with GIN STEPHENS and MELANIE AVALON
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Serrapeptase is a proteolytic enzyme created by the Japanese silk worm. When taken in the fasted state, it enters the bloodstream and breaks down unwanted proteins, fibrous tissue buildups, and overgrowths. It can work wonders for clearing mucous and sinuses, breaking down fibroids and adhesions, easing pain and inflammation, and so much more!
DOSING: Start with the recommended dose, and titrate up as desired. If you experience stomach discomfort or negative side effects (uncommon, but known to happen), consider stopping or trying another brand.
ENTERIC COATING: Serrapeptase is easily destroyed by stomach acid, so supplements typically utilize enteric coatings to ensure absorption in the small intestine. Some brands encapsulate the actual serrapeptase compound, while others coat the capsules. There are proponents of both methods, so consider trying different brands to find what works for you!
BRANDS: Here are some of the brands Melanie has personally experimented with, and recommends!
Doctor's Best was the first brand Melanie used, though they’ve recently changed their formulation. It contains the serrapeptase enzyme, calcium (from tricalcium phosphate and calcium stearate in Serrateric™), cellulose, and an enteric coating called Serrateric™ (which the company claims is a "superior alternative to enteric coating that protects the individual enzyme until it reaches the intestine for optimal absorption,” made of maltodextrin, tricalcium phosphate, calcium stearate, microcrystalline cellulose, and medium chain triglycerides), in a delayed release vegetarian capsule made of modified cellulose, gellan gum, and purified water.
Serra-RX contains enteric coated serrapeptase (using a compound called peptizyme SP) in a minimal ingredient capsule made of vegetarian cellulose.
Serra-125K contains serrapepatse and calcium, with microcrystalline cellulose in a delayed release capsule made of hypromelluse, water, and gellan gum.
iSerra contains only serrapeptase in a delayed release capsule made of microcrystalline cellulose, hypromelluse, water, and gellan gum.
In addition to serrapeptase, Enzymedica's SerraGold contains additional proteases, calcium, and magnesium, and is purported to work without an enteric coating, due to being made from (what the company told me) is a "hardy bacterium source called Seratia E15" which "is pH balanced to survive the digestive tract and make the transit to the small intestine where it is absorbed into the blood stream." It is supposed to be easier on the stomach due to the lack of coating, coupled with the mineral blend.