Oct 23

Episode 288: Fiber, Psyllium Husk, Glyphosate, Constipation, Nutrient Timing, Hunger During The Fast, Protein, Bioidentical HRT, And More!

Intermittent Fasting

Welcome to Episode 288 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

BUTCHERBOX: Grass-Fed Beef, Organic Chicken, Heritage Pork, Wild-Caught Seafood: Nutrient-Rich, Raised Sustainably The Way Nature Intended, And Shipped Straight To Your Door! For A Limited Time Go To butcherbox.com/ifpodcast And get one 10-
14 lb Turkey FREE in your first box! 

AVALONX Magnesium 8: Get Melanie’s Broad Spectrum Complex Featuring 8 Forms Of Magnesium, To Support Stress, Muscle Recovery, Cardiovascular Health, GI Motility, Blood Sugar Control, Mood, Sleep, And More! Tested For Purity & Potency. No Toxic Fillers. Glass Bottle.  Get on the email list to stay up to date with all the special offers and news about Melanie's new supplements at Avalonx.Us/emaillist, and use the code melanieavalon for 10% on any order at Avalonx.Us and MDlogichealth.com!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get One 10-14 Lb Turkey FREE In Your First Box!

How She Grew Pre-Sale! 

The Melanie Avalon Biohacking Podcast Episode #165 - Dr. Karen Becker

Go To yummerspets.com And Get 10% Off Sitewide With Code MELANIEAVALON!

Listener Q&A: Becca - Benefiber and psyllium husk pills

Simply Fiber: Digestion Resistant Starch/Fiber Blend

FOOD SENSE GUIDEGet Melanie's App To Tackle Your Food Sensitivities! Food Sense Includes A Searchable Catalogue Of 300+ Foods, Revealing Their Gluten, FODMAP, Lectin, Histamine, Amine, Glutamate, Oxalate, Salicylate, Sulfite, And Thiol Status. Food Sense Also Includes Compound Overviews, Reactions To Look For, Lists Of Foods High And Low In Them, The Ability To Create Your Own Personal Lists, And More!

Listener Q&A: Samantha - Nutrient Timing?

#224 ‒ Dietary protein: amount needed, ideal timing, quality, and more | Don Layman, Ph.D.

Use Code CYNTHIA30 for $30 off or MEL for $50 off at lumen.me!

Listener Q&A: Moose - Struggling with IF

Ep. 206 Pt 1: A Deep Dive into Perimenopause- Hormonal Imbalances and Birth Control with Dr. Tabatha Barber

Ep. 212 Pt. 2: A Deep Dive into Hormonal Imbalances and Menopause with Dr. Tabatha Barber

AVALONX MAGNESIUM 8: Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

Listener Q&A: Robin - Two Questions

The Melanie Avalon Biohacking Podcast Episode #123 - Dr. David Minkoff

Get a discount at melanieavalon.com/perfectamino with the code melanieavalon

Ep. 198 – Dispelling Myths About Hormone Replacement Therapy

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 288 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time and get ready for The Intermittent Fasting Podcast.

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Hi everybody and welcome, this is episode number 288 of The Intermittent Fasting Podcast. I'm Melanie Avalon, I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hey, Melanie, how are you today?

Melanie Avalon: I'm good, how about you?

Cynthia Thurlow: Doing well, just in the throes of homecoming and trying to narrow down options for my grumpy 14-year-old child who is intermittently grumpy but today it's mostly grumpy.

Melanie Avalon: Homecoming like homecoming dance?

Cynthia Thurlow: Yeah, so they have a homecoming event. My kids go to two different high schools and my older son’s already had homecoming, and so this is my younger son's first opportunity to go and today I finally got him to tell me what he wants to wear. And it's an interesting compilation, it's interesting to see between different high schools what kids are wearing and I have my work cut out for me.

Melanie Avalon: Just having flashbacks now. I'm just thinking about how funny growing up there is the key moments where you get to dress up and wear dresses. And now in my life, any chance I can get, I like to dress up for things with dresses.

Cynthia Thurlow: I love it. I'm actually in the midst of finalizing my outfit for this black-tie event for an event I'm going to in Scottsdale. And my poor husband was watching just like box, after box, after box, coming to our home because we live in a--

Melanie Avalon: Did you order from Macy's?

Cynthia Thurlow: I did not, I did not. It was from a variety of places. There is a wonderful woman I work with who's a stylist and I love her to pieces and she knows me really well. And so, we were trying to find a heel that wasn't six-inch stilettos because I was trying to explain it. I was like, I cannot stand in five-inch heels all night long, my feet will hate me. And I finally found the right dress, and I found the right bag, and I found the right shoe, and I found the right earring. And so now I feel I'm finally I can exhale and I have my outfit for next week. Because I don't get an opportunity to get that dressed up all that often but I will be on stage a couple of times, so, I'm excited.

Melanie Avalon: Yes, that's the crème de la crème, the black-tie events. I have one coming up in November and, "Oh, it's so exciting." I'm like all about it.

Cynthia Thurlow: I know you are you wearing black?

Melanie Avalon: Oh, yes. Always.

Cynthia Thurlow: I love it. I'm wearing like a-- it's an off shoulder, it's maroon, it's fitted, which is generally what I look better in any way. And then these really beautiful shoes and beautiful handbag. And because you have to have something to throw your lipstick and your phone into, now we're getting very nuanced, but I love getting dressed up. And it's a full day, I have a documentary I'm participating in, and then I have that in the evening. And I have to give an award out. I will be on stage and have to be 100% and I was laughing and saying I think I'm going to need a nap because I'll be on Pacific Coast time. And my body's going to think it's a lot later than it is?

Melanie Avalon: How tall are you again?

Cynthia Thurlow: 5'3.5”.

Melanie Avalon: Oh, we've talked about this. You look a lot taller.

Cynthia Thurlow: Everyone tells me that. It's one of the most common things people are like you're short, and I was like, with heels on I look very tall. But I usually, I've started now wearing heels on stage. And then my feet have absolutely decided they're done with heels, I almost always bring some fashion sneakers that I have that are awesome, they're very neutral, and then people are like, "Oh my God, you're so petite." I'm like, “Yes, I am.”

Melanie Avalon: That's how we're similar to. People say the same thing about me. They think I am a lot taller.

Cynthia Thurlow: How tall are you?

Melanie Avalon: 5'4.5”.

Cynthia Thurlow: Oh, yeah, so you're not much taller than me?

Melanie Avalon: Yeah, I actually love my height. I would to be like really tall. I don't know I think it could be fun. I like when your average female height, which I think literally 5'4.5 is average female height. I can still wear you're mentioning-- I love wearing really tall heels. I can still wear the really tall ones and then be a really good height.

Cynthia Thurlow: Yeah, well and it's funny. Lewis Howes last week was humored because I came in, in my fashion sneakers, and he complimented me on those. And then I was like, "Oh, hang on a second," I had the shoe in the bag and he was laughing. He's like, every woman does this. And I was like, “Oh, why are you going to kill your feet?” And I put them on for the interview and photos and stuff. And then before I left, I quickly changed my shoes again and he just thought that was hilarious. And I said men don't understand a lot of these really beautiful shoes. And I love a beautiful shoe, are not shoes you can walk in the city and be comfortable. And I'm all about-- I'm just at a stage in my life where comfort is important, fashion is important, but there is a point to which I'm like, I'm not going to go down an elevator, walk across a bunch of concrete, try to flag down a car, and have to do that in four-and-a-half-inch heels. I'm gotten very practical.

Melanie Avalon: Also, the thing that related to that, that men don't understand, the getting ready process. It's so funny. I went-- Oh, it was fabulous. I went to this event at the Georgia Aquarium. It was called Aqua Vino so it was wine tastings and dueling pianos and an auction. So, I was supposed to go with my dad. But this happened right after all of the hurricane stuff that I talked about last week. And he was just really stressed and wasn't feeling up to it. And thanks, dad, you let me know like right before. I was like, who can I find to go with me? And I was like, well, it has to be a guy because no girl would be able to get ready at this last minute. So I went with my cousin, it was really fun. Although I got so many DMs about my date, I was like, "It's not a date."

Cynthia Thurlow: Nope, Melanie. This is my cousin. That's on Wednesday night.

Melanie Avalon: A decade younger than me.

Cynthia Thurlow: Yeah, my cousin and I went out with him and I was laughing because he's super tall. And, he has a wonderful girlfriend who wasn't able to make the dinner. And we ended up going to this French bistro place and it was fantastic. We both had an amazing steak and I was saying to him I was I forget how tall you are, you are a foot taller than me. I look like a midget standing next to you.

Melanie Avalon: Good times. Some women do not like dressing up, which I will never understand.

Cynthia Thurlow: No, I'm a total girly girl. I mean, I'm all about the details.

Melanie Avalon: I live for it.

Cynthia Thurlow: I'm all about the details and it totally makes a difference.

Melanie Avalon: Especially traveling, it's so stressful for me and I don't like doing it. But if there is any chance of getting me there be like well, there is a formal or black-tie thing. I'll be like, okay, maybe. So, yes. Well, okay, two quick announcements before we jump in. I mentioned both of these last weeks. There is an amazing online conference summit thing called How She Grew. It's by a few influencers, including Noelle Tarr, who is the co-host of the Well-Fed Women Podcast and one of my really, really, good friends. And I am a speaker in it. Cynthia might be, we're not sure. But it is all about-- really, it's all interviews with successful women and how they grew. So how they're doing what they're doing with their businesses, very practical, helpful information to just like learn how these women did and do what they're doing. You can go to melanieavalon.com/howshegrew, if Cynthia is doing it, you can go to cynthiathurlow.com/howshegrew. This episode airs October 24th, up until November 1st, they will have a pre-sale discount. So, use that link now to snag that discount.

And then, the second thing I want to talk about, I talked about this last week as well but as of this recording right now, the episode that is airing on Melanie Avalon Biohacking Podcast is with Dr. Karen Becker for her book called The Forever Dog. Definitely, friends, even if you don't have pets, listen to it. But if you do have pets, listen to this episode. This is actually fun fact. My editor who edits the show, he never comments, I just send him the episode he sends it back edited. He never ever makes a comment about the content for this episode. He literally wrote out like, wow, this was one of the most amazing things I've ever listened to. And so many people have told me that. It's mind-blowing if you care? If you are concerned with the health of your pets, listen to it. All of that to say I think what we feed our pets is really, really important. And I'm thrilled because there is a new company called Yummers. And I think I'm really good friends with the co-founder Rebecca. She actually co-founded it with Antoni Porowski from Queer Eye for the Straight Guy and his boyfriend, Kevin. But they actually make really incredible healthy toppers for dogs and cats. Literally no problematic additives, just the good stuff, they have like, liver supplement toppers, chicken toppers.

One of the problems with conventional pet food is that they include all of these natural flavors and enhancers to make the pets really want to eat it. And that pet food really ends up commercial pet food. I mean, it's shocking. It's basically the equivalent. This is what Dr. Karen Becker was talking about. It's the equivalent of eating breakfast cereal for like every single meal of your life. So, like an entirely processed diet, fake, low moisture, not the correct macronutrients to support health it's really, really, a problem. And they use these natural flavors to make the pets basically addicted to it. Yummers uses real food ingredients that have that same palatability effect for the dogs and cats so they love it and it's super healthy. My mom's puppy, Mia, loves it, my sister's cat Jackie loves it. So, definitely check it out. I'm excited to see the future of the company because they might have more products in the future but they have a lot right now as well. So, you can go to yummerspets.com. That's Y-U-M-M-E-R-S-P-E-T-S dot com. And you can use the coupon code, MELANIEAVALON, to get a discount site wide.

Cynthia Thurlow: There are many things I love about the fall. The crisp cool weather, the warm, cozy fall flavors, all of the festive holidays coming up. One thing I don't love though is the constantly growing to-do list that seems to come with the fall season. Shuttling my kids to various activities combined with all of the prep work for holidays can feel like another full-time job on top of my actual job. I know I'm not alone in this. That's why the Prep Dish is the best way for busy people to get healthy meals on the table without stress. Subscribers receive an email every week with an organized grocery list and instructions for prepping meals ahead of time. This means dinnertime is super quick and easy every day. And if you think you don't have time to meal prep, I used to think the same thing. But with the Prep Dish super-fast meal plans I can prep five healthy dinners in just one hour. Trust me that one hour of meal prep pretty much saves my sanity for the rest of the week. It is 100% worth it. If you want to serve meals like these without the stress, the founder Allison is offering listeners a free two-week trial to try it out. You can't beat that. Check out prepdish.com/ifpodcast for this amazing deal. Again, that's prepdish.com/ifpodcast. So, your first two weeks free, this is a total no-brainer. Recent favorites were the slow cooker Moroccan spice chicken with roasted sweet potatoes and kale as well as the bison burgers with caramelized shallots and sauteed asparagus. Again, you can check out prepdish.com/ifpodcast for an amazing deal, giving you a two-week trial to try this out.

Melanie Avalon: Let's jump into questions. Would you like to read the first question?

Cynthia Thurlow: Sure, this is from Becca. Subject is: "Benefiber and psyllium husk pills." “Before I started intermittent fasting, I was taking Benefiber and psyllium husk pills in the morning and before bed, I have continued to do that since I started fasting. I was wondering if I'm breaking the fast with these two things. I have not really been successful at losing any weight. I've been doing intermittent fasting since January. I feel good and my clothes fit better. But it is occurred to me that I may be breaking my fast without realizing it by taking these two things. Any suggestions? Maybe I don't even need the fiber or I should be taking something else instead. Thank you for your help. Becca.”

Melanie Avalon: All right, Becca, I'm really excited about this question because it's something I've been wanting to talk about. Because it's becoming a thing. I know Dave Asprey talks about it in his fasting book. I know Dr. Gundry talks about it, I think in his most recent book, a lot of people have been-- I know she's asking about it breaking the fast but a lot of people I guess, Dave Asprey and Gundry, and maybe some others have talked about the benefits of taking fiber while fasting to not feed you but feed your gut microbiome, which then can create short chain fatty acids from that. That idea does not resonate with me so much. And the reason being is even if fiber is non-nutritive to us, like I said, just now the gut microbiome can break it down and create energy from it. And just on top of that, it's a substance that stimulates the digestive process. even if it doesn't have "calories" to us, it still has to go through that digestive process and stimulate that. I think personally, taking in something that is doing that while fasting, I find it counterintuitive to the concept of fasting. I'm not a fan of fiber during the fast. On top of that, I don't know why you're taking the fiber. You don't say why? I'm wondering if it's just because there is this conventional idea that we need to be taking fiber. I am all about getting fiber from whole foods, I would look at your food choices. And how can you eat fiber-rich fruits and vegetables that really work for you and your digestive system? So those are my thoughts "Oh, she said she's not been successful and losing any weight." I mean, that could be a lot of factors. I don't know that it's the fiber completely, I would look at your food choices in general and the fasting window that you're doing. But those are my thoughts on that. What are your thoughts, Cynthia?

Cynthia Thurlow: Well, I think on a lot of levels, typically Benefiber and psyllium are recommended by traditional allopathic trained providers. For a lot of people, it's to help with constipation, just to include the amount of fiber in their diet, I do agree with you and echo your sentiments about getting fiber from whole food sources. My concerns about Benefiber and psyllium husk is the exposure to glyphosate. For listeners that's a pesticide, herbicide that is most of our crops are exposed to. We know that there is a direct link with developing small intestinal hyperpermeability, which is when we develop leaky gut, foods that you're eating or then you're leaking food particles into the bloodstream, which can set up an inflammatory response and you can become sensitive to the foods that you're eating. From a health provider's perspective that's the first thing I think about, there are definitely other options. I prefer that fiber be taken if you do have to consume it during your feeding window. I do the idea of resistance starch, I actually have a product called Simply Fiber, which has green banana flour in it and potato starch, which are in their clean sources. But I always recommend that people consume those in their feeding window as opposed to in their fasted state.

And I agree with Melanie, that there can be many, many contributing factors to why you're not seeing weight loss. It could be as simple as your macros, meaning insufficient protein, too many of the wrong types of carbs, and inflammatory fats like seed oil, really closely examining what you're eating in your feeding window, and making sure you're getting a sufficient amount of protein in, I say no less than 100 grams a day. I do talk a lot about these types of subjects in my book. I also think about what else are you doing? How's your sleep? What's your stress management style like? Are you lifting weights? What's your gut health like.” There can be many things that can contribute to weight loss resistance or an inability to see weight loss in and of itself. I think there is a lot that could be going on, I would experiment with the types of products you're using. I would try to bump up your non-starchy vegetables to see if that's able to help you in the absence of using Benefiber and psyllium husk and then really getting acquainted with other options that are available to you if you feel you do need those to have a bowel movement, and there are people that benefit from taking supplementation with fiber, but you want to look at the quality of what you're consuming, to make sure it's the least inflammatory choice of all options.

Melanie Avalon: I am so glad you brought up the glyphosate issue. I do think that is such a huge problem. I really think that's a problem, too. I was mentioning earlier how dog food and pet food is eating cereal all day. That's something I think it's probably a lot of huge issue for glyphosate exposure.

Cynthia Thurlow: And it's interesting not to step on your toes while you're speaking. But there was a podcast I did with Jeffrey Smith last fall that to me really opened up my eyes. He's doing a lot of research and a lot of advocacy to help educate people about exposure to glyphosate and genetically modified foods. And we'll include that in the show notes so that that's available for you to learn from. He's a researcher and also an advocate and pretty powerful message. And someone that does it in a way that makes the information accessible and not scary. But certainly, it's a resource that I recommend for people to learn more about so that they're limiting their exposure overall to glyphosate as much as possible.

Melanie Avalon: I'm glad you said that, I really need to bump him up. He's the one that fell through the cracks with us trying to schedule him for the show.

Cynthia Thurlow: And that happens. I mean I think we all realize that happens, especially when you've got a show your Biohacking Podcast where you just get inundated. We do too. I would say, more often than not, we end up turning potential people away because there just isn't- there aren’t enough slots in here to get all the podcasts people in. But yeah, he would be fantastic on your podcast.

Melanie Avalon: Yeah, I really, really want to interview him. I think what happened was he reached out at the height of a lot of the politicalness of COVID. And I wasn't quite sure the extent of his content, and I wasn't sure if it was going to be too controversial for the show. But now after hearing you interview him, really looking at his work now I really want to bring him on. And it's not because I personally, I like to think I'm very open minded. it's not about me, it's more about concerns with podcast, censorship that can happen.

Cynthia Thurlow: Yeah, and we stayed way away from the fray of discussions about the pandemic, and the virus and all those things to stay. He didn't even bring any of that up. I completely understand.

Melanie Avalon: Yes, I'm happy you brought that up. And then I'm so happy you brought up the constipation piece. Because yes, that is a reason that a lot of people take this often. And I wish that I was the type of person that responded well to fiber helping constipation because there are a lot of people who fiber does help constipation. There are also a lot of people who, and I existed for a very long time-- this is a reason that I want to talk about this. I existed in a very long-time experiencing constipation and thinking fiber was the answer and like trying to shove the fiber down my throat. And it just made it much worse. And it took me a long time to really realize that. I just want to encourage people that if they're taking fiber for constipation, and it's not working, they might benefit A, from just not taking extra fiber, B looking at the type of fiber they're taking, so like for me, I do really well with a low-FODMAP diet. So, I eat fiber-rich vegetables that are low in FODMAPs, which are easily fermentable different substrates that can exacerbate gut issues due to fermentation.

That's why people see my stories all the time buying pounds of cucumbers from Costco, like, I do really well with a lot of fiber from cucumbers and blueberries and things like that, so just Becca, if it is constipation related, the fiber may or may not even be helping, I will put out a resource. If you're curious about FODMAPs, you can get my app called Food Sense Guide. It has over 300 foods for 11 potentially problematic compounds that are found in foods so things you may be reacting to based on your personal constitution. It does include FODMAPs. It also includes lectins and gluten and histamine and oxalates and sulfites and all these things. you can get that at melanieavalon.com/foodsenseguide and Cynthia do you have thoughts about Dave Asprey, Gundry, and people who say that you actually should take fiber while fasting to create these short-chain fatty acids?

Cynthia Thurlow: I think there are many different ways to impact short-chain fatty acids and I'm embarrassed to say I know far more about this subject than I'd like to. Just because of my own gut health journey post-- goodness, so many different things including LPS, lipopolysaccharides. I probably had some E. coli, I got a parasite when in Morocco, I've been treated for said parasite and there has been a lot of gut rebuilding, and I think it's going to be a long process. I actually do better when I take-there is actually a product called [unintelligible 00:25:06] and I do better taking that in a fed state. My stomach's just--

Melanie Avalon: What is it?

Cynthia Thurlow: [unintelligible 00:25:11]. I'll have to give you some separate information. It's essentially a fertilizer for the short-chain fatty acids. And my functional medicine practice really likes it. And so, from their perspective, that's a superior option. I think for a lot of people, some of these resistant starches can be very bloating, and you had mentioned, some people are more sensitive to some of these FODMAP-esque properties, some of these carbohydrates. I think on a lot of levels, obviously, Dr. Gundry is an incredible resource. Dave Asprey obviously does his research as well, he's very comprehensive, but I really think it comes down to the beauty of the N of 1, what really works best for you. And the products I take, I take in my feeding window because I then don't get bloating, I then don't have some of those side effects. There is a degree of experimentation that I think can be helpful. I think for some people they're told to take these products on an empty stomach to lessen the likelihood that they are going to have slowed absorption or less likely to interact with other foods or other supplements or medications and I get that, but I think it's all about the individual. And I know we talk a lot about that. But I think each one of us have to do a little bit of experimentation to find out what works best.

Melanie Avalon: Awesome. I love that, same page, alright. Shall we go on to our next question?

Cynthia Thurlow: Absolutely.

Melanie Avalon: This question comes from Samantha. The subject is: Nutrient Timing? And Samantha says, "Hey, ladies, thank you as always for all you do, seriously changing the world for the better." You cover so many great topics, but I'd like to ask more about exercise. I really embrace exercising while fasted which feels great. I usually do light lifestyle exercise, a brisk walk with the dog, house and yard work, sports with my kids. I know I should start doing more lifting and weight-bearing exercise as I'm approaching 40, it's on the list. In past episodes, you’ve spoken about refueling not being an urgent postexercise need. What you do in the 24-hour period is what matters. Also, I love the discussion surrounding the need for protein. I have made protein a focus for me and my family. Recently, I've noticed the phrase nutrient timing. I've heard Cynthia refer to it and today, Dave Asprey. Can you elaborate and discuss, are there certain levels of exercise where the timing does matter more for certain macros pre and post workout? Also, on a side note, my son plays hockey and hates to eat prior. He's only 10 and a strong lean kid. I encourage at least a protein smoothie. Sometimes he accepts and sometimes he refuses, but he has a ferocious appetite for the rest of the day, so I'm not overly concerned. He eats super healthy too and definitely does not lack for energy. But might he benefit from some better nutrient timing? Thanks, sincerely, Samantha in Canada, she also says she is excited for her Lumen delivery this week.

Cynthia Thurlow: Great question, Samantha, thank you for your questions. And I'm glad that you are leaning into the possibility of starting some weight-bearing exercise, strength training is so so important for us. And for anyone that's listening, the more muscle mass we have, the more insulin-sensitive we are. And this becomes even more important as we are getting closer to middle age, in terms of protein and refueling and nutrient timing, obviously with a teenager and I'm assuming your son is, oh he is 10, so he's a preteen, so he's a tween, kids are still growing. And I think it's certainly very important to make sure that they are getting the right types of fuel in around workouts, they're still growing. Hopefully, we are not still growing at this stage of life we're in, protein and carbohydrates around workouts for them. I think for each one of us, and I'll go back to the bio-individuality piece, I think it's very, very important to identify what makes our bodies feel good. Obviously, if you're lifting heavy things, and you're doing intense physical activity, it's going to be more important to how you are timing those food intakes. And if you're intermittent fasting, I get less concerned about people feeling the need to refuel around a workout. Because as we've talked about before, it's more important over a 24-hour period of time, what I get concerned about though is that a lot of women undereat protein, and if you're trying to build muscle, you're trying to lean into metabolic flexibility.

And remember peak bone and muscle mass is our 20s and 30s. if you're 40 you're already at that stage where you're losing some degree of muscle mass and I know on days I lift heavy yesterday was a leg day and it was a punishing leg day, because I had not been lifting heavy the entire week because I was traveling, I did break my fast earlier and I ate more food than I normally do not because I overate, but intrinsically, my body was telling me I needed to have a larger serving of protein, I needed a bit more carbohydrate. And when I talk about nutrient timing, I also like to think about intuitive eating. And not everyone that's listening is at a point where they're able to intuitively eat. I don't want to spend a lot of time focusing on that. But I do want to encourage people to understand that if you are eating to build muscle and you are intermittent fasting, you have to be very careful about when you're eating. And this goes along with not doing these long fasts, not just eating one meal a day, it's very important that you're getting two good-sized portions of protein in in your feeding window, along with the right types of carbohydrates, and healthy fats if they're not already incorporated into your protein source. It sounds like you're doing a lot of the right things. But kids are very different, even my teenagers are still growing. I'm more concerned about them getting their fuel in around their workouts because they are still growing up, so they're still in this massive anabolic phase. I'm on the other end of the spectrum trying to make sure I'm not breaking down my muscle by not giving it enough stimulus and then not giving it the right nutrients over a 24-hour period of time. Melanie, what are your thoughts?

Melanie Avalon: I thought that was great. This was perfect timing because I'd already scheduled this question in the lineup. And then I had been listening to Peter Attia’s, I think his most recent episode, have you listened to it with Don Layman?

Cynthia Thurlow: So good.

Melanie Avalon: Yes. it's episode number 224. The title is Dietary protein: amount needed, ideal timing, quality, and more by Don Layman, PhD. I was excited last night because he started talking answering this question. I was like, yes, it’s perfect. So, interestingly and apparently, he works with Dr. Gabrielle Lyon a lot, which is awesome. He talks about the nutrient timing of protein. And I realize--, okay, she specifically makes it about protein, which in general, nutrient timing, I do believe is speaking to this protein question. Something I did not know until listening to that episode last night. Yes, so protein is key to maintaining muscle, building muscle post workout. He talks about how if you don't achieve a certain amount of protein after the stimulus of working out, you're not going to build muscle, you've got to have at least was it 30 or 50 grams, I'd have to double check. People who just graze on protein in small amounts all day, they made the case that even if you ate the same amount of total protein, if you ate it in small amounts constantly, you wouldn't get those benefits, especially if you're older because there is a slight caveat for children.

Cynthia Thurlow: Your protein needs change as you get older, you actually need more protein, because you may not be capable of breaking it down as efficiently, so I totally agree with you.

Melanie Avalon: Yeah, exactly. That's why I mean, even in the longevity sphere of people who are really steeped in the vegan world, who are proponents of low-protein diets, even they say, after a certain age, I think it's 60, how you do need a higher protein intake. And what it likely comes down to is just the ability of the body to actually utilize that protein. And you can overcome that by adding more protein to the mix. The fascinating thing that I did not know until listening last night was he said, for people who are new to training, resistance training for muscle building for them-- yes, you can always, within 24 hours, the signals that are created from that muscle training lasts for up to 24 hours, you can refeed later with protein. If you're new to training, you will get a better effect within two hours post workout. If you are accustomed to training and you've been doing it for a while, those benefits aren't really there anymore. So basically, the more trained you get, the less important it becomes to eat right after working out.

But if you're new to it, it might be more important to eat right after working out. And I was glad to hear that because I had not heard that before. I had been just saying basically the 24-hour thing, which is still true. But I think that's a really important nuance to understand. Something else he talked about and this relates to the question about the kids is apparently kids having little amounts of protein all throughout the day, they actually can utilize that pretty well and that will benefit them, like protein snacks and just that's going to help them. He said for older populations basically said there is no point, really once you're a certain age you've got to get a concentrated amount of protein. And having a little bit of protein here isn't really going to add anything, like it's not going to create the benefits that you want. If anything, it might just be taxing on the system. He came to the same conclusion that Cynthia said, which was, you definitely want to get at least two big protein-rich meals. And the most important ones are the first and last meal. He did say also that you can counter some of the effects. When you get older and you're struggling with the body really utilizing that protein, that's when it becomes even more important to do things which stimulate the hormones to stimulate muscle protein synthesis. Again, that's resistance training. Even fasting is counterintuitive as it may seem, but maybe not to our audience because we talk about that a lot. Fasting actually does, prime the body to have a growth stimulus once you actually do start eating again, which is super awesome.

Yeah, and then also they talk about, I know, there are a lot of people who follow for various reasons vegetarian and vegan diets. I completely respect everybody's opinion on that and why they do that. If you're doing it purely for health reasons, and not for personal ethical reasons, I would reevaluate that the more and more I learn about animal protein and its role in the human body, and especially listen to this episode with Don Layman, he really makes the case just how much more suited that is to the human body. And it provides the amino acids that we really need. He also talks about the specific amino acids that are key for muscle building, specifically leucine as well as methenamine and those are going to be higher in animal products. And then something else, I did know this, I don't think it's talked about enough in the vegetarian and vegan world. We often will look at herbivore animals and say, well, they're eating all like a plant-based diet. And they have like, they're super muscular, gorillas and cows and things that. What's really important to understand is that they could have a certain type of gut bacteria that actually ferments plant-based protein and fibers. I don't even know if it's necessarily protein. It can ferment is plant substrates into protein compounds that the animal then can use and we don't necessarily do that. I think that's really, really important to keep in mind, that was a tangent, any other protein thoughts.

Cynthia Thurlow: No, I think that the biggest takeaway for everyone irrespective of what nutritional philosophy they embrace is the importance of protein. Protein, protein, protein is so important. And I find after working with thousands and thousands of women, when women tell me what they're eating, more often than not, they're really undereating protein and they're wondering why they can't build muscle. They're wondering why they're losing insulin sensitivity irrespective of the life stage that they're in. And I just remind them, this is really something that we can lean into. And it doesn't mean that you go from eating 40 grams total a day to 100. But it's something you can be diligently work towards every single day to get to a point where you're going to garner the best benefits.

Melanie Avalon: Exactly. Alrighty.

Cynthia Thurlow: Next question.

Melanie Avalon: I will just comment one last thing. She said she was excited for her Lumen delivery, if listeners are curious what that is. Do you have a Lumen?

Cynthia Thurlow: I do?

Melanie Avalon: Yeah, it measures the levels of carbon dioxide in your breath to ascertain if you are burning carbs or fat and then it helps make macronutrient recommendations to help you take charge of your metabolic health. Do you have a code for them, Cynthia?

Cynthia Thurlow: I do. It might be CYNTHIA, will have to double-check them.

Melanie Avalon: Okay, we can put both in the show notes. I know mine is melanieavalon.com/lumen and while it changes around right now the code is MEL M-E-L that gets you $100 off, which is amazing, but sometimes it changes. If you want to check the most recent code, you can actually have a Facebook group for Lumen as well as for CGMs and Biosense, which is a ketone device. So, just go to Facebook and type in Lumen Melanie Avalon, and that should come up. So, Okie Dokie. Shall we go on to our next question?

Cynthia Thurlow: Yes. Our next question is from Moose and the subject is: Struggling with intermittent fasting. “I first learned of intermittent fasting about six months ago when my yoga teacher suggested I check out the Delay Don't Deny Facebook group. I ordered the book since I've also ordered Fast. Feast. Repeat and I'm reading that as well. I have been listening to the podcast also. I've been attempting intermittent fasting since then and did have a hiccup. For a phase I was drinking Laqua because I thought that was allowed but I learned otherwise and quit that several weeks ago. I have been drinking black coffee and water and doing the clean fast, I know no gum, mints, etc., or anything with flavor. But I really struggle with being so hungry and my tummy growling, I have been tracking my fasting and on occasion I make it to 16 hours, but often I get hangry before then. I'm just wondering if this is common since most of the stories I hear on the podcast people share they have no problem. And it was easy for them to go 18-plus hours early on. I feel like a failure and I'm frustrated. I believe in fasting and the health benefits and want to embrace it completely and lose weight. And I'm not in a hurry but I know that what I am doing, only making it 12 to 16 hours is more for maintenance and not weight loss. For reference, I am 5’6” and currently about 170 pounds and 45 years old, I would like to lose at least 25 pounds. Thank you much for any support or advice.”

Melanie Avalon: Thank you for your question and whenever we get a question like this, I always think it's a little bit telling or noteworthy when people tell us about their fasting experience and issues with either hunger or not working, and then there is no mention of what they're eating, so it's just about fasting. And to me that says I think a lot of people look to fasting and they think fasting, all of the magic is in the fasting, but there is much magic in what you're eating as well. And this actually piggybacks pretty nicely off of the question right before this. Because if you're experiencing hunger, addressing what you're eating could possibly help that a lot. So, are you eating a high protein or moderate to high protein diet in your eating window, making sure that you actually are getting in the fuel and the substrates that you need? So, we'll make it much more likely that you won't be as hungry while eating. Also, the actual macros of what you're eating can be really helpful, so some people do really well with low carb, for example, and they find that when they go low carb with their eating choices, it actually really, really helps their hunger in the fasting period. Some people, it's the complete opposite. they try to stick out this low-carb situation, and they just never feel full. And then they add in carbs. And that's magic for them. I personally follow a-- and I always wonder how many people think I'm low carb, I eat a really high-carb, low-fat diet. That's all whole foods, it's really high protein. But I basically eat a ton of like, and I'm not saying everybody should do this, because I think everybody should find what works for them but like, for me what really works is really high protein from fish and shellfish and chicken and steak, lean cuts of all of that. And then, I eat a lot of fruit and it works really well for me, and I do the fasting. But some people do really well with low carb. Their handle is Moose Elk, so Moose Elk, I would look at your eating and what you're doing there. Yeah, I would really look at the eating honestly. Do you have thoughts, Cynthia?

Cynthia Thurlow: I do and I'm not 100% sure if this is a male or a female, I'm going to assume a female and just speak from the perspective of if you've been doing this for six months, and you're still struggling to get to more than 16 hours, then something needs to shift. It may be that you're not eating enough in your feeding window. It could be as simple as you need larger portions of protein which is going to help with satiety like Melanie mentioned there needs to be a degree of experimentation. You're also if you're a female, you're in this perimenopausal range and it is going to get a little more challenging, it does not mean impossible to fuel weight loss because you're having these fluctuations and progesterone and estrogen. This is a perfect example of, really leaning into what's your stress management like, how is your sleep? Are you consuming an anti-inflammatory diet that could be, removing inflammatory foods like gluten, grains, dairy, and yes, dairy can be inflammatory in certain people alcohol, sugar, I would definitely try an elimination diet to see if maybe there is a food that's inflaming you I do find for a lot of perimenopausal women that gluten and dairy, in particular, can be problematic as well as alcohol, making sure you're lifting weights. I don't know if you're doing any weight training that is certainly very important that will help with insulin sensitivity. But I do find that perimenopause is a particularly challenging time. Sometimes people are over fasting and that's driving problems. People are eating too many nuts and too much cheese which is easy to overeat. I think you really just need to look comprehensively at what you're doing and make some adjustments and know that no one should have to white-knuckle fasting. If you're really struggling then I would break your fast and eat.

But I would also really make sure you're eating the food and the meals that you're consuming. Melanie and I are very transparent about the way that we eat. I eat a lot of protein. I generally carb cycle which means I don't eat the same amount of carbohydrates every day. I really like berries a couple of times a week depending on how much I'm lifting, I may have squash or sweet potato. I really try to stay away from grains because they generally don't agree with me. But I think for each one of us, it's leaning into what makes our bodies feel good. I do better with leaner meat and leaner fish than I do with fatty fish and fatty meats. And I've been consistently that way my entire life, but I would encourage you to really, maybe keep a food diary, maybe do a whole 30 to figure out what's going on. And the other thing that I would say is because you're 45, I would make sure you have baseline metabolic health markers done. What's your fasting insulin? Do you have a glucometer? Or do you have a CGM, continuous glucose monitor I am really looking at the nuances and we will link up some of the more popular podcasts I've done talking about perimenopause, one of the top five podcasts this year was with Dr. Tabatha Barber. And we'll include that with the show notes so that you can listen to that at your leisure. But perimenopause is a time when a lot of things have to change. I'm obviously a living example, I tell everyone that you can navigate your 40s and 50s and still be metabolically healthy and flexible. But you have to make changes and that's the most honest answer I can give you.

Melanie Avalon: That was very helpful and very comprehensive. Thank you.

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Melanie Avalon: Shall we go on to our next two questions?

Cynthia Thurlow: Absolutely.

Melanie Avalon: We have two questions from Robin. She says, “I am a 67-year-old female doing IF since August 2021. I'm 5’7”, my starting weight was 188, my current weight is 155, and my goal weight is 145. Number one, what protein powder do you recommend? Can I mix it in Greek yogurt? I find it hard to consume enough protein in my four to eight-hour eating window.” Do you have a recommended protein powder?

Cynthia Thurlow: I do if you tolerate whey, I like MariGold, It's New Zealand small batch whey. They have chocolate malt, they have vanilla, they have unflavored and that's my preferred whey protein. If you're going to mix it, I would do full-fat Greek yogurt. But I would also make sure that that's not the only protein source you're getting in your window. You really should have an eight-hour window to make sure you're getting no less than 35 to 50 grams of protein in boluses. I think that's super important.

Melanie Avalon: Yes, so basically refer to the earlier questions about all of the proteins. I had Dr. David Minkoff on the show. I really like his perfect amino protein powder. If you go to melanieavalon.com/perfectamino, the coupon code MELANIEAVALON will get you a discount. Beyond that, I eat much just real protein, I don't ever eat really protein powders. But if I do eat protein powders, I encourage listeners to look at the ingredients on the protein powders, because there are many on the market and they're full of just gross stuff, like additives and flavors and just things you don't want in your body. So, finding protein powders that are really just the source of the protein is, in my opinion, really ideal. So, that PerfectAmino is literally just aminos essentially. There are some nice grass-fed whey proteins on Amazon that I've ordered before. I also like single ingredient like egg white-type protein powders. And yes, Cynthia said, of course, yes, you can mix it in your yogurt.

Cynthia Thurlow: And that will definitely bump up your protein and MariGold is great. It's a small company and if you use code, CYNTHIA, you'll get free shipping on it. But that's probably my best recommendation. If someone's listening that's plant based. There is a lot of junky plant-based options that are out there, but Food Babe’s Truvani is probably the cleanest that I've seen for people that are looking for a plant-based option. I personally don't love it because it doesn't mix very well. But I've tried everything, everything I've recommended, I've tried including the whey protein, although I have to be careful with that because I'm dairy-free and dairy doesn't always agree with me. But I think if you're tolerating dairy that is a nice option and if you're looking for a lower likelihood of immunity, evoking immune response, you can look at Tera’s whey T-E-R-A, Tera’s whey. They have a sheep milk protein that is super high-quality small batch and you can purchase that pretty readily and easily as well.

Melanie Avalon: And here's a huge question for you, Cynthia. I'm super excited for when you release your creatine powder. So, creatine is an amino acid. Is it something that people use for their protein intake? Or is it a more specific use not really related to protein intake numbers?

Cynthia Thurlow: Yeah, it's an important question. It's to be used in addition too, we know that women's creatine needs to change with their menstrual cycle, they actually increase if you're vegetarian or vegan. And there is a lot of really good research to demonstrate that creatine is absolutely critical with menopausal, perimenopausal women, so there is really no one that doesn't need it to help with ATP production, to help with healthy muscle maintenance, to help with cognition, and brain health. And I was telling Melanie before we started recording that we're getting very close, hopefully next month the creatine will be available and I'm really excited because the more I learn about creatine, the more I realize that we should all be adding this as a supplement. So, you can throw it into things like a smoothie, you can throw it into water, it's going to be very multifunctional and no junk.

Melanie Avalon: I'm so excited especially because I keep hearing people talk about it. And I do think it's really important. I've never personally used it and I can't wait till you have yours because I'm going to integrate it into my personal arsenal.

Cynthia Thurlow: Thank you.

Melanie Avalon: All right, second question from Robin. She says, “I've been on bioidentical hormone replacement therapy since I went through menopause at age 57. I still have a uterus, so I take estrogen and progesterone sublingually as well as topical testosterone. In the past when I took too much estrogen, I bled some, so now I take a lower dose. My gynecologist told me I have a hypersensitive uterus. I've even considered a hysterectomy. I won't have to worry about this. My question, “Can I do bioidentical hormone replacement therapy for life?” And all your podcasts I've listened to on hormones I haven't heard this question addressed. Also, what do you think about a hysterectomy for my situation? Thanks, Melania and Cynthia. I love you ladies. And I'm thankful for you both.” And she is from Florida. I hope all is well with her with that hurricane situation.

Cynthia Thurlow: Exactly. Well, Robin, thank you for your thoughtful question. First and foremost, a lot of the research and this is not medical advice let me just say that upfront, just based on what you've shared. I really oral progesterone that actually is much more protective of the uterus, so that might be something worth discussing with your GYN. I don't think it's so much that you have a hypersensitive uterus. I just think there is a right dose for you. And perhaps you and your GYN have not finetuned that enough yet. Yes, when estrogen and progesterone are not properly balanced, it can cause you to have some bleeding which, of course, is not fun in menopause, of course. In terms of whether or not you can take bioidenticals for life, the research is now suggesting that it is safe to do so. There are just many benefits. I think for a lot of women, they go a period of time greater than three to five years after going through menopause before starting the medications, starting hormone replacement therapy. And there is some research to suggest that the most benefit is garnered when it started within three to-- there is a beautiful three- to five-year window after going into menopause when you've utmost benefit from starting it. But that does not mean if we have a listener who hasn't started it in that window that there are not benefits. We know there are a lot of benefits, especially because we think about brain health, heart health, bone health, cognition, vaginal health, etc. I'm glad that your GYN is comprehensive because you're also on testosterone, which is also very important. And for people that are listening, the more you learn about testosterone and the benefits of that it's very, very important for maintaining healthy body composition.

Although it can be tricky because some healthcare providers do not offer that as an option. Your second question is what do you think about a hysterectomy for your situation? I would have to really be at a point where I was having a lot of bleeding to consider going through a surgical procedure although hysterectomies can now be done through the vagina, so they can be pretty benign. That's probably a better question for your GYN. Some women think it's no big deal to have their uterus removed. Others are very sensitive to having their uterus removed emotionally and otherwise. And so, I think that's a highly personal question. But with dosage adjustments, hopefully, you will not have any more bleeding and that will not be problematic, and you will avoid having to have a surgery. But I'm grateful that it sounds like you've got a very comprehensive GYN that they're so on top of not only your symptoms but helping to take care of your brain, body, bones, and heart in menopause. Melanie, what are your thoughts?

Melanie Avalon: Yeah, just a few quick things. We've talked about this on the show before. But every time the question of bioidentical hormone replacement therapy comes up, I do think it's important to share the information about how a lot of the potential fear surrounding bioidentical hormones was based on studies that have since been reevaluated and that they're potentially misleading in the cancer risks for women related to this, just something to consider. it could be really beneficial for a lot of people and I think a lot of the concerns and fears surrounding it might be based in some misleading data that happened with, was it the Women's Health Initiative?

Cynthia Thurlow: Yeah, that came out in 2002 and we have a whole generation of providers and women who are fearful to take hormone replacement therapy. I did an excellent podcast with doctors Avrum Bluming and Dr. Carol Tavris earlier this year, which we'll link in the show notes. There is a fantastic resource called Why Estrogen Matters. And I have to honestly tell you that that book is life-changing. I can't tell you how frequently I recommend it, not just for other healthcare professionals that I work with and interact with, but also patients. And I think it's very important that women understand that you don't have to white knuckle perimenopause, and menopause, you don't have to suffer. Your quality of life is hugely impacted by replacement of the hormones that you've lost. It does not mean there is anything wrong with you. I think it's all about honoring each woman and what they want to have done. I worry the most about brain health. I should be completely honest with you. We look at women's rates of Alzheimer's, they go up exponentially when they're in menopause, as we're becoming less insulin sensitive. I just did a fantastic podcast with Max Lugavere talking a lot about this and about his trajectory in his career and the impact of his mother's illness on his decision to really lean into cognition and brain health. And really that's become his life's work. And so, I always say to women that each one of us have to make the decision that makes the most sense for us.

But education and empowerment are absolutely critically important. And I would strongly recommend if you're on the fence or you're feeling unsure, or you're working with someone that's not comfortable prescribing hormones that you work with someone that is and a lot of the clinicians that I've done podcasts with and there are many of them. Dr. Tabatha Barber, Dr. Shawn Tassone. Dr. Bluming is, I believe, no longer practicing. But there are many practitioners Dr. Felice Gersh, who's going to come back on the podcast this fall and we're going to talk all about perimenopause and menopause. There are many heart-centered practitioners, who want women to thrive in perimenopause and menopause. You don't have to do it white-knuckling it kind of like this is this reoccurring theme in this podcast? You don't have to white-knuckle fasting and you don't have to white-knuckle going through reverse puberty. Hopefully that's helpful, Robin but I think you're It sounds like you're in very good hands. And I'm very happy to see that.

Melanie Avalon: Thank you for drawing attention to that. Something I haven't even remotely thought about, not having had that experience of perimenopause and menopause. The only other thing I was going to comment on was, the testosterone piece is just something I want to share. It's with the Women's Health Initiative study thing. I mentioned last episode, how I recently had Doc-Koz back on my show for his new book called Get the Func Out which is a really comprehensive look at seven key hormone systems in the body and how to address that. But he actually opens up the book, and we talked about his story on the show. He went on testosterone therapy, so this is for men. We talked about this, like, I don't know why this isn't more well-known apparently if you're a man and you go on testosterone therapy it can actually lead to infertility, at least while you're on it. So, like, while he was on it, it dropped his sperm to like 0, which he didn't even know is a thing and apparently, it's very, very common. And he was able to reverse it by going off of the testosterone and doing a lot of specific nutritional protocols. And he did say he reversed the fertility issue while he is in this period of maybe wanting to have children, but then he did say, once he after-- when he is on the flipside of children, he'll definitely go back on it because it's the best he's ever felt. I asked him about testosterone supplementation in women and he said that he doesn't really see it.

Cynthia Thurlow: Is he a clinician?

Melanie Avalon: Yeah, he's a doctor. Yeah. And then I was talking with one of my other doctor friends about females and this is why I'm just really curious your thoughts on it about testosterone supplementation in women and he was not a fan either. Have you done it in your practice?

Cynthia Thurlow: Well, here's the thing, and this is going to come. This might be the most strongly worded response this entire podcast listener base has ever heard from me. When men are trying to tell women, this is very much part of the patriarchy. Rarely will you hear me sound this firm about this. When men are trying to tell women that testosterone is not important, we actually have more testosterone in our bodies until we go into menopause than we do relative to estrogen. It is in smaller amounts. But it is very important for brain health, for bone health, for muscle health, to somehow suggest that women don't need supplemental testosterone. And obviously, this is prescription. This is not supplementation. Typically, it's in a cream form. I think on a lot of levels when you have women going into menopause, and they're starting to struggle with body composition changes, they're losing muscle mass, it is a direct reflection of this loss of testosterone and testosterone starts to slowly peter off, unlike estrogen that gets almost you get shoved off a cliff. It can be a precipitous drop, as you're in the latter stages of perimenopause. I always with caution when I hear male physicians suggesting that it's not important. That has never been my clinical experience. Most if not all of the male and female physicians that I refer to and work with and interact with that are GYNs. They're very pro-testosterone for the right person. Obviously, most people in the United States, both male and female, that have low testosterone levels, it's a direct reflection of stress because our body has a hormone hierarchy. They can also be a direct reflection of insulin resistance. And you get this aromatization of testosterone to estrogen. That's why you sometimes will see feminization of men, not because they choose to become more feminized, but it's because their testosterone is being aromatized into estrogen. And I think it's highly personal. I do find most in the functional integrative medicine space talk very openly about using testosterone. It's very much a bio-individual thing.

But the more I learn about the way that hormone therapy has been put on hold effectively since the Women's Health Initiative came out, the more I feel it's important for providers to speak out and just say that most of the women that I see fully optimized in perimenopause and menopause are very likely on some degree of testosterone and I'm not talking about pellets? Pellets are wildly unpredictable. I have colleagues that call it 1920s medicine. Now, if you're someone that gets pellets and you feel good on pellets, great, but I find most women feel good for about a week or two, and then their testosterone levels plummet and they don't feel great. But testosterone is needed for a lot of different things in the body. And although I respect the physicians that you've interacted with, I have to politely disagree and say that testosterone therapy is absolutely part of bioidenticals for the proper individual at the right time. I see a lot of people do really well starting with progesterone and then adding in testosterone if it's needed, and then adding in the estrogen piece, but it's really dependent on your labs, how you feel, the symptoms you're experiencing, and finding the right provider to be able to support your body and your needs and your goals in a way that is aligned with what you're looking for?

Melanie Avalon: Thank you for sharing that. Yeah, like, I'm so new to the whole testosterone supplementation. And it was-- it was interesting that within a very small timeframe, I discussed it with two different doctors. And yes, very interesting that it was the male perspective and so that's really valuable information.

Cynthia Thurlow: Yeah, and I never, like anyone that knows me the phrase, the patriarchy never comes out of my mouth. However, it has been my experience, the more I learn about this time period in women's lives, the more that that really becomes apparent. And I think for everyone listening, finding a provider that can meet your needs is absolutely important. There are some really good books and maybe that'll be part of another podcast where we can unpack that a little bit more and just talk about some of the books that I think are very, very helpful for women. But Why Estrogen Matters is a great starting point to have that conversation with your healthcare professional. And quite frankly, I say this a lot, www.ifm.org I have no affiliation with them but those are functionally integrative medicine-trained people. And you can look in your area, there might be people that are practicing gynecologists or there’re internal medicine physicians, and NPs, and PAs that have an interest in women's hormones and women's health and can meet your needs and you don't have to suffer, so that's the big take home as you do not have to suffer in perimenopause and menopause.

Melanie Avalon: I'm really glad I said that because I'm really glad to hear that answer, so that was very valuable. Thank you.

Cynthia Thurlow: You're welcome.

Melanie Avalon: Quick comment on the patriarchy thing. I wish it would be possible to-- because if you use that word, it feels it comes with all of these assumptions about-- I wish we could just acknowledge it when it actually is existing objectively without feelings of a bias or emotions, but there might just be systems that are from a patriarchy type system manifesting especially in things healthcare.

Cynthia Thurlow: I rarely say that so for listeners to understand that it takes a lot to get me fired up about something. And this is definitely a subject that I feel it is going to be part of my life's work and helping to dispel bad information, bad research, bad results that were reported from Women's Health Initiative and how we effectively have an entire generation of clinicians and women who were fearful to prescribe and then fearful to take hormone replacement therapy.

Melanie Avalon: Awesome. While this was very valuable information for listeners, okay, [01:07:40] a few things for listeners before we go. If you would to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. The show notes will be at ifpodcast.com/episode288. Those show notes will have a full transcript, so definitely check that out. It will also have links to everything that we talked about and we talked about a lot of things. And you can follow us on Instagram. We are @ifpodcast and I am @melanieavalon and Cynthia is @cynthia_thurlow_. I think that is all the things. Anything from you, Cynthia, before we go?

Cynthia Thurlow: No, just know that keep the questions coming. We're loving all the variety and we appreciate you and all the listeners’ support. It really means a lot.

Melanie Avalon: I echo all of that completely. While this has been absolutely wonderful and I will talk to you next week.

Cynthia Thurlow: Sounds good.

Melanie Avalon: Bye.

Thank you much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and re-composed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Oct 16

Episode 287: Thyroid Mysteries, Functional Medicine, Gum, Oral Microbiome, Halitosis, Electrolytes, 48 Hour Fasts, And More!

Intermittent Fasting

Welcome to Episode 287 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

LMNT: For Fasting Or Low-Carb Diets Electrolytes Are Key For Relieving Hunger, Cramps, Headaches, Tiredness, And Dizziness. With No Sugar, Artificial Ingredients, Coloring, And Only 2 Grams Of Carbs Per Packet, Try LMNT For Complete And Total Hydration. For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase!

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To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

LMNT: For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase! Learn All About Electrolytes In Episode 237 - Our Interview With Robb Wolf!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

The Melanie Avalon Biohacking Podcast Episode #165 - Dr. Karen Becker

Go To yummerspets.com And Get 10% Off Sitewide With Code MELANIEAVALON!

How She Grew Pre-Sale! 

AUDIBLE: Go To audible.com/ifpodcast Or Text IFPODCAST To 500-500 For A 30 Day Free Trial, Including A Free Audiobook! 

Listener Feedback: Knowles - Thank you!

Listener Q&A: Sandra - Please help me!

Unfunc Your Gut

Listener Q&A: Tracy - Gum

The Melanie Avalon Biohacking Podcast Episode #162 - Danny Grannick (Bristle)

Ep. 153 – Fix Your Mouth/Fix Your Health: Reversing Tooth Decay Naturally with Trina Felber

Primal Life Organics!

JOOVV: For A Limited Time Go To Joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

Listener Q&A: Anna - Fasting, electrolytes and hot, humid weather

Ep. 213 All About Electrolytes: Symptoms, Causes, and Solutions for Electrolyte Imbalance with Robb Wolf

Simply Hydration!

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 287 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time and get ready for The Intermittent Fasting Podcast.

Hi friends, I'm about to tell you how you can get my favorite electrolytes for free. Yes, completely free. And the feedback we have received about LMNT electrolytes from our audience is overwhelming. You guys love LMNT and I'm so excited, because our new offer allows new and returning customers to get free LMNT and on top of that their super popular Grapefruit flavor is back. If you've been having issues with intermittent fasting, electrolytes may just be the thing that you need and/or have you heard of something called the keto flu? Here's the thing. The keto flu is not actually a condition. Keto flu just refers to a bundle of symptoms, headaches, fatigue, muscle cramps, and insomnia that people experience in the early stages of keto dieting. Here's what's going on. When you eat a low-carb diet, your insulin levels drop. Low insulin in turn lowers the production of the hormone aldosterone. Now, aldosterone is made in the kidneys and it helps you retain sodium. So, low aldosterone on a keto diet makes you lose sodium at a rapid rate. And even if you are consciously consuming electrolytes, you might not be getting enough. In particular, you need electrolytes, especially sodium and potassium in order for nerve impulses to properly fire. Electrolytes can easily be depleted while intermittent fasting.

Robb Wolf, who as you guys know is my hero in the holistic health world, worked with the guys at Ketogains to get the exact formulation for electrolyte supplements to formulate LMNT Recharge, so you can maintain ketosis and feel your best. LMNT Recharge has no sugar, no coloring, no artificial ingredients, no junk. They're used by three Navy SEALs teams, they are the official hydration partner to Team USA weightlifting, they're used by multiple NFL teams, and so much more and we have an incredible offer just for our listeners. You can get a free LMNT sample pack that includes all eight flavors. Citrus, watermelon, orange, raspberry, mango chili, lemon, habanero, chocolate, and raw unflavored and the raw unflavored, by the way, is clean fast friendly. You can try them all completely free when you make a purchase at our link, drinklmnt.com/ifpodcast. You can get this offer as a first time and as a returning LMNT customer and I know there are a lot of returning LMNT customers. The feedback I hear from you guys, "loving LMNT" is amazing. LMNT offers no questions asked about refunds on all orders. You won't even have to send it back and this offer is exclusively available only through VIP LMNT partners. You won't find this offer publicly anywhere else. So, again, the link is drinklmnt.com/ifpodcast and we'll put all this information in the show notes.

And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense because these foods affect our hormones and how our bodies store and burn fat but do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting, it's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream and then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup maybe playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That's because ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years. 

Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so you can truly feel good about what you put on and friends, these products really, really work. They are incredible. They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their overnight resurfacing peel and vitamin C serum every single night of my life and their makeup is amazing. Check on my Instagram to see what it looks like. Tina Fey, even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out and you can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well. 

And lastly, if you're thinking of making clean beauty and safe skincare, a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order and we'll put all this information in the show notes. All right, now, back to the show.

Melanie Avalon: Hi, everybody and welcome. This is Episode number 287 of The Intermittent Fasting Podcast. Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hey, Melanie, how are you?

Melanie Avalon: I am good. Can I tell you the crazy hurricane story?

Cynthia Thurlow: Yes, please do.

Melanie Avalon: Oh, my goodness. So, at the time of this recording, Hurricane Ian just happened a few days ago and my family has a condo in Sanibel Island, where it basically landed in Fort Myers, Sanibel Lee County right in that area and they didn't know it was going to land there until-- The county didn't do a mandatory evacuation until 24 hours before, because they thought it was going to hit Tampa. Were you following it, the hurricane? I know you're crazy traveling.

Cynthia Thurlow: Yes, I've been following it because I was initially concerned obviously about all my friends impacted in Florida but I was also concerned I might not make it back from the West Coast. So, we had a very, very turbulent last 30 minutes of my flight on Friday.

Melanie Avalon: Oh, wow. Yeah, I bet. I didn't even think about that. 

Cynthia Thurlow: Yeah, and it's interesting as soon as we got on the plane, the two pilots were former Air Force pilots that had transitioned to the civilian sector and I jokingly said to the person sitting next to me, I was like, "I feel complete confidence because they have dealt with far worse than the impact of Ian coming up the coast." So, lots of turbulence, more than I've had in a long time but we safely landed and I'm grateful to have gotten home on Friday.

Melanie Avalon: Random quick sidenote about planes. When I flew to Austin on the way back after we landed, they told us that-- Basically, they were like, "Congratulations, we were actually testing autopilot to land and it was a success." And they tried to phrase it like it was like congrats and everybody on the plane was like, [laughs] "Is that a good thing?" I told my family and they're like, “We have never--” "Have you experienced that on a plane after the fact they tell you that?”

Cynthia Thurlow: Well, I think there are probably a lot of things just like when I worked in healthcare that go on that you have no idea is going on behind the scenes and then you just blissfully and naively get off the plane and you're like, "All is good." In the past week, I've been up and back to New York and then across the country to LA and back, and one of the legs of my flight, I think it was Denver to LA, there was some type of "dent" in the side of the airplane and so, we had a 90-minute ground delay while maintenance determined if it was "safe to fly." So, it was one of those things where I was like, "Dang, I don't want to not fly today." But obviously, safety is of the utmost importance and so we ended up flying without any issues but it was funny how they were talking about this dent and I'm thinking, "Is it a big dent, a little dent?" They didn't identify how large or small it was, but I'm grateful someone was paying attention.

Melanie Avalon: Wow. I remember my piano teacher growing up, she said one time on her flight, they were flying and then they didn't land. They were just circling and they told them it was because they knew something had fallen off the plane, but they weren't sure what it was. [laughs] So, then they found out later it was a hubcap to the wheel. So, it was fine. But can you imagine--?

Cynthia Thurlow: No, I can't. Sometimes, again, it goes back to that being somewhat blissfully naive to the interworkings of aviation is probably to my benefit, because I think both of us are probably very similar. I'm such a critical thinker. I'd be like, "What impact would that make? Would that impact drag on the plane? What would go on?" And I made the mistake of watching-- Anyone that's listening, don't watch the documentary about Boeing.

Melanie Avalon: Wait, wait, wait, is that the one where the pilot got sucked out the window? 

Cynthia Thurlow: No, this was about how Boeing was bought out and their safety and maintenance strategies changed enormously when they were bought out. And then there were two major airline disasters. I was saying to my husband, I was like, "Why did I--?" Because I tend to be a documentary nerd anyway and I was like, "Oh, I started to watch it." And then I was like, "I probably should not be watching this on a plane at the same time." Probably, not a good idea. Yeah, it wasn't about anyone getting sucked out but there were two major crashes in the late 2018, 2019 that were related to Boeing not wanting to properly train the pilots in this system that was helping the plane, like stayed kind of equal. Again, I'm not a pilot so I'm probably not explaining this properly, but there were some technical things that had changed about the newer planes that Boeing did not disclose.

Melanie Avalon: Wow, the pilot sucked out one scarred me for life. The window broke, literally the pilot got sucked out the window. I don't even know the details. I have to rewatch it. It was some United flight. But then the crazy thing is, they landed the plane because of the oxygen levels dropping from the window, it made the pilots be at the level of being drunk. They landed the plane successfully and the pilots survived. They've been holding on to him and he was outside the window, scarred me for life.

Cynthia Thurlow: Those were some good friends.

Melanie Avalon: I know. In any case, the hurricane. My mom had decided to stay on the island. My sister had evacuated and the night before it hit when we all realized it was going to hit the island, she was wanting to drive back after all, mostly, because she was worried about the car. My dad's car getting ruined in the garage and we all convinced her to stay, because we didn't want her to leave and get stuck driving in the middle of the hurricane. In retrospect, maybe she should have left because maybe she would have gotten far enough away. In any case, the hurricane hit Sanibel. Actually, I bet a lot of listeners have been to Sanibel, because I've been posting about this and I've been getting so many DMs of people who have been to Sanibel or knew about it. It’s this beautiful-- Well, it was. This beautiful, gorgeous island, 14 miles long, one mile wide, really nice restaurants and no streetlights. Like an old town feel, but really nice. 

So, in any case, that's where the hurricane hit and my mom said, the water-- She was on the third story at the condo. She said the water went up past the garage up to the first story of the condo. We think it was probably about 18-feet high, the water. She actually thought she was going to die. This is so sad. She said she was in the closet because she had our puppy and my sister's cat and she said that she thought she was going to die, and she was writing us all letters, and she put out a lot of food for the pets hoping they would survive. It's so sad. So, that was that night. And then we weren't really hearing from her because the cell signal was so spotty. And then the causeway to Sanibel, it broke. It's gone, half of it. The island got shut off from the mainland, covered in water. We weren't really able to get in touch with her. Most of the boats in Florida are all wrecked. All the ones that were basically on-- Not in Florida, but Fort Myers in that area and on top of that you couldn't even barely get down there. We were trying to find a rescue mission. Literally, all day, it was the craziest day of my life.

I'm friends with Kirk Parsley. I've had him on The Melanie Avalon Biohacking Podcast. He's a sleep doctor and a Navy SEALs. He connected us to this group of military and SEALs that help people with rescue-type missions. You can hire them ala carte to help you with things and they were so nice. The woman in charge, Stacy, shoutout to Stacey. She found us this guy, Captain Dave in Fort Myers who had a pontoon boat and so, the few times we were able to vaguely get a text through to my mom, which on top of that-- Oh, this is a good lesson for people, this might help somebody. If you're in a situation where you don't have good cell service like this situation, if you have your phone, set on iMessage, then you'll have a lot of issues getting through texts because it'll wait for iMessage to be online. Basically, my mom could only text my aunt, because she has Android and she wasn't realizing it was her phone settings. So, we were having to text her through my aunt and we're trying to communicate with her that she had to be on the beach the next morning at 8 AM and wave a signal. We didn't know she was going to be on the beach. It was literally the craziest thing.

And then Captain Dave in his pontoon boat, [chuckles] the next day went across the ocean to Sanibel with two other guys and picked up my mom and three neighbors and rescued them and my sister and brother had driven down the day before, so they picked her up. It's just insane and it's so crazy to see pictures of the island and it's so weird, because my whole childhood was basically there and to know that it's all just gone. It's very, very weird feeling. I'm so grateful. Last I checked, I think, I don't know what the death count is at, I think it's in the 60s, not just Sanibel, but the whole area where it hit. My heart goes out to everybody and it's just a crazy experience. So, I had to share that.

Cynthia Thurlow: No, I'm so glad that your mom was able to be rescued along with some of her neighbors. I have a lot of friends in the Naples area and the photos-- 

Melanie Avalon: Yes, that's where it hit too. 

Cynthia Thurlow: I have friends that left Northern Virginia, and were building houses down there, and they lost everything. They lost their cars, they lost their homes, the photos are just really, really heartbreaking. The irony is, one of my Hopkins nurse friends lives down there and her house was okay, but another friend of mine that I've known for, gosh like 15 years, I was able to connect both of them and I just think for all of us that are so fortunate that we're not adversely impacted by these storms, we owe it to ourselves as community members to try to find ways to help and donate. If you can donate money, donate time, or working with local organizations, because all of us probably know people that have been impacted. My mentor and the head of my mastermind, she actually had to evacuate and I've been at her home and-- [crosstalk] 

Melanie Avalon: Where is she?

Cynthia Thurlow: Tampa. A lot of people just picked up and took their pets and left because they had to. They were so close to the water or live on the water and gosh, there're so many people impacted but in terms of your mom's story, of course, it sounds like an incredible-- This is where networking and podcasting is so helpful. I'm glad that Kirk was able to get you connected individuals that could get her to a safe place and neighbors as well, and pets. Can't forget the pets.

Melanie Avalon: I'm so grateful. Yeah, that's the other thing that I forgot. In the condo, we had hurricane shutters. They actually stayed intact. Actually, the inside of our condo is okay, but almost every single unit, the shutters blew in and it's a situation where basically, the whole wall facing the ocean is window shutters. All the other condo units, they blew in. I can't even imagine if that had happened. But my mom, like she said, she thought she was going to die, because the whole building was shaking. Super grateful. I know from all the DMs. I got that a lot of people had situations, where they had friends or they weren't hearing from people and when we air this it will have been a while ago.

Cynthia Thurlow: I'm so glad that she's safe. I know we were texting over the weekend, and I was crossing my fingers, and grateful to know that there was a happy ending.

Melanie Avalon: Yes, indeed. So, anything you'd like to share before you jump in? I know you've been crazy with travels.

Cynthia Thurlow: Yeah, I've had some really cool professional things. I was able to speak at an event at Lincoln Center and having grown up in New Jersey, Lincoln Center is a really special part of Manhattan, and then I flew out to the West Coast earlier this past week and was on two of the biggest podcasts that are out there, not just in the health and wellness space, but two of the big ones and that was such a surreal experience and they were both incredibly humble, warm, made me feel incredibly welcome. I left hugging both of them and really just feel incredibly grateful. It's such a cool experience. I have a cousin who works at USC, so I got to see him and then some other friends for dinner the last night I was there but yeah, it was a whirlwind week between New York and LA. Literally, it was home for a day and then flew back out again.

Melanie Avalon: I can't wait to personally hear more about it. I know you literally texted me about it the day of operation. What my siblings and I are calling the operation delta-alpha, which stands for a name we've given my mom for her decision to stay on the island. You were texting me all during that, so I didn't really get to absorb it. I can't wait to hear more later about the actual experience because I'm really excited and happy for you. It's awesome.

Cynthia Thurlow: Yeah. Here's the thing. For anyone that's listening, I think vision boarding is really important, because the process of manifestation without going down a gigantic rabbit hole is just such a cool thing. Because one of these people was on my vision board from five years ago. When I was finished recording with him, and I was leaving, and he and his team were wonderful, and I just said, "I have to let you know, you've been on my vision board for five years and I knew one day I would meet you," and this is just such an incredible, incredible experience. I'm so very grateful and appreciative. Then I walked outside and flagged down an Uber [laughs] went back to my hotel. So, yeah, it was really cool. Really, really cool.

Melanie Avalon: Just one comment I love, because especially when you have a career like us, where it's very nebulous, because it's all creative and creating your own path and there's not milestones, per se. So, it's really nice to have those moments, things that were personal milestones. That's amazing. Have you had him on your show?

Cynthia Thurlow: No. I'll have Sean Stephenson on my show in November and I think Lewis is not doing a ton of press right now. He's got a book coming out in 2023. No, I've haven't had him on. That would be a gigantic unicorn guest. 

Melanie Avalon: Yeah. It's amazing. 

Cynthia Thurlow: Yeah. For context, Lewis House is who I'm talking about, but he could not have been more gracious and just how can I help you, very heart centered and very genuine. He's done the work. You can tell it. And yeah, I sit back and complete-- I'm just feeling very, very-- There's no other way to describe it. And I'm a pretty articulate person just sitting in complete gratitude. There's not a lot wrong in the world right now for me.

Melanie Avalon: It's amazing. Well, I have two quick announcements before we jump in. Speaking of pets, I will talk more about this next week, but there's a company called Yummers that I am obsessed with. If you listen to my episode that I aired with Dr. Karen Becker, which is one of my favorite episodes to date on The Melanie Avalon Biohacking Podcast, you will really, truly realize the importance of what we feed our pets and so, Yummers makes amazing toppings for your pets that are completely like everything I would design there. No problematic additives, just healthy, just the good stuff. And the founder is a personal friend and so, I just wanted to share it with you, guys. By the way, I was talking about our cat and dog that survived the hurricane. They love Yummers. So, I do have a link. You can actually get 10% off site wide with the code, MELANIEAVALON. That's at yummerspets.com. Y-U-M-M-E-R-S-P-E-T-S dot com. I'm going to talk about it more at length probably next episode. 

And then second announcement before we jump in. There is a summit coming up called ‘How She Grew.’ It's being hosted by five different influencers but one of them is my dear, dear friend Noelle Tarr, who cohost The Well-Fed Women Podcast. Noelle's one of my bestest friends and I've been listening to Well-Fed Women, which used to be called the Paleo Women Podcast, literally since it started years ago. It's one of my favorite shows and I still listen to it every week. Noelle created ‘How She Grew.’ The purpose of it is for women who really want to learn about creating their own business and just doing something like themselves that out of-- Actually, I don't even know, if it might be traditional jobs as well, but basically they just interview a lot of really successful women. I'm doing an episode. Cynthia might be, we're not sure we were talking before this. But in any case, I think it'd be super, super valuable. So, there is a prelaunch discount. I'm going to make a redirect. If you go to melanieavalon.com/howshegrew-- And then we don't know if Cynthia is doing it. We’ll put in your redirect. It might not be there. Would it be like cynthiathurlow.com/howshegrew?

Cynthia Thurlow: Probably.

Melanie Avalon: Okay. You can try that too. [laughs] But in any case, I think they're going to have the basic one, where you can get just the interviews and I think it's going to be around 199. And then before November 1st for premium access, which will include the videos, lot of bonuses, a Facebook group, lot of cool stuff that'll be $2.27 and then it goes up in price after November 1st. So, snag it now. You can use those two links that we just gave. I really do think it'll be really valuable. I had a really great conversation with Noelle. Ours is sort of focused on podcasting and influencer stuff, but yes.

With my super busy schedule and how I'm always on the go, I don't have a ton of time to do the things I want to do like reading and that's why I love Audible. Audible offers an incredible selection of audiobooks across every genre from bestsellers and new releases to celebrity memoirs, mysteries and thrillers, motivation, wellness, business, and more. Recent favorite is Jennifer Worth, Call the Midwife. As an Audible member, you can choose one title a month to keep from their entire catalogue, including the latest bestsellers and new releases. All Audible members get access to a growing selection of audiobooks, Audible originals and podcasts that are included with membership. You can listen to all you want and more get added every month. My personal favorite way to enjoy Audible is while driving in my car and also, while at the gym. Let Audible help you discover new ways to laugh, be inspired or be entertained. New members can try it for free for 30 days. Visit audible.com/ifpodcast or text IFPODCAST to 500-500. That's audible.com/ifpodcast or text IFPODCAST to 500-500 to try Audible free for 30 days. audible.com/ifpodcast. 

Melanie Avalon: Shall we jump in to fasting stuff? 

Cynthia Thurlow: Absolutely. We've got some feedback and it says, "Thank you, Melanie and Cynthia. I was so surprised to hear my name and question yesterday on the podcast. I really appreciate your in-depth answers and will be relistening to make sure I got it all. We had house guests last weekend and I ate breakfast to be convivial and was starving the rest of the day. I really prefer skipping breakfast and I'm happy to know that I'm not damaging my health by doing so. Thanks for all you do. Fondly, Knowles." Knowles, we're so glad that you submitted a question and we're even more appreciative to know that you found so much value in our responses.

Melanie Avalon: Yeah. And one thing I just like about hearing this back from Knowles is, so, obviously, her issue or her question had to do with really feeling like she had to eat breakfast. That did not suit her life. It made her more hungry. It's so interesting to me that people, because I know I'm this way personally. I struggle with autonomy. I need somebody to tell me that it's okay. This is probably a character trait that I should work on with my therapist. But I find it so interesting that people need to know-- Especially, with intermittent fasting, they just need somebody to tell them that the decision that they intuitively know is okay and right, is okay and right. So, I do want to empower people to feel what they're doing is okay but I like that we cannot provide that service, but that we can help out in that aspect to reassure people that they should listen to their bodies and do what feels right. And if they want to skip breakfast even in a social situation, that is okay.

Cynthia Thurlow: Exactly. And I think the other piece of it is, more often than not, when people are uncomfortable with the decisions that we make for our own betterment or our own self-improvement, it's really a mirror of their own issues and not your own. If people are bothered by the fact that you fast or you don't eat breakfast, feel comfortable and confident that you were doing what is aligned and most in step with supporting you and your body and don't feel you have to over explain yourself. That's the other thing and I don't know if it's life stage of where I am, but I'm definitely in a stage where I no longer feel I have to explain myself. I tried to just be respectful and respond to people's questions or concerns but by the same token, one of the things that I think we as a group of clinicians have not talked to our patients enough about consistently is the value in the power of N of one. Meaning, you as an individual and doing a degree of experimentation to find what works best for you, your lifestyle, etc.

Melanie Avalon: Exactly. I love that. All right, shall we jump into some questions?

Cynthia Thurlow: Absolutely. 

Melanie Avalon: To start things off, we have a question from Sandra and the subject is: "Please help me." And Sandra says, "Hello, beautiful ladies, first of all thank you so much for the amazing work you do with this podcast. I absolutely love it. Love the chit chat, the tangents, the honesty, and your personalities. I'm 29 and according to my blood work, perfectly healthy and yet I have all the symptoms of someone with hypothyroidism. I started IF exactly a year ago on March 14th, 2019 and had great results not only a weight loss, but also in my general wellbeing until this February. In the past one month and a half, I've gained the 25 pounds I had lost. I'm 5'1" and I'm weighing 135 pounds. I know the number on the balance isn't everything, but my pants don't fit me anymore and I feel extremely bloated, heavy, tired, and sluggish. I'm also presenting symptoms of IBS, bloating, abdominal pain, and constipation. I'm a Mexican student living and working in California. I've been to see several doctors including naturopaths and no one seems to know what's wrong with me. All my tests come back normal, but I feel so awful it's hard to function. I really don't know what to do and would love some guidance, advice, and help. Thank you so much. Love, Sandra."

Cynthia Thurlow: Oh, Sandra, goodness, there is clearly something going on. If you have gained 25 pounds in a short amount of time, I think more so than anything, the fact that you sound from what you've described that you sound like classic symptoms of potentially an underactive thyroid. I think that you need to find an integrative medicine or functional medicine doctor, MD, Nurse Practitioner, PA in your area. When people say, everything's normal, that to me sounds very aligned with an allopathic perspective. And so, the reason why I'm encouraging you to not settle with people telling you what's going on is normal. It is not normal because there's some degree of metabolic imbalance that's going on that has precipitated you feeling so poorly and it could be any number of things, which is far beyond the context of this podcast and that's why I think if you go to and I have no affiliation with IFM, but www.ifm.org, you can put in your zip code or your part of California that you live in, and you can find providers in your area that have special testing to look beyond just the traditional labs and labs that are covered by insurance, but looking at a full thyroid panel, looking at an iron panel, looking to see what else might be going, looking at your sex hormones, your blood counts, your chemistry panels, really diving into what's going on, probably doing some potential stool testing, food sensitivity testing, etc., but I would not settle for someone telling you that everything is normal if you feel that poorly. And to me, it's almost the analogy of peeling an onion. There're probably multiple layers of things that could potentially be contributing to one another, but you need an absolutely thorough diagnostic evaluation. Again, IFM, no affiliation with them, but that's generally where I send people that live in parts of the country, where perhaps I don't know have a personal recommendation in their area, but there's absolutely a provider that can help you.

Melanie Avalon: Awesome. Yeah, I think that's an amazing resource and I really empathize with you, Sandra, because it's so common and it's so confusing, and I've been there and often have existed there, which is just not knowing and not being able to find somebody who can help you and just not knowing what the source is. And I remember for me, especially when I was at the really-- And I'd be curious of your thoughts on this, Cynthia. When I was at my really low point with my energy levels and everything I was experiencing and before I knew exactly what was going on, I remember on the one hand thinking like, "I should be able to just intuitively figure this out." If I just listen to my body, I should be able to eat the foods that nourish me, and I should be able to sleep, and I should be able to rest, and I should be able to get better. 

But looking back, I actually don't-- I don't know that I could have intuitively lived my way out of my situation, because for me it ended up being severe anemia to the point of hospitalization and ended up being mercury toxicity, thyroid issues all along the way and I guess, I just say that to say the importance of finding a practitioner who will test and find the things that are happening. Does that question make sense? I've been haunted by this question for so long, like, feeling like you should be able to just intuitively get better versus needing to test and work with somebody.

Cynthia Thurlow: I'm probably not the best person to ask that up, because I come from a clinical background and to me, as she's describing what's happening, I'm thinking a really thorough medical history is important and then you need testing to backup what you're already thinking. And so, I think for anyone that's listening, even people like myself with as much knowledge as I've had, I definitely have had periods where I've had to humbly surrender and let a practitioner figure it out for me. Intuitive to a point, but then I think we also get to a point where we start second guessing ourselves. I'll give you a good example. 

I've had hypothyroidism for about six years and was doing pretty well till about two years ago when my Nature Throid was taken off the market and many people that are probably listening, they probably have been on a series of different medications. And now, I truly believe I'm working with probably one of the smartest physicians I've ever met in my entire life. And I don't just say that, because I know him personally as well as professionally. And I'm on compounded medication now and he is checking my thyroid levels every two weeks and he has told me, he said, "You have one of the most interesting thyroid panel results I've ever seen." And I was like, "I don't necessarily want to have the most interesting thyroid panel you've ever seen." But I do feel sometimes. we have to wait to work with the people that are going to be able to get us to the next level. 

And so, part of why I'm saying this in the context of answering Sandra's question is really understanding that the right practitioner is out there and it sounds like she's taking account of all the things she's experiencing and now, just needs the right practitioner to help her figure it all out. Really looking at that relationship as a partnership, so that they can work together, because how many people listening irrespective of what age they are are being told exactly these things, you have all these constellation of symptoms, you feel terrible, and you're being told everything's normal. And it's not normal, right? And so, part of this is empowerment and part of this is getting connected to the right people. 

Melanie Avalon: I'm so glad you mentioned that about your experience with the hypothyroidism, especially-- I know I've mentioned my journey and especially the doctor I'm working with now that I started working with because I actually found her under my insurance. Upfront, she actually tested all the things like TSH, free T3, reverse T3, everything and she seemed to really understand. But as we progress, the decisions she's making based on my thyroid medication, they don't make sense. They don't make sense and she also like you're mentioning your practitioner tests every two weeks. She's like, "Well, we'll test in three, or four, or five months." I don't know, after changing your dose if we should wait that long. All that to say, what Cynthia said at the very beginning answering Sandra's question, which I'm not being a good example of right now but the importance of finding somebody who really understands you can work with you. 

I do want to provide a resource actually that might be helpful for Sandra and other listeners. I just interviewed last week. I brought back Doc-Koz. His first book was called Unfunc Your Gut and people loved it. And he has a new book called Get the Func Out. Func is spelled F-U-N-C. It's like a play on functional medicine. That book is very comprehensive and covers basically the seven hormones that he thinks are related to health like fatigue and issue, thyroid related hormones, progesterone, testosterone, cortisol, all these things. It's very, very helpful and eye opening and he actually lists all of the tests that he likes specifically and I think it's just a valuable resource. Or, if you do find a practitioner to work with, especially if it is a conventional doctor under your insurance, it's empowering because you can actually have a list of things that your doctor might be opening to test. So, I'll put a link in the show notes. Actually, by the time this airs, because that book is coming out pretty soon, yeah because this episode comes out the 17th. It will be coming out next week. So, I'll put links to that in the show notes. Okay, shall we go on to our next question?

Cynthia Thurlow: Absolutely. This is from Tracy. Subject is: "Gum." "Hi, ladies. I'm thankful for your guys' podcasts and I think I've converted at least a dozen people since I started back in October. One being my husband, who has blown me out of the water with opening his window on 5 PM or 6 PM and closing it four to five hours later. He looks great and has lost all his pregnancy sympathy weight. He calls it ha-ha and then my mom who is down 30 to 40 pounds in the last four to five months or so with an average 12 to six-window. I am a hairstylist and I'm constantly in people's faces. I start work around 1 PM or 2 PM a couple days a week and much earlier on Saturdays. 

I prefer to chew gum throughout the day to make sure I'm not breathing bad breath at my clients. I brush my teeth often, but I just can't handle the thought of not having a piece of gum in my mouth while I'm talking away. I've tried the WOW Drops and peppermint essential oil, but it is just not the same in at times I'm working without any breaks for hours at a time. Would it be beneficial at all if I chewed gum a couple of hours before opening my window while working or would it just be the same as having cream in my coffee at the same time? I love to advocate the clean fast. I have kept 20 pounds off back to pre-baby weight thanks to intermittent fasting and working out three to four days a week as of having a baby in late June, but would like to continue to keep losing maybe another 10 to 15 pounds. I've been staying around the same size for a few months now. I know I lose weight when I can fast for longer periods of time consistently, but I'm struggling with workday fasting. I used to start work later in the day. So, this was not an issue. 

I find myself opening my window with food earlier on work days and leaving it open way past the eight hours, just so I can chew gum and eat after my day is over with my husband. I could care less about chewing gum when I'm not at work and closing my window early in the evening just doesn't work for me. My perfect scenario would be a 19:5 opening my window on 3 PM or 4 PM. Thank you and sorry, if this is a no brainer. I just wanted to know you guys’ thoughts and if you had other ideas on how to work around this."

Melanie Avalon: Awesome. Well, thank you, Tracy for your question. I'm just reading it. Cynthia, are you reading this as the gum is triggering her hunger, making her want to open her window earlier to eat? Is that how you're reading this?

Cynthia Thurlow: I think I can read it from two angles that or that she wants to chew gum because the purpose of the gum is to keep her breath smelling fresh for her customers and her clients and we could unpack that a couple different ways.

Melanie Avalon: Yeah, because she says, I find myself opening my window with food earlier on workdays and leaving it open way past the eight hours, just so I can chew gum and eat after my day is over. I'm not understanding is, is she opening the window with food, so she can chew the gum or is she chewing the gum which makes her hungry, which makes her open the window with food?

Cynthia Thurlow: I think it's more the latter. That's my assumption.

Melanie Avalon: Okay. In any case, I guess, regardless of the details, the gum situation is making her open her window earlier for whatever reason. So, Tracy, I as well have a slight borderline obsession with clean breath. And there's a reason because of this. I think I've shared this story on the podcast before. I don't know, I think I have. No, it was right after graduating, I went on a date with a man and I had gone through like a garlic phase. I just discovered garlic and I didn't realize how intense garlic was. And this was a first date with this guy and it was blind. I think he hit on me in Costco and asked me out. I don't know, but we had mutual friends. I went out on one date and then at the end, he tried to kiss me and I don't, in case boys are wondering, I'm not going to kiss you on the first date. So, I refused that kiss and then he made a comment about how I had had garlic earlier and then he said, but I should be flattered that he still wanted to kiss me even though of the garlic. 

In any case, that was a little bit traumatic for me and ever since then I have been uber obsessed with fresh breath. It's a problem. And it's the reason that I started using that peppermint oil spray that she talks about which we've started a fandom with on the show. We'll put links to it in the show notes. And it's on ifpodcast/stuffwelike. And I realized Tracy said, it doesn't really work for her, but it's a game changer for me. I basically just put a few drops of organic food grade peppermint essential oil, and water in these adorable little glass bottles that they have on Amazon and I keep those in my purse. Those really work for me. They're way more potent than chewing gum and they just clear out my whole head. 

All of that to say, Tracy, I know, you think gum is the only answer to the bad breath situation. But I would challenge you that gum is not the only answer. There are other answers here. One, it has actually nothing to do with the actual freshening of the breath. What you're eating and the timing of it and how you're digesting can have a huge effect on your breath. And also, obviously, the garlic is an example of something that stays with you, but there are things that you eat that because of those sulfur compounds and things like that will have a lasting effect on your breath the next day. I personally know that based on what I'm eating, it can affect how my breath smells. 

Something that might be really, really helpful. I recently aired an episode with a company called Bristle. They are incredible. They test your oral microbiome, which nobody is testing the oral microbiome. I’m becoming obsessed with this company, because I had thought for a long time that the oral microbiome was a big deal and nobody was talking about it and I'm pretty-- The more I learn about it through Bristle, the more I'm realizing that was the case. I aired an episode with Danny Grannick, who is one of the founders. I'll put a link to that in the show notes. It is the most eye-opening conversation ever about the oral microbiome. 

If you do Bristle, they'll test your oral microbiome and then it's all science based and they make personalized recommendations based on your gut bacteria. You basically get a list of results and it will show how your personal gut bacteria correlates to things like cavities, and gum disease, and halitosis, which is bad breath and then it provides personalized recommendations, not for products made by them, just ingredients that can address that. I would get that and I would follow the recommendations for the halitosis, because there might be some products that can work for you and I know the products, I know there can be a lot of debate about the toxicity of mouthwashes and things like that, but I think it's a very complicated situation and I think especially if you listen to my episode with Danny, you'll realize how there are multiple approaches to this, like, food, diet also products may work. 

I know, for example, I actually really like TheraBreath, the one that is unflavored and doesn't have any sweeteners or anything in it but it has an ingredient in it that specifically-- this is such a casual way of describing it. It deactivates the sulfur-producing bacteria, I think. I'm probably not correctly communicating what it does. But in any case, it has a lasting effect that really for me lasts all day. So, that might be something to try. All of that said, I will get Bristle-- Oh, if you'd like a discount, you can go to melanieavalon.com/bristle, B-R-I-S-T-L-E and the coupon code, MELANIEAVALON will get you a discount. I had to ask them for this. It will actually get you a discount on their subscriptions as well, which those are already discounted. So, that's actually a really good route to go, especially if you think you're going to be retesting. 

I would do that. I would reconsider that maybe you don't have to be chewing gum. I know you said you don't like the peppermint spray. Maybe if you just reevaluate and try it again. I know she said she doesn't like it. I just think there are other options than chewing gum. As far as if the gum actually breaks the fast, there're a lot of ingredients and different gums, a lot of them can be sweet and just the chewing process, I don't know that our brains know that when we're chewing gum, that it's not food. It's a very food stimulating process. It's definitely sending mixed signals to our body. I'm not a fan of chewing gum during the fast. And you're experiencing the effects of that. You're saying, it makes you more hungry. So, I would just reframe, if maybe that you can try some other options. Oh, I also really like oil pulling every morning. Cynthia, that was long.

Cynthia Thurlow: Yeah. No, that was a very comprehensive response. I would just echo that. I understand that desire to have clean breath. I am not a coffee drinker and so, when I used to round on patients in the hospital, I would actually chew gum, but discreetly chew gum. No one knew I was chewing gum, because one of my biggest pet peeves are when people chew gum in a noticeable way, which I know is not the question. But I always tuck gum up into my gum. And so, I would chew it in between seeing patients. And during the pandemic, I stopped chewing gum, because obviously, I was home and there was no need to do it. And I realized, I actually didn't enjoy chewing gum. I just felt this compulsion. It became a compulsion when I was in the car or when I was seeing patients and so, what that has demonstrated for me and why I think this is relevant to Tracy is that what I really need to do is be hydrating more, because when your mouth is hydrated with water, that breath concern is not a concern, because sometimes dehydration will mitigate the feeling of having poor smelling breath and the other thing is, a lot of people drink copious amounts of coffee and so that can give them that kind of stale appearance. 

But the other thing that I would loop into what Melanie said is, Trina Felber is an advanced practice nurse and she has a company called Primal Life Organics. I've learned a lot about mouth care and the mouth microbiome. And so, I do tongue scraping every morning, I use her clean dental products, which don't disrupt the mouth microbiome and we'll link up that podcast I did with her, as well as a discount to Primal Life Organics. But I really do think looking closely at what you're eating, what you're drinking, and then also oral microbiome care can be hugely impactful. And I think for a lot of people, it's really just a habit. I do think that when you're chewing gum, your body thinks you're going to be eating food that you're actually going to swallow food. And so, do you get a cephalic phase insulin response potentially. Most of the gums that last a long time in terms of flavor have artificial flavors in them. They've got sucralose, they've got a lot of chunky things. Let's be clear, the gums that are clean don't last very long and that's from personal experience I can tell you. You definitely want to try to mitigate the net impact of some of those foods as much as you can. Then does it mean that you'll go from chewing gum all day long to not chewing gum? Probably not, but maybe integrating some of these other thoughts and I do like Melanie’s suggestion to rethink whether it's you're chewing on a fennel seed, or you're trying the WOW Drops, or using some essential oils, or you're drinking more water, those actually have some health benefits versus gum unfortunately has a lot of things about it that probably are not ideal to be doing all the time and it sounds like it's actually making you hungrier, which makes sense that your body thinks food is coming. 

The other thing that I just have to loop in here is that you're obviously a young woman still probably at peak childbearing age. Fasting for your menstrual cycle is really important. You may find that you struggle more on days when you're closer to getting your period and you really want to know that there are times in your cycle where it's ideally optimized to fast from the day you start bleeding up until ovulation. And then as you're getting closer to your menstrual cycle, the last five to seven days, you may want to back off on the fasting a little bit. And certainly, it sounds you've got a very tight window, a very narrow window. And the last piece that all add in here is, just making sure you're eating enough food. You were saying you're still trying to lose more weight and your body may think that you're not eating food, if you're not able to get two good-sized meals into a pretty tight window. So, those are my thoughts. I hope that's helpful.

Melanie Avalon: That was so helpful. You exactly articulated what I was trying to articulate, but you're much better, because you had the personal experience, which was, like, you're talking about how you really thought you needed it and then you realized it was a habit. It wasn't really about the gun per se, because it's interesting. Tracy was saying that the WOW Drops and the peppermint essential oil aren't the same. If the goal is addressing the clean breath, drops and the peppermint essential oil, they're going to have a very similar effect. So, it not being the same as probably that habitual aspect of wanting to chew the gum like Cynthia was experiencing. That was very powerful. Also, I forgot, do you do tongue scraping, Cynthia?

Cynthia Thurlow: I do. I do every day. Actually, it's become part of my morning ritual that my husband thinks is really funny and I'm like, "Oh, but look at all the stuff you pull off your tongue." [laughs] 

Melanie Avalon: It's game changer for me. 

Cynthia Thurlow: Mm-hmm. That's great for breath and everything else. I remember feeling paranoid when I was rounding. If I didn't have a mint or gum, it was because I had been conditioned. I probably walked around dehydrated all day long, because I didn't want to have to pee, God forbid. If you're dehydrated, you can get funky breath just from that. In many ways, I think the freedom of not chewing gum anymore is that I don't feel that way. It's like, "Oh, I'm feeling my breath is getting funky. I'm going to go drink some water." And then inevitably, I feel between that and tongue scraping and changing my dental products has really made a big impact in a positive way.

Melanie Avalon: Awesome. Definitely, report back Tracy, if you find something that works for you implementing all of this. So, awesome. 

Hi, friends. So, you guys know how seriously I take my health routine. That is probably the understatement of the year. One of my literal non-negotiables that I talk about all the time that I use every single day of my life is getting my daily dose of red light therapy. For years now, yes, years I've been using Joovv and I love it because it is so relaxing and so easy to use. You've probably heard me talk about Joovv before. That's J-O-O-V-V. I use my devices daily to support healthy cellular function, which is the literal foundation of our health. If you've heard any of my episodes on mitochondrial health, you know this is true. Having healthy cellular function helps give me peace of mind that my body is working efficiently and has the energy that it needs to get through the day. There are so many clinically proven benefits from red light therapy and I have personally experienced so many of them. I use the red light to naturally regulate my circadian rhythm. I wind down with it at night and wake up in the morning with it. Whenever I have any muscle pain or soreness, I shine my Joovv red light on it and the pain instantly goes away. It's actually shocking. I love it for skin health. It makes my skin glow. 

And you can also use it for things that I originally got into red light therapy for, which was supporting my thyroid. Yes, I struggle with hypothyroidism and supporting hair growth. Aside from the benefits, I've been recommending Joovv for years, because the quality of their devices is simply the best. Their modular design allows for a variety of setup options that gives you flexibility, plus the treatments are so easy and can be done in as little as 10 minutes, although, I tend to run mine all day as ambient light. All you have to do is relax and let your body take in the light. Joovv offers several different size options including a wireless handheld device called the Joovv Go. That is amazing for targeting specific areas around your body like hurting joints or sore muscles. When I traveled recently and had torn something in my knee, I brought my Joovv Go with me, game changer. I don't know how I would have survived the trip without it. The health doesn't have to be complicated and Joovv makes it simple by helping what matters most to our cells. So, go check out the Joovv today and while you're there, Joovv is offering all our listeners an exclusive discount on their first order. Just go to joovv.com/ifpodcast and apply the coupon code, IFPODCAST to your qualifying order. Again, that's JOOVV dot com forward slash IF podcast with the coupon code, IFPODCAST. Pick up a Joovv today, some exclusions do apply, and we will put all of this information in the show notes. All right, now, back to the show. 

Melanie Avalon: Shall we answer one more question? 

Cynthia Thurlow: Absolutely. This comes from Anna. The subject is: "fasting, electrolytes, and hot humid weather." Anna says, "Hi, ladies, I love the podcast. Definitely wouldn't have got through the first few months of one meal a day, 23:1 to 20:4 without it as it took me two months to become fat adapted. I've been doing one meal a day for two to three months and now that I'm fat adapted, it's become so easy and the scale hasn't moved much. I thought I'd try a 48-hour fast. I have the weight to lose 25 plus kilograms. I work outdoors in the hot, humid tropics, very sweaty. I drink around 7 to 10 liters of water a day around 2 gallons. I also clean fast. 48-hour fast was going so well. I was feeling completely fine and happy at work until around hour 43, I suddenly got blurry spots in my vision, felt extremely lightheaded, and really couldn't focus. I could hardly see or think. I'm wondering if this is just because I didn't supplement with electrolytes. I honestly thought a two-day fast should be fine and it felt so good until the eye floaters popped up. I felt normal the next day again after eating and sleeping. I am a healthy besides being overweight ha-ha young woman. I just wanted to write in because I think a lot of the info you guys give out is more suitable for indoor workers and more temperate climates than where I live. Thank you both so much for all your hard work on this podcast."

Cynthia Thurlow: Well, thank you, Anna for your question. I would say, first and foremost, there's a couple things that come to mind. I think if you're working in an outdoor environment where it's very hot and humid, you're doing a lot of sweating and you're not using electrolytes you're setting yourself up to become dehydrated very easily. I love that you clean fast. I think that's very important but electrolytes and fasting go together. It's not an either/or. In fact, I teach women all the time that you salt your food, use electrolytes and no it's not a couple sprinkles of salt in your water. You need a comprehensive product. And so, understanding the role of magnesium, and potassium, and chloride, and sodium is very, very important. We know that when you're in a fasted state, you're also going to upregulate excretion of sodium in your urine. Even though, you're consuming 2 gallons of water a day, you're not going to hold on to it. So, you will get dehydrated. 

You mentioned what sounds to me, you became symptomatic during a longer fast which I also wouldn't recommend, if you're in an outside environment and you're going a long period of time. A couple things for anyone who's fasting, especially if you're in a hot, humid environment, you're outside, water with electrolytes together throughout the day. There are plenty of clean products on the market. I think about unflavored LMNT, I think about Redmond's, I also have a product called Simply Hydration, that's also safe to take, it will not break a clean fast. And then if you're comfortable consuming stevia sweetened product, LMNT also makes a wonderful product with lots of flavors. My favorite is orange, obsessed with it. In my house, grapefruit is also a very popular option as well but I think if you're setting yourself up for longer fasts and you're not using electrolytes, that's a great concern. 

The other thing is, you're mentioning that you're in a position where you still want to lose more weight and I think that you probably need to have some varying amounts of time in which you're eating. You have a very compressed feeding window, you're not going to be able to get enough protein in a very compressed feeding window. I would recommend at least two meals in a feeding window. If you really like OMAD and that's your preference, then I would ensure that you are not over fasting because your body may be holding on to everything in an effort to-- because it perceives that you're not bringing on enough food in an unfed state. So, just some things to consider but I would say electrolytes are going to be your friend, you want to embrace them, find a product you like. 

And then the other thing is, I know Mel and I’ve both on several podcasts with Robb Wolf. We'll be happy to link up our podcasts with him but he provides some really compelling research and information that makes electrolyte utilization really important with fasting. And then lastly, I don't know how old you are but you want to make sure that you're not over fasting in a timeframe around when you'll get your menstrual cycle, because that can also make it quite challenging to fast effectively.

Melanie Avalon: That was so comprehensive and so helpful. 

Cynthia Thurlow: Thank you.

Melanie Avalon: Appropriately enough. LMNT is a sponsor on today's episode. You can actually go and listen to wherever we run that ad in this show. So, if you go to drinklmnt.com/ifpodcast, that's D-R-I-N-K-L-M-N-T dot com slash ifpodcast I believe the offer right now is eight single serving packets for free with any order. So, like Cynthia mentioned, the unflavored one is just epic and wonderful to be clean fast friendly and then depending on the context, they do have a lot of really amazing flavors. And word on the street. Have you made--? Oh, wait, you don't really drink. I know a lot of people make a margarita with the citrus salt one. Yeah, so, I think everything that Cynthia said, I echo. Those are really great suggestions. 

I did want to clarify because she was saying that the info that we give may be more suitable for indoor workers in more temperate climates. In general, the longer fasts, I think for anybody they shouldn't just be done casually. I think indoor or outdoor, there's definitely be attention paid to doing it correctly and paying attention to electrolytes. And definitely thank you, Anna, for drawing attention to that. Definitely, if you are in a situation like her, where you're in the elements and it's hot, and dehydration possibly being a factor, needing more water that definitely people should not take that lightly. I know we actually have had questions in the past about that and it definitely can make a big difference and not even just with longer fasts, but with shorter fasts as well. So, yeah, I'd be curious, Anna, if you try it again with electrolytes, let us know how it goes.

Cynthia Thurlow: Yeah, I think it goes without saying, I see a lot of people, men and women that fast and then wonder why they're dizzy, or they've got cramping, or they're new to fasting entirely, and they get "keto flu," and just explain the physiology of the body and how when we are eating a lower carbohydrate diet, and we get these renal losses of sodium, how that can mitigate and precipitate some of the side effects people will experience. And so, I'm not a believer in white knuckling it through fasting and certainly, electrolytes to me go together so beautifully with fasting. You just have to find a product that you like. For me, it's orange salt all the way during my feeding window and then my other product that I have that is not too salty. That's one of the things. Sometimes, people will say, the unflavored varieties are too salty. I totally get it. You just need to dilute it with more water and it'll be totally fine.

Melanie Avalon: Well, I'm so glad you said that, because yes, some people love it as is, but you really can dilute it and make it last longer. I've given one of my friends a lot of boxes of LMNT, and she loves it, and she just drinks them like candy. Some people just like it as is. Okay, awesome. Well, this has been absolutely wonderful. So, a few things for listeners before we go. If you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. You can follow us on Instagram. We are @ifpodcast, I am @melanieavalon, Cynthia is @cynthia_thurlow_. And the show notes for today's episode that will have a full transcript, as well as links to everything that we talked about will be at ifpodcast.com/episode287. All right, well, this was fun, Cynthia. I feel we haven't talked a lot recently, because it's been so crazy. So, it's been really nice to record today.

Cynthia Thurlow: Absolutely. And it just means for listeners, we're going to dive right in on our next recording. So, we'll get more questions fit into our discussion.

Melanie Avalon: Yeah. So, all right. Well, I will talk to you very soon. But for listeners, we will see you guys all next week. 

Cynthia Thurlow: Sounds good. 

Melanie Avalon: Bye. 

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and recomposed by Steve Saunders. See you next week.

[Transcription provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Oct 09

Episode 286: Thyroid Regulation, Iodine, Fasting For Your Cycle, Insulin, Glucagon, High Protein Diets, Surgical Menopause, Prescription Medication, And More!

Intermittent Fasting

Welcome to Episode 286 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

BUTCHERBOX: Grass-Fed Beef, Organic Chicken, Heritage Pork, Wild-Caught Seafood: Nutrient-Rich, Raised Sustainably The Way Nature Intended, And Shipped Straight To Your Door! For A Limited Time Go To Butcherbox.com/ifpodcast And Get A 10 oz New York strip steaks and 8 oz of lobster claw and knuckle meat FREE in your first order!

BEAUTY AND THE BROTH: Support Your Health With Delicious USDA Organic Beauty & The Broth Bone Broth! It's Shelf Stable With No Preservatives, And No Salt Added. Choose Grass Fed, Grass Finished Beef, Or Free Range, Antibiotic And Hormone-Free Chicken, or Their NEW Organic Vegan Mushroom Broth Concentrate! The Concentrated Packets Are 8x Stronger Than Any Cup Of Broth: Simply Reconstitute With 8 Ounces Of Hot Water. They’re Convenient To Take Anywhere On The Go, Especially Travel! Go To melanieavalon.com/broth To Get 15% Off Any Order With The Code MelanieAvalon!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get A 10 Oz New York Strip Steaks And 8 Oz Of Lobster Claw And Knuckle Meat FREE In Your First Order!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

The Melanie Avalon Biohacking Podcast Episode #12 - Elle Russ

Ep. 129 – Middle Age, Menopause, and Mindset: How These Components Affect Your Thyroid Health with Elle Russ

Ep. 105 Thyroid Physiology and Chronic Illness – with Dr. Eric Balcavage

Ep. 166 How to Maintain a Healthier Thyroid: Interesting Thyroid Physiology Health & Preventative Care with Dr. Eric Balcavage

The Melanie Avalon Biohacking Podcast Episode #1 - Dr. Alan Christianson

Ep. 154 How to Normalize Your Thyroid Function: What You Can Do To Help Support Your Body with Dr. Alan Christianson

Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist, And Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

Text "AVALONX" To 877-861-8318 For A One Time 20% Off Code for avalonx.us

BEAUTY AND THE BROTH: Go To melanieavalon.com/broth To Get 15% Off Any Order With The Code MelanieAvalon!

Listener Q&A: Ashley - Struggling with consistency

Listener Q&A: Monica - 3rd time is a charm?

High dietary protein intake, reducing or eliciting insulin resistance?

Effects of high-protein diet on glycemic control, insulin resistance and blood pressure in type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials

Protein: metabolism and effect on blood glucose levels

Ep. 109 How To Transform Your Health With Diet And Exercise – With Dr. Ted Naiman

The Melanie Avalon Podcast Episode # 30 William Shewfelt And Ted Naiman

The Melanie Avalon Biohacking Podcast Episode #94 - Marty Kendall

Listener Q&A: Jessica - Menopause, HRT, etc

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 286 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time, and get ready for the Intermittent Fasting Podcast.

Hi friends, I'm about to tell you how to get two grass-fed, grass-finished 10-ounce New York strips and one-half pound of sustainable wild-caught lobster meat all for free? Yes, for free. We are huge fans around here of a company called ButcherBox. They deliver 100% grass-fed, grass-finished beef, free-range organic chicken, heritage-breed pork, that's really hard to find, by the way, and wild-caught sustainable and responsible seafood shipped directly to your door. When you become a member, you're joining a community focused on doing what's better for everyone. That includes caring about the lives of animals, the livelihoods of farmers, treating our planet with respect and enjoying deliciously better meals together.

There is a lot of confusion out there when it comes to transparency regarding raising practices, what is actually in our food, how animals are being treated. I did so much research on ButcherBox, you can actually check out my blog post all about it at melanieavalon.com/butcherbox. But I am so grateful for all of the information that I learned about their company. All of their beef is 100% grass fed and grass finished. That's really hard to find. They work personally with all the farmers to truly support the regenerative agriculture system. I also did an interview with Robb Wolf on my show, The Melanie Avalon Biohacking Podcast, all about the massive importance of supporting regenerative agriculture for the sustainability of not only ourselves but the planet. This is so important to me. I'll put a link to that in the show notes.

The value is incredible, the average cost is actually less than $6 per meal. And it's so easy. Everything ships directly to your door. I am a huge steak lover. Every time I go to a restaurant, I usually order the steak. Oh, my goodness, the ButcherBox steaks are amazing. And we are so excited because ButcherBox has an incredible offer just for our audience. You can get some of those steaks for free and lobster to go with it. You can go to butcherbox.com/ifpodcast and get two 10-ounce, grass-fed, grass-finished, New York strips and one-half pound of wild caught sustainably raised lobster meat all for free in your first box. Yes, completely free. That's butcherbox.com/ifpodcast and we'll put all this information in the show notes.

And one more thing before we jump in. Are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense, because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting. It's actually our skincare and makeup.

As it turns out, Europe has banned over eight thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disruptors, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup maybe playing a role in that.

Beyond weight gain and weight loss, these compounds have very detrimental effects on our health, and they affect the health of our future generations. That's because ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years. Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means, when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves.

That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so, you can truly feel good about what you put on. And friends, these products really, really work. They are incredible, they have Countertime for anti-aging, Countermatch for normal skin, Countercontrol for acne and oily prone, and Counterstart for sensitive. I use their overnight resurfacing peel and vitamin C serum every single night of my life. And their makeup is amazing. Check on my Instagram to see what it looks like. Tina Fey even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more.

You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20, to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well.

And lastly, if you're thinking of making Clean Beauty and Safe Skincare, a part of your future, like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20, to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show.

Hi everybody and welcome, this is episode number 286, of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hey, Melanie, how are you?

Melanie Avalon: Good, how about you?

Cynthia Thurlow: We were just commiserating about this. But when your thyroid medication gets changed, it can sometimes be a little bit of a bumpy ride. So, I'm feeling I need to prop up my eyes with toothpicks today.

Melanie Avalon: I've been on the same bus that you've been on with trying all different forms of thyroid medication. It's just so complicated because there's so many opinions and there's so many options. And it can be hard to really find what works for you.

Cynthia Thurlow: Totally, I think if anyone that has an underactive thyroid that's listening, I know you understand [chuckles]. I know you understand, so I'm trying to just wait it out. My functional medicine doc is encouraging me to wait it out another week and get my labs checked. Goodness, I feel I need a power injection in the afternoon because I feel like I need a nap. And who has time for that every day?

Melanie Avalon: Well, I will say, this actually made me think about this. Sort of recently, I was in a period where I was feeling I needed a nap every day. And I just realized you know how you don't really notice when the negative things are gone? I just feel when I'm experiencing something negative once it actually goes away, I don't you may normally realize it. I just realized, "Oh, I haven't been needing a nap every day." I think the difference is, when I got sick a few weeks ago and started really high dosing the NMN and I stayed on the NMN every day at a higher dose. I don't need naps anymore. I think that's what it is, I don't know what else it would be. Although I have realized I feel a little bit more wired at night as well. So, I'm maybe I'm too high dosing. So, that's a benefit. I didn't used to be a nap person, and then I was and I'm not. How about you?

Cynthia Thurlow: Every once in a while, might need it but I generally, power through my day. And on a lot of levels, the fact that I consistently every single day, I'm this tired, the only variable that's changed is the thyroid medicine. And I knew this would happen because what typically happens is I get insomnia. And then, I have a crash in the afternoon. That has been a consistent pattern. Even though they've increased my T4, they lowered my T3. And my functional medicine doc said, and I quote, "You have the most interesting thyroid panel I've ever seen." And I said I don't want to be interesting I just want to be normal. I'm trusting the process. And he's absolutely brilliant and one of the smartest physicians I've ever met, so I am trusting in the process but in between, I will need naps in order to function.

Melanie Avalon: Do you think you'll increase your T3?

Cynthia Thurlow: He might. I think it's interesting, I'm supposed to have lab, he wanted labs drawn two weeks after I started the medication. So, I've already got that appointment set up, and I knew as soon as I started, I knew that there would be this bumpy-- this has been the pattern every single time they've changed my medications. In fact, I thought for a moment, because I keep all my old medicines just to describe to people, I'm not kidding, I really have been on 10 different prescriptions in the past two years. And it's a bag of thyroid medicine. And my husband was like, "What is that?" And I was like, "I don't know, it's a trophy. I'm keeping this for posterity's sake, I'm not sure." But to really demonstrate this is what people go through. And I'm a clinician and we still haven't gotten it right, so it goes on to just suggest that many people listening, are probably struggling with the same thing. So, that's why I wanted to share, to be transparent and say, "Yes, I'm a clinician. But yes, I'm still struggling to get the right combination of medications."

Melanie Avalon: I don't love that you're experiencing that. But [chuckles] I love it that's your approach. And yeah, some good resources for listeners. Have you interviewed Elle Russ?

Cynthia Thurlow: I have Elle and Eric Balcavage, Balcavage, sorry, I just mangled his last name, he's wonderful. He does a great Thyroid Thursday on Instagram. So does a lot of teaching. I think he's a great resource. And we both have had Alan Christenson on, but I would say Eric does a lot of didactic teaching as a clinician, which I love. And then Elle is all about empowerment, which is fantastic.

Melanie Avalon: Yeah. And Dr. Alan Christianson, who you just mentioned, it's funny, when I first met him, I was really struggling with my own thyroid panels. He is the nicest person ever because I literally just met him, and we've been vaguely emailing actually about intermittent fasting stuff. We were debating the literature on it. I guess at some point, my own thyroid issues came up and he was so nice. At one point, he was like, "Well, send me your labs to look at." I sent them to him, and he called me, he was like, "I have to talk to you about this [laughs] We have to get this fixed now." I was like, "Oh my goodness. You're the nicest person ever." He has a book called The Thyroid Reset Diet. He was actually my first episode of the The Melanie Avalon Biohacking Podcast.

Cynthia Thurlow: You what's funny, so fast facts. Alan was part of my Mastermind. When I joined it, and I recall the very first time I met him in person, I was sitting next to him at a lunch, and I was trying to be really cool. Because sometimes when you meet these people that you've been following them for years, and then you're socially around them. All I say to myself is, "Just be cool. He is a normal guy." And he is as nice as nice could be. I just think Midwesterners in general are just such nice, down to earth, human beings. And he really is as nice as he appears to be, and very quiet and introverted and I really enjoyed the time that I had with him, but I think he's a great resource.

Another funny thing to share with you is that the podcast team that I had at the time that I recorded a podcast with him about his new book about iodine, the podcast title was Intermittent Fasting and Thyroid Health, and I just about had a minor heart attack, because he's not a big fan of Intermittent Fasting. And I literally was like, "You cannot put that out. You cannot do that." And then, I had to explain the context. I was like, that is absolutely the worst title you could ever come up with.

Melanie Avalon: It's funny, the way I met him actually was-- I don't know if it was him or it was probably his publisher, or publicist, or somebody. They pitched him to come on this show. And it was for his metabolic reset diet. And literally at that time, he literally had a video on YouTube about-- it was basically deconstructing intermittent fasting. I wanted to engage with them. But Gin was not too excited about the idea. And so, that's why I started talking to him via email and started discussing the studies. And he actually took down that video, I think, after it because we talked about it some more and I think he realized there was a slightly more nuanced perspective on that specific content that he had created. And I just thought that was so impressive. But yeah, I know, I love his work. He has the thyroid reset diet, the adrenal reset diet. What's the book on iodine called?

Cynthia Thurlow: No.

Melanie Avalon: That's the thyroid reset diet.

Cynthia Thurlow: Yes.

Melanie Avalon: I'm still haunted by that. I still don't know what I think about it.

Cynthia Thurlow: I don't agree, politely I don't agree.

Melanie Avalon: I need to reread it, because it's interesting, because it's so contrary. It's not like it's slightly different than the popular idea. So basically, for listeners, a lot of people in the functional health world, and I guess nonfunctional as well, advocate needing more iodine to help thyroid and just health in general. And a majority of the book is about how iodine is actually the issue, and we actually need to be on a low-iodine diet. So, yeah, I don't know.

Cynthia Thurlow: I think it's important to entertain the possibility that there may be aspects to that argument that are applicable, but I don't necessarily agree but I don't have enough background, I'm not an iodine specialist, but I do ask my functional medicine friends and I would say iodine is a controversial issue because you have people like Brownstein, who is pro iodine, and wrote the book, The Iodine Crisis. And then, you have other doctors that feel differently. So, we have to agree to disagree. And I don't feel I know enough to feel I could take a stand on it. I'm in a state of flux.

Melanie Avalon: Reading his book, it's very convincing. And I do think there's probably a lot to maybe the difference between people who are eating a conventional diet, so they're getting iodized salt, compared to people who might not be having conventional salt, and so not having that source, I do wonder what role that plays. I do know iodine-- I know I've shared this on the show before I don't know if I've told you before. It's the only supplement that I experimented with that I had such obvious scary reaction that I was like, "I'm never taken this ever again." My eyes literally turned bloodshot red.

Cynthia Thurlow: Really?

Melanie Avalon: Yeah, that's kind of frightening [chuckles]. I remember I can't-- I can't even know if I can go to work. It was when I was still waiting tables. Yeah, so we will put links in the show notes. To the interviews we have had with all of these individuals.

One little announcement I do want to share with listeners, by the time this comes out, I feel bad because I think that this special will have already ended but the concept is still available, which is all the more reason you need to be on my email list for my AvalonX Supplements, which is avalonx.us/emaillist. And also, you can actually get text updates, and a 20% off one time code. I'm so excited, I set up text updates. If you text 'AvalonX' to 877-861-8318-- I'm just going to emphasize for clarity, Cynthia, have you ever set up a text service?

I have not. It's really funny because I say text 'AvalonX', all of the iterations I get of people texting that it's not AvalonX, people will text Avalons, or, give me the code or all these things. I'm like, "No, you have to text just the word AvalonX." So, it's a kind of like-- I don't know, it's just really funny to see all the messages. So, that's A-V-A-L-O-N-X to 877-861-8318. And if you are on that list, you would have known that we launched magnesium subscriptions. And we actually had a two-week window where you could get grandfathered in for life at a 25% discount, which is the largest discount we should technically probably ever do. And you get it for life as long as you stay on the subscription, which you can also pause. So, that's amazing, if you didn't snag the 25% you can still get a subscription now at 15%, so that's an option. Anything else from you, Cynthia?

Cynthia Thurlow: I am hopeful that we will finalize a package for the creatine so that I can get a date that this will be available. That is, I've got my fingers crossed.

Melanie Avalon: I'm very excited for you. Then someday, you'll have subscriptions on that as well, probably?

Cynthia Thurlow: Yes, you'll be able to tell me all about text options too.

Melanie Avalon: That's the thing I've learned, is be very clear in what people text to you.

Cynthia Thurlow: Keep it simple.

Melanie Avalon: It is simple, but people just extrapolate and text all the things and I'm like, "No, that is not what it says."

Cynthia Thurlow: It says not direct access to Melanie 24/7.

Melanie Avalon: Is not what it says.

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Shall we jump into everything for today?

Cynthia Thurlow: Absolutely.

Melanie Avalon: To start things off, we have a question from Ashley and the subject is "Struggling with consistency." And Ashley says, "Hi, I have been a fan and I've listened to your podcast from the start, which means I started IF back in April of 2017. I wish I could say I have done IF every single day since then. But no, it has been the struggle bus for me to do it consistently." Typically, since 2017, I IF on average four to five days a week. Some weeks are better than others when I can complete six to seven days of IF, where other weeks are harder one to two days. My window varies from 16 hours to 24 hours. Really at this point, I have been in maintenance, at times losing and gaining 5 pounds.

Now that I'm approaching my third year of IF, I've hit a roadblock in the mornings. I find myself so hungry. I usually close my window at 7pm the night before having dinner with my husband is very important to me, which is why I don't want to break my fast in the morning. It seems lately, I can only make it to 12 hours before caving on eating something some days. What I'm getting at is, do you all have tips or advice for getting through these humps? Have you ever experienced it before? I'm disappointed in myself with the inconsistency I've done with fasting over the past couple of years, which I know leads to not getting the best results. I do love the health benefits of IF and never regret it when I do fast for at least 16. It's just some days I find myself starving, and then I cave. Any recommendations you have, I would appreciate so much. Thank you."

Cynthia Thurlow: Well, Ashley, I don't know how old you are. So, I'm going to just keep this a broad response. When a woman is telling me she really struggles to get to 12, 13,14 hours, I think you need to look at your macros. Are you getting enough protein? Are the meals that you're consuming in that feeding window, are they sufficient enough calorically to be able to fill your body? Where are you on your menstrual cycle? We know the follicular phase from the day you start bleeding up until before ovulation is a time that you can get away with longer fast. And then as you transition to the luteal phase, as you're getting closer to when you're going to get your menstrual cycle, I generally recommend women fast no more than 12 or 13 hours. So, I don't know if you're in a premenstrual situation and the end stage of luteal phase and that's why you're struggling. I would really dig into if you're feeling you're a little bit weight loss resistant, how's your sleep? How are you managing your stress? Are you getting enough macros in? Are you over exercising? So, there's a lot of variables that aren't entirely clear. And I just start to see a lot of women that get into these situations where they start to feel they're not seeing the results. So, they restrict more, they're just not feeling their bodies. And I get concerned that your body may in response to not feeling it's getting enough food and is really pushing the envelope. And if you're that hungry, I would definitely recommend breaking your fast, but also understanding that there are things you can do that could potentiate your fast, but I just feel I need more information to be more specific than I already have been. How about you, Melanie?

Melanie Avalon: Yeah, I thought that was great. I love how comprehensive that there are so many potential factors going on. I would just add to it that I think a lot of people, when they're having issues with and this is what you're talking about, but a lot people when they have issues with finding the fasting hours that work for them, they think the answer is in the fasting hours, like adjusting when they're fasting. But I personally find that looking at the food intake side of things can often be potentially just as helpful or more helpful than that. Especially when people send in questions, because we have a pattern of people who send in questions.

Some people, when they're discussing fasting and their issues, they also paint a very clear picture what they're eating. Some people don't mention it at all, it doesn't even come up in the question like this one. And I don't know this is the case but that says to me that it's possible that there's not as much of a focus on what you're eating as there could be that would possibly really, really help. So, making sure that you're getting adequate protein in your eating window, which we have a question about protein coming up. And for some people, it's looking at the macros that you're eating can actually be super helpful for satiety levels. So, some people do better with the lower carb approach, and that's what really helps them tap into fat burning and not be hungry. Some people do better with a higher carb approach, and actually, those carbs are what keeps them satiated. So, I would definitely look at what you're eating, there's a lot of potential to find something there, in addition to all of the other amazing things that Cynthia brought up.

Cynthia Thurlow: Now, it's such a good point, I think we have to look at things comprehensively. When a strategy is not working, it's okay to take a break from fasting. That's the other thing that I don't hear enough people talking about, that there are times and cycles in our lives when fasting really does well for us and times when it does not and it's okay to take a break. If you feel your body's really communicating that it's not working, there are definitely ways around that.

Melanie Avalon: Yes, exactly. Especially tying into-- I was just looking at the part where she's talking about how it's some weeks that are good, and some weeks that are harder. And I really, really wonder, you were talking about with the menstrual cycle, if it does align that way. I think oftentimes people, with the menstrual cycle, they don't make the connection that there's that connection going on there.

Cynthia Thurlow: Yep. Absolutely.

Melanie Avalon: All righty. Shall we go into our next question?

Cynthia Thurlow: Absolutely, this question is from Monica. And the subject is "Third time's a charm." "I've listened to your whole podcast. I love all the information. It has seriously been so helpful in my fasting journey. Fasting has helped me overcome so much. Major hormone imbalances and an obsession over food that is totally mellowed out with the control I feel with fasting. It's wonderful and truly life changing. My question is something I never really thought could be an issue. But I found an article that said otherwise. Can a diet focused primarily around protein contribute to insulin resistance? I follow Dr. Ted Naiman who is a huge fan of protein over pretty much all else. But if you're constantly getting the spike in insulin from protein, could not have the same effect on our tolerance of insulin as sugar does. For example, a diet of low carb high protein low to moderate fat. I'd love to hear your thoughts and research. Love you guys. Seriously keep it up."

Melanie Avalon: Okay, Monica, thank you so much for your question. Really, I got so excited about researching this question, and I did a lot of research. So, I'm so excited to talk about this. So, yes, protein does release insulin. The difference between how it releases insulin compared to carbohydrates, for example, it varies. I was looking at a lot of different literature and there are charts on different foods and insulin release. And some charts will say, for example, that beef releases more insulin than carbs. But then, something else I was looking at was saying that protein requires about half of the insulin of carbs. So, it seems to be all over the place. But the point is, they both do release insulin in substantial amounts compared to fat, which is very, very minimal.

The difference with protein is it also releases a hormone called glucagon. And you can think of glucagon as the counter-regulatory hormones to insulin. So, insulin reduces blood sugar, puts sugar into storage. Glucagon actually spurs the liver to release glucose into the bloodstream. Let's say you're just eating protein, and you are nondiabetic, and you are good with your insulin regulation in general, in theory, you would eat some protein. And because you're not eating carbs with it, this is my example, the insulin would lower your blood sugar, actually, and then glucagon would actually encourage your liver to release glucose. And then, you just have a straight-line response, and you wouldn't really have those dips and swings.

All of that said, there can be some issues, potentially with, one, the fact that protein does release insulin. So, if we are eating a lot of protein constantly, we could be getting-- it could potentially encourage insulin resistance from all that insulin release, especially in the context of if you're eating a mixed diet, and you're also getting insulin released from carbs and things like that. And then, releasing the glucagon can actually also potentially be a problem, because now not only are we releasing insulin to store carbs that we might be eating with a meal, but we're also potentially releasing glucose from the liver, which might create a longer-term blood sugar insulin issue.

On top of that, the constant release of-- protein stimulates something called mTOR, which actually, it's a growth signal in the body. And there are studies on mTOR and insulin sensitivity, and too much stimulation of mTOR constantly, might also encourage insulin resistance. And then on top of that, there's a lot of studies on BCAAs. So, those are branched chain amino acids. They are some of the potential amino acids that we can get from protein. And studies are pretty consistent that high levels of those in the blood tend to correlate to insulin resistance. But the problem is, we don't know if it's chicken or egg. We don't know if high BCAAs in the blood cause insulin resistance. Or if when you are insulin resistant, your body is unable to properly get those BCAAs out of the blood. And the studies are very conflicting and inconclusive on the BCAAs.

I found a very amazing study that literally looks at this question that Monica had. It's from July 2014 and it's called, "High dietary protein intake, reducing or eliciting insulin resistance?" And it looked at all the studies to date. So again, it's a little bit older of a study, 2014. But it was looking at the studies to date that all looked at high protein intakes in different situations, and how did it affect insulin resistance and glucose control in the subjects. And I actually, because there's a lot-- It's a very long article. I actually went through and counted, because they didn't really give a graph. I just went through and counted what they actually found. I'm going to tell you because I find it very telling.

In studies of healthy people who are not obese, who are not losing weight, so this is a short-term, energy-balanced high protein diet. Basically, just going on a high protein diet for the short term, not calorie restricted, not losing weight. Three other studies found that when they compare that to a normal diet, there was no effect on insulin resistance, so we didn't see a negative effect there. And then, one study found a benefit, so that's favorable. The second category was people who are overweight also doing the same thing. Short term, they're eating a high protein diet, but they are not losing weight. One of the studies found that when they made the protein high diet with whey protein that there was a benefit. And when I say benefit, I'm talking about on insulin resistance. One study found that there was no change, so there wasn't any difference. One study found when they use casein and whey that there was no change. Another study was six weeks, it was high protein, and the protein was from legumes and whey, and they found that it actually-- the high protein decreased insulin sensitivity, but then it actually normalized the longer the people were on it. Another study in diabetics with that setup found that the high protein improved insulin sensitivity. The conclusion was that it's inconclusive.

Then, they looked at people who are on short-term diets where they were calorie restricted and high protein, and losing weight. And in those, well, they started off by saying that most weight loss diets leading to weight loss increase insulin resistance. So, if you're on a high protein diet and you lose weight, you're probably going to see a benefit in insulin sensitivity. But it's hard to know if it's from the protein or if it's from the weight loss. They found that two studies compared high protein diets to other calorie-restricted diets for weight loss and the high protein diets had more of a benefit. One study found, comparing it to a control, so not to a calorie-restricted diet, it found a benefit. One study found that the high protein diet did not have as beneficial of an effect on Homa IR, which is a good marker of insulin sensitivity, but it did have a better effect on beta cell function and the pancreas. So, that's a little bit confusing. And then, two studies found that it was the same benefit. And then, one study found that it was looking at high protein versus high carb in a calorie-restricted situation, and the high carb was superior.

Last category, I'm almost done. And then, the section looking at long-term intake of high protein diets, one study looked at six months of people who are healthy on high protein diets. And they found that those on the higher protein diets had higher insulin resistance and more glucose issues. A collection of observational studies on diabetes found that high protein diets led to more issues. But then The Nurses' Health Study looked at low carb high protein diets and they did not find those issues. And then they actually did find that long-term intake of high protein from vegetable protein actually benefited insulin resistance. And then, there was another meta-analysis that they referenced. And that looked at 15 randomized control trials of more than 12 months on the long-term effects of diets high in protein. And it showed neither a positive nor a negative effect on glycemic control compared to diet low in protein in both healthy and insulin-resistant subjects.

Okay, sorry that that was so much information. But basically, there's been a lot of studies looking at this issue. Like I just went through all of those, the effects seem to be pretty mixed. It's interesting, because the study I was referencing, they concluded that high-protein diets and insulin action are not univocal, which means unambiguous. So basically, it is ambiguous. And that insulin sensitivity seems to have a beneficial effect in high-protein diets when people are overweight or insulin resistant, and they are losing weight. In the short term, having a high protein diet doesn't seem to really affect insulin action. But in the long term, there might be a-- or they say it seems to be deleterious when the intake is prolonged. And that this goes along with seeing high plasma BCAA levels in the blood, like I was talking about. Their ultimate conclusion is that in the long term, increased insulin secretion and consequent hyperinsulinemia might lead to reduced hepatic insulin sensitivity. Increased hepatic glucose output results in a decrease glucose control, although a direct effect in insulin action and insulin sensitive tissues can also have a role.

My thoughts stepping away from all of this is that yes, if you are doing high protein-- well, especially if you're doing high protein in the context of energy-toxic diet, a diet with too much energy in the long term, I think definitely can encourage an issue, contribute to an issue. If you're eating protein constantly 24/7, it could have those issues with mTOR. It could have basically all of these issues. In the context of weight loss, I don't think most people would need to worry about this at all. In maintenance as well. I'm not sure but I do feel for people who are doing intermittent fasting, we're getting that period during the fast of low insulin. We're getting that period of low mTOR. I think it's crucial that we get adequate if not high protein when we do eat. So basically, I really think that the issue here is energy toxicity, not protein completely. That was a really long answer. Cynthia, do you have thoughts?

Cynthia Thurlow: No, I am in awe of the research that you did. My clinical context, just thinking thoughtfully about this question is, I'm 100% in agreement that the energy toxicity, meaning you're eating too much food, is really the issue. Now, when we look at the bulk of the population, we know 92-93% is metabolically inflexible and unhealthy, it is likely not too much protein, that's the issue. It's the overall there's just too much caloric or the macros are imbalanced. It's overwhelming the body's storage sites. And it is less about protein, and more about all of the other factors. Most people, perhaps not our listeners, but most individuals here in the United States are drinking caloric beverages all day long. They're eating anywhere from 6 to 10 times a day. And when you're really looking at the degree of meal frequency, the average American is doing-- average westernized person combined with those beverages, I think that is a greater issue. And for them, if they suddenly go high protein, and they still have all these other behaviors that I've identified, then that can become a larger issue.

And it's interesting, Ted Naiman, I've interviewed and I'm very aligned with him on many, many things. And he has this amazing book that is only an electronic book, which means I don't own it, because I like having physical books for most of my things that I want to reference. But he posts a lot of fantastic content on Twitter and YouTube. And it's a great resource. And he talks about how a certain amount of protein and fats will shut that satiety, you'll hit those satiety hormones that you just physically can't consume more food. And I think that's an important distinction along with everything else that you said. But I'm so grateful you did all that amazing research. I'm just going to speak to it as a clinician, and I think it has everything to do with an overconsumption of calories, in general, that is creating this toxicity and this degree of lack of metabolic flexibility and insulin resistance.

Melanie Avalon: Yeah, what you just said is basically exactly how I feel. And I think the nuance as well is that, so say we are in energy toxicity situation on a low protein diet, the energy toxicity is primarily coming from carbs and fat. Just stepping aside, in general, energy toxicity is, I think, the issue. If you have low protein, the factor that you don't have going on in that situation, is that you're not getting that glucagon stimulation, that would be prompting the liver to be constantly also releasing glucose from the liver, which would be further exacerbating issues as well as the potential buildup of those amino acids in the bloodstream. Compared to when you do have the protein, you've got that secondary issue going on.

And I did want to throw in, because I left out one other thing because that was 2014. There was actually a 2020 meta-analysis, and it looked at 12 articles with 13 studies including patients with diabetes, and they actually concluded that a high protein diet does not significantly improve glycemic control and blood pressure. They didn't say that it hurt it, they just said it doesn't improve it. But it can lower LDL, TC, TG and Homa IR levels in patients with type 2 diabetes. Further studies are needed to clarify the effects of high protein diet and glycemic control, insulin resistance and blood pressure control and type 2 diabetes. I just want to throw that one in there because I left it out.

But I'm glad you brought up Ted Naiman, I love him, we can put links to the episodes that we've had with him. I also really love Marty Kendall. He had a really good article on the glucagon aspect of this that I was reading, and he actually referenced Ted Naiman in that study as well. All that to say I agree with-- what you just said is what I agree with that. I think the issue is the energy toxicity.

Cynthia Thurlow: No, it definitely makes sense.

Melanie Avalon: Okay, I don't know if Monica expected that long of an answer. [Cynthia laughs] All right, we have a question from Jessica, and the subject is "Menopause, HRT, etc." Jessica says, "Hi, I love this podcast and I learned so much about IF. My doctor advised me to start IF a month ago when she put me on HRT. I'm 37 and still breastfeeding my daughter aged one, but I'm also postmenopausal as my ovaries were removed in December. My doctor advised HRT because my estrogen was unsurprisingly very low, and my DHEA and testosterone were very high. I've been doing IF starting at 16:8 a month ago, and now usually doing 18:6 and sometimes 20:4. I have not lost a single pound. My clothes do not fit differently. I am at my highest weight ever and getting so discouraged every time I step on the scale.

I have now been on low doses of bioidentical estrogen and progesterone for a month while doing IF. And although I feel some benefits, it's helped some digestive issues. I need the scale to move in order to feel my health is improving. Losing even a few pounds would give me hope, but it is just not happening. How long do I stick with this before it's time to admit it is not working for me? I'm also a vegetarian, but I sometimes eat the occasional fish. I'm reading that the research on IF for women is mixed, and it may have negative consequences for postmenopausal women. Is it possible this just isn’t for me? I hope that's not the case. Because this is the only diet, I've ever tried that I felt was sustainable. Thanks in advance, keep up the good work."

Cynthia Thurlow: Ah, Jessica, you have a lot going on. Oh, my goodness. You're still a very young woman, and we know women that have their ovaries removed before the age of 42 are at greater risk for developing cognitive issues. So, I'm grateful that your doctor is being very proactive and considering hormone replacement therapy. My concern is, and I'm just going to start from the top, I'm not in agreement with women breastfeeding or being pregnant and fasting. You're wanting to lose fat, but your body is still feeding a baby. And I'm sure if she's one, she's probably eating a lot of solids. And so, her breastfeeding might be brief and just a few times a day. But just something to think about in the position that you're in, you're giving your body mixed signals. You want it to lose fat, but you still want to be able to sustain being able to breastfeed, and I find for most women while they're breastfeeding, it's harder for them to lose body fat. So, that's number one. Since you're so young, I'm curious to know why your ovaries were removed at such a young age because that's very significant.

You're mentioning that your testosterone was high. The question is why. Did you have polycystic ovarian syndrome? When I start thinking about the reasons why women can have high testosterone, that's almost always the first thing I think about. Does your husband take supplemental testosterone? Probably not, because you're both very young, but you can sometimes get exogenous exposure that way. Just in thinking about the bioidentical hormones, it could be a combination of too much stress on the body, breastfeeding, fasting. Going into menopause is a big adjustment, and you have surgical menopause, meaning the average age of a woman in the United States to go through menopause is 51. You're 37. So, you're very, very young. And so, from my perspective, it's trying to get a sense from what you've shared as to what could be going on.

The other thing that I get concerned about is most vegetarians in my clinical experience consume too many carbohydrates, not enough protein. And you really have to work at that very diligently. If you're eating very limited, animal-based protein, hopefully, you're eating some eggs, which will make that easier. But the challenge is, if you're trying to fuel weight loss and you are vegetarian, you're very likely overconsuming carbohydrates. And then, you're also breastfeeding, and your body needs a little bit of extra fuel to be able to make that happen. I wrote a whole book about women and fasting.

And I generally will suggest the women check that out. There is research on postmenopausal women. And I find the women that generally do the best are the women who have stable hormones, meaning, when you're no longer menstruating, your hormone levels are stable, much more stable day to day, week to week than a woman who's still in peak fertile years, or even a perimenopausal woman-- there's a lot of good research that women can do very well in menopause, with intermittent fasting, provided that they're sleeping high quality sleep, they're managing their stress. And as a new mom, it's not unstressful to have a little baby at home and then stressing about trying to lose weight. I mean, those are two big things, eating anti-inflammatory nutrition, and really thinking about, things that fuel insulin sensitivity. And I think about walking after a meal, and lifting weights and things like that.

So, there's a lot to unpack here, I would give it more time. If you're breastfeeding, you need to give yourself some time. I used to always say six months was always that time period that I felt most of my patients got to a point where they were starting to see some weight loss, 12 to 18 months. And if you're still breastfeeding, it's going to make it a whole lot harder to lose weight. So, please give yourself some grace. Make sure you're getting your hormones tested, make sure you've got a DUTCH as well as serum blood labs. I think that would be very helpful. And the other question that dovetails into that is why is your testosterone so high? Did you have PCOS? What was the precipitant for removing your ovaries? That's a pretty drastic surgery for such a young woman. I would imagine there's a good reason, but just not a reason that's entirely clear to me right now. What do you think, Melanie?

Melanie Avalon: Well, I thought that was absolutely amazing and comprehensive. That was one of the takeaways I really took away from reading your book, Intermittent Fasting Transformation, was the difference with fasting in pre-menopausal and postmenopausal women and where do you think this idea-- because people ask this a lot or say this, that there are negative consequences for postmenopausal. But have you seen that? I mean, would the concern be I guess sarcopenia, not getting enough protein? I'm just wondering where this idea is coming from.

Cynthia Thurlow: I think there's a degree of fear mongering This is why I'm not a fan of OMAD. And that may upset people but I'm going to just say it, you just can't get your macros in. And once you're going through perimenopause, and menopause, physiologically, we are just much more at risk for muscle loss and the way that you need to think about how important and-- Gabrielle Lyon has been on your podcast, she has been on my podcast, she's a really close friend. I tell her all the time that her work completely changed everything that I talked about. But you want to think about muscles as a glucose reservoir. They're critically important for being metabolically healthy. And as you are losing muscle, and that's being replaced by fat--

I always talk about the filet, which is young muscle. Melanie has young muscle Melanie, so Melanie is a big fillet. And I'm 51, so my muscles, if I don't work really hard, are going to look like a ribeye and a ribeye is delicious. But we want to be a filet for as long as we can be. And I'm not talking about aesthetics. I'm talking about musculature, it's so important. And the concern I get is when postmenopausal women, perimenopausal women are just bucking this trend of, "I'm only hungry for one meal a day and that's all I eat," I just have to remind them, one of the reasons why you're not more-hungry, is you're starting to lose lean muscle mass. And as Gabrielle says, "You are not overfed, you're undermuscled." So, it's really important to understand that I think a lot of the concerns and fear about menopausal women is largely a byproduct of this concern that they are going to lose muscle mass if they're not eating at least two meals a day, we're not talking about 6 meals a day, or 10 meals a day, which I eat two meals a day so that you can get enough protein in your diet.

The other thing that I think is important note is that we're de facto less tolerant of stress as we head into perimenopause and menopause. It's a byproduct of the loss of progesterone from our ovaries, as our adrenals are stepping in to help support our body, we are just not as stress resilient. That doesn't mean we can't manage stress, we don't manage it as well. And so, I think on a lot of levels, there's this concern that if women head into their 40s, and 50s and beyond, and they're overfasting, overrestricting, not exercising or doing the wrong types of exercise, that they can put themselves at risk for a lot of inflammation, a lot of bodily stress. But I sometimes feel menopausal women have an easier time because they don't have to deal with the factors of a menstrual cycle and follicular phase and luteal phase. I would say men and menopausal women can sometimes have the easiest time fasting of all because they don't have to worry about this biology of procreation and conception and fertility and infertility that younger women have to worry about. But I do think it's a huge problem.

In fact, I'm not going to say this person's name, but there's a person who just had a book come out and they love to fearmonger about women and fasting. And I've had to have this discussion quite a bit. And I don't want anyone to perceive that. If you're sleeping well and you're dialing in on your nutrition and you're managing your stress and you're fasting for your cycle and you're not overexercising, that fasting can't be a part of or eating less often, can't be part of your strategies that you use to feel good about navigating whatever stage of life you're in. I think a lot of that comes from well-meaning people who don't really know what's going on. That's my feeling.

Melanie Avalon: I cannot agree more. It's actually similar or relates to the findings speaking of what you're talking about earlier with protein, on protein and longevity. There are so many people, researchers and such like Dr. Valter Longo, who I've had on the show-- he's actually been on this show, and he's been on the biohacking podcast, but he and people in his sphere are very much pro low protein for longevity up until, I think, age 60. And then, you need higher protein. So, I think that does relate to everything Cynthia was talking about, about when you are at that older age and the more difficulty it is to create and maintain muscle, women in particular really need the higher protein when they're older. I don't think that should be lumped in with the fasting, which I think can happen. It just might be like Cynthia was saying that you need a longer window to get in that adequate protein intake if you're not like me where I eat all the protein.

Cynthia Thurlow: The unicorn, but I think that's one of the reasons why I love podcasting with you as we really speak to such a wide age range of women. And I think that's really important because if we were both 50 somethings or if we're both 30 somethings, we would not necessarily totally represent our demographic, right?

Melanie Avalon: Yeah, exactly. It's funny before I even started the show, way back, I remember brainstorming about what did I want the show to look like. And at first, I was like "Oh, I want to cohost with somebody like my age. And it'll be two girls having wine night, two young people." But when I met Jen, I was "Oh, this is actually much more appropriate," because it's just so much helpful to give the broad perspective, and then it's even better when we're friends as well. It's all the good things.

Cynthia Thurlow: Exactly. And I think it's important for people to understand that there's a genuine camaraderie here. So, we can both benefit from our own experiences. My kids know who Melanie is. When we talk about Melanie's eating window, and her sleeping habits and how different we both are, and that's the beauty of it is that there's listeners who very likely-- there might be someone who has a long, evening eating window and stays up really late-- And I think, it's only when I was traveling in Europe that we overlapped at the same time, like we were awake for the longest stretch of time at the same time. I was like, "This is cool."

Melanie Avalon: Yeah. It's funny, I get DMs from people because I do think my approach is very rare. But there are? I know you guys are out there who actually do it very similar to me, and quite a few people DM me, and they're just like, "Thank you for letting me know I'm not alone in my crazy late night, feast every night." So, we are out there, but it definitely doesn't work for everybody, that is for sure.

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All right. Shall we answer one more question?

Cynthia Thurlow: Absolutely. This is Mary, "Prescription meds breaking fast." "Hello, I've just begun IF." So, her eating is either 19:5 for two days or 20:4. "I've long abstained from between meal eating, so this was a fairly easy transition for me. I am determined to have clean fast. However, I saw a comment today on Facebook regarding melatonin, and the word was that it does contain sugar, so realistically breaks the fast. I have a long list of prescription meds. So far, I've looked at four that are must-haves, and they all have that same ingredient. My feeding window is 12:30 to 4:30. I can take my evening pills right at 4:30 and some of my AM pills right at 12:30. But some must be taken 12 hours apart. My question is, if I take the must-haves when I wake up, does that wreck my clean fast? Eager to hear. I want to do this right. Thank you for your time, Mary."

Melanie Avalon: All right, Mary, thank you so much for your question. So, something to clarify, because I can see how this can happen. You talked about how you heard melatonin, and it contains sugar, and so, it breaks the fast. And maybe this goes without saying but with something like melatonin, which is not a prescription, there are many brands of melatonin, and they do not all contain sugar. So, melatonin does not equal sugar, does not require sugar to be taken. For melatonin, for example, you can find a melatonin that is fast friendly. We love melatonin from MD Logic for example. So definitely check them out. You can use the codes, MELANIEAVALON or CYNTHIA, to get a discount on that I know Cynthia in particular has really benefited from that melatonin. So that's supplements like non-prescriptive supplements, you can usually find a version that is clean, fast friendly, especially when it's not a prescription because there's normally lots of versions of it.

When it comes to prescription medications, if you have to be taking your prescription medications, you have to be taking your prescription medications. Some of them might contain ingredients that break the fast like she has found out. I'd be curious what she found in it that was-- I'm wondering what the sugar ingredient that she's thinking. I'm wondering if it's something-- I'm just wondering what it is exactly. There are a few things. One, I think a lot of people don't realize this, but this is actually an option. You can actually get a lot of prescription medications compounded, I actually do. If you have a compounding pharmacy that you like and can work with, they can often make compounded versions of your medication with the exact fillers that you want, or even no fillers. It's not always a possibility. And sometimes if it's a possibility, it's extremely expensive, so then it's not really a possibility. But for some of the medications, it is a possibility. I've done that in the past for things.

If that's not the case and you need to go with the traditional prescription form, there are a lot of generic versions of a lot of prescription medications. You can look up the prescription and you can try to find the one that is the most "fast friendly." It does take a little bit of detective work, I'm thinking of little detective emoji in my head. But that is an option. And you can talk with your doctor if you want a specific generic version prescribed. All of that said, if you need to take the prescription medication and you cannot find a clean, fast friendly and you cannot get it compounded. It's okay, [chuckles] you have to take your medications when you have to take them. It's not like this is actual food. I'm not giving a greenlight to taking in minute amounts of sugar or anything that in general. But when it comes to medication, you have to take your medication. Don't stress about it. It will be very minimal, if anything. Those are my thoughts on medication. Cynthia?

Cynthia Thurlow: The irony is I have 45 cohort going right now, and we had our first group call. And that was the first question that I was asked today. And here's the thing, if you have to take a medication, you have to take a medication, period. There should be no stress about, does it break your fast, does it not breaks your fast? I'm always very transparent talk about the fact I take now compounded thyroid medicine, and I take that during my fasting window and that does not break my fast. Now, the issue with generics, and people may not know this, but you can get these tremendous variances. There are generics you can get sometimes like 20% variants. As an example, before I was taking compounded progesterone, I would sometimes wonder why some nights I'd sleep really well and some nights I wouldn't. My functional med doc actually pointed out, "Well, you realize, you probably remember this but for generic medications, even though it's a bioidentical, you still have this variance." And so, I would just state that-- sometimes the trade medications that you pay a little more for-- and by no means am I telling people to break their budget to do this, but if you feel you don't do as well on a generic, just understand it can be 20% different than the trade product. I had a lot of women, especially my thyroid patients, that would tell me they would not take generic Synthroid. They only took regular Synthroid because they had intolerances. I had patients on antihypertensive, so medications for their blood pressure, same thing. We're all individuals but please do not let the concern about breaking a clean fast be the reason why you perceive that you have to do all these different things to me make this work.

Now, there should be no sugar in melatonin. And if there is, then I would definitely look for another option. I speak very openly that the two options I use are Sandman, that's a whole other special conversation about that supplement. But the MD Logic melatonin is more efficacious, meaning it's stronger than the Designs for Health product I'd been using for several years, and I even used on myself as well as my patients. One capsule of MD logic was equivalent to three of the Designs for Health sustained release. To give you an idea, it's very cost effective, and I'm not sharing that to sell everyone on that brand, but just to share that's what works for me. Sandman is a per rectal melatonin, but it's also largely cost prohibitive for the average person, I probably use it twice a month. But with that being said, please don't let that be a concern. Now, if your supplement has sugar in it-- there was a woman in my other group who had a product that had 40 grams of sugar and 30 grams of carbs. And I was like, "First of all, you need to throw that in the garbage."

Melanie Avalon: In what? Supplement?

Cynthia Thurlow: Yeah, there were gummies. And I said, "Okay, well, a gummy is going to be full of sugar, because it's going to be soft and--" Anyway, a whole separate conversation. But the point of what I'm sharing is, we want to try to find the cleanest options that are out there. Things without gluten and dairy and grains and soy, just be diligent when you're selecting supplements to try to find really high-quality products. Yeah, that's my ramp. But please don't let concerns about your medication breaking your fast keep you from taking medications that you are prescribed and that you need.

Melanie Avalon: That's so fascinating. I know you said you've seen it in hypertensive medications as well. Do you find it is more the hormonal supplements where that's an issue or is it just across the board?

Cynthia Thurlow: Well, it's interesting, because many years ago, when I was taking oral contraceptives, I remember when I was a student at Hopkins, I had this one brand of oral contraceptives. And I also had mild phenotype PCOS, I had no idea why I had these crazy wild periods. Well, it's because I had PCOS and that's why I initially went on the pill. And the student health center was "Oh, we've got the generic version of what you're taking." I went on the generic and gained 10 pounds. And I remember them saying, "Oh, there's nothing different in this." And then, I remember talking to my faculty, and they were like generic is exactly that. They only have to have 80% of the formulation the same.

Melanie Avalon: Legally?

Cynthia Thurlow: Yeah, and you can have different fillers. There's lots of things that happen with these medications that I used to say-- Some people do fine with the generics, let me be clear, there's nothing wrong with generics. But I think there are definitely people who are much more sensitive to additional fillers and different formulations of medications. And so, that's where I think it's important to just have the conversation. If you're doing fine on what you're taking, great. If you're not, investigate what other options are available.

Melanie Avalon: Wow. It's interesting, because I had sort of vaguely wondered that in general about the generics, but I hadn't really looked into it.

Cynthia Thurlow: Yeah, up to 20%.

Melanie Avalon: Um, it's concerning.

Cynthia Thurlow: Yeah.

Melanie Avalon: Well, thank you. That's very valuable information. Thank you for sharing.

Cynthia Thurlow: You're welcome. It'd be a little depressing for everyone to hear. But the irony is one of my pharmacist friends and one of my doctor friends just happened to say that to me the other day, and I was like "Oh, my gosh, I forgot that. It's so true. It makes complete sense."

Melanie Avalon: Wow, wow, wow. Well, thank you.

Cynthia Thurlow: You're welcome.

Melanie Avalon: For listeners, if you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. The show notes for today's episode, which are going to have a lot of links, as well as a full transcript, will be @ifpodcast.com/episode286. And then, you can get all the stuff that we like at ifpodcast.com/stuffwelike. And you can follow us on Instagram. We are @ifpodcast. I am @melanieavalon, and Cynthia is @cynthia_thurlow_. All right. Well, this has been absolutely wonderful. And I will talk to you next week.

Cynthia Thurlow: It sounds good.

Melanie Avalon: Bye.

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman. Editing by Podcast Doctors. Show notes and artwork by Brianna Joyner. Transcripts by SpeechDocs. And original theme composed by Leland Cox and recomposed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Oct 02

Episode 285: The Mandela Effect, Dry Fasting, Nutritional Supplementation, Pregnancy, Prenatal Health, Maintenance Fasting, Intuitive Eating, And More!

Intermittent Fasting

Welcome to Episode 285 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

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SHOW NOTES

LMNT: For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase! Learn All About Electrolytes In Episode 237 - Our Interview With Robb Wolf!

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Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

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AVALONX MAGNESIUM 8: Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist, And Use The Code Melanieavalon For 10% On Any Order At avalonx.us And mdlogichealth.com!

Listener Q&A: Leah - Ship food and I don't mean cruise liner

Enjoy 20% Off at At Energybits.com With The Coupon Code MelanieAvalon or CYNTHIAthurlow!

Ep. 226 The Ultimate Superfoods: Spirulina and Algae with Dr. Catharine Arnston

The Melanie Avalon Biohacking Podcast Episode #129 - Catharine Arnston

Get an exclusive discount at melanieavalon.com/perfectamino with the code melanieavalon!

Listener Q&A: Jacek - Fasting without water

Dry Fasting Physiology: Responses to Hypovolemia and Hypertonicity

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Listener Q&A: Sara - Fasting and pregnancy

Athletic Greens: Get A FREE 1 year supply of immune-supporting Vitamin D AND 5 FREE travel packs with your first purchase at athleticgreens.com/IFPODCAST.

Listener Q&A: Rebekah - 16 Hour Daily Fasts Enough for Weight Maintenance?

Listener Q&A: Heidi - Learning your body

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 285 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time, and get ready for The Intermittent Fasting Podcast.

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And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense, because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting. It's actually our skincare and makeup.

As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disruptors, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup maybe playing a role in that.

Beyond weight gain and weight loss, these compounds have very detrimental effects on our health, and they affect the health of our future generations. That's because, ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years. Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves.

That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin so you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They have Countertime for anti-aging, Countermatch for normal skin, Countercontrol for acne and oily prone, and Counterstart for sensitive. I use their overnight resurfacing peel and vitamin C serum every single night of my life. And their makeup is amazing. Check on my Instagram to see what it looks like. Tina Fey even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more.

You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20, to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well.

And lastly, if you're thinking of making clean beauty and safe skincare a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20, to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show.

Hi everybody and welcome. This is episode number 285 of the Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hey, Melanie.

Melanie Avalon: Cynthia, I have an important question for you.

Cynthia Thurlow: Okay.

Melanie Avalon: When you had your boys growing up, did they watch VHS Disney movies? Or is that more of a girl thing?

Cynthia Thurlow: Did they watch Disney movies? Yes.

Melanie Avalon: There's a reason I'm asking.

Cynthia Thurlow: Yeah. So, DVDs, yes. And that was before like streaming was a thing.

Melanie Avalon: So, were they growing up at all during the VHS phase?

Cynthia Thurlow: No. Unh-uh.

Melanie Avalon: Okay, so this might not be applicable. My sister and I [chuckles] had like a two-hour conversation about-- have you heard about the Tinkerbell Mandela Effect?

Cynthia Thurlow: No.

Melanie Avalon: Okay, this is not even relevant. Well, I will [chuckles] put it out to the audience, because I posted about this on Instagram. And I don't think I've ever received so many DMs in my life about something. So, are you familiar with the Mandela Effect?

Cynthia Thurlow: Not offhand.

Melanie Avalon: Oh, it's so fascinating. It's basically the concept of memories that society will have that are not real. It started from this idea where apparently-- you would know this. Do you have a memory of Nelson Mandela dying in prison in the 1980s?

Cynthia Thurlow: I thought Mandela died in the 2000s because I was actually in South Africa when he was still-- let me see, what year did he die?

Melanie Avalon: 2013.

Cynthia Thurlow: Yeah.

Melanie Avalon: Okay, so you are not part of that. So apparently, a lot of people remember him dying in the 1980s.

Cynthia Thurlow: No, because I was going to say when I was actually in Cape Town. I was in South Africa when he was still alive.

Melanie Avalon: Okay. Wow. Yeah. So, that's where the name came from. But there's all of these examples. So, if you google Mandela Effect and there's a Wikipedia page about it. There's all these things where people have memories that are just not accurate. And it's a lot of like weird things where it's like why would everybody remember this very specific thing? That's not true. It's a lot of like logos like people think the Fruit of the Loom has a cornucopia logo, but there's not people think with a Chick-fil-A that it's spelled, how do you think Chick-fil-A spelled?

Cynthia Thurlow: Isn't it? It's like CHIK?

Melanie Avalon:  Right? That's what people think it's not. It's CHICK.

Cynthia Thurlow: See, you know what's interesting though like to me in my brain there's a difference between knowing when Mandela died. Versus like fast-food names. But I agree with you, I can see that.

Melanie Avalon: I remember in the VHS's, of Disney movies with the opening icon where it's the castle, I remember some sort of thing where Tinkerbell comes and flies and like dots the 'I' or like touches the castle with her wand. And if you go online and my sister remembers if you go online, there are like Reddit threads and boards like hundreds of comments and YouTube videos with people being like, "This happened. I remember it," but it didn't. Nobody can find any footage of it. And when I posted it on my Instagram, I probably got 40 DMs of people being like, "Yeah, that happened. I have it in my VHS's." And I had to respond to everyone and be like, "Well, if you find it, you're going to go viral, because nobody can find it." Isn't that crazy?

Cynthia Thurlow: That's just crazy.

Melanie Avalon: So, I don't know. It is a rabbit hole. So, listeners, if you remember this, and if you have footage, please let me know. Because you'll change the internet. Sorry, that's my random opening.

Cynthia Thurlow: No, no, I was going to say, were we spending time last evening thinking about this contemplating?

Melanie Avalon: No, I just had it on my to do list to bring it up on the show, because I literally went down the rabbit hole sort of recently. And then with the Instagram I was like I have to talk about on the podcast. I want to hear our listeners' thoughts, because we have an audience of 40,000 people, and I want to be vindicated in this memory.

Cynthia Thurlow: [laughs] But it's so funny that when you said Mandela died in the 90s, I was like "No, he didn't." I was there. Like I wasn't there when he died but I was in Cape Town the year that he passed away. So, that left an indelible impression on me. And if any listeners have ever been to South Africa or Cape Town, it's one of the most beautiful cities I've ever been to.

Melanie Avalon: It's just so fascinating. Some of the other ones are people apparently remember some Sinbad Genie movie that does not exist and--

Cynthia Thurlow: Are you talking about the really bad, like 1960s version that has very obvious faux creatures.

Melanie Avalon: Is it with Sinbad?

Cynthia Thurlow: Yeah. But no, not the Sinbad. Like the comedian in the Sinbad story.

Melanie Avalon: Oh, oh, no, this is the comedian.

Cynthia Thurlow: Oh, yeah, no, mm-hmm.

Melanie Avalon: And then like, where's Waldo?, people remember him incorrectly. There's so many things. I find it so fascinating. Oh, Froot Loops is the way it's spelled. It's F-R-O-O-T, Froot Loops.

Cynthia Thurlow: Is it really?

Melanie Avalon: Mm-hmm

Cynthia Thurlow: My parents never let me have those cereals.

Melanie Avalon: I need to ask my mother this, because we could eat the conventional cereals. Like all of them but we couldn't eat Fruity Pebbles because it "had too much sugar." And I have no idea. Like, didn't they all have too much sugar? Why was Fruity Pebbles different? Yes.

Cynthia Thurlow: No, my mom is first generation, and she was very strict about what we ate. Not per se in a bad way but it was a very nutrient-dense whole food. Like we were eating fresh, made bread and liver before it was in vogue.

Melanie Avalon: Wow, I'm jealous of you.

Cynthia Thurlow: No, I don't like liver. To this day, I don't like-- I think it's too metallic. I'm never going to be that person that can eat organ meats and do it with a smile on my face. I'm just being honest.

Melanie Avalon: I've thought about this a lot. I've talked about it with things. I would think that I would like organ meats because of the way I eat and they're so nutritious, but I just don't. They don't taste good to me.

Cynthia Thurlow: Yeah, it's very metallic. I remember and I know you've interviewed Paul Saladino on your podcast as well. And one of the listener questions was what is he eating, and he had just had like spleen and pancreas. And I think I vomited in my mouth. I was like, "Wow."

Melanie Avalon: Testicle?

Cynthia Thurlow:  Yeah, I was like, "That's so impressive." And I'm so impressed. But I could not do that. Not willingly.

Melanie Avalon: It reminds me of the guy who runs Ancestral Supplements who's on Instagram, he's always eating all the organ meats. And Joe Rogan recently made a comment about him being on steroids or something. And he responded and he's like, "No, it's all the organ meats."

Cynthia Thurlow: Oh, jeez. [chuckles]. More power to you, my friend.

Melanie Avalon: Yeah, well, in any case, anything new in your life?

Cynthia Thurlow: No, just three programs are like underway. September's always like a super busy month. And I'm just grateful. And hopefully my creatine will have a date for it to be officially launched. I'm just kind of holding my breath. Lots of little things along the way that we've had to dial in on to make sure it's perfect to be able to share with the world.

Melanie Avalon: I'm so excited for you for that and I'm so excited to start taking because I've never taken creatine.

Cynthia Thurlow: The one thing that's interesting is if you read the research on creatine, that's number one. I mean, there's real research, but I've been taking it consistently, since I-- so, when I had my hip surgery in May, and then I wasn't clear to go back to the gym until June, and I didn't get back to the gym until like late June, early July. I track all of my progress through an app on how much weight I can lift and I'm consistently going up by 10 or 15 pounds every single week. And that's with consistent utilization of creatine, which I'm excited about.

Melanie Avalon: Do you know if a person-- because I eat such a high protein diet, do you think I would still benefit from creatine supplementation?

Cynthia Thurlow: I think you could, and I've had conversations with Dr. Gabrielle Lyon about this because obviously I've had her input on some recommendations. We know if you look at research that menstruating women, so if you're actually actively menstruating, menopausal women, vegetarians, and vegans actually need more creatine than those that are not actively menstruating, those that are not postmenopausal. In terms of the research, I think most would do well with at least 3 grams a day of creatine. And then if you're one of those people, like vegetarian, vegan, because you just don't get enough exogenous creatine in your diet, they would likely need 5 grams a day. So, definitely there's differentiators for individuals. And you're still at an age where you've got peak bone and muscle mass. Very different than if you're looking at a 40-year-old woman versus a 50 or a woman versus a 60-year-old woman. So, I think that you're at a position to be able to really maximize muscle mass at your age, knowing what you know, versus people that are a little bit older. They have to work a bit more diligently to build that muscle.

Although it's interesting, one of the things that I've learned is, as we get older, our protein needs actually increased because we don't pull as much-- I mean we just don't break down the amino acids quite as effectively. And so, a 30-year-old like yourself, I know you eat copious amounts of protein, your body probably does a better, more efficient job breaking the protein into amino acids and assimilating them than someone at my stage where I might have to eat a little more protein to make up for the fact that my body doesn't utilize it as efficiently. And that's something I'm constantly thinking about. That's why it's so important you're hitting those protein macros, as opposed to things we just take for granted. Our bodies just don't work as efficiently as we get older. It's almost like we become a very fine-tuned car. And so, there's less bandwidth with which to work with and you have to really be consistent to be able to see efforts. I look at my teenagers who put on muscle effortlessly, because their bodies are in this massive anabolic phase, versus where I am where I'm in more of a catabolic phase, unless I'm working against that diligently. I'm not sure, did that help?

Melanie Avalon: It sounds like, especially as you're older, it's much more of a needs-based situation compared to maybe from just more of an optimization situation.

Cynthia Thurlow: Absolutely. And that's the beauty of being younger/.Things just work at a more optimal level. And of course, we don't realize this until we get older than we're like, "Oh, I never appreciated that because I just didn't know." That's kind of how I reflect on the differences of what I knew 15 years ago, versus now like, "Dang, had I known I would have lifted really, really heavy in my 20s and 30s." And whereas now it's like it requires twice as much effort to get enough of that muscle protein synthesis, and a little bit of HRT definitely helps.

Melanie Avalon: Or it's kind of similar to-- the next supplement I'm making with the NMN, very similar. And that I feel like when you're older, we know NAD levels are so depleted with age. And so, you would definitely from a needs space be wanting to take it and in higher quantities compared to when you're younger, it just helps. It just optimizes everything. Obviously. We're curious, in general, with that, with creatine, with anything, I wonder what the effects are. If you do start younger, and doing it consistently, are you kind of warding off some of those deficit issues later?

Cynthia Thurlow: I would hope so. I've had whole conversations with my kids about the fact that-- one's almost 18 years, he's fully grown, He's 6 feet tall. And whether or not we're going to consider adding creatine, that remains to be seen. I think when you're a fully grown adult, it's different than people who are still kind of growing in this massive anabolic phase, especially young men.

Melanie Avalon: Yeah, completely makes sense. Wow, super excited for that to be available. So, listeners, stay tuned. When it is available? You think it will be on your website?

Cynthia Thurlow: I think that's the general plan. We're going to actually create a lead page so that people can get on the list for when it goes on sale, because we do anticipate it will sell out and so they'll get the first rights of purchase over other individuals.

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All right. Shall we jump into everything for today?

Cynthia Thurlow: Absolutely.

Melanie Avalon: All right. So. to start things off, we have a question from Leah. And the subject is "Ship food, and I don't mean cruise liner." Leah says, "Good morning, Cynthia and Melanie. I'm a Navy sailor and so is my fiancé, Chris, who is actually on deployment right now. He is totally on board with IF. Ha, ha." I think your pun is funny, Leah. "And he tried to start it while he was out on the ship but it's difficult because meals have set times when the galleys are open, and the food is definitely not choice food. Knowing that IF is here to stay for me even if when I should wind up back on the ship, and that he very much wants to get into shape and stay that way, so IF we'll probably stick around for him too, I have questions about supplementation in the absence of being able to make better food choices.

For those of us who don't have the ability to get food that is good for our bodies, is there something we could use to give our bodies the nutrients needed? Examples would be anything fresh in the way of fruits and veggies. For my last deployment. I remember it being difficult to find spinach and the salad bar was often quite sad and fruit was really, really rare. Everything was ultra-processed, and the breads were all the cheapest white breads. Rice too was low quality. Now that Cynthia is on the show as a resource from the healthcare field, and knowing that Melanie is all about the food choices, I wonder if either of you all would have ideas on how to be as healthy as possible without access to wholefoods or farmers' markets, or such things as I've started to utilize after learning about food industry things. God bless your tangents, Melanie. That led to your other show.

I fully intend to utilize some of the supplements I've already experimented with while looking for foods that had the things, like iron in the form of beef organ supplements and Melanie's magnesium that I also got my mom onto." Yay. "And try others as I go along. But my knowledge of supplements is limited to what I've learned from y'all. There's also powders for greens and things, but I don't know how to sift through them. Ha, ha, you can tell I love dad jokes and puns and learn which ones are good and which ones are not worth it. Basically, assume I'll get some form of meat, pork and chicken and occasionally ground beef, limited to one or two servings per meal. And that's about it. Everything else will need to be something I provide myself. This is daunting. Sorry, y'all, Leah."

Cynthia Thurlow: Well, Leah, thank you to you and Chris for all that you do to help protect us as a nation and for Chris' current deployment. When I read through your question, I thought immediately of Athletic Greens, which is a product that I myself have used over the last two years. And for full transparency, I think I've tried everything on the market, and I'm not exaggerating. And I find most greens powders are incredibly herbaceous, to the point where they're not palatable. Athletic Greens has been something that myself, my husband, and my kids have been able to utilize. And I think it's a really nice balanced way to get quite a bit of vitamins, minerals, and greens powders into your diet, especially if you're feeling or perceiving that when you are deployed, you're really limited in your fresh fruit and vegetable options alongside with protein. So, I probably would make one investment as opposed to multiple investments and at least try it out. I think that's a good first step in order to kind of flesh out the options that you have available. And plus, it's convenient, because they have little packets that you can just throw into water. So, you don't have to a blender, you can literally throw out one of their shaker bottles and use some filtered water and you've got a really clean option that you can utilize. It's high in ORACs, so high in antioxidants. And it tastes good, which is most important because if it tastes good, then you'll consume it.

Melanie Avalon: Awesome. Yeah, speaking to the Athletic Greens, personally, I have actually haven't tried them or used them, but I knew Cynthia was a huge fan. And they approached us about wanting to support the podcast, which is awesome. And I was like, "Oh, I know Cynthia loves them." So, we will have a code for them. Because I know they're on your other show as well. In general, Cynthia, do they normally have a discount code? Because we don't know right now, as of this recording, what our offer is going to be. Is it normally a discount?

Cynthia Thurlow: Typically, what they do is they give you a free vitamin D and then travel packs. That's part of using the discount code. So, it's really convenient, because for me, I don't like to have to put things in plastic baggies to take them with me. I can just throw the travel packs in my luggage or my bag and it's totally portable. And who doesn't need more vitamin D? Let's be honest.

Melanie Avalon: Awesome. So, by the time this episode does air, there will be a spot for it, an ad for it in this episode. So, either look in the show notes and/or listen to that when it plays in probably a few minutes, and it will have the offer. So, check out that link for the offer for that. I would supplement that, no pun intended, I'm a little bit unclear if she can just bring supplements, or if she can also bring packaged food type situations. Because basically the way I would approach this is maximizing-- I know you said you're limited on how many servings of meat that you can have, but maximizing all of the servings of meat that you can get. The nice thing about meat, and this is something that Robb Wolf talks about a lot, which is that even the worst quality meat-- and I know there's lots of issues with conventional agriculture. And I could go on a whole tangent about that and problems with it and how it's not humane and the environment. And I'm not just saying that that's not a problem. That said, conventional meat is still very nutritious, which is great for protein, vitamins.

So, I would maximize all of the meat that you actually can eat. If you can bring actual packaged food with you, some things you could bring would be-- I don't know what stores are called in different places. But like at Kroger and Ralph's and places like that, you can get salmon pouches that are in these-- I don't remember what the brand is. They're like packets and they're salmon and the good thing is, they don't say wild caught on the-- or they might. I have read that canned salmon and packaged salmon tend to be wild caught actually. So, I would get like those packets, those would be really easily transportable. Other protein sources like jerky sticks and things like that. I know. Isn't there a brand that you'd like for jerky, Cynthia?

Cynthia Thurlow: I love Paleovalley, I'm devoted to Paleovalley. I love Paleovalley. We'll include a link in the show notes. That's my favorite by far.

Melanie Avalon: Okay, awesome. So that would be an option as well. Then also, if you feel like you're just not going to get enough protein, this might be a situation where you want to bring a protein powder. I've had on my shows, both John Jaquish as well as Dr. David Minkoff. They both have a protein powder supplement that's a complete protein powder without additives. Dr. Minkoff's is called Perfect Amino. I'll put a code in the show notes for that. So, for that, you can go to melanieavalon.com/perfectamino and use the coupon code, MELANIEAVALON. So, that might be something to try.

And then, moving beyond the actual protein, the second aspect of it would be what Cynthia was talking about with Athletic Greens. Getting those greens-related nutrition, and then some. I do think the Athletic Greens would be an amazing way to go. Something else might be spirulina tablets. We're actually currently in development to create a Spirulina that I will have produced, in part, which will be very exciting. So, stay tuned for that. In the meantime, I love, and listeners have really loved Catharine Arnston's ENERGYbits.

Cynthia Thurlow: She's awesome.

Melanie Avalon: Yeah. I really like those listeners really love those. And those are really, really rich nutrition. Do you have a code for them as well, Cynthia?

Cynthia Thurlow: I do. I literally just had a podcast drop about a week and a half ago from her. So, we can include that.

Melanie Avalon: Yeah, I know, mine for that is energybits.com with the coupon code, MELANIEAVALON, for 20% off.

Cynthia Thurlow: And mine's CYNTHIATHURLOW.

Melanie Avalon: Perfect. So, either of those will get you 20% off. And then like I said, we are hopefully developing my own. But I think that algae situation is a really great way to get really concentrated nutrition in a very travel global form. Another thing to consider might be nutritional yeast, if that's something that you like. Well, first of all, I find it so delicious, but it is just like super high and all of the vitamins including B12. So, it can be great for vegetarians and vegans, which I know does not apply to you but that's another great option. Although I personally really advocate getting a version without folic acid because a lot of them are fortified with folic acid. There's one brand I really like called Sari, S-A-R-I, so I'll put a link to that in the show notes. But that's all the things I would look into.

Cynthia Thurlow: I think that's very comprehensive.

Melanie Avalon: Awesome. Well, hopefully that was helpful for Leah. Shall we go on to our next question?

Cynthia Thurlow: Absolutely. This is a question from Jasick. The subject is "Fasting without water." "Could there be some health benefits to prolonged not drinking anything? I mean, not even water? Do you know of anyone who's seriously considered that or is it just assumed that there are none? Seems to me, all the evolutionary arguments usually given in favor of fasting apply just as well also in that case."

Melanie Avalon: All right, Jasick. Thank you so much for your question. I'm actually very surprised by the lack of scientific literature looking at this, I thought there would be a lot more studies and there are all I could find like as far as large studies go, I found a 2020 study called "Dry fasting physiology responses to hypovolemia and hypertonicity." And then, I found one called Effects of daytime dry fasting on hydration, glucose metabolism and circadian phase. A prospective exploratory cohort study." And do you know if it's Baha'i, is that how you say it, Cynthia? B-A-A-H-A-I with a lot of interesting punctuation, symbols. Something in India, I believe Baha'i fasting. So, in those volunteers, and that was a 2021 study- It was nice reading the studies. They also noted in the study that there's not a lot of literature, which not that I like reading that, but it makes me feel better about not completely missing something when they're saying that, "Yes, indeed, this is not very much explored."

So, the 2020 study was a very small study, but they basically looked at five consecutive days of dry fasting, that's a long fast, preceded by two days before where they ate normally, and then three days after where they ate normally. And they were just basically looking at their biomarkers and were trying to see if it had any negative effects on everything that they were experiencing. And they concluded that it was essentially safe to follow and there wasn't anything too concerning.

And then, the follow-up study was the one that talked about in those Baha'i fasting people. And what it was noting was that a lot of the studies on fasting are typically on people fasting for Ramadan, and that this Baha'i fasting situation was actually a more appropriate way to look at dry fasting specifically. And they as well found that it's safe and has no negative effects on hydration, it can improve fat metabolism and it can cause transient phase shifts of circadian rhythms. The improved fat metabolism is something that I think people talk about, because you will hear about people dry fasting, and it's come up in a few different books that I've read.

And it is advocated, and I say this hesitantly because this is what "they say, but like I said, I couldn't find many studies on it. They say that you will burn more fat if you're dry fasting. And the concept, or at least one of the theories is that when you're not taking in water, your body needs hydration. And so, we can actually create metabolic water by breaking down fat. And it's actually something that's not in the context of dry fasting and weight loss but Dr. Rick Johnson, who Cynthia and I both love, he actually talks about this whole process of metabolic water created from fat.

And so that study that I referenced in the Baha'i people who are fasting, they did find when they compare the data to Ramadan fasters, that it seemed like-- they said basically, in Ramadan, with weight loss, it can be all over the place. Like sometimes people lose, sometimes they don't. In this Baha'i study, everybody seemed to lose. And they posited that potentially dry fasting could lead to more weight loss than not dry fasting. So, yes, my takeaway, it sounds like when it's studied scientifically, that it's probably okay and safe from a health perspective. That said, I can totally see that people might have issues with electrolytes. So, please don't go by just that. If you're going to dry fast, go by your body and how you feel. It's possible that you might lose more weight dry fasting than not. We definitely need a lot more research on all of it. Do you have thoughts, Cynthia?

Cynthia Thurlow: I do. And it's interesting, because the conversation that I had with Rick Johnson when we talked about the camel, everyone assumes the camel has water in its hump and it's actually fat. And so that metabolic water that's created as the camel needs food was fascinating, and I think in many ways, really shifted my thought process about dry fasting. Now with that being said, I think dry fasting is absolutely positively a more advanced technique. This is not for newbies; this is for people who are very attuned to their bodies. I think that dry fasting is something that's employed by a lot of influencers that are out there. And I think you have to be very mindful of your own baseline health before you start utilizing it. If you're someone that's prone to orthostatic dizziness, you're dizzy, you get lightheaded, probably not the strategy for you because part of dry fasting is not ingesting any water. And there's hard dry fasting and there's soft dry fasting, let me explain a distinction.

Melanie Avalon: Did not know about that.

Cynthia Thurlow: Oh, yeah, it's fascinating. So, I've been down a rabbit hole about dry fasting. So, soft dry fasting means you still take a shower. Because you're still absorbing water, when you are showering, right? If you are a hard dry faster, it means you are not bathing. Or maybe you're quickly washing your armpits and other areas that need washing. But you're really not getting in a shower, you're not getting in a bath, you're not absorbing water through your skin. You're very, very devoted to the process of a hard dry fast, which is designed to be exactly that, hard. It's my understanding that a lot of people were so conditioned to being hydrated during the day, I know I'm very water focused all day long, which is why, more often than not, if I do a long podcast, I have to run the bathroom when I'm done just to empty my bladder.

But with that being said, I think this is absolutely a strategy that we probably need more research on. It's not one to be entertained by people that are new to fasting. That's my personal opinion, I think it's a strategy that should only be utilized by people who are ready for that kind of fasting, because it is going to be a bit more vigorous than a traditional water fast for 24 hours or a water fast or 48 hours. And you really have to understand that you may lose weight during the dry fast. But as soon as you hydrate, that's probably going to just kind of equal out. I think it's being very clear about what are you trying to do. A lot of people are like, "Oh, I want to do dry fasting, because I want to lose more fat." And that's all fine and good. But I think for me personally, although I have tried dry fasting, I'm the kind of person who really enjoys drinking water. So, it's actually harder for me not to drink water than it is for me not to eat food because it's such a part of my lifestyle.

I think there's a lot that remains to be seen. I would imagine a lot of the big intermittent fasting community probably would be aligned with what we're saying that we need more research. This is a more advanced technique. In fact, I'm in the midst of creating like an advanced intermittent fasting, either webinar or series or class or something, and dry fasting will absolutely positively be part of that.

Melanie Avalon: I wish they would do some randomized controlled trials, and really trying to figure out if this theory about dry fasting, creating the need for water, and so breaking down fat to create metabolic water that we otherwise wouldn't have broken down, I would just love to know if that's actually what's happening. Because if so, it's potentially a very nice tool in the toolbox to do smartly. But it would be nice to know if that's actually the case [chuckles]. Or if it's just people are not drinking water and so all the weight loss is more related to dehydrated cells. I'll be excited to see what you continue to learn with all that, especially if you do integrate it into some of your programs.

Cynthia Thurlow: Yeah, definitely, it's on the to do list. And every week, my team and I have a meeting and every week, we say. "Cynthia is going to table this till next week." I was like, "That's right."

Melanie Avalon: It's one of those things.

Cynthia Thurlow: Yeah, It's like I have a long list of things I want to do when I can't get all the things done in my life. So, it'll happen eventually.

Melanie Avalon: So, my assistant for the biohacking shows emails me every Wednesday with an updated list of guests we are reaching out to and where I'm at with certain guests. And there's some people that I just table every week. I'm like, "Ask me next week [chuckles] Ask me next week." But it's always on the list.

Cynthia Thurlow: Yeah, I mean, there's the things that have to get done. And then, there's a long list of things that should get done.

Melanie Avalon: Awesome. Shall we go on to our next question?

Cynthia Thurlow: Absolutely.

Melanie Avalon: So, the next question comes from Sarah. Subject is "Fasting and pregnancy." And Sara says, "Hey, gals, you've covered bits and pieces of this question on other podcasts, but I'd love to hear what you imagine would be a good beginning to protocol to follow once one discovers she is pregnant. I'm not currently with child, but if I was, for instance, do you IMMEDIATELY stop fasting when you get pregnant, when is it okay to start fasting? Again? I know fasting while nursing is a no, no, but when is it okay to resume? How do you resume a more typical all-day eating schedule? Do you talk to your doctor at all about fasting? Inquiring minds want to know. Very best, Sara."

Cynthia Thurlow: Well, Sara and this is definitely an area that I talk about in my book and certainly across social media. I feel very strongly that when you are creating a human or feeding human, it is not the time to restrict your macro intake. If you found out at six weeks that you were pregnant, I would stop that, and this would be my best recommendation. Of course, I would discuss this with your physician, OBGYN, etc. My general recommendation would be when you find out that you're pregnant, you stopped fasting. You're in a position where you're growing a human and especially at the key areas of neurodevelopment, you don't want to be restricting healthy fats, protein, etc.

And from my perspective, when you're done breastfeeding, I think it's absolutely fine to resume intermittent fasting. I know that I have never had a larger appetite than I did when I was breastfeeding. I have two boys. I breastfed both of them for a year. And I jokingly say I could eat like a linebacker. I have never been able to eat that much food since then. But I cannot fathom-- and this is not judgmental. I'm just saying I cannot fathom how you could get by with fasting and breastfeeding because I ate copio-- I mean, I probably had three or four meals a day, large meals, and I was still hungry. And that was not even with exercising. I just walked when I was breastfeeding, I didn't even go to the gym and lift.

I think from that perspective, stopping when you find out you're pregnant with fasting, resuming fasting only after you're done breastfeeding, and having a conversation with your healthcare professional. I've spoken to many, many, many physicians and researchers about this. And we're 100% in agreement about how important it is not to be fasting while pregnant, and not to be fasting while breastfeeding.

Melanie Avalon: So, at that moment, when they find out they're pregnant, and they immediately stopped fasting, do you have a recommendation for how they resume that all-day eating schedule?

Cynthia Thurlow: I think just having like a 12-- like having three meals and maybe having a 12-hour eating window, I think is absolutely fine. I don't encourage anyone to stuff themselves. But when you're actively growing a fetus, the idea of being restrictive about behavior is one that's woefully unaligned with fetal development and neurobiology and all the things that I know. And certainly, I'm not a researcher. But in conversations with so many experts, I feel very, very comfortable saying I would not recommend fasting. I think a 12-hour digestive rest kind of formulation. Same thing I tell women, five to seven days preceding their menstrual cycle, if they back off on the fasting and just have a 12-hour eating window, I find a lot of women actually do really well with that. And 12-hours should really be the minimum for all of us whether we're fasting or not. There should just be 12 hours of digestive rest. It's a great way to optimize digestion.

For a lot of women in pregnancy, they start struggling with constipation, they have a lot of reflux. Especially as the fetus is growing and it's putting more pressure on their digestive organs, it can make eating more challenging because they just can't eat large boluses of food. So, they may find that they have to eat a little more frequently, not in a negative way, but they may find that they tolerate maybe a slightly smaller meal and maybe they're eating every four to six hours in that window.

I had two boys that are 26 months apart. I had an 18-month-old when I got pregnant with my second son. And I remember I was one of those people that when I breastfed, I was working part time as an NP and my options in the hospital were either to have time to pump or eat. So, for the first year of my older son's life, I pumped in the hospital while I was running on patients, and I really didn't have time to sit down and eat a proper meal. So, I ate whatever I could grab on the go. And I'm not suggesting women do this, but it was either I ate a protein bar or I ate nothing. And so, I ate a lot of protein bars on the days I worked. And by the time I got pregnant with my second son, I had no adipose tissue, I was very skinny. I don't recommend anyone do this. But I didn't even realize it was so subtle, I had really lost all my fat stores because they were being utilized to create breast milk. So, I recall my first-- and I was underweight for where I normally was. In the first trimester with my second, I want to say I gained 10 pounds. And my OB wasn't worried because he knew. He just said, "I think your body had to get back to a certain level of body fat to be able to sustain a pregnancy." And I just kind of mindfully ate. I remember there were certain things I craved but I didn't crave junk. It was mostly like protein and carbohydrates, and that's really what my body craved.

I think each pregnancy is unique and different. I was surprised at how good and active I was throughout my pregnancies. I know not everyone may be in the same position, but I was pleasantly surprised.

Melanie Avalon: Do you know if there's a concern about if a woman is breastfeeding and losing weight of the toxins from the fat stores going into the breast milk?

Cynthia Thurlow: I mean, that could be. I mean, that certainly could be a possibility. I think that this is why we want our health really optimized before we become pregnant. I think a great deal about the fact that I have one child who has life-threatening food allergies, so it weighs heavily on me. Was there something I did that made him more susceptible to developing food allergies? I think every mother blames themselves. There's something I must have done that created this, even if empirically there's no evidence to suggest otherwise.

But I think if a woman is already obese, and she gets pregnant and she's potentially releasing some of these toxins, whether it's heavy metals or estrogen-mimicking chemicals, etc., absolutely, I think about-- and I don't have current research on this. So, I can't speak to it beyond just thinking in my knowledge about what happens through lipolysis. I do think that would be of concern if someone was unhealthy and became pregnant. And it also speaks to the fact that people who are metabolically unhealthy are more at risk for certain pregnancy complications, gestational diabetes. Certainly, women that already have PCOS, as an example, are at greater risk for complications related to a multiplicity of factors.

I think the big takeaway from me is, get as healthy as possible before you become pregnant. I know sometimes that occurs randomly, and sometimes people don't have-- the planning per se is maybe not in place but it's certainly something- and that's why I think prenatal nutrition is important. Prenatal care is important. I think it's important to be thoughtful about if you're choosing to have a child that your health is really optimized. Before becoming pregnant, I'm in some ways, I'm grateful, I didn't know as much as I know, now, back then. Because there's a lot that I think about. But from a de facto clinical perspective, absolutely. Everything is intertwined. And we used to think about adipose tissue as just being its own organ, but we didn't think about how sophisticated it was, we didn't know. And now, we understand it's highly inflammatory, full of cytokines, all sorts of inflammatory matter that you don't want to have released into breast milk ideally. But having said that, certainly people have survived through the millennia without knowing as much as they do now.

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Melanie Avalon: All right, shall we answer another question?

Cynthia Thurlow: This is a question from Rebecca. Subject is "16-hour daily fast enough for weight maintenance." "Over the course of the past two years, I lost 100 pounds through Weight Watchers. I found that I enjoyed eating bigger meals. So, a lot of times I ran out of points by 2 PM and unintentionally fasted intermittently in order to make Weight Watchers work for me. A coworker asked if I ever looked into intermittent fasting since I was already doing it many days per week without realizing it. Now that I've already reached my goal weight, I started tracking my fast with a goal of 16:8. Most of the time when you two recommend smaller windows to listeners, it seems to be for weight loss. Since I already have my portions under control and have been maintaining my weight for seven months so far, I wanted to ask how important is it that I try to increase my length of daily fast.

I think what I'm asking is it okay if I just enjoy my life on 16:8 since I feel great and I'm at a healthy BMI. I feel the pressure to only eat one meal per day since you both follow this plan, but I'm resisting the idea. Asking your permission to stay where I am. Thank you for your podcasts and your books. I bought both of them." And I just want to note that this question actually came in while Gin was still hosting.

Melanie Avalon: Yes, the comment about only eating one meal a day was the protocol that Gin and I follow, although we debate the terminology of what constitutes one meal a day. So, I actually could answer all of this just in one word, which is yes. It's okay. You have permission, Rebecca. But the longer answer is-- I find it really interesting. I feel probably Rebecca and I think a lot of people might experience this, especially in the dieting world. It's safe and comfortable to exist within a specific plan. So, Weight Watchers was a really regimented system and it worked for you which is great and congratulations on losing 100 pounds, that's incredible. So, that probably felt very safe. And while existing in that, you were doing what the system told you to do, and it worked. And so now, you're at a weight that you love and at BMI and you feel great, but you're not quite doing the system that has been attributed-- although historically, I hope we haven't given this impression that you can only lose weight on one meal a day, because that's not at all the impression I would want to give. So hopefully, we can clear up that confusion. But there's probably this idea that sticking to that protocol, instead, will-- again, it brings that safety as the thing that you should be doing to have the weight loss.

But there's all of this theory and conjecture and what people can say will work. And then, there's what's actually working. And what you're doing right now is working. So, 100%, you are totally fine to be living your life on 16:8 and having that for maintenance. You don't need permission, you can grant yourself permission for anything you want to grant yourself permission for. I'm all about listening to your own body. So please don't feel the stress. Of reason that you might want to do a longer fast, I wouldn't even say for the maintenance of the weight loss. It might just be a therapeutic longer fast. So, maybe you want to get some of the health benefits of increased autophagy, and just a longer fasting from that perspective. So that's the reason I would do a longer fast if you wanted, but I wouldn't for the maintenance. Thoughts, Cynthia?

Cynthia Thurlow: No, I think that was a beautiful explanation. Congratulations, Becca, on your sustained weight loss, that's incredible. I come at this from a similar/different perspective. I think that a lot of what is important for sustainability in terms of weight loss is getting sufficient amounts of protein in and that's much easier to do in two meals a day. So, if that's working for you, I think you should experiment if you want to do an 18-hour fast, a 16-hour fast, a 14-hour fast, you want to do a 20-hour fast, I think one thing that I think is very important is that we not get into a widget where we only do the same thing every day. We don't eat the same foods every day. We don't do the same exercise every day. I think it's important that we honor and nourish our bodies with some degree of flexibility. And one of the ways that you can do that is just to play around with your fasting window. And if you don't feel like doing a longer fast, there's no pressure to do so. I think that being very clear about what your goals are, what's important to you, you're not looking to lose weight. And there's a lot of research to demonstrate this kind of law of diminishing returns. If you're already at a healthy weight, doing a prolonged fast, finding where exactly that middle ground is, in terms of how much benefit are you getting from 24 hours of fasting or 48 hours of fasting, if you're not looking to lose weight, you can end up losing muscle. Muscle is pretty important for women. I don't know of your age, that's another piece of the puzzle. But I think you're doing a beautiful job. And I would just encourage you to experiment to find what works best for you and your lifestyle.

Melanie Avalon: Yeah, I thought that was great. And we actually have another question that sort of relates to all of this from Heidi. Would you like to read that, Cynthia?

Cynthia Thurlow: Absolutely. Subject is "Learning your body." "Hi there. I've been off and on for intermittent fasting for a year or so. For some reason, I keep giving myself reasons to stop. Anyway, I've been listening to your podcasts and reinforcing what I know about the process. My question is, I keep hearing you mention to listen to your body, and it will tell you what to do. Keep fasting, eat what you want to eat, etc. How do you learn to know what you're listening for? How do you become more in tune with what your body needs? I can get through about a 62-hour fast and feel pretty good, but not sure how to determine what my body needs after that. Any suggestions are welcome. Thank you in advance, Heidi."

Melanie Avalon: All right, Heidi. This is a great question, and it ties really well into what we were just talking about, especially because I think it provides a little bit more nuance and complexity to what we were just saying about potentially switching things up or listening to your body and making those decisions. Because I think on the flip side, so while we want to support everything that we just said, I think people can also get into a space where maybe having some sort of paradigm to exist in that does have more delineated-- I don't want to use the word 'rules', but does have some sort of parameters, I think can be very, very helpful. Because on the flip side of listening to your body and living intuitively, some people can do really well with that, and they really will just fast as long as they need to fast and eat when they need to eat. Some people won't. Some people need some sort of guidance. And it sounds like for you, you've been doing IF on and off, but then you don't stick to it you give yourself reasons to stop but then you also do like a 62-hour fast which is very long. So, clearly you are able to fast. There just seems to be some sort of-- I don't know if it's like cognitive dissonance or just inability to find a protocol that is something to stick to while still being intuitive.

What I would suggest, and I hope that doesn't undo everything that we were just saying, is if you want IF to be a part of your life, I would subscribe to a daily fasting window that maybe has flexibility in the parameters, but it would still be a daily fasting window. So, rather than fasting, and then not fasting, and then doing a 62-hour fast and being confused about what to do, and then worried about what to eat, maybe deciding to, "I'm going to fast daily," maybe around like 16:8, and then having some sort of flexibility surrounding that. So, maybe fast, a little bit more one day, a little bit less one day, but I would find something that you can stick to that actually can provide some consistency. And then, within that consistency, being more flexible if your goal is that you want to have IF as a daily part of your life. I wanted to talk about this with everything that you were saying, Cynthia, is I think it can be hard for people because we can say, "Be intuitive and listen to your body," but it's kind of like what Heidi says, what does that actually mean? And I think some people actually do benefit from picking some sort of system and then being more flexible within that system.

Cynthia Thurlow: I couldn't agree with you more. And one thing that I think is important for listeners to understand, we can talk about bodily intuition and intuitive eating, intuitive fasting, but if you're not metabolically healthy, which is most people, most people are, I think it's 92% to 93% of people are not metabolically healthy, you have to get those hormones balanced first. And I agree with you 100% that you need some type of a system to work within before you're going to be ready to intuitively fast, eat, etc. I think we do a lot of disservice when we expect people who are not metabolically healthy to be able to intuitively lean into what their body's telling them because there's this lack of insulin sensitivity, there's profound food cravings that go on, they're not sleeping well, they've got stress management issues, there's so much to unpack there.

And I say this with love. This comes from the most loving place in the world. But if you're feeling you're struggling with the concept of intuitively doing anything, it's because your body's not in a place yet where it's ready to do that work. So, until that point, I would have systems in place. And it doesn't have to be complicated. It could be as simple as, "I'm going to check my blood sugar after I eat a meal. If I'm still feeling hungry, and my blood sugar is high, then it might be that I had too many carbohydrates. It could be that I need to ratchet down on a portion of something that's going to mitigate and improve some of those symptoms."

We could have a whole episode just talking about these things. But I think it's important for people to understand that those processes and those symptoms take time to lay down. I think even for those of us that are metabolically healthy, I'm always changing things up. I'm usually transparent after the fact is I kind of work through carbohydrate tolerances, exercise, etc. So, I think we always have to invite ourselves to change things, to not feel like we have to be rigid and dogmatic. And I think dogmatism is a huge problem. Whether it pertains to a particular nutritional dogma or fasting in general, sometimes people don't realize that they're so rigid that they're no longer serving their primary needs of why they're embracing a particular philosophy or strategy.

Melanie Avalon: That was so perfect. That was exactly what I was trying to say [laughs]. It's very rare that I hear something-- well, probably shouldn't say it's rare. It is rare that I hear something within the type of content that I tend to consume, where I think it's a concept that could be doing a lot of damage. And I think there's a lot of potential damage that happens with messaging surrounding intuitive eating. Like I was listening to one podcast, and they were basically saying that you should be able to eat these processed junk type foods intuitively. And if you can't, then that means you're not an intuitive eater. Basically, you should be able to have the cake and just have a little bit of cake. But some people would be better off just not having the cake, because having the cake will create factors in their body that create a completely different metabolic state that then you have to fight against. I'm all about the intuition coming in with knowing how you exist in your relationship to food and fasting and knowing what you need. Do you need systems or not, do you need rules or not? And then living within that. And so, it sounds like for Heidi, coming up with a more like picking an actual system to stick to might be something that would work well for her.

Cynthia Thurlow: Absolutely.

Melanie Avalon: All right. Well, this has been absolutely wonderful. So, a few things for listeners before we go. If you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. The show will have all the links, that will be at ifpodcast.com/episode285. And again, by the time this comes out, we mentioned Athletic Greens, which is a new supporter on the podcast and the amazing offer from them will be in the ads, so listen to that. You can follow us on Instagram. We are @ifpodcast, I'm @melanieavalon. Cynthia is @cynthia_thurlow_. Yes, I think that is all the things. Anything from you, Cynthia, before we go?

Cynthia Thurlow: No, keep the great questions coming. We've been really enjoying all of the feedback and great questions we've been receiving. So, keep them coming.

Melanie Avalon: I cannot agree more. All right. Well, enjoy the rest of your evening, and I will talk to you next week.

Cynthia Thurlow: Sounds good. Bye.

Melanie Avalon: Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice, and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes.

We couldn't do this without our amazing team. Administration by Sharon Merriman editing by Podcast Doctors. Show notes and artwork by Brianna Joyner. Transcripts by SpeechDocs. And original theme composed by Leland Cox and recomposed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

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Sep 25

Episode 284: Adrenal Fatigue, Hormetic Stress, Scent Memory, Menopause, Hormone Replacement Therapy, Tips And Tricks For New Fasters, And More!

Intermittent Fasting

Welcome to Episode 284 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

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To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get Two, 10 Oz New York Strip Steaks And 8 Oz Of Lobster Claw And Knuckle Meat Free In Your First Order.

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Listener Q&A: Bo - Adrenal Fatigue & IF

Ep. 216 The Science Behind Stress and How to Create Sustainable Change with Dr. Doni Wilson

The Melanie Avalon Biohacking Podcast Episode #164 - Ari Whitten

Master Your Stress, Reset Your Health: The Personalized Program to Calm Anxiety, Boost Energy, and Beat Burnout

Listener Q&A: Gretchen - Smells

Listener Q&A: Ute - Menopause

Ep. 211 – Addressing the Root Cause of Hormonal Imbalances with Dr. Sara Gottfried

Ep. 220 A Detailed Guide To Healthy Hormones With Dr. Lara Briden

Ep. 227 The Upgrade: A Unique Perspective on Perimenopause and Menopause with Dr. Louann Brizendine

Hormone Repair Manual: Every Woman's Guide to Healthy Hormones After 40

The Hormone Cure: Reclaim Balance, Sleep and Sex Drive; Lose Weight; Feel Focused, Vital, and Energized Naturally with the Gottfried Protocol 

The Upgrade: How the Female Brain Gets Stronger and Better in Midlife and Beyond

AVALONX Magnesium 8: Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist, And Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

Listener Q&A: Sybil-Anne - Need help from South Africa

Listener Q&A: Cheyenne - Easing into a fast

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 284 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, nurse practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment, and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time and get ready for The Intermittent Fasting Podcast.

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Are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat? It makes sense because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly, one of the most influential factors in weight gain and it's not your food and it's not fasting, it's actually our skincare and makeup. As it turns out, Europe has banned over 1000 compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer and obesogens which literally can cause your body to store and gain weight. 

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You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow. Use the coupon code CLEAN for all 20, to get 20% off your first order. Also make sure to get on my clean beauty email list that's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. Definitely check it out, and you can join me in my Facebook group Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well. 

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Melanie Avalon: Hi, everybody, and welcome. This is Episode number 284 of the Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hi, Melanie, how are you? 

Melanie Avalon: I'm good. How about you? 

Cynthia Thurlow: Doing well, doing all the things. All the mom things, we're heading into week three of the school year and I feel maybe everything's-- the kids are getting settled back into a routine, I have a new driver in the household with exceedingly exorbitantly expensive car insurance, just to be able to allow him to drive, it's insane. He doesn't even have a car. 

Melanie Avalon:  But just because of the demographics that he falls into.

Cynthia Thurlow: Correct. We had to have a whole discussion about that. I was like it's the outliers of the population that generally are the ones that are more likely to have accidents, and especially young males, which is what you are. 

Melanie Avalon:  It's interesting that there's not more political backlash about stereotyping with insurance companies, even though it's based on data. But that could be a thing, that could be like a cancel the insurance companies. 

Cynthia Thurlow: We're fortunate. We have USAA because my father was many years ago served in the navy during Vietnam. I told my husband, "It'd be way worse if we didn't have USAA." So, I don't even want to complain however, I said, I'm not stressing about this, because our wonderful 17-year-old is going to pay for his own insurance he has a certain amount he has to pay us every month and I feel like I'm teaching him some degree of responsibility. You should have seen the expression on his face when we said, "This is what you will owe us every month." He was like, "What?" I was like, "Yes, and you have a job and you have money in savings and I know how much you have in your savings; you can totally afford this."

Melanie Avalon: Wow. Nice, sets him up for life. 

Cynthia Thurlow: Exactly. 

Melanie Avalon: I've been having an interesting experience related to something that our audience loves. I forgot how often do you wear CGMs? Do you wear the one all the time still?

Cynthia Thurlow: No, probably the first 18 months I wore them near continuously. During the book launch, I just found that I would get like excited when I had press to do or podcasts or media work to do, but I would just watch my cortisol go up and my blood sugar would go up and it was like up down, up down all day long, so I didn't wear them for about two to three months. This summer I've had maybe once a month I've been wearing it, but I think I definitely have a better sense now of where I need to be in terms of my macros and managing my stress. So, to answer your question, there's a lot of utility but I don't wear it as much as I did two years ago. 

Melanie Avalon: Yeah, I was similar. When I first started using them a year ago or a year and a half ago, I went months [laughs] having one on all the time. Now it had been a while, but I actually reconnected with a friend from high school who comes here to Atlanta and she's into all of this stuff. So, we decided to put one on together and make a Reel and all of that stuff. So, this is the first time I'm wearing one. And for listeners who are not familiar, a CGM is a Continuous Glucose Monitor, it goes on your skin, super painless to put on and it measures your interstitial fluid to continuously measure your blood glucose levels, which can be incredible to see how you react to food and fasting and exercise. And as Cynthia, was talking about, adrenaline are stressful situations. But in any case, so I haven't worn one in about a year, and my blood sugar control seems to be substantially better from a year ago. I don't know if this is what it is, but I think it might be all the Emsculpt that I did, that I've been doing, building muscle.

Cynthia Thurlow: Yeah. I mean it makes sense, you know insulin sensitivity.

Melanie Avalon:  I just think we know that insulin resistance likely starts at the muscle and our muscles are a bank basically for glucose. Really, the only big thing I've changed in the past year is probably doing. I've been doing so much Emsculpt, which is muscle stimulation that literally builds muscle. I think I've built a lot of muscle; I'm just looking at my levels. My peaks are much lower than they were before and this is eating massive amounts of carbs, and then during the day just the average is probably like five or six or seven points lower. So, yeah, it could be other things as well, but it's cool to see. It's motivating. 

Cynthia Thurlow: I think it's also important just to, from the perspective of checking in with yourself to see how you're doing. I'll give you an example, so last night we had dinner at a neighbor's house. They know that I don't drink alcohol, so they came up with a mocktail. I literally when she started telling me what was in the mocktail, I was like, "Oh, Lord, I can't like politely not."

Melanie Avalon:  It was like all sugar? 

Cynthia Thurlow: Yes, it was pineapple juice. She was like, "Agave syrup." I literally like my husband, like kicked me under the table. So I just had to sip it and the whole time I was like, "Lord," I'm just going to have to make sure that I go to the gym tomorrow and lift heavy things. But, yeah, it was humorous to just imagine in my mind understanding like I'm just going to just eat protein tonight. I'm going to politely sip this drink. I'm going to dump it when no one's looking. But it was so thoughtful, I want to be very clear, but I don't normally consume sugary drinks ever. That's just not really my thing, but in terms of insulin sensitivity, it's one of those things. In my head, I was like, "Okay, what could I do after we leave here?" I'm like, "Okay, I can walk the dogs like." We would do that anyway, all the things. "Okay, tomorrow, I'm going to go to the gym. I'm going to fast a little longer, I'm going to lift heavy things." Like in my mind, I was already knowing the things I needed to do to help dispose of the said sugary beverage that I consumed. 

Melanie Avalon: That's so funny. Yeah, so out of curiosity, when you're in situations like that, at dinners where somebody has made something for you, what are your lines or rules? How often do you have the sip, or versus just saying, "No, thank you." 

Cynthia Thurlow: Well, I felt obligated to consume some of this because she specifically made sure to have a mocktail. So, I had actually brought a bottle of low sugar kombucha with me and I was like, "I'll just have this over ice, this will be fine." I would say that, something like that, knowing that I'm very physically active, very insulin sensitive, and like one half cup serving of that is not going to derail all the good things that I do. But it definitely makes me very cognizant of just how-- I don't want to use any negative work note or terminology, just how happy I am with my current lifestyle and how I eat food and consume beverages and I just don't realize how unusual sometimes my habits may be to other people. They were incredibly accommodating. They know I'm gluten free and I'm dairy free and so they had this lovely charcuterie platter that was out that I was trying to eat as much meat as I could, while I was sipping on said very sugary beverage, but I would say that there are some deal breakers like for me, I just don't do well with dairy. 

So, if I went to someone's house, and they had a very dairy heavy dessert, or were trying to incur, I would politely say, "I actually just don't do well with dairy." I think most people don't have a problem with that. I do find that the most triggering thing of all is when you just explain either, "No, I'm not drinking," or, "I don't drink alcohol." Then people don't know what to do with, and I was like, "I'm totally fine with that. You do what you need to do, and I'd be happy with a glass of water." I genuinely do pretty well with what works best for my body. 

The interesting thing was the guys were having some type of local pubs beer brew, and the mom was saying, "Oh, I don't normally have mocktails. But I didn't want you to feel left out." I was like, "No, no, I'm really good. I'm not triggered by what if everyone else is drinking, that's not a problem for me, but I think it comes down to--" first of all I have to genuinely be hungry to eat. I don't ever eat at someone's house just out of a sense of obligation, but I also am very grateful and try to be very appreciative. I don't want anyone to feel like the efforts they've made are not appreciated and valued. To me seed oils are probably at the top of my list of things, I really try to avoid as much as possible. So, I'm the person that will sometimes come to someone's house and I'll make a wonderful salad dressing, because then I have some control over what's in it. But I would say the other thing is, if I'm at all concerned about something not meeting my needs, like desserts are easy to pass up, alcohol is easy to pass up, it's usually when you sit down, and I'm sure any listeners probably have experienced this, you go to someone's house, and they have a bunch of salad dressings out and most conventional salad dressings are not going to meet my needs, so sometimes I'll just ask for olive oil, and vinegar, and people generally don't have an issue with that either. 

I don't want to sound like I'm one of those unappreciative guests. I'm generally very easy, but I think all of us have to figure out, how to navigate those social situations and not feel like you're a weirdo. 

Melanie Avalon: Yeah, I think it's such an important topic, because I just think it's something so many people struggle with. Honestly, I think it can be one of the hardest things about any dietary change or protocol that you're adhering to. And I hadn't really thought about it before, but the similarity between not drinking is really similar to like, if a person is fasting, not eating, I get so many DMs about this, whenever I post pictures of me at events or parties, where there's obviously food, I just normally don't eat anything. This is for the fasting, not for the alcohol related thing, unless it's like a dinner I'm going to where I can like order specifically what I want to order. But it took me a long time to get to the place where I am now. I don't know if I'm still like a little bit insecure about it, but I mostly just don't care. I feel pretty comfortable in just saying like, "No, I'm not eating right now."

Cynthia Thurlow: I think that's important, irrespective of where we are, who we are, what we're doing, just feeling comfortable with your decisions and not feeling a sense of obligation. One of the things I've really been working on the last few years is, I grew up in a family with a lot of trauma. So, the way that I that I mentally work through all that in my childhood and young adulthood was to be the people pleaser, and to always be the good kid and the kid that never got into trouble and got good grades. So, my people pleasing tendencies I've been actively really working on the last several years. Sometimes I'm just okay saying, "No, I appreciate that. But I'm not interested in having that." And feeling very comfortable and not feeling like I have to explain myself and I think that's a beautiful thing to get to that point. So, I love that you stand your ground and advocate for what you and your lifestyle need.

Melanie Avalon: I'm glad you said that, because that's what I have found to be the most minimal drama response because I think I used to feel the need to explain. It's funny, I'm just thinking about now how you've helped me with other things in life where you're like, "You don't have to explain, you can just say no," but I think I did used to feel the need to explain and now I normally say, "Thank you. I'm good." Normally that just does it. Sometimes there'll be follow up questions, "Oh, are you not hungry?" or "Are you not eating," or, "Why?" And then you have-- 

Cynthia Thurlow: I think it's a sense of you just want to make people feel inclusive. I know if I had someone at my house and they were abstaining from eating-- I just want to make sure like, do you have options and you feel good about the options that are available and as long as they're good, I'm like, "Okay, we're all adults." We're all adulting we have to figure out what works for us. 

Melanie Avalon: Exactly. So, I will give a link for listeners if they would like to get a CGM, though. Oh, which by the way, CGM, if you were that to a party, you will get a lot of questions.

Cynthia Thurlow: Yes, you will. 

Melanie Avalon: Our link for it, you can get $30 off. Just go to nutrisense.io/ifpodcast, and that is good for any of the subscription programs that they have. The subscription programs are more cost effective, so we definitely recommend going that route especially, you'll probably find it's hard to do it just once because it lasts for two weeks. So, you can do it just once, but a lot of people want to keep it on for a little bit.

Cynthia Thurlow: Very insightful. 

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Melanie Avalon: Okie-dokie. Shall we jump into questions for today? 

Cynthia Thurlow: Absolutely.

Melanie Avalon: To start things off, we have a question from Bo. The subject is, "Adrenal Fatigue and IF." Bo says, "Hello, first off, thank you both for guiding me through my first few months of IF. I started in September 19th of 2018. I don't think I could have gotten through my first couple of months without binge listening to your podcast, joining both of your groups on Facebook and listening to both of your books as well." By the way, this question was written when Gin was still hosting the podcast." She says, "Thank you for all the resources, also giving up stevia in September was probably one of the best things I've done. Thank you, Gin, I will most likely never ingest stevia again. I would choose honey or maple any day. I have been paleo-ish, mainly gluten free, dairy free, wholefoods approach for several years now, and even with my clean diet a couple of years ago, I was diagnosed and treating hypothyroidism. More recently after starting IF, I was diagnosed with the dreaded adrenal fatigue.

Even though I am treating both adrenal fatigue and hypothyroidism and doing IF 19:5 to 17:7, I'm still not losing weight. I originally lost five pounds the first couple of weeks and since then nothing. I'm about 15 to 20 pounds away from my ideal weight and feeling my best body. Since starting my IF lifestyle, I've gone down the rabbit hole of health-related podcasts, all the usual suspects in the keto/paleo sphere. I've heard them mention not to do IF with adrenal fatigue, what are your thoughts? My doctor, who is treating my adrenal fatigue says to listen to my body and see how I feel with IF and my energy levels. My energy levels are always pretty wonky, sometimes stable, other days awful, but never that amazing energy and mental clarity that you both talk about all the time. 

I'm wondering if I should focus on healing my adrenals, then come back to IF when they heal in a few months. Do you know if IF is too stressful for adrenal fatigue? Maybe this is why I'm not losing weight. Thank you for your help. Big hugs, Bo." 

Cynthia Thurlow: Well, Bo, I think you've answered your question here. First and foremost, for listeners, when we hear the term adrenal fatigue, it's really not adrenal fatigue. It's Hypothalamus-Pituitary-Adrenal Axis Dysregulation, which is a big fancy way of saying, your brain which oversees communication with glands and different organs in the body. As we are transitioning, I don't know Bo's age, so Bo might be in perimenopause, might be in menopause, we don't know but that's when women tend to be much more susceptible to this dysregulation. What drives a lot of HPA dysregulation is stress and inflammation and insulin resistance. There's many, many factors that play into this. I find that our modern-day lifestyles are a huge contributing issue, so I'm grateful that you're working with a knowledgeable physician, number one. 

Number two, even in my book, I talk a lot about adrenal and thyroid health and how important it is? I would be the first person to say that you really have to view intermittent fasting as a form of hormesis, so that's a beneficial stress in the right amount at this right time and based on what you have shared here, and again, I'm not giving medical advice, I would defer to your primary care provider internist functional medicine person that you're that you're seeing, but I would not be adding in more stress when your body is already overstressed. Whether it's an underactive thyroid, you have insulin resistance, you just went through a divorce, a hospitalization, you had a big move. Goodness, the pandemic hasn't helped anybody, any of these things can really overtax the body. And from my perspective, depending on what life stage you're in whether or not you're still menstruating, I really think you need to focus in on healing your body before you start adding in additional stressors. Another good resource for you, I interviewed Dr. Doni Wilson earlier this year, she has a great book called Master Your Stress, that you can find on Amazon and we'll put a link to that. 

I did a great podcast that we'll link in the show notes as well. She talks a lot about, you know, she has a very specific methodology on how she supports her patients when they are going through this specific type of stressors, how to manage it. She's not a fan of utilizing intermittent fasting when people are still healing. I would probably say that I would be in 100% alignment on that. That's not to suggest that doing 12 hours of digestive rest is a bad thing, but when you think about intermittent fasting as a form of beneficial stress, when your body's already too stressed, it's probably the time to give it a rest and then later reintroduced when you're feeling consistent energy, sleeping well, just the fact that your weight loss resistant tells me that your body has some degree of inflammation and figuring out why your body is so inflamed is going to be an important piece of that puzzle. I hope that helps. 

Melanie Avalon: Awesome. Yes, I'll just add to that. I was curious how you're going to start off or how are you going to approach the adrenal fatigue concept because it's interesting how debated it is, even in our world, just as far as does it exist? Does it not exist? Is it a real thing? I recently interviewed Ari Whitten. He's kind of known for his book on red light therapy, but his newest book is called Eat for Energy. He actually opens the book by talking about his experience with being diagnosed with adrenal fatigue, and then researching it and realizing that in the actual scientific studies and literature, it's hard to find support that it's an actual thing. That your adrenals are actually fatigued, or that's actually a concept of what's going on. 

I was just looking at a quote, he says in his book, "The vast majority of studies that tested adrenal function and cortisol levels and those with chronic fatigue conditions versus normal healthy people found no differences whatsoever in adrenal function or cortisol levels." But the larger picture that it goes to from that is that people get into the states of fatigue and over stress, and he breaks it down to basically the mitochondria, not being able to adequately deal with all the stressors that were exposed to. Cynthia was saying, intermittent fasting is a hormetic stress, but of course, based on your entire stress bucket, it may or may not be too much for you. I think it's interesting, we talked about this recently, when we were talking about some of Dr. Sarah Ballantyne's work, we can put a link in the show notes to that episode. But we were looking at some studies on intermittent fasting and how it affected stress biomarkers.

And in those studies, they actually found that it was contrary to what they thought they were going to find, but they actually found that intermittent fasting, at least in the setup of those studies, it overall encouraged parasympathetic tone, which is actually the opposite of the overly stress state. All of that to say is, I think I've said a lot of stuff, I think is very individual. So basically, for some people, and how you're doing intermittent fasting, it may be too stressful with your life situations and your "adrenal fatigue," depending on what that actually is or for some people it may be that it fits in well with their life, and it actually alleviates some of their stress and helps their "adrenal fatigue." I think it's just really, really individual so I think you have to do a more comprehensive picture of how you are reacting to it, which is what her doctor told her exactly.

Cynthia Thurlow: Bio-individuality rules, as it always goes.

Melanie Avalon: Yeah. I was thinking about this actually, yesterday. Why was I thinking about this? Oh, I'm prepping to interview Dr. Nayan Patel, he wrote a book about called, The Glutathione Revolution, all about glutathione. I was reading my notes on antioxidants and oxidative stress. He has a chapter about, what type of stress does glutathione help? I was just contemplating, does mental stress create free radicals? I'm on a tangent right now, but does it create free radicals and physical things like that, or is it that it's a taxing stressful situation that leads to the same stressed-out end angle, that physical stress leads to.

Cynthia Thurlow: It's a good question. I think it could be either. The other thing that I would just tack in there before I forget. I, at one point trained with one of the big functional medicine doc's Andrew Hyman, and he was talking to me about adrenal fatigue. In the context of people are really getting this wrong, it's really related to the hippocampus, which is this part of the brain and how sometimes the hippocampus doesn't heal from the insult or the stress that people are experiencing, which can leave them in this kind of downward spiral. This is, I promise, relevant to what you're saying about Ari's book. But you start thinking about if most people over the age of 40 have got mitochondrial dysfunction, is it any surprise that I see prolific amounts of women, north of 35, north of 40, that are just so exhausted. 

I think it's a combination in modern day lifestyles and depletion of role of antioxidants, depletion of glutathione. I literally was looking at a research article this weekend, talking about how the past two years, like our longevity here in the United States is actually getting worse and not better, but that probably isn't a surprise. But they were looking at all these like retrospectives, like what's the longevity of someone in Japan or in Korea versus the United States, it's quite significant. I start thinking about these kinds of chronic insults, it's like a bucket, the bucket continues to fill year after year. And then we just get to a point where our bodies are not as stress resilient. 

We talk about adrenal fatigue, but really, we're talking about the accumulation of many, many years of insults to the body, whether we're cognizant of it or not, and the resultant fatigue that comes out of that. And for many people, they don't get the answers they want or deserve to get, and so I love that you're introducing so many of the listeners to different perspectives on how people navigate these changes. I will have Ari on, but not until I'm going to say February, because we had to reschedule because he got scheduled on my birthday, which is a whole separate tangential conversation. I don't work on my birthday. That's a standing rule. 

Melanie Avalon: Neither. I'm so glad you elaborated on that, because I should probably share his central thesis, which is that the mitochondria basically have two roles. They have a dual role. They have the energy production role, and then they have a defensive stress sensing role. They can't really do both at the same time. So, if they're in the stress mode, the stress mode reacting to threats, it shuts down energy production. So, yeah, I'm excited for you too, to interview him. It's a really good book. 

Cynthia Thurlow: Yeah. I mean it's definitely I feel very grateful, as I know you do that. We get opportunities sometimes to read people's books before they are ever officially published. As I'm looking at the voluminous amount of books, I have in my study I feel very grateful, because there's always opportunities to learn something that not only can you share with listeners, but you can take a bit of that and apply it to your own lifestyle. I'm looking at James Nestor book Breath, because it's such a bright cover, it stands out amongst all these other muted books. Makes you realize, every book I read, I try to take something away to be able to share with listeners, share with my community, improve my quality of life, improve someone else's quality life and that's really what it's all about. 

Melanie Avalon: I cannot agree more. That example of that cortisol sentence from Ari's book was something that really, really stuck with me, because I had never read that. That he had reviewed the literature and that the majority of it didn't find substantial differences in cortisol levels, which I actually find that really-- I think it's very reassuring, because I think a lot of people get a little bit stressed about being stressed. I do think cortisol levels can be an issue, like you were talking about how they are an issue for people, but I think it's nice to know that maybe it's not quite as intense as we think it might be, because I think it can be very easy to get into a just like an overwhelmed, stressed state about our state of stress and like worried that our cortisol levels are super high, and we should address it, but we can do that without fear. I think just hearing that one sentence, I mean, it made me feel a lot better. 

Cynthia Thurlow: Absolutely.

Melanie Avalon: Random thing about James. I didn't realize he wrote a book that I had years ago and now I want to-- I don't know if I actually read it though if I just bought it. But now I want to see if he wants to come on to talk about this book, even though it's like one of his really old works. He wrote a book called Get High Now (without drugs). Have you heard of this book? 

Cynthia Thurlow: I have not.

Melanie Avalon: It's like all of the different non drug related things that create a different state of consciousness. From the description, he says, "Lucid dreaming, optical and auditory illusions, controlled breathing, meditation, time compression, physical and mental exercises." I want to invite him on for this. I wonder how often authors get invited to do an interview on one of their old-- this is a 2009 book.

Cynthia Thurlow: I bet you, he'd be very flattered. I found him to be delightfully down to earth. Given his-- would I perceive to be definitely one of the more well-respected science writers that’s out there.

Melanie Avalon: I'm going to reach out. So okie-dokie. Shall we go on to our next question? 

Cynthia Thurlow: Absolutely. This is from Gretchen, and the subject is "Smells." "Thank you so much for your podcast. I've been listening to it nonstop and started my IF journey on mundane. My question about smells. We're spending most of our time at home nowadays. And my husband loves to cook big breakfast and lunches. He's downstairs making something delicious for lunch, and my mouth is watering from the glorious aromas. Can this cause insulin levels to spike just as artificially sweetened beverages can? I've been able to breezed the days without hunger unless he is cooking. "

Melanie Avalon: All right, Gretchen, thank you so much for your question. I believe my thoughts on this answer are, yes. We've talked about this before on the show but it's to the same extent as the artificial sweeteners. What I think is important to understand is, I think people think with insulin release, that it's just one process so it's released or it's not released. And once it's released, it's releasing. But there's actually two phases to insulin release. There's the cephalic phase insulin response, which basically your pancreas always has a little bit of insulin ready and waiting and it taps out. There's only so much there and that's for when you smell something or when you're anticipating about to eat, so it releases a little bit of insulin, but then for the actual, like insulin bolus that keeps going in a sustained, that's created then in the pancreas, and that's more when you're actually eating. I've looked at a study before and I think we've talked about on a prior show. 

Basically, yes, the smells can likely release some insulin, but it's probably not going to start that second train of insulin production. Meaning, you can basically wait it out, if that makes sense. Do you have thoughts, Cynthia?

Cynthia Thurlow: I would agree with you too. I think that we don't want to navigate our lives feeling fearful that if we smell something delicious, that somehow we've broken our fast or derailed our fast. We have to think big context, like when we're talking about breaking your fast, I really think it needs to come down to ingesting something as opposed to smelling something. I think we would otherwise go through our lives, not just enjoying, being present, being around family, being around friends, being in a work environment, and being fearful, we're going to smell something delicious. I think we have to think about the big picture. Generally, I look at it, have you ingested the food? That is more important to me than if you just smelled the food because the cephalic phase insulin response, yes, that's there. But I have to believe that our bodies, it's more sophisticated than that. I mean, you will get this small release in response to smelling something delicious but that's really irrelevant. It's more about what habits are going to break your fast and ingesting the food we'll do that.

Melanie Avalon:  Exactly. I'm trying to remember because there was definitely [sighs] there was a study I had read and it was about people smelling chocolate, or it was literally asking this exact question, and what were the effects? The answer was that, yes, it likely releases insulin, but it's just that small amount. And it's something that you weighed out, I'm really glad that you drew attention to the practicality of it all. If you couldn't smell things, that's no, not practical.

Cynthia Thurlow: It's interesting because there's-- and I don’t mean to speak over you. One of the most powerful connections to memories that we have, is there an olfactory system. If I smell carrots, I instantly and brought back to my grandparent's garden in Colorado. Our memories are so intertwined with smells, and our olfactory system, I think it's really important that we not try to diminish those experiences. I think that's just important to state that it's really tied in with memories. There are certain smells like wonderful, delicious smells related to food that bring me back to happy times in my childhood or young adult adulthood. And you don't want to diminish those. I think that's important. 

Melanie Avalon: I could not agree more. I'm trying to remember Mark Schatzker, who I keep talking about with The End of Craving and The Dorito Effect. I learned in that book that we have more DNA devoted to our nose and the mouth than any other part of the human body which is fascinating. It's definitely something that we should be engaging in. 

Cynthia Thurlow: Yeah. Exactly. It's the same thing and I'm sure you get these questions, where people are paranoid to brush their teeth or they're paranoid to take a medication that's prescribed with for fear that it's breaking a fast. And I always say let's think big picture. Like not brushing your teeth, the ramifications of that are greater than brushing your teeth, provided you're not swallowing your toothpaste, which I don't think anyone--that's an adult does that. I know toddlers are notorious for that. I just think we always have to be focused on the big picture. I think that's what's most important.

Melanie Avalon: I cannot agree more. All right, so we can go on to our next question. I don't know how to say her name, It's U-T-E, Ute maybe.

Cynthia Thurlow: Ute, that sounds good. 

Melanie Avalon: She's from Germany. The subject is "Menopause." Ute says, "Hello, ladies. I discovered your podcast last weekend while researching a healthy lifestyle that I can maintain effortlessly. Calorie counting is so depressing and it drives me bonkers. Thank you for all the great information and tips. Since I'm going through menopause, fun times, I wonder if there is some advice you can give." That's a very wide-open question. This is a Cynthia question.

Cynthia Thurlow: Yeah. Truly. Well, I think it's always the reframe. We shouldn't perceive that menopause or perimenopause is a negative thing. I mean, you're going through reverse puberty, but there's so many benefits to not having to worry about getting pregnant anymore, you're not having a cycle every month, your fertility is waxing and waning, and then it's gone. But to me, being at a different stage in my life, I think it's really empowering. I have the bandwidth to do things I wasn't capable of doing 15 or 20 years ago. So, in terms of resources, I would say I've done a lot of podcast around perimenopause and menopause, most recently with Dr. Louann Brizendine, who is a neuropsychiatrist, trained at Harvard. I mean, she's absolutely brilliant. She wrote a book called The Upgrade. The upgrade is menopause, but she said, if we really reflect on the fact that a lot of the terminology around women and aging was created by men, generally, male physicians and the pharmaceutical industry.

She does a really beautiful job of helping us reframe what's happening in our bodies, so we are no longer menstruating or we're getting close to no longer menstruating. We're not in a position where we can become pregnant without technology, that there are changes to our brain, there's changes to the way we perceive the world. There's changes to the way our body responds to certain macronutrients and exercise and sleep. There's lots of really wonderful books. I would say, The Upgrade is definitely a favorite. 

I would say Dr. Lara Briden, has a really excellent book called Hormone Repair Manual. That's Dr. Lara Briden, and I've had her on the podcast. Dr. Sara Gottfried has some fantastic resources, probably my favorite book of hers is The Hormone Cure. Then I think about researchers like Dr. Lisa Mosconi, who is an Alzheimer's brain health researcher at Cornell, she wrote a book called, The XX Brain that I recommend almost daily. I would say those are really great resources and I've done podcasts with each one of them except Dr. Mosconi because she's doing so much research, I literally harass her publicist, probably once a month. I'm going to eventually get her on the podcast. I think a lot of menopause is reframing things. Hot flashes, weight, gain, inflammation, etc., are largely a byproduct of how well we take care of ourselves. So, there's always room for improvement and I find most women, usually within a year or two going through menopause, their symptoms will settle down. 

It's important to understand the things we need to prioritize in this time in our life. I think about sleep quality, stress management, anti-inflammatory nutrition, that could look different for most everyone. But I find the most inflammatory foods for most women are dairy and gluten and alcohol and sugar. Let me put an apostrophe time seven next to sugar. And understanding that your relationship with certain types of foods are going to shift really focusing on, they call it neat, but the exercise we do outside of formal exercise is important. Walking, just being active, not sitting on your rear end all day long and then lifting weights. 

I see so many women that I'm inspired by on social media, there's the good and the bad with social media, but there are definitely average everyday women that I see on social media that are just killing it in their 40s, 50s, 60s, and beyond, like doing amazing things. It's a time of tremendous creativity, it's a time to really reflect on your life and your contributions. And so I would say, I hope that those resources are helpful, we'll make sure that we link those podcasts, and those books in the show notes, so that will be available to you as well. 

Melanie, is there anything that you'd like to add? I know that you're not in this stage of life, but I'm sure you probably interviewing so many people, you probably have some suggestions as well.

Melanie Avalon: Resources wise, that was very comprehensive and amazing. I'm actually just personally, I'm very curious what my experience will be when I go through menopause because I feel like when I had my period of heavy metal toxicity, like to the extreme mercury toxicity that I exhibited, it was like all the symptoms that I see listed as menopausal symptoms. Just because of the, I guess, the hormonal dysregulation from that. I've been very curious when I go through menopause, if it will be. I remember when I was in that I was like, "When I go through menopause, it's going to be a breeze once--" I guess if I can get through this. But I would get all of that like hot flashes and fluctuations and insomnia, and create, like just so many, all of the things. So, that's not very helpful. It's just my experience.

Cynthia Thurlow: I think the better you take care of yourself in perimenopause. From 35 up, the better you take care of your nutrition and your sleep and your stress management and doing the right kinds of exercise, the easier that transition will be. I would say for most people, it's bumpy, because they still want to act and behave like they did at 20 and you can't. And that's not a bad thing. I don't want to eat the way I did when I was 20, I don't want to live the way I did when I was 20, and so once I kind of understood, I had to eliminate some foods, focus on other areas really prioritize sleep, which I affectionately call an art form, because truly it is. Melanie, at some point, I'll have to tell you about my new sleep device that I'm using that you'll probably laugh about. But we'll talk more about it. 

Melanie Avalon: Do I know what it is? 

Cynthia Thurlow: Probably not, because I haven't talked a lot about it on social media. But I have something called Somnox, S-O-M-N-O-X. It looks like a stuffed bean. Like it's the shape of a bean or like a mitochondria. That's probably a better more apt description. You hug it while you're starting to fall asleep, and so I set mine for 30 minutes, and it actually will adjust to your breathing pattern. And what it's doing is stimulating the autonomic nervous system parasympathetic. I've doubled my deep sleep. 

Melanie Avalon: Is it a similar concept to the Apollo Neuro where it's using the vibrations? 

Cynthia Thurlow: Yeah. It's different. It's different than the Apollo Neuro which obviously I love, and love, love, love that. That's certainly very helpful for stress reduction. But for me, I've just been using it before I go to sleep. And my husband is like, "Oh, my God, what's next for you? You sleep with the sleep mask, you've got your blue blockers--[laughs] You've got all these things that you do and you sleep with your Oura ring." But it's honest to goodness, it's doubled my sleep. Let me be clear, they gifted this to me, I was not even aware of it. They gifted to me, and this is my objective opinion. I don't have an affiliate account with them. I mean, I don't get anything for talking about it. Just really have been impressed with the technology and then it turns off. It's not exposing me to anything that's negative. But, yeah, I now sleep with what looks like a little mitochondria tucked up against my chest. 

Melanie Avalon: Can you connect me to them? I want to try this. I'm surprised they haven't reached out to me. That's right up my alley. 

Cynthia Thurlow: I know. It's completely random that they reached out because sometimes I'm sure this happens to you too. People reach out to you randomly and sometimes I'm just very polite and say, "I don't really think I would use that. I don't want to waste your time or your resources sending me something that I don't think I would use or support." I looked at and I was like, "Oh, it can't hurt." My husband was like, "What next?" I was like, "I don't know." I just know that’s helping my deep sleep and that for me as a middle-aged woman is pretty incredible. 

Melanie Avalon: What was it called again? Somnox.

Cynthia Thurlow: It's Somnox, S-O-M-N-O-X. I think it's a German based company. 

Melanie Avalon:  That is so cool.

Cynthia Thurlow: That's very cool. Except my husband is now embarrassed. He's like, "What is that thing?" I'm like, "It's my little Somnox."

Melanie Avalon: Oh, my goodness. What color is it? 

Cynthia Thurlow: It's blue. It's a delightful pleasing blue. It's blue like dark blue and light blue. 

Melanie Avalon:  You hug it, basically. 

Cynthia Thurlow: Yeah. It's curved, so it's designed to just fit in to your chest as you sleep, so I turn on my side. I do like 30 minutes and it acclimates to my breathing and I just fall blissfully asleep. It's amazing. There's no nothing else that's changed. 

Melanie Avalon: I need this. Okay, this is great. Wow. To-do list. One other question, I don't even know if I should ask it because it's a big question but with the menopause stuff, do you find people benefit from HRT? 

Cynthia Thurlow: I do. I think the Women's Health Initiative came out in 2002. So right as I was finishing up my NP program, and the research that was done, and the points that were drawn from the research, there's a lot to unpack here. I did a great podcast with Dr. Avrum Bluming and Carol Tavris, talking about why estrogen matters. That's their book, but it basically explains what was flawed about this study. And it's really important that I just state an entire generation of clinicians, and an entire generation of women have been harmed by the way that this research was shared. We're just now getting to a point where I think most, if not all, clinicians are talking openly about the fact that there is benefit from replacing hormones that our bodies have naturally stopped producing. 

As an overall, like general statement, I do think women benefit from Bioidentical Hormone Replacement. I do. I myself take compounded, good Lord, compounded progesterone and compounded T4/T3. I have testosterone, I also have estrogen, I've got it all. I really do think for me personally that they help asleep, they help with inter kind of synergistically, each one of them is helping me with different aspects of navigating these years. But the thing that I get most concerned about, and anyone that's listening, that's 35 and up, I worry the most about cognitive function because Alzheimer's and dementia, they don't start in your 70s or 60s, the groundwork is laid many years before. This is important 30s, 40s, 50s, how well we take care of ourselves sets us up for developing disorders of cognition. 

For me, I'm most concerned about brain health, and then secondarily to that bone and heart health, of course. Then beyond that, just wanting to be able to navigate every stage of life that I'm in, I want to be able to enjoy my life and not feel like I can't be 100%. So, getting back to your original question, I do. I think it's all about finding practitioners that are not only capable, but current and openminded to help you find the combination of medications that are best for you. Like I've now gotten to a point that anything that's made conventionally just has not worked well for me. Now we just finally stopped Synthroid and Cytomel, now I'm on compounded T4 and T3 and my functional medicine doc told me I have the most "curious thyroid panel" he's ever seen. With that being said, everyone that's listening, I have women who are petrified of hormones, I have women who are openminded to hormones. I think it's just important to have those conversations, like whether it's with your GYN or your internist or your girlfriend, just understand there are options, you don't have to suffer. 

Melanie Avalon:  I'm really, really happy to hear you say that. That was my understanding of that, of the Women's Health Initiative because basically, the takeaway was they said it encouraged, was it breast cancer? It was not done correctly and interpreted correctly and created a potentially-- Yeah, well, everything that you said, misled.

Cynthia Thurlow: It's unfortunate because the samples, the study participants were older, they weren't 49, 50, 52, they were in their 60s. Many of them had been smokers, they had high blood pressure, they were diabetic, they were obese. They weren't a healthy population to start with and they used Premarin and they use Progestin, which is synthetic form of progesterone. It's interesting, everyone knows that you and I both love Huberman and Dr. Peter Attia, they had a really interesting discussion. Peter Attia was a guest on Huberman lab. Fairly recently, in about an hour in to the podcast interview, Peter Attia effectively stated that this was one of the greatest disasters he's ever witnessed as a clinician, that it has such profound implication and impact. 

I look at my mother's generation, my mom is 76 and has terrible osteoporosis and we're starting to see some degree of cognitive changes. It's unfortunate, because she thought, "Oh, if I'm using vaginal estrogen that's going to protect me." And I said, "It doesn't protect your bones, maybe your vagina," which I mean, let's be honest, that's an important part of being a woman, but there was just not good information given to these women. They were not fully informed and so I think we just have a whole generation of women and clinicians that are fearful about prescribing hormones. I almost get a question about this every single day on social media, which tells me that we need to continue talking about it. It's important for people to know that working with a talented, competent clinician, if you're in a situation where you need hormonal therapies that there are people out there that can help you through that. 

Melanie Avalon: Yeah. I'm just thinking, I don't know if I'll be able to articulate this, but it was an effect that was very pervasive because I feel like even me, even before I was super steeped in the health and wellness sphere, and even when I was younger when I wasn't even thinking about this type of stuff, there was a vibe surrounding HRT that it was, like not a good thing to do. I just think it really, really got into culture, which is kind of a shame that it went that way. 

Cynthia Thurlow: Absolutely, because we have a generation of women that are struggling. It's not like the conversation I had with Dr. Louann Brizendine, and she's based out of California. She's almost 70, she doesn't look at first of all, and she's like, "I have amazing bone strength." She's been on HRT for almost 20 years and she's a tiny petite person and she said, "I have amazing bone strength. I've got very healthy bone, but I credit that to HRT."

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All right. Shall we answer one more question? 

Cynthia Thurlow: Absolutely. This is from Sybil Ann, subject is, "Need help from South Africa." "Hi, first of all, thanks so much for all the effort you put into the podcast. Love, love, love the podcast. I'm not sure how to 100% phrase my question, but what strategies do you or did you use to stick to the plan. I started out really strong. The first two weeks, I almost effortlessly fasted 18 to 20 hours daily and then all of a sudden it became difficult. It's like I have a mental block, I can't move past. Nothing significant has happened in my life, so it's not related to stress or anything. I follow all recommendations and fast, totally clean. Did this ever happen to you? You wake up one day and fasting seems hard. I don't understand how I could do so well and feel so good, and then a few weeks in, feel different. Did this ever happen to you? Any advice or tips would be greatly appreciated. Thanks so much for taking the time to read my question. Best regards, Sybil." 

Melanie Avalon:  All right, Sybil from South Africa. Thank you so much for the question. So, I do think this is a common thing that happens with people. It's not exactly the same thing but it's sort of how with even calorie restriction or normal diets or crash diets, people can sometimes do it really well in the beginning and then it becomes really, really hard. The reason that happens is because it's not sustainable, whatever dietary restriction that the person is doing. I think with fasting a lot that this can also happen where somebody starts intermittent fasting. In the beginning, it's great, they're losing weight, their adrenaline's probably up, they have energy. But then if the actual eating window is not a sustainable amount, then you're going to reach a point where your body's going to give signals to you that it's not a sustainable amount. 

This is the case I would really, like, where you just randomly one day it's hard, I believe it might be because you're actually not fueling adequately in your eating window. So, I would suggest one of two things, either having a longer eating window, so changing the fasting hours, or really addressing what you're eating in that eating window, making sure that you're getting adequate fuel, adequate protein, especially, depending on what macros you're doing. If you're doing a mixed diet, then this wouldn't really apply, but if you're doing a low carb diet, making sure you're getting ample fats to support your fast, if you're doing high carb, making sure you're getting enough calories in the form of the carbs. So yes, I think what happens, I've already said it, but it's people like going on adrenaline and doing well in the beginning, but their eating choices aren't actually sustainable. So that's what I would look at. Do you have thoughts? 

Cynthia Thurlow: Yeah. I mean, of course, I always come from the perspective, are you having a harder time with fasting depending on where you are in your menstrual cycle? Because it's much easier to do that when estrogen predominates in the follicular phase, which is in the beginning versus the week before your menstrual cycle. I do think when we are creating lifestyle change opportunities, we have to be really mindful of what is sustainable. Are you too restrictive? Are you not getting enough macros during your feeding window? Are you not sleeping well? Are you over exercising? Is there just too much stress going on in your personal life? I think sometimes we set really not necessarily unachievable, but not sustainable goals. And so I would really encourage you to think about what is something you can do for the rest of your life versus something for just a couple of weeks, because that's a really important distinction. 

For me, personally, if someone said to me I could never have dark chocolate for the rest of my life, that would not be sustainable, versus if I say to myself, I'm allowed to have a small piece of dark chocolate every other day, and I can sustain that, then that is a sustainable goal. I'm giving a terrible example. Dark chocolate is my one vice. If people don't know that already, that's like my one vice in life. It'd be very hard to give that up. So, I think when you're looking at a plan and you're creating changes, sometimes I see people doing too many things all at once. Meaning, they're trying to improve their sleep, they're trying to exercise or trying to fast, they're trying to do all the things all at once. What they really need to do is pick one thing at a time, master that and then add more things and that is much more achievable and sustainable. 

Melanie Avalon: Yeah. I cannot agree more. So hopefully that's helpful. All right. One more question we can sneak in. This comes from Cheyenne, and the subject is "Easing into a fast." Cheyenne says, "Hello, I've been listening to your podcast for just a few days and love it. I've been practicing IF for about 9-years. For most of those years, I had great success and practicing a 16:8 fast and have been able to maintain a healthy weight. That said, I've been slowly putting on weight for the last year or so, I'm starting to think it has to do with my age. I'm currently 41. After listening to your podcast, I thought I might try to increase my fasting to a 24 or one meal a day. It was tough. About two hours before I was to break my fast, I got really cold in my extremities and became pretty weak. When I finally broke my fast, I didn't binge but I was extremely tired and had to go to sleep. My question is how do I ease into a longer fast comfortably? P.S. I did have my thyroid checked, and though it's on the low side, it's still a normal range and my doctor is a big proponent of IF. Thanks so much. 

Cynthia Thurlow: This is a great question. This goes back to something a theme that I am starting to talk about more openly on social media. The presumption that what you have to do is fast longer and restrict more and what it may mean because you're in that perimenopausal age range, it can be a lot of factors, that could be why you're becoming weight loss resistant. Have you lost muscle mass. Melanie and I were talking earlier about the loss of insulin sensitivity with less muscle that we have and we start to lose muscle after the age of 40. And depending on who you're talking to, it could be 3%. It's pretty significant and it starts to just accelerate like a freight train. What's your stress management like? What's your sleep quality like? Are you exercising? Are you lifting weights? Are you having an anti-inflammatory diet? I don't like short feeding windows, because you're never going to be able to hit your protein macros. I would encourage you to explore those other lifestyle pieces first. If you decide for yourself that you got all those things ratcheted in, I would not be doing a short OMAD type eating methodology. I would not be doing that every day. It's going to be very hard to hit your protein macros, and you don't want to be losing insulin sensitivity and muscle mass, especially as you're heading into perimenopause and menopause. Melanie, what are your thoughts? 

Melanie Avalon: I think it's interesting, because people, like you basically just said this, but people when they have an issue with not losing weight, or not feeling like their diet is working, they think the answer is automatically fast more, like that's the answer. I personally think there's so much benefit that can go into looking at the food choices specifically. Especially, when people writing questions, I don't think she mentions at all what she's eating. When people don't mention actually what they're eating, then I feel there's possibly the potential for a lot of the benefits that you want to experience by addressing what you're eating rather than fasting more. If you're not eating a whole foods based diet, moving to a whole foods based diet. Like Cynthia said, really focusing on the protein, things like that can be huge. But then if you do want to fast for no reason-- so basically, she went from going nine years 16:8, jumping into a short eating window. I would suggest just slowly tightening it up and slowly approaching if you want to make a shorter eating window, so doing a 17:7, and then 18:6 and seeing how you feel going a little bit longer. 

There's nothing wrong with just fasting a little bit longer, you don't have to jump into a short eating window you could just add an extra hour here or there. Also, little hacks that you could do maybe fasting just a little bit longer, like adding an extra hour and really putting in some physical activity near the end of that fast, that can have a really beneficial effect for people, both for fat burning, as well as setting you up for your eating window, insulin sensitivity and things like that. So, yes, I would just take a different approach than the jumping all in to the short eating window approach. 

Cynthia Thurlow: I agree. I think and I hope that we will continue kind of investigating this triad that I'm seeing in a lot of women where the presumption is more fasting, more exercise, more food restriction is going to allow them to lose the weight they're frustrated with.

Melanie Avalon: Exactly. Awesome. All right, so this has been absolutely wonderful. So, a few things for listeners before we go. If you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. You can find the show notes, I feel like we talked about so much stuff in today's episode. I always feel bad for Brianna, our show notes creator, all the links we'll be sending her way to put into the show notes. They will be at ifpodcast.com/episode284. You can follow us on Instagram as well. That is @ifpodcast. I am @melanieavalon, Cynthia is @cynthia_thurlow_. Well, this has been absolutely wonderful. Anything from you, Cynthia, before we go.

Cynthia Thurlow: No, just we got through a lot of questions today. I think I always feel very productive when we can make that happen. 

Melanie Avalon: Same thing. All right. Well, I will talk to you next week. 

Cynthia Thurlow: Sounds good. 

Melanie Avalon: Bye. 

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and recomposed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription] 

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Sep 18

Episode 283: PCOS, Infertility, Stevia, Glucose Tolerance, Healthy Snacks, Polyunsaturated Fats, Fish Oil, And More!

Intermittent Fasting

Welcome to Episode 283 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

LMNT: For Fasting Or Low-Carb Diets Electrolytes Are Key For Relieving Hunger, Cramps, Headaches, Tiredness, And Dizziness. With No Sugar, Artificial Ingredients, Coloring, And Only 2 Grams Of Carbs Per Packet, Try LMNT For Complete And Total Hydration. For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase!

NUTRISENSE: Get Your Own Personal Continuous Glucose Monitor (CGM) To See How Your Blood Sugar Responds 24/7 To Your Food, Fasting, And Exercise! The Nutrisense CGM Program Helps You Interpret The Data And Take Charge Of Your Metabolic Health! Get $30 Off A CGM At Nutrisense.Io/Ifpodcast With The Code IFPODCAST!

FEALS: Feals Makes CBD Oil Which Satisfies ALL Of Melanie's Stringent Criteria: It's Premium, Full Spectrum, Organic, Tested, Pure CBD In MCT Oil! It's Delivered Directly To Your Doorstep. CBD Supports The Body's Natural Cannabinoid System, And Can Address An Array Of Issues, From Sleep To Stress To Chronic Pain, And More! Go To Feals.Com/Ifpodcast To Become A Member And Get 50% Off Your First Order, With Free Shipping!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

LMNT: For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase! Learn All About Electrolytes In Episode 237 - Our Interview With Robb Wolf!

IF45 Class

IF45 Coaching Certification program

Optimal Protein Podcast (Fast Keto) with Vanessa Spina

Use Coupon Code MELANIEAVALON or CYNTHIA For an exclusive discount at mdlogichealth.com!

NUTRISENSE: Get $30 Off A CGM At nutrisense.io/ifpodcast With The Code IFPODCAST!

Listener Q&A: Veronica - IF and PCOS

Ep. 221 Part 1- An Integrative Approach to PCOS and Menstrual Irregularities with Dr. Felice Gersh

Listener Q&A: Rebecca - Another Stevia question

Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance

FEALS: Go To feals.com/ifpodcast To Become A Member And Get 50% Off Your First Order, With Free Shipping!

Listener Q&A: Harper - Snack Suggestions

The Melanie Avalon Podcast Episode #61 - Dr. Cate Shanahan

Ep. 131 – Bucking the Biggest Medical Lie: How the Foundation for Your Good Health Starts with the Foods You Eat with Dr. Cate Shanahan

SHIELD YOUR BODY RADIATION SAFETY DAY: Go To shieldyourbody.com/rsd For FREE And Easy Ways You And Your Family Can Radically Reduce Your Exposure To EMF Radiation, Without Impacting Your Enjoyment Of Modern Technology, And Win A FREE $2000 Canopy! Use The Code Melanieavalon For 15% Off Sitewide At melanieavalon.com/syb.

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Transcript Text

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Sep 11

Episode 282: EMF Protection, Insulin Levels, IF Weight And Fat Gain, Heart Palpitations, Electrolytes, Hydration, Digestion Changes, And More!

Intermittent Fasting

Welcome to Episode 282 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

BUTCHERBOX: Grass-Fed Beef, Organic Chicken, Heritage Pork, Wild-Caught Seafood: Nutrient-Rich, Raised Sustainably The Way Nature Intended, And Shipped Straight To Your Door! For A Limited Time Go To butcherbox.com/ifpodcast And Get Free Chicken For A Year!!

SHIELD YOUR BODY RADIATION SAFETY DAY: Go To shieldyourbody.com/rsd For FREE And Easy Ways You And Your Family Can Radically Reduce Your Exposure To EMF Radiation, Without Impacting Your Enjoyment Of Modern Technology, And Win A FREE $2000 Canopy! Use The Code Melanieavalon For 15% Off Sitewide At melanieavalon.com/syb.

ATHLETIC GREENS: 75 High-Quality Vitamins, Minerals, Whole-Food Sourced Ingredients, Probiotics, And Adaptogens In One Delicious Scoop! Get A FREE 1 Year Supply Of Immune-Supporting Vitamin D AND 5 FREE Travel Packs With Your First Purchase At athleticgreens.com/ifpodcast!

 JOOVV: Like intermittent fasting, red light therapy can benefit the body on so many levels! It literally works on the mitochondrial level to help your cells generate more energy! Red light can help you burn fat (including targeted fat burning and stubborn fat!), contour your body, reduce fine lines and wrinkles, produce collagen for epic skin, support muscle recovery, reduce joint pain and inflammation, combat fatigue, help you sleep better, improve mood, and so much more!! These devices are literally LIFE CHANGING!! For A Limited Time Go To Joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get Free Chicken For A Year!!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

SHIELDYOURBODY: Use The Code Melanieavalon For 15% Off Sitewide At melanieavalon.com/syb.

The Melanie Avalon Biohacking Podcast Episode #122 - R Blank

ATHLETIC GREENS: Get A FREE 1 Year Supply Of Immune-Supporting Vitamin D AND 5 FREE Travel Packs With Your First Purchase At athleticgreens.com/ifpodcast!

Listener Q&A: Erica - Eating and insulin levels

Listener Q&A: Kathryn - IF Weight and Fat gain

The Melanie Avalon biohacking Podcast Episode #45: Glenn Livingston, Ph. D.

Ep. 140 – The Nature of Bingeing: How to Break Out of the Food-Prison with Dr. Glenn Livingston

JOOVV: For A Limited Time Go To joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

Listener Q&A: Lydia - IF and Palpitations

LMNT: For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase! Learn All About Electrolytes In Episode 237 - Our Interview With Robb Wolf!

AvalonX Magnesium 8: Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist, And Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

Simply Hydration: Magnesium-Charged Electrolyte Concentrate for Rapid Hydration

Listener Q&A: Sarah-Lynn - Positive side effects

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 282 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time, and get ready for The Intermittent Fasting Podcast.

Okay, friends, you can take chicken breasts off your grocery list. ButcherBox is offering our listeners an incredible deal that they have never offered before ever. Free chicken for a year. Yes, you can get two pounds of free-range organic chicken breasts for free for a year. I am not making this up. There is a reason we adore ButcherBox. They make it so, so easy to get healthy, delicious, humanely raised meat and sustainable seafood that you can trust. They deliver 100% grass-fed, grass-finished beef, free-range organic chicken, heritage-breed pork, that's really hard to find, by the way, and wild-caught sustainable and responsible seafood shipped directly to your door.

When you become a member, you're joining a community focused on doing what's better for everyone. That includes caring about the lives of animals, the livelihoods of farmers, treating our planet with respect, and enjoying deliciously better meals together. There is a lot of confusion out there when it comes to transparency regarding grazing practices, what is actually in our food, how animals are being treated. I did so much research on ButcherBox. You can actually check out my blog post all about it at melanieavalon.com/butcherbox. But I am so grateful for all of the information that I learned about their company. All of their beef is 100% grass fed and grass finished. That's really hard to find. They work personally with all the farmers to truly support the regenerative agriculture system. I also did an interview with Robb Wolf on my show, The Melanie Avalon Biohacking Podcast, all about the massive importance of supporting regenerative agriculture for the sustainability of not only ourselves, but the planet. This is so important to me. I'll put a link to that in the show notes.

The value is incredible. The average cost is actually less than $6 per meal. And it's so easy. Everything ships directly to your door. I am a huge steak lover. Every time I go to a restaurant, I usually order the steak. Oh, my goodness, the ButcherBox steaks are amazing. And their chicken is incredible, humanely raised, free range, organic and you can get it free for a year. Get two pounds of free-range organic chicken breasts for free in every order when you sign up at butcherbox.com/ifpodcast. That's two pounds of free-range organic chicken breasts for free in every order when you sign up at butcherbox.com/ifpodcast. Claim this deal at butcherbox.com/ifpodcast. If you've been wanting to try ButcherBox, now is the time. We will put all of this information in the show notes. 

And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense, because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting. It's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disruptors, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup maybe playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health, and they affect the health of our future generations. That's because, ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years. 

Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They have Countertime for anti-aging, Countermatch for normal skin, Countercontrol for acne and oily prone, and Counterstart for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life. And their makeup is amazing. Check on my Instagram to see what it looks like. Tina Fey even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready.

They have so many other products, deodorant, shampoo, and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20, to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. And you can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well. 

And lastly, if you're thinking of making clean beauty and safe skincare a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show.

Melanie Avalon: Hi, everybody and welcome. This is Episode number 282 of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hey, Melanie.

Melanie Avalon: How are you, Cynthia?

Cynthia Thurlow: I am doing well. I've got both my kids back in school.

Melanie Avalon: Oh, nice. More me time for you? 

Cynthia Thurlow: Well, at least they're not laying around the house. That's the one thing about teenagers is that they're like bears. They come out to eat, they come out to be taken places, and then they spend a lot of time in their rooms sleeping. And so, at least now during the day, my husband and I have a completely immaculate house, unlike when they're home. They're essentially savages. So, they're at least gone during the day. They're in school. They're being intellectually stimulated. It's all good.

Melanie Avalon: That makes sense. That's one thing I miss about being a teenager. It was okay to sleep like hours and hours and hours.

Cynthia Thurlow: It's interesting. My mom came to visit. My mom was very militant. We weren't allowed to sleep in, ever. And so, she was like, "You let your children sleep?" And I said, "Yes. Because they stay up late, and they need the sleep." [laughs] So, that's always the place I come from. I'm like, "As long as they get their work done, and they get their chores done, and they have good grades, I don't mind if they sleep," and it's really not an inconvenience to me. My husband and I go have half a day to ourselves before they wake up.

Melanie Avalon: That's the way my mom was growing up as well. That is something to be grateful for all the little things. Because that would have been miserable, if she had made us get up.

Cynthia Thurlow: Oh, my mom was just tough. I think because she was a healthcare professional, and was up early rounding, and seeing patients, and so, from her perspective, she had to be up, we should be up as well. [laughs] 

Melanie Avalon: Growing up, we would go to Sanibel Island in Florida every summer and I would always have a friend come with me. And it was funny, because I loved when I had the friend that had the same sleep schedule as me. We would both sleep until 2 PM. Because some of my friends were early morning birds. So, they would get up at 10 AM and have to wait for me for couple hours.

Cynthia Thurlow: So, this is not a new lifestyle.

Melanie Avalon: Oh, no, no. I think I've talked about this before on the show. I feel bad about it. I feel I should be a morning person. And every time I talk to my mom, my mom's like, "Melanie, you've always been a late-night person. You will always be a late-night person. Just accept it."

Cynthia Thurlow: We are very opposite.

Melanie Avalon: We are and I'm jealous.

Cynthia Thurlow: [laughs] No, I was thinking to myself, if we were ever in the same location at the same time, what would be the optimal hours we would be up at the same time? I'm like, "From 12 to eight." 

Melanie Avalon: Yeah. 12 is pushing it. [laughs] 1 to 8, 1 to 9. Is 9 pushing it for you?

Cynthia Thurlow: 9 is pushing it for me. Maybe 30, I'm generally like, "Okay, I want to go." I want to get on my PMF mat and start getting ready for bed.

Melanie Avalon: So funny. The socially acceptable hour that works for me to be like social is 7 or 8. Because most people are still like, they'll get drinks at 7 or dinner at 7. I know 8 pushes it for some people. But in any case, we have something exciting to share with listeners. Actually, two exciting things. One, would you like to share the winner of your giveaway?

Cynthia Thurlow: I would. The winner of our giveaway was Louise Sparks. So, we will be sending out your goodies within the next week. And I just wanted to take an opportunity to thank everyone for the wonderful, wonderful reviews that were left for the book. I'm so very grateful to be part of this community and very appreciative of everyone that submitted entries. 

Melanie Avalon: Yeah, it was really wonderful to read all of the reviews that, because I got to see them as well obviously being emailed in. It's just so wonderful how supportive, and kind, and just wonderful everybody can be. So, thank you. And what was the price? 

Cynthia Thurlow: We had very generous individuals, companies that donated products to the book launch. And so, there were some products from designs for health, some Redmond's products, all sorts of fun goodies. It was overwhelming how generous these companies were. And so, there were so much that was donated, we wanted to extend another option to share it with individuals that had read the book and loved it. So, thank you again, Louise Sparks.

Melanie Avalon: Awesome. Awesome, awesome. And then another exciting announcement. This is an opportunity to both learn very important things and also win very exciting things. So, okay, I'm so excited about this. I have a dear friend, R Blank. I've had him on The Melanie Avalon Biohacking Podcast. Cynthia, have you connected with R before?

Cynthia Thurlow: I have not definitely like on my radar, though.

Melanie Avalon: He's fabulous. He has a company called Shield Your Body and they are the global leader in laboratory tested EMF protection products. And okay, so, I am so passionate about this EMF situation. And it's interesting, because I feel people are skeptical of the health effects of EMF, but there have been-- Well, first of all, the World Health Organization lists EMF as a class to be carcinogen. So, this is not something that's woo-woo or not real. It's literally a carcinogen. And there's been thousands of high-quality peer reviewed scientific studies looking at EMF radiation from things like our cell phones and our air pods, and they found negative health effects like sleep disruptions, even infertility connections to Alzheimer's, obviously, connection to cancer. It's a really big deal. If you want to learn more about it, definitely check out my interview I did with R on the Melanie Avalon Biohacking Podcast. I'll put a link to it. 

The reason I really, really like what he's doing is, he is all about the science of everything and what is actually something to be concerned about what's not something to be concerned about, how can you actually mitigate it, and what is practical. He's not going to tell you to never have a cell phone or never use Bluetooth. Although, I think he personally, probably never uses Bluetooth. I don't want to put words in his mouth. But he's very good about making everything approachable and practical, which is why he has this company, Shield Your Body. And they have all these incredible products that will help protect you from EMF and they're tested, which is so, so key. But in any case, the exciting announcement. So, this episode airs September 12th. And on September 22nd, Shield Your Body is actually having EMF Radiation Safety Day. This is the fourth year that they've done it. It's actually on Faraday's birthday, so the guy who invented the Faraday cage. And the purpose of the event is just to spread awareness and help people learn more about the dangers of EMF exposure, how they can really shield themselves and protect their health, the health of themselves and their family. 

And so, basically, they offer tons of free, yes, free and easy ways to reduce your EMF exposure. And it actually according to them all comes down to two key rules. And no, I'm not going to tell you what those two key rules are. You have to get them for free. To get those two key rules and to be a part of Radiation Safety Day, because when you go to get all these free resources, you'll actually be entered into a giveaway to win a Shield Your Body canopy worth $2,000. So, that's just incredible. You can potentially win that canopy and in addition, they're going to be giving a lot of other prizes as well. So, you can go now to get the free resources and to enter to win. You will go to shieldyourbody.com/rsd. Again, that stands for Radiation Safety Day. And you can enter now all the way up until September 22nd. September 22nd is when they are going to do the raffle drawing. 

And in addition, while you're at Shield Your Body or just in general, if you would like to purchase any of their products, you can use the coupon code, MELANIEAVALON, and that will get you 15% off. I love their stuff. I'm actually right now using their wired headphones that do not have Bluetooth exposure. So, that's great. I really recommend their pad that goes underneath your laptop. If you are sitting with a laptop on your lap, again, there's studies showing that EMF exposure can affect fertility. So, it can be really, really important to have something like that protecting you from your laptop. They have bags, they have some apparel like a beanie, they have stuff for your kids. So, definitely, definitely check it out. Maybe you'll win that canopy.

Cynthia Thurlow: Ah, that sounds amazing.

Melanie Avalon: How do you feel about EMF exposure, Cynthia?

Cynthia Thurlow: Well, we had our house evaluated before we built it, the property and the geothermic forces underneath the house. And we have special material that was laid underneath our floors. And we have special-- [crosstalk] 

Melanie Avalon: I'm so jealous.

Cynthia Thurlow: [laughs] We didn't do a canopy in our bedroom. because I kept explaining to my colleague, I was like, "I am going to have teenage drivers. I can't be in an environment, where if there's an emergency and they're driving that I can't have my phone working. Maybe if they were a little younger, it'd be different." I would say, we probably did 50% of what was recommended. To do it fully 100% would have meant that there would have been absolutely no Wi-Fi at all upstairs in our bedrooms. And I was like, "That's not entirely realistic." We do shut down the Wi-Fi at night much to our kids' disappointment, especially because they are bears and they're up all night. But this house was definitely designed to be very conscientious. We have ethernet cables. All of our computers are wired into the wall.

Melanie Avalon: I am so happy right now to hear this. Same. I use ethernet. I'm on a wired computer right now. I turn off Wi-Fi at night. And we've talked, you know the EMF product that I'm creating, right? The issue that you just expressed, which I know is an issue for a lot of people. You need to have your phone on at night. So, what do you do about that? I'm actually working with R right now. We're working on a cobranded product. I am so excited. And it's going to be something to address that exactly. It's going to be something that you put on your nightstand, and you'll be able to put your phone in it, and it will shield you from your phone, but then you'll still be able to receive calls and you'll be able to charge your phone. I'm so excited. Stay tuned for that. But in the meantime, definitely go to that link, shieldyourbody.com/rsd. Enter to win the giveaway. Learn the two key rules to protect yourself and so much more.

Cynthia Thurlow: That's really important. And here's the one thing that I don't know, if listeners realize that some of us are much more sensitive to EMF. I'm a canary in a coal mine. And so, for me and my last house in Northern Virginia, there were so much external radiation and EMF that was coming into that house. As soon as we moved into the house, I stopped sleeping. And when Brian Hoyer came out and evaluated the house, he looked at me and he said, "You realize when EMF is this high, it upregulates cortisol and this is why you're not sleeping." And so, I just started to cry, because my husband thought I was nuts. But I'm trying to explain to him that there are those of us that are just much more sensitive to it and there are a lot of data centers in that part of Northern Virginia almost as much as what they have on Silicon Valley. And so, from my perspective, I think awareness is key, not to scare people, but just to bring awareness and then finding strategies that fit your lifestyle, I think is really important.

Melanie Avalon: Actually, when Gin was on the show, she had a whole experience, because she's always moving. She moved into a house and started getting a lot of sleep issues. And she thought it correlated to some other factors. And then when they were moving, she realized that her bedroom was right by the power grid and was thinking that that probably had something to do with it. It's so true. It affects people more than others. I actually also had Joseph Mercola on the Melanie Avalon Biohacking Podcast to talk about it as well. One of the really shocking things and this is just frustrating and it's maybe like the processed food industry or something. But the studies they use to set up safety regulations for cell phone use, the models don't match reality. The way they test for safety is not the way we would be using our phones. Normally, it's not the exposure we would be exposed to. It's very, I don't want to say rigged, but there's a way they keep continuing to make these devices that are having these health effects and it's really binging the rules and it's upsetting. But yes, there are things you can do. shieldyourbody.com/rsd. 

Cynthia Thurlow: Cool. 

Melanie Avalon: Shall we jump into some questions for today?

Cynthia Thurlow: Absolutely. This is a question from Erica. Subject is: "Eating and insulin levels." "I recently had a short conversation with Dr. Herring about insulin. Somebody on his Facebook page was talking about glucose and how if they have creamer in their coffee, their glucose doesn't rise after 30 minutes. I said, "If it doesn't rise, it's because insulin has been released and done its job." Dr. Herring then came in and said, "If insulin had done its job and the glucose reading would be lower." I asked, "Let's say you start with a fasting reading of 5 in just anything wouldn't a level go up to 7, insulin brings the reading back to a 5 or thereabouts. Are you saying that the levels should go even further down say, 2 or 3?" He didn't answer that question. Nearly three years living intermittent fasting now, thanks to you two for keeping me motivated via the podcast while I walk. I will never stop as it's just my normal now. 50 kilograms gone. Regards, Erica."

Melanie Avalon: And Erica is from Western Australia. 

Cynthia Thurlow: Perth is beautiful. 

Melanie Avalon: Oh, you've been there?

Cynthia Thurlow: I have not. But my boyfriend before my husband, who my husband has actually met, was from Perth and the photos, they had a farm, they were just beautiful. It's considered to be one of the most isolated areas of Australia in the world. But the photos were gorgeous. One day, I will get there.

Melanie Avalon: Oh, wow. I want to look up pictures. I love looking at pictures of places. That's so cool. Well, Erica, first of all, congrats on your success with the weight loss and thank you for your question. And so, I think this is good question because it taps into a lot of broad concepts that I think people get confused about or have questions about. So, I can speak briefly to it. Your blood sugar levels at any given time, there are so many factors that are affecting that. What's really crazy to think about-- It's actually mind blowing, if you actually think about it. The amount of blood sugar, so like, she's using millimoles to measure a blood sugar. But we in the US measure in the 90s or 80s, or one hundreds, that correlates to a very small amount of blood sugar. Like a teaspoon, I think is what I've heard. And so, it's really crazy to think that we will eat a bolus of carbs, like a massive amount of carbs. 

And when people who are diabetic can have issues. But even people are prediabetic, even that the levels might go high, but they never equal the amount of sugar that you're eating. The body does a really good job, even people who struggle with high blood sugar at keeping that regulated. Stepping back just to paint a broad picture, obviously, you can take in carbohydrates or sugar and that is a source of sugar entering your bloodstream. Or, your liver can release stored sugar or carbs in the form of glycogen into the bloodstream. Actually, fun fact, the majority of the blood sugar that you have in your bloodstream, including and diabetics is not from what you're eating. It's from the liver releasing it, which is just something interesting to think about. The third way would be the liver can actually make sugar, if it doesn't have sugar. Those are the three inputs. 

And then on the flip side like Erica was talking about, what's removing the sugar from the bloodstream is insulin, which is being regulated by the pancreas. And so, there's a lot of nuances here. And so, if you're taking in something that has carbs in it, presumably, that's going to lead to a blood sugar spike, which would go down, because you have insulin. In this case, she's talking about creamer in the coffee. And so, it's hard to know the actual creamer. So, this could be a creamer with carbs in it or it could be a creamer without carbs in it. If it had carbs in it and the glucose didn't rise, then yes, presumably, insulin put the carbs into storage and so they're not in the bloodstream. If the creamer real didn't have many carbs and it was fat-- And this is something that I think people get confused about as well. Fat is very easily stored. It doesn't necessarily require insulin to be stored. A reason that you could take in fat and not see a blood sugar rise and it's not because you put energy in your bloodstream and insulin got rid of it, it could be that insulin just wasn't even required. 

And the reason I'm saying all of this and sorry, if this is a lot of information, people are so unique. They'll do studies, where they have people basically getting a continuous infusion or injection of both insulin and glucose, and they can see how much insulin is required to keep the glucose level. Basically, how much insulin do you require to take in this blood sugar and not see any effect, any bump in your blood sugar level? And the reason that's important and the reason it relates to Erica's question is, that's going to be different. It's not like everybody requires x amount of insulin to take care of x amount of carbs. In this situation where the glucose didn't rise and she's asking, well, it should have dropped lower, it's completely an individual basis. Some people, they might release the perfect amount of insulin that they perfectly store it and it doesn't rise. Some people might release a little bit more insulin. And so, it actually drops lower than before, which would be the situation she was talking about the end. Or, if there weren't even carbs in it and it was just fat, which is a possibility. Insulin might not have been released at all, because in some wasn't required and there wasn't bump. That's a lot of information. Cynthia, thoughts? 

Cynthia Thurlow: No, I think you did a beautiful job. But the big takeaway is, fat has a much more negligible impact on blood sugar response. And so, that could explain why there hasn't been-- There's this negligible response. And so, I think it's important to delineate and discuss how blood sugar works, because I think it's oftentimes very misunderstood. I think people think about it in a very linear fashion, it's just one way. But there are multiple ways the body can impact blood sugar, insulin release, etc.

Melanie Avalon: I actually learned about something recently that I'm shocked. I didn't know about earlier. I'm very shocked. I used to always think that I had reactive hypoglycemia. I don't know if it's necessarily the example she gave, but it's the example she gave, where if you eat something, and then your body releases too much insulin, and your blood sugar drops lower than it was before, and you get feelings of having low blood sugar. I always used to assume that's what was going on. Maybe it was. But actually, I didn't know there was something called idiopathic postprandial syndrome and that's actually where it feels like reactive hypoglycemia. It feels like you ate and your blood sugar dropped. But if you were to actually test your blood sugar, it would be high. What's so cool about the reason that-- Well, I don't know if it's cool, but the reason that's happening there, like, theories about it, but it's likely because the body's trying so hard to control the blood sugar level that you get all of those hormonal feelings of anxiety, or shakiness, or fatigue, or adrenaline, and it's your body trying to control things rather than actually being low blood sugar. I'm just surprised. I didn't know that until a month ago. 

Cynthia Thurlow: Well, the word idiopathic really just means we don't understand why this happens. It'd really be a diagnosis of exclusion when they've rolled out everything else. But I think when we talk about reactive hypoglycemia, those are typically the people they get sweaty, they get diaphoretic, they get dizzy, they feel nauseous, they can get pretty symptomatic. And I think many years ago, when I was in school, we used to think of that as being very benign, but I look at it as it's sometimes that beginning stages of identifying that your cells are not well adapted to insulin.

Melanie Avalon: I just find it so interesting that you can have that exact experience and not have low blood sugar and that's like a thing. Got to love the word, 'idiopathic' for-- 

Cynthia Thurlow: Idiopathic means we don't understand why. That's basically what that means. People were like, "Oh, we'd--" [crosstalk] 

Melanie Avalon: But it makes it sound fancy. 

Cynthia Thurlow: Exactly. And I'm like, "It's really not." It means we don't understand why this happens and you're in this bucket.

Melanie Avalon: Love it. Love it, love it. Shall we answer a question from Catherine? 

Cynthia Thurlow: Absolutely. 

Melanie Avalon: This is from Catherine and the subject is: "IF weight and fat gain." And Catherine says, "Hi, I've read so many books and products you have recommended. I love this lifestyle and I love your books and podcasts. I've been wanting to write for a while and I kept telling myself, "I just needed to figure it out on my own." But as time goes by, my weight and fat keep creeping up, I thought I better seek your wise counsel. I began intermittent daily clean fasting, the first week of August 2019. I began my IF journey to maintain a weight loss of over one hundred pounds, but I've gained 20 pounds since starting IF. I'm 57 and 5'6.5". I walked 2.5 miles daily. I play pickleball." What is pickleball?

Cynthia Thurlow: I don't know. I think it's like a smaller bat.

Melanie Avalon: Pickleball according to Google is an indoor or outdoor racket paddle sport like you said. Like tennis with little, small bats. 

Cynthia Thurlow: [laughs] She's probably English. 

Melanie Avalon: Oh, yes. Okay. She plays pickleball or does it work out a few times a week. "Before if I was counting macros and every calorie I consumed or burnt daily to not regain. And I was successfully maintaining and still losing, but it was not fun at all, and I did not feel well. After dieting off and on, my entire adult life, I'm being overweight my entire adult life, I finally lost weight with the ideal protein diet. I think I heard Gin's recommendation to continue your current way of eating and add IF, but I did not follow that advice. Also, although I know it is not what you two would recommend, I just think I went overboard with eating what I had been denying for so long. I know that is not advised, but after limiting carbs or fat for so long, I just went for it. I love the simplicity of delaying and freedom of not denying but fear I have taken it too far." 

She said, "I usually fast for 19 to 20 hours and have a two to five-hour eating window. Typically, I have a shorter eating window on weekdays one to two hours and sometimes will lengthen it on weekends to three to five hours. I eat a healthy, typically paleo supper meal each day. I think my problem might be too much of a snack before and after that healthy meal. I started out between 125 to 130 pounds in August wearing a size four to six with very little fat on my bones and coming from a very restricted diet. I now weight 145 and I can see fat on my body. I can still wear the same jeans, but not all my clothes from 20 pounds ago. I feel great, I feel healthy, I look healthier. My hair is glowing. But I really liked the number 125 and I really liked seeing myself skinnier. if I'm completely honest, I looked pretty gone at 125. I do look healthier now. I hear all the stories of weight loss and feel, I should have at least been able to maintain my weight with IF. 

Honestly, I could probably be happy with 135. I do not want to continue gaining weight. I'm wondering if I need to deny sugar and chocolate indefinitely as it is probably a trigger for me. Should I start counting the calories of my snack or dessert? Is there anything you can recommend for me? I will not go back to dieting. I am IF for life. Thank you so much for your books and podcasts. I have learned so much from you. I so look forward to your direction and thank you in advance."

Cynthia Thurlow: Well, Catherine, thank you for your question and congratulations on the progress you've made. A lot of what I hear in this question is, you really like one number, but you feel healthier, better, your hair looks healthier at a different weight. And herein lies a lot of the problem in the weight loss industry. We get very fixated on numbers. And I'm speaking to you as a clinician that at a minimum, I would get some basic lab worked on, so that you can see where your triglycerides are, and your HDL, and look at your fasting insulin, your glucose, your A1C really get a sense of your thyroid and sex hormones to see really where you are. 125 pounds is pretty thin for 5'7" female. 

And you yourself mentioned that you've looked gaunt. From my perspective, it's really stepping back and objectively saying, what is driving the focus on that number? Because it sounds to me that you actually feel better at a different number. I would say, the other thing and this is a resounding theme for me is that if you're only eating within a very short window, are you eating enough food? Because your body could be perceiving that you are not enough food that you're starving and it's going to hold on to every single calorie and morsel of food. Really making sure that your meals are structured focused on protein, as well as non-starchy vegetables. You may be craving chocolate and sweets, because you're not getting enough food. And so, I really think you need to objectively and honestly look at, are you eating enough food in your feeding window? You may not be. And checking in with your primary care provider, your internist, your GYN to get some baseline labs, I think is a really important first step. And then also giving yourself grace. 

There are so much focus in our society on weight numbers, instead of focusing on health and what allows you to go out and play your sports, and to walk, and doing all the things you're doing it. It doesn't sound like for you that you want to track macros and that's okay. I would really try to be deliberate about getting enough protein in your diet and we usually focus in on a hundred grams a day. Hundred grams per pound of ideal body weight. And really focused in on healthy fats and non-starchy vegetables and also, that mindset shift. I know, both Melanie and I have interviewed Dr. Glenn talking a lot about our relationship with food. I think that those interviews would be super helpful to hear his perspective and he talks about the inner pig, not that we're a pig, but the inner pig in our brain that's telling us to behave a certain way. 

And make sure you're getting enough sleep. And make sure that you have great relationships with loved ones. And making sure that you feel satisfied in your personal life, I think is certainly a very, very important part of this. But the concerns that come up for me are, are you eating enough? Having this fixation on a number that may not be a healthy number for you to be at. I have had so many female patients that will say, "I want to weigh what I waited 18" and yet, this is 20, 30 years later, and it's woefully not realistic for them to weigh. What they did at 18 years old, when they probably weren't nourishing themselves or probably not getting enough sleep, etc. Melanie, what are your thoughts?

Melanie Avalon: First of all, I love all of that that you said, and I agree. I want to clear up one little thing. She says that she had heard Gin's recommendations about continuing your current way of eating and adding IF, so not changing the way you're eating. What's interesting about Catherine situation is, so, Gin's perspective on that it's normally not Catherine situation. It's normally people who are coming from a standard American diet and Gin says, "Start IF rather than cleaning up your diet at the same time." Whereas Catherine situation, she was on a really restrictive diet. And so, she did "change" when she started IF, because instead of staying on the restrictive diet, she started eating much more freely, which the two clarifications there is that I think-- I don't want to put words in Gin's mouth, but I think Gin would be more on board with that concept, actually. 

And then, two, I think people can do it either way, but I actually don't have a problem with people starting IF and making dietary changes at the same time. I actually think it's really great. I think if people want to like start, especially if coming from a standard American diet and they want to make a healthy, whole foods type choices at the same time as they start IF, I think that's great. I just wanted to clarify on that. I think everything that Cynthia said that that lower weights that Catherine was at might not necessarily be a sustainable weight, if you want to maintain certain health and energy related goals at the same time. So, really what you have to ask yourself, because I'm goal-- Am I goal agnostic? I'm goal agnostic for other people. I personally believe that our goal should be health and wellness and energy and vitality. But also, I believe that people can have whatever goals they want. It's their body. You can pursue what you want to have in your body. And for some people, if they want to be a thinner weight that requires dietary restriction, you can do that. It might not be a healthy approach to life and it might be hard to maintain. Because Catherine experienced that. She was calorie counting, she was macro counting, she wasn't enjoying her life, she didn't feel as good. So, that might just be what is required to have been at that weight. And so, you just have to ask yourself, "Is that what you want?" 

And what I am wondering, though is, I think there actually is a lot of room. Stepping back, I know you did actually, physically gain weight because you say with an exclamation point, how you can see the fat on your body. But I also do wonder if making this change from having been calorie restricted and being in a calorie deficit to sounds like you're just going and eating all the things. I wonder if there's a level of inflammation that came along with that style of eating, so there might be a happy medium. This is just an idea. But there might be a happy medium that doesn't actually require calorie counting, it doesn't require macro counting, it doesn't require restriction, where you're just cleaning up those food choices that you are making. I think that might be a place to start rather than trying to go the restriction route. 

Cynthia was talking about the importance of a high protein diet and the green vegetables. And so, maybe having a mindset shift, where we What are the healthiest foods you can put in your body in your eating window, what is the healthiest way you can approach your snack and your dessert? If you have them, can you possibly have other versions? Can you not have the snack or can you have other versions of the dessert and snack that might be more fulfilling or healthier for your body? I would just maybe approach it more from a health mindset with a few choices rather than a restriction mindset. Because I think it's completely 100% possible for you to actually have all the goals, which would be the energy, and the skin, and feeling amazing in your body from that perspective, and also, being at a weight that makes you happy, and it doesn't necessarily require restriction. Any thoughts to that?

Cynthia Thurlow: I do fervently believe a lot of it's a reframe. So, really thinking about your relationship, not only with your body, but with food as well can be very, very helpful, for sure. 

Melanie Avalon: Also, I love that you brought up Glenn Livingston. He is honestly one of my favorite people on the planet. His book, again, it is called Never Binge Again, which is a little bit of a misleading title, because it's not just for people who are struggling with binge eating disorder, but it's really wonderful for that mindset shift and reframing how you are seeing food, your cravings, your wants, your desires. I find it very helpful.

Cynthia Thurlow: That's a great book. Actually, I think twice this week already, I suggested that episode to women in different groups. 

Melanie Avalon: I love that. I love that. 

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Melanie Avalon: All right, shall we go on to our next question? 

Cynthia Thurlow: Absolutely. 

Melanie Avalon: I'm excited for this question, because it's a Cynthia question. This comes from Lydia and the subject is: "IF and palpitations." And Lydia says, "Hello, I'm Lydia. And recently, July 11th to be exact began doing intermittent fasting. I purchased Delay, Don't Deny and listen to the podcast regularly, as well as join the Facebook groups. Well, I soon began to have heart palpitations and I have read that maybe I was dehydrated. I upped my water intake, I added Himalayan salt occasionally, but I was really having a bad time with the palpitations. They especially occurred when I lay down for whatever reason. I'll be seeing a cardiologist soon after getting an electrocardiogram and after wearing a Holter monitor for 48 hours. But after I stopped doing the clean fasting and I stopped longer fast, the palpitations are mostly gone. So, is it possibly dehydration after all? Have you heard of others having this issue? I was so happy to have lost 10 pounds by August 14th. But now, I'm slowly gaining back since I haven't been clean fasting. By the way, my starting weight was 167 and I'm about 5'6". Now, I'm back to 161 after getting to 157 by August 14th." Thank you, Lydia.

Cynthia Thurlow: Well, Lydia, this is my wheelhouse. The listeners know that my whole background as an NP was in ER Med and cardiology. And the one thing that I know a lot about are palpitations, ones that are benign, but annoying and dehydration. And I would absolutely agree that if you are going too fast, you need electrolytes. And yes, Himalayan sea salt is great, if you're salting your meals. But you actually need a more comprehensive product and that one that is going to provide potassium, and magnesium, and sodium, and chloride. And so, anytime anyone is fasting, especially in summer, it's really, really important that you're replacing those electrolytes. And it more than likely, I would imagine that the palpitations are probably precipitated by low magnesium. And this is more often than not the electrolyte in particular that I see most people are not keeping optimal levels of. And really the blood tests that you want to ask for when you see the cardiologist and any cardiologists will order this as a red blood cell magnesium. It's much more accurate. But also doing a comprehensive metabolic panel. It sounds like they're doing quite a big workup if they're doing a Holter as well as an EKG. 

If you're seeing an association of fasting correlated with the palpitations and now that you are stopped the clean fasting and stop longer fast, and the palpitations are almost gone, I think, oftentimes, we'll say correlation is not causation, but this is clearly a relationship that sounds it is directly related to the dehydration. You're probably experiencing by not replacing the electrolytes in a fasted state. One thing I teach people when they're fasting for the first time is that electrolytes are critically important, especially, if perhaps at that time, you lowered your carbohydrate intake. We know when you tend to be lower carb, you have release of glycogen, which is stored sugar and you'll actually urinate out more electrolytes including sodium. And so, it's very, very important that you're replacing that. And there's lots of clean options. I have a product called Simply Hydration. There's LMNT and many other options that are out there. 

The other thing is you mentioned that your weight fluctuated from 161 to 157 pounds. It is not at all uncommon depending on what we're eating and drinking that our weight could fluctuate by three to five pounds. And so, I don't know what age you are, but that can happen around our menstrual cycles, it could happen if we had a lot more carbohydrates. And so, I wouldn't get too concerned about four pounds. It's always over the period of time. There's a colleague of mine that always talks about there's the Hell No Way. When you get to a point where you're like, "Okay, this is five pounds over where I generally am average wise and then it's time to ratchet in on the cleaner eating." I would absolutely follow up with your cardiologist. They sound like they're doing a really nice job. I would focus on comprehensive electrolyte replacement and especially, in a fasted state. More hydration, more electrolytes, and recognizing that there is that interrelationship. And it's probably related to low magnesium and I'm actually setting Melanie up, so that she can talk about magnesium. 

Melanie Avalon: I love that. Well, first of all, for listeners who might not be familiar, Cynthia, what is your background in cardiology?

Cynthia Thurlow: Well, it's interesting. I did general cardiology, but then when I transitioned into to predominantly doing office setting, I worked with a lot of our electrophysiologist, who are specialized cardiologists that do defibrillator, and pacemakers, and deal with arrhythmias. When I tell you that I know magnesium backwards and forwards, more often than not even in the benign arrhythmias, it was magnesium that was precipitating episodes. And more often than not in the lethal arrhythmias, things that originate from the ventricles, which are the bottom chambers of the heart. It was magnesium that was driving some of those symptoms. When I tell you that I know magnesium well, I've gotten very creative over the years with magnesium replacement. We could certainly if Melanie, if you want to we can talk about other ways to replace magnesium either with transdermal applications, or soaking our legs, or taking products by mouth. All can be very, very helpful when getting our magnesium levels back up.

Melanie Avalon: Yes. Well, first of all, I just love that you have that background and that knowledge. I will put in a plug for LMNT. Cynthia mentioned them. But we do have an offer for them. There are full-spectrum electrolyte supplements. So, not just magnesium. It's magnesium, potassium.

Cynthia Thurlow: Sodium chloride.

Melanie Avalon: Dah. Sodium. So, you can go to drinklmnt.com/ifpodcast and we have an offer there. I believe the offer right now should be to get free electrolytes at that link. Definitely check that out. And then, yes, it is so, so exciting that Cynthia is on board and on the same page as me about the importance of magnesium. So many people are deficient in magnesium. I'm actually not for taking all the vitamins all the time. I think it should be very nuanced and specific to the individual. And that, when possible, we should try to get our nutrients from food. That said, it's really hard to get adequate magnesium levels today. Our soils are depleted. It's been estimated that in the past one hundred years, the soil levels of the magnesium have gone down by 90%, which is crazy. And then on top of that, that's just the actual levels of magnesium. That doesn't account for the fact that pesticides and glyphosate in the soil actually chelate magnesium. So, a lot of that magnesium isn't even available to the body to be used in its proper form. And then on top of that, it is potentially toxic, because it's attached to a pesticide. 

The fact that most people are deficient is no surprise. And so, like Cynthia said, there's lots of ways that you can boost and raise magnesium levels. I recently released my Magnesium 8 by AvalonX and I formulated it to honestly be the best magnesium on the market. I promise, it is the best, because I wanted to make the best. It is eight forms of magnesium and their most bioavailable forms. But it comes with methylated B6 to help with absorption, not the non-methylated form, which is often used in supplements. And then it has manganese, because magnesium can often displace manganese. And then it's in a glass bottle, because I am not about plastics leaching into our bodies in the environment, which by the way, Cynthia, I just booked a guest. I'm really excited about. Matt Simon, he's the head editor at WIRED and he has a book coming out in 2022. He has some other books, but his book coming out in 2022 is about the effects of microplastics and the environment. I'm so excited, because I think that's a really big problem. So, I'm really excited to read this book and learn about that. 

Oh, and this was crazy. One of my best friends from college ever worked at WIRED. I emailed him. I was like, "I don't know how many people are on staff at WIRED, but do you know my friend?" And he's like, "Oh, yeah, we sit next to each other in the office." It's such a small world. So, all that to say, you can get my Magnesium 8, that is at avalonx.us. The coupon code, MELANIEAVALON will get you 10% off. I think we will have launched subscriptions by the time this comes out. If you get a subscription for that, you can get actually 15% off. The other ways of getting magnesium would be like transdermal.

Cynthia Thurlow: And I like a product called Ancient Minerals that we will link up. You can spray that into two cupped hands and rub it on your, I usually say, trunk. Like upper arms, legs, trunk. And if your skin tends to be sensitive, you want to pick the sensitive skin formulation. But you can leave that on for 20 minutes and then rinse off. That's super efficacious.

Melanie Avalon: So good resources there. Hopefully, that helps, Lydia. Do we have time for one more question?

Cynthia Thurlow: Sure. Our next question is from Sarah. Subject is: "positive side effects." "I've been doing IF since the first of the year as an experiment just to see how it worked for me. Your podcast has been a valuable resource for me and I'm grateful for all your tips. I don't need to lose any weight or gain energy, but I was tired of constantly thinking about when and what I was eating to get maximum nutrition benefits. I felt I was either eating or preparing to eat all the time. Needless to say, IF has changed that with a shorter afternoon window usually 3 PM to 8 PM. I have always eaten a pescatarian diet with a balance of nutrients. I do enjoy at least a small, processed food snack a day like Chex Mix or Cheez-It and I've not changed my diet at all. 

I am so much less stressed about food, and I think I can finally achieve the rest and digest state. One of the positive side effects that I've noticed in myself that I don't think I have heard you discuss is the change to my bowel movements and the decrease in gas. I often had gas in the evenings and carried Gas-X in my purse at all times. I have not needed to take it on the last two months. Also, sorry, if this is TMI, but my bowel movements were previously very soft. Since intermittent fasting, I noticed my bowel movements are now more solid and easier to clean. Just wondering, if this is truly a result of intermittent fasting and why the change. Thanks, and keep up the good work." Casey.

Melanie Avalon: Thank you so much for your question and we're very excited for you that you've experienced so many wonderful effects with intermittent fasting. Earlier, Cynthia was using the phrase "correlation, not causation and how it's hard to know." But I would say, it's very likely that if the only thing you perceived as having changed was IF and then you had this substantial change in your bowel movements, then it's probably related to IF or changes from IF that led to this. I mean, it's a good problem to have. So, I'm happy that we're not trying to find the problem and solve it. But there's so many different things that could be going on for why you might experience better bowel movements. By not eating constantly, it gives our GI tract. It allows for the natural peristalsis of the intestine, and it allows things to be moving. So, it can create a better synchronicity and rhythm to your system, where your digestive system has time to rest to clean out with those cleansing waves and not have things build up that are creating gas. It also might be--

You talked about how now finally when you're eating, you feel you're in the rest and digest state, so the parasympathetic state. That is so, so important for properly digesting our food, for creating stomach acid to digest our food, enzymes. The fact that you are just likely digesting your food better, it could be a huge reason that you're not having gas anymore, you're having better, more well-formed bowel movements. It's just helping your body process food better. And then the effects on the gut microbiome, so, there's a lot of effects that could be happening there. It's possible that this change with the fasting is actually supporting a more favorable gut population. There have been studies on fasting finding favorable effects on the gut microbiome. So, it's possible that you've had changes there. Cynthia, thoughts?

Cynthia Thurlow: I would echo your sentiments. And I think a lot about the migrating motor complex. And so, in our digestive system, we really do need four to five hours between meals to allow this sweet sweeper of the GI tract to be able to do its magic. And there's so much good research talking about the gut microbiome and the benefits of eating less frequently. And is it any surprise that your digestive processes is out now in a position, where it can properly package up and get rid of waste? And so, not at all surprised to hear that your bowel movements are much more solid. We use that Bristol stool scale. Melanie, have you seen that before?

Melanie Avalon: Have I? You're talking to like the-- [laughs] 

Cynthia Thurlow: We aim for the for. That's what we're working towards. And so, it just shows that your stool is-- there's enough time for your body to break down absorb nutrients, get rid of what doesn't belong, you're not dehydrated. I think our stool is really one of many indicators of our health. So, bravo and excited that you've had seen so many benefits so quickly.

Melanie Avalon: I probably shouldn't share this. I should probably envision thousands of people listening before I say this. It's funny, because they'll do things. I don't know who 'they' is. You'll see things where people say, "Eat something really pigmented, so you can figure out how long your transit time is," like do a beat test or like a blueberry test. 

Cynthia Thurlow: We used to do corn.

Melanie Avalon: Okay, corn. And it's funny. Whenever I see that I'm like, "Wait, doesn't everybody always monitor that, like, monitoring that 24/7?"

Cynthia Thurlow: You're hilarious. No, it's interesting. There's a program that I teach in the fall called RESTART. I think it's week two. I actually have them bring corn to class, and they ingest two tablespoons of corn, and then they let me know how long it is before they see it in their stool.

Melanie Avalon: I had an intake form with a doctor and he's like, "We're going to do this." I was like, "I do that every day. I can already tell you that." 

Cynthia Thurlow: You are like, I'm an ideal patient.

Melanie Avalon: I already know the answer to that question. All right. Well, this has been absolutely wonderful. A few things for listeners before we go. We will put links to everything that we talked about in the show notes. Those will be at ifpodcast.com/episode282. A reminder to everybody to definitely go to shieldyourbody.com/rsd for Radiation Safety Day. That's where you can learn the two key rules to help protect yourself from EMF exposure for free and get entered to win a EMF blocking bed canopy worth $2,000, as well as a lot of other prizes. All for free. Lots of resources. That's shieldyourbody.com/rsd And again, the coupon code, MELANIEAVALON will get you 15% off, if you would like to purchase anything from Shield Your Body. 

And there will be a full transcript in the show notes. You can definitely check that out. And then lastly, if you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. And you can follow us on Instagram. We are @ifpodcast. I am @melanieavalon, and Cynthia is @cynthia_thurlow_. Well, this has been absolutely wonderful. Cynthia and I will talk to you next week. 

Cynthia Thurlow: Sounds good. 

Melanie Avalon: Bye. 

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and recomposed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Sep 04

Episode 281: Myth Busting, Fasting Research, Fat Burning, Inflammatory Markers, Media Spin On Studies, Early Vs. Late Night Eating, And More!

Intermittent Fasting

Welcome to Episode 281 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

LMNT: For Fasting Or Low-Carb Diets Electrolytes Are Key For Relieving Hunger, Cramps, Headaches, Tiredness, And Dizziness. With No Sugar, Artificial Ingredients, Coloring, And Only 2 Grams Of Carbs Per Packet, Try LMNT For Complete And Total Hydration. For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase!

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To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

LMNT: For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase! Learn All About Electrolytes In Episode 237 - Our Interview With Robb Wolf!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist, And Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

Oura Referral Link!

Get $30 Off A CGM At Nutrisense.Io/Ifpodcast With The Code IFPODCAST!

Listener Q&A: Knowles - Myth Busting3

Paleo Mom Podcast Episode 386: Intermittent Fasting

Paleo Mom Podcast Episode 381: Is Breakfast the Most Important Meal of the Day?

Intermittent Fasting: Secret to Weight Loss or Dangerous Fad? 

Is Breakfast The Most Important Meal of the Day? New Science Has Answers!

Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans  

Short-term modified alternate-day fasting: a novel dietary strategy for weight loss and cardioprotection in obese adults

Alternate day fasting for weight loss in normal weight and overweight subjects: a randomized controlled trial

FEALS: Go To feals.com/ifpodcast To Become A Member And Get 50% Off Your First Order, With Free Shipping!

Impact of breakfast skipping compared with dinner skipping on regulation of energy balance and metabolic risk

Early Time-Restricted Feeding Improves 24-Hour Glucose Levels and Affects Markers of the Circadian Clock, Aging, and Autophagy in Humans

Is advice for breakfast consumption justified? Results from a short-term dietary and metabolic experiment in young healthy men

The effectiveness of breakfast recommendations on weight loss: a randomized controlled trial 

Effect of skipping breakfast on subsequent energy intake

The causal role of breakfast in energy balance and health: a randomized controlled trial in lean adults  

Early Vs Late-Night Eating: Contradictions, Confusions, And Clarity

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 281 of the Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat, with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time and get ready for The Intermittent Fasting Podcast.

[intro ends]

Hi, friends, I'm about to tell you how you can get my favorite electrolytes for free. Yes, completely free. And the feedback we have received about LMNT Electrolyte from our audience is overwhelming. You guys love LMNT. And I'm so excited because our new offer allows new and returning customers to get free LMNT, and on top of that they're super popular grapefruit flavor is back. If you've been having issues with intermittent fasting, electrolytes may just be the thing that you need. And/or have you heard of something called the Keto Flu? Here's the thing. The keto flu is not actually a condition. Keto flu, just refers to a bundle of symptoms. Headaches, fatigue, muscle cramps and insomnia that people experience in the early stages of keto dieting. Here's what's going on When you eat a low-carb diet, your insulin levels drop. Low insulin, in turn lowers the production of the hormone aldosterone. 

Now aldosterone is made in the kidneys and it helps you retain sodium. Low aldosterone on a keto diet makes you lose sodium at a rapid rate. Even if you are consciously consuming electrolytes, you might not be getting enough. In particular, you need electrolytes, especially sodium and potassium in order for nerve impulses to properly fire. Electrolytes can easily be depleted while intermittent fasting. Robb Wolf, who as you guys know is my hero in the holistic health world, worked with the guys at Ketogains to get the exact formulation for electrolyte supplements, to formulate LMNT Recharge, so you can maintain ketosis and feel your best. LMNT Recharge has no sugar, no coloring, no artificial ingredients, no junk. They're used by three Navy SEALs teams, they are the official hydration partner to Team USA weightlifting, they're used by multiple NFL teams, and so much more. 

We have an incredible offer just for our listeners. You can get a free LMNT sample pack that includes all eight flavors. Citrus, watermelon, orange, raspberry, mango chili, lemon, habanero, chocolate, and raw unflavored. And the raw unflavored, by the way is clean fast friendly. You can try them all completely free when you make a purchase at our link, drinklmnt.com/ifpodcast. You can get this offer as a first time and as a returning element customer. I know there are a lot of returning LMNT customers. The feedback I hear from you guys loving LMNT is amazing. LMNT offers no questions asked about refunds on all orders. You won't even have to send it back. And this offer is exclusively available only through VIP LMNT partners. You won't find this offer publicly anywhere else. So, again, the link is drinklmnt.com/ifpodcast. And we'll put all this information in the show notes. And one more thing before we jump in. 

Are you fast and clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense, because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain, and it's not your food and it's not fasting? It's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things, like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup maybe playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That's because ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking. And the effects last for years. 

Conventional lipstick, for example, often test high in lead, and the half-life of lead is up to 30 years. That means, when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so you can truly feel good about what you put on. And, friends, these products really, really work. They are incredible. 

They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life. And their makeup is amazing. Check on my Instagram to see what it looks like. Tina Fey, even wore all Beautycounter makeup when she hosted the Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. 

Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well. 

And lastly, if you're thinking of making Clean Beauty and Safe Skincare, a part of your future, like we have, we definitely recommend becoming a band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show.

Hi, everybody, and welcome. This is episode number 281 of the Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hello, there, my friend.

Melanie Avalon: How are you today, Cynthia? It's been a while?

Cynthia Thurlow: Yeah, I'm doing well, because it's like hard for me to say this, but my kids are all going to be in high school as of next week.

Melanie Avalon: Oh, wow.

Cynthia Thurlow: They're going back to school. Two different schools, but, yeah, we're in that mode of back-to-school shopping and supply purchases and new computers. And it's just hard to believe the summer is effectively over for them.

Melanie Avalon: So, this is actually a mind-blowing moment for me. So, when I was in high school, I was like the only person-- I brought a laptop to class, like nobody had laptops. Do all the kids use laptops now?

Cynthia Thurlow: Oh, it's interesting. My youngest is going to a magnet high school and they require laptops, so we had to purchase one for him. And my other son who goes to the local public high school, they are supplied with Chromebooks, which is like a laptop. And that's what they utilize. But I'm actually giving my oldest son my Apple because I'm going to get a new laptop. And he'll have that he can use for school.

But, yeah, it depends on where you are in school, like the STEM focus magnet schools and the school where my younger son is going, they require them, because they want them to be able to work from anywhere, not from the perspective of 24/7, like a lot of adults do. But they allow them to have a lot of freedom during the course of their day. And they like them tethered, not tethered to an outlet that they can just get up and use their laptop anywhere. Outside, inside, in the lounges, etc.

Melanie Avalon: It's just so funny to think about how things have changed, because literally I was the only person and I brought a laptop to-- I had to get permission to do it. And they were fine. But it was because I was like it's so much more efficient for me to type my notes during a lecture than write them because I ended up retyping them anyways.

Cynthia Thurlow: I'll really date myself here. When I went to college, there were three of us in college at the same time. Back then computers were super expensive, like prohibitively expensive. I had a word processor. I'm sure there are probably some listeners who remember what that was. But I had a word processor, not even a computer. I didn't have a computer until I went to graduate school. I think it was even like a hand me down like iMac that my mom had. So, yeah, past facts.

Melanie Avalon: Things have been changing.

Cynthia Thurlow: Absolutely.

Melanie Avalon: I have an interesting experience to share with listeners. How long have you had an Oura ring, Cynthia?

Cynthia Thurlow: A little more than a year, might be about a year and a half.

Melanie Avalon: Okay, I've had mine about two years. I can verify on it that I got sick for the first-time last week, with the exception of COVID. I don't really count COVID. I haven't gotten sick in at least two years. I don't remember getting sick, like before my Oura ring. I think it's probably been about three years of getting sick non-COVID. I had a fever and chills. And it's so funny, I was so excited-- not excited, but that night that it hit me, I was like, I can't wait to wake up and look at my Oura ring and see if it knows that I'm sick. I did. And my score was awful, and it knew, that's when I was able to look back through the data and see if I'd had a fever at all in the past two years. But what's interesting is, the very next day, I was completely back to normal HRV wise, readiness score wise, and I've actually been better since before getting sick. But I have been so tired. It's like I'm experiencing the COVID fatigue that people talk about. But I didn't have COVID because I tested, I didn't have COVID this time around. Some things I've noticed during this experience, to share with listeners is one, for people who take my Serrapeptase, I'm blown away because my memories of being sick are congestion and runny nose and not being able to breathe. Interestingly, I haven't had barely any of that. I know it's all there, but the Serrapeptase just keeps me so clear. So, I've been so, so grateful for that.

And then secondly, I mean, it's a little bit disconcerting that I'm still really tired. Normally I've been canceling everything, calls, going out with friends. Normally I do business calls when I'm running errands, and I haven't been doing any of those because I've been like I can't run an errand and talk on the phone at the same time. I've been scratching my head about what to do. I was talking with my friend James Clement, who wrote a book called The Switch. And actually, Morgan Levine talks about him in her book as well, who I interviewed and who you are interviewing in an upcoming episode. She's amazing. I've been talking to him about what to do. And he keeps saying that I said high dose NMN. Cynthia, do you take NR or NMN?

Cynthia Thurlow: I don't. Admittedly, it'll be fully transparent. I don't feel like I know enough about the better brands for those products. I think that's really what it comes down to, because I know there's a lot of smoke and mirrors in the supplement industry. For full disclosure, I usually just lean on Melanie's recommendations, if it's something I don't know a lot about. I'm like, "What would Melanie do?

Melanie Avalon: Oh, it's so funny. Well, especially with NR and NMN. For listeners who are not familiar, there's something called NAD in our body. And Peter Attia, did you listen to this episode, he recently did an episode with a guest expert in NAD?

Cynthia Thurlow: It's on my list. But it's like I really have to set aside the time like I've been listening to the Huberman and Attia podcasts. And since it's like more than two hours, it's been two gym workouts, and I'm still not done with it.

Melanie Avalon: We talked about this. So, you listen to podcasts while working out?

Cynthia Thurlow: I do, or books. It depends on my mood. But lately, I've been getting back to podcasting.

Melanie Avalon: I have to do music if I'm at the gym. I listen at night, usually to podcasts. But he did do a recent dive into NAD. In any case, NAD is how I keep talking about magnesium being the master mineral in the body. NAD is basically the master coenzyme in the body, literally involved in everything. It's an all of the cells. And there are some theories out there and talking to James, this is his theory that especially with COVID, that post COVID fatigue and long COVID, might be due to depleted NAD in the body. And we see with age that NAD actually goes down as well. A lot of scientists also think a lot of aging effects are due to depleted NAD. So, keeping your NAD topped up is super important.

But you can't take NAD as a supplement. But you can take the precursors, which are NMN and NR and there's been so much debate about which version is better. And like you just said, Cynthia, especially with NAD and NR, a lot of just sketchiness in that industry. I've been historically taking both and experimenting. And I think I can announce this, I announced before that we were going to make NMN at AvalonX. And then we couldn't because it's in the gray zone with the FDA. But things are changing. I probably will be releasing an NMN upcoming sort of soon, which I am so thrilled about. So, needless to say, I was talking with James, and his direct quote to me was, "Do not underestimate the effect of high dosing NMN."

What he actually does, he has a lab; he made his name by doing work on the blood work of super centenarians. And now he does a lot of anti-aging lab work. And he's literally testing NMN and NED and stuff like that in his lab all the time. He's been helping me figure out a dosing schedule. I started high dosing the NMN that I'm taking right now two nights ago. And I actually did start feeling a little bit better. And today's the first day I feel, like this is not wearing me out right now to talk. And I took so much NMN last night. And I think it's so important that I actually over the next four days, I said, you can't take NED as a supplement, but you can as an IV, or as an intramuscular injection. So right after this, I'm going to go get an NAD injection. And then I have two IVs scheduled and then another injection. I mean, I can't keep being sick this long. I'm like not down with this. That was a lot. But basically, listeners, I think NAD is so, so important.

Stay tuned, because, hopefully, I'll be releasing my own NMN soon. For updates on that, definitely go on the email list. That's at avalonx.us/emaillist, avalonx.us is also where the Serrapeptase is and the magnesium and the coupon code MELANIEAVALON gets you 10% off. But I just share all of that because I mean, I love these supplements, but getting sick has made me realize, it's when you're sick that you realize what's important to you. So that was a long spiel, but you got sick sort of recently, right, with laryngitis?

Cynthia Thurlow: When I came back from Europe, I was convinced I must have had COVID because I spent two days in bed. And then I was like, "If I didn't have COVID, I must have flu." And I kept coming up negative for both. But I started a whole regimen of high dose vitamin A, vitamin D, a slew of other things that thankfully, my physician friends called in for me and I felt better, usually within a day and a half. But my Oura ring, the day before I started feeling poorly was already telling me something was brewing and it stayed abnormal for like four or five days. And then it went back to normal. I don't know what I had. But I do think for all of us we lean into the narrative that, "Oh, it has to be COVID." And I just think you can get an apparent virus.

Melanie Avalon: There are other things. Sorry, I'm so glad you said that, didn't mean to interrupt, because so many people I've talked to they're like, "Oh, it's probably COVID. I'm like, "Well, I had COVID. I tested this time around, it was negative. And they're like, "Oh, but it's probably still COVID. I'm like, "Guys, there are other viruses besides COVID."

Cynthia Thurlow: And, unfortunately, that's the mentality is, "Oh, if you get sick now, you can't just have like a common cold virus."

Melanie Avalon: What happens all the other coronaviruses, like it's COVID19 because there are a lot of other coronaviruses.

Cynthia Thurlow: Right. We flew from Budapest to Amsterdam, ran through an airport, I'm not kidding, ran, sprinted to our flight to Boston, Boston to our home. And I was like, "Who knows what I got exposed to?" Even though you know, travel to me is generally pretty enjoyable. But your immune function can be impacted by a lot of things. And certainly six hours ahead, the net impact of time differences and things you get exposed to while you're traveling and the stress of traveling. Let's be honest, it's not stress free. I'm mentally gearing up for three trips I have back-to-back in September and early October. And I was telling my husband, in between the LA and Scottsdale trip, I think I'm home for two days. And I'm like, "Oh, I'm going to be like really hunkered down as an introvert in between those big trips. So, yeah, there's a lot that goes into it. And not every viral illness is the pandemic bug, it could very well be just a latent, benign summer virus that people used to never think twice about.

Melanie Avalon: I'm so glad you said that, because it's like everything's COVID now.

Cynthia Thurlow: Right. And it doesn't have to be. In between my trip and then I had a week at home and then I went to a business trip in Austin and I felt like I did tell every single person I saw that I tested four times for COVID only because I wanted to be able to demonstrate I really didn't have it. Not because I thought I had it but it's now become an expectation that people are hypersensitive, hyperaware to what is now an endemic virus. And the joke is amongst my ER medicine friends, the only people that don't have COVID are the ones who have been tested. Meaning, you probably have had it; you may just have had a really mild case, you may not have tested. Anyway, I don't want to dive down that rabbit hole. But the point is not every viral illness is COVID, or flu for that matter.

Melanie Avalon: Yeah, exactly. So definitely been an experience. And I'm really excited to see again, so the high dose NMN is helping, but I'm really excited to see over these next four days with the NED, if that just gets rid of the fatigue, although I've heard that the IV can be a very unpleasant experience. We'll see if I make it through that. Oh, and last thing, I had a call with Oura ring yesterday. Listeners, I might have a code soon, finally. So stay tuned for that. People ask me for a code like every day in my life.

Cynthia Thurlow: I actually have an Oura ring code.

Melanie Avalon: With your name?

Cynthia Thurlow: Why did they sign--? It's people get money off and they get six months of free service?

Melanie Avalon: What? Like a CYNTHIATHURLOW code?

Cynthia Thurlow: I don't even know. I mean, we'll include it in the show notes. But they made it just for me.

Melanie Avalon: Whoa, I have been trying so hard. I had the call yesterday. And they were like, "Well, we'll fix that for you." Treasure that, they do not give those out easily. My listeners know I've been trying.

Cynthia Thurlow: Well, because I tagged them constantly. I'm always like showing my data and then I talk about Oura ring probably as much as you do. And I tell everyone, it's like my favorite form of technology that really has been helpful for me determining what I need to do to-- for me, it's really been-- my REM sleep was always good. My deep sleep was the one that needed work. And so, I'm constantly working on that, constantly.

Melanie Avalon: Yeah, wow. The show notes will be at ifpodcast.com/episode281.

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Melanie Avalon: All right. Shall we jump into everything for today?

Cynthia Thurlow: Absolutely. So, this is from Knowles. "Hi, Melanie and Cynthia. I'm a 65-year-old woman 110 pounds, and I've been fasting since August of 2021. I'm doing it for the health benefits. When I read something like the issues raised by Dr. Sarah Ballantyne below. I don't know what to think. She sounds legit, and so do the studies. I'm doing fasting for health reasons, so need to know the scoop. Please address this soon. Thanks, and I love your show. I hope you can shed more lighter on this and other recent studies. Thanks for all the information." And here's what she says, "Myth busting intermittent fasting." "Most studies in humans have shown that intermittent fasting doesn't provide any additional benefit compared to other diets, with metabolic and cardiovascular benefits attributable solely to the weight loss during the study. In addition, the most common way of IF'ing by skipping breakfast results in higher inflammatory responses, and increases in measured insulin resistance after lunch. Studies also show that routinely skipping breakfast increases the risk of type two diabetes by a shocking 55%. Increases the risk of cardiovascular disease by 21%. And increases all-cause mortality by 32%. All in all, there's far more science pointing to the benefits of breakfast, and eating dinner on the early side to support better sleep."

Melanie Avalon: And then she lists out two different blog posts. One is called Intermittent Fasting Secret to Weight Loss or Dangerous Fad. One is called, Is breakfast most important meal of the day. New Science has answers." And then there are links to two of her podcast episodes. Episode 386, Intermittent Fasting and episode 381, "Is breakfast the most important meal of the day?" And that is on her, what podcast is that?

Cynthia Thurlow: The Paleo Mom.

Melanie Avalon: I have so many thoughts here. Okay, well, to start things off, when her podcast episode 381 published, I breakfast most important meal of the day came out, or it might have been one of those that she links, people were asking about it in my Facebook group. And she actually co-host The Paleo View. Or at least she used to with my good friends, Stacy Toth. This came up in the group, I listened to the podcast episode, and I did a deep dive into what she talked about. And so, I'm going to talk about all that here. And all of this is not to argue her, try to discredit or disprove what Dr. Ballantyne is saying, I just think she brings up a lot of good topics. And I learned a lot listening and diving into what she was referring to. And then I also did a deep, deep dive into one of the specific studies that she talks about because her blog post Is breakfast the most important meal of the day, new science has answers, that is an analysis of a 2017 study called Impact of breakfast skipping compared to a dinner skipping on regulation of energy balance and metabolic risk.

I was reading that study, and it was actually a really fascinating study. I'd love to talk about it anyways. So, I'm just going to talk about all that and then people going to-- we can see where we go from there. So maybe I'll start with that blog post about the 2017 study. So basically, in one of her emails, I'm going to read what she says about the study, and then I'll read what the study actually said. She says that a 2017 study used a randomized crossover design to evaluate skipping breakfast versus skipping dinner, compared to the standard three meals per day. Time restricted feeding, either skipping breakfast or skipping dinner resulted in slightly higher energy expenditure for the day. And while skipping breakfast, but not skipping dinner increased fat oxidation. It came at the expense of higher inflammatory responses, a whopping 54% increase in the postprandial HOMA index, meaning increased insulin resistance, and higher blood sugar and insulin levels after lunch. 

And then she says, "A recent study of how intermittent fasting affects insulin sensitivity showed that the feeding window didn't really matter. What did matter was having the first meal before 8:30 AM." That's Dr. Ballantyne's words. The actual study, what they did was they looked at-- well, first of all, a problem I have with the study, it was very short. So, people basically did like a day of skipping dinner and a control day, and a day of skipping breakfast with a washout period. And it was only a day of each of these. And I think that right there is a problem because it doesn't give people time to acclimate to whatever IF pattern they're doing, because we know it can take the hormones a little bit of time just sorts of regulate to a new rhythm. So that's just a little bit problematic, starting thing off. But that said, there were a lot of good findings in the study.

The participants ate the same similar macronutrients throughout the days. One of the biggest things, the biggest takeaway, at least for me, and Dr. Sarah Ballantyne mentioned this, was those that skipped breakfast, so when they ate dinner, they actually burned more fat. So, it's a huge takeaway from the study is that the participants who skipped breakfast, so basically, they were having a leader eating window, they not only did they burn more fat than those that skipped dinner, they burned fat when the other group was burning carbs. So basically, the people who ate all throughout the day, were burning carbs more. And it was the exact same for the people who skipped dinner. So, the people who were eating earlier burn the same amount of carbs, essentially, as those that were eating throughout the day, compared to those that skipped breakfast and only ate dinner. It's like flipped. They basically burn fat all day, not all day, but they burned a lot of fat. So, they were fat burning for the majority of the day compared to the other group that wasn't. And I just think that that is huge. 

What's interesting is, she mentioned how the HOMA-IR at lunch was worse for those that skipped breakfast. And what HOMA-IR can tell us is, it's like she mentioned a measure of insulin and glucose that can give us a picture of insulin resistance. So, it was worse for those who skipped breakfast after lunch.

One of the problems about the setup is they didn't test HOMA-IR all throughout the day, they only tested one data point, which will-- it was a few different times, but it was basically amount of time surrounding the lunch meal. And what's important to note about that is that's testing the HOMA-IR at a different timeline for the two setups. So, like if you really wanted to make it controlled, I think you would have needed to have tested HOMA-IR, so that it would match the amount of time into the eating window for both of the two arms, the breakfast skippers and the dinner skippers. I don't know if that's quite making sense. But basically, just like looking at one snapshot, I don't think gives a full picture of the entirety of everything, especially when fasting insulin sensitivity 24-hour glycemia, and glucose variability, and 24-hour insulin secretion were all similar for all of them. So basically, all of that was really similar. But when they looked at this one time point, they found a difference. I don't know that that's actually a full picture of what's going on.

And then something fascinating from the study. And I find it interesting that Dr. Ballantyne didn't mention this at all when she talks about the study, even though later in her email, because what we read was from her email, later, in her email, she talks about other studies looking at the role of cortisol and how fasting might have a negative effect on people's cortisol levels and people's stress levels. This study actually found that those who skipped breakfast had a better stress response. While the cortisol and the 24-hour cortisol profile was similar between all the groups. Those that skipped breakfast, I will quote, "It says overall HRV," so we were talking earlier about Oura ring. HRV is your heart rate variability, and it can be used as a marker of your body's stress levels, and higher HRV is basically a better stress response. The study says that overall HRV, heart rate variability, was higher on the breakfast skipping day than on the dinner skipping day. It says that the findings of the study argue against a higher sympathetic tone and suggest improved autonomic regulation with breakfast skipping. 

The sympathetic part of the nervous system is basically like our fight or flight version of our nervous system. The parasympathetic is the more relaxing, calming part of our nervous system. This study found that for those who skipped breakfast, they had a better stress response. They're less of the sympathetic, more the parasympathetic, and improved autonomic regulation. They found that skipping breakfast was better for their stress levels, which is the-- Well, Dr. Ballantyne didn't even mention that from the study, and then it contradicts what she says a little bit later about another study on cortisol. The study makes this case and Dr. Ballantyne makes this case that maybe breakfast skipping is leading to metabolic inflexibility because of that HOMA-IR score. But what's confusing to me, and I'll be curious to hear your thoughts on this, Cynthia, it's like why would we assume metabolic inflexibility based on this one HOMA-IR score taken at one point, when overall, when we look at the entire day, those that skipped breakfast were burning more fat? 

It just doesn't make sense to me. If they're burning more fat for a substantial amount of time, clearly it's a different message than metabolic inflexibility. I find it interesting that that's a conclusion that's drawn. Interestingly, what the study concluded their final, final conclusion was that-- and this is also interesting, because you can make a lot of conclusions from this study. And this is what I want listeners to understand the way these studies are handled, because we'll talk about how there'll be a study, and then it gets interpreted in the media or interpreted by bloggers, or doctors or scientists or influencers, and you can put whatever spin on it you want. But even the study itself, they often put whatever spin on it they want. They focus on what they want to focus on. So, everything I just told you, you could have concluded so many things. You could have concluded skipping breakfast is better for your stress levels, you could have concluded, skipping dinner decreases fat burning. There's a lot of things you could have concluded. But what did they concluded a causal role of breakfast skipping for the development of obesity is not supported by the present data. They basically concluded a negative. Rather than saying, skipping breakfast leads to more fat burning, they concluded that skipping breakfast does not encourage obesity. And it's a small thing, but it just really shows, I think, what the aim can be with certain studies.

So, that was my analysis of that study, honestly reading it, I was like, this makes me want to skip breakfast. Like you'll burn more fat--Oh, I left out the inflammatory response potential. I am so sorry. There was another aspect of this study, where they looked at the immune response. And Dr. Ballantyne talks about this. And it's interesting about here what they did is they looked at the-- again, look, they looked around lunch, and they looked at the blood of the participants, and they didn't look at the inflammatory response of the blood, right then. It wasn't like they looked at them eating the meal and then they looked for levels of inflammatory markers like IL-6. So, they put into the blood either LPS, which is lipopolysaccharide, which is basically a byproduct of gut bacteria that our body registers as a toxin, or they put in hemagglutinin, which is a glycoprotein that causes an immune response in red blood cells. It's kind of like the whole lectin type thing. And they saw how the blood reacted.

So, they didn't look at the inflammatory response of the blood right then. They took the blood, they put in something that the immune system that would react to, and then they tested to see how the blood reacted. And they did find that those who skipped breakfast, had a more exaggerated inflammatory response when they put in basically, a toxin or something that aggravates the blood into the blood. And I don't know enough about immunology to really speak more length on that. Other than to say that I'm not really sure what's going on there and I'm not really sure what the implications are. They concluded that it was maybe because the participants who skipped breakfast were burning more fat when they ate, so they had higher levels of fat in their blood, and that that could exacerbate the immune response to LPS and hemagglutinin. I don't know. Again, it's a thing where I would set it up differently where I would have that response tested so that it's being tested on the early eaters and the late eaters equivalently based on how long they've been fasted, or how long they've been eating, that was in there as well. That was so much, and I also have thoughts about her other blog posts. But I'm going to stop talking for a little bit. Cynthia, do have thoughts?

Cynthia Thurlow: I think this really speaks to what happens in the media and many other well intended, I have to believe, this is a well-intended email and blog posts that were written. It's under the presumption that most people don't know how to read research. And it's under the presumption that we aren't going to question what she believes was the key takeaways from this research that was done. And this is why Melanie and I are very committed to really taking the time to thoughtfully look through the research and to be able to say, "This actually isn't the case. If you really look at the research, you really look at the variables, there are so many things that impact, the HPA, the hypothalamus pituitary axis, the stress response in the body, a lot of that could have absolutely nothing to do with meal timing. I feel fervently and strongly that this is one of many reasons why there's so much fear mongering about fasting. And really, we would not be here as a species if it wasn't something that was very aligned with ancestral health perspectives. But when you start layering in the stresses of a modern-day lifestyle, like many of us experience, stress going to work, and stress with kids, and stress with getting sick and all these other things adding in additional layers of stress on top of fasting may make it a less than ideal circumstantial choice. But I don't think that the key tenets from that email and from that study were extrapolated in a way that's particularly helpful. In fact, I think it contributes to the fear mongering mantra and message that we see all over social media, from health influencers, etc. 

And Melanie did a really, really nice job kind of diving into the research, and looking at what it did actually really show. Even when I do little IG lives or I do really short videos, I always say, "Look at the research, was it statistically significant? What was the endpoint they were looking for?" So really getting at least somewhat knowledgeable about what to be looking for and to question. And really, that's what science is doing is, is forcing us to question and to consider, do we need to look at this differently? But it has always been my experience that fasting-- and when we look at the bulk of the population here in the United States is one example. It's anywhere from 8% to 9% of the population is metabolically healthy. So hello, that's most everyone is not metabolically healthy, eating less often is not going to hurt you. I think that's the big thing to stress, like, the big takeaway is, who benefits from us eating all day long? What industry benefits? 

The other thing that I like to look at, Melanie, I'm not sure if you actually looked at this. But I'm always like, "Who funded this study? Who funded the research that we're looking at?" To see if there's any biases, because I think that can also be very, very impactful. But this is trying to throw the baby out with the bathwater, one of those old sayings that my grandmother used to say that, you really have to dig a bit deeper and understand that even people with research backgrounds can actually cherry pick data. It happens super commonly. This is one of many reasons why I think it's important to get savvy or at least familiarized with basic research tenets, and to also, is it something that is outside the norm of how you would normally think about, something like be humble enough to say, "No, maybe there's something here I haven't looked at." But I looked at this as well, and I have to agree with Melanie that, there's nothing to support, the key takeaways that Dr. Ballantyne has in that article or in those emails. I think it's unfortunate, because many years ago, I think I did actually follow her, but I got to a point where I had to unsubscribe. But I think in a lot of levels, I appreciate when our listeners bring these things to our attention, so that we can address them proactively and say, sometimes there's going to be a time when we might say, "Hey, we may need to rethink our thought process on a particular area," versus saying, "I still felt pretty confident that eating less frequently, and not eating large boluses of food throughout the day is ultimately going to improve metabolic flexibility, is going to keep our insulin levels lower, is going to improve those HOMA-IR scores that you were referring to." It just goes to show that even well-meaning people can put out cherry pick data, which is when I first read this that was my visceral response.

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It's really interesting, because I understand that that HOMA-IR when they measured it around lunch seemed worse on the breakfast skippers. But I don't know how you draw the conclusion that they're becoming metabolically inflexible when they started burning fat, and the control group didn't and the dinner skippers didn’t. And then interestingly so, I mentioned that it concluded that skipping breakfast was better for your stress. So later on, Dr. Ballantyne talks about how IF might negatively affect cortisol levels, two references to 2019 study where she says, early time restricted feeding altered the diet neural patterns and cortisol, morning cortisol was elevated and evening cortisol was lowered. And she says this implies that this is not an appropriate dietary strategy for anyone with unmanaged chronic stress. So, this really confuses me, because last time I checked, the cortisol pattern that we wanted was higher cortisol-- like the natural cortisol rhythm is higher cortisol in the morning, lower at night. The study found that, that fasting led to higher cortisol in the morning and lower at night. I don't know. Do you have thoughts on that? That's what I think we would want to see.

Cynthia Thurlow: Yeah. The circadian biology, if you look, you actually get a spike in cortisol about 30 minutes after awakening, and you want to see it ebb and flow throughout the day. But it follows a very commonly, and a healthy person follows a common distribution and higher in the morning, it ebbs and flows throughout the afternoon, and then it's lower in the evening. And you wouldn’t want your cortisol to be the opposite. If it was low in the morning, you would be dragging, you can barely get out of bed. And if it's high at night, then you're wide awake and you can't fall asleep and you can't relax. Circadian biology is something that I have really gotten to know very well. And so that doesn't seem at all aligned with the way things should ideally be. Meaning, we want to see a vibrant cortisol response in the morning. It's what gets us up out of bed, it suppresses melatonin, gets us moving. And then we want cortisol to be lower in the evening when we're getting ready to go to bed, some of us earlier than later. And we want to see a nice vibrant response with melatonin. So that doesn't make any sense to me. And maybe there's something I'm missing.

Melanie Avalon: I've read it so many times. I remember when I heard it in the podcast, and she said that and I was so confused, because I was like, "Well, what do you want to see then?" I just don't understand.

Cynthia Thurlow: Well, sometimes I think some of these individuals, and maybe it's not even Dr. Ballantyne, who wrote that maybe it was an assistant or someone on her team. But the assumption is made is that most people don't know basic science. And if you understand, like very basic science, you would say, "Hmm, that doesn't make sense to me because the normal distribution of cortisol and I look at these labs almost every day," that's what you want to see. When it's dysregulated, when you've got hypothalamus pituitary dysregulation, meaning your brain and your pituitary gland and your cortisol, or the adrenal axis, so it's HPA axis. When that axis is disrupted, that's when you'll see an abnormal distribution of cortisol throughout the day into the evening. And so, I have to agree with you.

Although it's interesting when you think about stress, like if someone is going through a divorce, they're having like they've lost their job, or they're going through a contentious move, that might be the time not to add more stress to the body, even if it's a beneficial hermetic stress. But in most instances people can take their foot off the accelerator, and maybe they're doing 12 hours of digestive rest, but I still don't understand how you could say that it's not beneficial, honestly. We're looking at the degree of metabolic ill health we have here in the United States, it's almost-- I actually am getting more bolder on social media, I was saying on Twitter, something along the lines, like, if you're a health care provider, and you're not advising your patients to check their blood sugar's or to recommend a glucometer or CGM, and I'm getting a little off on a tangent, we're really doing them a disservice. And so, I think the same thing, if you're not telling every single patient to go 12 hours without eating, that's criminal, absolutely criminal.

Melanie Avalon: That ties in a little bit to one of the podcast episodes that was referenced. She did bring up a lot of topics, which I think are good topics for discussion. There are things we will be talking about anyways. The one that that made me think of was, she believes the benefits of intermittent fasting are often basically all due to calorie restriction. And that the fasting is harder than calorie restriction. And I have a lot of thoughts surrounding that. Even if the benefits because I know this is an age-old debate, or as long as it can be an age-old debate, which is as long as IF has been a colloquial idea. But even if the benefits of IF are just due to calorie restriction, which I do not believe they are, I believe they activate similar pathways as calorie restriction. But that you can get the benefits without calorie restriction. Even if the benefits are just due to calorie restriction, and people are just accidentally eating less by doing IF, I think it's very hard to get people to do calorie restriction normally, so if people can easily, "unintentionally" do calorie restriction because they're fasting, I see that as a win. I don't have any issue with that.

Cynthia Thurlow: Melanie, I think it's also this very reductionistic thinking, when people say, "Oh, the only benefits are that you've reduced your calories." And I'm like "No, that's actually not correct." And it's an opportunity to really help educate people that there's so much more to the benefits of fasting that people are unaware of. I think people come to it because they want to change body composition or lose weight. But if it were simply about the calories, then we wouldn't have all this other vibrant research that suggests that there's a lot of benefits that maybe aren't apparent, reduction in inflammation, autophagy upregulation, all these other things that people sometimes lose sight of.

I think it also speaks to the fact that we have conditioned our patients to believe that they need to be eating all day long, and eating snacks and many meals and the reality situation is. Even people who are thin have plenty of stored food in their bodies, stored fat that they can access if they're fat adapted. And there's a lot to unpack here. And I'm trying to restrain myself, because I could go off on many different tangents about the fear mongering and the cherry picking of data that seems to be really prevalent, much more so now than ever before.

Melanie Avalon: That's why I thought about this part of it because how you're saying that doctors should be telling people to go a certain amount of time without eating. But there's often this response of it requires calorie restriction or it's not sustainable. And it's just better to eat all day. I don't see that. In that podcast, she talks about how-- she speaks specifically about ADF, alternate day fasting, and how it's more difficult than calorie restriction. So, interestingly, ideally for me, it wouldn't be more difficult than calorie restriction, but I do find ADF, it does not appeal to me, I think it'd be too difficult for me, not something that I would like. That said, there are so many studies that have found that not to be the case. So, I'll put links in the show notes. But for example, one called alternate day fasting improves physiological and molecular markers of aging and healthy nonobese humans. That one they saw no dropouts in six months for people doing ADF. They saw two drop outs in two months for people who were not doing ADF compared to one drop out in three months of ADF.

And then there's one called short-term modified alternate-day fasting, a novel dietary strategy for weight loss and cardio protection and obese adults. They found that the compliance on ADF was very high, 86%. And it was even higher, because often in studies, they'll do like an enforced part of it, where they basically give the people the meals, and then there's like the self-done version. And they actually found that people were more compliant when they were doing it themselves, which is pretty cool. And then there's one called alternate day fasting for weight loss and normal weight and overweight subjects, a randomized control trial. And they found that people doing ADF had adherence rates of 98%, and that their hunger did not change. And the longer they did ADF, they felt more satisfied and more-full. ADF is probably hard for a lot of people. Like I said, I don't want to do it. But there's been a lot of studies where people find it very easy to adhere to. I wouldn't make a blanket statement about it being something that's not practical or not implementable.

And then she does have a lot of takeaways about breakfast studies. And this claim that the majority of studies show the benefits of breakfast, and I have dived deep into breakfast studies, especially when I was writing What When Wine. What Cynthia was talking about earlier with funding, this is where it is shocking the amount of studies that are funded by the breakfast cereal industry. It's just shocking. And there's actually a 2013 meta-analysis. Up until that point, their conclusion was "a majority of pro breakfast studies feature bias interpretations, misleading language and proper citations and inappropriate terminology." So, basically, there's a huge bias in the literature.

On top of that, there's the healthy user bias. That's the idea that the people who skip breakfast are often the type of people that are engaging in other healthy habits, because we've been told for so long that breakfast is the most important meal of the day. Sorry, I said people who skip breakfast, people who eat breakfast tend to smoke less, drink less, eat more fiber, eat more micronutrients, be physically active, that can be a misleading thing for all the studies. And then if you actually look at the studies on skipping breakfast, that's just not what it shows. A lot of the studies show that skipping breakfast, people do not overcompensate, they usually end up eating less throughout the day overall, when they skip breakfast, they don't make up for skipping an entire meal, even if they eat like a little bit more at lunch. I'll put a link in the show notes to my blog post that I did on early versus late night eating. And that was more in the context of fasting. But when I actually looked into the literature on everything, and I tried to be as unbiased as possible, and I walked away thinking that the best time to eat, it's not what I do, by the way. It's not like late at night, like I do. But it did seem to be between like 4:00 to 7:00. Basically, later afternoon to early evening, while the sun is still up. I tried my hardest to be as unbiased as possible. And I looked at so many studies.

Cynthia Thurlow: Well, I think you're also a unicorn. I lovingly say that I think that it works for you. You're metabolically flexible, you are insulin sensitive, but the average metabolically inflexible individual would probably struggle with-- like when I think about late night eating, when it's dark outside, it's not aligned with the way our bodies are designed to thrive. For the average person in that subsect, it could be detrimental if it was something they did all the time. But this is when bio-individuality really rules. And this is certainly a degree of experimentation. I know when I used to work crazy shifts in the hospital like 11:00 AM to 11:00 PM. More often than not even would get a dinner break in the evening, and you would just eat because if you didn't eat then you weren't going to be able to eat later. But I think it's really leaning into what works for each one of us.

Then the research is helpful. That's one thing I want to respond as clinician. Research is helpful to guide suggestions and recommendations, but ultimately, it's the clinician or the N-of-1 or the patient or the individual really determining what works for them and is in their best interest. I think that's really important. If we get hung up on, and I'm just speaking in very general terms, research is helpful. Research confirms many things that we do clinically. Research can also just leave us with more questions like, "Oh, we need more research done on this area." We know that women there's not enough research done on women as one example, because there have been a lot of fears about subjecting women to research that are of childbearing, ages, for many concerns about the potential teratogenic effects. Meaning, anything that could potentially happened to their fertility or an unborn child. But I think there's now a push and a demand for not just being exclusive and looking just at men or menopausal women, but looking at everyone to get a really good representation of what the research holds for. I mean, that's my feeling. I'm always looking at it objectively and saying, yes, research is helpful, it can confirm what we need, or it can cause us to look at different variables that are impacting fasting or metabolic health. But I always think it's important to determine for each one of us what is working or what is not working,

Melanie Avalon: I cannot agree more. I think bio-individuality is so, so key. I am a late-night person. According to Dr. Breus, I'm a dolphin, and I have cortisol spikes probably late at night. Eating late at night really brings down that cortisol for me. It's just really interesting because I honestly think if we could get rid of all of the biases of society, and we didn't have this narrative about breakfast, and I think if people just objectively sat down and looked at the hormonal profiles of people naturally, like, what would they conclude? I don't think you would conclude that you should eat breakfast, because once you wake up, cortisol spikes, adrenaline spikes, you have hormones that are releasing fuel from your body. It's not a time where your body is asking for fuel. Ghrelin, the hunger hormone raises a little bit later, not right when you wake up. I did a deep dive into the hormonal profile, it was really, really interesting. But then again, there are people that love breakfast, and that's what their body wants. And that's where, like you said, bio-individuality is key.

Cynthia Thurlow: Absolutely.

Melanie Avalon: I feel this was the anti-fearmongering episode. I'm also glad you brought that up about the role of women in studies. One another reason I loved interviewing Morgan Levine, I find that it's the female scientists that are the ones talking about this. She talks about in her book, some of the problems with anti-aging research and how women often historically haven't been as included in the studies. There's definitely a need for more women in studies.

Cynthia Thurlow: Well, it's interesting, even when I was writing my book, and I've got so many references, they're housed on my website, because it would have taken up on a 20 or 30 pages in the book, there just isn't enough. We can't compare ourselves to lab animals. And we can't compare ourselves to primates. We really do need good researchers really looking at all these variables. And to be honest, anecdotally, I'm starting to see emerging trends that are coming up. Actually, I'm doing a webinar for the DUTCH company. So, this is a Precision Analytical DUTCH test, is a test that I use quite frequently in, especially in programs like Holistic Blueprint, which we're enrolling for in September, and they'd asked me to do a very slanted discussion on metabolic health and fasting and nutrition, which, of course, I'm happy to do. And I identified for them, I'm starting to see this triad of women, they are over-fasting, over-restricting, over-exercising, and those are the women I worry about the most in terms of adding in more fasting, it's the extremes that we as women don't weather quite as much.

It's not to suggest women can't work hard and work out hard, and doesn't mean they cannot fast. But if we're over-restricting everything in our diet, and we're anti-carb, we're not eating enough protein, we're eating the wrong types of fats, we're exercising seven days a week during CrossFit. And sorry to pick on CrossFit, I'm just trying to think of a very intense form of exercise without recovery. And then on top of that you're doing two 24 hour fasts a week, guess what? That's not going to balance your hormones, that's not going to put you in an advantageous position. As we are asking and demanding for more research, we're going to see some interesting results that come out of that. And I think Ben Bikman was recently talking about suppression of mTOR and how that can impact, I hope I'm not miss speaking. I think he was talking about ovarian follicle health. You really start to think about the fact of why I always say like, if you're a healthy woman under the age of 35, don't over-restrict your food and don't over fast. That's the kind of research we need to see, what's the net impact of hormetic stress on different stages of life. Not just women's still at peak fertile year, but in perimenopause and menopause, I think that would be really interesting and certainly very telling. I'm glad that there are researchers like Dr. Levine who are advocating for women and certainly doing the research. They're in the thick of things and hopeful that that will yield more helpful information to guide recommendations and clinical decision making, N-of-1 decision making moving forward.

Melanie Avalon: I'm glad there are people like you, like clinicians, working with patients and looking at all of the research and advocating, so strongly for women and all of this. So, thank you.

Cynthia Thurlow: Absolutely.

Melanie Avalon: Well, so that was a deep dive.

Cynthia Thurlow: That was a one question IF Podcast episode, but we will be back next week with lots of questions.

Melanie Avalon: Yes, I knew that was going to happen. When I was reading, it took me a long time to read through the study, I was like, "This is going to be a long episode." For listeners, there will be a full transcript, which I know will be very helpful because that was a deep dive. And links to everything that we talked about, because we talked about a lot of things in the show notes, those are at ifpodcast.com/episode281. You can submit your own questions by directly emailing questions@ifpodcast.com. Or, you can go to ifpodcast.com and you could submit questions there. Lastly, you can follow us on Instagram, we are @ifpodcast. I am @melanieavalon, Cynthia is @cynthia_thurlow_. I think that is all the things.

Cynthia Thurlow: Great deep dive into that question. And thank you, listeners, keep them coming. It's always enjoyable when Melanie and I dive into the research and look at different ways of making observations and certainly helping you, wade through a lot of misinformation that's out there, and there are certainly plenty of it.

Melanie Avalon: Yes. All right. Wow, this was absolutely wonderful, and I will talk to you next week.

Cynthia Thurlow: Sounds good.

Melanie Avalon: Bye.

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice, and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs and original theme composed by Leland Cox, and recomposed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Aug 28

Episode 280: Pet Foods, Fibroids, Estrogen Dominance, IF After Pregnancy, Protein & Autophagy, Macros, Hashimoto’s, Oral Microbiome, Mouthwash, And More!

Intermittent Fasting

Welcome to Episode 280 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

BUTCHERBOX: Grass-Fed Beef, Organic Chicken, Heritage Pork, Wild-Caught Seafood: Nutrient-Rich, Raised Sustainably The Way Nature Intended, And Shipped Straight To Your Door! For A Limited Time Go To Butcherbox.com/ifpodcast And Get Free BACON For LIFE plus $100 off your first 5 boxes!

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AvalonX Magnesium 8: Get Melanie’s Broad Spectrum Complex Featuring 8 Forms Of Magnesium, To Support Stress, Muscle Recovery, Cardiovascular Health, GI Motility, Blood Sugar Control, Mood, Sleep, And More! Tested For Purity & Potency. No Toxic Fillers. Glass Bottle. Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist, And Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get Free BACON For LIFE Plus $100 Off Your First 5 Boxes!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

The Forever Dog: A New Science Blueprint for Raising Exceptionally Healthy and Happy Companions

Intermittent Fasting Masterclass with cynthia Thurlow

IF45 Coaching Certification Program

Wholistic Blueprint class

BON CHARGE: Go To boncharge.com And Use Coupon Code IFPODCAST To Save 15%.

Listener Q&A: Niki - Fibroids

Listener Q&A: Lucy - My story and getting started again

never binge again™: How Thousands of People Have Stopped Overeating and Binge Eating - and Stuck to the Diet of Their Choice! (By Reprogramming Themselves to Think Differently About Food.)

The Melanie Avalon biohacking Podcast Episode #45: Glenn Livingston, Ph. D.

Listener Q&A: Niki - Protein & Autophagy

Listener Q&A: Dana - More Protein

AVALONX MAGNESIUM: Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist, And Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

Listener Q&A: Angela - IF And Gargling Salt Water And/Or Mouthwash

go to melanieavalon.com/bristle and the coupon code MELANIEAVALON will get you 15% off sitewide

Ep. 153 – Fix Your Mouth/Fix Your Health: Reversing Tooth Decay Naturally with Trina Felber

Listener Q&A: Barbara - Over 70 Women And IF

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health :care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 280 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, nurse practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time and get ready for The Intermittent Fasting Podcast.

[intro ends]

Hi friends, I'm about to tell you how you can get sugar-free, nitrate-free, heritage breed bacon for life. Plus, up to $100 off. Yes, free bacon for life. Plus, up to $100 off. We are so honored to be sponsored by ButcherBox. They make it so, so easy to get high quality, humanely raised meat that you can trust. They deliver 100% grass-fed, grass-finished beef, free range organic chicken, heritage breed pork, that's really hard to find, by the way, and wild caught sustainable and responsible seafood shipped directly to your door. When you become a member, you're joining a community focused on doing what's better for everyone. That includes caring about the lives of animals, the livelihoods of farmers, treating our planet with respect, and enjoying deliciously better meals together. There is a lot of confusion out there when it comes to transparency regarding grazing practices, what is actually in our food, how animals are being treated. I did so much research on ButcherBox. You can actually check out my blog post all about it at melanieavalon.com/butcherbox. But I am so grateful for all of the information that I learned about their company. 

All of their beef is 100% grass-fed and grass-finished, that's really hard to find. And they work personally with all the farmers to truly support the regenerative agriculture system. I also did an interview with Robb Wolf on my show, The Melanie Avalon Biohacking Podcast. All about the massive importance of supporting regenerative agriculture for the sustainability of not only ourselves but the planet. This is so important to me. I'll put a link to that in the show notes. If you recently saw a documentary on Netflix called Seaspiracy, you might be a little bit nervous about eating seafood. Now I understand why ButcherBox makes it so, so clear and important about how they work with the seafood industry. Everything is checked for transparency, for quality and for sustainable raising practices. You want their seafood. The value is incredible. The average cost is actually less than $6 per meal. And it's so easy, everything ships directly to your door. I am a huge steak lover. Every time I go to a restaurant, I usually order the steak. Oh, my goodness, the ButcherBox steaks are amazing.

I remember the first time I had one and I just thought this is honestly one of the best steaks I've ever had in my entire life. On top of that, did you know that the fatty acid profile of grass-fed, grass-finished steaks is much healthier for you than conventional steaks, and their bacon, for example is from pastured pork, and sugar and nitrate free. How hard is that to find? And I'm super excited because ButcherBox's Bacon for Life is back. And it's even better because for a limited time ButcherBox is giving you $20 off each box for the first five months of your membership. That's free bacon for life, and up to $100 off. Just go to butcherbox.com/ifpodcast. That's butcherbox.com/ifpodcast to get one pack of bacon for free in every box for the rest of your life as well as $20 off each box for the first five months of your membership butcherbox.com/ifpodcast. We'll put all this information in the show notes. 

One more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense, because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting. It's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup maybe playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That's because ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years. 

Conventional lipstick, for example, often test high in lead and the half-life of lead is up to 30 years. That means, when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so, you can truly feel good about what you put on. And, friends, these products really, really work. They are incredible. They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life. And their makeup is amazing. Check on my Instagram to see what it looks like. 

Tina Fey, even wore all Beautycounter makeup when she hosted the Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well.

And lastly, if you're thinking of making Clean Beauty and Safe Skincare, a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show

Melanie Avalon: Hi everybody and welcome. this is episode number 280 of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hey there.

Melanie Avalon: I'm just thinking 280, Cynthia, is there something that we should do fun for episode 300?

Cynthia Thurlow: Yes, I think we need to come up with a fun like giveaway or bonus or what do you think?

Melanie Avalon: These are really fun, Gin and I would usually do for milestone episodes, Ask Me Anythings, so then we can just like anything goes. And it's kind of like refreshing because it's not fasting related, just like life related. Those are fun.

Cynthia Thurlow: Happy to, although it's funny. I think I'm starting to get inklings of things that people want us to talk about because sometimes they'll send it to me and my team in the DMs and I'm like, "Please email the podcast. We can't keep track of all this stuff." Yeah, that would be a lot of fun.

Melanie Avalon: Yeah, which is a way we could do that and a giveaway or something. Awesome. I have another question for you. This was appropriate timing. It was yesterday that you were talking to me, and you're on the way to buy pet food. And I had just interviewed Dr. Karen Becker, the author of The Forever Dog. I'm super curious. What do you feed your dogs?

Cynthia Thurlow: We feed what is considered to be grain-free, largely grain-free food. So Acana and Stella & Chewy's, and there's a couple other brands that are seemingly expensive that we give our dogs, but for me, it's the right decision. I have a dog that's 10 and one that's almost nine and they can walk minus the humidity in the summer they normally walk four or five miles a day. So, they're doing really, really well. Other than having yearly checkups at the vet, they rarely ever get sick. So that's worked really well for them that drives my husband crazy because with two dogs, two doodles that have to be groomed every month and have crazy expensive dog food, it ends up being a labor of love. Like I always say, "We love our dogs and this is what I feel is the best choice for them." If you look at them, they're super healthy and alert and smart and active, and they say they're a reflection of how we perceive their lives should be, and so they're joy in our lives. But how was your interview?

Melanie Avalon: It was absolutely amazing. I cannot recommend her book enough. Again, it's called The Forever Dog. She talks about everybody. When people I've had on my show, Jason Fung, Tim Spector, David Sinclair, Dom D'Agostino, literally, even if you don't have a dog, you will learn so much about human health and longevity, and health span and lifespan. It's just shocking, we think it's bad with processed foods for the human food. The pet food industry is, it's really shocking, like, what we're feeding our pets and how it's affecting their health.

Cynthia Thurlow: It's garbage.

Melanie Avalon: It's very eye opening. What's really interesting too, is she was saying that, for the book, she interviewed all these people, she would often ask them what they would feed their pets. And often it would be like this awkward silence. Where they would have a moment and think, "Oh, I'm feeding them," probably what it shouldn't be.

Cynthia Thurlow: Well, it's unfortunate because I got my first dog right out of college. And the vet at that time recommended a brand called Eukanuba, which I thought was the best dog food in the world, because I didn't know any better. And I had a Bichon Frisé, so I had a very small non-shedding dog, and she was just the sweetest, sweetest dog. And I came to find out the most conventionally made animal feed or animal food is really a byproduct of grains, and fillers, and a lot of foods that tend to be allergenic for pets. So, it was really very interesting. And obviously, I haven't had the opportunity to read her book or interview her. But I would imagine that the way that we feed our animals is in a large part comes from a place of ignorance. Like, I know, there's a really wonderful Facebook group that I'm a part of, where basically, pet owners can ask questions, and the vets in the group are wonderfully gracious with their time. Whenever nutrition comes up, they are very anti raw food. And I do occasionally do raw food for the dogs, but not often. They're anti raw food, they're anti grain, they're pro-grain anti, no grains, and keep citing literature about hypertrophic cardiomyopathy for dogs. And it's been very interesting, because I would imagine most veterinary specialists are like most medical trained professionals, and that we get little to no nutrition, like, truly get nutritional training, unless it's someone that's in the researching industry. And I would imagine, it's probably no different for vets, I would imagine by based on what I know.

Melanie Avalon: It definitely is. Actually that was a big part of what she talked about, and there's so many things that were just mind blowing. For example, I've been fascinated by this for a long time, and it's the fact that we have this idea often that it's not safe to feed our pets "human food" that will injure them or that they'll only be healthy if they eat pet food. And it's this fear based on, just not based on reality, but created by the pet food industry. Do dogs not eat real food?

Cynthia Thurlow: Well, it's funny. I have a labradoodle, and labs are known for being just prodigious food hounds. And he will eat just about anything. He'll eat sugar snap pea, he'll eat a cucumber, he'll eat a piece of meat, he would eat anything. My golden doodle is very discerning, will only eat protein. But it's really interesting to me, like when I buy them, when I would effectively call a treat, but it's literally dehydrated sweet potato or it's a fish skin that's been sourced from a healthy location. That's the kind of treats they get. It's not flour made biscuits. And things when people think of what like what a normal treat is like, but there's so much garbage, even going to the grocery store. If you buy your treats in the grocery store, how many of them have canola seed oils in them and flour. Our dogs, they're canines, they're carnivorous, they're really not meant to be ingesting flour or grains, in my estimation, based on my research, and so my very spoiled dogs get very expensive. Again, using the word treat, it's like a dehydrated sweet potato stick and it's literally just sweet potato and salt. It's mind blowing. And then isn't any wonder that these dogs are dealing with a large part of the animal population. They're overfed, they're under exercised, they're given these rancid seed oils, they're given inflammatory flour that should not be a part of their diet, and they're really meant to just eat meat. 

My vet that I had back in Northern Virginia was great. He used to say, "Listen, I have no problems if you give him sweet potato, if you give him a little bit of green beans, stay away from the fruit. Cooper likes blueberries every once in a while, I give him some blueberries, but he'll eat anything. So, we have to be careful. Like he'll counter serve, he's really [unintelligible [00:15:17]. He ate a block of cheese one night when we had a party.

Melanie Avalon: Well, speaking to everything that you just spoke about. The evolutionary diet of a dog is 50% fat, 50% protein. And now the amount of carbs at like you said, so much of conventional food now is actually very carb rich, because it's cheap. And it's a good filler, and it makes a good texture. And it's just doing an awful number on their health. And then in addition to that, there's often mycotoxins in pet food, it's high in AGEs, she has a whole chapter or section about that. It's just really, really a problem. And what's also really sad, I didn't know this, did you know that vets have the highest suicide rate of any profession?

Cynthia Thurlow: I've heard that, and I don't know if it's because there's not enough people going into the profession. And it's one of the few professions where they can actually euthanize animals as opposed to, traditional kind of allopathic medicine. We do everything we can to prolong life, and veterinary medicine, in conjunction with owners, they can help hasten an animal's demise. I don't know if it's because of-- there's probably a variety of factors is what I'm trying to say. But I was surprised/not surprised to learn that

Melanie Avalon: I think that's a huge part of it because not only is it the frustrations of the conventional medical system in general with being-- in general, not preventative, so being reactive, and then coming from a model where it can be hard to address the health of these pets for them, what you said, it's the only profession where you actually euthanize, so, yeah.

Cynthia Thurlow: I couldn't deal with that. I affectionately refer to the time we will not speak of with the vet, because Cooper's 10, and we just had his yearly vet visit, and he's doing well, and I told her, I said, "We refer to it in our house is the time we will not speak of," because there will be a time that we will have to have some tough conversations. And the one thing about pets that if you have a pet, then you understand this, we're on borrowed time from day one. We know that we're going to outlive our pets. And we have these perfect little beings for a period of time. Dogs and cats and other types of animals really teach us to be present and to be grateful, because each day is a gift, we don't know how many days we're going to have with our pets. So, you have to make it count.

Melanie Avalon: Exactly. So, I will put a link in the show notes to the interview won't be out yet, but to her book. And I just want to emphasize, it's so approachable, again, so nuanced, and sciencey and deep, but it's very comprehensive, and how to navigate the pet food system and to find what works for you in your budget. If you want to go all out and make your own, if you want to still buy conventional food, like she makes it very accessible. So, I'll put a link to that in the show notes. Is there anything else new with you in your world before we jump into questions?

Cynthia Thurlow: No, just gearing up to launch some programs in September, that's our big focus for the month of August. So, IF:45, which is the 45-day intermittent fasting program and then Wholistic Blueprint, which is the 12-week program that allows women to do DUTCH testing and GI-MAP and other types of hormone testing. So, in my world, that's a large focus of the month of August, so for listeners, if they're interested in getting on the waitlist, we will put links in the show notes so that you can learn more about each program.

Melanie Avalon: Awesome. 

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Shall we start off with a listener question?

Cynthia Thurlow: Absolutely. So, this is from Nikki. Nikki says, "Cynthia and Melanie, I know you've touched on this from time to time, but I don't remember a lot of discussion on it on any of your podcast. If I'm wrong, please let me know. I'm pretty sure based on how my last period went that I have fibroids, really heavy period, soaking a pad once an hour and passing clots the size of golf balls. Prior to this, my period has always been light to moderate. Also, my stomach always looks bloated even when the rest of my body looks pretty fit and toned. Though I understand that could also be many other things like insulin resistance, cortisol, etc. I will get it properly diagnosed. But I'd like to go into that appointment with a good understanding of possible noninvasive treatments because everyone I know, my mother included, who had this ended up getting a hysterectomy, which I think sounds terrifying. I know Gin mentioned using Serrapeptase to clear hers, and yes, Melanie, I have your supplement and just started taking it. But what else? Should I take more than one Serrapeptase per day, does fasting help? What about nutrition or other supplements? Thanks all for your help. Nikki. P.S. Cynthia, I'm 40 years old."

Melanie Avalon: Awesome, Nikki. Well, thank you for your question. So. I'll just speak briefly to the Serrapeptase part of it. And then I was really excited because I wanted to have this question on, but fibroids is not my forte. But Cynthia said she knew a lot about the topic. So, it was perfect. But for the Serrapeptase. That is one of the reasons that people will often take that supplement. So, what it is, is it's a proteolytic enzyme created by the Japanese silkworm. When you take it in a fasted state, it actually goes into your bloodstream and breaks down problematic proteins in your body. And so, it can really help fibroids and that is the reason that Gin started taking it, and she did effectively clear it with hers. Just to answer your question about taking more than one per day, I think that's fine. I would dose up and see how you react. I personally take two per day. So, you could try starting with that. But see how you react, you could even take more. If anybody is interested, you can get it at avalonx.us. And the coupon code MELANIEAVALON will get you 10% off, but I will let Cynthia speak to the rest of it.

Cynthia Thurlow: That's super interesting about Serrapeptase. So, because you're 40, Nikki, you're very likely in perimenopause. What you're really speaking to is relative estrogen dominance. This is when your ovaries are producing less and less progesterone, you may not be ovulating every month. In response to that you have a relative estrogen dominance and more circling estrogen than progesterone. This is super common. This actually happened to me. I did not have fibroids, but estrogen dominance is what will feed those symptoms, you're experiencing, very heavy, very clotting periods. And conventional allopathic medicine will offer you options like synthetic oral contraceptives, they will offer you things like an IUD Intrauterine device. And ablation which goes in and actually destroys the lining of the uterus, or a partial hysterectomy, which is what you mentioned your mom had gone through. I don't think any of those are necessary per se. There are definitely a lot of things that you can do proactively before you ever need to get to that point. But, again, I would definitely have a conversation with your GYN or your primary care provider.

Estrogen dominance is a constellation of different symptoms. Again, largely I suspect yours is related to life stage, but it can also be related to poor liver detoxification, your gut health, if you're not getting enough fiber in your diet, if you're consuming too many processed sugars, I'm sure if you're a listener to this podcast, you probably aren't. But I just mentioned that along with stress. You can even if you err on the side of being someone that has polycystic ovarian syndrome, I just did a really great podcast with Dr. Felice Gersh on that, you can definitely check that out. You can actually get aromatization, which means you can aromatize testosterone to estrogen, which can contribute to more circulating estrogen. Even things like poor gallbladder function can also impact that. And the other thing to think about is that we were exposed to estrogen mimicking chemicals throughout our lifetime. And I find for many women, whether it's through a personal care products or environment or food, our perimenopausal years are really when we start to see this tipping over of a bucket. So, throughout our lifetime, we get exposure to these chemicals and then in perimenopause, everything kind of goes haywire.

So, things to think about are an anti-inflammatory diet. So really thinking about, are you eating gluten? Are you eating dairy? Are you drinking too much alcohol? [unintelligible 00:25:54] any processed sugars? There are specific herbs that we know that can be beneficial for estrogen dominance, things like turmeric and ginger, which I love, as well as supplements like Chasteberry and Milk Thistle. Milk Thistle, in particular is very helpful for liver detoxification. Really digging into gut health. So, doing a GI-MAP, which is a DNA based stool test, looking at a DUTCH, which is a dried urine and saliva-based test, making sure your blood sugar is properly managed. I find for a lot of people, the lifestyle changes first and then really leaning into nutrition. And then lastly, supplements, and then if it's not helpful or effective, seeking other options through your primary care or GYN's office, but you absolutely can navigate perimenopause.

Unless you've been told you have a fibroid, obviously your GYN could do an internal examination and then if necessary, can do an ultrasound to look for that. But I find most estrogen dominance symptoms are improved upon by lifestyle changes first, and not every woman in perimenopause needs to go on synthetic hormones, get an IUD, have an ablation or hysterectomy, if they're willing to put in the work. Obviously, fasting and eating less often can be certainly very, very helpful. I would be interested to see how you respond to serrapeptase. As Melanie mentioned, that may be very, very helpful for you. Keep us posted.

Melanie Avalon: Thank you, that was so overwhelmingly comprehensive and helpful. All right, so we have a question or some feedback on a question from Lucy, and the subject is, "My Story and Getting Started Again." And Lucy says, "I am a 28-year-old female from Wales, UK. I started listening to your podcast about a year ago. When listening, I fell in love with IF and starting my journey. I started researching IF, and I came across your podcast when I wanted to lose weight in January 2021. I've never been a large person, a UK size eight. But after having many infections, my metabolism basically shut down and I put on quite a bit of weight during the winter of 2020. The pandemic didn't help ha-ha. 

After starting IF, I felt amazing. I started running, my skin cleared up and I stopped having infections and I lost two stone in weight which is about 28 pounds. I felt I was getting intuitive with my eating and was fasting 20 hours of the day and had a four-hour eating window. Then July 2020, I suddenly started getting hungry all the time. Waking up and wanted breakfast, I never ate breakfast, even before fasting. So, this was strange. I remember when you said on the podcast about knowing how when your body is needing food and when it's just cravings. This wasn't cravings and I decided to listen to my body and I had an eight-hour window for a few days. I told myself that come Monday I'll try and get back to my normal fast. On that Saturday, I found out I was pregnant. So, I definitely think my body was giving me signs to eat for the baby. I didn't do IF during pregnancy of course, and now my baby girl is five months old. 

I'm finding it hard to get back into IF. I want to do it for my health. However, as I'm off work on maternity leave, I find I'm always reaching for snacks, also as I am taking the baby playgroups, etc. The other mothers and I often go to a cafe. I don't want to be that person who doesn't go because I'm fasting as this is the only social life I have at the moment. I can't really go and sit with just water. I don't like tea or coffee. The only thing I can think of is on these days I adjust my window to open and close at an earlier time. Any advice on this and how I can just get started again? Thank you. And again, sorry for the long email. I love the podcast. Best wishes, Lucy."

Cynthia Thurlow: Well, Lucy congratulations on your baby. It isn't clear if you're breastfeeding. If you are breastfeeding, I do not recommend fasting, you are feeding your own baby and you don't want to restrict your food intake. If you are not breastfeeding and you're feeling like you're really struggling to recommit to fasting, maybe you need to just have a more relaxed feeding window. It could be that you have a 10-hour feeding window, maybe a nine-hour feeding window, I would encourage you to experiment a bit with either different types of herbal teas, like green tea, or black tea, or even adding things like high quality salt or cinnamon to your coffee to make it more palatable. There are compounds in bitter coffee and bitter tea that are beneficial in a fasted state. I myself learned to drink green tea, I'm not a coffee drinker by drinking it iced, so I would brew it, I would ice it, and then I would stick a straw on it and drink it. That was how I started doing it, because there's just so many benefits. But, again, it's not entirely clear if you are breastfeeding. And if you are breastfeeding, I would definitely recommend you hold off until you're no longer breastfeeding to get back to fasting. Melanie, do you have any suggestions?

Melanie Avalon: So, first of all, echoing what you said about, congrats on the baby. And also, the concerns about the breastfeeding or not. So, I'll just answer it based on assuming that it is a time that you'll be getting back to fasting and are not breastfeeding. I like what you said about the tea and the coffee and trying different varieties, that didn't occur to me, that's actually a good idea. I would challenge your idea, Lucy, that when it comes to the playdates and stuff. I think you have two options here. One, you say I can't really go and sit with just water, you actually can go and just sit with just water. And I say that just because we get a lot of fear surrounding social acceptance and what people will think and will it be weird, and if people are eating or drinking coffee, and I'm not like what will they think. But especially it sounds like this is something that you go to regularly. You really can go and drink water, and it might feel weird at first, but especially if this is something that you're doing a lot, people will adapt. And it's really a matter of how you feel about the situation. And you know what makes you feel good in your body, rather than what other people think. And that's just my personal opinion. I also think it opens up a lot of freedom to life when we don't have that concern and that anxiety surrounding us with like the fasting or the eating window. And maybe this is in part just me having done intermittent fasting for so long, and being so overwhelmingly concerned about in the beginning and having a lot of anxiety about it. And now I'm just like, "I don't care." Maybe you get to a point where you're over it, and you're like, "I'm just going to do what makes me feel good." 

For example, I went to a party last night and there was a dinner. I didn't eat the dinner, because it was definitely not food that would have made me feel well. Nobody thought anything of it. Like it's fine. I think people are a lot more concerned with what other people are thinking about them than they're thinking about you, for better or worse. So, that's my one thing. And then the second thing was you saying, could I adjust my window to open and close at an earlier time? And, yeah, you could do that too. That's totally an option. I think there's a lot of options here. And then as far as getting back into the fasting, again, you find yourself always reaching for the snacks. A few different things, I would look at the environmental cues surrounding that, because I know you are off works, you're at home, it's easier for you to reach those snacks. What sort of barriers can you put in place to change that habit? What sort of things are you reaching for? And if there's snacks, and this would be an easy thing to address if this is the case, and I don't know if this is the case. This might be hard to address if these are snacks that you have in the house for other people. But if these are snacks that literally you would just have for snacks, and they're not actually a part of anybody's meal in the house, just don't have them in the house. Make your environment as suitable as possible to you to encourage the habits that you want to have. You can start putting in some systems that you follow. So, you know maybe when you're eating in the house, you only eat at mealtime in the kitchen. And I know it sounds interesting because it sounds so simple to say, "Just don't do it." Like how can that be the answer? But it's sort of the answer because you can really exist in one or two places. You can exist in a mindset of the bright line eating concept. Or, you can exist in a world of where you have a system and you have boundaries and you have lines and it's just yes or no, on or off. So, you do eat snacks or you don't eat snacks, or you can exist in a world where you're fighting that and you maybe eat snacks and you try not to eat snacks and that mindset shift, I think can be huge.

So, if you can tell yourself, "I don't need snacks," then you can stop yourself from even engaging in it, because you're not going to have that debate each time of whether or not you're going to do it. I always referenced this book, again, I wish I had a different title because it makes it sound like it's only about binge eating, which it's not. But I really like Glenn Livingston's book Never Binge Again, it's really about engaging with the voice in our head that wants to encourage us to have any sort of eating behavior that we don't want to be engaging in and a reframe for how to address that. I really like that book. I've had him on my show, so I can put a link to that in show notes as well. It's funny because Cynthia's answer, I think, this is great, because we are giving a lot different perspectives, because Cynthia's answer, which I also agree with is maybe you just need to be more flexible with the window. I think that's great. On the flip side, if you do want to try to stick to a stricter eating window, I do think there are steps you can take to try to do that. And it's really just a matter of finding, which approach for you right now is what you want to be doing. Do you have thoughts about that?

Cynthia Thurlow: No, I think Glenn's book is such an incredible resource. I too, have been fortunate to connect with him. I think so much of our conversations in our heads. I reflect back on when my kids were little and certainly in the days of being on a maternity leave, and your days are a little more isolating because your kids are so dependent on you. And they're napping, and they're in diapers. And, your mommy interaction might be the only interaction you have with an adult during the day if your spouse is working outside the home. And so it can be very isolating. I think now at a different stage of life, like my kids are older, and I just don't have the bandwidth to even think about those things. But I remember thinking a great deal very thoughtfully about a lot of different health related issues at that time. So, give yourself grace. Melanie certainly provided a lot of really good resources for books and interviews that we've done with people that are leaders in this space. I would definitely lean into that. I think you're asking a lot of great and very thoughtful questions.

Melanie Avalon: I'm glad you brought that up because I was thinking this. It's something that I haven't had that experience of being a mom and going through this and being on the flip side. So, I'm really speaking from a place of no experience. I imagine it's probably a lot more harder than I imagined. I'm glad, Cynthia, you can bring that perspective to it as well. But either way, you got this, Lucy. 

Cynthia Thurlow: Absolutely.

Melanie Avalon: All right. Shall we go to our next question?

Cynthia Thurlow: Next question is from Nikki. Subject is "Protein and autophagy." "Hi, Melanie and Cynthia, welcome to the podcast. Cynthia, I'm excited about this new dynamic. So, I'm wondering how much protein the process of autophagy generates. Melanie, we have talked about this before in your Facebook group, but that was a while back. I'm hoping maybe there's been more research on the subject. I'd love to get Cynthia's thoughts as well, especially as you're both big proponents of getting enough protein as I am. The two of you, along with other experts like Robb Wolf, Dr. Gabrielle Lyon, Vanessa Spina, Dr. Ted Naiman, all land somewhere in the vicinity of recommending roughly one gram of protein per pound of ideal body weight. Here's my question, how much should the ramp up of autophagy due to intermittent fasting affect your protein goals? In other words, how many grams of protein does autophagy generate? I use quotation marks because I don't know if I'm even thinking about it the right way. If we fast for 18 to 20 hours, for example, we have a lot of autophagy happening, shouldn't that mean we don't need to eat quite as much protein. But if that's true, how much? Is this even possible to answer? Your thoughts would be greatly appreciated.

Melanie Avalon: All right. This may be my most favorite question I've ever received for this show. I love this question. I have thought about this a lot. And unfortunately, I have no idea and the amount of time-- I spent so much time trying to find an answer and I could find nothing. I'm going to keep looking. I also reached out to people I thought might know the answer. Authorities, authors I've had on this Biohacking Podcast, and nobody knew the answer. I just wanted to include it to say that it's something I've thought about I don't know. I do wonder, though, if part of this, and this is just me hypothesizing and not knowing really what's happening, but there's been quite a few studies on fasting and muscle mass, very favorable for the effects on muscle retention. I mean, I don't know but I do wonder if, this is involved a little bit. But it's a really good question. And if anybody sees or hears at any point, the answer this question, please let me know. And if I ever have the honor of interviewing Peter Attia, I'm going to ask him this because I would love to hear his thoughts on it. Even though he seems to be-- I don't know, not as much in the fasting. His views on fasting are very interesting these days. Do you have any thoughts at all?

Cynthia Thurlow: I mean, nothing that is conclusive. I think the longer I fast and the more research that I look at, the more I'm a proponent of just remaining open minded the possibility that sometimes we don't have the answers. I am definitely very aligned with Ted Naiman in that. I'm not a huge fan of long fasts, especially for people who are at goal weight or healthy weights. And so, it's impossible to measure autophagy at this time, unfortunately. And I think there just needs to be more research, whether or not that's going to be information that we have accessible to us in the near or the long term. I'm not sure, but it's certainly a great question. Thanks, Nikki.

Melanie Avalon: I'm actually really surprised. I'm sure somebody studied this. I couldn't find it. And I don't know if it's that I can't, because for people who go down the rabbit hole of PubMed and stuff, sometimes when you're looking for an answer, it takes a while to figure out the keywords that you should be googling to find it. And then once you find the keywords, it like opens up this whole world that answers your question, because you have to figure out how people are talking about it in the clinical literature. And I was like, "Maybe if I can just find the right keywords, I'll be able to find the studies," but I found nothing. I'm going to keep looking. But it's a really interesting thing to ponder.

Cynthia Thurlow: Absolutely.

Melanie Avalon: All right. So, we have a question from Dana. The subject is "More Protein." And Dana says, "Hi, ladies, I asked this question on Facebook. And Cynthia asked me to send it here for many more people to see the answer. Cynthia, can you please direct me to where to find macros for my lifestyle? I have Hashimoto's and remission 10 years, age 64, five to 10 more pounds to lose, gluten and dairy free. IF approximately a five-hour window for two years and active lifestyle. I tend to feel better on low versus high fat. I did strict clean keto, less than 20 grams of carbs for one year, a few years back, and it really messed up my thyroid. My body seems to love carbs. Thank you. Thanks for all the things you do."

Cynthia Thurlow: Dana, thank you for your question. I would say first and foremost, there's no way to provide a macro breakdown for every single listener because there's so many different variables, you're obviously in menopause. I love that you're already doing gluten and dairy free. That's certainly very helpful, especially keeping Hashimoto's which for anyone who's listening who's not familiar with that, that is autoimmune hypothyroidism, so underactive thyroid. The first things that kind of really stand out to me is, are you varying your fasting window? I talk a great deal about this in my book, Intermittent Fasting Transformation, I love that you're active, and that you've determined that you do better on low versus high fat foods. I generally don't recommend anyone do sustained ketosis. Meaning, someone doing strict keto for a long period of time. I do think that we need a carb cycle for that low. Meaning, you want to kick yourself out of ketosis. And this is something that I try to document as much as I can on IG stories. Examples of meals that I'll put together on days when I'm lifting heavy, when I will increase my carbohydrate intake, and getting carbs from low glycemic berries, maybe I'm having squash or sweet potato, etc.

I would encourage you to vary what you're doing. I don't think anyone should do the same fasting window every single day, 24/7. I do encourage you to adjust your carbohydrate intake based on your physical activity. And I would definitely encourage you to vary what you're doing. I think that it's certainly super important to be doing strength training, to make sure you're getting high quality sleep. High quality sleep is if you're not measuring it on an Oura or a WHOOP band, waking up rested, having plenty of energy, managing your stress, all of which are very, very important. And really focusing in on a nutrient dense whole foods diet. So, protein centric diet 100 grams a day is what you want to aim for. So, more protein in that five-hour window because you could be that you're chronically under eating, if you're just having one meal in that five-hour feeding window. I hope that helps. How about you, Melanie?

Melanie Avalon: Yeah, I agree with everything that you said. Something I'm really curious for me personally, is at least right now because I haven't hit perimenopause, I haven't hit menopause. And I have done strict keto diet. For me, personally, I felt a lot better, especially with intermittent fasting. Doing a high carb lower fat diet with intermittent fasting. What I'm really curious about is when you're at an older age, like perimenopause or menopause, this approach of having more carbs, can that be a metabolic fix for most people or am I going to hit menopause, for example, then not be able to do my high carb low fat anymore. But I do find that I think a lot of people get in these restrictive mindsets where they're doing a lot of fasting and they're doing a lot of ketos. And like Dana says they might experience thyroid problems or just not or even not the weight loss that they want. And they actually find a benefit when they do bring back the carbs. I think it's great that Dana is intuitive with her body and realizes that her body loves carbs. I do think it's important to-- when it's carbs, there's different types of carbs. So definitely finding the right type of carbs that work for you. I know she's literally asking us how to find the right macros that would work. But I would also encourage her to if she is working in the carb paradigm, she might do better with starches, for example, or she might do better with more like fruit-based carbs. 

For me, I do so well with fruit, starches, not so much. If I do starches, my blood sugars are high, I don't feel good, and it's really, really interesting. So, it's something where-- she wants us to direct how to find the right macros, but it's something she just literally has to test for herself. We can't know what's going to work better for her. I do think it's important for a lot of people to lose the carb fear, because I think a lot of people have carb fear.

Cynthia Thurlow: I think it's unfortunate because I cannot tell you how many people are paranoid. I remind people that there's different types of carbohydrates, like a processed carb, like bread or pasta is very different than having a root vegetable or a tart apple or, a small orange, very, very different. And depending on whether or not your insulin sensitive, and really the only way to know that is you need some lab work done, you can get a glucometer or continuous glucose monitor. Knowledge is power. And I find more often than not women are insulin resistant, perhaps even unknowingly if they're not particularly overweight. And they have no idea what the net impact of certain food choices are. And it could be as unique as each one of us. I talk very openly about the fact I can eat tropical fruits without any trouble. But if I eat a plantain, my blood sugar spikes, and it doesn't matter how I eat it, I've tried many different variations. I just don't eat plantains now. But I think that this requires more information, like really having a conversation with your internist, your primary care provider getting some baseline labs, I always say get that fasting insulin, get the fasting glucose, get inflammatory markers.

The other thing that I didn't mention, Dana, is that, depending on whether or not you're taking hormone replacement therapy that can impact your insulin sensitivity as well. We know estrogen is an insulin sensitizing hormone along with a little bit of progesterone, can be very helpful not only for your thyroid, but also for insulin sensitivity. So, a lot to unpack here, but hopefully we've given you some things to think about and consider, but carb fear is a huge problem. I agree with you, Melanie.

Melanie Avalon: Hi friends, I'm about to tell you how to get 10% off my new magnesium supplement. Yes, exciting news. My Magnesium 8 Broad Spectrum blend is here. Magnesium is such a crucial mineral in the body. It's involved in over 600 enzymatic processes. Basically, everything that you do requires magnesium, including creating energy from your food, turning it into ATP and the mitochondria, boosting your antioxidant system. Magnesium has been shown to help with the creation of glutathione, regulating your blood sugar levels, affecting nerve health, muscle recovery, muscle contractions, supporting cardiovascular health and blood pressure, aiding sleep and relaxation and so much more. It's estimated that up to two-thirds of Americans do not get the daily recommended levels of magnesium, and on top of that, magnesium deficiencies can often be silent because only 1% of magnesium is actually in our bloodstream. So, that might not be reflective of a true magnesium deficiency. 

Our modern soils are depleted of magnesium, we're not getting it in our diet. That's why it can be so crucial to supplement with magnesium daily. I wanted to make the best magnesium on the market, and that is what Magnesium 8 is, it contains eight forms of magnesium, and they're most absorbable forms, so you can truly boost your magnesium levels. It comes with the cofactor methylated B6 to help with absorption, as well as chelated manganese because magnesium can actually displace manganese in the body. My AvalonX supplements are free of all problematic fillers, including rice, which is very, very common in a lot of supplements, including some popular magnesium supplements on the market. It's tested multiple times for purity and potency and to be free of all common allergens as well as free of heavy metals and mold, and it comes in a glass bottle to help prevent leaching of toxins into our bodies and the environment. 

Friends, I wanted to make the best magnesium on the market and that is what this magnesium is. You can get Magnesium 8 at avalonx.us and use the coupon code MELANIEAVALON to get 10% off your order. That code will also work on all my supplements. Including my first supplement that I made, Serrapeptase. You guys love Serrapeptase, a proteolytic enzyme created by the Japanese silkworm that breaks down problematic proteins in your body and can help allergies, inflammation, wound healing, clear up your skin, clear brain fog, even reduce cholesterol and amyloid plaque. All of this is at avalonx.us, that coupon code MELANIEAVALON will also get you 10% off sitewide from my amazing partner MD Logic Health. For that, just go to melanieavalon.com/mdlogic. You can also get on my email list for all of the updates, that's at avalonx.us/emaillist. I'll put all this information in the show notes. All right, now back to the show.

Cynthia Thurlow: Next, we have a question from Angela. Subject is "IF and gargling saltwater and/or mouthwash." "Hello, ladies. I've been intermittent fasting since February of 2019, and will get a bad taste or smelly breath. I tried to drink water throughout the day and the peppermint drops you've mentioned in the podcast definitely help. But if it's related to bacteria, I'd like to gargle with salt water or mouthwash and I'm concerned it will break my fast. On a side note, I go for regular teeth cleanings every three to four months to help with wine and coffee stains. And I haven't had a cavity in quite a while. I love the IF lifestyle and it suits me well. I normally have a four-hour window, but I'm more relaxed on the weekend. But we usually maintain 14 to 16 hours of clean fasting on weekends. Thanks for everything. I really enjoy all of the podcasts and listen to them over again."

Melanie Avalon: Awesome. Well, thank you, Angela, for your question. This is perfect timing. I actually interviewed last week, the cofounder of a company called Bristle. Did I tell you about Bristle, Cynthia?

Cynthia Thurlow: No, hmm-hm.

Melanie Avalon: Oh, my goodness, my new obsession. So, they're so cool. It was so amazing to connect with a co-founder, I was blown away by the science that's going into this. They provide an oral microbiome test. And it's like a spit kit, a saliva test, super easy to do, you send it off. And then you get a profile of the oral microbiome in your mouth. And they give you the raw data of all the strains in your mouth, but then they also group it by how you compare to healthy people, bacteria wise when it comes to issues like halitosis, which is bad breath like Angela speaking of, also cavities, gum inflammation, and also gut inflammation. Then they make personalized recommendations for how to address it, and then you can retest. And so, like the recommendations, they basically list like specific ingredients, or even oral probiotics that might be beneficial. So, it's super cool. It might be a cool resource for Angela to try to maybe see what's going on. And so, you can go to melanieavalon.com/bristle, that's B-R-I-S-T-L-E and the coupon code MELANIEAVALON, will get you 15% off sitewide. And this is super amazing. It was just going to be 15% off for the one-time kit, but they said they would give it to me for this subscription, which is super amazing because the subscription is already discounted. So, you can get 15% off on top of that. So, I highly recommend that. 

To go to Angela's specific question. Gargling with salt water or mouthwash, so saltwater, zero concern about that breaking your fast. Mouthwash more iffy, it depends on the ingredients in the mouthwash. That said, you are not swallowing the mouthwash. So, you're not having that effect. But we do know that the flavors can have an effect on insulin and some mouthwashes are sweet. I've been trying so hard to find a mouthwash that's not sweet because I had one that I really, really liked. It was Desert Essence prebiotic plant based brushing rinse. Honestly, I don't know if they're just using that word probiotic because it's a keyword. I was looking at the ingredients. And I was like, "I'm not really sure if this is actually a probiotic," but maybe it is and I probably should have asked this when I interviewed bristles. I think I might send them a follow up email and ask them. I loved it because it was so minty, not sweetened. It never gives me the perception because I'll use it during the day. It doesn't give me the feeling or the perception at all that I'm breaking my fast. 

They've stopped. I don't know if they've stopped making it. It's really hard for me to find now, so I'm like on the hunt to find another one that I really like. But long story short, my opinion on mouthwash, and I'll be super curious to hear Cynthia's thoughts because we've talked about this topic a lot in the show, but I haven't heard Cynthia's thoughts on it. I wouldn't overwhelmingly stress about it. I would find a mouthwash that doesn't taste sweet and super flavored and I wouldn't stress about it like. When it comes to fasting, I think there are things to be really concerned about putting cream in your coffee. And then, there are things that I think aren't as big of a deal like, are you finding a minty mouthwash? Those are my thoughts on the mouthwash. Do you have thoughts?

Cynthia Thurlow: Well, I interviewed the CEO of Primal Life Organics. Trina Felber, who's a fellow advanced practice nurse, and we will link this in the show notes. She talks a great deal about, we have an oral microbiome, we have our gut microbiome, we have a vaginal microbiome and what effectively what mouthwashes do is they disrupt the oral microbiome, so I don't use any mouthwash products and generally recommend that we avoid them unless it's something very specific that's been designed that is not going to disrupt the oral microbiome.

And as someone who is completely anal retentive about my teeth, this is something that-- even when I go to my dentist who has a clean practice, I don't get fluoride, I don't get mouthwash there. I mean, we have these-- it's a negotiation. But I follow Trina's advice very closely, again, she's another advanced practice nurse. I find that things like saltwater and gargling are actually great. It's not only great for stimulating vagal tone, and your vagus nerve is this longest nerve in our body. It is very important for heart rate variability, it taps us into the parasympathetic, which is the rest and repose side of our autonomic nervous system. I always encourage gargling, humming, things like that. But I would avoid mouthwash unless you know it is not comprised of products that are going to kill off beneficial bacteria in the mouth.

Melanie Avalon: So, I'm really glad you brought that up, because I think it's a really important nuance to discuss. And it's another reason that I really like Bristle because I think before interviewing Bristle, I was very black and white about it. It shouldn't be having any of these compounds that wipe out things for that very reason. And I still lean heavily towards that. That said, reading the research from Bristle, if you do this test, some people have pathogenic strains in their mouth that actually might benefit from a temporary, short-term approach with certain mouth washes that have certain ingredients that might target that bacteria. And it's interesting, because one of those studies that they have, and by the way that the Bristle blog is great. If you have any questions about oral health and the oral microbiome, and all of this, they have blog posts about everything. And they're ridiculously nuanced. And they look at all of the studies, and I feel personally that they're pretty not biased when it comes to their agenda and their goals. So, like, there's a really, really fascinating study where they were looking at the effects of a beneficial probiotic on restoring beneficial bacteria populations in the mouth.

It actually had a more favorable effect if they first "wiped out" the oral native population with the certain ingredients and then have the probiotic compared to just having the probiotic. I think the mouth is like the beginning of a massive frontier that I think should probably be as important as gut health, and we're just not talking about it. In general, I do think people are probably doing more damage than not by having these antiseptic mouthwash is just wiping out everything all the time. So, I think it needs to be a more measured approach and a more informed approach. And that's why I really like Bristle, for example, because then you can see, do I have pathogenic bacteria that I potentially need to be addressing compared to-- because if you don't, then you definitely shouldn't be having those ingredients. If you do, it might be something to think about and what approach are we going to take to address it? I'm just very excited about this topic and what we continue to learn in the future.

Cynthia Thurlow: Yeah. I think, for me, the understanding that there are these different microbiomes in the body, and they all impact one another. So, if you have a lot of dental caries, or have a lot of gingivitis, or a lot of mouth issues that can impact the health of your gut microbiome, your gut microbiome can also be impacted by your vaginal microbiome. I mean, it's all interrelated. And as someone that's at a different life stage, it's something that suddenly I've become very interested in. As an example, my husband, from the time that I met him 20 years ago, always use Listerine mouthwash. And to him, having his mouthfeel tingly was a sign that it was clean. And, boy, was he disappointed to learn he was actually killing off beneficial bacteria in his mouth. And so, I've got him completely weaned from that habit. But he misses to this day, he misses that feeling that tingling in his mouth. And so obviously, if Melanie and I come across products that allow us to not kill off the beneficial bacteria, we'll definitely make sure we pass those along as well.

Melanie Avalon: One last oral health related question for you-- oh, wait, before that, Cynthia, you're talking about the vaginal microbiome and how these things can affect each other. There was a really interesting study sort of recently. I don't know, I say that a lot. It was probably a few months ago. Looking at SIBO, I don't know if you saw this, because we often think that SIBO, small intestinal bacterial overgrowth is from colonic bacteria in the colon, migrating up to the small intestine, which very likely, maybe it was actually positing that, in part might be the oral "bad strains" from the oral microbiome migrating down. So, it's really interesting.

Cynthia Thurlow: Yeah. It's all interrelated, that's what most people aren't talking about. It's not like there's an ecosystem in the gut that doesn't communicate the rest of the body at all.

Melanie Avalon: Yeah. Do you do oil pulling?

Cynthia Thurlow: No. I do tongue scraping. And then I have Primal Life Organics' tooth powder and like a tooth serum. And then I have their-- it's like a tooth whitening product.

Melanie Avalon: They don't have a mouthwash, right?

Cynthia Thurlow: Hmm-hm.

Melanie Avalon: I'm on the hunt, because I have an oral breath fixation. And I'm on the hunt to find-- I really liked that one I was using and the fact that they're not making any more it makes me so sad. I'm paying an arm and a leg to like, because on Amazon they'll have like the last few bottles from third party sellers. The amount of money I'm paying for this mouthwash, because I'm trying to like get all the last bottles.

Cynthia Thurlow: You're like, "I must have them all."

Melanie Avalon: I know. It's bad. All right. I think we have time for one more question. This is from Barbara. The subject is "Over 70 Women and IF." And Barbara says, "I'm very interested in IF. I need to lose 80 pounds, at least. I scrolled through all your success stories. Any stories you've heard of 72 plus year old women who have had joint replacements, who have lost their weight with IF." I love these questions where I haven't heard Cynthia specific answer yet. It's like I'm listening to the podcast. So, yeah.

Cynthia Thurlow: Well, thank you for your question, Barb. I would say first and foremost, there's a lot of things that can impact, significant weight loss. And I would make sure that you have a conversation with your primary care provider internist, because if you're taking any medications right now, for blood pressure, or insulin resistance, or cholesterol, you may need adjustments, but I've had many menopausal women who have had significant weight loss improvement, or that have been struggling weight loss resistance, in conjunction with intermittent fasting and changing their diet. So, to say one without the other is really putting you at a disadvantage. So, eating less often combined with an anti-inflammatory diet, and that could look like not eating bread, not eating pasta, maybe you're getting carbohydrates from other sources. But if you have more than 80 pounds to lose, I would want to combine that with-- I know you mentioned that you had some joint replacements, so I'm not sure if you can do water aerobics, where you're being taught by an instructor who is knowledgeable about women that have had joint replacements, it'll be gentle to your knees, maybe your hips and your shoulders. Finding ways to be as active as possible, along with high quality sleep, and managing your stress because there's no one in the past two years who hasn't had more issues with higher amounts of stress than usual.

When it comes to deciding what fasting window is appropriate for you. If you are coming from a methodology where you are consuming three meals a day and snacks, the kind of way that I walk women through this as you stop snacking as number one, that will force you to restructure your meals. Even if you're just having two meals in your day, it's going to force you to increase your protein. I'm going to encourage you to reduce the amount of carbohydrate in your diet. I'm not saying anti-carb, but getting your carbs from non-starchy vegetables, salad, arugula, broccoli, cauliflower, and then adding unhealthy fats as appropriate, is really a great way to go, and to not eat from dinner to breakfast. That's the next step. But I would absolutely positively encourage you to have a conversation with your internist, your primary care provider, your NP, whomever it is that you see before you engage in intermittent fasting. Just to make sure they may need to monitor you more closely, if you're on blood pressure medications or diabetes medication, so that they can determine if they need to make adjustments and those medications, but definitely keep us posted. Melanie, do you have anything you want to add?

Melanie Avalon: Yeah, just the only thing I would add is, I'm so fascinated by the trajectory of aging. I remember how you talked about this in your book, Intermittent Fasting Transformation which everybody should get. And you talk about how fasting can be for older women maybe safer. When you're in your menstrual cycle years and your fertility years that it can be more of an issue with over fasting but when you're older, that's a little bit less of an issue. Am I saying that correctly? 

Cynthia Thurlow: Absolutely. 

Melanie Avalon: What I am so fascinated by is the dichotomy of that coupled with, on the flip side, the increased need for protein when you are older. Even people in the low protein camp, like vegan people and Valter Longo, even they say, when you're older that there's definitely an increased protein need after, I think, they usually say after age 60, maybe? I'd have to double check that exact age. So, it's this interesting nuance where, yes, fasting can be very helpful and beneficial and even easier and even, potentially "safer." I'm not a medical doctor, but trying to communicate that concept with you also need more protein. I think the nuance of that is really important in that, yes, you can do the fasting to lose weight, but you've got to be getting adequate protein. And so, you've got to do an approach that will ensure that you get adequate protein. Yeah.

Cynthia Thurlow: And I would imagine, I mean, this is probably the norm is just about everyone listening unless they know otherwise is chronically under eating protein. And protein intake, in particular, for those that are middle aged, and even older than 65, we know that our protein needs and increased substantially because we don't break it down as effectively. And so, we have to almost over bolus ourselves. Most of the patients that I've taken care of over the last 20 years that are dealing with weight loss resistance, or obesity or being overweight and just struggling in those areas. They're not eating enough protein. So, protein is satiating, protein helps the muscle protein synthesis, but in the context of a young woman who has 80 pounds to lose and is very interested in intermittent fasting, I would encourage you to take little steps. You don't have to do anything drastic, not even snacking every day, not eating between dinner and breakfast can have a huge net impact on weight loss resistance.

Melanie Avalon: Exactly. I'm very glad that we're so aligned on this concept.

Cynthia Thurlow: Absolutely.

Melanie Avalon: Also, I'm super excited that we got five listener questions in to make up for last week where we had one listener question,

Cynthia Thurlow: But it's all about balance, listeners. We're always striving for balance.

Melanie Avalon: Yes, so that's an average of three questions per episode, which I think is probably our average. Well, this has been absolutely wonderful. So, a few things for listeners before we go. If you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. The show notes will be at ifpodcast.com/episode280. The show notes will have a full transcript and links to everything that we talked about. So definitely check that out. Then you can follow us on Instagram. We are @ifpodcast. I am @melanieavalon, and Cynthia is @cynthia_thurlow_. All right. Well, this has been absolutely wonderful. Anything from you, Cynthia, before we go?

Cynthia Thurlow: No, keep the questions coming. I mean, we appreciate that we're getting so many because it allows us to keep the podcast really nicely organized, but don't feel like there's no topic that's off that we're not willing to face and chat about. So, don't feel at all uncomfortable. There's probably 20 other people that have the same exact questions and maybe don't have the nerve to ask it. So, nothing is off limits.

Melanie Avalon: Exactly. Thank you for saying that. I cannot agree more. All right. Well, this has been so great. And I will talk to you next week.

Cynthia Thurlow: Sounds good.

Melanie Avalon: Bye. 

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice, and no patient doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs and original theme composed by Leland Cox, and recomposed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

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If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Aug 21

Episode 279: Organic Wines, Blood Ketones, Urine pH, Fasting Insulin, Continuous Glucose Monitors, Appetite Hormones, Lean Protein, ADF, And More!

Intermittent Fasting

Welcome to Episode 279 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

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To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

Visit IFpodcast.com/episode279 For FULL Shownotes, And IFPodcast.com/StuffWeLike For All The Stuff We Like!

LMNT: For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase! Learn All About Electrolytes In Episode 237 - Our Interview With Robb Wolf!

DRY FARM WINES: Natural, Organic, Low Alcohol, Low Sugar Wines, Paleo And Keto Friendly! Go To dryfarmwines.com/ifpodcast To Get A Bottle For A Penny!

The Melanie Avalon Biohacking Podcast Episode #5 - Todd White

Episode 26: IF & Low Sugar/Alcohol/Toxin Wines For Health – Special Interview With Todd White Of Dry Farm Wines!

Listener Q&A: Doreen - My first inquiry

The Melanie Avalon Podcast Episode #70 - Kara Collier (Nutrisense)

Ep. 132 – Continuous Glucose Monitors: Why They’re Not Just for Diabetics Anymore with Kara Collier

NUTRISENSE: Get $30 Off A CGM At Nutrisense.Io/Ifpodcast With The Code IFPODCAST

JOOVV: For A Limited Time Go To joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

For A Limited Time Go To butcherbox.com/ifpodcast And Get Free BACON For LIFE Plus $100 Off Over 5 Boxes!

AVALONX MAGNESIUM 8Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist, And Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 279 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time and get ready for The Intermittent Fasting Podcast. 

Hi, friends, I'm about to tell you how you can get my favorite electrolytes for free. Yes, completely free. And the feedback we have received about LMNT electrolytes from our audience is overwhelming. You guys love LMNT and I'm so excited because our new offer allows new and returning customers to get free LMNT. And on top of that their super popular Grapefruit flavor is back. If you've been having issues with intermittent fasting, electrolytes may just be the thing that you need and/or have you heard of something called the keto flu? Here's the thing. The keto flu is not actually a condition. Keto flu just refers to a bundle of symptoms, headaches, fatigue, muscle cramps, and insomnia that people experience in the early stages of keto dieting. Here's what's going on. When you eat a low-carb diet, your insulin levels drop. Low insulin in turn lowers the production of the hormone aldosterone. Now, aldosterone is made in the kidneys and it helps you retain sodium. So, low aldosterone on a keto diet makes you lose sodium at a rapid rate and even if you are consciously consuming electrolytes, you might not be getting enough. In particular, you need electrolytes, especially sodium and potassium in order for nerve impulses to properly fire. Electrolytes can easily be depleted while intermittent fasting.

Robb Wolf, who as you guys know is my hero in the holistic health world worked with the guys at Keto Gains to get the exact formulation for electrolyte supplements to formulate LMNT Recharge, so you can maintain ketosis and feel your best. LMNT Recharge has no sugar, no coloring, no artificial ingredients, no junk. They're used by three Navy SEALs teams, they are the official hydration partner to Team USA weightlifting, they're used by multiple NFL teams, and so much more. We have an incredible offer just for our listeners. You can get a free LMNT sample pack that includes all eight flavors. Citrus, Watermelon, Orange, Raspberry, Mango Chili, Lemon Habanero, Chocolate, and Raw Unflavored. And the Raw Unflavored, by the way is clean fast friendly. You can try them all completely free when you make a purchase at our link, drinklmnt.com/ifpodcast. You can get this offer as a first time and as a returning LMNT customer. I know there are a lot of returning LMNT customers. The feedback I hear from you guys, "loving LMNT" is amazing. LMNT offers no questions asked about refunds on all orders. You won't even have to send it back. And this offer is exclusively available only through VIP LMNT partners. You won't find this offer publicly anywhere else. So, again, the link is drinklmnt.com/ifpodcast. And we'll put all this information in the show notes.

And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting. It's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer, and obesogens which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup maybe playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That's because ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years. 

Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They are counter time for antiaging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life. And their makeup is amazing. Check on my Instagram to see what it looks like. Tina Fey, even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. And you can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well.

And lastly, if you're thinking of making Clean Beauty and Safe Skincare, a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show.

Melanie Avalon: Hi, everybody and welcome. This is Episode number 279 of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hey, there. 

Melanie Avalon: And Cynthia, I have a fun topic that we can talk about briefly if you would like. You already know this, because I asked your advice about it yesterday. For listeners, yesterday, I went to a gender reveal party for one of my friends and it was an evening event. And I knew there was drinks and wine. I actually asked her ahead of time. I was asking Cynthia, I was like, “Is it okay, if I bring my own organic wine to this pregnancy related event, if there's already drinks?” You said that you thought that would be appropriate. So, I did. But I did not bring Dry Farm Wines and I regret that decision. My [laughs] Oura Ring this morning, it's crazy how much it knows when you're drinking wine you shouldn't be drinking and maybe too much of it and not sleeping well. But what's really interesting is, my sleep was great, just my readiness score is awful. I bring it up because I think I need these moments to remember why I only drink Dry Farm Wines and you recently interviewed Todd White.

Cynthia Thurlow: I did. First of all, it was really interesting to prep for that discussion. And then when I got off the phone, I'm sorry, I got off the recording, I was saying to my husband it has been very common for me over the last several years to just send team members, family members subscriptions to Dry Farm Wines and how easy that has been. And I said, “I didn't fully appreciate and realize the differences between conventional winemaking here in the United States versus natural practices.” Certainly, from this point going forward, I really understand and appreciate the chemical and exposure load that you get from conventional wine, which I was really-- 

Let me be very clear. I think I'm a pretty well-educated person about processed food industry and nutrient dense Whole Foods, but I hadn't really considered the net impact of conventional winemaking here in the United States. And so, that was a really enlightening podcast. I can imagine how you felt differently. I think, if I recall from our conversations last few days, you were planning on bringing an organic option or organic options with you. So, even with the organic wines, you still felt poorly. I wonder if it was the alcohol content.

Melanie Avalon: I was telling you this already. But basically, at home, I only drink Dry Farm Wines. And for listeners that are not familiar, they're not a wine producer. They're like an investigator and a distributor. They go all throughout Europe, only Europe, because Todd says that, “None of the US wines meet their standard.” And I think that's in part, because of just how saturated the US environment is in pesticides, even organic like plots of land. The wineries from there, they did a test. I don't know. Did he bring up the test that they did a while ago and they tested all these different wines in California, including organic ones and every single one tested for pesticides, which is just crazy. They find the wines that are low in sugar, so less than I think one gram, and then low alcohol, so 12.5% or less, and then they test them for heavy metals, pesticides, mold. I noticed such a difference drinking them. 

But what I did for this party was, I do have a collection of wines that are not Dry Farm Wines that are organic that I just have from over the years that I'm not going to drink by myself at my apartment, because I really just drink the Dry Farm Wines. So, I bring them to events like this. But now in retrospect, I'm like, “I should have just brought Dry Farm Wines.” Then again, I did have a lot.

Cynthia Thurlow: Well, maybe it was dose dependent. Meaning, perhaps, if you had had one glass of the organic wine, maybe you were fine. Maybe it was two glasses might have been just enough to disrupt your sleep quality.

Melanie Avalon: Yeah, probably.

Cynthia Thurlow: That's my guess. I always say, “Maybe it's dosage dependent.” I say that to patients like, “Maybe it's the quantity and not so much per se that it was not Dry Farm Wines.” But the one thing that I think I was really surprised by when I spoke with Todd was the differences in alcohol content. Conventional wines can be greater than 15% alcohol versus six to 12.5 is-- Most of the Dry Farm Wines really run and they are, as you mentioned, lower sugar. And so, we know that that impacts us on pretty significant profound ways. So, but did you have fun? 

Melanie Avalon: Yes, I had so much fun. It was fabulous. And even that said, I'm still good. This is not my college days or anything. No, I did. I have not been to a gender reveal party before. 

Cynthia Thurlow: Neither have I. But that also says generationally where I am. My oldest will be 17 next week. And so, I'm just at a different-- When I was pregnant, people chose to either find out at 20 weeks what gender child they were having or not. And so, now, people can find out a whole lot earlier and it seems to be something that's very trendy and fun. And I think there's always opportunities to celebrate babies. It's such a fun exciting time.

Melanie Avalon: Yeah, I agree. It's funny. They wanted you to wear blue or pink based on what you thought it would be. I only wear black dresses. I wear a black dress, but then I wore sparkly shoes that were blue and pink.

Cynthia Thurlow: I like that. You're in a neutral zone. 

Melanie Avalon: Yep. [chuckles] So, yeah. But for listeners, to learn more about Dry Farm Wines, which I'm just so obsessed with, our link will get you a bottle for a penny. So, go to dryfarmwines/ifpodcast and that's where you can get that offer. And then, Cynthia when do you air that episode with Todd?

Cynthia Thurlow: Actually, next Saturday. So, it will be August 13th that episode will air.

Melanie Avalon: Okay. Awesome. So, that'll actually be aired by the time this comes out. We'll put a link to that episode. We'll also put a link to the episode that I did with Todd way back in the day. He was one of my first episodes on The Biohacking Podcast. Well, I'll also put an episode we've had him on the show. So, I'll put a link to that as well.

Cynthia Thurlow: Yeah, he's a great guy. It's interesting, because I'm married to a Todd. And my Todd really likes the red selections from Dry Farm Wines. And it's interesting. We recently placed an order and he always feels there's too much white wine in our house. I think because maybe our guests drink the red wine. This last order that we've received, he has been very happy with.

Melanie Avalon: Well, so, that's something because I know that you personally you don't drink at all, right?

Cynthia Thurlow: I don't. It's the only thing that really erodes my sleep. By this, for everyone who's listening, if you're not yet in the perimenopause range, it is the only thing that gives me hot flashes. So, I just don't drink for that reason because hot flashes, especially when you're trying to fall asleep are not fun. But yeah, that was a large decision why I stopped drinking much of anything. I didn't drink much to begin with. I've always been more of a very, very light drinker.

Melanie Avalon: With me having drank the Dry Farm Wines over the trajectory of there, because I probably started, I don't know, when they were founded.

Cynthia Thurlow: Seven years ago, I think, Todd was saying.

Melanie Avalon: Okay. I started drinking them in probably 2014 or 2015. I probably started drinking them right at the beginning, like 2015. They have not improved, but they have improved. You were talking about the red wine. In the beginning, most of the reds all were very, very light. They didn't have many more robust reds, because I think it's harder for them to find those that fit all their criteria. But they have evolved. That's a good word. They've evolved so much in the red wines that they source and some of their wines are just delicious.

Cynthia Thurlow: Awesome. You can drink them with a good conscience.

Melanie Avalon: Oh, yes. And now, I think I need these nights every now and then, like, last night to further appreciate why I only drink Dry Farm Wines normally. So, before we jump into questions, Cynthia, would you like to tell listeners one more time about the giveaway that you are doing?

Cynthia Thurlow: Yeah. So, this is the last week of the giveaway. And all we're asking you to do is, if you've purchased my book, Intermittent Fasting Transformation, please leave a review, screenshot the review, send it to questions@ifpodcast.com, and you will be eligible for an entry. You have to live in the continental United States and it's a grouping of some of my favorite products and designs for health, and a few other wonderful retailers that I work very closely with as a thank you. We'll pick one winner. This is the last week of the giveaway. So, please make sure you get your entries in and we will look forward to randomly selecting a winner.

Melanie Avalon: And I will just say, so, I know a lot of you guys have Cynthia's book, because we get feedback. I see it in the groups. But we haven't had that many entries and I'm just saying that to say you have a good chance of winning. So, if you have the book-- [crosstalk]

Cynthia Thurlow: The odds are in your favor. [laughs] 

Melanie Avalon: Yeah. I always like to emphasize this because I think giveaways where people think, “Oh, there's so many people entering. I have no chance of winning.” But a lot of people will think that and [laughs] you do have a good chance of winning. And it also just really helps support Cynthia's wonderful book and we'd be so appreciative. So, definitely, definitely do that.

Cynthia Thurlow: And I don't think until I wrote a book that I realized how important those reviews are. So, please know that each and every review, I appreciate on a level beyond I can properly articulate. There are so many people that have really benefited from the book. I'm speaking from a place of gratitude and I would love to be able to send these goodies to one select individual. So, definitely get those entries into us.

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Melanie Avalon: Shall we jump into some questions for today? 

Cynthia Thurlow: Absolutely. 

Melanie Avalon: Okay. To start things off, this is a long question, but she has a fun story and then she has a lot of questions that we could just do rapid fire. This comes from Doreen and she wrote this to us back when Gin was on the show. So, she says, “Hi, Melanie, hi, Gin. Let me start off by saying, I absolutely love the podcast. I feel like you ladies have become my friends. You make me smile and laugh. You're smart. You're funny. Initially, I was listening in no specific order, but then I decided to listen every Monday to the new episodes and backtrack when I'm walking. Like many of your listeners, I have many questions that sometimes get answered before I need to submit them. I have several drafts with questions, but I can't prioritize which questions are the most important. Finally, after listening to Episode 159 with Dr. Anna Cabeca, I've been motivated to get some questions answered.” Really quick question for you, Cynthia. You are personal friends with Anna Cabeca, right?

Cynthia Thurlow: I am. She's wonderful.

Melanie Avalon: I think she's actually been on this show twice and on my Biohacking Podcast, maybe twice. Done a lot of interviews with her. I really like her work. Doreen says, “I am 54 years old, a certified personal trainer and yoga certified. I teach mainly hot yoga. It's very tough with a mask. I was heavy as a teenager at 5’2”, 184 pounds. My family celebrates everything with food. I'm Italian. At 16 with mom's help, I joined Weight Watchers and reached my goal in 1981. I'm still an active lifetime member and still track and weigh every few months. Diet and exercise and healthy eating, I've managed to stay within a six-to-eight-pound window with the exception of having my two children and some health issues. 

In 2015, I was diagnosed with cancer. I caught it early Stage 1. I did have some weight gain that crept up and I don't weigh myself now because of the way my clothing had stopped fitting. My first thought during the pandemic was panic. I'm going to gain weight without hot yoga. So, I took to the pavement, I started walking. During walks when my friends got back to work, I would binge listen to podcasts and I didn't gain the weight. Based on listening alone, I began adding IF into my routine and I feel fantastic. It's also helped with health issues, IBS, and GERD, et cetera. Melanie, I tried to get your book and Barnes & Noble had no copies. I was very excited to crack the book on our road trip from Long Island to Vermont. One of our favorite stops is for a place called the Creamery, which is a cute little country store. It's a constant on our trips to Vermont. I promise there's a reason for this story. 

I'm a shopaholic. So, while my husband and friends were getting the ice cream, I was power shopping around the store. I looked up and could not believe my eyes to my surprise staring me in the face was a copy of What When Wine with Melanie's beautiful face on the cover. I screamed. I was so excited. And of course, I bought it. It was divine intervention and favor. In Ludlow Vermont, they're carrying Melanie's books.” Okay, I just have to stop. This blows my mind. [laughs] I can't believe my book was in this random country store in Vermont. That is so random to me. Do you think these stores just order books and resell them, I guess?

Cynthia Thurlow: Well, I suspect maybe the owner or someone who's connected with the owner probably is a fan. 

Melanie Avalon: Wow. That would be so exciting to me, if I was in some random little country store and saw my book. I would not know what to do.

Cynthia Thurlow: You've made it, you know? You've saturated the rural country market.

Melanie Avalon: I know, I know. So, Doreen, thank you for sharing that story. That really made my day. Okay, so, now, she has rapid fire a lot of questions. Here we go. Number one, “With regard to ketones, pH levels in urine and all measures to determine clean fasting and eating. During the podcast with Dr. Cabeca, she discussed how important it is to test your urine for pH levels regarding ketones. I believed you said one could be burning ketones, even though you don't turn the strip's purple. There's also a question about blood sugar. I remember a discussion of different types of testing for blood sugar and blood fasting sugar. What's the difference? It would be very helpful, if you can clarify the importance of measuring pH levels in urine, ketone burning, and blood sugar, and which tests for IF purposes would be best, and where to get these kits and tests, and will they cost a fortune?” Okay, so, ketones, pH testing, blood sugar testing, would you like to talk a little bit about this, Cynthia?

Cynthia Thurlow: if you've been fasting and you're not new to fasting, then I would not anticipate that you would have urinary ketones present. It's much more accurate to actually test blood. But for the purposes of your constellation of questions, I would say that as a woman that it sounds you're in perimenopause/menopause that it'd be most valuable for you to know a fasting insulin and a fasting blood sugar. And a fasting insulin, you can get drawn with regular lab work. A Keto-Mojo is a good meter to use if you want to track your blood ketones. 

And then lastly, a fasting blood sugar with a glucometer or if you want to have a continuous glucose monitor, typically where I stay, I think it's important to know what your blood sugar is when you are in an unfed state. I think it's equally important to know what your blood sugar is in response to stress, nutrition, meals, exercise, etc. There's a lot of different variables to look at. I did a really great podcast. I know that Kara Collier has been on my podcast and also, Melanie's Biohacking Podcast at least once or twice. And that's a really fantastic resource and we will link that in the show notes.

Melanie Avalon: Do you put much weight into measuring the pH levels?

Cynthia Thurlow: No, I don't. I really don't. I think that there are a lot of metrics that we can measure. It doesn't necessarily mean that the information is all that valuable. Because if you're eating a nutrient dense Whole Foods diet, and you're not drinking excessively, and you're not eating a lot of processed carbohydrates, then ideally, and I have encountered a few functional medicine practices that will have their patients do urinary pH strips, but I think it gets expensive. And I've come to find that most of us like you and I, if you were to measure our urinary pH, it's probably more alkaline based on the types of foods that we eat. 

With that being said, when people are trying to budget for different types of home testing or monitoring, I think the most valuable one of all is really looking at fasting blood sugar or looking at a continuous glucose monitor. If someone is new to a lower carb ketogenic lifestyle, and they have not been in ketosis, and they're obese and overweight, then testing at least initially with urinary strips for ketones can be valuable. But if you have been in ketosis and you've been fasting for a long period of time, they're not going to show up in your urine. They are going to show up in your blood. I don't know if you have anything that you'd like to add to that. 

I think the big thing for me as a clinician is, there're a lot of metrics that we can measure. It doesn't mean we should measure everyone. We should decide based on our budget and our interests what is the greatest priority? I'm getting ready to bring the Keto-Mojo individuals on the podcast to talk more about testing ketones, because I get a lot of questions about it. But it really needs to be taken in the context of what are your risk factors, are you insulin sensitive, what are you trying to measure, what are the metrics you really want to look at and going from there?

Melanie Avalon: Are you interviewing Dorian? 

Cynthia Thurlow: I am, but not until February. Because right now, I'm booking into March. Yeah, which is I took time off around the book launch and now, we're back into eager beaver stage where we're booked out like six months.

Melanie Avalon: I was having flashbacks, because I connected with him right when they launched, I think as well and had him on this show. I think we had him on the show. He's British, right? Flashback to his-- He has the best accent. 

Cynthia Thurlow: And then his wife, I guess, is Emma?

Melanie Avalon: Is she British, as well?

Cynthia Thurlow: No, she's American, but they're really cute. They're cute little couple.

Melanie Avalon: Aww. Yeah, I'll just echo everything that you said just to really bring it into people's heads. With the ketone urine strips like Cynthia said, if you've been fasting for a while, if you've been even ketogenic for a while, you might not see that on your urine. I think they're most useful for somebody going from a standard American diet, not fasting to either ketogenic diet or fasting, because it shows when you start, just in general creating those ketones and the excess are spilling into the urine. But then the body becomes more efficient and you don't see that as much necessarily. So, there's real a time window when I would use those. 

And then for the blood sugar testing, yes, we are major, major fans of continuous glucose monitors. Those will really give you, because you'd asked me about the difference between the fasted blood sugar and then just the blood sugar. It's always blood sugar, but it's either fasted or postprandial, which means after a meal. And the only difference is just based on if you ate or not. And so, the levels might be different based on that. And so, continuous glucose monitor is so helpful or can be, because it shows you constantly how your blood sugar is reacting to fasting or eating short of that with just like a finger prick type situation. And this is what Cynthia said, as well. So, I think we're very aligned, 

I think if you had to choose-- once you try a continuous glucose monitor, you will realize just how much potentially your blood sugar can change even minute to minute. And I say that because you might do a finger prick and get a number that if you had tested 15 minutes earlier would be pretty different. It's much more clear picture with a continuous glucose monitor. If you don't like pricking yourself or you don't want to be pricking yourself all the time and you had to pick one time to prick yourself, I would probably go the Marty Kendall route, which is right before eating to see if you actually are in a lower blood sugar state ready for that meal. Because his data driven fasting is all about how people will open their eating window when they actually have high blood sugar. They think they need fuel, but they actually don't. It's very interesting. The link for that is nutrisense.io/ifpodcast and the coupon code, IFPODCAST will actually get you $30 off any subscription to a CGM program. So, definitely check that out. That can be a really helpful resource. 

Her next question, she says, “I'm in between ADF and one meal a day depending on what's happening in my life. Sometimes, I will do four straight days of 18:6, but then eat regularly on the weekend. I thought this protocol was good. Is it there a gray area and discussion about this topic? Do you agree that every day shouldn’t be a short eating window? Please clarify. I find myself contradicting my thoughts and I feel worried about opening my window too early.” I'm actually very curious your thoughts on this, Cynthia, because Gin would talk about this a lot, which was, in particular in regards to ADF, which is something that I personally have never done ADF. But she would often talk about the importance of if you're doing ADF not having a shorter eating window and not under eating on your fasting day. So, I'm really curious your thoughts on that and also on just if somebody was doing one meal a day, every day type situation?

Cynthia Thurlow: Well, I think listeners are probably not surprised to hear that I don't like ADF or OMAD as a sustained strategy for women or men for that matter, because there's just no way you're going to be able to get enough protein in one meal or this alternate day fasting. And there's a lot of what I believe to be emerging, both anecdotal and also research to suggest, unless someone's really stubbornly obese and is really trying to break through plateaus, most of us that are close to our ideal body weight, you start looking at the law of diminishing returns. And so, you just can't build enough muscle protein synthesis. I've spoken to Gabrielle Lyon about this extensively. I've spoken to Ted Naiman. And for listeners, those are both physicians in that space about how to stoke appropriate muscle-protein synthesis. 

I do like people varying their fasting and feeding windows. I think variety is very important, not just in our fasting windows, but also in the foods we choose to eat. I like a lot of variety. Same thing with exercise. However, especially when someone is trying to figure out what works best for them, it requires a degree of experimentation. What gives you plenty of energy, what supports sleep habits, what is allowing you to break through a plateau, do you need to be honest with yourself about the fact that you're not eating a particularly nutrient dense diet, and then you're attempting to do these prolonged fast to work through challenges that you're experiencing? And I'm starting to believe and starting to speak about this more that I am starting to see many women in particular that are doing this over-fasting, overtraining, over-restriction in an effort to lose weight. And we will obviously unpack more of this as the podcast goes on and I'll certainly be talking about it on my own podcast.

But in the context of this question, I don't like ADF and OMAD for a sustained strategy for women. It’s just impossible to get your protein in. And I'm very protein centric and I admit that. But when I look at the research and when I-- I'm a 51 year old woman. I just realized that I had a birthday last week. I have to remind myself, I mean, you're older. It requires a bit of effort to get sufficient amounts of protein into my diet. It is work that I'm happy to do. But I think in the context of answering this question that that's my prevailing thought process. How about you Melanie? 

Melanie Avalon:I keep rereading her question because I'm actually a little bit unclear now what she's actually doing. Because she says, she's in between ADF and one meal a day, but then she says, sometimes, she does four straight days of 18:6.

Cynthia Thurlow: I think she's doing a lot of variety. 

Melanie Avalon: 18:6, for example, would you consider that like a one meal a day, a six-hour eating window? I guess, it depends what they're actually eating during it. 

Cynthia Thurlow: Correct. I think a lot of people are just eating one big meal and maybe they're not hungry at the end of their six-hour feeding window. And that's the concern that I have. The more I talk to other metabolic health experts, the more I start thinking that we have to be less rigid and we need to really lean in like-- I've been experimenting this whole summer with having a wider feeding window. And, especially, because I've been lifting more, I've been more hungry, I've been breaking my fast earlier, I'm finding that I'm getting better results. And each one of us has different goals and different aspirations. But I think a certain degree of experimentation is important to not be so rigid with-- If something has been working, try something and try something new. We have a wider feeding window. And by wider, it's not my feeding window was 12 hours. It might be an eight-hour, a nine-hour or a 10-hour, so that I can have more meals with my family.

Melanie Avalon: Okay, yeah, I love that. I feel we always say that it's individual and you have to find what works for you, which feels like a cop out answer. But it's so, so true, because people are just so different. 

Cynthia Thurlow: Bio individuality rules. 

Melanie Avalon: Yes. Because me, for example, I do a shorter eating window. Yeah, I was thinking about this with you're talking about how you're struggling to get in enough protein and so many people say that to us. We get so many questions about that. And it's just interesting to me, because it's so easy for me. [laughs] I just eat so much protein.

Cynthia Thurlow: But I think my appetite was different at 30 than it is at 51, because I've tried to reflect on that like, “How much more food did I eat when I was younger?” There was definitely a point in my early 40s that I felt my appetite change significantly. A lot of my patients, and clients, and friends, we'll talk about this openly. We're like, “Oh, yeah, we don't eat nearly as much food.” I think that is a biologic drive. If you talk to someone who's 70, they don't have the appetite they had at 20. It's because ideally, we should not be in an anabolic growth phase at that stage of our lives. Whereas, I have teenage boys and they're very much in this anabolic building stage and they're healthy, they're lean, they're muscular. It's a very different phase of life. And so, I think so much of it's dependent on where we are in time and space. It is a concerted effort. 

For me, to hit my protein macros every day and it's not that I don't like to eat. Protein will fill me up and then I'm full and I'm like, “Okay, now, four or five hours later, I ate another protein bolus.” And that's how I navigate. I eat a lot of eggs. Someone asked me the other day, “How do you get that much protein?” I was like, “I eat a lot of eggs.” Because I can eat a good amount of eggs and I don't feel nearly as full as I would if I ate a piece of steak. But I always like to shake things up.

Melanie Avalon: I'm super curious. When you did have a higher appetite, when you were in your 20s and 30s, did you ever do an approach like me where-- Literally, the foundation of my meals is lean protein., I don't really add-- It's hard to describe, but I basically just eat tons and tons of chicken, fish, scallops. That's the volume of my meat. That's the base of it. Did you ever do that approach or was it always in the context of adding some fats, some oils? I'm just wondering how much that affects how much you actually eat.

Cynthia Thurlow: Well, you have to remember that when I was 30, I was in a hospital working all day long. And I became a parent when I was 34, a second child at 36. And so, I would never have been able to manage the kind of eating schedule that I have now around those responsibilities, because you're lucky if you can eat at all [laughs] when you're working in a hospital and you're rounding on patients. I think that definitely would play a role in it. Personally, I don't do well with fatty meats. I never have. I don't like duck. I tend to lean into lean cuts of meat. I've always been that way. I have a child that's the same way. I think it's just some genetic-- It's this desire, like, we acknowledge. It's not that my body has trouble breaking down fats, because I eat healthy fats, but I don't eat a lot of healthy fats. I can definitely mitigate a carbohydrate load, if I'm exercising. Today, I lifted. And so, I'll probably have some fruit this afternoon after my dinner. 

But with that being said, I would not have been able to eat the way I do now, if I was still working in a hospital and had little kids. I acknowledge that my N of 1, what works for me now is largely because I'm an entrepreneur and I can break my fast whenever I want to. Generally speaking, I don't have to worry that little people are going to stick their fingers in a light socket when I'm trying to eat. Whereas now they largely-- I always say, they're free roaming mini adults right now. They're very self-sufficient for the most part. So, it's hard for me to answer that question because I just don't know. Even when I was in the beginning stages of perimenopause and I noticed that I had that drop off in my appetite, I really think and I haven't been able to get 100% good answer on this, because I've asked a lot of people. I think it's a combination of the muscle changes that impact insulin sensitivity in late 30s, early 40s. That [unintelligible [00:41:28] even though I was always lifting and eating properly, etc. 

And then I do think that there's some loss of estradiol signaling in the gut that may also impact that as well. Again, I haven't gotten great research to be able to back that up. But in talking to other researchers and clinicians, that's been the working hypothesis of why that starts to happen. But we also know that physiologically, we don't need as much food as we get older, whether some people that bothers them or not. I think Mark Sisson, who I know you just interviewed on the podcast as well, he kept saying, “Heck, I don't eat nearly as much food as I used to and I do just fine with--" As a guy, he's like, “I do just fine having one really big meal a day.” He's like, “I'm happy.” So, so many factors.

Melanie Avalon: Yeah, it’s so interesting. It's interesting that you and I are both really similar with that lean meat thing. I still do, basically, lean meats most nights, but probably once a week, I just crave salmon and I'll just do a bolus of really fatty salmon. And I've found that that works for me right now. It's really interesting just how the body changes over time and how your cravings change. 

Cynthia Thurlow: Absolutely. One thing I've noticed and this applies to our audience and listeners, too, is that I can tell where my estrogen levels are by how much cravings I have. I generally don't crave. I crave healthy food, but I don't have cravings that wake me up at night or I don't think about chocolate constantly or something sweet. But estrogen is this cravings modifier, if there's any way to explain it that when our estrogen levels are optimized, it helps with insulin sensitivity, it helps with those cravings, it helps buffer. 

And so, a colleague of mine and I were talking about how we can tell when women are in this perimenopause/menopause state. And a lot of people, they're never full. They might have just eat a meal, but they still don't feel full. And a lot of that can be this diminishing levels of estrogen. And so, really being proactive about getting your levels tested, knowing where they are, and if appropriate, getting some support and that could come in the form of supplements, that could come in the form of hormonal replacement therapy depending on the individual.

Melanie Avalon: Gotcha. So helpful. I so love having you on this show and having your knowledge about all of this. It makes me so excited. I'm like, “Oh, so much good information for people.” Okay, her next question. She says, “I've been doing well with IF. I learned midway through that Splenda and my black coffee and apple cider vinegar with seltzer was a no-no or so called “dirty fast.” I still found success before I learned this, but now, I have saved those things for when I open my window. The days when I did this and I don't open my window for 18 to 20 hours, can this dirty fast still be beneficial? What I mean is, I'll wake up, I'll open my window with coffee and half in half, I'll get sidetracked. I'm a touch ADD. And then several hours later, I've done 18:6, not on purpose. So, do you think my body does not repair like it would without the cream?” This is a good question.

Cynthia Thurlow: I think it's important to keep in the context of dairy as insulinemic. And if you are at your goal weight or whatever metrics you're tracking, you're happy with where your progress has been made, I wouldn't stress and worry if one day out of the week you have a little bit of half and half or cream in your coffee. However, and I'm laughing because I was just at an event this past weekend with Vinnie Tortorich and some other metabolic health people and getting clarification, because some half and half in your coffee for one person might be a teaspoon and for another person, it might be half coffee, half, half and half and that was the joke that Vinnie was telling at this event was that get clarification.

If you're having a teaspoon or a tablespoon, that's probably not going to derail your overall fasting regimen. But if you're derailing your weight loss efforts, because you're consuming a lot of fat, like, what Melanie and I were just talking about, fatty meats. Just fat in general. Fat is calorically very dense. It's great, but too much of any one thing is not beneficial. I think it really depends on what your goals are, but I don't want anyone that's listening to stress that if one day of the week, they decide to have a teaspoon of cream in their coffee that somehow that makes them a bad faster or a dirty faster. It's always in the context of what are your goals, what are you shooting for? If you're weight loss resistant, that's probably not the best choice I would rather that you just use-- 

You can change the flavor profile of black coffee with things like cinnamon, which can boost insulin sensitivity. You can use high-quality salt like Redmond's. And we'll include a link to Redmond’s. I love Redmond’s. They are such great salt. But it can really change the flavor profile, if you're struggling with how bitter coffee can be. But also remember, bitter means that there's a high polyphenol content in the tea or the coffee that you're drinking and you don't want to diminish the net impact of the benefits of those bitter compounds.

Melanie Avalon: That makes me want to go on a really quick tangent. Actually, two thoughts. One about the cinnamon. I'm interviewing on Monday, Ari Whitten. You said you are interviewing him, right? 

Cynthia Thurlow: I think in February. 

Melanie Avalon: Yeah. I haven't read his first book about red light therapy. But his new book is called Eat for Energy and he just goes into all the topics about diet and sleep and it's very supplement focused. So, what type of compounds and supplements can benefit that? It was interesting. His chapter on blood sugar, he goes really hard pushing the cinnamon. I didn’t really considered cinnamon that-- I knew it had those effects on blood sugar, but he really makes the case for having it with every meal, which was pretty interesting. 

Cynthia Thurlow: Like how much in terms of quantity?

Melanie Avalon: He recommends a teaspoon added to meals.

Cynthia Thurlow: Okay, so, it's not a lot. Obviously, when I was doing research for the book, it was something that really stood out as something that could be certainly efficacious. And so, I've recommended people sprinkle some in their coffee, but a teaspoon is a good amount.

Melanie Avalon: And it was interesting, because I do remember you talking about it in the book. And then I was just very, I guess, surprised about the link to which he talked about it. He talked about it and vinegar, which she talks about taking. Oh, since you said it, people are going to really be wondering. [laughs] You don't think or do you think how does cinnamon affect the fast in coffee?

Cynthia Thurlow: Well, it changes the flavor profile, but it's supposed to help improve insulin sensitivity. I don't recall from the research that I looked at so long ago now. It seems it was million years ago. What was the therapeutic amount? I would have to go back and do some digging. But it's certainly not something that is going to break a clean fast. I think that's the distinction our listeners are probably focused on. But it's oftentimes the hook that I get people interested in using black coffee is use Redmond salt or try cinnamon, and almost everyone is able to ease that transition. It just helps curb that bitterness of the plain coffee.

Melanie Avalon: I keep mentioning Mark Schatzker’s book, The End of Craving and I finally just finished both. I was so proud of myself, I read both his other two books in three days. Steak and The Dorito Effect. His books are just amazing. And now, I really want to re interview a carnivore figure like Paul Saladino, or Shawn Baker, or something. Because he doesn't talk about in the context of the carnivore movement or anything. But he makes a really good case for-- Because you're talking about polyphenols and the bitterness and how that might relate. He talks about how basically kids don't often like these bitter vegetables and stuff. And the carnivore movement, people will use that as an example of why we shouldn't be eating plants because they're saying like, “Intuitively, our bodies know not to eat it.” And then we conditioned ourselves to eat it.

When he makes the argument that the body is learning to eat it. It wasn't so much intuition that we shouldn't have eaten it. It was that our body had to learn and adapt in order to get the health benefits from it. I just thought that was a really nicely reframed on that concept with plant toxins.

Cynthia Thurlow: Yeah, and I think the one thing that I fervently believe having gone through a healthcare hiccup is that there was a time posthospitalization that the only thing my body tolerated was meat. But then I got to a point where I started to crave vegetables. I think as your gut heals, you become more tolerant to those plant-based compounds. I truly, truly believe that the average person should be able to eat a variety of macronutrients and not just protein. That's my feeling. I went through nine months of just eating meat. Anytime I tried to reintroduce a vegetable, it was a disaster. No exaggeration. But I think as my gut has healed. And it ebbs and flows. I don't think it's ever going to be perfect. I find myself craving certain things. It'd be interesting to see. I know that Paul is perhaps a bit more outspoken than Shawn. And I've met Shawn in person now. So, I feel I can comfortably say that. But it would be interesting to see what their take would be.

Melanie Avalon: Yeah, I'm just curious. When you were doing the meat only, were you still eating leaner cuts or did you eat fattier cuts?

Cynthia Thurlow: It's funny. I've never and it drives my husband crazy, because I'm sure for everyone listening, all of our meat prices have gone up exponentially. And my husband was grumbling about how the two ribeyes he bought were a third of the price is the filet that he bought for my birthday or whatever piece of fish I'm having. There is a cost difference, but I just feel so much better. I just don't do well with very fatty meats. And just you'll never see me using or eating duck fat fries, or using lard or tallow. Not that there's anything wrong with using those products. I just don't do well. It'll feel like I have a rock in my stomach and it's really unpleasant. I just tend and always have-- always done much better. Throughout my lifetime, it's not something that's just new to this stage of my life, but I've always craved leaner meat. 

Now, we're getting into minutiae. But for me, cartilaginous, very textured meat was just never something that appealed to me and I have a child that's the same way. There's team lean meat. There are two of us. And team fatty meat, they are or two on the other side. And generally speaking, when we buy a cow share it works out beautifully, because [laughs] there are 50% of the house likes leaner cuts and 50% is more flexible. So, it all works out. How about you? Did you always know that you were this way or was it just an evolution as you got more mature?

Melanie Avalon: When I first started doing keto back in the day, I ate fattier meats then and I ate a lot of coconut oil. [laughs] But in the context of a low-carb diet, I was much better with it. When I switched to high carb, I couldn't do the fattier meats and the high carb. It’s like I felt the fat in my system and is very like-- it’s like a feeling. But basically, the next day I just felt more sluggish. I felt I wasn't clearing the fat as much. I just feel better on lean meats. I find when it comes to craving, the thing I crave is the protein. I just crave that lean protein. So, I like fattier meats.

If I were to sit down to have a meal of a ribeye, it would be delicious, but I wouldn't feel as good from it. I don't think and that's why I was curious about when you're doing only meat. If I was doing only meat, I would be very curious. I might be better with fattier meats then, but I haven't done that in a while.

Cynthia Thurlow: No. They sent me home from the hospital telling me to eat a standard American diet. Essentially, a devoid of fiber, highly processed. And my gastroenterologist and surgeon were like, “You know exactly what to do.” And so, I recall it had to be stewed meat or braised meat. It had to be really, really cooked meat. I remember even reintroducing shellfish was a problem. It was a long journey. But I could eat a cooked burger like a champ and I probably ate burgers every day. It was one thing that my body really had a strong desire for, but it had to be a plain burger, nothing on it. Salt and pepper. That was about it.

Melanie Avalon: Yeah. I have one more thought. Oh, so, reading his book, Steak, where he basically travels all over the world. I learned so much and tried steak in all these different countries, and tried to figure out what makes a good steak. And after reading that book, I was craving a steak. I have quite a few steaks in my freezer from ButcherBox. I will say, “Oh my goodness.” Have you had the ButcherBox filets?

Cynthia Thurlow: Mm-mm.

Melanie Avalon: They're really, really good. I love carpaccio. I pulled it out and I was like, “I wonder if I can make my own carpaccio from this?” I sliced it rare and it was so tender, it was so delicious. So, plug for ButcherBox. They have really good steaks. And our link for them is butcherbox.com/ifpodcast. I'm not sure what the offer is right now, but they usually have really good offers going. I'm excited to interview him, but I think his takeaway was that the thing that most affects flavor, it's funny how just how different the different ideas are in different countries about what makes a good steak. The USDA prime concept is just about the marbling. It's nothing about the flavor. I don't know, I think it's very misleading as far as what makes a good steak. 

And then, wait, there was one other fact. Oh, this blew my mind. The criteria for Angus steak is so arbitrary that you would think it would be from the Angus breed, but it's not. They do it based on-- The criteria is like, “Is the cow black?” Because most Angus cows are black. And then all these other criteria, but none of it is actually is it an Angus steak. So, there's all of these crazy nuances in the steak world that just blew my mind. I was like, “Oh, wow, can't trust a label.”

Cynthia Thurlow: No, I think that goes for anything here in the United States, [laughs] unfortunately.

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Melanie Avalon: So, her next question. She says, “Due to my health history, I get bloodwork frequently. My glucose is often, high 109. I don't understand. It is frustrating, because I don't eat processed foods much at all. Could alcohol affect this? Before you answer that, if I'm being honest, I'm drinking more now than ever during COVID-19, but I mostly clear liquor, tequila, and vodka, and yes, wine several days a week. If my sugar is up, can I still be successful at IF? This is very confusing to me?”

Cynthia Thurlow: Well, clearly, it sounds like you're in perimenopause. You're going to be prone to less insulin sensitivity. If you're fasting blood sugar's 109, that's high. I would be asking for a fasting insulin. I would want to know an A1c, I want to look at inflammatory markers, like, a high-sensitivity CRP, and you would be an ideal person to have a glucometer or continuous glucose monitor without question.

A lot of things impact blood sugar, sleep quality, stress management, overexercising, inflammatory foods, gut health, toxins. I would say at a bare minimum you need a deeper dive. But a blood sugar of 109, if it's been that level multiple times, it's a wakeup call that you're setting yourself up to develop some degree of insulin resistance. It's time to have an honest conversation. If you're still eating gluten, and grains, and dairy, and alcohol, and processed sugars, all of those things can exacerbate insulin resistance. So, it's really a wakeup call.

Melanie Avalon: I agree. And just speaking to the alcohol piece specifically, typically drinking alcohol in the fasted state will actually lower your blood sugar. But if you're having alcohol with your meal, it also might lower the blood sugar effect, but it's very individual. For some people, it might have the opposite effect because the body's processing the alcohol. And so, the glucose from your meal is staying elevated in your bloodstream. Again, it's a thing where you're going to have to monitor with a continuous glucose monitor to see how it's affecting you specifically, but agreed with Cynthia that it's concerning. So, definitely something to look further into.

Not to put a Band-Aid on it with a supplement, but something like berberine might also be helpful supplement to integrate into your protocol. She also says, “She thought she was in perimenopause, but then she had a full-blown cycle” and she just wanted to point that out. I think she was saying this, because I cut down this question a little bit. But Gin had an experience, I think where perimenopause and the definition of it and then having thinking you're done, and then you're not, and so, she was referring to that. Do you see that a lot with your patients, by the way, Cynthia, people who think they're at a certain point with perimenopause or menopause and then have a surprise?

Cynthia Thurlow: No, not all that often, because so, let me backtrack. Over the past two years without getting controversial, if anyone received a vaccine for a virus that we have been in a pandemic over, I'll just put it that way. I've seen a lot of women in menopause that have started menstruating, again. I've seen women that are peak cycling years that have gone on to have months, and months, and months of irregular shorter, longer cycles. So, certainly, if you fall underneath those parameters, that may be directly related to the vaccine. Let me just put that out there. 

Number two, generally, if you've gone 12 months without a menstrual cycle, you are menopausal. If you suddenly start bleeding after that 12 months that absolutely warrants seeing your GYN or your internist to make sure there's no other reason to explain why that would happen. If someone is not yet in menopause, and they have 18 months without a menstrual cycle, and then they get one that's obviously different. This is a question that is best directed to your healthcare professional. But again, if you're 51 years of age or older, that's the average age in the United States for menopause. And you have not had a period for 12 months or longer and you suddenly get a period, you need to let your GYN know that requires follow up with them. And it could turn out to be completely benign, however, you need to make sure it's not related to another issue.

Melanie Avalon: She has one last question. She said, “She's not been able to drink diet soda or regular soda since chemotherapy, which is a blessing in disguise. And she also can't consume anything with artificial lemon or lime. They all give her a horrible aftertaste. But she can have cherry or orange Tootsie Rolls, which is strange.” She says, “She knows we're not doctors, but do we have thoughts on why.” I will just say, I don't know, but I will say, after reading, I mentioned it already. But in particular, The Dorito Effect and learning the mind blowingness about all of these artificial flavors, and how they're created, and what they are, and what they do, and how they signal to our bodies. It doesn't surprise me that going through something like chemotherapy, I don't know what happened, but it has some effect and how your body is interpreting these flavors. So, that's not surprising to me.

Cynthia Thurlow: Very common for patients that have gone through chemotherapy to develop. Sometimes, it can be transient, short-term, but also long-term taste preferences. And I think it would be highly dependent on the type of chemotherapy that you received. Whatever chemo toxic agent you received, some of them may have more lingering long-term effects than others. That would be my first guess. But certainly, something to discuss with your oncology team. If this is someone else that's listening that's experiencing this, I have someone on my team who very openly talks about being aggressive cancer thriver. That's how she refers to herself. And I fervently agree with that that she definitely had a period of time transiently, where she had some taste preferences, or things that tasted metallic or cottony in her mouth that ever resolved. But I think it's largely dependent on the type of cancer you're being treated for and the type of chemo toxic drug that you received.

Melanie Avalon: Thank you. That was so helpful. I did not know that. [laughs] And also, Doreen, sending you lots of love with that whole situation with your cancer and we're happy that you caught it early. And it sounds like the chemotherapy is going well. So, very happy for you with that. She says, “I want to thank you, ladies. I feel blessed beyond words to have been able to include you in my daily life. Love and light.” Oh, she goes by D. So, thank you D for your question, which apparently was our episode. 

Cynthia Thurlow: It was a long question, but our next episode, we're going to get a couple for sure fit in. 

Melanie Avalon: Yes. The show notes for today's episode will be at ifpodcast.com/episode279. Those show notes will have a full transcript. So, definitely check that out. If you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. You can follow us on Instagram. We are @ifpodcast, I am @melanieavalon, Cynthia is @cynthia_thurlow_. And again, a reminder to enter the giveaway for some goodies from Cynthia. If you have her book, Intermittent Fasting Transformation or if you don't, if you get it, which you should, just leave a review on whatever platform you bought it on. It's super easy to do and just send a screenshot of that to questions@ifpodcast.com to enter to win and this is US continental residents only. Yes, I think that is all the things. Anything from you, Cynthia, before we go?

Cynthia Thurlow: No, thank you. Keep those great questions coming. Obviously, today was an unusually long question, but we will definitely get to several on the next episode we record. 

Melanie Avalon: Awesome. Well, I will talk to you next week. 

Cynthia Thurlow: Sounds good. 

Melanie Avalon: Bye. 

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and recomposed by Steve Saunders. See you next week.

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