. And I think you can do both like you can fast to help yourself feel better from whatever happened. But it can just so quickly become judging yourself and restrictive and atoning and that's not what I think it should be about. Shall we go on to our next question?

Cynthia Thurlow: Absolutely.

Melanie Avalon: So, Deborah wants to know, "What about toothpaste?" Deborah says, "I in my window in the early evening but sometimes forget to brush right away, later I get ready for bed and need to brush. I use baking soda a lot, but once in a while Dr. Bronner's Peppermint paste, not lately because it's a flavoring. Is baking soda, okay? And okay. I'm excited about this conversation because, Cynthia, have we talked about toothpaste, you and I on the show?

Cynthia Thurlow: I think we have?

Melanie Avalon: We have?

Cynthia Thurlow: I do feel like we have.

Melanie Avalon: Well, I feel, because I know Gin and I have talked about a lot. I couldn't remember what you've said you brush your teeth with?

Cynthia Thurlow: Yeah, I use Primal Life Organics and I actually right now have the unflavored variety because my kids-- we were trying to get them onboard and they didn't love the powder as opposed to a paste. And so, I ended up taking it and using it. in regards to Deborah's question, unless you are swallowing your toothpaste, I don't want anyone listening to feel like they have to stress about brushing their teeth because we all need to do that and baking soda is fine. I think as long as you're not swallowing it like toddlers, when we have toddlers and we have to remind them to spit it out and not swallow it. I think you're completely okay. If you're using a cleaner product like Primal Life Organics as an example, we'll link up the affiliate code for that. They're completely clean products, there's no junk, there's no artificial anything, artificial sugars, etc., no fluoride, and we'll link up the podcast I did with Trina Felber, she's another advanced practice nurse who has kind of created this whole clean-mouth line, which I'm obsessed with and I think it's really fantastic. But with regard to Deborah's question, brush your teeth, spit out the toothpaste, and don't stress about it. That's my feeling, I think this is one of those things that should be no stress. It's like if you have to brush your teeth in your fasting window, no big deal. I do it all the time, totally fine. What do you think?

Melanie Avalon: I feel the same way. And it's interesting. I think toothpaste is one of the places where I can really see an evolution in my-- so, I use the word neurosis, it was one of the first things that I went through a period where I was like, "Oh, I have to make own. Order kaolin clay and mix it up myself." And I went from that to, I really don't stress about it as much anymore. I found a few that I really like. I was doing the tooth powders for a long time. I found them a little bit messy for me and I finally went back to tubed toothpaste and I actually use a few different ones. But if you want a tubed toothpaste, it doesn't have really any sweet flavor to it. Well, it is salt toothpaste. I love that toothpaste. It is so strong and it has no sweet flavor which is really hard to find. But I agree with Cynthia that-- I also love Primal Life Organics. So, that's a great plug. And we will put links in the show notes to that. But yes, I agree with Cynthia, don't stress about it, and baking soda is completely fine.

Cynthia Thurlow: Exactly.

Melanie Avalon: All right., shall we go on to our next question?

Cynthia Thurlow: Yes, this question is from Ann and the subject is, "Digestive enzymes." "I love listening to your podcast while I'm doing chores around the house. I only have 30 episodes left. I love this. I have a question about taking digestive enzymes. I had my gallbladder removed about 13 years ago. Ever since that I've dealt with stomach cramps and having to go to the bathroom after eating a heavy meal especially if it was the first meal of the day. Before my surgery, I had no stomach issues. I could literally eat anything anywhere anytime with no worries. I come to think that the stomach issues were just a normal side effect of the surgery and I just had to deal with them. However, I started talking to friends and family who have had their gallbladder removed and realized they did not deal with this problem like I do. I heard you mentioned digestive enzymes on the podcast and I did some research and decided to give them a try. I've been taking them for about a month and they've helped so much. I go to the bathroom like a normal person now and don't have to worry about stomach issues after eating."

Here's my question, "I've been doing intermittent fasting for a year. I do mostly OMAD with no restrictions. I've lost about 30 pounds. It has been slow, but I feel great and not restricted at all. I've never been able to stay on a diet this long and have even been on several vacations and I've been able to get back on track easily. About the time I started taking the enzymes my weight plateaued and I felt like I even gained a couple of pounds. My weight loss has yo-yoed up and down the whole time but not like this. I'm just wondering if the enzymes are helping me absorb fats that previously my body could not and that has something to do with the plateaus. I haven't changed my eating habits at all, I definitely don't want to stop taking the enzymes because of how much they have helped me, and I'm sure this is healthier for my body but I'm just curious, I would like to lose about 50 more pounds. Thank you so much for all the great information you provide" Ann.

Melanie Avalon: All right Ann, thank you for your question. I think this is a great question. I've thought about it more in regards to-- so I eat a lot of fruit as listeners know, like pounds of fruit every night and I've gone through different levels of taking digestive enzymes with it. At one point, I was taking barely any and then other times I've been taking a lot. I've noticed that when I take a lot and I take a fruit-- I get like no digestive issues from it. But it really breaks down the fruit like not to be TMI, but I can see the difference in my bowel movements from how it's affecting the fruit. And so, I've been concerned about the sugar release from that. I'm like am I actually turning the fruit into more like fruit juice in me because I'm breaking down the fiber with the digestive enzymes? I don't want to scare people away from digestive enzymes but I just wanted to speak how I have thought about the nuance of this. And to clarify, I tend to go really extreme.

So, I would take tons of digestive enzymes, I wouldn't be concerned about this if it was just like a very small or actually probably even normal dosing. And that said, I have also thought about this more in relation to Ann's question, probably historically, not so much with enzymes. But with people-- especially when I was really having a lot of GI issues and gut health, I would spend hours and hours and hours in Facebook groups about SIBO and IBS and things like this. And people would share stories about having leaky gut and having issues with their gut health, and then gaining weight from healing their gut. And presumably that's from absorbing more food, like absorbing more nutrients. So, I can completely see if you went from a state where you weren't really absorbing your food and then you're taking these enzymes, and now you are absorbing your food. Yeah, I could see how that would make your weight plateau and/or even gain depending on what you're eating which kind of comes back to what I feel like I always come back to on this show, which is-- the enzymes are working for you, that's great. I would keep using them, this is awesome. And you seem to be on that page.

If weight gain is a concern and even if it's not, I would mitigate that or address that with the actual food choices, which she doesn't mention. She just says that she hasn't changed her eating habits, but she hasn't mentioned what those are. So, that's what I would look to, "Oh, I got it, I do mostly one meal a day with no restrictions. Okay." So, it sounds like you're eating just-- if there are no restrictions, I'm guessing it could even be like standard American diet. If that's the case, there is so much potential here for A, both having wonderful and improved digestion with these enzymes and B, not plateauing and not gaining, maybe even losing weight by making some conscious decisions around the food that you are putting in your body. So, if there are no restrictions right now, I mean, you could just start it very basic, which would be shifting from just not having processed foods, so you don't have to worry about macros or even the types of foods but shifting to a whole foods-based diet. That could have a huge, huge impact on your-- not only your weight but your health in general. And then a lot of people in our audience already exist within that whole foods-type paradigm. And then that's when I think you can move to the next step of like a macro-based approach of like low carb or low fat for example. Yes, especially if you have 50 pounds to lose. Yeah, I would definitely look at the food choices, I would keep the enzymes, look at the food choices. What are your thoughts, Cynthia?

Cynthia Thurlow: That was a really comprehensive answer. It's interesting, in my patients that have had their gallbladders out, I typically have found tremendous success with ox bile or bile salts, that's usually a starting point for them versus digestive enzymes and a lot of that has to do is when your gallbladder is removed, you still produce bile, but it just drips all day long. So, most of my cholecystectomy patients, which is the fancy word for gallbladder removal-- most of them really struggle with either constipation or diarrhea. And if Ann is finding that she's feeling better on digestive enzymes, I would stick with what she's doing because she feels better. Yes, and I don't know Ann's age but we start absorbing less nutrients as we get older. That's why we actually need more protein as middle-aged people, so Ann could be young, but I'm guessing she's probably at least middle aged just based on the fact the way she's describing things. The other thing I think about is OMAD and weight plateaus. I started thinking about the fact that your body might have just gotten to a point where with just only one meal a day you're not getting enough macros in, you may need to change things up. I always say when you hit a plateau, it's time to change things up either tracking your macros to see very clearly how much protein you're eating a day. Are you overeating fats? Are you eating too many carbs? How's your sleep? How's your stress management? Are you lifting weights? As people start losing weight, sometimes they want to get more physically active. Do you take walks? Where are you in your menstrual cycle? Or are you no longer menstruating? Those kinds of things are very helpful. But I would say shaking things up is going to be very important. And then, giving consideration, most of my patients with a cholecystectomy really benefit from ox bile or bile salts. These are supplements you can get over the counter. And those have been hugely impactful.

Melanie Avalon: Oh, by the way, have you ever taken, Cynthia, ox bile or anything like that?

Cynthia Thurlow: I have, I tend to be-- I think probably the listeners know that in 2018, I got the worst food poisoning in my life in Morocco, picked up a parasite and then ended up six months later having a 13-day hospitalization. So, my gut has really been ravaged over the last several years. And I've been told by my providers that I've had episodes of fat malabsorption, so have I ever taken it? Yes. What we've kind of worked on is artichoke, artichoke extract is actually a little more gentle than traditional digestive enzymes. And the more I've learned, the more I understand that there's so much bio-individuality, you may be able to take a really strong digestive enzyme, which for me would just not work. And so, there's a little bit of give and take, but yes, I have tried ox bile and bile salts, I do and have had episodically. I'm not someone that tolerates like a lot of animal fat. So, lean meat I do much better with and I think my gut microbiome really took a massive hit in 2018 into 2019. So, I'm definitely very carefully navigating what I add in to support digestion. How about you? Have you tried it?

Melanie Avalon: I went through a period where I was using it like you, I favor lean meat, so I didn't really see the need for it specifically not being on as high of a high-fat diet. I'm glad you brought up the individuality with digestive enzymes. This is a very vague teaser, but I think after we get out the next few supplements that we have, I have a really big supplement idea, project that I want to do that's going to relate to bio-individuality with digestive enzymes, I think it's probably going to be my big supplement project of 2023. So, people get excited. So yeah, but it's so true because especially with the digestive enzymes because goodness knows I have tried so many different ones and it really is about finding the one that works for you and that suits your personal digestion.

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Melanie Avalon: Related to digestion. We have a question from Alyssa. She says, "IF and digestive changes." And Alyssa says, "I am new to IF, about three weeks in doing a 17-7 window and I have never had any sensitivities to food. I have found since starting IF my stomach has become sensitive, as soon as I open my eating window and start eating, I find myself nauseous and bloated. I have experimented with many different types of foods, tried eliminating different food groups to see what is triggering this, and always have the same outcome. I've also had increased problems with loose bowel movements since starting IF. I'm wondering if my body is just taking longer to get used to this new eating pattern and if this is a common finding among new IFers. I definitely want to make this a lifestyle as I've researched and researched and I found nothing but good information. But the stomach issues are such a turn off. I think I've lost a little weight, but at this point, I really just want to get a handle on the way I feel and focus on weight loss as a secondary concern. I have about 25 pounds to lose but I did lose 40 before discovering IF, but hit a plateau for several months. I'm 29.5 not willing to claim 30 just yet female and have two kids, ages 1 and 2, if that information means anything to you." So, continuing the digestive issue conversation. Thoughts?

Cynthia Thurlow: Alyssa? Well, I think that there's obviously something going on, I would start with lighter foods, try some bone broth to break a fast, I would have a light salad, I would gauge to see if it's certain types of foods that are exacerbating your loose stools. I actually had a really good podcast with Megan Ramos and we kind of talked about troubleshooting some of these issues. And I just find that breaking the fast with a lighter meal or backing off on fasting entirely, you're talking about a 17-7, maybe especially as a 29-year-old female, you shouldn't be fasting right before your menstrual cycle. I would really try to give yourself a solid week in your follicular phase, which is after your bleed week and see how you feel, trying a little more protein, not doing as much uncooked vegetables, light, light, light stuff and see how you feel.

Melanie Avalon: Yeah, something that I'm focusing in on is the fact that she said she'd never had sensitivities to food and now she does. And I think so-- this actually could be very helpful, it could be a flashlight situation. It's possible that you were having inflammatory reactions to food, but you just weren't realizing it until IF kind of like paved the way for you to have that moment where you actually saw how your body was reacting to food, which I think a lot of people do experience that, which is a good thing. I think. So, I love Cynthia's suggestion, definitely check out that episode with Megan Ramos. I'd be curious-- you said you've tried many different types of foods and you've tried eliminating different food groups. I'd be curious the extent to which you have tried A, elimination protocol as like an actual protocol because I've interviewed a lot of people who talk about elimination diets to solve these issues and a consistent theme with all of them. I'm thinking of like Dr. Will Cole, I'm thinking of Dr. Peter Kozlowski, I'm sure quite a few others.

A consistent theme is like really doing it properly, like actually committing to this short-term elimination diet rather than just kind of like, casually, like eliminating one thing here, because there-- Well A, the effects of food could probably last up to three days as far as just like, for some people the transit time and just the effects from that food. So, if it's a casual approach to eliminate things, you might not be able to see a difference if you just eliminate one thing one night and see how you react and there are so many factors involved. I think taking a conscious approach to an elimination diet might be helpful, but is possible that your body is still adjusting because it has been about three weeks. I would love to hear if things have changed. But yes, yes, yes, yes. I do think a lot of people do experience this. And there's a lot of potential to find the answer. And so, something that might be a game changer. This is something that I'm definitely, definitely, definitely going to make my own version up in the future because it's something that when I go through issues, especially with feeling like my stomach is sensitive and reacting to foods, like right when eating, there are different blends that involve L-glutamine and when taken on an empty stomach it can really help rapidly heal the gut. Particularly L-glutamine, as well as DGL which is, I don't even know how you say it, deglycyrrhizinated licorice extract. So, the one I take right now and I have got to make a version of this, it is shocking how much it helps me. I would love to hear Alyssa if you take this if this really, really, helps you. So, it's called Gut Assist. It's by Dr. Danielle, you can get on Amazon, I'll put a link to it in the show notes. Like right now it has 6337 reviews and 4.5 stars. So, it is a combination of L-glutamine of something called arabinogalactan, and then that DGL as well as some aloe vera. I would definitely, definitely try that. And then also stay tuned because I'm definitely going to make my own in the future. So, if you want to get updates about that, you can go to avalonx.us/emaillist. And you can also text AvalonX to 877-861-8318. That will get you text updates as well as a 20% off coupon code. So definitely check that out. Okay. Any other thoughts from you, Cynthia?

Cynthia Thurlow: No, I think you did a great job.

Melanie Avalon: You as well. Well, this has been absolutely wonderful. So, a few things for listeners before we go. If you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. The show notes for today's episode will be at ifpodcast.com/episode290. Those show notes will have a full transcript, so definitely check that out. And you can follow us on Instagram, we are @ifpodcast, I am @melanieavalon, Cynthia is @cynthia_thurlow_ and I think that is all things. Anything from you before we go?

Cynthia Thurlow: No, this has been fantastic as always.

Melanie Avalon: I agree and keep the good questions coming and we will talk to everybody next week.

Thank you so much for listening to The Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice, and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team, administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and re-composed by Steve Saunders. See you next week.

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Jul 17

Episode 274: Fasting On Vacation, Chocolate, Menopause, Ovulation, Hypothalamus, Nulliparous Women, Magnesium, And More!

Intermittent Fasting

Welcome to Episode 274 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

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SHOW NOTES

LMNT: For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase! Learn All About Electrolytes In Episode 237 - Our Interview With Robb Wolf!

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The Melanie Avalon Biohacking Podcast Episode #117 - Tim Spector

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Listener Q&A: Deanna - IF and the aging menstrual cycle

Ep. 206 Pt 1: A Deep Dive into Perimenopause - Hormonal Imbalances and Birth Control with Dr. Tabatha Barber

Ep. 212 Pt. 2: A Deep Dive into Hormonal Imbalances and Menopause with Dr. Tabatha Barber

Menstrual cycle variability and the perimenopause

#76 Stuart Phillips, PhD, on Building Muscle with Resistance Exercise and Reassessing Protein Intake

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Listener Q&A: Monica - Magnesium Question

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Ep. 194 – The Toxic Truth About GMOs

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 274 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time and get ready for The Intermittent Fasting Podcast.

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And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting, it's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup maybe playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That's because ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years. 

Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means, when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life and their makeup is amazing. Check on my Instagram to see what it looks like. Tina Fey, even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well. 

And lastly, if you're thinking of making Clean Beauty and Safe Skincare, a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It's like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show.

Melanie Avalon: Hi, everybody and welcome. This is Episode number 274 of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with, Cynthia Thurlow.

Cynthia Thurlow: Hey, there.

Melanie Avalon: How was your trip?

Cynthia Thurlow: Amazing. I think that's the best, the best way I can describe it. I think on a lot of levels that far too many of us don't take breaks from work. For me, I was really, the entire time during the book launch, I kept saying to myself, “If I can get till June 15th, if I can just get to June 15th, then as soon as I got on that plane, I was so ready to disconnect and spend time with my family” and it was absolutely perfect. We had great weather, we ate amazing food, we saw amazing things, we had a lot of togetherness. I'm sure the teenagers would say that they loved it, too, even though, there was a lot of togetherness and a lot of disconnection from their electronics because we didn't allow them to have an international plan on their phones, which I thought was the best decision ever.

Melanie Avalon: My family is actually in Europe right now and they did get a plan. It's so funny how things have changed because I remember when they would go to Europe years ago, now, it just feels the exact same as them being here in the US with the international plan.

Cynthia Thurlow: I didn't even have an international plan. That was my decision that I really did not want to be that accessible. My husband has an international plan. So, I kept saying, “You know what, anyone that was, the dog sitters, the house sitters, anyone that needed to reach us, they could reach my husband, but I only had Wi-Fi in my hotel.” And so, it was wonderful.

Melanie Avalon: That's so nice. What was the highlight of the touring and everything that you saw? 

Cynthia Thurlow: Oh, I think Prague. We started our journey in the Czech Republic. We as a family have all said the same thing that Prague absolutely blew our minds like everything about it. The fact that we just really explored every square inch of the city, and we're able to do a laundry list of things, the kids had prioritized, and my youngest has been learning German, and so, he's been really interested in going to Eastern Europe, and he identified very specifically as is his personality. things he wanted to do, and so, we hit all the things that everyone wanted to do, and just really enjoyed the culture, and the people, and whether or not listeners know this about me or not. My first undergraduate degree was in international studies. I had a foreign affairs degree and I was all pre-law and undergrad, and gotten into law school and didn't go. But here's the big thing. I was in college when the Berlin Wall came down. I was in college when Eastern Bloc countries really started to dismantle. And to actually be there, and to be able to ask people what it was like to live under communist rule, and what it was like when the Soviets occupied a lot of these countries, for me being a gigantic international studies nerd, it just-- My kids were so embarrassed like, “Please don't tell another person that you were in college, when the Berlin Wall came down.” They were so embarrassed. But for me, I just savored every bit of it and love the people. 

When you think about just the influence on architecture and the hardships that people have really grown up with, I found everyone in Prague to just be so gracious, and humble, and interested. Another thing that really impressed me was the support for those in the Ukraine throughout Eastern Europe. Everyone was happy to take in the refugees and there were a lot of demonstrations, very peaceful ones. But for me, I would say probably, Prague. I was really surprised. It's a very, very special place for all of us and I think it's really cool that my kids got to see so much history during this trip, not just in the Czech Republic, but throughout Eastern Europe. 

Melanie Avalon: Here's a question for you related to the show, because Gin and I used to discuss this a lot. So, how do you change or how do you adapt to your fasting and eating windows when you travel?

Cynthia Thurlow: Yeah, it's a question I got so often that I just didn't ask me anything on Instagram, because I was like, “Thank you for the 500 questions I've gotten in my DMs.” I adopt a more relaxed pattern. And so, it may be that I have a wider feeding window, I may do a longer fast, I definitely had days where I really wanted to travel and savor the foods of where we were traveling to. I might have had something around breakfast time, I might have eaten something midday, I might have had a dinner. I would say, I allotted a lot of flexibility. We did a lot of walking. We were very physically active. So, I wasn't worried if I was consuming more food because I know for myself personally. It isn't dessert unless it's chocolate and there's just not a lot of chocolate there. For me, there wasn't the temptation of having dessert. It was more-- one place or we traveled to, they would make me gluten free bread, which I then felt obligated to eat, which I then slathered a lot of butter on. And so, I just savored the fact that I was on vacation.

The honest answer is everything was a little different each day, I definitely had some days where I would have-- there might have been a day where I eat more than I normally did. The next day I might have just fasted longer. The thing that I found most humorous was obviously, I've teenage boys. So, they ate voluminous amounts of food 24/7. I would sit down and try to explain to a waiter or waitstaff that I wasn't eating, they were like, “Are you sick, are you on a diet?” And so, finally, it just said, “No, I intermittent fast” and they're like, “What is that?” That was a very easy way to make conversation with people, but I just leaned into my body, I made sure I hit those protein macros more often than I asked for extra protein. Anytime there was a steak served, I always asked for a bigger piece of steak, which they were humored to say they're like, “You really want more steak?” I was like, “More steak.” 

I think the message I would send to our community is to just be open, to not being so strict on vacation. To me, I just enjoyed eating foods I don't normally eat and then not stressing about it, because I was doing so much walking and I knew I could just augment what I was doing very easily. The next day, it's like, “Okay, yesterday, I had gluten free bread twice. Am I going to beat myself up? Absolutely not. Am I going to make sure I fast maybe a little bit longer today and then I really lean into those non-starchy veggies and lots of protein? Absolutely.” I came back from vacation. I have not weighed myself, but my clothes fit the way they did before I left for vacation. And so, from my perspective, it was a win-win without feeling any sense of guilt. Having a conversation with my kids all along the way. They think I'm weird anyway that need as much food as they do. But just encouraging them, “Try something new, I tried lots of new food,” and I definitely felt it was the perfect balance of having fun, hitting most of my macros most days because I can conventionally, visually evaluate like, “Did I hit my protein macros,” and then just enjoying the rest, and not being super strict.

But I might be one of those people that's just unusual or odd that I've never been someone like I go on vacation. I blow the Mother Lode on my nutrition because I just don't feel good and it's more important to me that I sleep well and I feel good then it is that I eat something that I know isn't going to agree with me. So, it's easy to avoid those kinds of things. For me, those kinds of foods are generally alcohol and a lot of sweets. In Eastern Europe, there just aren't a lot of sweets, at least, not where we were. If they did, it was more like bread sweets, which just isn't really my thing anyway. But if they had showed me a lot of chocolate and I did indulge in some chocolate in Vienna, there was this amazing chocolatier that was there and we got some tiny truffles, but they were delicious and I was like, “That was worth it.” But beyond that, unless it's chocolate, it's not dessert in my mind.

Melanie Avalon: Well, first of all, for me for traveling, I haven't traveled that much recently. But the one thing I used to dread before adopting a Whole Foods type lifestyle and intermittent fasting, I would be the type that would just go crazy with all the food and everything. Now, I remember feeling so happy once I found a dietary approach that I genuinely-- I love the foods that I eat, and I can still eat the way I eat at restaurants and such and still enjoy it to the same extent that I would have before with the way I used eat. I'm super grateful that-- It gets rid of the one stress I had surrounding traveling, which was just going off the rails with diet, because now, I just keep doing what I'm doing with the jet lag and such. Have you ever used fasting to align your circadian rhythm with the new time zone?

Cynthia Thurlow: Yeah, I definitely do that. In fact, I'm the person on the plane that never eats. [laughs] 

Melanie Avalon: You and me both.

Cynthia Thurlow: Yeah, I don't eat on the plane and I have to always just explain to-- Yes, I know. They ordered me a gluten free and dairy free meat. Yes, I know that they did. I won't eat it. Thank you very much. And then they just look at me like I have two heads, but I just find that I do a whole lot better especially if I'm not sleeping well on the plane. I didn't on the way to Prague and we had a two hour-- It's not worth boring the listeners with the two-hour ground delay we had. We were on the plane, and there was some maintenance form that hadn't been properly signed, and so, we had to go back to the gate, so, it ended up being a 10-hour flight. By the time that we touched down in Prague, I hadn't slept much at all. I always credit hydration electrolytes and fasting for helping me get pretty quickly on schedule. And so, for me, it's just one less thing to worry about. 

Then I'm not dealing with eating food that is not going to agree with me, although I always travel with Paleovalley beef jerky and salted macadamia nuts, and a little bit of dark chocolate. Those are things I typically travel with. If I were exhausted and starving, I could have something. But I do think that utilization of fasting as an adjunct to improving jet lag, I think I really credit it with being able to travel as much as we do and feeling-- When I hit the ground, I don't have the degree of jetlag I used to have when I was younger, which you would think would be completely the opposite seeing as I'm now older, but I think a lot of it has to do with the fact that the circadian biology, it's get light exposure, get hydrated, get yourself moving. We did a lot of walking on the first day in Prague, a lot. I really credit that with everyone being able to get on that schedule, 26 hours ahead of me, it's manageable, but not feeling quite as jetlagged as we could have been. 

Melanie Avalon: I think it's such a valuable hack that a lot of people don't realize and there's actually been studies on it. They've studied using fasting. I'm trying to remember-- It's been a while since I read it, but there was one on jetlag and using fasting patterns to basically alleviate those symptoms, because like you said, they are such a-- What's the word? Zeitgeist? Oh, no, no, zeitgeber, so basically something that informs your body of the time. [chuckles] You can travel, and essentially adopt the pattern you would have had in your normal time zone, and it can sink your body to the new time zone. If I'm just traveling, because when I was in California, I would often travel back and forth between Eastern time zone and Pacific, and that's not a huge difference, but there was zero issue with switching back and forth. Continental travel for me is no issue, because I just always stick to my window which is an evening dinner and I just basically reset my body wherever I go.

Cynthia Thurlow: Yeah, the fasting longer piece is usually how I do that. I'll be in Austin in a couple days and I already know-- I’ve an early morning flight, I'll land there at 12, and my plan is to get off my flight. I know exactly where I want to go for lunch. I'm going to have a big lunch, and I'll you know break my fast which will probably be fairly long, almost probably I would guess closer to 24 hours at that point, but I'll break my fast, so that I'll get as quickly as I can, because if you look at conventional research on changing time zones, you need one day per hour of difference, where is time for that. I don't have time for that. I know you don't have time for that. And so, I do all the things to make sure I try my hardest to buffer those time differences as quickly as possible. But I love that you even at your stage, you're able to go back and forth to the West Coast and then just keep that consistency with your meal timing.

Melanie Avalon: Yeah, it was literally no issue doing that for me. You mentioned that when you were in Prague and such, people would look at you strange with the fasting, so, did you find that--? Because now in the US, I feel fasting is a known thing, intermittent fasting is. Did you find it wasn't as much of a thing there?

Cynthia Thurlow: No. I think it has a lot to do with Europeans overall. They eat smaller portions. They don't understand-- You ate last night, but now, you're not hungry at all. You're hungry, but you're not going to eat. And so, just trying to explain to them that this is not a diet. This is a lifestyle. I do this, so that I can enjoy all the other things I eat in my feeding window and so, I definitely felt I had a lot of conversations, although, ironically, for part of our trip we were on a ship, there was a very large table of Americans sitting next to us, and I heard a woman say, “Oh, yeah, I've been using this new strategy. It's intermittent fasting.” And so, I heard that, my whole table, my kids and my husband, their ears perked up. I was humored to listen to her talk about this. She was probably a woman in a different life stage than I am, but she was talking about it very openly and saying, this is how she has been able to fuel her lifestyle and feels good. She was explaining it to the waitstaff as well. And so, I feel I was probably not the only one that talked to them about that. But they were fascinated. They're like, “You choose not to eat, even though you could.” I was like, “Yes.” They're fascinating.

Melanie Avalon: This is something I haven't looked up. I wonder if there are any other countries that-- I feel it's well known in the UK because we have a lot of UK listeners and Canada. I wonder if there are any other countries that practice this as a lifestyle more and more. 

Cynthia Thurlow: What's interesting is, a lot of the Eastern European countries we were in are predominantly Roman Catholic, at least based on the guides that we had, discussions that we had. And so, a lot of the major religions, it's an aspect of practicing their religion. I would imagine that there's probably some degree of fasting, although it's probably more related to high holy days as opposed to something people are doing ritualistically every day. But I can tell you that when I talked about fasting with people who are curious, they were like, “Wow.” But what's interesting to me consistently and I was in five different countries, people were much more active and it could have also been that we were closer to cities and where people are just more active to begin with. But I didn't see the amount of obesity we have here in the States. People were very active, portions were small, certain countries, there's a lot more smoking, but people were just more focused on enjoying lives. They're enjoying their lives. They don't work the same hours that Americans do. I think that there's a lot more savoring experiences in their lifestyle. And of course, this is a gross generality. I was not in every square inch of each one of those five countries, but just my general observations, being a tourist, I was really pleasantly surprised to see that.

Melanie Avalon: And speaking to the religious piece, I'm actually currently reading-- It's funny. I thought I had read the book, but I actually haven't. It's Jason Fung and Megan Ramos’ Life in the Fasting Lane. So, I'm enjoying that book. But I think it's in that book, they were saying, they made the case that every single major religion has fasting in it. I was like, “hmm.”

Cynthia Thurlow: It really does. It's interesting that when people try to, “Oh, it’s new and novel.” No, it's not. [laughs] It dates back to Biblical times, people and beyond.

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When you wear a continuous glucose monitor, which is painless to put on, I promise, I have a lot of videos on my Instagram of how to put them on. So, definitely check those out. It gives you a picture of your blood glucose levels 24/7 for 14 days. What I love about the NutriSense CGM program is, it has a super awesome app that helps you interpret the data and really understand what's going on. In the app, not only does it track your data, but you can log meals, see macronutrient breakdowns, and so much more. It even gives you an overall score for each of your meals based on your body's response, so you can really find what meals are working for you. Each subscription plan includes one month of free support from a registered dietitian. NutriSense dieticians will actually help you identify what you should be paying attention to, what that data actually means. They can really hold your hand if you're new to the space or if you're already knowledgeable, then they can provide you even more advanced tips and recommendations. They'll make sure that you adjust your diet and lifestyle to find what you enjoy doing, so that you can have long-term sustainable changes. NutriSense also has a private Facebook group for members, where you can find support from other members and learn about their experience. I love wearing a CGM. I just think it is so profound. Even if you just do it once for 14 days, I think you will learn so, so much. But then, of course, lasting sustainable change can take time. Getting a longer-term subscription can be an amazing option to consider. 

NutriSense has six and 12-month subscriptions and those are cheaper per month allowing you to not only achieve your health goals, but also ensure that you stick to your new healthy lifestyle for the long term. It's helped me realize for example, how low carb versus low fat affect my blood sugar levels, how berberine has an amazing effect at lowering my blood sugar, and so much more. You can get $30 off any subscription to a NutriSense CGM program. Just go to nutrisense.io/ifpodcast and use the coupon code, IFPODCAST for $30 off. That's N-U-T-R-I-S-E-N-S-E dot I-O slash IFPODCAST with the coupon code, IFPODCAST for $30 off any subscription to a CGM program. There's a reason Cynthia and I talk about CGMs all the time. We love them. NutriSense is giving you guys’ access to them. So, definitely check this out. And we'll put all this information in the show notes. All right, now back to the show. 

Melanie Avalon: Last question. So, you're a chocolate person?

Cynthia Thurlow: I'm absolutely a dark chocolate aficionado snob/patron. Love it. It's my one like vice. It's the one thing my husband will say to my kids, “Don't touch anything of your mother's as it pertains to chocolate without asking her first.” I'm always like, “It's the only thing in the house that's mine.”

Melanie Avalon: That's my mom, too. I'm fascinated why there's a dichotomy between chocolate and vanilla. Why? Because that must just be cultural. It's not they're opposites in their compounds inside of them, but I am very much a vanilla person.

Cynthia Thurlow: I like vanilla, but I love chocolate.

Melanie Avalon: I like chocolate, but I don't crave chocolate ever. I think I have once and I was like, “What does this mean?”

Cynthia Thurlow: [laughs] Well, that's why we say to people, when our waiters would always offer dessert options, I was like, “No, I'm good.” They were always like, “We don't understand.” I said, “Unless, it's chocolate, it's not dessert.” That's my mentality. I've been that way my whole life. It's not even a chocolate cookie, chocolate cake, it's like, “Give me a piece of chocolate and my life is good.” That is my mentality. Whereas my kids and my husband, if you give them ice cream, they don't need anything fancy. They would just love some ice cream. And so, I think each one of us in our minds designate. For me, it's not a craving. It's a polyphenol rich substance that if used appropriately is something that can be beneficial to your lifestyle. But for me, I'm not eating a Hershey's chocolate bar. I don't even like that kind of chocolate. I am a purveyor of higher end dark chocolate, and I just have a little bit, and I'm so happy. In a pinch, I might have some stevia sweetened dark chocolate in a pinch. However, that chocolatier in Vienna, oh, my gosh. I even took photos, I took videos, it's all in my fasting stories, little thing for Austria. Yeah, for me, those are moments that make me so happy. Something really simple like that. I don't have to make it complicated, it doesn't need to be Black Forest Cake or some type of intricate latticework on a pie. Nope, just give me a piece of dark chocolate and I'm happy and very simple.

Melanie Avalon: I know listeners know exactly what my equivalent is to that. Do you know what mine is?

Cynthia Thurlow: No, I don't. You have to tell me. 

Melanie Avalon: Funfetti cake.

Cynthia Thurlow: Really? 

Melanie Avalon: Yes.

Cynthia Thurlow: That's--. Is it the moistness, is it the little sprinkles?

Melanie Avalon: There's some chemical they have that just speaks to my brain. But yeah, the Funfetti cake, so any birthday cake with the Funfetti flair to it, it used to be a running thing on the show because I hadn't had it since changing my diet. Gin was insistent that if I were to have it now, I wouldn't like it anymore and I was like, “No, you don't understand.” [laughs] It will taste amazing. And then finally I tried. They have a gluten free version. So, it wasn't even the original and it was the most fantastic thing. Oh, here's a question. Did you do ZOE, the muffins?

Cynthia Thurlow: It's still in my freezer and my husband is so mad at me because we just had a colleague of mine, they have a cow share, and they had too much meat. They gave us part of their cow share, which means our freezer is completely packed with grass-fed meat and my husband's like, “Please get rid of these.” I was like, “I promise I'm going to do them” and he's like, “You've been telling me that for three months.” “No, I need to do it. It's embarrassing.” I'm saying this to the entire IF Podcast community. I will be doing that the month of July. I will be doing it. It's some two-day, one-day interval. It's coming up.

Melanie Avalon: I'm very excited to hear your experience and lot to talk about it on the show. I have a theory about it, though, and I polled my audience, and my polling confirmed my theory, which is that the muffins, people will talk about how they're the worst tasting thing. I was looking at the ingredient list before doing it. Again, it's something Gin and I would talk about and I was like, “I'm going to love these muffins.” I can just tell. These muffins are going to taste like heaven and they did because this was the first time eating a sugar fat process combination and probably, I don't even know how many years. It was literally, I saw my brain light up. It felt like a drug to me. And then I pulled in my Facebook group and I asked, “Did you like the muffins?” There were four options. It was like, I liked the muffins and I don't normally eat processed foods, I like them and I do eat processed foods, I don't like them and I—So, every combination of that. Basically, the people who don't normally eat processed foods liked the muffins and people who do, do not.

Cynthia Thurlow: I'll be interested. I'm not a vanilla cake person. Here again, you can see, there has not been this desire to eat said muffins, but I'm like, “I have it, I'm going to do it. I'm probably going to have a love-hate experience with this,” because three muffins is a lot. I was like, “How am I going to eat all that, especially because they're not chocolate?”

Melanie Avalon: I was like, “This is going to be a breeze.” I was licking the foil, I was like, [chuckles] “I need more.” Because then there's this miserable period where you can't eat for so many-- For listeners, I'm just assuming listeners know what ZOE is because we talk about it all the time on the show, but it's a program created by Tim Spector, who I've had on Melanie Avalon Biohacking Podcast, if you want to listen to that episode. Have you interviewed him?

Cynthia Thurlow: I have not. The reason why I have not is because I think I literally went through-- I got them and then I had that whole histamine response, head to toe hives after being treated for Candida and parasites. And so, then that put the kibosh on doing anything. I explained to them, I was like, “I had three days of systemic hives, something's amok.” And so, that got stabilized and then I had surgery, and I was not-- Because you can't exercise when you eat those things. I was like, “There's no way I'm eating this and then being completely sedentary.” I've just had a million excuses, which I didn't mean to make excuses. It's just been a couple of things have happened that I've not been able to do it sooner, but it is on my to do list, it will happen in the month of July. So, I haven't had them on yet, because I haven't done the testing. I had to explain to his assistant very nicely, I was like, “I am so sorry. It will happen this summer and then we'll get him on in the fall.”

Melanie Avalon: I really, really think his work is very nuanced. He's very plant based and everything, but he just does a really nice-- really, at least from my perspective approaching as unbiased as you can be analysis of the literature. His chapter on wine and alcohol was-- It's the first time I've read somebody basically-- He talks about the role of wine, and alcohol, and health, and he literally says in the book that and this is very controversial. So, I don't even want to say it. But even with pregnancy, it's probably not as much of an issue as people think. But in any case, so, for listeners, what the program is, it's these muffins that you have, and you wear a CGM, they provide you with the CGM, and it evaluates how your body processes sugars and fats, you also do a gut microbiome test, then it gives you a personalized interpretation of how you basically handle food, and what foods you should be eating. I think I have a code for that. Had they given you a code yet?

Cynthia Thurlow: I'm the slacker that they're waiting on me to get my act together. So, I will eventually have a code.

Melanie Avalon: My code is MELANIEAVALON10, yours will probably be CYNTHIATHURLOW10, because I think that's the format they use. One last thing about it, though, that's funny is, so, when I looked at how you have to do it, because basically the first day you eat these muffins, and then I think you have to wait four or five hours. For me, they were a miserable four or five hours because you basically eat something that just spikes your blood sugar, and then you have to fast. It's so hard. I was like, “This is what it's like to not be adapted to fast, to live in the blood sugar swinging state.

Cynthia Thurlow: Eating a Standard American Diet. 

Melanie Avalon: Yeah. Mm-hmm. I was like, “This is what this feels like.” It gave me empathy for people who haven't experienced the ease of fasting yet because I'm like, “This is probably what they're thinking fasting would be,” which is just really unpleasant. If you do a dinner only eating window like me, you can still hack it. I started it at, I don't even know what I did. I timed it so that I still could eat my dinner pretty late, and still have the muffin, and all be within the evening window. I think I was eating at 2 AM.

Cynthia Thurlow: Yeah, for me, because I am so protein centric, the thought of having something that I know is going to dysregulate my blood sugar so substantially, which has not been-- The N of 1 experiment has not been the one I've been looking forward to doing. I'm like, “Okay, this is not going to make me feel good.” Years ago, before I started putting two and two together as a perimenopausal woman, I would say to my husband-- Sometimes, we would have these dinner parties, and we would all eat good food, and then you'd have, I don't know-- Back in the day, when I could get away with eating a little more dessert and having a little more alcohol or having any alcohol, and then I would want to take a nap, and I didn't realize because my blood sugar had crashed, I was like, “That's just not a good feeling.” And so, I'm going to think optimistically that I'm going to be able to weather whatever happens. But for me personally, as much like you do, I think because we eat such a nutrient dense Whole Foods diet and keep our blood sugar really within a very healthy range, those extremes don't make you feel good. And so, I need to just rip off the band-aid and do it.

Melanie Avalon: I was so apprehensive about doing it. What I do recommend is planning it out, so that in that time following it, you have an activity, something very distracting. Actually, a fun fact they might have changed this. I feel I probably drove them crazy. I was asking them, because they have really amazing customer service and the app when you're doing it, and you can message and ask a lot of questions, and I asked so many questions. You technically, at least when I did it don't have to do day two of the muffins. Just a little fun fact.

Cynthia Thurlow: Oh, I'll have to check that out because I have a package of three and a package of two, and I just kept saying, “God.”

Melanie Avalon: Yeah. At least when I did it day two, it did not inform your personal results. It only informed their data collection. So, I was like, “Well, if it's not affecting me, I don't know if I'm going to--" But then actually, I did end up doing it because they were so delicious and I was like, “I want to repeat this experience.”

Cynthia Thurlow: Your fun Funfetti ZOE, that's hilarious. 

Melanie Avalon: Yeah, So, for listeners, we'll put a link to everything that we talked about in the show notes. Okay, shall we answer some listener questions?

Cynthia Thurlow: Absolutely. 

Melanie Avalon: All right. To start things off, we have a question from Deanna and the subject is: “IF and the aging menstrual cycle.” And Deanna says, “Hi, I have tried to search for answers on this. I googled, but I'm not finding any info from actual IF-ers. Only what Western medicine has to say. I've been doing IF for about three months. I started in February. I was really surprised at how simple it was right from the start. I thought, “Wow, I have finally found something that works” is totally doable and actually sustainable. Yay! I have been clean fasting since day three, which is when I learned what it was. Even the black coffee was a fairly easy transition. I originally thought it would be totally impossible and wasn't even going to try it, but I did and now, I crave my black coffee. I'm still amazed. That was one month-- One month ago, I experienced some cramping and a very short spell of bleeding. It stopped after a couple of days and it wasn't heavy at all, it was somewhere between spotting and light. But now, a few days ago, cramping again. Nothing sharp, but dull and constant, and the bleeding started again, but heavier this time around, also a longer duration for days so far. 

I thought maybe I'd worked too hard. I raked and burned leaves all day, Saturday and Sunday for 15 hours. I'm 52 years old. I had an IUD placed in January of 2018. I stopped getting a period entirely early mid-2020, which was awesome. I was told at the time of the IUD that I was in perimenopause and that by the time it would need to be removed, it's a five-year thing. I would likely be in menopause and would probably not have a period anymore. What are your thoughts about my resurrected period? I’ve a doctor appointment this week, it's about something else entirely, but I will bring this up. I'm just afraid the doctor will poo-poo my IF lifestyle. I feel IF has to be a part of what's happening, but I was hoping it was just making me age and reverse. Ha, ha, could that be true? I think it sounds reasonable. I would love to hear what you think about all of this. I know I can't possibly be the only one that has had this issue, but I asked in my IF Facebook group, and everyone thought it was really odd, they had never heard of such a thing, and they all told me to contact my doctor. I'll be watching for podcasts about this, but if you don't, no worries, I'll keep reading and searching for answers. Thank you for your time, Deanna.” So, this is a fun, interesting question.

Cynthia Thurlow: Yeah. Well, I have multiple thoughts. Deanna, thank you for your question. Being 52 years of age, here in the United States, the average age of menopause is 51. When your doctor placed, I presume a progesterone-related IUD, intrauterine device. You mentioned that you went two years without any bleeding, whether or not that is a byproduct of the IUD, I'm not sure. Could that have been menopause already? Not sure. And then you started having more bleeding. There's a lot of anecdotal evidence about women. When they start fasting, sometimes, they may get changes in their menstrual cycle either lighter, heavier, more frequently, less frequently, and I always give women the advice that to weather whatever is happening, meaning it could be your body, just finding a way to recalibrate hormones in a healthy way. Really the only way to know where you are and at 52, you're very close to menopause. What we typically end up seeing is, as women are at the tail end of perimenopause, for anyone's listening, 10 to 15 years preceding menopause starts in your mid-30s, mid to late 30s, you're there, and this is when we start to get this drop off on progesterone. We get some relative estrogen dominance. 

Women can have very different experiences in perimenopause. Some people breeze through it very easily, others really struggle through a variety of reasons. When you see your doctor, I would absolutely identify that you hadn't had any type of bleeding or cycles in about two years and whether or not that's a byproduct of the IUD. I'm not 100% certain. I have plenty of patients that don't get menstrual cycles while they're on the IUD. I have others that do sometimes have some ovulatory discomfort, although the closer you get to menopause, you're not ovulating every month. Could this have just been a quirky ovulatory period? Absolutely. But your doctor needs to run some labs. I actually have done quite a few podcasts on these kinds of topics. If you're not a listener of Everyday Wellness, most recently, I did two podcasts with Dr. Tabatha Barber. She's called The Gutsy Gynecologist. She's absolutely lovely. We talked about topics just like this. How do we find out where we are in perimenopause, are we in menopause, what's going on? The IUD is just a band -aid, so it can really mask knowing when that transitional period has occurred. They can draw an FSH, a follicular stimulating hormone, typically that needs to be drawn at least on two separate occasions. This is communication between the brain ovaries. And typically, when it's greater than 40 on two separate occasions, that can be a sign. It's not definitive that you are very close to menopause.

You can look at a DUTCH, a dried urine and saliva test and I've done a lot of podcasts with different experts talking about the DUTCH and the validity of that. But I think this is just one of those times where as your body is getting better balance, you're probably getting more insulin sensitivity, probably getting a little bit better balanced with your sex hormones, and better appetite regulation. You may see some changes in your menstrual cycle, but this is one of those vague questions. Meaning not that you haven't given enough information, it's just we need more information to be able to provide additional insights. But I would say Dr. Tabatha was a recent favorite. I actually did a podcast with Dr. Sara Gottfried recently. But if you do a Google search on my website, it'll bring up all the perimenopause and menopause-related podcasts that I've done. I can tell you from personal experience that a lot of women go from having super regular cycles to then having none, I've had women, as they get closer and closer to menopause, I've had a lot of other women that just start having more and more regular cycles, heavier, lighter, shorter, more frequent. For each one of us, it's really very unique. Sometimes, we can talk to our mothers to see what their experiences were like. But average age of menopause in the United States is 51. So, it's very likely you're very close to that period. Good luck. Do you have anything you want to add, Melanie?

Melanie Avalon: Well, first of all, I just knew that you'd be a wealth of knowledge about all of that. I'll just add two really quick things. I did find one really interesting review, especially because Deanna says, she likes reading and researching. It's called menstrual cycle variability and the perimenopause. It just talks about this whole transition, and process, and why those fluctuations might be happening. I always think it's funny when there's, what's the word, colloquial language, very casual language. The abstract is very scientific. It says, “another hypothesis is that the increased variability and that variability being the changes in your cycle” reflects “slippage of the hypothalamus, which loses the ability to regulate menstrual cycles at older reproductive ages.” Basically, the hypothalamus because it talks about how the dwindling pool of follicles is changing and creating changes. But I just love this concept of the hypothalamus. I don't know if I love the concept, but it's a funny concept to me that the hypothalamus is just--

Cynthia Thurlow: It’s a slipped gear. 

Melanie Avalon: Yeah. It's not quite handling the signals that are coming in and not quite sure what's going on, which would make sense with something like hormonal birth control or an IUD affecting those hormones and further exacerbating how the hypothalamus is interpreting what's going on. So, that would make sense.

Cynthia Thurlow: Do you want to know something interesting? In my book, I actually talk about the five phases of perimenopause, because there's just not enough research done in this area, but I'm getting ready to interview Dr. [unintelligible [00:46:49] Brighton, and there is some research to show that if you're on oral contraceptives for years and years and years, like many of us were including myself that it may actually hasten going into menopause. So, it's something that I'm going to talk to her about in greater detail, but the use of synthetic hormones may actually shorten that duration of reproductive years. I thought that was really interesting. For listeners, once I interview her, I will then feel more comfortable talking about that. But I do talk about in my book about perimenopause pretty extensively that there are these five identified phases of perimenopause. Do all of us go through each one of those neatly and nicely? Probably, not. But I love that you brought up the interrelationship between the HPA axis or HPO, hypothalamus pituitary ovarian axis. There were always constant communication and it's a slipped gear that it was working efficiently and now, it's like slipping a gear on a bike.

Melanie Avalon: That actually reminds me of, I would be curious if you have any thoughts on this. I interviewed Simon Hill this week. Do you know him? 

Cynthia Thurlow: I don't.

Melanie Avalon: The Proof Is in the Plants guy. He's really big in the vegan sphere. He was so nice. It was a really good episode. One of the things we're talking about, I don't remember why this came up, but we were talking about the role of reproduction evolutionarily, and how basically our bodies, the goal in our body from an evolutionary perspective is to have a child. And so, what I was wondering, I don't know if they've done studies on this and I haven't looked into this, but I wonder if you've had a child and you control for-- Let's assume that you have a child and you return, afterwards you regain your metabolic health to the same extent that you had it before. So, a healthy person who's equal levels of “health on both sides of a pregnancy” is her lifespan going to be shorter, because she's accomplished the goal compared to a woman who never has a child. If you haven't had a child as the body's still like, “We can do this.”

Cynthia Thurlow: These deep questions that Melanie comes up with I'm like, “I don't even know which angle to hit that from.” It's interesting because you'll see certain types of cancers are more prevalent in nulliparous, which means women who have not had a child.

Melanie Avalon: Oh, what's that word? I need this word in my vocabulary.

Cynthia Thurlow: Nulliparous. Yes, it's one of those weird, awkward medical words.

Melanie Avalon: Nulliparous. It a noun like I am nulliparous or it's an adjective?

Cynthia Thurlow: No, no, I am nulliparous or we would talk about a patient, this is a nulliparous female. 

Melanie Avalon: Oh, so adjective.

Cynthia Thurlow: Yeah. From my perspective, looking at it from the perspective of whether it's by choice or someone tried and couldn't does that put them at greater risk for certain types of disorders, cancers, etc. I come at it from a different angle. This is the thing I love about Melanie as my friend is that she comes up with such creative, interesting, refreshing takes on topics maybe that I've never even thought of-

Melanie Avalon: Thank you.

Cynthia Thurlow: -things I love about you, I'm like, “Oh, I hadn't thought about that before.”

Melanie Avalon: I love that you love engaging with the content or [laughs] just like, “Okay.”

Cynthia Thurlow: No, that's more to critically thinking. It's putting those thoughts out there.

Melanie Avalon: When I asked Simon about it, it wasn't the first time I thought about it. I think I thought about it a lot because I don't know, but I don't think I'm going to have children. And so, I'm so obsessed with longevity. I've thought about this concept a lot. Is this hurting or helping my longevity?

Cynthia Thurlow: I think I would probably guess it might help your longevity and I love my children. Let me be very clear. I was meant to be a mom, I'm happy being a mom, but there are moments in my children's lives that I know have hastened my longevity when I say this with love and reverence, I have a child who fell out of a second story window when he was two and had no injuries. Said same child when he was 10 years old-- 10, yeah, it was four years ago. 10 years old, coming back from all stars practice for swimming, fell off his bike and broke his arms, and needed emergency surgery, and walked in the house and his arms were concave, and I was like, “If any child has hastened my life, it's this kid.” I have no doubt there have been moments as a parent that have been terrifying and have likely killed off a lot of telomere length, and given me gray hair that I now pay copious amounts to cover up and that's a whole separate topic. But yeah, I would imagine it would probably help your longevity, Melanie. That's my guess.

Melanie Avalon: Oh, my goodness. Two quick things. One, he fell out of a two-story window?

Cynthia Thurlow: Yes. To give context to this conversation, this was the same week after his brother had fallen and broken his arm, and we had to take ambulance to a tertiary care center, because the hospital near my house would not reduce his fracture. My anxiety levels as a clinician were through the roof. Yes, and this child who we call him like MacGyver, he managed to open up a window out of curiosity, he was looking at something outside, pushed the screen and fell out two stories.

Melanie Avalon: Did you see him fall out?

Cynthia Thurlow: I did. I was sitting in the den and I saw a flash of red, and it was my two-year old, and it was the worst thing that's ever happened to us. 

Melanie Avalon: I can't even imagine.

Cynthia Thurlow: Yeah. And so, for listeners, he was fine. There was an ER physician walking her dog who was at his side and called EMS. I can get very emotional thinking about it. He was okay. We spent two days in the PICU and everyone was amazed, this kid did okay. From that point forward, I was like, “This kid is going to do big things,” because this could have ended very differently. I was an ER nurse, a trauma nurse. So, I've seen lots of horrible things happen with kids falling out of windows and the house that we lived in at the time any other window if he had fallen out if he would have fallen on something hard. 

Melanie Avalon: What did he fall on to?

Cynthia Thurlow: Grass. We had a bay window and so, he must have pitched himself in such a way that he bounced off of this other window, and then fell into the grass, and it had rained the night before. So, the ground was soft.

Melanie Avalon: Was he all scraped up?

Cynthia Thurlow: He had a scratch on his toe. When I say my kid is meant to do big things, [laughs] I have no doubt. But for the longest time, anytime, I heard an ambulance or a fire truck because the ER doc, who was at my son's side said, “If it were really bad, I would have called the chopper” and she's like, “You know that.” I was just like, “Whoa,” as a parent. Then the kid, when he was 10, fell and broke both his arms and had to go in for major-- He has plates and rods in his arms because he did such a bang-up job. I've told him, I was like, “Liam, I can't handle another big thing [laughs]. you have done it all.” Yeah. So, I think that being a parent is a wild ride and one that I'm grateful for. [laughs] I can speak from two experiences being a parent that have definitely aged my husband and we joke about it. We're like, “Yeah, he keeps us on our toes.” Actually, that's why we don't have any more children. We're like, “That was God's way of telling us we were done.” We have our hands full and he reminds us of that every day why he would never have been a middle child.

Melanie Avalon: Wow. Well, the second thing that reminded me up was, last night, I listened to Rhonda Patrick's newest episode. It's with a guy named Stuart Phillips. 

Cynthia Thurlow: Yes, I need to listen to that. 

Melanie Avalon: I really recommend it for listeners. It's a deep dive into protein intake and muscle. Really, really fascinating. A lot of stuff we talk about on this show. They talk about, do you really need the amount of protein that they say, and he argues that, yes, that dietary recommendations should not be called recommendations, they should be called minimal intakes. But he was talking about why when you're very young, you break a bone or something happens and kids, they don't need rehab or anything. The body fixes itself. And then when you're older, not so much. So, he just talks about that concept. So, I can put a link to it in the show notes. 

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Melanie Avalon: All right, shall we do one more question?

Cynthia Thurlow: Absolutely. This comes from Monica. Subject is: “Magnesium question.” “Can you share your favorite magnesium brand for sleep? I was using magnesium complex by Nature's Way. I ran out and I couldn't find it, and used another brand, and don't really care for it. Before I go looking for the Nature's Way, I wanted to see what you recommended. Thank you.”

Melanie Avalon: All right, Monica, thank you for your question. [chuckles] I always want to laugh when I get questions like this that are so perfect for what's happening in my life product wise. I feel like Cynthia I have to fill you in on all the inside jokes on this show. Gin and I used to laugh because one time we got an email from somebody who basically accused us of creating questions, making up questions to plug products or whatever and we were like, “If people knew how many questions we get, they would realize we would never need to [laughs] create a question.” We have hundreds of questions. But in any case, I did want to time this for this episode because I am currently this week. When this comes out, it will have already happened. But right now, the moment I'm in right now, we are launching my magnesium supplement this week, which is so so exciting. It's been such a long journey. That's with MD Logic. My first one, the AvalonX serrapeptase. This is AvalonX Magnesium 8 and then (broad spectrum complex). I know Monica's asking about sleep and I'm going to speak to that specifically because there is a certain type of magnesium that is better for sleep. 

But just in general, magnesium and my head has been literally yesterday was just magnesium all day. Researching, and writing, and getting together promo material, but basically, if you go into the literature on magnesium, it is shocking the extent to which this mineral is crucial for so many processes in our body. They used to say over 300 in somatic processes, but I found a really recent article, I think 2022 saying, actually, now it's over 600. It's involved in basically, every single cell, so a third of the magnesium is in our cells, two thirds-is in our bones, less than 1% is actually in our bloodstream, and the significance, on top of that it's actually highly controlled in our bloodstream. It's calcium. It’s how people will say that a certain diet might not affect your calcium levels and you can get a blood test and look at your calcium. But pretty much your blood calcium is probably always going to be in normal range. Things have to be really off for it not to be. 

The same is with magnesium, because so little of it is actually in the bloodstream. It might not be reflective of underlying deficiencies. It's so important. It's involved in energy production, creating ATP in the mitochondria, it helps create glutathione, so it can serve as an antioxidant, and then cardiovascular health, bone health, blood sugar control, muscle recovery, so many things, and of course, sleep, and mood. The AvalonX-- which was so exciting, you can buy this now. It is available. AvalonX Magnesium 8 will be great for all of that, it will also support sleep. So, Monica, definitely, definitely try that. On top of that there's a certain type of magnesium called Magnesium Threonate. It is actually a type of magnesium that specifically crosses the blood-brain barrier. It has an even more potent effect on sleep and relaxation. That would be something to consider. I'm going to be releasing a magnesium threonate probably next. So, stay tuned for that. I think we're going to call it Magnesium Nightcap or something. The reason Threonate is not in my blend is because you actually need a pretty high dose to get that therapeutic effect and so, we wanted it to be a separate add on type thing. But yeah, so basically, Monica, my recommendation is getting my Magnesium Spectrum 8, and then the Nightcap when it's available, and you can use the coupon code, MELANIEAVALON, and that will get you 10% off. So, that was a lot about magnesium. Cynthia, do you take magnesium?

Cynthia Thurlow: I do, I do. With my background in cardiology, I'm very mag savvy and I'm super excited about your new product. But if Monica is looking for something right now specific to mag L Threonate, while you're waiting for your next product to come out. I like designs for health. You're right. You do need quite a bit in order for it to be properly therapeutic, but that's actually the product I take before bed. I do take other types of magnesium during the day and I also fervently believe that people need both oral and transdermal magnesium to be able to absorb it properly. The product that I recommended to my cardiology, my electrophysiology patients, so people that were dealing with palpitations, and had defibrillator errors, and pacemakers, and all sorts of electrical issues with their heart, when I could get their magnesium levels more therapeutic, and then this started to work into all of my work with everyone. Everyone needs magnesium. There's no one listening who does not need repletion, we lose it when we're stressed, we lose it if we're having diarrhea, if we're having an acute illness. Certainly, when you travel, you're losing electrolytes. And so, I'm a big fan of transdermal applications. There's a company called Ancient Minerals. I have no affiliation with them. I just think they have high quality.

Melanie Avalon: I've used them before. 

Cynthia Thurlow: Yeah, they have sprays, they have lotions. I’ll typically recommend people spray. The oil is my first choice. Couple pumps into two hands, rub it on your trunk, your arms and legs, leave it on for 20 minutes. Use it before you get in the shower. You need about 20 minutes for absorption. When people do both of those things, they supplement with oral magnesium and they also use transdermal magnesium, they find that that is the perfect combination. For a lot of people, they need the additional, literally layer of magnesium to help them with sleep quality. Now, I'll be completely honest and say that when we get questions about sleep, there's so much that goes into sleep. Maybe we'll have to do a whole separate-- We’ll have to do a whole episode just talking about sleep modalities, because there are so many things that can impact our sleep quality. I know Mel and I are very, very proactive about our sleep and I feel I have maybe finally for myself found the right combinations and the right things that I do prior to bedtime and right before I go to bed that have really netted an impressive amount of improved sleep quality measured by Oura Ring data, etc. But I do think that using that two-pronged approach with magnesium is generally what I recommend. Transdermal and oral therapies, it sounds like Melanie has an amazing option right now. Magnesium L Threonate is the thing I think is so helpful for sleep and then using transdermal magnesium as well.

Melanie Avalon: Is it true? They say that this is why you experienced this and I experienced this that, if you put on a transdermal and it stings, they say it's because your skin is sucking it in so fast. That's why it stings. Do you know if that's true?

Cynthia Thurlow: Well, what I used to tell patients was that it was just validating that they needed more magnesium. Now, there are definitely people who are sensitive to magnesium. They'll feel tingly and it's uncomfortable. A little bit of tingle is expected. Really tingly, uncomfortable. 

Melanie Avalon: Mine was painful. 

Cynthia Thurlow: Yeah. Those people sometimes need the sensitive skin varieties of which Ancient Minerals has plenty of options. But I usually tell people, “It's just validation that you need to do this more often.” If you can tolerate, obviously, don't shave your skin and put it on. That would be torturing yourself. 20 minutes in your bathroom with your privacy, then jump in the shower. Some people don't like how it feels a little oily and I would say, just do it before-- I used to do before I would take a bath. I would literally just load up, do whatever I needed to do for bedtime, then get in the tub, then I would soak in more magnesium. I'm a little magnesium crazy. I'll admit after all the impressive things I saw it improve in patients, I was like, “This is something I need to commit to doing regularly.” But yeah, the tingle is generally a sign that needed the repletion.

Melanie Avalon: Gotcha. I'm glad you brought u, because I didn't even touch on how our modern lifestyles deplete our magnesium and-- [crosstalk] 

Cynthia Thurlow: Magnesium depleted soil. Just think about it. You could be eating all organic and you're just not getting the same nutrient profile that our grandparents did. It's just impossible.

Melanie Avalon: If you're eating conventional, specifically glyphosate, chelates, minerals. I know it can be controversial to talk about glyphosate. I literally read this in the PubMed scientific article I was reading.

Cynthia Thurlow: Have you interviewed Jeffrey Smith, yet?

Melanie Avalon: No. Ever since. [laughs] I feel so bad. I actually had it on my list to follow up with him. For listeners, he's a wealth of knowledge about GMOs, and glyphosate, and such.

Cynthia Thurlow: We'll plug my podcasts with him. But I interviewed him and the first thing I said to Melanie after I finished was, you need to interview him. He was just-- everything you wanted to know about GMOs, glyphosate in a way that is designed to educate and empower, and not scare the bejeebers out of you.

Melanie Avalon: What happened with that was he reached out to me independent of all of this and wanted to come on the show, and I got really excited, because I saw he had books on GMOs, and I was like, “Yes, I would love to do an episode on GMOs.” Then his people said, “Well, we really want to focus on his current work,” which was a little bit political and based on current events. I was like, “I just don't know if it's the best fit right now,” because this was a while ago and this was in the heat of a lot of political stuff. I don't think I really realized who he was. If so, I think I would have handled that differently and I reached back out to him ever since you told me about it, but I haven't heard back. So, I need to reach out again, because I really want to interview him now.

Cynthia Thurlow: I think you'd really like him. I know your listeners would really enjoy that conversation, too.

Melanie Avalon: Yes, to-do list. And then I will say just one last thing before we go. All the supplements that I make, I really wanted to make the best form of the supplements on the market and only what I would want to put in my body. It's free of all potentially problematic fillers, it's tested for allergens, super, high-quality, it has activated cofactors to help absorption, so, it has methylated B6, and then it has chelated manganese, because magnesium can actually reduce your manganese levels, so, it's to help with that. Definitely the way to go and that is again, avalonx.us, not to sound like a commercial. But this was absolutely amazing. I've missed talking to you, Cynthia, because it's been so long.

Cynthia Thurlow: I know. But the cool thing is, we're recording a second episode right after this.

Melanie Avalon: I know. [laughs] So, here we go. Well, this has been absolutely wonderful. A few things for listeners before we go. If you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. You can get all the stuff that we like at ifpodcast.com/stuffwelike. You can follow us on Instagram. I am @melanieavalon, Cynthia is @cynthia_thurlow_ and we are @ifpodcast on Instagram, and I think I'll open up next week with something that we're talking about sleep. I started using something that I think has had a massive influence on my Oura Ring. So, maybe I'll start with that. All right, well, for listeners, this has been absolutely wonderful and I'll talk to you next week. But I'll actually talk to you right now. [laughs]

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and recomposed by Steve Saunders. See you next week.

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Jun 12

Episode 269: Heavy Meals, H. Pylori, Digestive Enzymes, HCL, Modified Keto, OMAD, Lowering Fat, Measuring The Fast, And More!

Intermittent Fasting

Welcome to Episode 269 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

BUTCHERBOX: Grass-Fed Beef, Organic Chicken, Heritage Pork, Wild-Caught Seafood: Nutrient-Rich, Raised Sustainably The Way Nature Intended, And Shipped Straight To Your Door! For A Limited Time Go To butcherbox.com/ifpodcast And Get Free BACON For LIFE Plus $10!!

 JOOVV: Like intermittent fasting, red light therapy can benefit the body on so many levels! It literally works on the mitochondrial level to help your cells generate more energy! Red light can help you burn fat (including targeted fat burning and stubborn fat!), contour your body, reduce fine lines and wrinkles, produce collagen for epic skin, support muscle recovery, reduce joint pain and inflammation, combat fatigue, help you sleep better, improve mood, and so much more!! These devices are literally LIFE CHANGING!! For A Limited Time Go To Joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

BEAUTY AND THE BROTH: Support Your Health With Delicious USDA Organic Beauty & The Broth Bone Broth! It's Shelf Stable With No Preservatives, And No Salt Added. Choose Grass Fed, Grass Finished Beef, Or Free Range, Antibiotic And Hormone-Free Chicken, or Their NEW Organic Vegan Mushroom Broth Concentrate! The Concentrated Packets Are 8x Stronger Than Any Cup Of Broth: Simply Reconstitute With 8 Ounces Of Hot Water. They’re Convenient To Take Anywhere On The Go, Especially Travel! Go To melanieavalon.com/broth To Get 15% Off Any Order With The Code MelanieAvalon!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get Free BACON For LIFE Plus $10!!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist, And Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

BEAUTY AND THE BROTH: Go To melanieavalon.com/broth To Get 15% Off Any Order With The Code MelanieAvalon!

Listener Q&A: alexa - IF foods

Listener Q&A: Leah - Coffee Differences

Square Feet Specialty Coffee

JOOVV: For A Limited Time Go To Joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

Listener Q&A: Trina - Keto AND OMAD question

Summary of Women, Food, And Hormones: A 4-Week Plan to Achieve Hormonal Balance, Lose Weight, and Feel Like Yourself Again (Sara Gottfried, M.D.)

MenuPause: Five Unique Eating Plans to Break Through Your Weight Loss Plateau and Improve Mood, Sleep, and Hot Flashes (Anna Cabeca, DO)

#157 – AMA #22: Losing fat and gaining fat: the lessons of fat flux

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 269 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment. And no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine if it's that time and get ready for The Intermittent Fasting Podcast.

Hi, friends. I'm about to tell you how you can get sugar free, nitrate free, heritage breed bacon for life, plus $10 off. Yes, free bacon for life, plus $10 off. We are so honored to be sponsored by ButcherBox. They make it so, so easy to get high-quality humanely raised meat that you can trust. They deliver 100% grass-fed, grass-finished beef, free range organic chicken, heritage breed pork, that's really hard to find by the way, and wild caught sustainable and responsible seafood shipped directly to your door. When you become a member, you're joining a community focused on doing what's better for everyone. That includes caring about the lives of animals, the livelihoods of farmers, treating our planet with respect and enjoying deliciously better meals together. There is a lot of confusion out there when it comes to transparency regarding grazing practices, what is actually in our food, how animals are being treated. I did so much research on ButcherBox. You can actually check out my blog post all about it at melanieavalon.com/butcherbox. But I am so grateful for all of the information that I learned about their company. All of their beef is 100% grass fed and grass finished that's really hard to find. They work personally with all the farmers to truly support the regenerative agriculture system. I also did an interview with Robb Wolf on my show, The Melanie Avalon Biohacking Podcast, all about the massive importance of supporting regenerative agriculture for the sustainability of not only ourselves, but the planet. This is so important to me. I'll put a link to that in the show notes. 

If you recently saw a documentary on Netflix called Seaspiracy, you might be a little bit nervous about eating seafood. Now, I understand why ButcherBox makes it so, so clear and important about how they work with the seafood industry. Everything is checked for transparency, for quality, and for sustainable raising practices. You want their seafood, the value is incredible, the average cost is actually less than $6 per meal, and it's so easy. Everything ships directly to your door. I am a huge steak lover. Every time I go to a restaurant, I usually order the steak. Oh, my goodness, the ButcherBox steaks are amazing. I remember the first time I had one and I just thought, “This is honestly one of the best steaks I've ever had in my entire life.” On top of that, did you know that the fatty acid profile of grass-fed, grass-finished steaks is much healthier for you than conventional steaks. And their bacon, for example is from pastured pork, and sugar and nitrate free. How hard is that to find? I'm super excited, because ButcherBox’ bacon for life is back and it's even better, because you get $10 off as well. Yep, right now, new members will get one pack of free bacon in every box for the life of your membership, plus $10 off when you sign up at butcherbox.com/ifpodcast. That's one pack of free bacon in every box for the rest of your life, plus $10 off. Just go to butcherbox.com/ifpodcast. And we'll put all this information in the show notes. 

And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense, because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly, one of the most influential factors in weight gain? It's not your food and it's not fasting, it's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup maybe playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That's because ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years 

Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so, you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life and their makeup is amazing. Check on my Instagram to see what it looks like. Tina Fey, even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products. Deodorant, shampoo and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my clean beauty email list, that's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. And you can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well. 

And lastly, if you're thinking of making Clean Beauty and Safe Skincare, a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show.

Melanie Avalon: Hi, everybody and welcome. This is Episode number 269 of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow. How are you today, Cynthia?

Cynthia Thurlow: I'm doing well other than two surly teenage boys.

Melanie Avalon: When did they get out for school?

Cynthia Thurlow: Officially on June 2nd. We've already had the award ceremonies, and I'm happy to report they had high academic honors, which was awesome. But they are teen boys and they did not permit any photos to be taken of them. And so, all the friends of mine that have daughters, there were pictures of the family, and their awards, and my kids, no, not so much. I took pictures from far away and I just decided I was like, “There are battles worth fighting and this is not one I choose to fight.” But yeah, they will officially be out on June 2nd and I'm pretty excited. This is really their first full year of school in two years, to be physically in school, the entire school year. 

Melanie Avalon: Oh, wow. That's crazy. 

Cynthia Thurlow: No, the pandemic has definitely-- It's not just my kids, it's every child, every family has been impacted by the pandemic. For me, I'm just so grateful that they were in school for an entire year. Things that you take for granted that we never imagined we would have two years of or a solid year of being at home and being in school, and then partial back to school last year. So, I'm just grateful they got to be in school with their peers, part of the year unmasked, then they've been doing really well, despite all the stress and the drama of the last two years. 

Melanie Avalon: I'm getting flashbacks now. There's something so glorious and wonderful when you are growing up and summer vacation. It is just so exciting. [chuckles] 

Cynthia Thurlow: Well, it's done and to be honest with you as a parent, I always really, really looked forward to mid-May, because all of a sudden, the sports were over, [unintelligible [00:09:40] education was over, it was like the carpool nonsense that all parents go through just stops. And so, they would just go to school, and they would come home, and it was just a lot more togetherness, and they're probably getting more sleep, and my husband and I are obviously spending less time driving back and forth between multiple sports. It gives you a prelude to what the summer is going to be like. For me, I'm very much the kind of mom where I let my kids sleep in. They have chores, but I like them to actually decompress. I'm not super strict as long as they get their work done. I know that may be a departure from some families that are listening, but I've just come to understand like, “My kids do really well in school and they're good kids.” I let them do a lot of decompression activities during the summer. 

When they were younger and they had to be in a structured activity, because they had so much energy, and they needed an outlet. Now, it's more thinking about what college does my oldest one to apply to. He's leading into STEM curriculum. Looking at AP classes and it's so different. You really develop a very different relationship with your kids as they're getting older and so, it's also to me picking my battles, So, it's less about keeping them under my thumb, and forcing them to do so many hours of reading every day, and now, it's a different playing field.

Melanie Avalon: That's very much the way I was raised as well. My parents were like that. Of course, I was very on top of things. I remember for summer reading, I would read the books a minimum of two times, sometimes more, which looking back, I'm like, “Why did I do that? Why did I read The Hobbit twice after already having read it” in the past as well?

Cynthia Thurlow: That doesn't surprise me that you would be a willing overachiever. Not someone who's doing it for any other reason than to thoroughly be invested, and really understand, and comprehend what you're reading. I love that we both share that although, we would not have been in school at the same time together. I do love that we are both very cerebral and enjoy-- Just enjoyed learning. What a blessing that is, right?

Melanie Avalon: Speaking of, Gin and I used to always talk about, “Would we be friends in high school and will we be at the same lunch table?” We decided that we might be, but probably not, probably slightly different lunch tables. Which lunch table were you at in high school?

Cynthia Thurlow: It's ironic that in high school and in college, I was part of a very popular crew. However, in my popular career, there was the subcategories of popular girls and I was part of the smart girls that got good grades, and weren't promiscuous, and had boyfriends, but we were nice to people. To me, at that stage, it was actually cool to be smart, whereas the people who were the creme de la creme popular people didn't care about school. I just stayed focused on like, “I want to go to college, and I want to do this, and I want to do that, and I know I'm not going to stay in this school.” But I was always nice to everyone. I was also vice president of my class and captain of back in the day I played field hockey. To me, it was important to just be kind and nice to people. Yeah, my kids cannot believe that I was popular. They're like, “You're so dorky and nerdy,” and I'm like, “Oh, but it's all in the down low. No one knows that unless they know me well." How about you? I would imagine you were like top in your class and super, super, super smart.

Melanie Avalon: There's the honors English class and it was basically the really intellectual “smart kids.” But it was similar. It had some popular people from the popular crowd in it. It was just like the nice, smart people. That was my main group. Yeah, I really excelled academically. You probably would have been at my school in the honors English group class. But you would have been in the popular like the popular people who are in the honors class.

Cynthia Thurlow: Yeah. It's funny because I had this not so nice high school boyfriend. When I look back and he used to call it the nerd herd. He would make fun of the fact that I was in AP classes and honors classes, and I was like, “Who ended up doing better?” Looking at where he is and where I am, and let me be clear, I'm friends with his wife, and his mom, and his sister. I have a very nice relationship with all them. But I look back that he would like tease me and I was like, “There's nothing to be ashamed of for being smart. Smart people run the world.” That's my feeling. It's good to be smart.

Melanie Avalon: I love it. By the way you interviewed Robb Wolf again, right?

Cynthia Thurlow: I did. He's so wonder-- It’s such an easy interview because he's just so gracious and humble. With my cardiology background, we’ve talked a lot about electrolytes and we did talk about overtraining, because I know and I'm very aligned with his perspectives on the overtraining goes along with the over restriction of food, goes along with over fasting, goes along with plateaus. We did touch on that which was really important to me, because I wanted him to also know, there are clearly people that go overboard with all of the above, but it was a really nice conversation. It was nice for someone else to talk about the value of electrolytes and not just me saying, “Oh, by the way, I worked for 16 years in cardiology and I got really, really good at replacing electrolytes.” I got really good at replacing electrolytes and no one really wants to hear about that because it seemingly seems so insignificant, but yet, it's so important. I was actually saying, “Robb, I had surgery almost a month ago” and I knew that my body was going to take a hit, because of this orthopedic surgery, and I was telling him, I said “My HRV, my heart rate variability has really been in the toilet.” [laughs] Clearly, as well as I'm sleeping, my body still perceives, there's all this ongoing stress and my cortisol levels must still be dysregulated. I said, “I just kept adding more sodium and they kept coming down.” I said, “It's just so amazing, something so simple.” It can be so helpful. So, yes, Robb was amazing. Then the other guests that I had most recently that really just-- I'm still in such awe of my conversation with Sara Gottfried, which I know you interviewed her recently as well and she's just so-- [crosstalk] 

Melanie Avalon: We pushed it. So, it's in a few weeks. 

Cynthia Thurlow: Oh, sorry. Well, mine just dropped. When I was listening to it, I feel so very grateful as I know you do that we have platforms in which we can connect with such profoundly influential individuals in the space and be able to share all of their wisdom with the world.

Melanie Avalon: Yeah, I am so, so excited to interview her. It's really exciting. 

Cynthia Thurlow: She's so smart. 

Melanie Avalon: Yeah, this upcoming week for me is actually unique. I'm only going on a podcast. I don't actually have an interview, but I'm scrambling. Every now and then, I have a little panic moment where like, “How am I going to prep everything?” But [chuckles] then I take a moment and I breathe. I'm really excited about the lineup. Oh, that's the next person I'm interviewing, Mark Sisson.

Cynthia Thurlow: No way. 

Melanie Avalon: I'm so excited. [chuckles] 

Cynthia Thurlow: Did you sacrifice your firstborn child? 

Melanie Avalon: Basically. [chuckles] 

Cynthia Thurlow: I say that very lovingly. The facetious future born child, I'm like, “That's awesome.”

Melanie Avalon: That's going to be a really, really surreal moment, because it's surreal anyways with all the people that I get to interview, but really there's a handful of people that are the people I've been following from day one. It's basically Robb, Mark Sisson, Dave Asprey, probably those three. Yeah, and I haven't interviewed Mark. 

Cynthia Thurlow: That's so cool. Did I tell you that a couple years ago, I literally ran into him because I wasn't looking where I was walking.

Melanie Avalon: No way. 

Cynthia Thurlow: And he could not have been more polite. I remember, I was so like, “Oh, my God, I just ran into Mark Sisson” and he was so polite.

Melanie Avalon: I got connected to him through Brad Kearns, who I'm pretty good friends with who's coauthor. And so, I've been talking with Brad about what direction to take the interview, because there're so many ways you could go, but I think I might focus more on him. His personal life, because he's done so many businesses, and I would just love to hear all about that rather than focusing on the primal stuff as much.

Cynthia Thurlow: I think that's so exciting. I'm so excited for you. It's interesting because a lot of these people when you've been following them for a long period of time, that's how I felt about Sara Gottfried in addition to the other people you mentioned. When I was talking to her, I was trying not to fan girl. I was really nervous. I told my husband, I was sweating, I tried to be as cool as I could be, [laughs] but to actually meet some of these people that we've been following for years, and valuing the message and methodology of their brands and their vision and to me its-- I tell everyone all the time like one of my greatest blessings in my business is being able to podcast because as you've said it's the best way to network. You just don't even realize how important it is until you get in a position where you either meet someone in real life and you're like, “Oh, my gosh.” I mean, you really do become friends and acquaintances with so many of these people. We're all trying to positively impact lives in a way that leaves people better off and to me, it's so amazing. So, I love that you-- That was probably a year or two ago, you're like, “Podcasting is the best way to network” and I was like, “Oh, my God, that's exactly what it is.”

Melanie Avalon: Because it's basically conversations that aren't superficial, because they're deep conversations where you're talking about their work, and you're really connecting, and then you're just doing that regularly, and it's all the amazing people. So, I'm just so grateful. I'm really in awe.

Cynthia Thurlow: Well, and for anyone who doesn't know this about you, I do know this about you. I probably spend five to 10 hours per each podcast, just organizing, listening to other podcasts, trying to get a sense for what the person's like. Melanie is next level, because she is graciously on a few times shared her notes and they are so detailed. For anyone that's listening, you have no idea. When Melanie says she's preparing, she's preparing to go do a doctoral dissertation. She's so well prepared. If you don't know that about her, you should know that about her. So, as I say, you always encourage me to level up how I prepare and how I get ready for my own podcasts.

Melanie Avalon: Well, thank you so much. I echo that back to you as well, because I feel there are a lot of podcasts out there. and there are a lot of people who don't prepare, and do just show up, and I get the exact same sense from you with the preparation. So, yeah, it's a good place to be. 

Cynthia Thurlow: Absolutely. I can tell you now that I've been on the other side having had a book launch, the people that were prepared, I really appreciated that because you get to a point where you're just doing so much press that you're exhausted. I remember, there were weeks where I was doing 12 to 15 podcasts a week on top of other media and you were like, “Where do I need to show up and what am I talking about?” You were just showing up, and being yourself, and being enthusiastic, and I would have people, they're like, “Yeah, I haven't really read your book and just tell me what you want to talk about?” I was like, “What?” [laughs] I was like, “Not even a skim, not even read the appendix or read the table of contents anything.” When there's no judgement, sometimes, I was like, “Oh, man, this is going to be harder than I thought.”

Melanie Avalon: When people ask me basically to provide all the questions for the interview. I still do it and I'm so grateful, but I appreciate it much more, like you said, when it's really evident that they've read the book, and they come with the questions, and everything.

Cynthia Thurlow: Well, and it's interesting, because I interviewed Dr. Avrum Bluming and Carol Tavris about their book, Estrogen Matters. It was funny. After we recorded, they both said to me, “Cynthia, your assistant reached out to us and asked us to tell you what we wanted to talk about.” They were taken aback and they said, “But now that we've met you, we understand that you really just wanted to make sure that you are aware of what we thought was most important.” But by the same token, you did so much prep work like that podcast, I probably spent more time on than anyone I've done this entire year, because I felt the Women's Health Initiative as an example, had led so many clinicians and patients to be fearful of hormone replacement therapy and I was like, “I know, I've got this platform.” So, I think in most instances, I really endeavor to think about how do I ensure that person knows I value their time, but also let them know like, “I'm in the game, and I'm super prepped, and I've read all your stuff, and I've outlined, and I've listened to podcasts to just to get a sense.”

I just interviewed the head researcher for HVMN and he was so delightful. He was like a Rick Johnson-esque person. So enthusiastic, so excited. He was able to translate the science into layman's terminology and that was such a joy, and I was like, “Wow.” I was so surprised. I instantly liked him and I thought to myself, “This is what's so awesome to be in this space.” We can actually have these opportunities to take real research and make it relatable for the average person, because that's really the platform that I think we're both on, although obviously you're on a biohacking platform and I'm on a 35 and up trying to translate how to navigate our lives without too much stress and distress.

Melanie Avalon: Two thoughts to that. One, so, the way I tackle getting the vibe of what they want to talk about while also having them know that I value their time, I just in the intake form, all of the questions are optional and there's just one question that says, “Are there any topics in particular you'd like to talk about?” Rather than asking like, “What questions you want me to answer?” It's just very open, I feel that accomplishes that goal, at least for me.

Cynthia Thurlow: I may have to borrow that. Of course, with credit given to you.

Melanie Avalon: No, I don’t need. No credit needed. I probably took it from somebody else. The second thought was, I was listening as per usual last night to a Peter Attia episode and they were talking about, it was one of the Q&As and the cohost was saying, how he always will reach out. When he read studies, if he has questions, he'll literally just email the researchers on the studies. The majority of the time they always answer and usually are really excited to talk about the studies. So, I was like, “I should start doing that.”

Cynthia Thurlow: Yeah. Well, you know what's interesting is, so, Dr. Bluming, who I just bow at his feet, his book is so amazing, and he sends me updates. He just did an editorial for a journal and sent me the update and I was like, “Thank you so much. I can't wait to read it.” I meant it genuinely, because he's helping to change the narrative, and the discussions around, and the fears around prescribing and taking hormones. I was like, “He's doing amazing, amazing things.” Yeah, they love to talk about that stuff.

Melanie Avalon: And for listeners, this is Cynthia's Everyday Wellness Podcast.

Cynthia Thurlow: That podcast dropped in February and as you know, I'm a big nerd. I like to look at my metrics. Number one for the year thus far is Megan Ramos and then, Rick Johnson. 

Melanie Avalon: I'm interviewing her in a few months. 

Cynthia Thurlow: Yeah, there's no comparison. Her downloads are way more than anyone else's. And also who else is in there? Dr. Bluming is in there. So, clearly, these are concepts and methodologies that are really relating to people, which I think is great. Yeah, but Rick Johnson's amazing,

Melanie Avalon: I should look at my stats and see which ones were the biggest.

Cynthia Thurlow: Yeah, I trend it. I don't know if it makes me, like, it just allows me to see who do I want to bring back, what really resonates, what was a do-do? I think sometimes, you do a great interview, and it just doesn't resonate with your listeners, and you're like, “Gosh, that was surprising.” And then sometimes something that you-- [crosstalk] 

Melanie Avalon: Or, the reverse. Yeah.

Cynthia Thurlow: Correct? [laughs] That happens, the unicorns are like, “Where did that come from?”

Melanie Avalon: For me, I have genuinely, because people will ask me, I think actually, you've asked me before like, “Has there ever been an episode that I didn't want to air or didn't really like?” I can genuinely say, I have really loved every single interview that I've done. But sometimes, I do an interview and I love it, but I just don't know if the topic or the content will really resonate. Yeah, sometimes, I'm really surprised that they freak out and [chuckles] love it.

Cynthia Thurlow: Yeah, I've only had three and almost four years of podcasting that I had to toss in the toilet, which is always disappointing. But I was like, “Sometimes, you just don't get a good interview.” You could have someone that's super smart and they're just not easy to interview or they go off on a tangent that is so not aligned with your own methodology that you're like, “I can't release this, because it would be a problem.” But yeah, I think that's how you just navigate knowing what your audience really wants to hear and resonate with.

Melanie Avalon: Definitely. Well, before we jump in, I have one really quick baby teaser and this is going to be such a vague teaser. But for listeners, I am so excited because in creating supplements now, there are a few supplements that I really want to create, but I don't know if I can, or it might be tricky, or things with like FDA regulations and such. So, this is just a baby teaser that I found out yesterday or the day before that one of the main supplements I want to make that I thought we couldn't, we probably are going to be able to, because we might have an FDA approved version. So, I get really excited. 

Cynthia Thurlow: Now, I can’t wait to hear more. 

Melanie Avalon: For listeners, if you'd like to know what that is, definitely get on my supplement email list because that's where I will be announcing the news. Also, I keep getting questions literally every day about when am I going to be releasing my magnesium supplement. The email list for all the information is avalonx.us/emaillist.

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Melanie Avalon: Shall we jump into everything for today?

Cynthia Thurlow: Let's jump in.

Melanie Avalon: To start things off, we have a question from Alexa and the subject is: “IF foods.” Alexa says, “Hello, ladies. I'm on my second week of IF clean and I'm loving it. I tried IF last year, but was not doing it correctly as I was still putting creamer in my coffee. I recently found your podcast and I'm hooked. My question is regarding the type of foods I'm consuming after I break my fast, which I've decided to begin with a 16:8. I find that sometimes, I get hungry early between 9:30 to 10 AM, then it goes away. I noticed once I get past noon, sometimes, I can push through to about 1:00 to 1:30 PM usually, because I'm busy working. But I seem to gravitate towards a heavy lunch. For example, a tuna melt, bag of chips and water, or sometimes, I'll have Mexican tacos that are super delicious. Typically, carne asada or other type of meat. I am just wondering if I should be careful about breaking my fast was such heavy food. Also, sometimes, I don't get too hungry for dinner, so I'll have a light dinner. Do you have suggestions on how to eat correctly when IFing. I forgot to mention that I also work out three to four times a week. Thank you and sorry for all the rambling.”

Cynthia Thurlow: Well, Alexa, I think first and foremost, just the fact that you're asking if you need to break your fast with a lighter meal demonstrates to me that you're already thinking that might be a problem. I typically recommend that you break your fast like maybe start with some bone broth as a light alternative or a light salad, and then perhaps, have a less complicated meal like maybe you're having some chicken, or some steak, or you're going to have a bison burger, or you're having a piece of fish with some vegetables like non-starchy vegetables, because it could very well be that between the mayonnaise, and the cheese, and I don't know if you're making the Mexican tacos or buying them out, you can be exposed to seed oils. It might just be overwhelming your digestive processes. So, that's my first thought is break your fast with something lighter and less fat dense that might be part of it. 

The other thing is, depending on where you are in your cycle, so, I don't know if you're still menstruating. I am an advocate of women. You can get away with intermittent fasting for usually the first three weeks of your cycle. But if you're within a week of getting your menstrual cycle or bleed week, then I typically recommend you back off. The fact that you are feeling like you're having such a heavy meal and then you're not really hungry for your second meal makes me concerned that you may not be hitting your protein macros. For anyone who is new to listening to me on the podcast, I'm all about protein, protein, protein. We really need it for so many reasons. One of them is satiety and other one is to have adequate muscle protein synthesis. Hitting those protein macros is going to be really important. So, I would probably recommend you start with a lighter meal when you break your fast, so that it'll allow you to get in enough protein between your two regular meals during your fasting window.

Melanie Avalon: That reminded me of the interview that I did have in the interim since we talked which was Dr. Gabrielle Lyon, who is as well all about the protein, and really, really knows the science of it, and why it's so important. I really can't wait to air that. I agree with everything that you said. I like what you said about the fact that she's asking means that she might be intuitively on to something. I do think that this is something pretty intuitive because we are really, really unique everybody, individually. Some people can handle having a big bolus of food and be fine, and some people are delicate butterflies, and need to really take a more measured approach like Cynthia said with maybe breaking with bone broth, or something more gentle. I found for me, I break my fast, I post about this all the time on Instagram so people know, with cucumbers and wine, but then I move into a really heavy meal, actually. But I do slowly ease into it. I will say, if you are eating heavier--

I don't know if we need to define what heavy mean, because on the one hand, you could have a meal like I eat, where it's a huge amount of protein, which would seem like a “heavy meal.” But it's not necessarily heavy in the sense that it's a lot of mixed macros, and fat, and processed foods and that type of heavy. I think heavy can mean different things. Mine's just heavy in a mechanical sense and that protein requires a lot of energy to break down. There's a reason it has the highest thermogenic effect of any food. You “burn” about 30% of the calories and protein just by breaking it down because it does require a lot of digestion and energy to do that. All that to say if you do want to eat “heavier meals” and find that you're not digesting it well, you might want to consider HCI supplementation and/or digestive enzymes. That might be something that can really help. I've always been really fascinated in the ordering of it, because the natural digestion process would happen in a certain order. So, basically, we release stomach acid first, HCl and then later as the food moves into the intestines that's where enzymes process that. I've always been a little bit haunted about just there needs to be a certain order to it. I've asked a lot of guests this and I get different answers. But the way I do things is I use HCI first in my meal and then I add digestive enzymes afterwards. So, that might be something to consider. I don't necessarily think there's a correct way, but we are really individual and it's good to be intuitive.

Cynthia Thurlow: Well, this is just my little clinician caveat that in the past two years, I have not done one GI-MAP, maybe one or two out of hundreds of women that hasn't had H. pylori. I tend to be a little more conservative with recommending betaine or HCl, because if someone has an active or unknown H. pylori infection, that can actually exacerbate symptoms. I would say that under normal circumstances, I think digestive supports are great. But I think of in the hierarchy, digestive enzymes are pretty benign, but I tend to be a little bit more conservative about HCI just in case someone has H. pylori, which, if you're not familiar what that is, it's opportunistic organism that sometimes in the setting of low hydrochloric acid can flourish. And so, I'm just seeing so much of it now on GI-MAPS, which is a DNA based stool test that I'm tending to be really conservative with HCl until I have testing. So, I agree with everything that you're saying. 

However, that how we define a heavy meal might be different to each one of us, but I define a heavy meal is something that's going to be harder on our body to digest. If you're not making the tuna melt, you don't know what the ingredients are, if you're not making those Mexican tacos, you don't know what seed oils are being used and so, that could be contributing to why it's feeling like you're having a little bit of a digestive backup or just feeling very full. The other thing is if you're sleepy after a meal that could be a sign that not only is it too large of a meal, but you might have eaten enough carbohydrate that you're getting some degree of blood sugar dysregulation. If that persists, you may want to check your blood sugar. I think that's certainly really reasonable. Glucometers are very inexpensive, but your blood sugar should come back to baseline within two hours of eating ideally, just a thought.

Melanie Avalon: Question about the H. pylori. So, it flourishes in low HCI environment or high HCI environment?

Cynthia Thurlow: No, low. Because it's like anything. We start producing less hydrochloric acid as we get older. It's much more common to see HCI flourishing, because it's the first line of defense. Hydrochloric acid is designed to kill things. If you have inadequate levels and certainly it gets depleted, you can get HCI depletion just from not having enough precursors like certain types of zinc. I remind people that until proven otherwise, until I know someone definitely doesn't have H. pylori, and this is just my own clinical environment. My sometimes will hold off on doing HCl, but there's certainly other things you can do to help support digestion. As you mentioned, digestive enzymes are great. I'm just seeing so much H. pylori now, I think it has a lot to do with the impact of stress on the gut microbiome. That's been my working hypothesis that the doctors at the GI-MAP lab agree with, because I've never seen so much H. pylori, never.

Melanie Avalon: Wouldn't taking HCI benefit that then?

Cynthia Thurlow: You have to kill the infection. You remove what doesn't belong and think about it this way. If you are getting H. pylori and you're taking a stool sample, it's gotten from the stomach through the entire digestive system, small intestine, large intestine, into the rectum and expelled. Whatever amount you're seeing quantified on DNA based technology is actually higher. We eradicate first and then we go to supplementation with HCl. But it's usually created in a low hydrochloric acid environment and that's oftentimes related to age-related changes or people don't have the cofactors to be able to create enough hydrochloric acid. That's where I go from, and that's what I was taught, and it's definitely been my clinical experience to see that that you want to make sure that you're not addressing HCI issues if someone has H. pylori.

Melanie Avalon: Okay, I'm still not following. If the problem with H. pylori is low HCl because of the ulcers.

Cynthia Thurlow: Well, there's many different types of H. pylori, and so some are prone to precancerous lesions, they can lead to certain types of duodenal ulcers, etc. When you do the testing, especially the type of testing I mentioned, it'll help you differentiate if they have any of the pathologic cofactors that go along with it. But here's the thing. If HCl is at a proper level, you should not have an issue with H. pylori. It's in the setting of a low hypochlorhydria. In that setting that is when you can make this opportunistic opportunity for things not to get killed off, that could be a parasite that you ingest. And yes, it is as horrifying as it is to think. We ingest a lot of things and we are dependent on this first line of defense in our stomach to have enough hydrochloric acid to kill things off. But what I see in most women that I work with is that they do not have optimal levels of hydrochloric acid and therefore, it bypasses this first line of defense. We should not have H. pylori in our stomach. Certainly, not at detectable levels. With DNA based stool testing, you are seeing signs of a mechanism that could be also a reflection of the impact of stress on the gut microbiome, because we know that impacts immune function as well.

Melanie Avalon: So, the reason not to take the HCl is, so that you can test and see if you have H. pylori. 

Cynthia Thurlow: Well, that's one of the reasons. But that’s also, sometimes, people will start H. pylori and they all of a sudden get reflux, or they're burping a lot, or they're nauseous, or they're bloated and so.

Melanie Avalon: They start HCl or they start--?

Cynthia Thurlow: It can exacerbate their symptoms from H. pylori. Sometimes, it can be very subtle. They might just have bloating and they just assume bloating is normal like, “Oh, I had dairy and I'm bloated” or “Oh, I had some gluten and that's why I'm bloated.” But it could in fact be related to imbalance in the gut microbiome. There's a lot to unpack here, but certainly H. pylori is an opportunistic infection and more often than not it is attributable to a low HCI environment in the stomach.

Melanie Avalon: Okay. [chuckles] I'm just not understanding if it's attributable to low HCl, what is the reason for not taking HCI?

Cynthia Thurlow: Because you have to kill the infection, you remove what does not belong before you start adding digestive support like that. This is a clinical thing like this is a best practice thing. This is something that I learned in school and has been the case I don't start hydrochloric acid, unless I'm sure someone has cleared H. pylori. You think about digestion from a north to south process, what's in the stomach, you have to address what's there before you address Candida, or a parasite, or dysbiosis, or any other worms, which occasionally come up on diagnostic testing. You start north to south and so, you have to eradicate what does not belong in the stomach before you start addressing things that are going on lower in the digestive system.

Melanie Avalon: Oh, okay. So, I just really want to understand what you're saying. To resay what you just said, you need to address these infections before you work on digestive support as a solution.

Cynthia Thurlow: Well, you want to. Before you prescribe or recommend HCl, you want to make sure they don't have H. pylori. That's where it stems from. If they don't have H. pylori, you could absolutely start hydrochloric acid. More often than not, people will see improvement in protein and amino acid breakdown. For many people that can be a simple fix to why they struggle with a protein bolus. But I always like to be thinking as a clinician and that's one of those things I always say, more often than not hydrochloric acid is pretty benign. However, here's my caveat in my clinical experience. “You want to be careful about dosing it if you haven't already ruled out H. pylori.” There's just so much of it. I have seen more in the past two years than I've seen the last 10 years. That's how much I've seen.

Melanie Avalon: Is that an easy test? Can people ask their practitioner for that test or would it be a GI doc that normally does that? I know you're not a GI.

Cynthia Thurlow: I would say it's someone that's functionally or integrative medicine trained. For me, before I started working with the DUTCH, I think the GI-MAP is one of the best tests I've worked with, because it's a starting point. It's been my experience that most primary care providers, internists, and most traditionally trained gastroenterologists are not using it. Because it's not part of that allopathic medical model. It doesn't mean that it's not valuable, but for a lot of people they do pay out of pocket. That can be something that's limiting. I've had people come to me who've been to their traditional, they've done the GI workup, they've had breath testing for H. pylori, and I tell everyone, the gold standard is stool. The best way to rule out H. pylori as disgusting as it is because think about it. H. pylori is in the stomach. If you get a positive test with stool that means it made it all the way.

Melanie Avalon: So, it won't find the dead DNA?

Cynthia Thurlow: Well, you're shutting it. It's really going in with testing. I can send you some of the information, so you can learn more about the testing. But it's been one of those things that that amount of shutting, if you get it all the way into your stool is pretty significant. I always say to people like, “Yeah, the numbers not all that high, however.” [laughs] We weren't going into your stomach and taking the sample there. Breath testing is not as reliable. If anyone's listening and they've had that testing, I oftentimes will say, “Gold standard is stool.” It's not impossible to get it done. You just have to advocate. For a lot of people that are experiencing reflux, and heartburn, and burping, and belching, they're put on proton pump inhibitors, which in and of themselves have a lot of long-term health complications. I say this with respect, because we put everyone in the hospital on Protonix, which is a PPI. But the more I learned about how important stomach acid is, we're actually making it worse by putting people on these drugs long term.

Melanie Avalon: I cannot agree more. I've had that stool test and I've had-- Do they test for H. pylori when they do endoscopies? 

Cynthia Thurlow: Yeah, they can do little samples and send them off. And obviously, that's up close and personal. Think about it in the hierarchy of costs, it's much more cost effective to do a stool test versus an invasive procedure. But sometimes, you need the invasive procedure. If they're in there, they can do a biopsy or testing.

Melanie Avalon: Yeah. Awesome. All right, shall we go on to our next question? 

Cynthia Thurlow: Sure. This is from Leah. Subject is: “Coffee differences.” “Hello, I wrote before with a question, but now, I have another one. I'm listening to an episode, where a listener asked about teeth whitening strips and it made me think of the time, Gin said, she had black coffee from McDonald's and it made her shaky. Now, I stopped getting flavored roast and only finished off my current stock of flavored roast during my window once I started fasting. My question is that besides the flavored roast, by flavored, things like hazelnut, toffee, winter mint, etc., how would we who are still relatively new to IF know if black coffee effects are fast in a bad way like McDonald's did for Gin? I buy whole bean coffee from Gobena, a not-for-profit that sends its proceeds to help orphans around the world and partners with adoptive families to help them fundraise and have been getting the Yirgacheffe light roast instead of the flavor roasted beans. I grind them at home and send about half of a five-pound bag overseas to my fiancé, who has also started fasting with me. He already liked his coffee black, so, no trouble there. What could have made that McDonald's coffee different? How could we find out? I want to fast clean, but the sheer relief. I could keep coffee even if I just stopped putting cacao in it during the fast was so nice. You gals will never run out of things to talk about on the podcast. We'll always have questions. Leah.”

Melanie Avalon: All right, Leah. Well, thank you so much for your question. I do remember when we were talking about this, and so, I looked up the McDonald's coffee and it is just coffee. There're no additives. I thought this was interesting. They say there's the potential of a dairy allergy. I'm guessing that's cross contamination from they're assuming with the coffee machine that it's possible that dairy could get into it. That's what I'm guessing rather than from the source. I don't know. It could be a few things. One, there's the whole movement of mold free coffee like the Bulletproof coffee with Dave Asprey. Do you drink coffee, Cynthia?

Cynthia Thurlow: I do not drink coffee. However, in our house, we have Purity and we have a company called Square Feet, and the latter of which is a very small like home-based business, but the man who runs it is very OCD about mycotoxins and tests multiple different ways. So, that's typically what we have in our house and what I generally recommend.

Melanie Avalon: Oh, nice. We will put links in the show notes to these coffees. The show notes by the way will be at ifpodcast.com/episode269. My coffee intake, I literally have a sip every morning. It's very, very small, but I drink Dave Asprey’s Bulletproof coffee because of the mycotoxins and mold issue. I've also used Ben Greenfield’s Kion coffee in the past. But people who react to these mycotoxins and mold, I think it can really be a thing. I think it could create that shaky affected people. So, it could be that. I don't know what else it would be. Do you have thoughts about it, Cynthia?

Cynthia Thurlow: Yeah, I think the concern about mycotoxins is a real issue, but I just can't imagine that McDonald's quality would be-- Who knows what else it's cross contaminated with. Could it have been blood sugar dysregulation, could have been a spike in cortisol? Because we know in some people coffee or whether it's the polyphenols, we know that you can get some appreciable cortisol dysregulation, which is going to raise your blood sugar, which is going to raise insulin. The shakiness could have been from a few different things. But certainly, quality is important. And so, it sounds Leah’s makes a very conscientious effort to select a product that sounds it's probably high quality. But I always think mycotoxins until proven otherwise, because coffee beans are readily known to be a mold sensitive or mold prone product, just like peanuts and legumes and things like that. So, that's probably where I would lean first. Yeah, I agree with you.

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Melanie Avalon: Okay. We have a question from Trina and the subject is: “Keto and OMAD,” one-meal-a-day question. Trina says, “I've been using OMAD for just under a week and have been doing okay. No weight loss yet, but I do have hunger pains periodically and some lasts for over an hour. I'm also doing keto while I'm having my one meal a day. Is this too much to do OMAD and keto at once and could this be causing me to feel hungry while I'm fasting? Or, should I stay the course or if I'm not going to lose weight, because I'm being too restrictive by using keto, should I add bread, pasta, etc., here and there? I do think I'd feel fuller at the moment, but I don't want the grains/carbs to spike my insulin. I've been keto since April 1st pretty strict and only up and down a few pounds weight loss, but overall, still the same weight. I did IF for 18:6 for a couple of weeks, no weight loss. Now, trying OMAD has been about a week. I maybe adrenal fatigued. Could this be my body healing instead of losing weight? If so, when oh when, can I hope to see any weight loss? I really do like the OMAD, but I'm getting frustrated. By the way, I eat in the middle of the day currently, but maybe shifting to an evening OMAD might help. I work full time, very busy, and was worried. I'd be dragging if I didn't eat in the middle of the day. But eating with my family would be more enjoyable for all of us.” And then she has a second question, but I thought we could answer this first.

Cynthia Thurlow: Yeah, there's a lot to unpack here. Unfortunately, the toxic diet culture has convinced women in particular that weight loss is the only metric to demonstrate if a new strategy is effective. If you look at the research typically, because women have different body fat to muscle mass composition, as well as hormonal fluctuations. I don't know how old Trina is. I don't know if she's insulin resistant. But depending on where you are life stage wise, it may take six to eight weeks to start seeing significant and when I mean significant, really one to two pounds a week over six, eight weeks, yes, I would expect to see some weight reduction. I think it's important to focus on non-scale victories. Meaning, are you getting changes in body composition, are your clothes fitting a little more loosely, are you having more energy, more mental clarity, etc.? I think there's a couple things to focus on. One meal a day for many people may not allow you to get enough macros in. I know this is something that Melanie and I have talked a lot about outside of the podcast. There's a lot of layers to this question. Obviously, the first one being be patient. I know it's easier said than done, of course. But I think that it's important to understand that you may not see a scale shift immediately and to just trust the course. 

The other thing is, can you get enough protein in one meal a day? That's always my concern with women. If you really just have one meal, are you getting enough food in? You also mentioned being adrenal fatigued and so, there's a lot to look at. When women are fasting, I think it's really, critically important that you focus on what's your sleep quality like. That's foundational. If you can't sleep through the night, your sleep quality is eroded, you need to back off on fasting. Number two, what's your stress management like? That's not three minutes of meditation once a week. Anti-inflammatory nutrition, I think keto can be helpful. However, maybe you need to really be thinking thoughtfully about what's working for your body. Protein, non-starchy vegetables, right types of fats. Then the last thing that I think about is, I don't know if you're exercising. It sounds like you've got a very busy schedule. But we know that insulin resistance starts in our muscles as an example. Some type of physical activity is going to be very important to help with insulin sensitivity. But it's hard for me to completely provide some perspective about the adrenal fatigue. If you're in perimenopause or menopause, more than likely your adrenals need some love and support and that's why the stress management and sleep are so important and the right types of exercise and food. Melanie, what would you add to that?

Melanie Avalon: That was very comprehensive. That was wonderful. The only thing I would add would be, so going back to the keto, I think there's this binary dichotomy that people have viewing keto, where they're either keto or they're eating bread and pasta, where I think it's much more nuanced than that. Adding carbs to keto doesn't have to be bread and pasta. It doesn't have to be this huge whack of high GI, potentially inflammatory carb source. You can add in some carbs while still existing more within a “keto paradigm.” A lot of people on keto do include berries, for example like small amounts of berries. Even upping the vegetable intake could potentially up the carb count. I would not go to bread and pasta to make yourself less stressed or less restrictive. I don't think for most people that that would be the solution. Some other thoughts about existing within the keto paradigm and frame, Cynthia mentioned this, but the role of protein is so important. I don't know if you're doing a super high fat version of keto or not, but adding that more protein and maybe if you are doing super high fat, titrating down the fat, that might be a way to A, feel more full because the protein is going to do that. B, more nourished via the protein and potentially encourage weight loss by titrating down the fat. 

Also, switching out the types of fats might be helpful. Depending on what type of fat you're having in your keto diet, MCT oil, for example, is a very thermogenic fat. If you are adding oils or butter, or things like that switching some of that out for MCT oil might have a beneficial effect on your weight loss. There is the option because you're worried about keto plus fasting being too stressful. There is the option of trying fasting with not keto. That is an option. Trying a higher carb, lower fat approach, for me personally that works really well. Again, we're all individual. When did she start this? Only a couple of weeks. Okay. I wouldn't jump to this right now, because like Cynthia said, it's only been a couple of weeks and I would stick it out a little bit longer. That said, if you make it months, and you're still not happy, and you're not seeing weight loss, some people do find that they do better on a higher carb, lower fat approach with the fasting. So, that is definitely something to try. 

Cynthia Thurlow: Well, It's interesting. When I talked to Sara Gottfried a few weeks ago, one of the things she was talking about is, women have to use keto differently than men. It's been my experience that men seem to be able to eat copious amounts of both plant-based and animal-based fats. We really have to reflect on the fact that carbs and protein are four calories per gram, even though I don't encourage people to count calories. Let me just put that in there. Whereas fats are nine calories per gram. You don't need as much fat as you think you do. As an example, if you're having a piece of salmon steak or a ribeye, guess what the fats are already in there. You don't need to add more fats. This is where I see a lot of women get into trouble, because dairy, cheese, cheese is delicious and nuts are delicious. And so, people are like, “Yay, I'm doing keto. This is awesome.” Before they know that they've eaten four portions of cheese, and three have nuts, and they've blown, any caloric deficit that might have even been created by intermittent fasting. So, just something to think about that plant-based fats for a lot of people including myself. I tend to do better with those, so less heavy fats, but really leaning into where you life stage wise, are you insulin resistant, and maybe being really mindful about your portion sizes of fats.

Melanie Avalon: Three thoughts to that. I'm glad you mentioned Sara Gottfried because I was going to bring her up in my answer because I was going to say that her, and you, and Dr. Anna Cabeca, all of you guys are really wonderful in talking about the nuances of keto for women specifically and how that might need to be adapted for women. I think that's really valuable. Cynthia's book, Intermittent Fasting Transformation, Dr. Gottfried’s-- What is Dr. Gottfried’s most recent book?

Cynthia Thurlow: Women, Food, and Hormones. 

Melanie Avalon: Wait. Straight to the point. 

Cynthia Thurlow: Yeah, Women, Food, and Hormones.

Melanie Avalon: So, if that title doesn't just say it. Dr. Anna-- What's Dr. Anna Cabeca’s most recent book?

Cynthia Thurlow: MenuPause. So, it's like M-E-N-U-pause.

Melanie Avalon: I actually haven't read-- I think that's her only book I haven't read. 

Cynthia Thurlow: It's beautiful. The photos, and the recipes, and she really did a nice very thoughtful, very, very thoughtful job. Yeah, it's a beautiful book. The photography is so pretty. We think about we eat with our eyes. And so, I told her, I was like, “Oh my gosh, the book is so beautiful.” If you do nothing else, it's artwork just to look at.

Melanie Avalon: I'm going to have to check it out. That's amazing. Well, we'll put links to all of those books in the show notes. The other thought I had was, again, listening to Peter Attia last night, one of the episodes I was listening to was, he was talking about people not losing weight on keto. He said, the first thing, if that's the case is he suggests titrating down the fat, which is just to echo what we both just said, Oh, yeah. The third thing is, I'm so glad you brought this up, because I think about this a lot. I think because we do live in such-- especially with the keto movement and this idea that has to be super high fat, we just have this feeling that with all of our food, we need to cook it in fat, and add all these oils, and you don't have to. Especially, if you're talking about salmon, salmon has a lot of fat in it. A not lean chicken breast, chicken thighs or chicken breasts with skin, that has fat in it. Steak has fat in it. So, you don't necessarily have to add a ton of fat. I know there are people like, is it Dr. Gundry, who says he pours olive oil by [laughs] a liter?

Cynthia Thurlow: I think about it. He's a dude. I always say like, “That's the one thing we--" Bio-individuality rules, but I don't see a lot of women that can eat copious amounts of fat. The worst thing is when someone says, “Oh, my God, I did keto and it was great until I gained 10 pounds.” It's almost always because they didn't realize how calorically dense fats are. I always say like, “If a little bit is good, too much is not good.” I will fully disclose that my favorite healthy fat, I love macadamia nuts. I have to portion out a quarter cup because they're so easy to overeat. I literally take the bag out, take my measuring cup out-- I don't measure my food otherwise. Take my measuring cup out, put in a bowl, put the bag away, and I'm like, “I'm done.” Because it's like kryptonite, it’s very easy to overeat fats.

Melanie Avalon: Nuts are a gateway food for me. I've said this on the show a lot. I don't know if I've said this to you. But one of the biggest epiphanies I had with all of this was, people will say that on keto, for example, that you can have unlimited fats, because they don't raise insulin. But the reason they don't really raise insulin is because they don't really need insulin to get stored. The ironic thing is, the same concept of fats not releasing insulin and the conclusion you could draw could be one of two things that are complete opposites. The conclusion that most people draw is, “Well, no insulin. So, it's not going to get stored. I can have all the fat I want.” But really no insulin, because it's so easily stored. So, just something to ponder.

Cynthia Thurlow: It's interesting. Ben Azadi always says, “You want to burn endogenous fat before you consume exogenous fat,” which means all of us have plenty of fat just to burn off. We want to burn the fat in our bodies as opposed to ingesting lots of fat. When we're thinking about evolved keto, meaning, as Melanie just said, people say, “Oh, I've no blood sugar spikes on my CGM.” It's understanding because you make it very easy for that extra energy just to get stored as fat. And so, we want to burn the fat inside before eating copious amounts of exogenous or external sources of fats as delicious as they are.

Melanie Avalon: I'll put a link in the show notes to that Peter Attia episode because it was his AMA #22.

Cynthia Thurlow: I love his AMAs. 

Melanie Avalon: Me, too. The title is Losing fat and gaining fat and it was all about the concept of fat flex, and how does fat actually go in and out of cells, and how does keto affect that. So, be very helpful for people. Trina had one last quick question. She said, “Also, do we count our fasting from beginning of eating window to the next beginning of the eating window or do we count it from where we end our eating? I'm getting confused on the whole 22:2 or 23:1, and where the hours are counted from. Thanks for all you do and I appreciate your time.”

Cynthia Thurlow: I always count it from when you stopped eating. 

Melanie Avalon: Yes. 

Cynthia Thurlow: It's interesting because I'm running a fasting group right now and there were two or three women that were struggling because they were thinking about it too much. I just said, “Whenever you stop eating is when your fasting window starts and that's the easiest way to think about it. Don't overthink it.”

Melanie Avalon: People get really caught up because when you end your meal, you're fasting but you're not in the fasted state. It can be confusing. If Cynthia said, if you're overthinking it, but don't overthink it. You are fasting and that's what you're counting. So, fasting is when you're not eating. 

Cynthia Thurlow: Yeah. I tell people it really takes about 12 hours for your body to get to a point where it's burned off or working through that last meal. It's important to not stress yourself out, because I tell everyone, I'm like, “We're so hard on ourselves, we endeavor to integrate these new strategies to make ourselves healthier.” Then next thing I know people are down a rabbit hole stressing and I'm like, “Listen, no stress. There's no stress.” When you stop eating is the beginning of your fasting window until you eat again.

Melanie Avalon: Here's a question for you that we've often discussed on this show and I'm always curious what people’s thoughts are. If you're doing a time approach where it's a 16:8 or something like that, would you rather count the fasting hours or the eating hours? I can clarify more if you need me to clarify. So, Gin, for example, likes to have a four- or five-hour eating window, whereas I like to have minimum fasting hours. I like to count the fasting hours.

Cynthia Thurlow: I count the fasting hours. I really lean into how I feel in terms of-- Because I have a wider eating window. That's one way I can get in the amount of protein that I need every day. For me, I really reflect on what my minimum fasting hours should be and that's usually what I work from.

Melanie Avalon: Same. It's exactly what I do.

Cynthia Thurlow: Yeah. I'm checking myself like, “When I stop eating last night?” Last night, I went out to dinner with my 16-year-old, so, I ate a little later than I normally do which is okay. Yeah, I usually focus on, “Okay, how do I need to adjust my fasting windows to make sure I'm at least hitting that minimum for me?”

Melanie Avalon: Same. What I don't like is, I don't like the thought of having to close my eating window at a certain time. Once I start eating now, I have this amount of time to eat that I find that very stressful.

Cynthia Thurlow: When do you open up your feeding window, because I know you stay up a little later than I do? 

Melanie Avalon: Like nine. 

Cynthia Thurlow: That's hilarious. For listeners, I know, you know that Melanie stays up a little later and I go to bed a whole lot earlier. But I was thinking one day, I was like, “I wonder what time she starts eating,” because I know what time I start eating and they might be like 12 hours apart. [laughs] 

Melanie Avalon: It's very possible. The only time I eat earlier is if I'm getting dinner out. I've been doing it for so long, too.

Cynthia Thurlow: That's what we're-- This is really leaning into what works for you and your body. If I eat at 9 o'clock at night, my sleep would be a disaster. [laughs] But I also go to bed a lot earlier. So, I think last night I was up late. My Oura was like, “You stayed up till 10:15.”

Melanie Avalon: Oh, I would be so proud of myself if I went to bed at 10:15. I would be so proud of myself if I got up when you get up, too.

Cynthia Thurlow: Yeah, well, it's funny. My Oura was squawking at me last night that it wants me in bed between 8:30 and 9:30 and I'm like, “Oh.” Sometimes, I just don't want to go to bed that early. And then it squawks at me, because my sleep latency is two to three minutes because I take progesterone which is sedating and helps me fall asleep. So, I just say I'm not going to worry about the sleep latency. I know why I fall asleep quickly.

Melanie Avalon: Yeah, I think I've said this before, but I I've hit up ceiling on my Oura Ring. I don't think I can get better than a certain score that I received. I don't think I can get higher than 90, because of how late I go to bed. Even if everything else is great, it considers that a problem, even though it tells me to go to bed late. It's ironic. Well, this has been absolutely wonderful. I want to just keep answering questions, but I guess, we'll have to wait till next week. So, a few things for listeners before we go. If you would like to submit your own questions for the show, directly emailquestions@ifpodcast.com or you can go to ifpodcast.com and submit questions there. I will say, Cynthia, we've been getting because you weren't here before you were here. There's definitely been an influx in questions and Cynthia has come onboard and it's really exciting. I think people are really excited to get your perspective on things. So, keep the questions coming. The show notes again will be at ifpodcast.com/episode269 and you can follow us on Instagram. I am @melanieavalon. Okay, wait. Let me try. Cynthia is @cynthia_thurlow_.

Cynthia Thurlow: Yes. Just to make it complicated. 

Melanie Avalon: Yes. I think that's all the things. Anything from you, Cynthia, before we go?

Cynthia Thurlow: No, I'm loving all the questions. In fact, as Melanie stated, we have an influx of questions and we're just trying to diligently hit a couple every episode. So, keep them coming and I've been encouraging people that have been asking questions in my DMs across social media to email them to us, so we can answer them on air.

Melanie Avalon: Yeah, definitely. Because people will DM me as well. But if you want it on the show, the email is where it needs to be. That's how it goes through the system to potentially get into the lineup. So, all right, well, this has been absolutely wonderful. Happy Memorial Day weekend.

Cynthia Thurlow: Thanks. To you, as well. 

Melanie Avalon: I will see you next week. 

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and recomposed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Oct 03

Episode 233: Melanie’s Zoe Experience, Glucose Highs & Lows, Amenorrhea, Fasting & Menstruation, Lethargy After Eating, Chronotypes, High Cholesterol, Prediabetes, And More!

Intermittent Fasting

Welcome to Episode 233 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Gin Stephens, author of Delay, Don't Deny: Living An Intermittent Fasting Lifestyle

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At MelanieAvalon.com/beautycounter, And Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: melanieavalon.com/beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

For A Limited Time Go To drinklmnt.com/ifpodcast To Get A Sample Pack For Only The Price Of Shipping!!

Listener Q&A: Melanie - Fasted Blood Donation

Listener Q&A: Jess - Where's My Period?

Women and Fasting: Does Fasting Affect Your Cycle?

Listener Q&A: Kim - Lethargic After Breaking Fast

The Power of When: Discover Your Chronotype - and the Best Time to Eat Lunch, Ask for a Raise, Have Sex, Write a Novel, Take Your Meds, and More (Michael Breus)

Chronotype Quiz

Listener Q&A: Megan - Question For A Friend Who Is At A Healthy Weight But Has High Cholesterol And Is Pre-Diabetic

Effects of Intermittent Fasting on Health, Aging, and Disease

Clinical Management of Intermittent Fasting in Patients with Diabetes Mellitus

Stay Up To Date With All The News And Pre-Order Info About Melanie's New Serrapeptase Supplement At melanieavalon.com/serrapeptase!

TRANSCRIPT

Melanie Avalon: Welcome to Episode 233 of the Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Gin Stephens, author of Fast. Feast. Repeat.: The Comprehensive Guide to Delay, Don't Deny Intermittent Fasting. For more on us, check out ifpodcast.com, melanieavalon.com, and ginstephens.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment. So, pour yourself a cup of black coffee, a mug of tea, or even a glass of wine, if it's that time, and get ready for The Intermittent Fasting Podcast.

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And one more thing before we jump in. Are you fasting clean inside and out? Did you know that one of our largest exposures to toxic compounds, including endocrine disrupters which mess with our hormones, obesogens which literally cause our body to store and gain weight, as well as carcinogens linked to cancer is actually through our skincare? Europe has banned thousands of these compounds for being toxic, and the US has only banned around 10. It's honestly shocking. So, when you're putting on your conventional skincare and makeup, you're likely putting toxic compounds directly into your body. These compounds can make you feel bad, can make it really hard to lose weight, can affect your hormones, your mood, your health. And ladies, if you're thinking of having kids, when you have a child, these compounds actually go directly through the placenta into the newborn. That means your skincare and makeup that you're putting on today actually affects the health of future generations. Did you know that conventional lipstick for example often tests high for lead, and the half-life of lead can be up to 30 years in your bones? That means when you put on your lipstick, 30 years later, half of that lead might still be in your body.

Thankfully, there's an easy, easy solution to this. There's a company called Beautycounter and they were founded on a mission to change this. Every single ingredient in their products is extensively tested to be safe for your skin, you can actually feel good about what you put on. And on top of that, their products actually work. That's because they're not “all natural.” They actually combine the best of both worlds, both synthetic and natural ingredients, to create products that actually support the health of your skin and make your skin look amazing. They have skincare lines for all your skin types, deodorant, shampoo and conditioner that I love, antiaging and brightening peels and vitamin C serums, and incredible makeup. If you see my makeup on Instagram, that's all Beautycounter. You can shop with us at melanieavalon.com/beautycounter.

And if you're thinking of making safe skincare a part of your future, like we have, we definitely suggest becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership, totally completely worth it. Also, definitely join my clean beauty email list at melanieavalon.com/cleanbeauty, I give away a lot of free things on that list and join me on my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. I do a weekly giveaway every single week for Beautycounter, people share their experience and product reviews, and so much more. And again, the link to shop with us is melanieavalon.com/beautycounter. All right, now enjoy the show.

Hi everybody and welcome. This is episode number 233 of the Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Gin Stephens.

Gin Stephens: Hi everybody.

Melanie Avalon: How are you today, Gin?

Gin Stephens: Doing great. How about you? [laughs]

Melanie Avalon: I'm good. I have ZOE updates.

Gin Stephens: Very cool. I've also been just wearing the-- What is it?

Melanie Avalon: CGM?

Gin Stephens: Yeah, the CGM from, I was trying to think of the company--

Melanie Avalon: Levels.



Gin Stephens: Levels. Yeah, I couldn't think of Levels. I could think of a CGM, but I couldn't think of Levels. I've been wearing the CGM from Levels. Man, it's so interesting.

Melanie Avalon: What have you learned? What have you found?

Gin Stephens: Well, I can absolutely feel when my blood sugar goes down during the fast.

Melanie Avalon: Crashes.

Gin Stephens: Not crashes. I wouldn't call it crashing. It doesn't ever feel like it crashes but I can absolutely feel when my blood sugar gets down into the 70s. I wake up in the morning, I drink my coffee, my blood sugar sticks around in a certain range. And then around 1 to 2 o'clock, I have a wave of hunger. And that is exactly when my blood sugar goes down into the 70s.

Melanie Avalon: That's interesting.

Gin Stephens: Yeah. It's not hunger that's shaky hunger. It's really easy to ignore. Any intermittent faster are out there has felt that before, but I just ignore it. And then, for the entire rest of the time that I'm fasting, I stay very solidly in the 70s. It doesn't go up and down a lot after I get that shift. It's like I can feel the metabolic switch, and then my body is just well fueled, and my blood sugar stays very constant. It's fascinating.

When I did ZOE, I had longer windows, the muffin day and all of that. Also, I was using the little-- it was different versus the way Levels does with syncing with your phone. It wasn't as easy to really see the data when I did ZOE. But with Levels, it's just been fascinating. I can just go in the fasted state and stick right there in the 70s.

And then, it's also fascinating to see what I eat, and how my blood glucose responds. One night I opened with-- Well, it was higher carb, but low fat. I ended up just-- I didn’t mean to, it just happened to be the meal that I had that night, ended up being a very high carb, low fat, not a lot of protein. My blood sugar went crazy. It went up so high. I can't remember the exact number, but the spike was like oop. As long as I eat a mixed meal, fat, carbs, protein, it's steady. I have a biphasic response, which I read on Levels is a good thing. One little raise, then down, then up and down again. But fascinating. I've got to have sufficient protein and fat along with carbs to keep it steady. I knew that, but it's good to see it.

Melanie Avalon: Is this your first time wearing it with Levels, like a company that lets you see it all?

Gin Stephens: Yes.

Melanie Avalon: So, now you understand my obsession?

Gin Stephens: Well, and then I actually took it off [laughs] because I was like, “Alright, that's enough.” I took it off. I didn't need to see it for long.

Melanie Avalon: Oh, how long?

Gin Stephens: I don't know. Not that long, but it was enough. A week maybe, it was enough for me to really see. I'm so in tune with how I feel that none of it surprised me, but it was so interesting to see it.

Melanie Avalon: Another question. Do you see the intense morning spike?

Gin Stephens: I wouldn't call it intense. No.

Melanie Avalon: Just because I know we get a lot of questions from listeners about high morning blood sugar and when I wear mine, mine spike's to about 120.

Gin Stephens: Oh, yeah, mind doesn't do that. Oh gosh, no. I never get out of the 90s until after my windows open.

Melanie Avalon: Interesting.

Gin Stephens: Yeah, I'm always in the-- overnight, it does different things. And that was one reason I took it off just from the sleeping and I also was getting a massage the next day. I was like, “A massage therapist is going to have to work around this,” because I got a massage when I was wearing it for ZOE and she couldn't really work on that arm very well. So, I took it off. I mean, it was not a big deal. I learned what I needed to learn, basically. But, yeah, my blood glucose stays around in the 90s all throughout the morning with my coffee. Down into the 80s some, up into the 90s. But it never went over 100, unless it was right after I'd just eaten.

Melanie Avalon: Mine goes up every morning, but then it goes down consistently. What's interesting is I'm the exact opposite of you. I feel hungry when I get those spikes, and then when it starts going down is when my hunger kind of goes down.

Gin Stephens: Well, I get the hunger, I think, right when it hits the down, and then the hunger wave is gone and it stays down. It's just fascinating to see. Again, I learned from ZOE that I don't have a great blood glucose response to too much blood glucose at one time, which I proved with that meal. The ZOE data, when I would get scores for the meals, the ones that gave me a good score were the ones that were a combination of carbs with sufficient fat.

Melanie Avalon: And my comment about that, I'm just so excited about all of this, just for listeners, I think an important takeaway, because they might hear that and think that for them, that's what would work best but we're all different. For me, I'm the best when I do high carb, low fat, but if I combine, then it does not do well on my CGM.

Gin Stephens: If you have high carb, low fat, your blood sugar is great?

Melanie Avalon: If I do high carb, low fat, it spikes after the meal which is anticipated normal.

Gin Stephens: How much does it spike?

Melanie Avalon: It really depends on the night, but before eating, it'll be in the 80s. And then a low spike, it might be like 120 or a high spike it might go to 140.

Gin Stephens: Okay, see, mine went to 172. That day, I had low fat by accident, and I didn't realize that till I went back and looked at the meal. It was rice and dates and carrots and kale. I didn't add anything to it. It didn't have any beans, it didn't have very much fat at all. My blood sugar went berserk. But even the next night, I had a blueberry biscuit. It was not the least but low carb or low fat and my blood sugar was beautiful. It's fascinating. Now with ZOE, I learned that I can't have too much fat, that backs up to, I don't clear fat quickly. So really, for me, I should not over consume. If I eat too much food, that was when my ZOE score would go down using their data. I would have a beautiful meal that would score in the 90s. And then, if I ate too much again too soon with too much fat, it would plummet my score.

Melanie Avalon: Well, you know what's interesting, I don't know if that would be the case if I did high carb low fat with starches. The times it has spiked, I had starches in it. The carbs I'm eating are all from fruit. But, yeah, it doesn't really go over 140 and then it goes down and then it stays down.

Gin Stephens: Mine were very starchy. But when I had very starchy carbs the other days with plenty of fat and also protein, I didn't have that huge spike.

Melanie Avalon: The thing I learned last night, I was actually thinking about it this morning looking at the CGM was, I usually drink a glass of wine every night, but if I drink more wine-- last night, I had a wine night with a friend on the phone and it was four hours. We drink a lot of wine over four hours. My blood sugar response is so much better if I have a big alcohol preload, and my theory is that it just completely depletes glycogen. That's my theory. There's been studies on wine and insulin sensitivity, so probably helps with that. But, yeah, probably my best blood sugar response is when I have more than a glass of wine before eating.

Gin Stephens: That's fascinating. It just shows we're so different. The next day, other than that one day where my blood sugar went crazy after the low fat, high carb meal, I would not say any of my meals were low carb at all like I said, and I had rice again, it wasn't like that's the only time I had rice. For me, it really seems to be that combination of the carbs, plus the fat, plus the protein keep me steady, and it makes sense when you think about how it flows, how it gets into your bloodstream, flows digestion.

Melanie Avalon: Gin, I haven't done the second day of muffins yet.

Gin Stephens: You're supposed to do on the next day.

Melanie Avalon: You don't have to. I've been chatting with the help people.

Gin Stephens: Okay. All right.

Melanie Avalon: I think it'll be more telling if I don't do them back-to-back. For listeners who are not familiar, ZOE is a program, scientific study.

Gin Stephens: It really is. It's a study, program, all of that.

Melanie Avalon: Because I've been making posts about it. I'm like, “What do I call it?” It's an experience, where you learn about yourself. In any case, it is created by Tim Spector. He's a professor of genetic epidemiology, but he's an expert in personalized medicine and the gut microbiome. And they also have doctors as well creating the program. Basically, what happens is you get these special created muffins that feature different calorie and macronutrient breakdowns, and you eat them and you do a certain amount of fasting after eating them. If you're in the study portion of it, which is optional, you're wearing a CGM, either way you do a finger prick blood test. And it evaluates how you process carbs and fat, and you also do a gut microbiome stool sample, which is really cool, but it's just so funny because-- and Gin already knows this, oh, my gosh, the muffin. So, people talk about the muffins how they don't taste very good. I was looking at the ingredients before taking it and I was like this is just going to light up every dopamine center in my brain. I just know it. And literally, it was like the most amazing thing I've ever tasted.

Gin Stephens: I've never heard anyone say that about the muffins, like ever, which is hilarious.

Melanie Avalon: I've been asking on my Facebook group, and there have been a few people like me, and it's all people who are really intense and don't eat processed foods ever. The birds were singing, I was like, “This feels like cocaine.” I mean, I don't know what cocaine feels like.

Gin Stephens: I was like, “This is disgusting.” I was so excited to have muffins, and these taste so bad. These are the most disappointing muffins. I guess that's the key that you have not had anything like that whereas I'm not interested in any of that because I want a good muffin.

Melanie Avalon: I did a poll on my Facebook group, and it was pretty clear. If you eat processed foods even just a little bit, then you're more likely to not like the muffins. If you don't eat processed foods, you're more likely to like the muffins. But then, the funny thing and this was so interesting, and I learned so much about it about myself and fasting, was you have to fast after the first set of muffins for four hours. Gin and I, we fast every single day. Those four hours were so difficult. Having fasting right after eating something that crashes your blood sugar is so hard.

Gin Stephens: That was the hardest part for me, too, the time in between, muffin meal one and it was muffin meal two. We had muffins again, yeah, that was the hardest of all, because I'm not used to being hungry in my eating window. Once I open my eating window, if I'm hungry, I eat something. I would never open my eating window if it was something weird, and then fight through terrible hunger for four hours.

Melanie Avalon: Yeah. It gave me so much empathy, because I think I forget-- because we get so many questions about people who are really nervous about starting fasting, and they think they're going to be miserably hungry, and it's just nice to remember, oh, this is the baseline that they're probably coming from. They're used to eating and then it being really, really hard to fast. If they're thinking fasting is like that, fasting would be really miserable. It definitely took me back to my pre-fasting days and made me so grateful that I am not living like that, from blood sugar swing to blood sugar swing. And then, you're supposed to do a second day but I was like, “I can't do these two days in a row.” They said I could do it a different day, and I do think that'll be more telling because it'll give me more time to really be at baseline. I'll be coming from my true self with my blood sugar response, I think. But interviewing Tim was amazing.

Gin Stephens: You see why I love him so much.

Melanie Avalon: Yeah. He was so intelligent and kind and very nuanced. I asked him a lot of questions because a lot of our audience is low carb or keto. We've been getting some feedback that sometimes people don't tolerate fat so well. So, the impression that might be given from the app is that they need to go low fat, which makes sense. But I've been thinking that maybe if they don't process fats, well, ironically, that low carb might be a better approach, which would ironically be high fat. I was able to talk to him about all of that. He agreed, and he said that basically right now the way it's set up-- he said ideally he wants to have another arm of it that is tailored towards keto people, because I also asked about the false-- I don't know if we have false positive or false negative. People who are doing a low carb diet, when they do the muffins, they might have a temporary insulin resistance that is created from having been low carb, which is temporary, but I think that could skew the results. He was saying that they've been thinking about that and do they need to tell people who are doing low carb to do a few days before of higher carbs? Or should they have an arm of it that's low carb? It was a really, really nice discussion, and I walked away from it--

Before, I was a little bit-- I don't know if I was skeptical, but I was curious about things I've been hearing from my audience but now I feel pretty good. I'm really encouraging listeners to do it because he says they really need to get a lot of people to do it so that they can continue to learn and then in the future, maybe expand it to do things like that.

Gin Stephens: Yeah. That's why I'm such a fan of him. Just when you read his books, which you've read them, when you read his books, you realize, “Okay, this guy's impressive.” And then you see the work they're doing with the PREDICT studies, and you're like, “Okay, this is amazing,” and it's new, and then they're changing. What you're going through is a little different than when I did it whenever that was last year. They're constantly evolving, which science is supposed to do, that's what scientists do. But you said that you felt it was steering people towards low fat, mine absolutely did not steer me towards low fat. I got higher scores when I combined carbs and fat, but it was just if I kept eating more fat, then the score would go down. It was when I overdid the fat. If I had, I don't know, let's just say a piece of whole grain toast, my score would be low. But if I put an egg on top and some avocado, my score would go up, and it would be higher. You haven't gotten to that point yet.

Melanie Avalon: Yeah. I'm just going off of what people have said in my group and I haven't received any information yet. So, I can't really speak. I don't know what it looks like the scores.

Gin Stephens: It absolutely did not steer me to low fat. But it did, because my scores would go up as I would add fat, but then there would come a point that it was too much fat and the score would go down.

Melanie Avalon: I'm really curious to see what mine is. And also, oh my gosh, the blood finger prick.

Gin Stephens: That was intense.

Melanie Avalon: I prick my finger all the time, because I check my blood glucose with a glucometer often. So, I was thinking the lancet was-- I was thinking it was like the one I normally use, which is like a really, really tiny prick.

Gin Stephens: Yeah, I told you it was different.

Melanie Avalon: You had said it was hard for you, and I'd asked in my group and people had said it was difficult. I was like, “Well, I better just really jab this thing into my finger.” And I didn't realize it's a different lancet that is made to get a lot of blood out. I mean, blood was spewing everywhere. I was like, “What if I faint?” [laughs] For a second, I literally was like, “What if it just keeps bleeding?”

Gin Stephens: So, you really went for it?

Melanie Avalon: Yeah. So, it was not a problem filling that card.

Gin Stephens: Yeah, I was like squeezing, squeezing, squeezing, trying to get it all out. But I did, but it was not flowing.

Melanie Avalon: I was doing it at 2 AM. [laughs] So, yeah, it's been a really cool experience. The feedback has been mixed, for sure, in my group, but a lot of people have said that it's been interestingly game changing for them to lose weight.

Gin Stephens: Yeah, I've heard that too. I interviewed someone for Intermittent Fasting Stories, who shares her story. I don't know when her episode comes out, Christie Osborne, but it was game changing for her. It's just a matter of, not everyone likes what they find out. I've also heard that people were mad about what they found out. I'm like, “Well you can't be mad that you don't like what you learn.” I don't like to know that my body doesn't clear glucose quickly or fat quickly. I'm not thrilled, but it's not their fault. They just shared that with me, or whatever is in my gut microbiome, knowledge is power and once you know, then you're equipped to deal with it.

Melanie Avalon: Yeah. Day two of muffins, I'm doing Tuesday.

Gin Stephens: Well, enjoy.

Melanie Avalon: Thank you.

Gin Stephens: I don’t know if y'all can hear somebody out is outside doing like a weed eat or blower, so if you hear something that sounds like equipment, that's what it is.

Melanie Avalon: Oh, I can't hear it.

Gin Stephens: Good. It's the weekend and neighbors are doing their yard work. Or it could be Chad, I don't know. Someone's out there doing yard work.

Melanie Avalon: It sounds good.

Gin Stephens: Okay, good.

Melanie Avalon: And then one last thing, just a quick announcement for listeners. Well, I'm going to be interviewing Robb Wolf on this show. I am so excited. You guys know I'm such a Robb Wolf fan girl. So, this will be my third time interviewing him, which is very nice. He is the force behind The Paleo Solution, which is the reason that I started the paleo diet. He also wrote Wired to Eat, which appropriately enough is about people's individual blood sugar response to carbs. That's the main thing it's about. And then he wrote Sacred Cow about regenerative agriculture. And he's also one of the creators of LMNT electrolytes, which we talked about all the time on the show, which our listeners love. By the way, you can get a free sample pack at drinklmnt.com. That's LMNT dotcom slash ifpodcast.

He's going to come on the show, and I'm trying to decide if I'm going to make it just me interviewing him. But I think I'd like to include listener questions. So, if you have any questions about electrolytes while fasting, now is the time, email those. Also, if you want to ask him anything else, feel free to email as well.

Gin Stephens: Do it quickly because you only have like a week before-- and I'm actually not going to be on that interview. I've got something going on that day. And also, it's so much easier to interview with one person instead of two people trying to interfere. So, Melanie's going to handle that one without me, but get the questions in.

Melanie Avalon: Yes. Email them right now. Anything fasting, electrolytes, regenerative agriculture, or if you just want to ask Robb something.

Gin Stephens: Hi, everybody. I want to take a minute to tell you about Prep Dish and what they have going on for you this summer. Summer is my favorite season, and I'm sure that you've heard me say that before. But one thing about summer is that we are busy. That's why I'm so excited to tell you about the free Bonus Menu Prep Dish is offering this month, and it's only good through the end of June. If you're a regular listener, I'm sure you're familiar with their new Super Fast Menus. If you thought prepping five healthy dinners in just an hour was the best it could get somehow, they're upping their game. Just for the month of June, Prep Dish is offering all new subscribers a free bonus menu. It's not just your average meal plan though. It's designed to let you prep five healthy dinners in just 30 minutes. It seriously doesn't get any easier than that.

Don't worry, just because the meals come together quickly, that doesn't mean you'll be missing out on flavor. The Bonus Menu includes things like California burgers with berry salad, shrimp tostadas, and a slow cooker Italian pork. When you subscribe, you'll have access to the gluten-free, paleo, keto and the Super Fast menu, in addition to the Bonus Menu. If you're still not convinced, remember that you get a two-week free trial if you go to prepdish.com/ifpodcast so you can try the meals out yourself before you commit. Again, that's prepdish.com/ifpodcast for two weeks free, and for the month of June anyone who signs up gets the fastest meal plan ever bonus. Now, back to the show.

Melanie Avalon: Shall we go to some of our listener questions?

Gin Stephens: Absolutely.

Melanie Avalon: The first thing is actually some listener feedback, and it comes from another Melanie. Oh, my goodness. The subject is “Fasted blood donation,” and Melanie says, “Hey, ladies, I am a regular podcast listener to all of your shows. Thank you for all of your very useful information and easy to apply tips and tricks. I was just listening to Episode 229, and the question came up about blood donating fasted. I'm an RN and a hematology-oncology clinic. We give lots of patients lots of blood. Thank you to all of those wanting to and able to donate blood. Since COVID, there has been a sharp decrease in the blood supply and every unit helps.

I've been an intermittent faster for four years and I've been donating blood for many years. I've never had any issues with donating, so I donate fasted. I do drink a large amount of water throughout the day to keep from getting dehydrated, and therefore preventing low blood pressure. I also make sure to eat a very good meal when my regularly scheduled window opens. All that being said, that is what works for me. I would not recommend a new intermittent faster donate fasted or a new donor to donate fasted. I hope this helps and maybe it will encourage others to donate blood even if it means they open their windows a little early. Happy fasting, Melanie."

Gin Stephens: Awesome. It's always good to hear straight from the expert.

Melanie Avalon: I really liked what Melanie said. We didn't really touch on this last time about how appreciated it is for people to donate blood. But it sounds like if you're new to donating blood, probably don't do it fasted the first time, maybe do it at least once not fasted. I would just faint either way. Shall we go into our questions?

Gin Stephens: Yes.

Melanie Avalon: All right. We have a question from Jess. The subject is, “Where's my period?” Jess says, “Hello, ladies. I recently discovered your podcast and binged three episodes in one go on a long walk. I love it. Thank you for all you do. I started IF at the end of last year and followed a 16:8 rhythm for about six months. I would eat breakfast at 10:00, lunch around midday and dinner at 6:00. This worked really well for me. I lost weight, felt healthy, had so much more free time in the evenings and never felt hungry. About a month ago, I decided to try extending my fast to 18 hours and now eat two meals a day at around midday and between 6:00 to 7:00 PM. I've continued to see results and feel good. A little hungry in the run up to lunch, but I'm getting used to it.

This month, my period arrived on time, but it was extremely light and then gone the next day. I haven't changed anything else in my routine. My diet is the same, usual amount of exercise and sleep. I have suffered with PCOS for around six years. But since coming off the pill two years and two months ago, I've actually still had a regular cycle, my period is always between four and seven days. I've told myself to chill because it's only one month and I might be back to normal next month. But I am worried because I'm hoping to start a family next year and don't want to be causing any unseen damage. After a bit of googling, I've seen a few articles linking disrupted menstruation with IF, and wondered if you had any insights. The two might not be linked at all, it's just that the extension of my fast is the only change I've made recently. I consider my diet to be healthy, I would label it as low carb, high fat and mostly organic. Hope you can help, and thanks again for your wonderful work. I don't use Facebook. So, I'm unable to join your groups. However, I'm now a very happy subscriber of the podcast and look forward to going back through the library of episodes. Jess.”

Gin Stephens: Jess, thank you for asking that question. You're right. You can find a lot of stuff when you're googling that talks about disrupting menstruation with women. I think it's really key to keep in mind that we know that over-restrictive dieting in general affects women's cycles. Are there women who do intermittent fasting in an overly restricted way? Yes. Would that be likely to lead to menstrual disruptions? Yes. It doesn't sound like you are doing an overly restrictive approach however, because 18 hours is really not extensive. Now, if you had just gone to 23:1 and you eating a one-hour window, that might be a too much restriction. But it sounds like you're eating two meals a day in an 18-hour fast with a 6-hour eating window, I would not think that you're overly restrictive. You haven't missed a period, so I wouldn't be too worried right now. If you start missing periods, then I would go see your doctors, get your hormones checked out, see what's going on with that because it's hard for us to know. I mean, maybe you're eating two really tiny meals. I don't know, for me a meal is substantial. I know it is for Melanie as well.

There's a great article, but it's a blog post that I want you to look for. If you google "women and fasting, does fasting affect your cycle," it's on The Fasting Method website. It talks about the experiences that they've had with women, and it's actually was written by Megan Ramos, although for some reason at the top, it says by Jason Fung, but this is clearly written by Megan Ramos. That says like, “Many of the women I've worked with, I was scared to fast at first without knowing how it affected my fertility.” It's clearly Megan Ramos wrote it even though it says Jason Fung at the top. Look for women and fasting, does fasting affect your cycle, and read that and see what Megan Ramos says about it, because they've worked with a lot of women in their practice. Spoiler alert, they find that often, at first, they'll see disruptions and then they'll find that women's cycles are actually more regular than they had been before. Again though, you're a study of one, so you'll only know by seeing what happens for you. It could be a coincidence. Going from 16 to 18 is not a big change. I would be really shocked that you've gone to over-restriction just with the two-hour increase in your fast. What do you think, Melanie?

Melanie Avalon: Yeah, I thought that was great. For listeners, we will put a link in the show notes to that article to make it easy to find, and the show notes are at ifpodcast.com/episode233. Yeah, I agree. I was going to say, it's hard to know, if it's just adjusting and changing, or if it's a sign that it actually is going away. I would give it a few more months and see what happens. And if it does go away-- I mean, it sounds like you were really happy with your earlier approach because she said she was on a 16:8, worked really well, she lost weight, she felt healthy, she had free time, she never felt hungry. If it does turn out to be a thing where your period goes away, I see nothing wrong with going back to what you were doing, which sounded like it was working really well. If you're worried about not getting quite as many benefits because of those extra two hours, I really wouldn't sweat it. I would do the pattern that is really working for you. So, yeah, I like what Gin said.

Gin Stephens: It's too soon to really know. You didn't skip your period like you said, it was just really light. Since Jess says she wants to start a family, I assume she's nowhere near the perimenopausal phase, because that's when everything starts to go wacky no matter what you're doing. [laughs] But I don't think that would be applying to Jess, but anybody who's in their 40s and beyond, get ready. [laughs] It's a bumpy ride.

Melanie Avalon: Goodness.

Gin Stephens: You'll see, yep.

Melanie Avalon: Feel free to let us know, Jess.

Gin Stephens: Oh, definitely. I would love to have a follow-up on that.

Melanie Avalon: Me too.

Gin Stephens: All right, so we have an email from Kim and the subject is “Lethargic after breaking fast.” Kim says, “Hi, Melanie, and Gin. Thank you so much for this podcast. You are both truly inspiring. I've lost 74 pounds after doing IVF for about a year.” And I just want to stop and say, amazing, Kim. That's fabulous.

Melanie Avalon: How many pounds, like, every-- 365?

Gin Stephens: I mean, a pound a week is “average.” So, 52 would be more typical. 74 is amazing.

Melanie Avalon: Wow.

Gin Stephens: Yeah. Kim goes on to say, “I am currently listening to Episode 84. So, I apologize if this question has been asked before. On occasion, I have noticed that if I break my fast a couple of hours early, I get completely lethargic like I desperately have to take a nap. I usually break my fast around 6:30 PM and close my window by 9:30 PM. However, I notice that if I broke my fast a couple of hours earlier, I get so tired. I, for the most part, eat whole foods and balance my meals with protein, vegetables, healthy fats and carbohydrates.” Me too, Kim, that sounds a lot like how I eat. “My question is what are some reasons as to why you would get so lethargic after breaking your fast. What are some ways to fix this? Thank you so much for what you do.”

Melanie Avalon: All right, Kim, great question. We have answered things like this before, but what 233 episodes, I thought we haven't answered this in a while. Obviously, there could be a lot of potential things going on, but two things are coming to mind for me personally. One of the reasons I personally love having an evening eating window is it does make me tired. During the day, I'm awake, I'm alert, I'm active, and then when I eat, that's my wine downtime, and the actual eating process tends to be a parasympathetic state, it's called rest and digest for a reason. So, it can be completely normal to get tired after eating. I think a reason that you might find yourself getting tired earlier, when you break fast earlier, when maybe in the past before fasting you didn't experience that would be because it's possible that you have conditioned your body with intermittent fasting, because you do have an evening window. Now, the signaling that your body is used to, is when you eat, that's you're wind down, go to bed, get ready for bed time. So, it's like an association that your body has made. Now when you eat earlier, it gets that started. Whereas in the past before you had this evening eating window, your body was actually used to eating earlier and so it was used to not getting “tired.” They're called-- how do you say it, zeitgebers?

Gin Stephens: Oh, I don't know. I don't know that word.

Melanie Avalon: Zeitgebers, I think. It's a German word. It means cues to your-- it's like using your environment that signal things to your biology. The definition is a rhythmically occurring natural phenomenon, which acts as a cue in the regulation of the body's circadian rhythms. Food and eating are very, very powerful zeitgebers. Light is another one. Basically, what has happened, I think, is that you have made food into a zeitgeber that tells your body to wind down. And so, now when you eat earlier, that happens. Another potential option or explanation behind this, is I've actually been diving really deep into Dr. Michael Breus’s work. He wrote The Power of When. And he's the one who came up with the chronotypes, like the dolphin, the lion, the wolf, and the bear, because I'm going to be interviewing him which is very exciting.

Gin Stephens: Very cool.

Melanie Avalon: Yeah, I'm so excited. And he has a new book coming out called Energize! which actually talks about the chronotypes for sleep combined with your metabolism type, if you're a fast, medium, or slow metabolism, that's a pretty cool book. He talks about how different chronotypes get tired naturally with their circadian rhythm during different times of the day. If you are a bear chronotype, which is the most common chronotype, it's actually very normal to need an afternoon nap. What I think might happen-- and I don't know, Kim, if you're a bear, but I think what might happen for people who are bears, for example, they would be used to needing a nap during the middle of the afternoon and then normal eating pattern that would probably be after they ate, that's just me theorizing. But if they switch to an intermittent fasting pattern where they're eating later, now they're going to be stimulated during the day, and they're going to be alert, and they're going to probably not get as tired during that time when they naturally would have a dip because they're not having the meal or the snack that is encouraging that. So, it could be that you actually naturally were getting tired during that time. But now you only realize it when you have something that really powerfully stimulates it, like eating. But if you're curious, you can take his chronotype quiz on his website. We can put a link to it in the show notes and you can figure out what chronotype you are.

Something I love about it is, I'm a dolphin, which is the resident insomniac, and dolphins are never supposed to take naps, which is what I've always said. If I take a nap, I just feel like I'll never sleep again. And he says so many times, he's like, “Dolphins do not take naps, not allowed to take naps.” I love that.

As far as suggestions for how to fix it. I actually don't really have a suggestion. My biggest suggestion would be when you have that earlier meal, are you having a huge meal? Are you normally having a huge meal between 6:30 and 9:30, which you probably are, if you're only eating for three hours every day. So, if you have to eat earlier, you might be able to mitigate that by not having that earlier meal is huge. Different foods might make you feel a certain way. Like for me, like protein makes me feel tired. It's more to digest. If I were to have a lighter meal, like if I were to have a lighter salad early in the day, I probably would not get super tired compared to if I ate my normal meal of pounds of meat, I would probably get tired. Yeah, that was a lot of thoughts. Gin, what are your thoughts?

Gin Stephens: I just had to look back in my email to remember what I was. I'm a lion. Is that what we decided that I was?

Melanie Avalon: You are 100% a lion.

Gin Stephens: Yeah, I'm so much a lion.

Melanie Avalon: You're such a lion.

Gin Stephens: [laughs] Yeah, I'm a lion. I thought that was interesting. That was interesting thought to think that might be related to her chronotype. So, yeah, because it doesn't seem like she's just tired at 6:30 when she eats as if she eats earlier. Fascinating. Yeah, I think you said it all, honestly. As you mentioned, I'm never as alert after opening my window as I was before. But the fact that she doesn't feel it is pronounced when she opens at 6:30 if she does when she opens it earlier, is the part that's interesting.

Melanie Avalon: That's one of the amazing things though that I really love about having an evening meal is, I can use it as that zeitgeber, if I'm saying it right. Basically, it makes me tired every night, even if I would otherwise be a little bit more wired that night. It's a consistent signal, especially if you struggle with insomnia or something like that. Having a consistent eating rhythm is really powerful for regulating your sleep rhythm. So, I can pretty much get my body to shut down every night with my one meal a day. And like I said, being a resident insomniac dolphin, that's really important to me.

Gin Stephens: I also wonder if it has to do with, that she's eating earlier in her fast, and maybe she hasn't fully switched over to-- I don't know, it could have something to do with her blood glucose and ketosis and the fact that she's not as fasted.

Melanie Avalon: It could be a lot of things.

Gin Stephens: Or maybe if she opens earlier, it's a different a thing. If I open earlier, like way earlier than normal, it's usually because there's a special event and I'm eating at a restaurant, and it's something that I don't usually eat and more heavy food. So, that could also be a factor.

Melanie Avalon: I think the biggest question would be before intermittent fasting, if you ate earlier, would you get tired? If you did, then actually nothing has changed. If you didn't, I think it's because food has become a signal for your body to sleep. Yeah, and/or you're eating now a bigger meal earlier, whereas before you weren't because you were eating throughout the day. So, yes. But yeah, if you eat light, that might fix it.

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Shall we go on to our next question?

Gin Stephens: Yes, let's go on.

Melanie Avalon: We have a question from Meghan. The subject is “Question for a friend who is at a healthy weight but has high cholesterol and is prediabetic.” Meghan says, “Hi, I'm Melanie and Gin. Thank you so much for all of the work you put into your podcast. First, I will tell you briefly what brought me here. I gave up wheat last month when I started getting heartburn or reflux every time I had bread or pasta. I then learned about intermittent fasting and started doing that as well. I have quite a bit of weight to lose. I started at 236 pounds, and I want to be around 135. In the past month, I have done clean fast with plain tea and water only. I eat healthy food during my eating window between two to five hours depending on my appetite each day. I have lost 16 pounds so far, yay.

My question today is for a friend. We got together yesterday. She's very slim, but she told me her doctor told her she has very high cholesterol and she is prediabetic. Her A1c is 6.2. Do you know of any journal articles that specifically address the effects of intermittent fasting for someone who is already a healthy weight, but has these health concerns? Since I just started listening to your podcast, I am only on episode 24. I definitely have a way to go to get caught up. Thank you so much for all you do. Megan.”

Gin Stephens: That is a great question. First of all, I want to say, Megan, hooray, I'm so excited for you. You're doing great. You've only been doing intermittent fasting for about a month and you're down 16 pounds. That is a-mazing.

Your friend, if her A1c is 6.2, high cholesterol, prediabetic, you're right, yeah, there's some things she can do to bring down that A1c, work on her overall health. And I do think that intermittent fasting would be a great choice for her. The very best article for anybody who wants to do intermittent fasting for health purposes and not for weight loss, is from the New England Journal of Medicine. The title of it is Effects of Intermittent Fasting on Health, Aging and Disease. And Mark Mattson is one of the authors. It's the one that came out on December 26th of 2019, and really changed a conversation from everyone saying, “Yeah, intermittent fasting for weight loss,” to, “Oh, intermittent fasting for health benefits.” That article really goes through the research and talks about all the things that intermittent fasting can help with. Being prediabetic, that would be one of the things on the list. So, I would recommend that.

You have to register for a New England Journal of Medicine free account to access it, but they're not going to spam you with stuff. You have to put in your email address and register, but it's worth it. You can download the article in PDF form and have a copy to read. So, I would highly recommend anybody who is interested in intermittent fasting for health benefits, if you want to see what all the different health benefits are, they did a great job putting it all together for this article because it's a review article that has all the different publications, all the different things that intermittent fasting can do for you. All in there, categorized, all the research is there. You can go down the rabbit hole of finding all of it. That's what I would do.

Melanie Avalon: I thought that was a great suggestion. A framework to consider about everything, one, is that I think we often assume that you have to be overweight to have health conditions, or maybe more likely, on the flip side, that if you're thin, that you won't have certain health conditions.

Gin Stephens: Can I pop in with a personal story real quick?

Melanie Avalon: Mm-hmm.

Gin Stephens: They often consider Alzheimer's to be type 3 diabetes, high levels of insulin in the brain. Chad's aunt had early-onset Alzheimer's, and she was very, very thin, but she always ate, had Coke and candy bars, and I'm certain her blood sugar was nuts. And she had early-onset Alzheimer's and was thin. She probably could have benefited from some fasting.

Melanie Avalon: I agree. To that point, weight often correlates to health issues, but it doesn't necessarily, and actually, like the Asian population, for example, they tend to be thinner, but they're more prone metabolically to having issues with things like diabetes and blood sugar regulation. A reasoning for it that can happen is that basically, it has to do with energy toxicity and based on your genes, your fat cells may be predisposed to either when they become full, split in half and create a new fat cell. Basically, it becomes really easy to gain weight, because you keep creating new fat cells, and then you keep getting bigger and bigger. While that looks like a problem because you're gaining weight, it's actually protecting you because those fat cells are creating a bank for all of that excess energy coming in. It pushes off until a little bit later getting the diabetic issues, compared to people whose fat cells are not accustomed to doing that genetically, so they don't split and form new fat cells.

What happens in that case is people don't gain the weight that you would expect from excess energy consumption. Instead, it creates a buildup of fuel in the bloodstream, because you don't have fat cells to take in that excess energy, and so stuff is just building up in the bloodstream. The blood sugar is taking too long in the bloodstream, creating diabetes, glycating your red blood cells, which is what your A1C is looking at. Ironically, you can be very slim and actually more predisposed to having blood sugar regulation issues. Yeah, that's something to consider.

I'm also going to link in the show notes to a study called Clinical Management of Intermittent Fasting in Patients with Diabetes. It basically just talks about how intermittent fasting is a viable method for people to manage diabetes, and that's not dependent on them being overweight to start. One of the things to consider is that even if the studies are in overweight patients, I know people can make the argument that if there's a study on overweight patients with intermittent fasting, and they see health benefits, people will make the argument that, “Oh, the health benefits were just because they lost weight, not from the fasting specifically.” I think there's enough literature, like the one that Gin just mentioned, but just in general, in patients who are not overweight seeing health benefits. So, I would not be concerned about that you have to be overweight to experience the health benefits of intermittent fasting.

This could be something great for your friend, I think, especially since, yes, prediabetic, A1c 6.2 and very high cholesterol, this could be something to definitely, definitely try. I will just make a note about the cholesterol is that when people-- Well, you know what? This is something I actually wonder. Gin, I’d be curious about your thoughts on this. A lot of people who are overweight and do intermittent fasting often see a transient increase in cholesterol due to the weight loss, but if it's a situation where she doesn't actually need to lose weight from the intermittent fasting, I wonder if there's a potential of seeing that boost in cholesterol or if it might just address it from the beginning. Does that make sense?

Gin Stephens: It does. Even though someone doesn't “need" to lose weight, they still might lose some. When Chad started intermittent fasting for the health benefits, he did lose some weight. He did not need to, but he got slimmer than he already was. And then he stopped, he didn't just keep losing weight until he wasted away to nothingness. [laughs] He lost some weight and then stabilized at a weight that was lower than he had been but he's still healthy, so he lost some fat.

Melanie Avalon: That's a great point. My initial response was she might see a boost in cholesterol, but I feel that happens the-- I don't know, but I feel that happens to most when people lose a lot of weight in the beginning.

Gin Stephens: Well, yeah, because as you're losing the fat, it ends up in your bloodstream, and so that shows up on your cholesterol test. That's why it's transient as part of the weight loss process. But it's hard to know. Just depends on what your body is doing. It wouldn't be only happening in people who were overweight. It could be someone who doesn't need to lose weight, but they're also releasing some fat.

Melanie Avalon: Exactly. Great question. We will put links like I said to everything in the show notes at ifpodcast.com/episode233. Yeah, I don't think we have time for any more questions. If you'd like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. You can also follow us on Instagram. I'm @melanieavalon, Gin is @ginstephens. A plug again to send us questions for Robb Wolf. Oh, and I just have to keep plugging, listeners, if you'd like to get my new Serrapeptase supplement, you can get on my email list for that at melanieavalon.com/serrapeptase. Yeah, I think that is all of the things. Anything else, Gin, from you before we go?

Gin Stephens: No, I think that's it. I can't wait to hear about your second muffin experience to see if it's just as delicious, the second. I'm still laughing at that, that you love the muffin.

Melanie Avalon: I'm both dreading and dreaming about it.

Gin Stephens: I shared it with the moderators that also have gone through so, I'm like, “Oh my God, Melanie loved them off.” And they're like, “What?” [laughs]

Melanie Avalon: The most amazing thing. Another reason, I think it's going to be perfect to do it this week, is I have to get a colonoscopy this week. It's like a built-in just clean out the system after the muffin craziness.

Gin Stephens: Keep us posted.

Melanie Avalon: I will. All right, well, I will talk to you next week.

Gin Stephens: All right. Bye-bye.

Melanie Avalon: Bye.

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember that everything discussed on the show is not medical advice. We're not doctors. You can also check out our other podcasts, Intermittent Fasting Stories, and the Melanie Avalon Biohacking Podcast. Theme music was composed by Leland Cox. See you next week.

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Gin: GinStephens.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

May 02

Episode 211: Vitamin D, Insulin & Fat Storage, Blood Fat Clearance, Better Sleep, IF Dreams, Bathroom Urgency, And More!

Intermittent Fasting

Welcome to Episode 211 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Gin Stephens, author of Delay, Don't Deny: Living An Intermittent Fasting Lifestyle

Today's episode of The Intermittent Fasting Podcast is brought to you by:

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To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At MelanieAvalon.com/beautycounter, And Something Magical Might Happen After Your First Order!

Five Health & Wellness Trends In 2021 - Vitamin D

Get Up To $200 Off With The Code MelanieAvalon At MelanieAvalon.Com/Sunlighten

100th Anniversary of the Discovery of Insulin Perspective: Insulin and Adipose Tissue Fatty Acid Metabolism

Listener Feedback: Leah - Gin’s New Social Network

Delay, Don't Deny Social Network

IF Biohackers: Intermittent Fasting + Real Foods + Life

Clean Beauty And Safe Skincare With Melanie Avalon 

Lumen Lovers: Biohack Your Carb And Fat Burning (With Melanie Avalon)

Listener Feedback: Alicia - IF And Dreams

Listener Feedback: Britt - ADF Or OMAD? Or Both?

JOOVV: For A Limited Time Go To joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

The Science Of Fat Cells: Losing Weight, Gaining Weight, Killing Fat Cells, Liposuction, Body Contouring, CoolSculpting®, ECM Remodeling, And More!

Listener Feedback: Carolina - Toilet Urgency When Breaking Fast

TRANSCRIPT

Melanie Avalon: Welcome to Episode 211 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Gin Stephens, author of Delay, Don't Deny: Living an Intermittent Fasting Lifestyle. For more on us, check out ifpodcast.com, melanieavalon.com, and ginstephens.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment. So, pour yourself a cup of black coffee, a mug of tea or even a glass of wine, if it's that time, and get ready for The Intermittent Fasting Podcast.

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One more thing before we jump in. Are you concerned about aging? Well, thankfully, fasting is super incredible for its antiaging benefits. It activates genes in your body called sirtuins, which repair your body and help extend lifespan. Also, during the fast, your body can clean up a lot of harmful chemicals which may be taxing your detoxification systems. In fact, the reason people go gray is because their detox systems start producing a lot of hydrogen peroxide when dealing with toxins. Do you know where a lot of those chemicals come from? Your skincare and makeup. As it turns out, there are thousands of compounds found in conventional skincare and makeup that Europe has banned due to their toxic nature and the US has banned less than 10. When you put these on your skin every single day through your skincare makeup, you're adding to your body's burden and likely aging your skin faster.

Thankfully, you can easily clean up your skincare with a company called Beautycounter. They make incredible products that are extensively tested to be safe for your skin. You can feel good about every single ingredient that you put on. They also have an amazing antiaging line called Countertime. Friends, this is a game-changer. It's full of active ingredients which nourish and support your skin, reduce fine lines and wrinkles, and support a beautiful glow. It also has a safe alternative to retinol. So you can get all of the anti-aging benefits of retinol without any of the toxic effects of retinol, because, yes, that stuff is toxic. Guys, put it away now.

You can shop with us at melanieavalon.com/beautycounter. If you use that link, something really special and magical might happen after you place your first order. Also definitely get on my clean beauty email list that's at melanieavalon.com/cleanbeauty. I give away so many free things on that list. So definitely check it out.

Lastly, if you anticipate making safe skincare a part of your future, just like Gin and I do? Definitely become a Band of Beauty member. It's sort of like the Amazon Prime for safe skincare. You get 10% back on all of your purchases, free shipping on qualifying orders, and a welcome gift, that costs way more than the price of the membership. It's completely worth it. Friends, are you fast and clean inside and out? You can with Beautycounter. Again, that link is melanieavalon.com/beautycounter. And we'll put all this information in the show notes. All right, now back to the show.

Hi, everybody and welcome. This is episode number 211 of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Gin Stephens.

Gin Stephens: Hi, everybody.

Melanie Avalon: How are you today, Gin?

Gin Stephens: Well, I'm still at the beach, so that lets you know I'm good. I'm going home tomorrow. I've just enjoyed this week so very much. I was going to go home on Saturday. It is now Sunday, and I'm not going home till Monday. Chad was so sad. I was like, “Oh,” because my sister decided to come down, and then I need just a little more time. I was like, “I'll be home Monday.” He's like, “What? You were coming home on Saturday,” but anyway.

Melanie Avalon: So relaxing.

Gin Stephens: It is. Yeah, I've been doing a lot of work. I had things I needed to do here at the beach property, but, well, I'm recording a podcast. I just recorded an ad for something else. I'm working. To me, this is relaxing. It's my kind of relaxing. [chuckles]

Melanie Avalon: Getting your vitamin D levels?

Gin Stephens: Yeah, I am getting my vitamin D. That is true.

Melanie Avalon: Did I tell you I got my vitamin D tested, and I way overshot everything?

Gin Stephens: Like it's high?

Melanie Avalon: Yes.

Gin Stephens: Well, I don't know that you can have too much vitamin D.

Melanie Avalon: I've been researching it. I don't think so. I don't want to make that blanket statement. Basically, there's only been as far as toxicity studies with vitamin D, there's been, I think, like two, and they were massive, major doses, like things that people would not be doing, but I am going to hold off. I feel like all my vitamin D levels-- because I was 30, which is low and now I'm like 130. Have you had yours tested?

Gin Stephens: Not for a long time. The last time I had mine tested, it was low, but I had not been supplementing, and it was like I'd not been in the sun, because it was wintery.

Melanie Avalon: Yeah, I guess I'll err on the side of having more rather than less. It's so important, the vitamin D.

Gin Stephens: Well, I think so for immunity, I just watched a video, it was a doctor talking about immunity, and he said seasonal cold and flu season-- not to mention coronavirus obviously, but seasonal cold and flu season is very much seasonal low vitamin D season. So, just keeping our vitamin D up is really one of the best things we can do for immunity of all types.

Melanie Avalon: Yeah, I'll actually put a link in the show notes, and I talked about this before on the show, but I did a guest blog post on Sunlighten’s blog, and I did a section on vitamin D with a lot of the studies on COVID, and things like that. It's a very intense correlation.

Gin Stephens: Now I couldn't find, does Sunlighten sauna increase your vitamin D?

Melanie Avalon: No, sorry. I'm glad you said that to clarify.

Gin Stephens: I looked for that and couldn't find anything that indicated that. If it does, that's really exciting, [laughs] but I thought the answer was no, because I looked it up.

Melanie Avalon: They asked that about Sunlighten infrared, and they asked that about like red light Joovv devices. No, those do not create vitamin D.

Gin Stephens: I got excited for a minute, because I was like, “Well, I could be wrong. Maybe I missed it.”

Melanie Avalon: No, they have a health and wellness blog. We have a link for them for our show. I think so.

Gin Stephens: Well. If not, we need one. I love my Sunlighten sauna.

Melanie Avalon: Yes, so for listeners, you can go to ifpodcast.com/sunlighten, and the coupon code, IFPODCAST, gets you whatever their deal is for us. I think it's like $200 off on sauna and free shipping, which is insane.

Gin Stephens: I'm so glad I invested in that sauna. I love it.

Melanie Avalon: It's so great.

Gin Stephens: Yeah, I got the three person that you can get in, and it is-- I wouldn't get in there with two other people. [laughs]

Melanie Avalon: I actually, because I have the solo unit, the one that you lay down in for the first time, because the place where I'm doing my almost daily cryotherapy, they have an infrared sauna. They actually have a Clearlight, which I like that brand too. I realized I hadn't sat in one of those.

Gin Stephens: Really?

Melanie Avalon: Mm-hmm. It's a different experience, being in the cabin unit.

Gin Stephens: Yeah. It's nice and it has a tablet in there, so I can watch TV while I'm using it. You may not want to do that, but I can. I have it on like Discovery+, because I'm watching Discovery+ right now. I'll go in there, and put on an episode or something, and set the timer, and just watch one episode, and then get on out. That's been my new morning routine, at home, not at the beach, because I don't have one at the beach, but get in the sauna, first thing in the morning, use it, then go get in the shower.

Melanie Avalon: It's so funny how we do it opposite. It's the last thing I do. I brought my phone though, into the Clearlight one, and then I was like, “Oh, I think I'm killing my phone.” [giggles] It got really hot. I felt like I was on the struggle bus when I got out the phone.

Gin Stephens: You really aren't supposed to heat those phones up, that's true. For me, now that I'm no longer on Facebook, I used to feel the stress of being in there because I'm like, “What's happening? I'm 45 minutes in the sauna, and I don't know what people were doing in the groups,” but now I'm just like, “I didn't take my phone in. I just got in.” It was so nice.

Melanie Avalon: For listeners, when you have the solo unit that I have, it's hard to describe, but it's like-- I don't want to say a coffin, but you lay down--

Gin Stephens: Like a big sleeping bag?

Melanie Avalon: Yes, that's a good example. A big one so it's not touching you and your head is actually out of it. I have a whole setup. I got this arm to hold a phone, so I can hold the phone over me, and I can read while I'm in it. It's relaxing and productive, and [sighs] one of my favorite things. Guess who I interviewed yesterday?

Gin Stephens: Well, I don't know.

Melanie Avalon: Marty Kendall.

Gin Stephens: Oh, I love Marty Kendall. Yay. Isn't he awesome?

Melanie Avalon: He's amazing, and he was going on and on. He'll probably listen to this. [laughs] It was really wonderful, because I really respect him, and I have for a long time, and he really respects us, and he has for a long time. It's this really cool, mutual respect thing. We were bonding over the fact that neither he nor I, we're not doctors or nutritionists. He's an engineer. I'm an actor, podcaster author, I don't even know.

Gin Stephens: You're a biohacker.

Melanie Avalon: A biohacker. [laughs] Is that my identity label? I guess so. Yes, but, oh, my goodness. Listeners, I can't wait till I air this episode, because it's going to be the resource episode that I refer listeners to now for the misconceptions surrounding keto and insulin and ketones and all of that. We talked for two hours, and we just dived in so deep, but I think it's going to be so valuable just to refer listeners to it.

Gin Stephens: He is brilliant.

Melanie Avalon: Yeah, he's amazing.

Gin Stephens: What I love about him is that he started off thinking certain things, the conventional keto wisdom that we've all read hundred times, but then he realized over time, wait a minute, no, and then he did the work, and has done the actual trials, and he worked with people who are-- I don't mean trials like clinical trials, but they've tried it out, seen what happened, measured things.

Melanie Avalon: I'm trying to remember. I asked him at the end like, “What was the thing that he most changed his mind about?” I try to remember exactly, because we talked about all of this for two hours, so it's all running together.

Gin Stephens: Was it eating a lot of fat?

Melanie Avalon: It was either eating a lot of fat is the key, or it was like that keeping insulin low is the thing, something involving all of that. The idea of constant low insulin or--

Gin Stephens: Right, because we do want insulin to be low during the fast when we're fasting, but the body is so much more complicated.

Melanie Avalon: One of the things we talked about that I think most people do not realize, and even I'm prepping right now to interview Gary Taubes for the case for keto, and I was asking Marty. I've been asking every single authority figure or researcher in this area. What should I ask Gary? I was asking Marty, what would he ask Gary, and one of the things was the difference between basal and bolus insulin, because so many people think that we just release insulin with food and that it's on or off, but the majority of our insulin, I think 80% or something, well, it depends on what diet you're following, but the majority is the insulin, that's just always there.

Gin Stephens: He said that's interesting that he said 80%, I remember a Butter Bob blog post and video, he said, “50%.” I don’t know.

Melanie Avalon: It ranges--

Gin Stephens: Yeah, Butter Bob said 50% of your insulin that you've got circulating is just your natural--

Melanie Avalon: Yeah, and it ranges majorly, since it's a percent, not a specific number. While the specific number of the insulin while fasting might not change, the amount of insulin released when eating might change, depending on the macronutrients. The percentage would change based on your macros, but even though that percentage changes, that doesn't necessarily mean it's changing the amount of insulin necessarily during the fast, while the percentage would change. That was complicated. Did listeners follow that? [giggles]

Gin Stephens: Well, I get that, because the math, as numbers change, percentages change. The range is different, the range changes.

Melanie Avalon: The number might just change for the food based on your macros, but not so much for the fast. One number would change, it could drastically change the percent, but not drastically changed the amount of insulin that you have outside of eating,

Gin Stephens: Those are all ballpark numbers anyway, 50%, 80%. Those are not going to be set in stone for any anyone person, because we're all so different.

Melanie Avalon: 100%. That's what he was saying about the case for keto was that, and I need to revisit it with this lens, but I think the majority of what he talks about is he really just looks at the insulin in response to food. Well, no, because he talks about the baseline insulin state of given individual and smelling foods, I don't know, there's so much. Listeners, I will put this in the study. I found-- I didn't find it. James Clement, who I've had on the show, sent it to me. This amazing new study came out, it's a review. It came out March 26th, so pretty recently, and it's called 100th Anniversary of the Discovery of Insulin Perspective: Insulin and Adipose Tissue Fatty Acid Metabolism. Oh, my goodness, it's blowing my mind. I'm going to have to read it 20 times. It dives really deep into the role of insulin and fat storage and fat release, and there's some really great quotes in there, basically saying with eating fat, specifically, insulin is not necessarily the primary or only factor involving fat storage, and all of these other things can create fat storage as well, and it lists examples of meal fat content, meal timing.

Gin Stephens: We knew that. We knew that already. Or, you and I knew that because- [laughs] but the misconception out there is I don't know why, why it makes no sense that your body can't store fat from fat you eat. I've seen people say that.

Melanie Avalon: It says for example, “Thus, factors other than insulin play more important roles to stimulate adipose tissue uptake,” so that means our bodies taking up fat and “storage of meal fatty acids, including meal fat content, [laughs] rate of meal fat appearance and circulation, repeated meal intake, lower body fat distribution, sex hormones, and other postprandial hormonal responses.”

Gin Stephens: Yep. Really, I think people get it mixed up. Insulin is antilipolytic, I love that word, meaning that, if you have really high levels of insulin, it's hard to be in a really good fat burning state with really high levels of insulin. But that doesn't mean that with low levels of insulin, you cannot store fat. That's the thing that people get mixed up, “Oh, high levels of insulin can't burn fat, low levels of insulin must mean I can't store fat.” No.

Melanie Avalon: 100%, and also with the storing fat, people think, “Oh, fat doesn't release insulin that much, so that must mean it can't be stored,” but the reason it doesn't release that much insulin is because it is easily stored. It's literally the opposite.

Gin Stephens: I was talking on a podcast for Intermittent Fasting Stories. I was interviewing Joel and Renee, a mother-son team of intermittent fasters, they both do intermittent fasting. It was a great episode. We were talking about, “What I would do if I needed to lose weight?” and I said, “I would eat less fat,” because I know how my body is. This was a long time ago before I even knew I cleared fat slowly, but I just knew based on my response results for keto, that my body didn't do well with a lot of fat. I said in that interview, “I would just put less butter on my bread, I would not use as much butter in my cooking, I would lower my fat.” Somebody actually wrote to me and said, “You're wrong. Fat is not the enemy. You cannot store fat,” and I’m like “What?” It just shows me that people are really confused.

Melanie Avalon: Yesterday on Instagram, I'm really trying to get-- I don't know how to say his last name Max Lugavere, the Genius Foods guy. [laughs] He wrote a book called Genius Foods, which is amazing, and then a new book called The Genius Life. I really want to bring him on the show, and people have been asking, and I've been emailing his assistant, but he's not responding. I've been trying to comment on his Instagram stuff to get his attention, but he posted something the other day that was all of these misconceptions about diet, I'm just looking at it right now. It's like eggs are unhealthy, meat is unhealthy, avoid salt, sugar is fine. And then, the next one is fat makes you fat, and then use refined cooking oils and all these different things. I commented and I said, the only one that I think about a lot is the fat makes you fat, because when you're storing fat, probably the majority of it was from fat, not carbs or protein. It's like did the carbs make you fat, or did carbs create an environment that allowed the fat to make you fat?

Gin Stephens: That's a good way of putting it. Had you eaten nothing but fat? For me, yes, you can still store fat. Even Dr. Fung has a blog post about this, where a lot of people didn't want to read it. You know how you put your hands in your ears, you go la, la, [laughs] when you don't want to hear something? He wrote a blog post a long time ago that said, “Who should have bulletproof coffee and fat bombs,” and he was like, “If you're trying to lose fat, not you.” People didn't really read that one or want to hear it.

Melanie Avalon: So many people do say that fat doesn't make you fat, but I feel in most of the cases, it is the fat that's becoming fat. The hormonal environment is determining whether or not it is, so or to what extent it is.

Gin Stephens: I'll never know what happens if you eat nothing but 100% fats, I don't want to do that. It makes me feel yucky. [laughs] It might be hard to overeat fat to that degree, because you're just like, “Gross, I'm done,” but I don't know.

Melanie Avalon: Yeah. If you just ate-- Now, I'm thinking of tangents. If you just ate the C8 MCT oil, I don't think you would get fat. I don't think they would get stored.

Gin Stephens: I think it would make me really sick.

Melanie Avalon: Oh, yes, it would make [laughs] if that’s all you ate.

Gin Stephens: [laughs] Fine. Honestly, I don't know that I'd be able to eat enough of it to get it down, if I could choke it down enough to know if it would make me gain fat, because I wouldn't be able to consume it in that level. That's the thing. It wouldn't be enjoyable. Eww, ugh. [laughs] Anyway, it's interesting question.

Melanie Avalon: Also, oh, wait, one really last thing. I interviewed Dr. Gundry, recently, for his book. It's The Energy Paradox, because he's always got to use the word ‘paradox.’ [laughs] What he talks about a lot is mono diets in his book.

Gin Stephens: Does he like mono diets?

Melanie Avalon: I got so excited. For the longest time, I have thought if you do a mono diet, if something, so just protein or just carbs or just fat, which not so much the fat one, but it makes it very hard to gain weight in such a situation. He talks about the benefits of temporary mono diets basically because they allow the system to clear out, because there's not all these competing fuels. Though his book is about healing your mitochondria, it's a really good book. I learned so much about the mitochondria. It made me so happy, because I was like, “This is what I think about a lot.” He actually advocates intermittent fasting, opening your window with a monotype diet, and then having your second meal later be not a mono diet. I'll put a link in the show notes to his book, and any of the interviews I have done when this comes out, I don't think any of them will have aired though.

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Melanie Avalon: Shall we jump into everything for today?

Gin Stephens: Yes, let's get started.

Melanie Avalon: All right, so to start things off, we just have some very brief listener feedback supportive listener feedback from Leah. The subject is “Gin's New Social Network.” Leah says, “Gin,” and then she says in parentheses “and Melanie”. “I just wanted to tell you thank you so much for starting your own social platform. I got off Facebook this year, and I am so excited to reconnect on your platform. Also, I want to tell you both that I am so inspired by what you have created. I have plans to start a podcast, and create content in the future, and you're both such an inspiration to me. Thanks, Leah.”

Gin Stephens: Well, thank you, Leah. It's dddsocialnetwork.com, for Delay, Don't Deny, that's what the Ds are. dddsocialnetwork.com, and I'm really enjoying it. Like I mentioned before, my life is so much calmer now, because not having to manage half a million Facebook members, [laughs] and the posting. I'm going on in the morning to the DDD Social Network, and I'm going in the evening, a couple times a day, and also, I'm checking my emails, because I get instant emails, if someone posts in the 28-Day FAST Start group or the Ask Gin group. I'm responding to those throughout the day, but it's so much less stressful, so much less pressure. For new intermittent fasters, Melanie, I'm having so much fun coaching them in the 28-Day FAST Start group. People are like, “I'm on day 10,” and they're talking about it. It's exciting to see so many brand-new people joining. It's not just for brand-new people, we have lots of experienced fasters too, but I like to see we're starting fresh with new fasters. Also, just like Leah said, a lot of people who had left Facebook, but missed the support. The long-term fasters who were not on Facebook, but missed the community, so now they can have the community again. It really is exciting.

Melanie Avalon: I'll set up an email that I use just with that group, and then I can set it up to have alerts just for my little group in it, because I went in there the other day, and I was like, “Oh, there's all this stuff.” Like, if there's a group for me in there, I didn't even realize-- Oh, I did realize.

Gin Stephens: Yeah, but you hadn't really poked around.

Melanie Avalon: Yeah.

Gin Stephens: It's so different than Facebook. This is the thing that confuses some people, because they think it's going to be Facebook 2.0 or something, and it's not, because we're used to Facebook serving up the content to us-- I've been on Facebook, or I was on Facebook since 2008 or something, and Facebook decided what you would see, and it showed it to you, and served it up, and you became a consumer of the information Facebook wanted you to see. Versus here on the DDD Social Network--

Melanie Avalon: You're creating the content.

Gin Stephens: Yeah, and you decide where you want to go, and what you want to engage with. You want to see the Melanie Avalon Biohacker Podcast group, you go to it. Some people are like, “Wait, I just wanted to show it to my eyeballs.” We're like, “No, that's not how it works. You’ve got to go there.’”

Melanie Avalon: If I did that, if I create an email, could I get alerts just for--

Gin Stephens: Yeah, you change it to instant on the settings for each group. I don't have every group I'm in set to instant. Just the ones I never want to miss something in. I never want to miss anything in Ask Gin, and I never want to miss anything in the 28-Day FAST Start. But I don't really care what they're doing in the Melanie Avalon Biohacking group, so I do not get instant notifications there. [laughs] Then, they go to your email, and then it's very easy. You just go to your email and go click, and then it takes you right to it. From that click, it takes you right to that post, and then you can respond to it. It's so easy.

The notifications are different than Facebook notifications, but they're way-- and there's more of them, because it doesn't group them together. You know how in Facebook it groups them together? If 20 people commented, it would group them together as one notification, here you get 20 notifications, but it just takes you to the post when you click on it, but they're less buggy.

Melanie Avalon: Okay. Perfect. For listeners, we'll put a link to that in the show notes, and then I always just want to clarify, I still have my Facebook groups. Those are still the place for all of my content. Those are IF Biohackers, Clean Beauty and Safe Skincare, and then I have a Lumen group, but you can just search Melanie Avalon in Facebook.

Gin Stephens: Yeah, and I also still have the big Delay, Don't Deny: Intermittent Fasting support group. I'm just not there. The moderators are running it, and you can ask questions on Ask a Moderator. Today, we got, “Does alcohol break a fast?” [laughs] The answer is yes. But the moderators are handling those questions. It's just the basic questions. If you need more support and you want me to walk you through the 28 Day Fast Start, you need to be at the DDD Social Network.

Melanie Avalon: Perfect.

Gin Stephens: All right, well, we have something from Alicia in Phoenix, and the subject is “IF and Dreams.” She says, “Hello, and happy day to you both. Intermittent fasting is fairly new to my lifestyle. Clean fasting for only six weeks after reading Gin's book, Fast. Feast. Repeat. Since finding your podcast, I've been learning tons. So, thank you so much for your continued efforts in bringing all the new and emerging research on the subject. My question is about dreams returning after little to no dreaming for years. Have you heard about this or think it's connected? If so, how? It was a rare occurrence for me to have a dream, now they're nightly. Since starting IF, I've been experiencing better sleep. I'm feeling more rested, and notice I wake less often at night. I'm super happy about this delightful side effect and would appreciate any thoughts you might have as to the mechanism of how this is happening. Maybe hormone balancing, deeper REM sleep?

Side note, here's a little info about myself and my eating window/pattern. I'm 5’5” and weigh 126 pounds. I started eating intuitively in 2019 after starting a daily yoga routine. Whole foods, lots of plants, cutting out what made my body unhappy, i.e., processed and sugar foods. I was inadvertently doing IF, but not clean, waiting to eat until after my noon yoga session. I lost the 30 pounds I needed to within a nine-month period, but a couple creeped back on when I started loosening my strict no-sweets policy.

Oh, a little tangent here. It made me laugh when I heard, Gin talk about her love for black bean brownies on a recent episode. They are my favs.” Yep, me too, Alicia. They're so good. People think they sound weird if they haven't ever had them. That's just a little side note there. [chuckles] 

Melanie Avalon: What's funny is, it doesn't even remotely strike me as weird. I'm like, “Oh yeah.”

Gin Stephens: It's so good. [laughs] All right, Alicia says, “Black bean variety are the best, and I've tried many, many types of alternative whole food brownies. Anyhoo, those couple pounds fell off after adopting the IF lifestyle. It was fairly easy at first, except the black coffee since my DNA report shows, I'm more likely to detect bitter taste like Gin, but I've grown to like it. Clean fasting ever since. My fasts last from 19 to 23 hours, although my average is 21, i.e., until I feel good, always some veggies, and usually something sweet to close my window. When I'm being good, it's dates, yum. When I'm splurging, it could be ice cream or a cannoli. Not often do I get those, probably for the best. Never feeling guilty. Thanks in advance. Lots of love to you ladies, Alicia. Oh, and I also have an Oura ring and love it.”

Melanie Avalon: Oh, I missed that. I didn't see that part.

Gin Stephens: Oh, by the way, I had ice cream yesterday, and it was amazing. [laughs] I'm at the beach with my sister, ice cream was on the menu. We did a lot of walking, we were shopping, and then we went and walked around a place called Brookgreen Gardens, which is just beautiful. It's spring and they have all these gardens, it's a place to see. Oh, I saw an owl. A baby owl.

Melanie Avalon: Oh, you saw baby owl?

Gin Stephens: There's a baby owl, and they had something called Live Oak Alley. The baby owl was up in the tree, and all these people were taking pictures of it, like professional photos, and it was just so fluffy and cute, and it was big, anyway.

Melanie Avalon: Oh, how big is a baby owl?

Gin Stephens: It's whatever, a big kind of owl is. It's a big species of owl. I can't remember the species that it is. Whatever they have down here in South Carolina that are really big, it's that. The baby is as big as the adult of some species of owls. It was so cute up in that tree. Anyway, tangent, sorry.

Melanie Avalon: It's appropriate, because owls and dreams at night.

Gin Stephens: Well, that's true. My point was I ate the ice cream, then I walked a lot. I didn't have restless legs, I didn't have any ill effects. I slept great. That was the good news.

Melanie Avalon: Well, I really, really love this question. I'm so happy for you. It sounds like she's really found the diet and lifestyle that works for her, which is awesome. She has her Oura ring, which is awesome. For your question, I actually asked Dr. Kirk Parsley, who is a sleep expert who I've had on the Melanie Avalon Biohacking Podcast multiple times. I sent him your question. Here is his answer.

“Her sleep is almost certainly improved by improving insulin sensitivity and tighter glucose control, increased dreaming and more memories of dreams as a second order consequence of better sleep, and epiphenomenon.” I asked do people dream even when they don't remember it, he said, “Yes, remembering dreams depends a lot on waking and temporal proximity to the dream. Basically, it's most likely that your sleep is getting better, because of all of the health changes with your insulin regulation that you've experienced with intermittent fasting, and then it sounds like we do always dream, but whether or not remember it has to do with the timing of when we wake up.” That's a short answer, but do you have thoughts, Gin?

Gin Stephens: No, that's what I was going to say as well. We do always dream, whether you remember it or not, and that people don't know that because if you don't remember it, you're not aware you dreamed, but you did.

Melanie Avalon: Yeah. You can still have increased dreaming and more memories of them, because you're getting better sleep. Shall we go on to our next question?

Gin Stephens: Yes.

Melanie Avalon: All right, this question comes from Britt and the subject is “ADF, or one meal a day, or both.” Britt says, “Hi, ladies. Love your podcasts and books. I'm a postmenopausal 53-year-old, and currently weigh around 190 pounds. I lost weight in 2010. I was 256 pounds, and she went to 132 pounds after a gastric sleeve, and I kept it off mostly until about two years ago by focusing on protein and veggies and incorporating fasting after discovering Dr. Fung. Between COVID and a foot injury, I regained a considerable amount of weight last year, so I'm starting this back on track with fasting. I have no trouble fasting on a daily basis 16 to 24 hours. It didn't seem like I was losing consistently, but I don't have the data to look back at. Now, I've got 60 plus pounds to re-lose.

After hearing Megan Ramos mention that 36 to 42 hours often works better for women, I decided to give it a try. I find it a lot harder to go the full 36 to 42 hours. Not physically, I don't have much hunger until the very end, but it's been fairly difficult mentally. I've struggled with feelings of deprivation and find myself thinking about eating at the end of the first day probably, two out of every three fasting cycles. I'm wondering what advice you might have. Is it really worth pushing myself to do the three longer cycles per week? Is there that much of a difference in weight loss? Do I kick off the year with ADF, and go for maximum weight loss? Start every fast with something like a 20-hour goal, and keep going if my head is in the right place that day? Just do a longer fast one day a week, and work my way back up to three, or kick back to one meal a day and save ADF for a future stall?” Those are a lot of options. She thought this through. She says, “Insight appreciated.”

Gin Stephens: All right, so there's a lot to unpack in there. First of all, I want to say, this is my experience, me. I lost 75 of my 80-ish pounds-- since I don't know what I weigh exactly, we'll say 80-ish. I lost the first 75 with a daily eating window, not doing any ADF or longer fasts during that period of time. I didn't do really ADF. I'd done it way before in earlier tries with fasting back in that 2009 to 2014 struggle period. When I wasn't consistent with anything, I would dabble in eating window, and I would dabble in alternate day fasting and nothing really stuck, so I wasn't consistent, but when I did finally get consistent and lose the weight in 2014 to 2015, it was with the daily eating window approach.

When you say, “works better,” well, that worked fine for me. It was after The Obesity Code came out when I was already in maintenance, but struggling with a little bit of weight regain, which I blame on the fact that I was not fasting clean, because I didn't understand all of that until after I read The Obesity Code, and then I switched to the clean fast, lost the weight I had regained, but right after I read The Obesity Code, I did start doing a 4:3 approach, because he doesn't really have a plan in the book, in The Obesity Code except the appendix at the back, he does have like a 4:3 kind of, where you're doing like three-- Like, you said that Megan Ramos mentioned three 36- to 42-hour fast per week, so that's what I did. I'm like, “Well, that's what he says, so I'm going to do it.”

I did it. I did re-lose, it was about eight pounds that I had regained, I did re-lose those doing that approach, and I also had switched to the clean fast. Did I re-lose those eight pounds, because I was doing ADF or, the 4:3 approach or did I lose them because I was finally fast and clean? We'll never know, because I can't go back in time and replicate that study with a different approach. I did struggle with feelings of deprivation like, you're saying, Britt, that you went through.

Do you need to do it to lose weight? Well, clearly not every woman needs to do it to lose weight, because I didn't. Do some women find that it's an approach that really helps their bodies? Yes, 100%. Especially, if you're insulin resistant, you've been overweight and obese for a long time. Now, you're talking about how you lost a great deal of weight in 2010 after a gastric sleeve. You do have a history of obesity and the weight loss surgery. That was a while ago, but you kept it off, and then you regained it, I guess with the stress of COVID and your injury, so you're getting back on track there.

You may need to throw in a longer fast here and there, but it's really not all or nothing. If you've got Fast. Feast. Repeat., I want you to reread the Intermittent Fasting Toolbox section and pay attention to the part in the book where I talk about a hybrid approach. It's really not all or nothing, where you have to either do daily eating window, or do longer fasts. You could throw in one 36-hour fast. Here on the DDD Social Network, our moderator, Roxy leads us through Meal-less Monday. I don't do it. I don't do Meal-less Monday, but a lot of people do. They start off every Monday with one longer fast to 36 to 42 hours, followed by an up day, and then the whole rest of the week, you could do daily eating window approach if you want to. That's just one way you could do it.

Once a week, after a weekend, some people find that just starts the week off right, and it feels good after a weekend where they might have had a little more indulgence than usual. It also keeps you from having that adaptation that you might have, because even though intermittent fasting does protect us metabolically in many ways, you still can adapt if you do exactly the same thing day in day out. Fortunately, for me, I never do, because I'll have a day where I'm just hungry and I eat more, I've never really fallen into that rut of 23:1 day after day after day or something. I just naturally switch things up. If you find yourself naturally not switching things up, then you might need to purposefully do some switching up.

Oh, one other thing that I highlighted that was so important. This sentence right here, “It didn't seem like I was losing consistently, but I don't have the data to look back at.” Okay, I really, really, really do not want you to go by feel or what it seems. I don't want anybody to do that. When I was trying to be an intuitive eater, and they're like, “Just eat intuitively and you'll be fine.” I was not good at knowing what my body was doing. I could gain a whole lot of weight without feeling it. You got to have some data. I want you to reread the Scale-Schmale chapter of Fast. Feast. Repeat., and if you don't want to use the scale, don't use the scale. That is only one way to do it. Use measurements, use progress photos, use honesty pants, but use something. If you are going to use the scale, weigh daily, and you need to calculate your weekly average, or use an app like Happy Scale that does that for you and shows you your trend. I don't want anybody to go by what it feels like. That is the number one worst way to know whether you're losing or gaining. I'm puffy right this minute, because I ate two meals yesterday with ice cream in between. “Feel like I might be gaining weight.” Am I? No. I'm just puffy. You really can't go by how you feel. I don't want you to do. That is not a good tool.

Melanie Avalon: Awesome. I have three thoughts. The first thought was, it's ironic. I don't know if it's ironic. Okay, if I read her question a little bit out of order, and if I just read the end, and she's asking about what to do to lose this stubborn weight, I would suggest without reading the first paragraph of her message exactly what she did the first time around, which would be a high-protein veggie diet with a normal one meal a day type fasting window. It sounds like that's what worked for her the first time. I'm wondering why she doesn't want to do that again. It seems that instead she wants to do these really long fasts, but she doesn't like fasting longer.

Gin Stephens: Well, she doesn't say she did one meal a day at the beginning. She doesn't say that that's what she did. She discovered Dr. Fung, focused on protein and veggies. Maybe she was doing longer fasts, because a lot of people--

Melanie Avalon: And incorporating fasting.

Gin Stephens: Yeah, because we don't know what she did at the beginning. Well, although she does say after hearing Megan Ramos mentioned, “I decided to give it a try.”

Melanie Avalon: I feel this is a new idea to her.

Gin Stephens: Maybe.

Melanie Avalon: She finds it difficult mentally, so it's something that she is struggling with the concept and actually implementing it. For me, when it comes to weight loss, yes, the longer fasts are an avenue to that potentially. I believe the amount of change you can make if you haven't addressed the food choices within just a “normal fasting” one meal a day type window are extraordinary. I would suggest exactly what she already did, which was the protein and veggies. That's what I would suggest, is doing that unless for some reason that you don't want to do that again.

The second question was-- oh, this is a question for you, Gin. Just the concept in general, how do you feel about the concept of starting every fast with a 20-hour goal, and keep going if your head is in the right place that day? Is that something that you ever recommend to people to do?

Gin Stephens: When you start off with a goal that everyday must be 20, then I feel like, you're going to set yourself up for feeling disappointed and you've failed if you don't make that. You could say, “I want my week to have an average of 20,” or something like that, because then you'll have some days where it might have been 22, and another it was 18, but you still had an average of 20. Whereas, if you said every day, I'm going to make it to 20, that day that you did 18, you might feel like you failed, but really your average was 20.

Melanie Avalon: What's ironic is that was what worked best for me.

Gin Stephens: Was what? Every day it had to be 20?

Melanie Avalon: Well, not 20 specifically, but focusing on the minimum fasting hours, that was the most freeing approach for me.

Gin Stephens: Well, that's the thing. You have to find what's the most freeing approach to you, but a lot of people beat themselves up when they set a goal of, “Every day I'm going to do 20, and then I have permission to eat.” That's a rule, that's a diet rule that it might help you, maybe that's the thing that makes you successful, and there are people like that. But there are also a lot of people that feel like, “You've failed if you don't then make it to 20.”

For me, I am more of the average person, like I said. As long as I'm doing the average, this day was 18, but that day was 22, “Hey, it worked out.” That gives me flexibility, but also having a goal, but it's still a flexible goal, but it still averages out to be 20.

Melanie Avalon: How is it different from having an end to your eating window?

Gin Stephens: What do you mean?

Melanie Avalon: The way I like to do fasting is the marker that I have, and we've talked about this a lot before on the show, but the thing I'm counting and the marker that I have is the fast, and then when I eat, there's no rule or boundary on that. Compared to when you flip it, some people put the rule and boundary.

Gin Stephens: See, that was me. I was the eating window person. If I wanted to get a little more structured ever, if I needed to lose weight or something, I would work on focusing the length of my eating window and shutting it down. For me, tracking the eating window is a better approach, because if I have too long of an eating window, I can overeat. For me, the eating window was a better thing to try. As long as I kept it to five hours or less, that was better. My fast might have been 18, but my eating window still was 5, and then maybe the next day my fast was 22, but then my eating window was still kept it to less than 5.

Melanie Avalon: You really have to find what works for you. The only reason I wanted to elaborate on it was I didn't want to discourage, because like I said, for me, that's what works best-- is that I don't do it really anymore, but in the beginning, that's what really, really worked for me with minimum fasting hours, and then no rules, no regulations around the eating. That was just ridiculously freeing for me. Some people do better with the opposite, which is not having really any rules or regulations around the fast, and then having more rules and regulations around the eating window just as far as determining times of things.

Gin Stephens: It's what do you struggle with. For me, it was, “All right, I've had enough now, it's time to stop, my window has been open for five hours.” [laughs] That was like, “Okay, that's enough.”

Melanie Avalon: The question I was trying to get to-- because I think we're focused on the 20 hours, the question I was trying to get to though was, how do you feel about if somebody wants to do one of these longer fasts, the ones that Britt was referring to. The idea of I'll just do my normal time restricted eating intermittent fasting window, and then if I feel like it, go longer, how do you feel about that concept?

Gin Stephens: Well, that plays into the idea of intuitive eating. I like the idea of listening to your body, obviously. If you get to hour 20 and you say, “Am I hungry?” I'm really not. You give yourself permission to eat if you want to, instead of telling yourself you can't, or you're going to fail, and you can also do the down day approach where you have the 500-calorie meal on the down day. You could get to hour 20 and say, “All right, do I want to continue to fast to 36 hours?” Or, “Do I want to just play it by ear?” Or, “Do I want to have a down day meal?” Have a 500-calorie meal, and then close your window, and then the next day is an up day. That's also a perfectly good approach. Anybody who's like, “What is she talking about?” If you haven't read Fast. Feast. Repeat., the chapter on Alternate Daily Fasting Approaches. You can have a full 36- to 42-hour fast, or you can have a 500 calorie down day, where you fast clean, then you have one small 500 calorie meal, and then you start a second fast, and then the next day is your up day.

Melanie Avalon: Perfect. You're always such a wealth of knowledge.

Gin Stephens: That's because I got all this part down pat. [laughs]

Melanie Avalon: Don't ask me about ADF and all of this.

Gin Stephens: There's so many ways you can adjust it. What I really was interested in is feedback after people read Fast. Feast. Repeat., I talk about the hybrid approach, which is really I made that wording up. I didn't make up the word ‘hybrid,’ of course, but I applied it to fasting, I'd never seen it applied there, but people were like, “I had no idea you could mix and match.” I'm like, “Yes, yes, you can.” We're so used to following plans where people tell us exactly what to do, and instead, “No, this is your Intermittent Fasting Toolbox, and you can do whatever you want,” and there's the freedom.

Melanie Avalon: Taylor Swift says, “take my hand, wreck my plans, or something like that from Willow.

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Shall we do one more question?

Gin Stephens: Yes.

Melanie Avalon: Oh, wait, I think it's take my hand, wreck my plans, that's my man.” Okay. I wanted to actually throw out one. It's not really a resource, but I actually did just post a blog post all on fat cells. The reason I'm bringing it up, as I mentioned, because she had gastric surgery, right? Yes. I do talk about that a little bit. I dive deep into fat cells and burning and how they expand and how they shrink, and I address the myth of do fat cells die, because people think that they don't ever die naturally, but they do. They do about 10% per year. And then, I actually talk about different fat removal methods, things like CoolSculpting, liposuction and things like that, and I ponder the implications of that and what that leads to weight regain afterwards. It's interesting to hear for example, well, she a gastric sleeve so that creates weight loss by not actually removing fat cells, but by shrinking your stomach. If listeners are interested, it's at melanieavalon.com/fatcells.

Gin Stephens: All right. We have a question from Carolina, or Carol-eena, either, it's a beautiful name, as I'm sitting here in South Carolina recording. Her topic is “Toilet urgency when breaking fast,” and she says, “Good day to you. I've been doing IF for a year or so with some 24 hour and 36-hour fasts now and then. A very common occurrence for me is to have toilet urgency with number two very soon after breaking fast. Any thoughts, please? Thanks, Carolina,” or Carol-eena.

Melanie Avalon: All right, Carolina. I would say Caro-lina, but who knows. We've had questions about this before, and it can obviously be a lot of things. One of the things that I have read that I feel makes a lot of sense to me that it could be is just when we eat, even though we're putting in food at the top of our system, and it's in the stomach and the small intestine, that tends to stimulate peristalsis, so digestive movement throughout our entire digestive tract. When we eat, it can stimulate our lower colon, our large intestine, and depending on the state of our large intestine in general, which depends a lot on your gut microbiome state, it can basically start that process, and depending on what the environment situation is down there, that might manifest as diarrhea. That's an option. Another option, I don't know what you're eating, but people can experience this effect when they have fat with a meal and it creates stimulation of the gallbladder, and that can lead to an effect down there.

As far as my suggestion about the solution, and we just really don't have enough information to know, but it would be something where you would want to work with your food choices to try to address your gut microbiome state down there. Finding the diet that works for you for that, and I know that's really vague. As far as supplements might help, probiotics can potentially help. I really like P3-OM with BiOptimizers. They're actually the sponsor on today's episode, so you can listen to the ad for that to get a coupon. I actually just emailed them last night and I said, I was like, “Can you send me some more P3-OM?” because I'm running out.

I really think that looking at your food choices would be the thing to do here. The reason I think it starts happening a lot for a lot of people with fasting is you've changed from eating throughout the day and having this peristalsis and slow movement throughout the day, compared to a fasting situation where it's more of a-- sort of like a shock. You haven't been eating and then you do eat, and so it just turns on all of this movement. That's my thoughts, Gin. What are your thoughts?

Gin Stephens: We hear it a lot in the communities that people have this issue. Not a lot of people have it, but we hear it frequently. That's the way of putting it. It's a common thing that we hear that happens to some people. I'm so glad that it didn't happen to me, though. [laughs] This is a problem I'm glad I didn't have. I feel your pain, those of you that have had this issue, because I'm sorry, I know that it's not fun, and you're like, “What's happening?” What Melanie said, trying to get your gut health back in balance is a great idea. Just know that, yeah, it's your body getting things moving again, really.

Melanie Avalon: Yeah.

Gin Stephens: Just the food.

Melanie Avalon: The food choices. That actually made me think of something, Gin.

Gin Stephens: Okay, what?

Melanie Avalon:  I have a question for you.

Gin Stephens: All right.

Melanie Avalon: I've been dying to know, are you still implementing anything that you learned from your Zoe trial?

Gin Stephens: That's a great question. I've got it in the back of my mind. I will never not know that information about myself. It helps me just feel confident in my food choices, but I already was. Knowledge is power. Like I said, it confirmed what I knew about what foods really worked well for me and taught me a few things about that, and so, do I follow it like, this is how I eat exactly according to these recommendations? No.

Melanie Avalon: What dd they recommend for you?

Gin Stephens: It's not as easy as just saying that. There's an app and you can plug things in and see what things work well for your gut, what things work well for you based on your blood clearance, basically you know how quickly you clear blood glucose, how quickly you clear fat. What really was interesting to me, was how the timing of what I eat makes a difference as far as if I eat too much fat in a concentrated period of time.

For example, it would be better for my body to eat over-- maybe eat a little something to open my window, and then wait a while longer-- If I eat something high fat, wait longer before I eat again. The same amount of food in a six-hour window if I'm eating a lot of fat, would allow my body to clear the fat before I put more in.

Melanie Avalon: What's really interesting is, I don't know enough about the details, but it's like that study we mentioned at the beginning where I was saying that fat--

Gin Stephens: Fat clearance. 100%.

Melanie Avalon: Or something about the timing of fat into the bloodstream was a factor. What did it say?

Gin Stephens: I think you use the word ‘fat clearance.’

Melanie Avalon: Uptake and storage of meal fatty acids including meal fat content, rate of meal fat appearance in circulation. All of these factors are so, so important.

Gin Stephens: We've all been trained by the diet industry that the only thing that matters is calories in, calories out. If you're eating the exact same thing, or the macros, the exact same macros, the exact same calories, why does it matter if you eat them over one hour or six hours? But the way your body handles it, it really can matter.

Melanie Avalon: Sorry, I'm just remembering something that I-- I don't know if we have time. Okay, I'll tell it really quick. Dr. Gundry’s book that we talked about, there was a study. Are you familiar with the NIH study? There was one study in monkeys. I don't know the details, but there were two different institutions that did a study in monkeys, and they were looking at calorie restriction. One of the groups testing the monkeys, the monkeys were on a high fat, sugary, processed diet. The other monkeys, they were on a more whole foods type diet. Both of the monkeys had health benefits, but only the monkeys on the processed diet had increased longevity.

Gin Stephens: Processed food diet had better longevity?

Melanie Avalon: Yes. They were trying to theorize why that was, and Dr. Gundry was saying that he had theorized with other people that it was the low protein content of the processed diet that was the reason. Then, they did a follow-up study. I got so happy, because I read this. Then I was like, “I think I know why what it was.” Dr. Gundry doesn't really come out and say this, and I talked with him. When I interviewed him, and I asked him about it, and I was like, “Is it this,” and he said, “Yes, it's that.” He said the publishers made him word it really weird, because he couldn't come out and say this. [laughs]

They did a follow-up study with mice to try to figure out what was going on, and they did all different setups. They did mice that were eating their normal food all throughout the day, and then mice that were eating the food in a calorie restricted and a fasted window, like a time-restricted window, and then mice that could have all of their normal food, but in a time restricted window, and they were trying to figure out what was going on. Long story short, they found that the longer fasting was creating the most health benefits. The theory with the monkeys is that the high fat diet, because they ate for a shorter amount of time, because in order to control the calorie situation, they would give it just at one time, they didn't have access to it all day.

Gin Stephens: They had longer fasting. That was a variable. It wasn't the food, it was the longer fasting.

Melanie Avalon: Right. The monkeys eating the whole foods, it took them longer to eat it, compared to the monkeys that ate the processed foods, they ate it really fast, and then they had a longer fast, and they actually had more health benefits, and this is all theorizing. With calories, if they are eaten and cleared a lot faster, it matters. The timing matters, because I read the section in his book. I kept reading it over and over and over again, because I was thinking what I just said. I was like it just sounds, because the processed food was digested way faster, but they had a longer fast, and that was where the benefits came. He doesn't outright say that, because the publishers didn't want him to make it look like he was saying eat processed food.

Gin Stephens: There's never been a study that had ultra-processed food lead to better health outcomes, with all other variables being equal.

Melanie Avalon: Yeah. With all other variables constant, yeah.

Gin Stephens: See, that's the thing. You can't draw conclusions when the variables are so unequal.

Melanie Avalon: What you'd have to do for that study is you'd have to have ultra-processed food, same amount of calories in whole foods, and then you'd have to dose out the processed food, so that the time window is the same time window as the whole foods.

In any case, this has been absolutely wonderful. A few things for listeners before we go. If you'd like to submit your own questions for the show, you can directly email questions@ifpodcast.com, or you can go to ifpodcast.com, and you can submit questions there. We have all the stuff that we like at ifpodcast.com/stuffwelike. The show notes for today's episode are at ifpodcast.com/episode211. And then lastly, you can follow us on Instagram. I'm MelanieAvalon, Gin is GinStephens, and you can join our various groups that we talked about in the show notes. Anything from you, Gin, before we go?

Gin Stephens: No, that's it.

Melanie Avalon: All right. Well, this was absolutely wonderful, and I will talk to you next week.

Gin Stephens: All right, bye.

Melanie Avalon: Bye.

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember that everything discussed on the show is not medical advice. We're not doctors. You can also check out our other podcasts, Intermittent Fasting Stories, and the Melanie Avalon Biohacking Podcast. Theme music was composed by Leland Cox. See you next week.

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