Search Results for: ken brown

Support!

Help Make The Intermittent Fasting Podcast Possible!

Hi Friends! We put a ton of time and energy into researching and producing The Intermittent Fasting Podcast. You can help support us on Patreon! Every dollar helps!

Jan 15

Episode 300: AMA! Sleep, Whole Foods, Musical Theater, Bloating, Parasites, Botox, Anti-Aging Skincare, Laser Hair Removal, Favorite Books, And More!

Intermittent Fasting

Welcome to Episode 300 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

BUTCHERBOX: Grass-Fed Beef, Organic Chicken, Heritage Pork, Wild-Caught Seafood: Nutrient-Rich, Raised Sustainably The Way Nature Intended, And Shipped Straight To Your Door! For A Limited Time Go To butcherbox.com/ifpodcast And Get The New Year Bundle For Free Plus $10 Off When You Sign Up Today. That’s A 14 Oz Pork Tenderloin, 2 Lbs Of Ground Turkey, And 4 Top Sirloin Steaks Free In Your First Box!

BLISSYGet Cooling, Comfortable, Sustainable Silk Pillowcases To Revolutionize Your -Sleep, Skin, And Hair! Once You Get Silk Pillowcases, You Will Never Look Back! Get Blissy In Tons Of Colors, And Risk-Free For 60 Nights, At Blissy.Com/ifpodcast, With The Code ifpodcast For 30% Off!

Athletic Greens: 75 high-quality vitamins, minerals, whole-food sourced ingredients, probiotics, and adaptogens in one delicious scoop! Get A FREE 1 year supply of immune-supporting Vitamin D AND 5 FREE travel packs with your first purchase at athleticgreens.com/IFPODCAST.

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get The New Year Bundle For Free Plus $10 Off When You Sign Up Today. That’s A 14 Oz Pork Tenderloin, 2 Lbs Of Ground Turkey, And 4 Top Sirloin Steaks Free In Your First Box!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

IF Biohackers: Intermittent Fasting + Real Foods + Life

 Listener Q&A: Nicole - What’s one piece of advice you’d give to someone looking to get healthier? 

Listener Q&A: Samantha - I know you are a musical theater fan, what is your favorite musical?

BLISSY: Get Blissy In Tons Of Colors, And Risk-Free For 60 Nights, At blissy.com/ifpodcast, With The Code IFPODCAST For 30% Off!

Listener Q&A: Alani - What are your tricks for keeping your stomach from puffing out?

Listener Q&A: David - Have either of you taken a DNA stool analysis for parasites?

Episode 296: Berberine, Insulin Sensitivity, Glucose Control, Gut Health, Liver Health, Body Recomposition, AMPK Activation, Cholesterol Control, And More!

Listener Q&A: Amy - Loved last episode where you both admitted you color your hair without shame in not using cleaner options. I would be curious what other things are you willing to “bend” the rules for?

ATHLETIC GREENS: Get A FREE 1 Year Supply Of Immune-Supporting Vitamin D AND 5 FREE Travel Packs With Your First Purchase At athleticgreens.com/ifpodcast.

Listener Q&A: Damon - Laser hair removal, is it worth it?

Listener Q&A: Kimberly - What are your top 3 book recommendations besides your own?

Listener Q&A: Danielle - What is your favorite holiday tradition?

Listener Q&A: Lesley - I work at HOTWORX 24 hour infrared fitness studio. What do you think about a 3d workout? Heat, exercise, infrared sauna?

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 300 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I’m Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting and Wine. I’m here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: A 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it’s that time and get ready for The Intermittent Fasting Podcast. 

Hi friends, I’m about to tell you how you can get a 14-ounce heritage-breed pork tenderloin, 2 pounds of sustainably raised ground turkey, and four grass-fed top sirloin steaks, all for free, plus $10 off. Yes, all of that incredible meat, plus $10 off, all for free. We are a bit obsessed with a company called ButcherBox, which is always in season. Some of my favorite meals that I had throughout the holiday season were fantastic meat and seafood from ButcherBox. Now with the new year, it is time to celebrate with only the very best of the best when it comes to meat and seafood that you put in your body, as well as meat and seafood that helps support our planet and the environment.

They make it so, so easy to get high-quality humanely raised meat that you can trust. They deliver 100% grass-fed, grass-finished beef, free-range organic chicken, heritage-breed pork, that’s really hard to find, by the way, and wild-caught sustainable and responsible seafood shipped directly to your door. When you become a member, you’re joining a community focused on doing what’s better for everyone. That includes caring about the lives of animals, the livelihoods of farmers, treating our planet with respect, and enjoying deliciously better meals together. I did so much research on ButcherBox, you can actually check out my blog post all about it at melanieavalon.com/butcherbox.

All of their beef is 100% grass-fed and grass-finished and they work personally with all the farmers to truly support the regenerative agriculture system. I also did an interview with Robb Wolf on my show, The Melanie Avalon Biohacking Podcast, all about the massive importance of supporting regenerative agriculture for the sustainability of not only ourselves but the planet. This is so important to me. I’ll put a link to that in the show notes. The value is incredible. The average cost is actually less than $6 per meal and it’s so easy. Everything ships directly to your door and it is so delicious. I love carpaccio for example. The ButcherBox steaks are incredible for that. That’s how you know it’s good steak when you can eat it rare like that and ButcherBox has an incredible offer for our audience.

You can get the New Year bundle for free, plus $10 off when you sign up today. That’s a 14-ounce heritage-breed pork tenderloin, 2 pounds of sustainably raised ground turkey, and four grass-fed top sirloin steaks, all for free, in your first box. Sign up @butcherbox.com/ifpodcast and use code IFPODCAST to claim this offer. Again, to get a 14-ounce heritage-breed pork tenderloin, 2 pounds of sustainably raised ground turkey, and four grass-fed top sirloin steaks, all for free, plus $10 off, sign up @butcherbox.com/ifpodcast and use code IFPODCAST to claim this offer. We’ll put all this information in the show notes.

One more thing before we jump in, are you fasting clean inside and out. So, when it comes to weight loss, we focus a lot on what and when we eat. It makes sense because these foods affect our hormones and how our bodies store and burn fat. But do you what is possibly one of the most influential factors in weight gain. It’s not your food and it’s not fasting. It’s actually our skincare and makeup. So, as it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disruptors, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we’re using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream.

And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup may be playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That’s because ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking. And the effects last for years. 

Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means when you put on some conventional lipstick, 30 years later maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves. That’s why it’s up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life. And their makeup is amazing. Check out my Instagram to see what it looks like. Tina Fey, even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies and so much more.

You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my Clean Beauty email list. That’s at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list, so definitely check it out. You can join me in my Facebook group Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well.

And lastly, if you’re thinking of making Clean Beauty and Safe Skincare a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It’s sort of like Amazon Prime for Clean Beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code CLEANFORALL20 to get 20% off your first order. And we’ll put all this information in the show notes. All right, now back to the show.

Hi, everybody, and welcome. This is Episode number 300 of the Intermittent Fasting Podcast. Very exciting milestone episode here. I'm Melanie Avalon, and I'm here with Cynthia Thurlow. How are you, Cynthia? 

Cynthia Thurlow: I'm doing well despite navigating travel back to small airports. I was laughing/texting with you last night sharing all the insights I was gleaming being stuck in an airport for 7 hours with a long delay. 

Melanie Avalon: Yes, were talking about the food options, healthy or not, fasting or not in airport layovers, so I'm glad you survived. 

Cynthia Thurlow: Yeah, I know it's funny. I'm such an observer as an introvert, like, I just love to people watch. The behaviors that I was watching yesterday intermittently between reading a book, listening to a podcast, reading another book, binging on something on Netflix was just the behavioral patterns. I think people feel a lot of pressure to eat constantly when they're in airports, and I just find that all super fascinating. I think I was chronicling how it doesn't matter what airport I go to. I can generally get a naked burger and a salad and that's typically what I do. 

Actually, the waiter yesterday, it was funny. I got off my flight from LA and Chicago and I was like, okay, plenty of time. I have two and a half hours, I'll be great. I went to a restaurant, got my burger, read a book. I was totally by myself. I was totally in my zone. And then get to my gate and then we realized we've got, like, mechanical problems. I guess pilots and stewards, stewardesses are only allowed to fly for a certain amount of time every day because of the mechanical delay it turned into. We had a different flight crew. It was like a seven hour instead of a two and a half hour time in between flights. I was texting with Melanie and I said, and then, it's not a good sign when United rolls out the cart of snacks. And the cart of snacks was gone in about two minutes. It was amazing. People were clearly, “starving.” But it was hilarious to kind of watch all this unfold. So, I'm just grateful to be home and the fact that I got a decent amount of night's sleep, and it's my last business trip of the year, so no more traveling for a while. 

Melanie Avalon: Yeah. I feel like it definitely speaks to just how much well, A, we're inundated with food and food advertising and accessibility and also how food is really just a pastime. Like, if we're bored, I'm sure people were hungry as well. It's a comfort. It fills the gap of boredom. 

Cynthia Thurlow: Absolutely. I get that, there's no judgment on my part, the psychology behind the way people eat. That's why I always say, like, if you eat enough protein, you're just too full. Even if I had endeavored to eat the bag of Cheez-Its or Goldfish or whatever myriad of stuff they had, I was like, I just grabbed a bottle of water because I was so dehydrated from traveling that I was like, I'll just grab the water, and I'll just try to stay hydrated, and we'll just go from there. 

Melanie Avalon: Yeah, I always fast when traveling. If it was, like, that situation where it was a really long layover, honestly, I would probably still fast. I would probably turn it into a longer fast moment. Just because I don't feel comfortable with lots of food in me and trap. It makes me sluggish and--

Cynthia Thurlow: Yeah, definitely. I wore-- so people will probably be humored. Like, I've got a whole wardrobe of things I wear when I travel so that I can wear layers. So, I'm never cold, because traveling through Chicago, it was actually the airport was quite cold, which actually wasn't a problem. I was like, okay, I got a sweater. I'll just put that on. I had Spanx, like, leggings on all day because they're super comfortable. They weren't comfortable at, like, hour 18. They were definitely [laughs] when my husband picked me up, I was like, there's too much compression on my stomach and I've been doing a lot of sitting. He was like, “What are you trying to tell me?” I said, “You know how I talk about like there are specific things I wear when I travel. This is not the outfit. If I'm doing more than like 14 hours of travel, there's just too much compression on my stomach.” My stomach was like not happy with me at all. 

Melanie Avalon: I can't wear Spanx at all. That's how you don't have GI issues. 

Cynthia Thurlow: Yeah, they're definitely different. They're super comfortable actually. It's just that amount-- it would be like trying to wear like, Lululemon tights all day long and traveling. It's a lot of compression on your gut. 

Melanie Avalon: Well, speaking of--

Cynthia Thurlow: Probably TMI. This is a good segue into our Q&A because it's like there may be a little TMI today. 

Melanie Avalon: So, for listeners, we really wanted to celebrate Episode 300, quite a milestone. There're a lot of episodes, I think actually for every, well, there's only been two other 100 miles markers. So, Episode 100 and Episode 200. I think for both of those we did an AMA episode. So, continuing the tradition going to do and ask me anything. We got so many amazing questions that we're anticipating. This will probably be a part one, part two, maybe a part three. We'll see how it goes. We got so many really great questions in the Facebook Group which people should join, which is IF Biohackers: Intermittent Fasting + Real foods + Life. That's my personal Facebook group. I asked in that group for ask me anything questions and we got so many. What I did was I divided them into categories. I think we'll just alternate between more personal ones, more health and wellness-related ones. We'll just see where it goes. I have a lot of questions. I'm very excited about this. So, Cynthia, should we jump in?

Cynthia Thurlow: Yes, we should. 

Melanie Avalon: I'm thinking we might because I have, like I said, it's by categories, so I might alternate with the lifehack ones and the likes and things like that with the more health related. Here's a good lifehack that's kind of both. And this comes from Nicole. "What's one piece of advice you'd give someone looking to get healthier?"

Cynthia Thurlow: Oh, gosh. I think and it's funny, I was out in LA and I did four podcasts and pretty consistently the one for me is sleep as a foundational element to health for anyone at any stage of life. I would say really investing in high quality sleep and really starting with the foundations. Not necessarily rushing to a supplement, but doing the things that we know improve sleep quality, daily exercise, light exposure in the morning, getting off electronics, wearing blue blockers, making sure you don't eat two to three hours before bed unless you're a unicorn. I think those are the things that I really think about. I think we like to make things very complicated. I always say before you even think about adding a supplement, make sure you're doing the sleep hygiene pieces. Sleeping in a cold, dark room. I sleep with a sleep mask. I keep the thermostat at 65 degrees. In fact, it was funny when I came home last night, it was 69 degrees on our second floor. The first thing I said to my family was, “Oh, we're going to drop the thermostat because I need it at 65.” Everyone was like, “We've been sleeping at a much warmer temperature.” And I'm like, “I can't do that.” So, I would probably say focusing in on sleep first and then adding supplements if you still need additional support. How about you, Melanie?

Melanie Avalon: That's a good one. I'm actually surprised I didn't think of sleep as the first thing. Whenever people ask me what's the most important thing for me to focus on, I think I normally do say sleep. So, I'm really glad you tackled it. I was thinking on the diet side of things and I was really torn between eating whole foods not the store, but like, foods in their whole form, because that's macro-agnostic, but I just think if we just return to eating real food, that can have a profound effect on people's health. I was torn between that and fasting [laughs] surprise, but I actually think I would go the whole foods route.

Cynthia Thurlow: And I think that's really important. I am a huge advocate of saying that it all starts with food, and I see so many people that are quick to embrace the latest fad irrespective of what it's leaning into. I just remind people, if we just keep things simple, focusing in on sleep, eating as nutrient dense foods as you can, I think that's really, really helpful.

Melanie Avalon: Yeah, I obviously think so as well. I think between those two, honestly, if somebody's not addressing those two things and then they address those two things, I think the profound effect it would have on so many people's health would be crazy. You don't even have to be really specific or do like a certain type of diet, but that combined with the sleep, very powerful. 

Cynthia Thurlow: Yeah, absolutely. Keep it simple. I mean if there's one tried-and-true message that I think both of us discuss consistently is keep things simple because if we try to make too many changes all at once, it's overwhelming. It's hard to stay, I hate to use the word compliant, but that's the easiest way to put it. It's hard to be consistent when you're trying to change five things at once. That's what I think most people do. I mean, I certainly have been guilty of it myself, but pick one thing at a time and really lean into it and master it and then move on to something else. 

Melanie Avalon: Okay, here's the fun one and she addressed it to me, but we can both answer it. It's from Samantha. She said, “Melanie, I know you are a musical theater fan. What is your favorite musical?” 

So, I'll go ahead and answer that. I think I might have answered this on another AMA. This question, I always feel mischaracterizes me because my answer is musicals that, it sounds like a cop out, like, “Oh, she doesn't watch musicals because she's listing,” the one that everybody says, but I promise you I listen to so many musicals. But there's a reason that these two musicals are what they are, which is Phantom and Wicked. They're just so amazing. But then my runner ups are next to normal Jekyll & Hyde and Hamilton. I know she said your favorite, but there're so many, and then I have, like 50 million more. How about you, Cynthia? 

Cynthia Thurlow: A few of those I've seen. I grew up in New Jersey, and so my mom really prioritized taking me to Broadway, and so I did that throughout my childhood. For me, I would say Rent I loved. I mean, I still can listen to the music Wicked, I saw that on Broadway with the original cast just by complete happenstance.

Melanie Avalon: Whoa. Okay, I have a question. Oh, I have a question. Did you see it because when it first came out, it was a bomb like it didn't-- Did you see it before it got famous? 

Cynthia Thurlow: No, I saw it afterwards, it was with Kristin Chenoweth and--

Melanie Avalon: So, there was fanfare surrounding it when you saw it, because when it first came out, it did not take off. 

Cynthia Thurlow: Yeah, because it was 2005/2006 somewhere around there, because I was up there for a medical conference, and my girlfriend was like, “We should go see this play.” And I was kind of like, “Okay.” I had no idea what it was really even about. I just saw Hamilton, and I've been wanting to see Hamilton on Broadway for, I don't know, five years and with the pandemic that kind of nixed our ability to do that and that was amazing. To me, I have so much respect and reverence for people that work in the creative arts. I am not the least bit like, don't ask me to sing, don't ask me to act or dance in front of other people. I would be so embarrassed. I'd want to crawl in a hole, but I love to watch really talented people perform. I just have so much respect and admiration because it's so very different than where my zones of genius are.

As I was sitting there watching Hamilton with my husband and my boys, and I was like, “God, I feel so lucky to be in this zone of greatness.” Like, watching these really talented actors and actresses do what they do best.

Melanie Avalon: That is the exact way I feel. 

Cynthia Thurlow: Yeah. I'm the kind of person, I actually get emotional when I'm watching people when they're really, really good at what they do whether it's dancing or singing or a play. I get a little like teary. It's almost like out of total admiration that I'm witnessing their greatness. 

Melanie Avalon: Yeah, no, I feel the same and actually, I had a similar experience. I saw the original cast of Next to Normal. It was one of those things where I went in like you to Wicked like I didn't really know what I was going into and then I was just blown away. Ah, love musicals. 

Hi friends. Are your pillowcases antiaging. I'm about to tell you how to get 30% off my favorite silk pillowcases ever. I am obsessed with a company called Blissy. It's really the thing that you didn't realize you needed until you experience it. You're just like, where has this been all my life. If you've been listening to this show, you might remember back in the day when I was trying to convince my old cohost Gin Stephens to get silk pillowcases to revolutionize her sleep. That was even before I found Blissy. You guys also know I am obsessed with sleep. Well, you can set yourself up for better sleep this year with Blissy's award winning 100% mulberry silk pillowcases. And yes, they are sustainable, I asked the company.

So, why do these pillowcases support your sleep? And why are they antiaging? First of all, they are cooling. Blissy's pillowcases actually regulate temperature to keep you cool at night. Honestly, the entire pillow is cool to the touch. You know how often you have toss and turn to find the cool side of your pillow, or flip over the pillow because it gets warm. That doesn't happen with these pillowcases. It's crazy. We know that sleep temperature drastically affects sleep quality. They also help your hair and skin. Yes, silk is what is best for your hair and skin. It reduces frizz, tangles and prevents breakages. That is because it keeps the moisture in your hair and keeps your skin care products and natural moisture on your skin, unlike cotton does. So, with Blissy you can say goodbye to wrinkly, dry and flaky skin in the morning and wake up with healthier, shinier hair. I promise you that is actually the original reason I started using silk pillowcases years and years ago was for the hair benefits.

And because Blissy pillowcases are made of 100% mulberry silk, they are naturally hypoallergenic. You sleep more comfortably without itching or rashes. So, sleep cooler, better hair and skin, hypoallergenic. That's why these are definitely antiaging pillowcases. If you're familiar with silk pillowcases, you might have had the moment, like me, where you get them and then you look at the care instructions on the tag and it says don't wash them which is very confusing, [laughs] but not with Blissy. They have solved this problem. They are the highest quality silk, yet they are still machine washable and durable. I am obsessed. These pillowcases make the best gifts. I gave them to so many people over the holidays. Valentine's Day is coming up. Why not give the sexy gift of better sleep, plus, they come in adorable gift ready packaging that your friend, family, or lover will be sure to appreciate. Everybody loves them. They have a ton of different prints and colors, and they make great gifts because there's an option for literally anyone. Yes, men love them, too. 

Blissy has over 1 million raving fans and you could be next. You can try now risk free for 60 nights. Yes, that is two months at blissy.com/ifpodcast and get an additional 30% off that's B-L-I-S-S-Y.com/ifpodcast and use the code IFPODCAST to get an additional 30% off. Your hair and skin will thank you. By the way, Blissy was the 2021 Good Housekeeping Winner for best bedding and has been featured in Oprah Daily, Alert, Glamour, POPSUGAR and many more. Everybody's talking about it, and there is good reason for that. I'll put all this information in the show notes.

Here's another one and this kind of relates to what we were talking about earlier, “What are your tricks for keeping your stomach from puffing out? Do you use Spanx for that?”

Cynthia Thurlow: I mean, I don't generally have issues related to bloating. I'm probably blessed genetically with some of this on my own. Obviously, I no longer get a menstrual cycle, but when I did, when I was sometimes right before my period, and I would feel bloated. Spanx is great for that. There're different layers of levels of Spanx, so it's not all so constrictive you feel like you're going to die. For me, quite honestly, it's finding a balance between protein and vegetables. This is going to sound odd, but I'll kind of layer this in. When I'm eating a very protein dense diet and I'm eating cooked vegetables, I have little to no bloating, but if I go on a salad binge, like, I mean, a lot of raw vegetables, that can sometimes give me a little bit of bloat. I have to kind of moderate that. 

I got most of my bloating quite honestly from gluten and dairy. And now that I don't have those in my diet, it's not as much of an issue. But I can tell you, and I know we have a parasite question in this Google Doc that we're looking at when we talk about parasites. I will tell you about my bloating issues, but generally speaking, not a lot. I think a great deal of that has to do with dietary choices and not overeating. Like, I feel so miserable if I've overeaten or if I've eaten too much food that I just-- I know where my sweet spot is and if I'm kind of leaning into the protein and cook vegetables, I do really well. How about you? 

Melanie Avalon: Yeah, well, first thing I wrote was just suck it in. [both laughs]

Cynthia Thurlow: Well, I mean, here's the other thing before you say the next thing. A lot of people when they talk about bloating, it's really not bloating. It's because their core is not very strong. So, again, I think some of this is just probably innately how I was made. I've always had a pretty strong core and I've always done Pilates. I've always done a lot of core focused work. If you think about your rectus abdominis and your obliques and all these muscles that work together to kind of hold you in and hold you up, if they're not strong, that can contribute to people perceiving that they're having bloating, when it's really just they have muscles that need a little bit of work, if that helps. 

Melanie Avalon: So that's interesting. That writes me of two things. One, I have this childhood memory, I don't know how old I was, I was probably like nine or ten and some aunt commented on my stomach sticking out.

Cynthia Thurlow: Oh, well, sometimes kids have like lordosis and it's not even that their stomach sticking out, it's they have like a swayed lower back. It has nothing to do with the belly sticking out.

Melanie Avalon: That's what the aunt said. She was like, “Oh, this runs in the family or something.” But do you know how traumatic that is to be told that.

Cynthia Thurlow: People sometimes are thoughtless. I just don't realize they're filters off. It's like you could have said that or just not said that and we would have all been okay.

Melanie Avalon: Not to like a nine or ten-year-old, but what's interesting is, I think this is a fun little also lifehack, I feel like a good way to get a good core workout. So, I saw Trans-Siberian Orchestra recently. I realized I have my crazy concert outfit, which is like this really massive spark-- It looks like a dress, but not really because it's a two-piece, so it's like midriff bearing and then it's this massive sparkly dress. You can see it on my Instagram. It's incredible. In any case, I feel like it's a good hack to get a stomach workout if you wear something like that out, because then you're consciously holding in your stomach, like the entire time, unless you forget. But my first tip was just suck it in.

My second tip [laughs] was based on the digestion and finding the diet that works for you. For me, digestive enzymes are game changers for that. Finding a digestive enzyme supplement that works might help. Also, like Cynthia was saying finding the dietary combination a lot of people-- for me low FODMAP works really well and that keeps me not bloated. Also, oh, here's one. If you go carnivore for a lot of people your stomach will probably get very flat. I experienced that. Whenever I do experiment with a time of just meat, there's zero bloating. 

Cynthia Thurlow: Well, when and if we get to the parasite question in this episode, we can talk about this because that's how I knew something was very wrong and very, very wrong. I always say going back to an anti-inflammatory, like a real anti-inflammatory diet can sometimes be partial carnivore or carnivore for a couple of weeks can really be hugely impactful. But I always say just perceiving you have bloating is very different than looking six months pregnant bloating. There's that continuum that I think is important to identify. 

Melanie Avalon: I'm starting to think this might be like a four-part episode. It'll be like the AMA month. It'll be like January, the AMA month. [laughs] Okay, so, David, "Have either of you taken a DNA stool analysis for parasites?"

Cynthia Thurlow: Yes, multiple times. I have had parasites, more benign parasites, like Blastocystis, which is very common. Let me just back up and say, it is very common to see parasites even in first world countries. Don't think that, oh, you haven't traveled, there's no way you've been exposed. It's really more about exposure and susceptibility. I think that the really exciting story to share is my Morocco tales, because that's where I got the worst food poisoning of my life. I had probably an acute parasite issue that morphed into a fairly significant parasite issue and we believe is a reason why I ended up developing a ruptured appendix and being so sick and necessitated. So, let me back up further and say that you can have an acute reaction to a parasite infestation and then you can have chronic parasitic infections. I have had both and the second one was harder to tease out. 

But I'm grateful that I have amazing colleagues who, as soon as I told them my symptoms, they were like, you definitely have X. I kept saying, “No, no I've done a GI map and it didn't show it.” And I ended up going through a parasite expert who puts your stool, your poop in a slide and looks at it under a microscope. Microscopy, which is pretty important, and I indeed had two parasites, and I had Candida and I had E. coli. Within one dose of antibiotics, I felt like a different person. There was no question there was something wrong with my gut because I had tremendous bloating. By the end of the day, I looked six months' pregnant, which is a problem because there's no way I'm pregnant. I had horrible, horrible gas, like, distinctively bad foul-smelling gas, and I just didn't feel good.

It didn't matter how much I slept, what I ate. It was like as soon as I ate it started this whole bloating, gas, loose stools situation that went on for probably a month until I had gotten the stool results back. It was actually an expensive test that's done out of a lab in New Mexico, But for me, life changing. I didn't want to go on it. I literally had to take one day of one antibiotic to kill this thing. I was so grateful that I had something that could treat it. 

Melanie Avalon: Do you know what antibiotic it was? 

Cynthia Thurlow: As I am saying this. So, this is Giardia. Giardia is generally transmitted in water. If you have like, as an example, doesn't mean everyone has a well. If you are exposed to contaminated water or people that have Giardia and they don't wash their hands after they go to the bathroom, you can get exposed to it. So, I took tinidazole. It's T-I-N-I-D-A-Z-O-L-E. 

Melanie Avalon: Wow. It only took one and it knocks it out? 

Cynthia Thurlow: Yeah, it's like a large bolus of antibiotic. My husband had to be treated, too, even though we didn't test him. Parasites can be transmitted in saliva and sexually. I've done a lot of interesting international travel and this female physician friend of mine was adamant, as soon as I talked to her, she was like, I don't even need to test you, you have Giardia, but I didn't just have Giardia. I had another friend too, [laughs] so it was pretty disgusting. It was like literally one dose of medication and the next day I felt 1000% better. 

Melanie Avalon: Wow. That's crazy. 

Cynthia Thurlow: Yeah. Aren't you glad you asked it? I saw that question and I was like I will be happy to answer that question because conventional testing for ova and parasites does not always pick this up. Even the GI Map, which I clinically believe is a really really good test, never picked this up. 

Melanie Avalon: Yeah, that's one of the things. Because I've done parasite stool testing, I mean, probably multiple times. Honestly, I know some of them have been negative. I don't even remember if some of them pick something up. I just remember at one point I was working with a practitioner and it came back negative. But then he was like, “All your symptoms match parasites.” And he said most people have parasites. He had me do a course of Alinia, are you familiar with that one? 

Cynthia Thurlow: I am not personally, but only because I myself have not written a script for it.

Melanie Avalon: Okay. Yeah. He said that it was like a game-changing anti-parasite drug that revolutionized so many of his patients and it probably helped. It was during the time when I was at a really not feeling well place health wise, so I don't really know what was doing what, but I did do that. I also have done, I've talked about on the show before, have you taken Mimosa pudica? 

Cynthia Thurlow: I have not. I've taken a lot of stuff, but I've not taken that. 

Melanie Avalon: Oh, my goodness, Cynthia, and listeners, I know they've heard me talk about it before. Okay, this stuff, I should probably do another round of it. So, it doesn't kill anything. So, you don't get detox effects because it's not making anything angry. It's a very sticky gelatinous, something from some tree or something. The thing that's confusing about it and the reason I'm being so hesitant, like you can look it up, people have pictures. If you put it in water, you'll see that it forms a really long mucusy string. So, you end up passing that regardless. It's going to look like you're passing parasites regardless because it just looks like that after it comes out of you. But it will grab things and I swear to you, [laughs] the things that have come out by taking that were shocking to the point where I was like, I can't keep taking this is too scary. 

And that's the response. There are like groups dedicated to this basically, but it's super cheap. You can get on Amazon, Mimosa pudica and maybe I should make this someday. It's crazy, that's all I can say. It's crazy. 

Cynthia Thurlow: Yeah. I think what's interesting as a traditionally trained provider, it's always amazing to me that there are a lot of herbs and antimicrobials including berberine as an example. It's a potent antimicrobial that can be very effective at getting rid of pathogens and they don't have the same detrimental impact on the gut microbiome that traditional antibiotics do. Let me be clear, there was no other option for me. There was no antimicrobial that was going to kill what I had because it was so substantial and significant. I'm like, I will be forever grateful that I got some validation. But having said that, it's just nice to know that there's a lot out there that we're still learning about herbs and other potent combinations of different ingredients that can be very beneficial at killing off what does not belong. If you need antibiotics to kill off what does not belong, there is no shame in that either. 

Melanie Avalon: Yeah, and I think the thing I really want to emphasize about Mimosa is it's not killing anything. It's literally just physically grabbing stuff out of you. That's why people don't get the detox effects like I mentioned. That's why you can actually see an entire thing. It's crazy. [laughs] It's for parasites specifically. Yes, I agree 100% with what you're saying about. There are so many options and alternatives out there and it's nice that there's more and more awareness about it. Especially like with the berberine, people think about that primarily for blood sugar control. We talk about this in Episode 296 with Scott Emmens, I'll put a link to it. It was actually first used in 3000 BC, which is so long ago, and not for blood sugar control. They didn't even know that was a thing back then, but for gut inflammation and yeah, GI health, so crazy.

That actually reminds me of another question on here because I'm not saying antibiotics are bad, but they're definitely something where, there's a cost benefit and we don't want to be inundating ourselves with antibiotics 24/7, but we take them when necessary and they can be life changing like you said. Sort of in that vein, but not really because we don't really have anti-antibiotic rule. But this question is from Amy. She says, “I love the last episode where you both admitted you color your hair without shame [laughs] and not using cleaner options. I would be curious, what other things are you willing to "Bend the rules for?"”

Cynthia Thurlow: I'd probably say, like, if I go to a nice spa, there's an organic one in my area and I know what they use because we have conversations. But if someone takes me for a nice massage or I'm being treated to spa treatments, I do not micromanage what they're using on me because I will then not relax and enjoy myself. I'd probably say things that are leaning into pampering that are like gifts or they're just an experience. It's like I have to kind of readjust my expectations because if I start asking, then I'm going to be hyper focused on everything that's being used and that's actually not a lot of fun. I would probably say that is the other thing that I'm probably-- in that context, I'm probably very laid back versus what I purchase to use on my body at home. Very different. How about you? 

Melanie Avalon: That's so funny. When I go to massage or I get my nails done, I always bring my own stuff, [laughs] actually, and that's good for a question later. I used to think it would be cumbersome, but I mean, I have to be always doing my nails because of my Instagram and stuff like that. There's this one oil, I can put a link to it on Amazon. It's an MCT oil, basically, but it's a massage MCT oil, but it's just organic MCT. You can use it for everything. So, when I get a massage, I bring it with me and they don't care. When I get a manicure, it actually makes it cheaper because then I bring that and I don't have to get all the fancy upgrades and I give them that and I just let them use that for all of the lotion and everything and anything else massage oil wise. And then I got so excited because up until recently, I was having to have them use the scrubs that they have there, but over the holidays, Beautycounter came out with a limited edition scrub and a body polish.

Cynthia Thurlow: I have that. 

Melanie Avalon: Yeah, it's so good. So, for instance, if they still have that, because they tend to have it past the holidays stock up on it. I stocked up on it. So now I actually bring that-- It's one of the gift sets. Now I actually bring that with me to the nail salon as well. My other things that I bend the rules on, well, with wine at home I only drink, Dry Farm Wines. If I'm going out, I look up people know I do this, I look up every single wine and I find the organic ones and that's how I decide. I really want to make an app for this, by the way, so stay tuned. I should make that a goal for 2023 to get this app out there. If I am at a place and there's no organic wine, I will drink nonorganic wine. [laughs] 

I don't enjoy that, but I will. People know I do Emsculpt religiously. I love it. I am very concerned about the amount of radiation that it gives your body, but I think the benefits that I get from it as far as building muscle are amazing. I don't do it on my abs. People ask me that a lot, but I'm a little bit concerned about doing it right over my organs like that. So, I just do basically my extremities, my thighs, my bottom, my butt, my arms. And then this is a big one. This is a big confession. I'm probably going to be writing about this. I haven't done it yet, but I am contemplating doing Botox preventatively in my forehead. I wasn't going to, but I had a consultation and I don't know, I started really thinking about it, like, the preventative action of it and not having wrinkles down the line. So, I think what I'm going to do is because basically it's a trade-off of putting that because it is a neurotoxin. So, putting that into your body and the cost benefit, you just have to weigh the cost benefit, I think, of what matters to you or not. If I do do it, well, A, I'm going to do a ton of research. B, I really want to write a really epic blog post about this if I do it, because I think people will think if you do Botox that means that the rest of your skin care doesn't matter or that you don't value skincare. I think I want to kind of educate people on again. I need to do the research first, but if I proceed with this route, I want to maybe spread the word or awareness about the cost benefits of Botox and also why it's still super important to have really non-toxic clean skin care and why you might have both. So, we shall see.

Cynthia Thurlow: Yeah, and I think that's okay. I've always been very honest. In fact, when I was on Drew's podcast for the second time, we were talking in the context about Liver King. So, I'm sure most listeners know about Liver King and how he predominantly was focusing on this kind of paleolithic lifestyle and eating organ meats. God bless him, he eats organ meats, like, with reckless abandon. Like, it's fascinating. But as soon as I saw him, I remember saying to my son, who was like putting him up on a pedestal, I said you realize that guy is on a lot of steroids. 

Melanie Avalon: That's what everybody says. He denies it. Right? 

Cynthia Thurlow: Well, what came out recently was his steroids, like his anabolic steroid schedule and his stack of growth hormone and a bunch of other things. So, in that context-

Melanie Avalon: I missed that. 

Cynthia Thurlow: -yeah, I was saying it to Drew, I think it's important for people that are in the public eye that are influencers to be very, it's not like you have to disclose everything, but you should be honest. I think it's important for me as a middle-aged woman, in the context of our conversation, to say every year I do ProFractional, which is laser, stimulates collagen and elastin. I think that has a lot to do with why my skin looks really really good. I think some of its genetics and I think some of it's my lifestyle. And then I do Botox, I've done Botox since I was 38. I started doing Botox because I have always had a super mobile forehead and that's where it started. And I still do Botox a couple of times a year. I have done filler a few times. I've had it reversed as well.

I think a lot of if-- you chose to go that route and there's no judgment if you do. You want to work with someone that's incredibly talented. You should never look like you've had work. You should never look like your face is immobile. You should never look like your lips look, like this is just my personal opinion. You shouldn't look like you have massive lips and like crazy high cheekbones and just understanding. I think those products are designed to be used subtly, but I think if you see some people that are in Hollywood that are like the extremes, too much of any one thing is not a good thing. In the context of this conversation, I feel like I should be transparent and say that obviously a laser is pretty benign in terms of stimulating collagen and elastin. I don't per se have a problem with using Botox or fillers very discriminately because so much of the rest of my life is so incredibly healthy and balanced.

And to the person in my DMs recently who was giving me a hard time about the fact that I shared those things. Yeah, this is why people that are in, whether they're influencers, they're in the public eye, this is why people honestly don't want to share because they don't want to be criticized. But I don't care if anyone agrees or disagrees with that decision because to me it's my decision. With that being said, I think I would be doing the listeners a disservice if I didn't share that as well. 

Melanie Avalon: Well, thank you for sharing that and I am so enjoying this conversation. I have some quick thoughts and questions. One, mentioning the laser, is that the same thing as BBL? 

Cynthia Thurlow: So, I'm going to say BroadBand Light is different than the Brazilian butt lift because I very innocently last year said, “Oh, I got BBL.” And people were like, “You did?” 

Melanie Avalon: Yeah, you said that to me. I remember you were like, you said you were getting BBL. So, something about the next day and I was like, “Oh goodness, that's like an intense surgery,” because I think we still recorded a podcast maybe the next day. I was like, “How is she doing this right now.” 

Cynthia Thurlow: Yeah, this tells you how long I've been doing BBL. It was preceded the Brazilian butt lift, which I'm told is going out of favor according to my plastic surgeon friends, which is a whole separate tangential rabbit hole that we won't jump down. In conjunction with ProFractional, I do BBL and what it's doing is any brown pigmentation. I don't have a lot of hyperpigmentation in my skin. We do that preceding the ProFractional. I hate it. I hate both of them honestly. It's like a love-hate. I'm doing it in January, which is usually the month I do it. I hide for four days and then I feel fine. With that being said, the laser in and of itself is looking for the pigmentation helps dissolve it. If you have some brown pigmentation, the laser will identify it, it will help dissipate it, but it will actually get darker for a couple of days or maybe a week and then it goes away. 

For me, I think the two of those together have been super powerful. But, for anyone that's just doing BBL - BroadBand Light, it is not painless. Make sure whoever you're working with is like getting you prepared for that because it's almost like having a rubber band snapped against your skin. As you can well imagine, doing it once is not a big deal. If they're doing your whole face that can be painful. Just make sure that they're giving you either topical lidocaine or giving you something to make you feel comfortable. 

Melanie Avalon: Although caveat, also check and make sure your practitioner lets you use that because it was during the podcast last time when we were talking about I was going to go do it and then I put on numbing cream during the podcast, which apparently is some people let you. But, where I went to Ideal Image, which I'll say their name because I think they're the biggest. They're like the go-to place. They do not let you use numbing cream. So, do not use numbing cream if you're going to them.

Cynthia Thurlow: Yeah, and my practitioner, they put it on for you. Like when you arrive, you arrive an hour before your treatment and they put it on for you. With very few exceptions, I'm very comfortable with BBL. There are spots when they do ProFractional that are tender, like along your forehead line. It freaks me out when they do underneath my eyes and my nose is a little sensitive, but beyond that, not bad. Not bad at all. 

Melanie Avalon: I've heard that old therapy is the most painful thing.

Cynthia Thurlow: Morpheus is supposed to be very, very painful. I'm not ready, if someone were to give and actually the person I go to who trains providers all over the United States doesn't use those technologies yet, because she still feels like ProFractional has just as much benefits. But every time I see her, I'm like, “So what's the latest?” And then she'll kind of get me caught up.

Melanie Avalon: What's really interesting though, because you mentioned the laser, so I was talking with a friend about whether or not I should do Botox or not. It's funny because he mentioned people doing lasers and Botox and whether or not you talk about it on social media, it's interesting that for some reason, Botox, I think, has more of a stigma. I have literally no issue talking about BBL or lasers or that seems almost like biohacking in a way, but for some reason, Botox feels more fake. I don't know why because I was thinking about it more, it's not even affecting your skin, it's just paralyzing the muscle underneath so you're not wrinkling your forehead all the time and not forming those lines that last. So, I find that really interesting. I mean, I think you could make the argument that well, maybe not it's because you can make the argument that Botox is biohacking [laughs] but--

Cynthia Thurlow: I think you could and here's the thing, like, I just interviewed Dr. Amy Killen, who's a female biohacker physician, and she's so knowledgeable and offline we were having discussion about some of the things that she does. She's very transparent and that's why I hope to be just as much for listeners so they can kind of get a true sense, like some of this is genetic, some of its lifestyle, and then I get help from other things. That's what we're sharing in the context of this conversation. Amy was talking about, she does all the things, PRP, stem cell stuff. It's very interesting. There's a continuum. It's all very relative. To some people, Botox may be like taboo and then others are like, "I'll do everything up to surgery." Some people are like, "I want to do everything up to surgery and surgery," and there's no judgment provided that you can afford it and you're not body dysmorphic. I think that everyone has to decide what they're comfortable with and what makes sense. From my perspective, I just wanted to add that caveat that I think I want to be fully transparent as a 51-year-old female that I try to do as many things as I can to feel as good as I look internally and reflect that externally as well.

Melanie Avalon: Yeah, I could not agree more. And then when I was talking to that friend, I said, I was like, “Well, it's a neurotoxin.” He was like, “Well, wine is a neurotoxin.” I was like good point [laughs] or alcohol. Yeah, no, I agree with the perspective and what's important to you and no judgment and just do you.

Cynthia Thurlow: I think it's just a healthier space to exist, and I don't have the emotional bandwidth to sit around and be judgy of other people's choices. It's like as long as you're not hurting anyone, there's very few absolutes where I'm okay, that's not a good decision. If you're harming yourself, a child, an animal, other humans, that's not good. Beyond that, it's like, I just don't have the bandwidth to worry about what everyone else is doing. It's like, if it works for you, that's great. If it doesn't, then course correct. 

Melanie Avalon: Also, one last thing to that point and I mentioned this earlier, but it's like, oh, if you're getting Botox, people might think you're lying about the importance of safe skin care or antiaging skin care. But, if you think about it, they're all really important. Like doing a process where you're paralyzing the muscle and keeping wrinkles from forming from just the mechanics of your skin doesn't negate the super overwhelming importance of taking care of your skin. Like, you would still need to do both.

Cynthia Thurlow: I take AG1 several times a week after working out and when I’m ready to break my fast and it really makes me feel unstoppable. I love to add it to a protein smoothie or actually will drink it with filtered water and I love both variations. My 17-year-old also enjoys AG1 after a workout to ensure he stays really well hydrated. A great deal of what I focus on in my personal life is ongoing gut health improvement. I do feel fundamentally that AG1 has contributed significantly to improvements in my gut health over the last three years. I feel as if the key health benefits from multivitamins, minerals, pre and postbiotics all work together synergistically to improve my gut microbiome. AG1 is way more than just greens. It’s important to note that it’s made with 75 super high-quality vitamins, minerals, and whole food source ingredients that deliver incredible benefits to the gut microbiome, as well as sleep support, assistance with energy, and so much more.

So, if you want to take full ownership of your health, today is a good time to start. Athletic Greens is giving you a free one-year supply of vitamin D and five free travel packs with your first purchase. I find that these five free travel packs are so convenient when you’re traveling. In fact, I was in Los Angeles last week and I used one each day that I was away. Go to athleticgreens.com/ifpodcast that’s athleticgreens.com/ifpodcast and check it out.

Melanie Avalon: Damon wanted to know, laser hair removal, is it worth it?

Cynthia Thurlow: Oh my God, yes. Oh my God, yes. It's funny. You do laser therapy and then you realize in your 40s into your early 50s, you don't have as much body hair. So, I'm like, what was I thinking. I went gangbusters in my 30s. Yes, yes, yes.

Melanie Avalon: I agree. I don't think I commented on barely any of the comments in the thread. But when I saw this one, all I did was I wrote yes, all caps.

Cynthia Thurlow: Yeah, well, think about it. People spend years doing bikini waxes and electrolysis.

Melanie Avalon: And think about forgetting to shave your underarms or your legs. You don't have to anymore.

Cynthia Thurlow: Yeah, although it's funny, I did my legs and my bikini area and I guess I took too well to it because I bought a package. They were like, literally “You've done so well. What else can we do? What else can we do for you?” For me, it was like life changing because I had done like, bikini waxes every month forever and eternity, and then all of a sudden I was like, this is great. 

Melanie Avalon: It's funny because when they try to sell you stuff and they're like, “This will be the best thing ever,” and you're like, “But really?” No, it really is. [laughs] 

Cynthia Thurlow: No, it's resounding. It is worth every penny, every single penny. 

Melanie Avalon: Yeah. I've done the Brazilian, the arms, the legs. Now I'm doing the upper lip. I think that's everything. [laughs] There's nothing left.

Cynthia Thurlow: I had blonde hair on my face. I've been just doing dermaplaning because to me and it's like, here's a fun topic for conversation. During the pandemic, when I could not get to get threaded or dermaplaning or anything, my anesthetician had recommended something called Tinkle, T-I-N-K-L-E. You can find it on Amazon. It's like really inexpensive and it's a little like razor for women, so you can get rid of fuzz on your face. Oh my God life changing. I literally was like, what was I spending all this money on threading for, for years [laughs] and then waxing before that. I was like, “Oh my God.” 

Melanie Avalon: Is it special or is it just a little razor? 

Cynthia Thurlow: Yeah, so it's for your face and it's not as strong as what a man would use. To me, it's like I can use it in between facials. And it's amazing, just amazing. For all those little weird hairs, if you like mind just tweeze them. I'm like, “Oh my God, this is amazing.” So highly recommend.

Melanie Avalon: They always have these at Marshalls and TJ Maxx. Maybe not that brand, but I use those or I used to. Oh no, I still do because I'm still doing the upper lip. Okay, here's back to non-skincare health, beauty-related things. What are your top three book recommendations besides your own?

Cynthia Thurlow: Okay, I've given this a lot of thought, I would say the books that are really in terms of health and wellness, I'm going to just leave it there because there're so many books. I would say the books that really shifted my perspective on a lot of different things, XX Brain by Dr. Lisa Mosconi, who I've been trying to interview for a year. She's like knee deep in research. She works at Cornell. That book helped me solidify why women-- and this is my opinion why women can benefit from hormone replacement therapy.

I would say the other book that I found really helpful, like in that space is Why Estrogen Matters by Dr. Avrum Bluming and Carol Tavris. I have had him on the podcast. We will link that in the show notes. The Women's Health Initiative is probably the most detrimental study that's ever been conducted on women in terms of the net impact on practitioners prescribing hormones and women taking hormones. You have a whole generation of clinicians and women who are fearful to take and/or prescribe medications. 

I would say, most recently, a book that really has had what I would say is this book, is the book I can read now because I've done the work. The Myth of Normal by Dr. Gabor Mate and that podcast will be out with him on December 24th. So, talking about the role of trauma in your life, I mean, he's changing the narrative for the way that we view trauma and doing it in a way that is through the lens of compassion and as someone that's a survivor of childhood trauma, both physical and emotional. For me, that book just allowed me to view my parents from a very compassionate lens. I would say those books right now in terms of health and wellness are the books that I probably recommend the most. For full disclosure, they're not easy-breezy reads. Lisa Mosconi's book, I think, is one that I recommend quite a bit to patients and clients that is more accessible. Myth of Normal is excellent, it's long and I would say that Why Estrogen Matters is a good read as well. How about you? 

Melanie Avalon: That's really awesome recommendations. So, I think my favorite is Lifespan. Oh, wait. No, I'm torn. Well, okay. So, Lifespan, David Sinclair's book, Why We Age and Why We Don't Have To. It's basically just everything I'm obsessed with. And what I love, when I interviewed him on the show, I might have told you this. Did you know he drew all of the characters in the back? 

Cynthia Thurlow: Really? So talented. 

Melanie Avalon: Yeah. He said that because in the very back there's hand drawn pictures of the people and everything. He drew all of those. He said he drew them because he wanted to put the actual pictures or whatever, but they couldn't get the rights to everything. So, he's like, “I'll just draw it.” [laughs] Isn't that crazy? 

Cynthia Thurlow: Well, that's along the lines of, like, when I'm in awe of people that are doing something artistic on a stage in the performing arts, okay, there's another level to my respect for him. 

Melanie Avalon: Yeah, no, it's insane. And if so you listen to my, that was the first interview I had with him. If you listen to it, he tells me this in real time, and I'm just, like, in shock, in shock. I'll probably say, this is so hard. You know what I haven't read The Paleo Solution since I read it in, like, 2012. But that's what changed my life. Like, that's the reason I'm doing what I'm doing today. Robb Wolf's book, I think I will have to include that I'm torn between James Nestor's Breath and I think I might have to do Kelly McGonigal's The Upside of Stress just because that book-- I need to try to get her on the show. That book was so valuable for me because I started stressing so much about stress, which, yes, stress has a lot of negative health effects. That's no surprise. It's not really negotiable. There's this whole aspect to it where perception affects how stress affects you. And so, reading that book took the biggest weight off of my shoulders about stress and how you can reframe your experience of stress and use it to your benefit rather than as a detriment. 

Cynthia Thurlow: I love that. It's someone said to me years ago, trying to pick your favorite book is like trying to pick your favorite child, it's impossible. Where I sit, where my desk is in my study, I literally have the ability to see hundreds of books. It's so hard because there're so many great books that I've read, but it's impossible to have a favorite. Just for listeners to understand, those are the three that have had the most impact on me. They've just completely blown my mind. Obviously, the ones that Melanie is identifying, two out of three I've already read. But I'm always reading. Just like, Melanie, I've actually got Sally Norton's new book on my floor to read, I'm like after I get done with podcast prep for this week. 

Melanie Avalon: I feel so bad because I always get her confused with Susan Owens because they both talk about oxalates a lot. I've had her on the show.

Cynthia Thurlow: Yeah, this will be my first time. I've had one other oxalate expert who I think is trained with her, but her book is coming out. So, I was like, it's probably time to revisit the oxalate issue. 

Melanie Avalon: That's awesome. I didn't realize she had a new book coming out. 

Cynthia Thurlow: Yeah, it's called Toxic Superfoods. [laughs] I'm sure there will be lots of overlap with Gundry's kind of methodologies about plant-based toxins.

Melanie Avalon: That's awesome. Awesome. Here's a quick one. This is from Danielle, "What is your favorite holiday tradition?"

Cynthia Thurlow: I think a lot of the traditions that are important for us is just a lot of togetherness, a lot of disconnection from work and social media and things like that. I would say there're a lot of things that we have done as a family including like decorating the tree, decorating the house, making cookies. When my kids were younger, they were more interested, invested in those things. But I think it's the quietness around, like Christmas Eve when we go to Mass and then we read particular Christmas books and then there's a nice meal and just savoring that time. There was a recent study that came out and it talked about how much time you spend with different people throughout your lifetime. As someone with a 17-year-old and 15-year-old, I read this study and my heart hurt. The great thing that I'm going to bring to this conversation is that it just reaffirms why it's so important to connect with one another. 

So, when I think about holidays, I just see it as connection, like spending time together, making meals together, making memories together, not per se, like one specific thing, like do we drive around and look at Christmas lights? Yes. Do we make specific kinds of meals? Yes. But what I value the most, especially now that my kids are older, is just being together, being silly, watching movies, trying to deal with all of the challenges of navigating in laws and parents and expectations for kids and everything else. How about you? Does your family have special traditions around Christmas or the holidays? 

Melanie Avalon: Well, first of all, I'm obsessed with everything Christmas, and mine was basically the same on Christmas Eve, we'd always had a tradition growing up of opening like, one present the night before and trying to make it a present that is something we could do together. Normally it's like if somebody gave somebody a game or something, and then we would do the gift and yeah, that's always been my favorite thing hands down. We are a big wine loving family. Having the Christmas wine and opening the presents and the Christmas Eve and playing the music, Trans-Siberian Orchestra, I am all about it. I love it. Actually, what we've started doing, I feel like it's been ever since everybody's been adults, it's been changing around. Now sometimes I think last year, maybe even the year before, we opened all of our presents just on Christmas Eve, the night before, because people are more, I don't know, spirited and lively in the evening than coming all over during the day.

Cynthia Thurlow: We've tried that. My kids always beg. My husband's kind of a traditionalist about the gift stuff. I think because I grew up with divorced parents, we just opened gifts. When we opened gifts, it wasn't regimented. My kids every year are like, can't we just open gifts on Christmas Eve. And my husband gets very rigid. I just always say, my husband's 90% of the time he's really easy going, and if he gets fixated one thing, I just tell the kids, back off. So, yeah, they're allowed to open one gift on Christmas Eve and then the rest on Christmas. 

Melanie Avalon: Yeah. We didn't start doing this until very recently, and we're all very much adults now, but growing up like your kids' age, we never did more than one the night before. I don't think we even wanted to. My dad is that way with Monopoly, because Monopoly is always the game we would always play, and we'd always want to do things like play how there's, like, 50 million spin offs of Monopoly, like, all the different themes? No, he, like, only wants to play the original. We would always have debates about, like, the rules and because there's a lot of, I think, like, little fun things you can add or change the rules little bit, nope. [laughs] It had to be the traditional way in the rule book. 

Cynthia Thurlow: I'm married to an engineer, so I'll just leave that there. Anyone that's married to engineers, know engineers, you understand they can be a little rigid sometimes, but I give him a lot of credit because he's usually pretty laid back about a lot of other things. 

Melanie Avalon: So funny. Two last quick ones. So, one is sort of health related. Leslie says, “I work at HOTWORX, 24 hours Infrared Fitness Studio. What do you think about a 3D workout heat exercise infrared sauna?” 

Cynthia Thurlow: Okay, I know exactly what HOTWORX is and I love the idea. I'm going to come at this from two lenses. So, number one, I hate being hot, really hot when I'm exercising. Hate it. Like warm yoga, good. Ashtanga yoga, that's at 105 degrees. No, don't enjoy it at all. For me personally that would be a no, because I just don't enjoy being really hot unless it's hot because I'm exercising at a level that I'm increasing my basal metabolic rate and my internal thermostat.

Number two, I think the concept of a 3D workout sounds great. I think it's probably highly bio individual. If you are a 25-year-old woman who is really lean and you're pushing yourself all the time, and you're not getting a menstrual cycle and you're overdoing it, I kind of call it the triad of over fasting, over exercising, over restricting. 

But I think for probably the average person, it's probably, like, a fun way to exercise. We have to think about what heat and exercise are. They're forms of hormesis. It's the right amount of stress at the right time. I think that it's important to recognize where are you in your cycle, how is your sleep, what's your stress like. Like, it's just adding additional stressors to your body. I think in the context of someone who's sleeping well, who's in the follicular phase of their menstrual cycle, who doesn't have too much stress, that's not overdoing it and is staying hydrated, it's probably fun. That would be my guess. 

Melanie Avalon: That was basically my answer, was that I think it could be really great like, it can be a great way of hacking and getting more bang for your buck as far as benefits go. But you also need to know yourself. I'm literally just spitting out what you just said. You have to know yourself and some people it's going to be too much and it's going to be overdoing it and it's not going to have the beneficial effects in the long term because it's not allowing the adequate recovery in between. And if it's fitting into an overly stressful lifestyle anyway, it might not be the way to go. I think you really just have to know yourself. I haven't done HOTWORKX. 

Cynthia Thurlow: Yeah. no offense to anyone who loves working out in a super hot environment. I hate it. I've been that way my whole life. Hate it with a capital H. For me, like if I went to the gym and it was cold in the gym, good. If I walk outside and it's kind of hot and humid, not as interested in walking as long. But it's not that I don't see the utility I just personally hate being that hot. I hate it, just despise it. The only thing I can compare it to is like, being in Morocco, which was like an oven. [laughs] We're telling my husband I don't think we'll ever come back because it was just so hot. 

Melanie Avalon: I'm the same besides my sauna sessions where the purpose is being hot and it's relaxing, especially with infrared, not getting that hot. But I'm not about the heat. I'm all about the cold. are you guys getting a crazy cold front because it's getting down next week to 10 degrees. It doesn't get 10 degrees here. 

Cynthia Thurlow: Yeah. Atlanta is going to be in a kerfuffle. Yeah. For me, it's like when I walked my dogs this morning, it was 30 degrees and it's like perfect for them. I put a hat on, I've got a light jacket on and I'm totally happy. 

Melanie Avalon: I'm so pumped. Especially because the last few years has been warm on Christmas, it's going to be like 15 degrees. I am all about it. This is going to be great. 

Cynthia Thurlow: Yeah. I just feel like Christmas should be cold. We had, gosh it was probably ten years ago, we got snow in Virginia on Christmas Eve and it was like a dusting, but that's still like in Northern Virginia that's a shutdown mode. Everyone's freaking out. I was like, this is completely appropriate.

Melanie Avalon: I'm just worried about ever since that Texas, was it Austin or wherever when it got really cold and didn't it mess up all of the water, like the pipes and everything. I'm like, please, that cannot happen. [laughs] I need my toilet.

Cynthia Thurlow: Well, you know what they always say. I lived in a neighborhood in Northern Virginia and most of the homes were new construction when people bought them and the builder knucklehead that they were a lot of exterior pipes were freezing during really cold spells. If you're ever concerned about your water freezing in a pipe. You can always keep your water like a little drip just to kind of keep things moving. Yeah, lots of experience with friends who went through that. Not fun. Not fun at all. 

Melanie Avalon: Yeah, they always post-- when it starts getting cold they post signs everywhere saying, “Freeze warning and let your faucets drip.” Okay, well, this was fun. This is definitely going to be a two-parter. I'm thinking it's probably going to be a three-parter, maybe a four-parter. 

In any case, for listeners, if they would like to submit their own questions for the show and if this is your first episode listening, which since we get so many listeners, it probably is somebody's first episode listening, welcome to that person. Normally we talk about Intermittent Fasting a little bit more. You can submit your own questions to questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. These show notes will be @ifpodcast.com/episode300. Those show notes will have a full transcript as well as links to everything that we talked about. So, definitely check that out and you can follow us on Instagram. We are @ifpodcast. I am @melanieavalon. Cynthia is @cynthia_thurlow_. I think that is all the things. Well, this is been really, really fun, Cynthia. Anything from you, before we go?

Cynthia Thurlow: No, I'm looking forward to round number two.

Melanie Avalon: All right, sounds good. I will talk to you next week. 

Cynthia Thurlow: Sounds good. 

Melanie Avalon: Bye. 

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing a review on iTunes. We couldn't do this without our amazing team, administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and re-composed by Steve Saunders. See you next week. 

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Dec 25

Episode 297: Ashwagandha, Diabetes, Berberine, Creatine, Long Term Calorie Restriction, Women In Podcasting, Echo Chambers, The Four Tendencies, And More!

Intermittent Fasting

Welcome to Episode 297 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

BUTCHERBOX: Grass-Fed Beef, Organic Chicken, Heritage Pork, Wild-Caught Seafood: Nutrient-Rich, Raised Sustainably The Way Nature Intended, And Shipped Straight To Your Door! For A Limited Time Go To Butcherbox.com/ifpodcast And Get The New Year bundle for free plus $10 off when you sign up today. That’s a 14 oz pork tenderloin, 2
lbs of ground turkey, and 4 top sirloin steaks free in your first box!

ATHLETIC GREENS: 75 High-Quality Vitamins, Minerals, Whole-Food Sourced Ingredients, Probiotics, And Adaptogens In One Delicious Scoop! Get A FREE 1 Year Supply Of Immune-Supporting Vitamin D AND 5 FREE Travel Packs With Your First Purchase At athleticgreens.com/ifpodcast.

Bon Charge: Overexposure To Blue Light In Our Modern Environments Can Lead To Increased Anxiety, Stress, Headaches, Insomnia, And Other Health Conditions. Unlike Many “Blue Light Blocking” Glasses On The Market, Bon Charge Provides Glasses That Block The Exact Blue Wavelengths You Need To Regulate Sleep, Reduce Anxiety, And Much More! They Also Provide Different Types Of Glasses For The Time Of Day, Season, And Your Personal Electronic And Light Exposure! Go To boncharge.com And Use Coupon Code IFPODCAST To Save 25% through January 2nd!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX:  For A Limited Time Go To butcherbox.com/ifpodcast And Get The New Year Bundle For Free Plus $10 Off When You Sign Up Today. That’s A 14 Oz Pork Tenderloin, 2 Lbs Of Ground Turkey, And 4 Top Sirloin Steaks Free In Your First Box!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

The Melanie Avalon Biohacking Podcast Episode #177 - A.J. Jacobs

The Melanie Avalon Biohacking Podcast Episode #175 - Seth Stephens-Davidowitz

ATHLETIC GREENS: Get A FREE 1 Year Supply Of Immune-Supporting Vitamin D AND 5 FREE Travel Packs With Your First Purchase At athleticgreens.com/ifpodcast.

Listener Q&A: Cici - ashwagandha & diabetes

AVALONX BERBERINE: Stock Up During The Launch Special From 12/16/22-12/31/22, Get 15% Off Of 1 Bottle With Code MABERB15, And 25% Off 2 Or More Bottles With The Code MABERB25! Site Wide Get 10% Off avalonx.us And mdlogichealth.com With The Code MelanieAvalon!

Listener Q&A: Niki - Creatine

BON CHARGE: For a limited time Go To boncharge.com And Use Coupon Code IFPODCAST To Save 25% through January 2nd!

Listener Q&A: Alex - Hi Ladies!

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 297 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: A 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine if it's that time, and get ready for The Intermittent Fasting Podcast.

Hi friends. I'm about to tell you how you can get a 14-ounce heritage-breed pork tenderloin 2 pounds of sustainably raised ground turkey and four grass-fed top sirloin steaks all for free plus $10 off. Yes, all of that incredible meat plus $10 off all for free. We are a bit obsessed with the company called ButcherBox, which is always in season. Some of my favorite meals that I had throughout the holiday season were fantastic meat and seafood from ButcherBox. Now, with the new year, it is time to celebrate with only the very best of the best when it comes to meat and seafood that you put in your body as well as meat and seafood that helps support our planet and the environment. 

They make it so so easy to get high-quality, humanely raised meat that you can trust. They deliver 100% grass-fed, grass-finished beef, free-range organic chicken, heritage-breed pork that's really hard to find, by the way, and wild-caught sustainable and responsible seafood shipped directly to your door. When you become a member, you're joining a community focused on doing what's better for everyone. That includes caring about the lives of animals, the livelihoods of farmers, treating our planet with respect and enjoying deliciously better meals together. I did so much research on ButcherBox. You can actually check out my blog post all about it at melanieavalon.com/butcherbox. All of their beef is 100% grass-fed and grass-finished, they work personally with all the farmers to truly support the regenerative agriculture system. I also did an interview with Robb Wolf on my show, The Melanie Avalon Biohacking Podcast, all about the massive importance of supporting regenerative agriculture for the sustainability of not only ourselves but the planet. This is so important to me. I'll put a link to that in the show notes.

The value is incredible. The average cost is actually less than $6 per meal. And it's so easy. Everything ships directly to your door and it is so delicious. I love carpaccio for example, the ButcherBox steaks are incredible for that. That's how you know it's good steak when you can eat it rare like that. ButcherBox has an incredible offer for our audience. You can get the New Year bundle for free plus $10 off when you sign up today. That's a 14-ounce heritage-breed pork tenderloin, 2 pounds of sustainably raised ground turkey, and four grass-fed top sirloin steaks, all for free in your first box. Sign up at butcherbox.com/if podcast and use code IFPODCAST to claim this offer. Again, to get a 14-ounce heritage-breed pork tenderloin, 2 pounds of sustainably raised ground turkey, and four grass-fed top sirloin steaks all for free plus $10 off. Sign up at butcherbox.com/ifpodcast and use code IFPODCAST to claim this offer. We'll put all this information in the show notes.

And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting, it's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things, like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup may be playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That's because ladies when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years.

Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means when you put on some conventional lipstick, 30 years later maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life. And their makeup is amazing. Check out my Instagram to see what it looks like. Tina Fey, even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook Group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well.

And lastly, if you're thinking of making Clean Beauty and Safe Skincare a part of your future we have, we definitely recommend becoming a Band of Beauty member. It's sort of Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now back to the show.

Hi, everybody, and welcome. This is episode number 297 of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hey, Melanie. How are you? 

Melanie Avalon: I'm good. I have a question for you. Have you done, is it, BBL, for laser? 

Cynthia Thurlow: Broadband light?

Melanie Avalon: Yeah.

Cynthia Thurlow: Yes. I do that in conjunction with Profractional once a year.

Melanie Avalon: I'm about to do it right after this.

Cynthia Thurlow: Well, did they tell you that it's not painless? I don't share that with you to frighten you. No one told me that. The first time I had just plain BBL, it's like snapping a rubber band against your skin.

Melanie Avalon: Oh, awesome.

Cynthia Thurlow: I'm sure they'll probably give you something topical, but if they don't ask for It.

Melanie Avalon: Oh, should I put numbing cream on my face? I have it.

Cynthia Thurlow: I would bring it with you and just double-checked. They may have something that they want you to use.

Melanie Avalon: Is it okay if you have cream on your face?

Cynthia Thurlow: They're probably going to clean it. I would ask them what their protocol is?

Melanie Avalon: Probably should have thought about this a little bit earlier.

Cynthia Thurlow: Because, I can tell you BBL is not painless, but with numbing cream it is tolerable.

Melanie Avalon: Okay. I might put on some numbing cream while we're talking, so it can be like soaking in because I think it has to soak in for a little bit because I do laser hair removal and always use the numbing cream for all of that.

Cynthia Thurlow: Did they give you lidocaine in a jar? 

Melanie Avalon: Yeah, I have that and then I have, there's one I order on Amazon that I like as well.

Cynthia Thurlow: Okay. It's probably not as strong like when I get Profractional and BBL done on my face, it's like the most you can legally prescribe. It works very effectively. Like my face will stay numb for 2 hours.

Melanie Avalon: Wow. Okay, I might grab some. Second question is because I'm glad you've had it, they said I'll be fine because I am recording with Ben Azadi tomorrow.

Cynthia Thurlow: Oh, you'll be fine. Yeah. If you have melasma or if you have any brown discoloration on your face, it'll make it darker, but it's not like you can't function. It'll be darker and then it all flakes off and go away.

Melanie Avalon: Yeah, that's what people said. They said it rises to the surface and then falls off.

Cynthia Thurlow: Yeah. It's like if you have an exaggerated freckle and then it goes away.

Melanie Avalon: And then it goes away. I'm very excited.

Cynthia Thurlow: Yeah, it works very effectively and I think most people don't even realize how much brown pigment they have in their face until they get it done and then they're like, Holy cow.

Melanie Avalon: It's pulling out the pigment from your face, sort of?

Cynthia Thurlow: The laser itself helps to break up the pigmentation. Like you can have red areas in your face and you can have discoloration like brown areas. Especially for women that have been on oral contraceptives or just have had a lot of sun exposure, they can have melasma and pigmentation on their face that most women don't want to have, so it's an easy way to help address it.

Melanie Avalon: Awesome. I've heard really wonderful things about it.

Cynthia Thurlow: Yeah. I go once a year and I always say, like, I have a love-hate relationship. I love the way it looks once I've healed, but I don't love it at the time. It's quick, so it'll be over before you know it.

Melanie Avalon: Well, I'll start while we're talking, I'll be rubbing some numbing cream on my face. What's new with you?

Cynthia Thurlow: Not a whole lot. Gearing up for the holidays and excited to not be traveling. Last Christmas we went away, we had a wonderful vacation and my kids kept saying, it's just weird for it to be warm [laughs] in Christmas. This year they wanted to stay home and so we are staying home and my mom and stepfather are coming to visit. Be a little bit of high [unintelligible [00:11:15] my mom is here but she means well. You know moms can be.

Melanie Avalon: Yeah. Holiday, family dynamics.

Cynthia Thurlow: Yes. How about you?

Melanie Avalon: Well, actually to that, my dad actually is having surgery, and it's a pretty intense surgery, so I'm sure it's going to be fine. It's really made me want to make sure I do a lot of stuff. I mean, it's going to be fine. We planned a lot of really fun things to do. Like, this weekend I'm going over we're going to just have a game night, and then we're going to do an escape room that's King Tut themed. Have you done escape rooms?

Cynthia Thurlow: I have not yet. I think when that started to become really popular, it was like preceding the pandemic and then the pandemic happened and we never did it.

Melanie Avalon: They're so fun and when you do them, you just realize, I feel like they're really good for your brain, your body because you're like moving all around. They're very immersive. Yeah, they're super fun. I've only done two. This will be my third one, but I would love to do them more. Actually it's funny, I interviewed A.J. Jacobs. Do you know him?

Cynthia Thurlow: I do not.

Melanie Avalon: He's so funny. It's been one of my favorite interviews to date. I was dying laughing. He wrote a lot of books. He's like a four times New York Times bestseller. He just does random stuff. Like his most well-known book. He just read the entire encyclopedia and talks about what he learned from it. The puzzle book, though, was about puzzles. In any case, he just has a section on escape rooms and this never occurred to me. Apparently, there're a lot of cliche guests that show up at escape rooms and one of the cliches will be the guy that will ask a girl on a first date and take her to the escape room, but he's done it multiple times, so he knows all the answers, and then he acts like he doesn't.

Cynthia Thurlow: Okay.

Melanie Avalon: Sneaky.

Cynthia Thurlow: Yes.

Melanie Avalon: All the escape rooms, but anything else new in your life?

Cynthia Thurlow: No, just gearing up for 2023 and trying to survive day to day with teenagers that are at times snarky and at times funny and trying to remind myself that those pleasant little cute kiddos are buried deep within them. I have moments where I'm just like, "Oh, my goodness." We just got back from visiting three colleges last week, and one with a big stand out for my son, who I think wants to study engineering. And it's hard to believe. It's like I blink. I remember when he was born and it's like, how is it possible that we're looking at colleges? This is like a top 20 engineering program, and so it's like one out of eight kids get in. It's really intense. Having to explain to him, you got to work your butt off. This is not half-assing anything. And he's got, like, four AP classes. He's got a pretty intense year, so we're just trying to help him head in the right direction, and hopefully, he'll have a couple of reaches and a couple of safety schools and then have some others that are pretty much guaranteed. But we're fortunate we're in a state where there are a lot of, I would say there's probably three or four really good state schools that a lot of people come to from out of state, so we're fortunate. Do you remember those applying to college years?

Melanie Avalon: I graduated early, so I applied when I was a sophomore in high school, so I didn't even go through the college application process.

Cynthia Thurlow: Oh, my gosh.

Melanie Avalon: Yeah, I applied to USC. They have an early entrance program. I found out, I guess early junior year and then I left after that year.

Cynthia Thurlow: That's interesting because they have two early decision options now. This is how it is in each school we looked at and one is binding and one is not. Essentially, they take the university he wants to go to. That's his first choice. They take 350 students, early decision.

Melanie Avalon: So, it that where you skip senior year of high school?

Cynthia Thurlow: No, he's going to need to go his senior year.

Melanie Avalon: Oh, it's just like making the decision earlier.

Cynthia Thurlow: Yeah. Well, he would be if he does an early decision and gets accepted, he knows November 1 where he's going to go the following year, but that's binding.

Melanie Avalon: Okay. Yeah. I got to live vicariously through my other friends and then also, like, my siblings. And it was fun. They actually let me in my high school, they let me go on the senior trip even though I was gone. I had been in college a year and then I went on my senior trip with my high school friends and they were just graduating.

Cynthia Thurlow: What was that like to go to college? I'm guessing you were a year younger than you would have been, but obviously very dedicated.

Melanie Avalon: Yeah. I was 17 and it was funny. I don't know if he wasn't in my program. The program that I did, they had 20 people that they take every year for that program. Not in my program, but I met somebody else who had done that and that person had actually skipped a year in high school as well. He was like 16 when he went, which is crazy.

Cynthia Thurlow: Oh, my gosh. Especially with a boy I can't even imagine. My son will be 18 in his senior year, and then he'll be 19 when he starts. With boys, they need a little more time to mature.

Melanie Avalon: Yes.

Cynthia Thurlow: And you get the gift of time. Like I always say, I will never regret sending my kids to school when they were 6 and not 5, so I got an extra year with them.

Melanie Avalon: Yeah, that makes sense. Besides the fact that I missed out on some senior-year stuff. I missed our basic econ class and government class, which I just feel like I missed out on some basics that I could have learned from that. I missed out on the literature class from senior year. Besides that, everything felt really normal. Like, it just felt like going to school.

Cynthia Thurlow: I mean, I think from my perspective, there are some people who are just way more emotionally mature and ready for the rigor. Like I say all the time, my youngest is at a [unintelligible [00:17:01] High School, and it's like college. I think college will be easy for him after this, and so he's just ready for it. I'm not so sure my 17-year-old is ready for that amount of rigor, but my 15-year-old is very, like, he sits down and literally comes home and rewrites his notes, tapes his notes, writes his notes, spends a week studying for an exam. I say all the time, like, we aren't doing this. He's doing this all on his own. He's very self-directed and so he's got a fire in his belly and that's innate to who he is as a human being, but I think it'll serve him well.

Like, he has talked about, he already knows where kids have been accepted for college from the high school he goes to. He's like, "Oh, they take this many to this university and this one to this one." Whereas, like, Jack, my oldest son, his high school will take three to the same university. Liam is like, "Oh, our school took 65." [laughs] It's an interesting dynamic, but they're exactly where they need to be. That's why I say, like, very self-directed, mature, focused kids. They might be ready earlier for those kinds of academic challenges and things like that.

Melanie Avalon: People are definitely all different. I'm just thinking back about how different me and my siblings are as well. You also can't really tell I don't know if I should be saying this publicly. My brother had his intense period where he was struggling, but he's, like, doing so well in life now, so people can really, I don't know, come out of anything.

Cynthia Thurlow: Yeah, now. I think anyone that's listening, whether they're reflecting on their own siblings or their kids, everyone kind of matures at a different pace. My oldest is a little more-- he's very smart, but he's a little more laid back. He literally for the first time in his life, has been really challenged in one of his AP classes. I'm seeing the effort he's making and he's doing that very self-directedly and I'm proud of him. You can't motivate him the way that I can motivate my younger one. It's very different. I have to be careful. Like, I'm the gunner. I'm the one that had the fire in the belly. To me, I understand my younger son and my husband understands my older son a whole lot better. We try to make sure we're conscious of that.

Melanie Avalon: I think I mentioned recently I interviewed Seth Davidowitz. His most recent book was Don't Trust Your Gut, but he has a whole chapter on parenting and the effects on children and their ultimate-- how they end up. I might have mentioned this on the show before. I just find it so fascinating. He really makes the case that it's mostly nature, not nurture with the exception of one factor. Did I tell you this? There's one parenting decision that parents can make that seems to really affect how their kids turn out. Otherwise, not so much.

Cynthia Thurlow: Interesting. What is that parenting decision? [laughs]

Melanie Avalon: It's where you live?

Cynthia Thurlow: Yeah, I can imagine.

Melanie Avalon: I guess because of the effects it has on their entire environment and how they grow up. It's where they live and how many adult role models they have that are not their parents.

Cynthia Thurlow: Yeah, it's interesting. To give you an example, so my youngest is a high school freshman and when he was in 7th grade in the midst of the pandemic, one of his teachers led a private class for him and a couple of his peers and they learned Macbeth. So, he knows Macbeth backward and forwards. So, sure enough, what are they reading in freshman year? MacBeth and his teacher said his grasp of concepts is so, first of all, it's unusual that he's interested. Number two, his grasp of the concepts and the nuances is so unusual. And Liam loves it. Like, he feels like a total empowered badass. He's kind of quiet in class, but his teacher said he always has this deep insightful comments. She said does he read Shakespeare on his own? And then I explained the context. Like, in the midst of the pandemic, we were trying to get him to interacting with some of his peers virtually.

This one teacher really took advantage of the fact that he could get them to be interested in Shakespeare. He still talks about this teacher how much of an impact he had on him and how grateful I am that during the pandemic, he was able to, A, be interested in learning about something and B, takes such a lead in his own education. He didn't turn it off. He just leaned in and learned and really enjoyed it.

Melanie Avalon: Yeah. No, that's amazing. Yeah, there's definitely that type of reading. All the things that's what I was doing growing up.

Cynthia Thurlow: Yeah. I could imagine you were like a little budding Liam, but the girl version, I get it, totally get it.

Cynthia Thurlow: Our next partner has a product I use literally every day. I started taking Ag One because I wanted to improve my gut health and have more energy. With one delicious scoop of Ag One you're absorbing 75 high quality vitamins, minerals, wholefoods-sourced ingredients, probiotics and adaptogens to help start your day right. This special blend of ingredients supports your gut health, your nervous system, your immune system, your energy, recovery, focus, and aging. It's lifestyle friendly whether you eat keto. Paleo, vegan, dairy free or gluten free, contains less than one gram of sugar, no GMOs, no nasty chemicals or artificial anything while still tasting good. Athletic Greens has over 7000 5-star reviews and is recommended by professional athletes. 

To make it easy, Athletic Greens is going to give you a free one-year supply of immune-supporting vitamin D and five free travel packs with your first purchase. All you have to do is visit athleticgreens.com/ifpodcast. Again, that is athleticgreens.com/ifpodcast to take ownership of your health and pick up the ultimate daily nutritional insurance.

Well, shall we jump into fasting-related things for today?

Cynthia Thurlow: Sure. Our first question is from CC, subject is "Ashwagandha and diabetes. I love your podcast. I would like to know if taking ashwagandha breaks your fast. I first read about it in the Prime Diet and started taking it before intermittent fasting, but I'm now afraid it will break my fast. My second question is on the link of intermittent fasting to diabetes. I'm so excited about fasting but just heard of the recent study that links fasting to pancreatic damage and type 2 diabetes. I have diabetes in my family history, but I'm very careful what I eat, more low carb, but this new study is scary. What are your thoughts? Thanks."

Melanie Avalon: All right, CC thank you so much for your question. Well, for the first one, for ashwagandha. Assuming it is just pure ashwagandha, it should not break your fast. I don't really do much with adaptogens, but you are a fan of adaptogens, right?

Cynthia Thurlow: I love adaptogens for many reasons and ashwagandha is one of these really flexible adaptogens, meaning it can be helpful for balancing cortisol. It can also be very calming, so you can take it sometimes in the morning and it can be energizing, and then you can take it in the evening and it can be balancing if you're feeling like your cortisol is high. It's also one of the best-researched adaptogens.

Melanie Avalon: I've taken ashwagandha a little bit. I personally didn't notice many benefits, but I know a lot of people have. Is it a nightshade? People say that.

Cynthia Thurlow: Yes, it is. If you're sensitive to nightshades, you want to avoid ashwagandha.

Melanie Avalon: Okay. The ones I have tried, I've responded well to Rhodiola.

Cynthia Thurlow: Yeah, Rhodiola is great at nighttime. I think my other favorite is probably Relora, so it's derived from magnolia bark and it's very calming, and that's a great one to take at night.

Melanie Avalon: Oh, interesting. The Rhodiola always made me energetic, so I would take it during the day.

Cynthia Thurlow: Well, it's interesting. Out of all the patients I've taken care of, I had one woman who swore it made her wide awake at night.

Melanie Avalon: The Rhodiola?

Cynthia Thurlow: Yeah. I think that has some bio-individuality, meaning, from that point on I stopped using it not necessarily with every patient, but I really started leaning into other options like Relora, which is really nice and very calming and nourishing for the brain.

Melanie Avalon: Awesome. Do you think you'll make some adaptogens in the future?

Cynthia Thurlow: I do, although I tend to be kind of a purist and so I definitely think about either a sleep blend or something that will be helpful in the morning to be energizing. I mean, I've vacillated back and forth, but I think most of my focus is going to be either on sleep support or things that are going to help with insulin sensitivity or muscle growth or muscle performance. I think initially those are going to be my focus, so I do think adaptogens will be part of that. It's just figuring out what's the right blend because when you start blending things together, you don't always know what's working and what isn't versus if it's just creatine or just one type of like magnesium L-threonate, which I love. You have a better sense, is this working for someone or not?

Melanie Avalon: Yeah, no, that's so true. I agree about the single things because otherwise you won't know. I guess speaking of things that really benefit blood sugar control, my berberine launched, when these airs it will have launched 10 days ago. So hopefully people stocked up. If you would like to get that, we are actually having a special. The special ends at the end of this month. Stock up now at avalonx.us, the special is you get 15% off of one bottle or 25% off of two or more. This is really the time to stock up. I've really been honestly floored because I was taking berberine originally just for blood sugar control, but after deciding to make it, I've really been researching all of the other benefits and it's overwhelming all of the benefits. GI health, obviously blood sugar control, reducing blood sugar, reducing cholesterol and lipids.

When it comes to the gut microbiome, it seems to increase beneficial bacteria and decrease more problematic bacteria. Actually, it helps the body's reaction to LPS, which is the toxic byproduct of bacteria. They think that actually might be a mechanism for how it affects blood sugar, which is interesting, which just speaks to how intensely our gut health relates to our overall metabolic health. I think our gut microbiome is affecting things way more than we realize.

Cynthia Thurlow: Oh yeah, I totally agree with you. It's interesting. I did IG Live, I'll be bringing Dr. [unintelligible [00:29:04] on the podcast in January, and she's a gastroenterologist, like a functionally focused gastroenterologist, and she has this great book that just came out talking about the role of viruses in the gut microbiome. It's really apparent to us that she and I trained over 20 years ago and Lord knows we knew very little to nothing about the gut microbiome. And it's almost like peeling an onion. The more you learn, the more humbled I am. That's actually going to be, it's called the antiviral gut, but she was fantastic and I cannot wait. I don't do many IG Lives anymore, but she was well worth the IG Live. That was definitely a highlight of my week.

Melanie Avalon: Yeah, that's amazing. We just don't even realize and I will comment though quickly, that the primary mechanism of action for berberine reducing blood sugar, I mean, I don't know, it's probably not the gut microbiome. It specifically affects pathways in the liver and can downregulate the liver's production of glucose and also can affect glucose absorption and utilization and insulin and things like that so yep. Again, the link for that is avalonx.us. Through the end of the year, you can get 15% off of one bottle and 25% off of two or more, and then after that you can use the coupon code MELANIEAVALON to get 10% off and that code will get you 10% off sitewide as well.

Okay. And then for CC's second question. She wants to know about the link of IF to diabetes. I am not sure what study she's referring to. I researched, I searched a lot to try and find a study talking about intermittent fasting encouraging diabetes and I think I found it because the study came out, it was in 2018, it was called "Could Intermittent Fasting Diets Increase Diabetes Risk?" It was published in the European Society of Endocrinology. It was one of those studies, Cynthia, how these studies come out and then all the headlines are talking about it. That was the case with this one. What's really interesting is it's no longer on the website, so I can't find the actual study. I'm guessing the study got, was it redacted? What's weird is they don't have a note. It just no longer exists. I'm thinking she was probably talking about that study and I'm thinking something happened with that study to the fact that they don't have it published anymore.

In any case, what it was looking at was it was a study in rodents and they put them on fasting diets and they found that, I think it was an ADF approach every other day, and they found that the rodents did lose weight, but their insulin went up and they gained visceral fat. The conclusion or the hypothesis was that even if fasting was resulting in weight loss, it was actually encouraging diabetes and metabolic issues by its effect on insulin. Stepping back from that well, first of all, like I said the study is gone, something happened with it which is suspect. Moving beyond that, I could not find and maybe I didn't search enough, but I could not find any other studies saying this. The overwhelming majority of literature on fasting is that fasting has a very beneficial effect on insulin, on diabetes risk, on things like that.

For example, a much more recent meta-analysis from 2021 called "Intermittent Fasting: Is there a Role in the Treatment of Diabetes?" A review of the literature and guide for primary care physicians. Like just reading from it, it literally says, "The majority of the available research demonstrates that intermittent fasting is effective at reducing body weight, decreasing fasting glucose, decreasing fasting insulin, reducing insulin resistance, decreasing levels of leptin, and increasing levels of adiponectin. Some studies found that patients were able to reverse their need for insulin therapy during therapeutic intermittent fasting protocols with supervision by their physician. Current evidence suggests that intermittent fasting is an effective nonmedicinal treatment option for type 2 diabetes. More research is needed to delineate the effects of intermittent fasting from weight loss." The long story short takeaway is whatever study CC saw that one or another, I would not be worried about intermittent fasting for increasing diabetes risk. I think the overwhelming majority of data supports the opposite. Cynthia, do you have any thoughts?

Cynthia Thurlow: I do. It's interesting. This is always a good example of cherry-picking research and data mining and the catastrophizing that goes on in the media when people don't know how to read research. I would concur with you that everything that I read and everything that I look at really supports this carb-insulin hypothesis. For someone to somehow suggest that intermittent fasting, which is our ancestral birthright, is somehow going to create pancreatic damage and contribute to diabetes, I think is really dangerous because we as humans are not designed to eat the way that our modern day lives have kind of embraced. It just makes me sad that someone propagated an idea that was picked up by mainstream media that suggested that this would somehow be harmful. In fact, I have Dr. Jason Fung's book sitting in front of me because my intermittent fasting coaches are reading this month.

The Obesity Code talks a great deal about relevant and current research that supports this hypothesis of carbohydrate restriction. That doesn't mean carbohydrates, but I definitely am a fervent believer in carbohydrate restriction for people who are metabolically unhealthy and certainly those that are insulin resistant. I always say knowledge is power and if you know that you are metabolically healthy and metabolically flexible, then you can adjust your carbohydrate consumption accordingly. To suggest that somehow, it's going to damage your pancreas. Type 2 diabetes is a lifestyle disease. Let me be very clear. Type 1 diabetes is an autoimmune destruction of the beta cells in the pancreas, very different. To somehow suggest that nutrition is playing a role in type 1 versus type 2 is unfortunate.

Melanie Avalon: I keep saying it, but I find that really interesting that that study is just gone.

Cynthia Thurlow: Yeah, redacted, and it's probably because it's garbage.

Melanie Avalon: Normally, even if a study is not good, you can still find it. It's still up on the Internet. The fact that it's just gone is very weird, but telling?

Cynthia Thurlow: It's a fascinating development.

Melanie Avalon: Yes, it is. Of course, just to comment on what you were saying about the sensationalization of these findings and such, they're not going to come out and say, "Hey, study was redacted." There's not going to be a whole new swarm where they say that this was undone. If you were saying this, it's concerning that these ideas can get out there that might not be accurate, and they can be just so sensationalized and presented as truth. It's hard to unlearn something that you were exposed to even if it wasn't true because once you hear it. By the way, I'm not discouraging different findings coming out. I'm all for all the different findings and questioning things. It's just the problem comes when most people aren't going to actually look at the source material and think about it and they're just going to listen to or many people I should say most, but many people will just listen to the news and take what they say, which also will be a slightly bastardized version of the original source material.

Cynthia Thurlow: I always say it's the rabbit hole that you have to dive down. Like, someone got excited about some creatine research and they shared it with me and I said, well, it's an N of 26, so the potentiality exists that there might be something worth investigating, but it needs to be statistically significant. That's more often than not what I see is various small sample sizes and then they extrapolate from that and then convince people, "Oh, this thing that you've been doing for five years is no longer healthy." It's like, "Wait a minute, let's look at the data, let's look at the research, let's be thoughtful." And I agree. I hope listeners know that we're always happy to read stuff that's contrary to our own opinions. I think that's part of just being an intellectually curious human being. It's like show me the evidence and let me look at it and then we can decide if it will encourage us to form a different opinion or if it just validates what we already think.

Melanie Avalon: Exactly. I want to know, like, tell me why I'm wrong. That's why I love reading different opinions for me, I love it. I want to know where I'm thinking incorrectly. I would like to know that that would beneficial. I'm not wedded to any one answer or at least as much as I cognitively perceived myself not being wedded to. I know we all have biases that are really hard to see past, but I really do try to be open.

Cynthia Thurlow: Absolutely.

Melanie Avalon: Okie Dokie. Shall we answer another question? This actually relates to what we're just talking about with your creatine. Nikki says "Hi, Melanie and Cynthia. I would love for you to discuss the science behind creatine a bit more, especially after learning Cynthia has a creatine supplement coming out soon, which is actually now out. I have some Thorne brand and try to take it when I remember, but I'll admit it could be a bit more consistent. I'm a questioner under Gretchen Rubin's The Four Tendencies framework, so it helps me to know why when I'm trying to make something a habit. My question is why is creatine necessary even if you're meeting your protein requirements? In my case, 130 to 145 g a day. My other question is, when is the best time to take it? Thanks for all you do."

Cynthia Thurlow: That's a great question, Nikki. What I can tell you is we don't get enough of creatine, let me just back up, our bodies have 70% to 80% less endogenous creatine sources compared to men, so that's number one. Number two is if you look at the research irrespective of life stage, women have differing needs. When you're menstruating at specific times during your menstrual cycle, you can benefit from a little bit more supplementation. I just reviewed a study this afternoon looking at menopausal women and the same could apply to perimenopausal women as they are losing estrogen, they have greater issues with muscle-protein synthesis and so supplementation could beneficial there as well. What I would say is that we don't get enough from animal-based protein because I would love to say just eat more protein. That's not going to do it. We need this specifically for ATP and the muscle so supplementation is going to be very beneficial.

I have personally been using this for over a year, obviously just only recently using my own product because it wasn't available before. My trainer last year started talking to me about it and there's a lot of really good research. Dr. Gabrielle Lyon is 100% on board with the utilization of creatine in women. To me, since a lot of the focus of my work is really talking about metabolic health and maintaining muscle mass, and gosh darn it's so much harder at 51 maintaining muscle than it was 20 years ago. I just never appreciated it. I wanted to introduce something that would be helpful for women throughout their lifetime. I would recommend taking it during your feeding window, not during your fasting window. Melanie and I were talking about this earlier and I was saying I put it into a smoothie and that's how I choose to consume it.

It doesn't have a taste and it's not granular. That's one of the things that the mix ability is high. There was another product that will remain nameless that I've used in the past and it's almost crystallized, so it was harder to get it to blend easily with liquids. That would be my recommendation. And, yes, I am very familiar with Gretchen Rubin's The Four Tendencies framework. I actually was on TV. Yeah, it's interesting. I was on TV with her.

Melanie Avalon: Oh, really?

Cynthia Thurlow: Yeah, when I say on TV with her, when I was at our local ABC affiliate in Washington DC, I got to meet her. At the time I didn't know who she was. I'm embarrassed to admit that. I loved what she talked about so much that I went out and bought the book and every time I worked with a new client one on one, I would give them the quiz.

Melanie Avalon: I feel like I'm so obvious what I am. All I needed was a summary of that book and I was like, yeah, I know exactly what I am.

Cynthia Thurlow: I'm not the questioner. I think I was the upholder, no I wasn't the upholder, obliger.

Melanie Avalon: For listeners, it's whether you uphold inner versus outer expectations. If you uphold inner and outer, so inner being you and then the outer being what other people are asking of you. Let's see if I can remember this. If you uphold both, you're an upholder. If you uphold your inner but not other people's, you're a questioner. If you uphold other people, but not your own, you're an obliger. If you just reject everything, you're a rebel.

Cynthia Thurlow: I really feel like, honestly, I'm a little bit of two. I wouldn't describe myself and I think when I took it, I was kind of on the fence about what direction I headed and I think the younger me would have been the obliger. I was never the rebel, although I've had many rebel clients and then I have to remind myself but the questioners, the ones who always ask a lot of questions, it explains so much and anyone who is comfortable and confident with who they are would never see that as a negative. It's a curiosity piece for me.

Melanie Avalon: Yeah. I agree. For you, I always say either well, I was thinking either a questioner or an upholder.

Cynthia Thurlow: I'm a little bit of an upholder, but I'm not rigid and judgmental. That's the one thing that didn't-- I'm much more I always say I don't use the term libertarian lightly. I'm just saying I just accept people where they are. I'm not particularly judgmental unless you're bad to children and animals. I do have strong opinions, but that's a whole separate conversation.

Melanie Avalon: Yeah, I do think the layer of how you perceive it, I feel like you could withhold or not withhold inner versus outer within the layer of how you, like the judgment layer would be separate. You could be judgmental in all of it or judgmental and none of it. I can see how certain personality traits would probably more likely lead to others.

Cynthia Thurlow: Absolutely. I really like her work and I listen to her podcast and I don't know if anyone else has this issue, but I definitely feel like we need more strong female role model podcasters. Do you feel that way?

Melanie Avalon: It's funny, I was recording just yesterday with Elle Russ, who I adore, and we were talking about because she was the cohost and host of the Primal Blueprint podcast for so long and now she has her own show, The Elle Russ Show. We were talking about the role of women, and yeah, there is like a lack maybe. I guess a lot of the podcasts, I'm just thinking to what I listen to. I guess it is a lot of men.

Cynthia Thurlow: I mean, the ones I listen to, like if I really am honest with listeners, I tend to lean into some of the male ones because my husband was making fun of me because we listened to Huberman Lab all the way to DC and back because Huberman Lab was recording with BioLayne. It was almost a four-hour podcast. It was craziness, but only because I was in the car and my husband was like, "Oh, my God, this is so dry." [laughter] I was like sometimes I just want to learn. I just want to absorb as opposed to just be entertained. I think some of the male-dominated podcasts do a nice job with that. It just depends on my mood. There's definitely there's probably, like, six male-dominated podcasts I lean into, and then I listen to yours. I still need to listen to the glutathione one and a few others, but it's probably more, it's more like male-centric. Not on purpose, but they tend to be more, I don't know, data-driven, less fluff.

Melanie Avalon: Yeah, that's true. I'm just thinking I listen to, well, like Robb and Nicki, so that's both Robb Wolf, Peter Attia. I don't listen regularly to Huberman. I listen to Rich Roll all the time.

Cynthia Thurlow: I need to listen to Rich.

Melanie Avalon: Have you listened to him before?

Cynthia Thurlow: I have not.

Melanie Avalon: This actually speaks to what I was talking earlier about having an open mind. The reason I listen to him primarily is because he's very vegan. He provides a very different perspective because I'm so seeped in the keto and carnivore world. Listening to a vegan-driven podcast I find very helpful and I find him very open-minded. I find him very comforting. He interviews a lot of people that I interview as well, so he interviews people that I'd be listening to anyways. I feel like I get a different perspective coming from him and I just find him very calming. I listen to him at night and I listen to Mikhaila Peterson. I like her podcast.

Cynthia Thurlow: I don't know her.

Melanie Avalon: She's spicy. Jordan Peterson's daughter.

Cynthia Thurlow: Don't know her.

Melanie Avalon: Yeah, she got popular, well, her dad's Jordan Peterson, so that helped. She had a whole thing with carnivores and she went on Joe Rogan and talked about her carnivore experience and that kind of shot her up, so podcasting, I'm just always grateful that I'm in this world because there's so many podcasts I like. Don't take it for granted that we have some amazing podcasts with an amazing audience because it's not easy.

Cynthia Thurlow: No, no. And it's interesting. I'm part of a podcast mastermind and I'm at a different stage in my business and my podcast, so I'm oftentimes giving advice to people in the group, which I lovingly do because I really enjoy this group of women, and I forget how. I don't think we tracked metrics the whole first year we were podcasting. Really, I didn't start taking podcast metrics seriously until Kelly and I, so Everyday Wellness used to be a co-hosted podcast with a friend of mine who's a clinical psychologist. It was kind of her idea and then a little bit over a year in she was less interested in doing it, and it was either sink or swim. It wasn't until 2020 that I started paying attention to those things. I said, okay, I'm going to swim, I'm not going to sink, I'm not going to turn this over. From my perspective, I think that loving what you do is certainly very evident.

I know Gin and you created this amazing community of which I'm very grateful to be a part of, and then our own ecosystems that are separate from Intermittent Fasting podcast. There's no doubt that your podcast in particular is, you do a fantastic job interviewing people and exposing me to new information, new ways of thinking about things and that's really what it's all about.

Melanie Avalon: Yeah, no, I as well, I'm so inspired by everything that you're doing. It's so incredible. It's almost eerie the overlap, well, we have a lot of overlap in our guests and who we interview and everything, but we also have different like, I feel like yours is more menopausal and women's issues and hormones skew and then mine is just like all over the place, like deuterium-depleted water.

Cynthia Thurlow: I think mine is skewed because I know that nothing prepared me for being middle aged, and it's not like intellectually I wasn't prepared, but no one had talked to me about the things that were going to happen. I'm like if my experiences can help someone else and if I can bring on guests that can speak to that, I mean, I know my listeners and I know what's going to resonate. I know I can offer alternative perspectives, but I know what content is really going to resonate. It's been validated so frequently that now I don't ever want to be an echo chamber because as an example I had that scientist talking about that form of tocotrienols, annatto and how that can be helpful for bone health, which I think is significant for all of us. I never would have imagined that his research would really like resonated steeply.

Like, I watch all my metrics, I'm a little OCD about it. I only do it once a day, but I know exactly what content resonates and perimenopause and menopause are women north of 35. That's really who we speak to. I think that you bring on guests that have got a very wide, diverse opinions, and I think that's wonderful. I think it's important for all of us to not be an echo chamber because it's easy just to stay stuck in one spot.

Melanie Avalon: Yeah, so incredibly true. All the more knowledge, all the more things the merrier. I imagine I probably will, when I get to that point in my life, have a much uptake and interest, and I'm interested in it now. Just what you were talking about with what you experienced and the focus there.

Cynthia Thurlow: Oh, goodness. I want everyone to avoid what I did. I hit the wall and I thought I was doing everything right. I'm completely sensitive to when people tell me I don't know what I'm doing wrong. I'm like, "Oh, it's all hormones."

Melanie Avalon: I was talking about this with Elle yesterday. Having gone through health issues really can be a benefit because A, it makes you learn so much about the topic and gives you agency to take care of yourself and feel better, but then also just gives you complete empathy for other people having similar things.

Cynthia Thurlow: Absolutely.

Melanie Avalon: I feel you people when you're struggling.

Cynthia Thurlow: Benefit from what we've learned that's what I would say for everyone.

Melanie Avalon: Hi, friends, exciting announcement. You guys know I love blue light-blocking glasses. I wear them every single night of my life. My favorite blue light-blocking glasses company, Bon Charge, is having a massive 25% off sitewide sale until January 2. Now is the time. I am often asked what are my favorite, "Biohacking products?" Something I truly, honestly cannot imagine my life without our blue light-blocking glasses. In today's modern environment, we are massively overexposed to blue light. It's a stimulating type of light, which can lead to stress, anxiety, headaches, and in particular sleep issues. Blue light actually stops our bodies from producing melatonin, which is our sleep hormone. Our exposure to blue light can completely disrupt our circadian rhythm, make it hard to fall asleep, make it hard to stay asleep, and so much more. Friends, I identify as an insomniac. I would not be able to sleep without my blue light-blocking glasses. I also stay up late working and wearing blue light-blocking glasses at night has made it so I can do that and still fall asleep. My absolute favorite blue light-blocking glasses on the market are Bon Charge, formerly known as BLUblox. 

Bon Charge makes an array of blue light-blocking glasses in all different designs, so you can truly find something that fits your style and reap all of the benefits of blue light blocking. They have clear computer glasses. You can wear those during the day, especially if you're looking at screens all day to help with anxiety, headaches, and stress. They have their light sensitivity glasses, those are tinged with a special yellow color scientifically proven to boost mood and they block even more blue light. Those are great for the day or evening. Then they have their blue light-blocking glasses for sleep. Those are the ones that I put on at night while working before bed. Oh, my goodness, friends it's something you truly have to experience. You put on these glasses and it's like you just tell your brain, “Okay, it's time to go to sleep soon.” They also have amazing Blackout Sleep Masks. Those block 100% of light with zero eye pressure. I wear this every single night and I don't know how I would sleep without it. I'm so thrilled because Bon Charge is currently having a Boxing Day sale, which is 25% off sitewide until January 2. Just go to boncharge.com and choose your favorite wellness products and the discount code will automatically be applied at checkout. That's B-O-N-C-H-A-R-G-E dotcom and the 25% off will automatically be applied at checkout. If you're listening after the sale ends, you can use the coupon code IFPODCAST for 15% off and we'll put all this information in the show notes.

All right, shall we go on to our next question?

Cynthia Thurlow: Sure. "Hi, ladies. New to intermittent fasting and I'm slowly working my way through your fantastic and informative podcast. I am a 24-year-old lean male who is looking to move from 14% body fat to 10% and really get those abs popping for summer. I have followed calorie restriction for a year with no consistent and lasting results. I exercise six times per week, badminton, squash, HIIT resistance training, and football and I'm worried my calorie deficit is too large. I eat approximately 1500 calories per day regardless of how much intense cardio I do. Am I in danger of losing muscle or any other adverse health effects of a deficit that is too large? I eat 10:30 AM to 6: 30 PM and have the above commitments in evenings to start my fast with exercise. Will this also get me into ketosis faster, by starting the fast with exercise? You are both awesome and keep up the good work. Many thanks, Alex."

Melanie Avalon: All right, Alex, thank you so much for your question. You're a 24-year-old male, already lower body fat, doing a massive amount of exercise, and eating a very calorie-restricted diet. I'm guessing that you're doing the calorie restriction because you are trying to achieve these certain goals, which completely makes sense. I am all for people going for whatever goals they want to go for. So, I support in that aspect. That said, I would definitely focus on adequately fueling yourself. I would be worried about losing muscle from that deficit because how long you said you've been doing calorie restriction, for a year with no consistent and lasting results? This is my suggestion, but I would have a complete mindset shift with the food. I would stop counting calories. I would eat to satiety. I would let fasting do its magic. If you are going to focus on something food wise, I would focus on the macronutrient aspect of things, especially if you're pursuing certain body fat goals.

I would focus on protein. Making sure that you're getting adequate protein, especially if you're concerned about maintaining muscle and not losing muscle. From there you can get a lot of benefits. I say this all the time, but you can get a lot of benefits by doing either lower carb or lower fat. There's a lot of metabolic magic that can happen when you're playing with the macros and not restricting calories. You've been doing this for a year. It's a very severe calorie restriction and it's not working. So, I would not keep doing it. I would definitely mix things up. As far as will you get into ketosis faster by starting the fast with exercise? Yes and no, so quite probably you will burn through your glycogen faster and potentially enter ketosis faster. The only slight difference is you could be doing very glycolytic-demanding activity. The actual exercise itself might be a carb-fueled workout if that makes sense. On the flipside, in theory, you should be entering ketosis faster. Do you have thoughts, Cynthia?

Cynthia Thurlow: I do. I'm genuinely concerned about the restriction of macronutrients, especially if you're working out six days a week, which is pretty dedicated and intense, and you're doing two days of strength training and you are very likely putting yourself in a position that you are not going to be able to maintain muscle mass. Your body will probably catabolize some of your muscle to make up for the lack of macronutrients you're consuming. Ted Naman talks a great deal about thin people doing this and I always refer to it as the triad, the over fasting, overexercising, over restriction of food. I think we can unknowingly get into some trouble when we're eating in a deficit for too long a period of time. At a minimum, I think that you need to back off on the fasting. I would imagine that simply by maybe swapping out some cardio for some strength training and being very targeted with your macronutrients, especially protein and appropriately timed carbohydrates could allow you to get to the point where you could lean out.

I think at this point you're leaving your body in a deficit where it's depleted. As I mentioned earlier, I think you're putting yourself in a position where you're going to end up catabolizing or breaking down your muscle to fuel your body. Certainly 24 years old if your testosterone is optimized or growth hormone, et cetera, you really don't want to be putting yourself in a deficit like that all the time. I would definitely back off on the intensity work on a recovery day. Maybe instead of doing HIIT and all that explosive movement, give yourself another dedicated day of strength training. I would have three meals a day to make sure you're getting at least 1 gram per pound of ideal body weight of protein because I would imagine you're depleted all the time.

Melanie Avalon: This is like a massive, massive deficit.

Cynthia Thurlow: That triad, I talk about, jokingly people are like, what's your next book going to be on? I'm like it's not going to be about the triad, but I'm starting to talk more about it, this over fasting, overexercising, over restriction, which ends up depleting your entire endocrine system and can put people in some situations where they're heading in the opposite direction. High cortisol, which can lead to high insulin, high blood sugar. This is when you see people that they don't understand the interrelationship of all of these hormones when their body is in a chronically stressed, sympathetic, dominant state.

Melanie Avalon: Well, this has been absolutely wonderful. By the way, Cynthia, my face is completely numb right now. It was like slowly, like, numbing during the show. I was like, "Well, what is happening?" This has been absolutely wonderful though. For listeners, if you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. You can get all the stuff that we like at ifpodcast.com/stuffwelike. Do we mention your link, Cynthia? How do people get creatine?

Cynthia Thurlow: www.cynthiathurlow.com/creatine.

Melanie Avalon: And for the berberine, avalonx.us/berberine. And you can follow us on Instagram, we are @ifpodcast, I am @melanieavalon, Cynthia is @cynthia_thurlow_. This has been absolutely wonderful. I will talk to you next week. 

Cynthia Thurlow: Sounds good. Enjoy your appointment.

Melanie Avalon: Thank you. Bye.

Cynthia Thurlow: Bye.

Melanie Avalon: Thank you so much for listening to The Intermittent Fasting Podcast. Please remember everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team, administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and re-composed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Dec 18

Episode 296: Berberine, Insulin Sensitivity, Glucose Control, Gut Health, Liver Health, Body Recomposition, AMPK Activation, Cholesterol Control, And More!

Intermittent Fasting

Welcome to Episode 296 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

 JOOVV: Like intermittent fasting, red light therapy can benefit the body on so many levels! It literally works on the mitochondrial level to help your cells generate more energy! Red light can help you burn fat (including targeted fat burning and stubborn fat!), contour your body, reduce fine lines and wrinkles, produce collagen for epic skin, support muscle recovery, reduce joint pain and inflammation, combat fatigue, help you sleep better, improve mood, and so much more!! These devices are literally LIFE CHANGING!! For A Limited Time Go To Joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

AVALONX MAGNESIUM 8Get Melanie’s Broad Spectrum Complex Featuring 8 Forms Of Magnesium, To Support Stress, Muscle Recovery, Cardiovascular Health, GI Motility, Blood Sugar Control, Mood, Sleep, And More! Tested For Purity & Potency. No Toxic Fillers. Glass Bottle. Avalonx Supplements Are Free Of Toxic Fillers, Common Allergens, Heavy Metals,  Mold, And Triple Tested For Purity And Potency. Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist, And Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

LMNT: For Fasting Or Low-Carb Diets Electrolytes Are Key For Relieving Hunger, Cramps, Headaches, Tiredness, And Dizziness. With No Sugar, Artificial Ingredients, Coloring, And Only 2 Grams Of Carbs Per Packet, Try LMNT For Complete And Total Hydration. For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

JOOVV: For A Limited Time Go To joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

scotts backstory

GMP certified

Episode 265: All About Supplements With Scott Emmens, The Supplement Industry, Purity, Potency, Testing, Toxins, Authenticity, Organics, Common Additives, And More!

Continuous glucose monitos

Go To melanieavalon.com/nutrisensecgm And Use Coupon Code MelanieAvalon For $30 Off!

metformin

combining berberine with metformin

the types of anti-diabetic medications

the benefits of berberine

what is berberine?

AVALON MAGNESIUM 8: Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

the history of berberine

the effect on the GI tract

dosing

The Melanie Avalon Biohacking Podcast Episode #93 - Shawn Wells

The Melanie Avalon Biohacking Podcast Episode #166 - Megan Ramos

the contraindications

meal timing

body Composition

AMPK activation

positive effects on the liver

dihydroberberine

LMNT: For A Limited Time Go To drinklmnt.com/ifpodcast To Get A FREE Sample Pack With Any Purchase! Learn All About Electrolytes In Episode 237 - Our Interview With Robb Wolf!

the journey of creating the supplement

purity testing

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 296 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: A 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time and get ready for The Intermittent Fasting Podcast.

Hi friends, you guys know how seriously I take my health routine. That is probably the understatement of the year. One of my literal non-negotiables that I talk about all the time that I use every single day of my life is getting my daily dose of red-light therapy. For years now, yes years, I've been using Joovv and I love it because it is so relaxing and so easy to use. You've probably heard me talk about Joovv before that's J-O-O-V-V. I use my devices daily to support healthy cellular function, which is the literal foundation of our health. If you've heard any of my episodes on mitochondrial health you know this is true. Having healthy cellular function helps give me peace of mind that my body is working efficiently and has the energy that it needs to get through the day. There are so many clinically proven benefits from red light therapy and I have personally so experienced many of them. I use the red light to naturally regulate my circadian rhythm. I wind down with it at night and wake up in the morning with it. Whenever I have any muscle pain or soreness. I shine my Joovv red light on it and the pain instantly goes away. It's actually shocking. I love it for skin health, it makes my skin glow. And you can also use it for things that I originally got into red light therapy for which was supporting my thyroid. Yes, I struggle with hypothyroidism and supporting hair growth. Aside from the benefits, I've been recommending Joovv for years because the quality of their devices is simply the best. Their modular design allows for a variety of setup options that gives you flexibility plus the treatments are easy and can be done in as little as 10 minutes. Although I tend to run mine all day as ambient light. All you have to do is relax and let your body take in the light. Joovv offers several different size options including a wireless handheld device called the Joovv Go. That is amazing for targeting specific areas around your body like hurting joints or sore muscles.

When I traveled recently and had torn something in my knee, I brought my Joovv Go with me, game changer, I don't know how I would have survived the trip without it. Health doesn't have to be complicated and Joovv makes it simple by helping what matters most, our cells. So, go check out the Joovv today and while you're there, Joovv is offering all our listeners an exclusive discount on their first order. Just go to joovv.com/ifpodcast and apply the coupon code, IFPODCAST to your qualifying order. Again, that's joovv.com/ifpodcast with the coupon code IFPODCAST. Pick up a Joovv today, some exclusions do apply and we will put all of this information in the show notes.

And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting, it's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer, and obesogens which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream.

And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup may be playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of future generations. That's because ladies when we have babies, a huge percentage of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years.

Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means when you put on some conventional lipstick, 30 years later maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life and their makeup is amazing. Check out my Instagram to see what it looks like. Tina Fey even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well. 

And lastly, if you're thinking of making clean beauty and safe skincare a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally completely worth it. So, again to shop with us go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show.

Hi everybody, and welcome. This is episode number 296 of The Intermittent Fasting Podcast. I'm Melanie Avalon and I am here with a very special guest today, quickly becoming a crowd favorite. I am here with Scott Emmens. He is the chief operating officer and cofounder of MD Logic Health, which is an incredible supplement company that you guys are quickly becoming very familiar with because they are actually my partner in bringing you AvalonX. So, serrapeptase and magnesium that we've had and Scott is back here today. Well, first of all, because he's basically one of my favorite people in the entire world and I mean that from the bottom of my heart. But secondly, I am thrilled that we are about to launch-- actually when this comes out, we will have just launched my third AvalonX supplement. And it is something that I already personally had been taking every day in my life. Not only that, but it's something I've talked about on this show so, so much. Since this show is The Intermittent Fasting Podcast, it is something that really relates to metabolic health, blood sugar levels, how well you can do your fast, and then on top of that so many other health benefits that I actually didn't even really realize until sitting down to make my own version of this supplement. And that is berberine. I've been looking forward to this episode for a long. Scott, thank you so much for being here.

Scott Emmens: Hi, Melanie, thank you for having me on the show. I'm thrilled to be on and even more excited that we're you're finally launching berberine.

Melanie Avalon: I know, I feel like this has been such a long time coming. Okay, a lot of our audience is probably familiar with you because you've actually been on the show twice before you came on. We did a whole episode on magnesium with Cynthia. And then more recently, you did an episode with Cynthia for her creatine supplement because Scott also partners with Cynthia for her supplement line. Basically, we just really love Scott. But for those who are not familiar, Scott, super briefly, could you tell your backstory?

Scott Emmens: Sure, for those folks who may not have heard the first podcast when we went through that. I was in the biotech and pharmaceutical space for 25 years in a variety of positions, in marketing, sales, and sales leadership. I eventually got out to manage market side as well as operations and operational side. I really basically worked at some of the biggest pharma companies that people have heard of Takeda Pharmaceuticals, AstraZeneca pharmaceuticals, which was at the time part of Merck, Shire, and then became a startup expert, and worked my way into the C-suite of multiple pharmaceutical companies. And I really kind of around 2018 decided I was going to start my own biotech company and did that, very successful and literally right around 2020, when the pandemic first started, I'd decided that I really wanted to get into the wellness space. And we had sold our biotech company and I had three partners. And we decided, my partner and I, at the time thought, "Let's do a wellness line, make a wellness company." We had a connection with one of the largest US manufacturers. He is a partner in MD Logic as well. And we really just both believed in making people and keeping people well and letting them optimize their life through supplemental nutrition.

Melanie Avalon: Yeah, that's something that I really, really love working with you is you have seen the industry side of things. You know what you're doing. I have learned much and creating the supplement line, just what goes on in the supplement creation world, and how creating our own supplement line that is not a pharmaceutical, how it compares to that. And also, all of the crazy practices that go on in this industry it's a little bit shocking.

Scott Emmens: Yeah, it can be and I think that's where my pharmaceutical background really helps is making sure that we're going to do everything by the book. And by the book meaning people often see GMP on their label, it'll say GMP or GMP certified. And what that stands for is "Good Manufacturing Process." That's a compiled document from the FDA of very specific things you need to do, both in terms of the manufacturing of the product, the storage of the product, the cleanliness of the machines, the raw ingredients, the testing of the raw ingredients, as well as a number of other things including how you label even down to the font size of the label. And then including, of course, what you say about the product and how you make claims and that's where people tend to get in trouble.

We try to make the absolute best product we can. We have a great process for GMP. We have been audited by the FDA as most GMP companies are about every other year or so, and have a pristine track record and I am here to make sure that your supplements and MD Logic health supplements maintain that pristine record of both incredible quality, testing, and maintain the highest standards of GMP or above.

Melanie Avalon: Yeah, I am do grateful for this because honestly my goal in making supplements was, I knew I wanted to make the very best on the market. And it has been so refreshing to have a partner like you who is in line with that. And even every time I send my emails or I'm creating my content to promote the different supplements, I've come up with my list of basically the qualities about the AvalonX supplements. I say at the beginning that these are the only supplements on the market that are all of these things. And to my best of my knowledge, that's true. They're the only ones that are tested multiple times for purity and potency, free of all allergens. Scott and I have gone to great lengths to get rid of problematic fillers from the supplements, which has been a whole journey on its own, especially revisit, I'll put a link to it in the show notes the episode that we did on--. No, wait, "We haven't done the episode and serrapeptase yet, did we?" I think we talked about it though.

Scott Emmens: I think we did talk about it? But I've to go back into my memory log. But I believe we did talk about the serrapeptase, yeah.

Melanie Avalon: Did you come on this show for serrapeptase?

Scott Emmens: I think this might be my third appearance. I think I did do the serrapeptase first, then the magnesium, and then creatine. Yeah, I think serrapeptase was the very first one.

Melanie Avalon: My bad. So, this is your fourth time back?

Scott Emmens: Oh my goodness, how time flies. [laughs] 

Melanie Avalon: Oh, and you're having fun. [laughs] Okay, wait. In any case, listen to the serrapeptase episode if you want to hear the craziness with the fillers and the lubrication agents and also something that's incredible that really I think makes us stand apart is they are in glass bottles, which is very rare and unique in the supplement world. It's just been an amazing journey. "Shall we talk about our berberine journey?"

Scott Emmens: Let's talk a little bit about the berberine journey, I think the audience would love to hear what transpired? Why did it take us so long? And yeah, why don't you kick it off now?

Melanie Avalon: Okay, I started taking berberine when I started wearing something that our listeners are probably pretty familiar with which is the continuous glucose monitor. Just briefly a continuous glucose monitor is you put it on your arm, and it gives you a basically 24/7 look at your blood sugar levels. It is so eye-opening, so fascinating. Because when you're getting just doing a finger prick or yeah, a finger prick or blood draw for your blood glucose that's really just a snapshot in time. And it's not very telling of what is happening consistently. If listeners who like to get a continuous glucose monitor, you can go to nutrisense.io/ifpodcast and the promo code IFPODCAST will get you $30 off any subscription program to a NutriSense CGM, so definitely check that out. But in any case, doing a CGM really made me look more at my blood sugar levels and that's when I wanted to see what I could do to help lower it.

Berberine is considered to be the go-to "Natural Supplement" to address blood sugar levels. The go-to pharmaceutical to address blood sugar levels is metformin. There have been multiple studies comparing metformin to berberine and finding similar effects, which is incredible. So basically, berberine can be comparable to metformin in lowering blood sugar, lowering HbA1c, which is a longer term picture of your blood sugar levels and also lowering insulin without any of the potential side effects of metformin or the other negative side effects that can come with other metabolic health blood sugar controlling agents.

Scott Emmens: Certainly, I think that's absolutely correct. One thing we want to caution and make certain that we're not giving medical advice nor are we suggesting that anyone replace their metformin with berberine, not at all. What we are saying is that berberine has some remarkable properties and there's a lot of data, in fact, it's one of the most studied herbs or alkaloids out there. And we really feel passionate about all the benefits. In fact, I was stunned to see how many benefits there are with berberine as we really dug into the research, but again, we just want to caution, never add anything or take anything away, especially metformin for diabetic patients. So, just want to make sure that that's perfectly clear.

Melanie Avalon: Oh, yeah, I'm so glad you said that. And that's actually really appropriate because we got a lot of questions about that, Karina said, "How is it different than metformin?" Marie said, "Can you take it while taking metformin?" and Lea said, "Can it be taken if one is already on metformin, can it be taken instead of metformin?" So, just to dive deeper into all of that and to what Scott just said? Metformin as well as some other drugs that are used for similar purposes can have side effects. Metformin notoriously has gastrointestinal discomfort. Metformin cannot be used by diabetics or liver disease, renal impairment or cardiopulmonary insufficiency, and then some other related drugs like I don't even know how you say it. Is it pio?

Scott Emmens: Pioglitazone. I know that one because I sold it.

Melanie Avalon: I was like "Scott probably knows it."

Scott Emmens: Pioglitazone or pioglitazone.

Melanie Avalon: So, that one can increase the risks of distal bone fractures, bladder cancer, and edema. Here's another one Scott, sulfonylur--

Scott Emmens: Sulfonylureas?

Melanie Avalon: Yes, yeah, that was linked to hypoglycemia, weight gain, and cardiovascular damage. When we compare this to berberine, very little if any side effects, some people do have some GI issues potentially in the beginning, which we can talk about. But we can definitely dive into that. Because ironically, even with GI issues, berberine has a ton of potential benefits for GI Health. But besides that, you basically get all of the benefits of blood sugar control with a myriad of other benefits that we're going to talk about without the potential negative side effects of these pharmaceuticals. And there have been like Scott said, "We are not saying to stop your medications. We're not saying to even add this to your medications, that's something you would want to talk with your doctor about." Anything that you're doing, playing with your medications, definitely work with your doctor. That said, there's actually been quite a few studies looking at berberine in combination with metformin and finding beneficial effects, potentially that it might be a better approach, not saying to do this, work with your doctor. But potentially that combination therapy might be better than metformin alone because you can get more of the benefits with less of side effects.

Scott Emmens: Just going to add to that to just make sure that people make certain that if you add berberine to an antidiabetic, it can cause hypoglycemia. That's something you want to be cautious. Whatever the side effects of your prescription medication are, you want to let your physician know that you're going to take berberine and get their permission, make sure that the drugs you're on are not going to interfere with it because some drugs can have hypoglycemia on their own, when you add something like berberine, it can increase that potential. That's something people have to be very cautious of. Hypoglycemia can be a life-threatening condition as those folks who've had it know. It's interesting Melanie, the three drugs you mentioned, metformin which is sort of the gold standard, about 80% of diabetics are taking metformin or what used to be called Glucophage, the brand name, pioglitazone or TZD as they're known, which is an insulin resistance molecule, works on PPARalpha and PPARgamma. And then you mentioned was sulfonylurea which actually works on the pancreas to secrete more insulin. So, each one of those works differently. Metformin primarily works on the liver preventing gluconeogenesis and a little bit of insulin resistance. Then there's a TZD class pioglitazone, that works primarily on insulin resistance. And then there is some sulfonylurea class which increases your pancreas' output of insulin. They all work in different ways and they can all have different interactions with berberine, so again always talk to your physician. I think the real benefit Melanie is that berberine doesn't-- you don't have to have high blood sugar or you don't have to have diabetes to benefit, in fact, the real benefit we want to talk about today is what is the benefit for just people in general that want to optimize their health and optimize their cellular function and their energy. And that is where berberine shines.

Melanie Avalon: First of all, that was highly impressive, that you knew all of that. [chuckles] "I'm so impressed." Okay. Yeah, I'm so glad you said that because that is the exact same page that I'm on. And like I said, I came to it originally for blood sugar control and I think that's why most people think about it and it's a great reason to take it, but there are so many other benefits like whole body benefits. So, the questions we had, very simple, Kersey said, "Why do I need it?" Jennifer said, "What are all the benefits that come from taking it?" Amy said, "Will it help with insulin resistance?" And then what we will also get into Paul said, "Wondering what other health benefits it offers besides blood sugar regulation?" Andrea said, "Does it have any other benefits besides preventing lessening glucose spikes." So, we can dive deep into all of that. But to start off, I would like to give an overview of how it does work for blood sugar control because I think that really speaks to why it can be really beneficial to take when you understand that it's not like a pharmaceutical where-- With the pharmaceuticals they typically have a more singular approach to why they're working, compared to berberine that has all of these effects that can create this metabolic health.

For the blood glucose control, like Scott had mentioned it can be used for addressing insulin sensitivity and reducing blood sugar. It's so interesting because there are many studies. I had much fun preparing for this because there are many different hypotheses for how it's doing that. One of the main mechanisms and Scott mentioned this is that directly in the liver, it actually can reduce the liver's ability to actually create glucose or like create glucose and release it into the bloodstream. Because a mind-blowing fact-- I remember when I first learned this and it blew my mind because I think most people don't realize this, is that when people have high blood sugar levels most people think it is from what they're eating, which it is, but the actual, like 24/7 higher blood sugar levels, that's mostly being controlled by your liver. So, it's your liver creating glucose and releasing glucose.

Berberine actually inhibits that, it reduces enzymes directly in the liver that do that process, so then it can't happen. And interestingly, they have found that even though it helps insulin sensitivity, it doesn't seem to actually affect insulin production in the liver, so it's working independently of that which is really interesting. It can actually be directly in the gut reduce intestinal glucose absorption. So, just starting at the very beginning, it can stop the glucose from actually entering the body in the first place and that's by inhibiting a specific enzyme called a glucosidase activity. And that's an intestinal enzyme that actually digests carbs and converts them into more simpler sugars. Stopping that keeps you from actually absorbing some of those carbs in the first place. And then, beyond all of those enzymes and such it also can actually affect the transport of glucose throughout the body. And then on top of that, we can talk about the gut health potential of it. But a lot of researchers have hypothesized that its beneficial effects on the gut microbiome actually have a secondary effect of blood sugar control by the metabolic health state that is created from that so the anti-inflammatory state, the encouraging of short-chain fatty acid butyrate-producing bacteria when butyrate is created and gets into the bloodstream, it actually can help with glycemic control and the reduction of inflammation in the gut from endotoxin and LPS and the recruitment of macrophages and I realized I say all these words really fast and I know what they mean, but people might not know what they mean, so that's basically like the toxic byproducts that are created from "bad bacteria," because I realized saying good and bad bacteria can be a little bit simplistic. It reduces the inflammatory potential of the gut and inflammation is a key driver in metabolic issues. I can stop there a little bit. So, you want to jump in at all, Scott?

Scott Emmens: Well, first of all, great, I think it's a fantastic overview. And you can see how many different complex mechanisms berberine appears to have and why it has a broad base of positive impact across a number of organs and organ systems and then in particular blood sugar. I think we're going to learn a lot more as this molecule is again becoming, I shouldn't say molecule, this plant alkaloid is becoming hot on people's radar again. And I think at the end of the day, insulin is such a powerful hormone that when you can maintain blood glucose, which your audience is all about, the intermittent fasting audience really understands what blood glucose is about. But I don't know that we talk about the power of insulin and how powerful it is. I don't know if berberine lowers your fasting insulin and/or postprandial insulin meaning after a meal. My guess would be yes because it's lowering blood glucose with people that are already in normal ranges, well, then it's going to probably lower your insulin.

And we know in the presence of insulin, it's more difficult to burn fat, so it's all these different ways in which it slows the breakdown of glucose, it slows the liver's export or gluconeogenesis creating new sugar to push out into the bloodstream. All of the different mechanisms I think are fascinating and the more we learn about it, I think the more we're going to realize that this compound is going to have some very significant overall benefits for your wellbeing on a number of different organ systems.

Melanie Avalon: I'm glad you said that. Two things to comment on, the insulin piece. I did find studies showing a reduction in insulin. It was once where they were comparing it to metformin and they were looking at the long-term effects of that. And then there are so many studies talking about how it increases insulin sensitivity, that is definitely happening. But I'm so glad you said that because we probably should start with a really important question or we should get to a really important question. Jennifer said, "What is it? Is it a plant, a fruit, etc.?" April said, "I know serrapeptase comes from silkworms, but where does berberine come from? When did people start using it?" I realized we were saying like we haven't really defined what it is. So, it is a plant alkaloid and Scott, would you like to talk about the plant that it comes from? And why we chose the one that we chose?

Scott Emmens: There are different forms of berberine based on the plant source that it comes from. The one that's being used in our Vedic Medicine in India and is usually the form that is used in most of the studies you're going to see and I hope I pronounce this right, but it's Berberis Aristata I believe and that's spelled B-E-R-B-E-R-I-S A-R-I-S-T-A-T-A and that is the form that we've used and that comes from the Indian barberry tree or shrub and it is a shrub that belongs to the genus Berberis and it is found specifically in India. And there are many different species of this shrub. And it's typically found in the Himalaya area of India and Nepal as well as other places in Sri Lanka and that is the form that we’ve utilized.

Melanie Avalon: Hi, friends. I'm about to tell you how to get 10% off my new magnesium supplement. Yes, exciting news. My Magnesium 8 Broad Spectrum blend is here. Magnesium is such a crucial mineral in the body. It's involved in over 600 enzymatic processes. Basically, everything that you do requires magnesium including creating energy from your food, turning it into ATP in the mitochondria, boosting your antioxidant system. Magnesium has been shown to help with the creation of glutathione regulating your blood sugar levels, affecting nerve health, muscle recovery, muscle contractions, supporting cardiovascular health and blood pressure, aiding sleep and relaxation, and so much more. It's estimated that up to two-thirds of Americans do not get the daily recommended levels of magnesium and on top of that magnesium deficiencies can often be silent because only 1% of magnesium is actually in our bloodstream. So that might not be reflective of a true magnesium deficiency. Our modern soils are depleted of magnesium, we're not getting it in our diet. That's why it can be crucial to supplement with magnesium daily. I wanted to make the best magnesium on the market and that is what Magnesium 8 is. It contains 8 forms of magnesium in their most absorbable forms, so you can truly boost your magnesium levels. It comes with the cofactor methylated B6 to help with absorption as well as chelating manganese because magnesium can actually displace manganese in the body. My AvalonX supplements are free of all problematic fillers including rice, which is very very common in a lot of supplements including some popular magnesium supplements on the market. It's tested multiple times for purity and potency and to be free of all common allergens as well as free of heavy metals and mold and it comes in a glass bottle to help prevent leaching of toxins into our bodies and the environment.

Friends, I wanted to make the best magnesium on the market and that is what this magnesium is. You can get Magnesium 8 at avalonx.us and use the coupon code MELANIEAVALON to get 10% off your order. That code will also work on all my supplements including my first supplement that I made, serrapeptase, you guys love serrapeptase, a proteolytic enzyme created by the Japanese silkworm that breaks down problematic proteins in your body and can help allergies, inflammation, wound healing, clear up your skin, clear brain fog, even reduce cholesterol and amyloid plaque. All of this is at avalonx.us, that coupon code MELANIEAVALON will also get you 10% off sitewide from my amazing partner MD Logic Health. For that just go to melanieavalon.com/mdlogic. You can also get on my email list for all of the updates. That's at avalonx.us/emaillist. I'll put all this information in the show notes. All right now back to the show.

Do you know when they started using berberine?

Scott Emmens: I'm going to take an educated guess-- Because our Vedic Medicine goes back a while, I'm going to take an educated guess and say 1500 years ago.

Melanie Avalon: 3000 BC.

Scott Emmens: Wow.

Melanie Avalon: To treat diarrhea and dysentery. That's like when I very first started, isn't that crazy? That has a long safety record, I will say [chuckles] which we can circle back to.

Scott Emmens: So, I was only off by 4000 years, not bad. [chuckles]

Melanie Avalon: It probably got upregulated more little bit later when it first appeared. And like I said, that was to treat diarrhea and dysentery. And just to circle back a little bit to the GI Health aspect to really fill that out. There's been many studies on berberine and its effect on gut bacteria. And actually, we have a question about this, so I'll just tie that in right now. For example, Nikki said, "I've heard people say not to take it daily because it changes your gut bacteria, what are your thoughts on that?" Morris said, "This would be my question. I always cycle on and off of it, but I know Melanie does not?" And then Karen said, "Berberine is used as an herbal antibacterial/antimicrobial, which I was going to get to, so I'm glad she said that." She said, "In addition to the blood sugar lowering properties that you are focusing on, I'm concerned about negative effects on beneficial gut bacteria with regular use of this product, can you speak to that?" I'm super happy that people were asking me about that. There have been a lot of studies looking at its effect on gut bacteria populations, and across the board it tends to increase the "Positive good bacteria, specifically Bacteroides and decrease the more inflammatory bacteria specifically Firmicutes." Because those are the two that if you know about gut microbiome, you might have heard of them before, but there's been a lot of other studies, for example, it's directly antibacterial against E. coli and clostridium difficile. It can increase, I mentioned this earlier, the short-chain fatty acid-producing bacteria, specifically and I don't know if I'm going to say these right. Phascolarctobacterium, Anaerotruncus, and Acidobacteria, those are all short-chain fatty acid-producing bacteria that can help with intestinal integrity. And it also may inhibit a certain type of bacteria that has been connected to obesity, which is super cool. And we can actually get into the obesity, body fat bit in a little bit. Basically, it seems to have a very beneficial effect on gut bacteria. I would not be personally and again you can make your own decisions and choices, but I personally am not concerned about the effect because it seems to have a very beneficial effect. I actually wonder, Scott, I'd be curious about your thoughts on this, I hypothesize that people who might sometimes be experiencing negative side effects in the beginning, it might be because they are playing with the populations of their bacteria and are experiencing a die-off effect because whenever you go after the bad guys, you can get negative side effects from that. It's a good thing because you are moving the needle towards more beneficial population. There might be some side effects in the interim. And, for example, I found there was one study looking at berberine compared to metformin and it found that all of the side effects only happened in the very beginning of the trial, and there's a longer-term trial. if you are experiencing gut issues in the beginning, I would suggest maybe lowering your dose so we can talk about this later and maybe sticking it out a little bit. But Scott, what are your thoughts?

Scott Emmens: I think your hypothesis is a pretty good one. Meaning anytime you're detoxing the body even if detoxing is a "Good Thing, " you know that you're killing off a lot of bad bacteria, and maybe you're not using a binding agent or you've got a lot of bad bacteria in your gut that could cause inflammation, the destruction of those can release toxins. Yeah, that could very well be, I think, that's a little speculative, but it's a reasonable theory. But what is pretty consistent is that the metformin side effects and the berberine side effects both seem to happen upfront. And the solution to that in the Glucophage world, is what doctors will say and many patients have probably heard this wording "Start low and go slow." if you are sensitive, you've never taken berberine before or you take two pills on day one and you feel a little bit of GI upset then back down to one capsule 500 mg once a day, kind of stabilize yourself and then you can work your way up. And that's really, I think, always goes for any medication or supplement, you always want the lowest effective dose. Now, we came out with the 500 mg, had a lot of discussion about what to recommend in terms of dosing, one to three capsules a day is where it landed because the majority of the data suggests that on the low end, 500 mg is right. On the higher end, 15 mg is correct. Many of the studies have been done with 500 mg three times a day, I don't think you want to take 1500 in one shot, really, you want to break that up over three doses. But that's where we found the sweet spot was. So, if people are experiencing side effects, I would say start with 500 and just slowly work your way up.

Melanie Avalon: Yeah, I'm so glad you said that because we had had obviously a lot of questions about dosaging, like Jennifer said, "How much can or should I take?" Claudia said, "How much to take? What's the dosage?" Anna Maria, "When is the best time to take it to optimize results?" Amy, "Is it best to cycle it or take it every day? Should one take it at the same time every day or time it more specifically to be ingested before you eat a potentially glucose-spiking meal?" Cheryl wanted to know "Do you take it with food or on an empty stomach?" And Nydia wanted to know "Does it break the fast?" Teresa also wanted to know "Is it something that you can take daily? I know Shawn Wells listed as one of his most recommended supplements. But I've heard Cynthia Thurlow say that she has people cycle it. I will put a link in the show notes, by the way to an episode I had with Shawn Wells on the Melanie Avalon Biohacking Podcast. I adore Shawn and he is one of the go-to people in the supplement world, he's just a phenom when it comes to that, but yeah, to answer all of those questions, Scott just gave a really nice overview of the dosage and we thought long and hard about what dosage to do for it more. Again, going back to what we talked about in the beginning about the craziness with regulations. It's crazy how you have to like figure out what you can actually say on the label to get the dosage that you want. It's hard to describe. But basically, I had a very clear idea of what I wanted to say. And it had to go through Scott and like the legal team to get it on the label the way I wanted it.

Scott Emmens: That is correct. And I think, that's why we take those precautions because it's important for the public to make sure that what we're saying is in line with what is appropriate, but also to make sure that we're following all of the guidelines, guidance, and making sure that we are in compliance to that. That comes from 25 years of pharmaceutical lawyers pounding into me what I can't say. I want to make sure we do that, but on the other side, it's also what is it that we can say that will really make sure we're giving a clear specific guidance that is in the best alignment with what the data and the research suggest. And I think we got there and I think to your frustration, Melanie, I think a lot of people assume that the supplement world is a free cowboy world. But there are very stringent guidelines on labeling, claim that you make on that label, what you can say, what you can name it. And even down to like, the font size and how you list the ingredients and what size, certain ingredients have to be in the font size. I mean it gets very particular. So, again, going back to this, "What is GMP?" If you're following CFR 21, which is the regulations on how you label a supplement properly along with what this GMP mean, it's extensive and I think that's been one of the learning lessons that you have come across as well. How many things you have to do to make sure you've done it? But then again, how many other companies want to escape that edge that goes 75 and a 65 and make sure they don't get a ticket. And we'd rather go 65 and 65, then do the 75. And I think that is an interesting learning from a lot of people that we work with in this space, physicians [unintelligible [00:39:42] and so forth.

Melanie Avalon: Again, just another reason I've been grateful to work with you because you get all of this and I have learned so much, and it's just really been a really amazing incredible experience. So yeah, the dosage we landed on that we mentioned is based on the majority of the study. Probably the majority of the studies are 0.5 g or 500 mg, those are comfortable three times a day. But it ranges from, actually in the studies it's not normally on the lower end, but it can be, so I wanted it to have it, a minimum of like 500 mg up to 2 g, which seems to be the upper limit. That's the way we had it working on the bottle so that it could cover that range. I will say-- because we got a question because I had Megan Ramos on the Melanie Avalon Biohacking Podcast, she's amazing, definitely listen to that interview with her. She shared a negative experience she had with berberine experimenting with it during pregnancy, I think.

Scott Emmens: Yeah, that's a no, no.

Melanie Avalon: Yeah, and she was taking 2 g which again is the upper limit of that. For example, Lucy said, "Megan Ramos mentioned a few times that she was very sick with a negative reaction to berberine when she was on the Melanie Avalon Biohacking Podcast. I would like to know the main contraindications for berberine and how to avoid similar situations." Again, in that situation, revisiting that episode, Megan was taking the upper limit and while she was pregnant, I would start not at the upper limit, not take it during pregnancy or work with your doctor. So, definitely, you just want to be aware of all factors involved.

Scott Emmens: So, here are the contraindications, there're a few but they're fairly rare except for pregnancies. The first one is, if you're on Cyclosporin-A, you do not want to take berberine because it can have an interaction with the CYP43A for enzyme in the liver. Then you also do not want to take berberine with warfarin or thiopental, I think I'm saying that right, thiopental or tolbutamide because it can displace them from increasing the blood and increase the blood toxicity of those particular drugs. Warfarin has what's called the very narrow therapeutic index. Some of these other drugs do as well. If you increase just their bioavailability a tad or decrease it a tad it either will become toxic or can become ineffective. Those are contraindications. And then macrolide antibiotics such as azithromycin and clarithromycin may also interact, they're not contraindicated, but they are certainly something that you do not want to take berberine with unless you absolutely had to, based on a physician recommendation. And lastly, we do not want to take berberine if you are pregnant, that's contraindicated as well.

Melanie Avalon: Yes, I'm glad we could speak to that as far as does it break a fast? No, it will support your fast if anything. I actually don't take it the way most people take it. Well, first of all, I'm not eating three times a day. I'm not taking it three times a day before meals, I actually take it in the morning in the fasted state. And then I actually don't take it later before my meal. Although I probably should experiment with doing that come to think of it that would probably be beneficial. The reason I was doing that was I was just seeing the biggest spike in my blood sugar in the early part of the day, but you can really experiment and find what works for you. But typically, people are taking it before meals. Yeah, do you have any thoughts about that, Scott?

Scott Emmens: If you have a CGM, you want to experiment with that or if you take your blood sugar through another means, I think you want to experiment with that. For me, personally, I'm going to take one probably on an empty stomach starting when I start my new regime in January. Typically, when I take berberine, it's going to be about an hour to an hour and a half before my meal because I want to get the berberine inside my intestines, I want it to be metabolized and we're talking a little bit about the metabolites and the active metabolites of berberine. I think about an hour to an hour and a half prior to my meal to ensure that the maximum blood plasma level is there and that the metabolites are beginning to get into my system. That to me seems reasonable. Now, if you have GI upset, it's probably going to be the best to take it closer to your meal. I think you want to experiment with that both from a what's most comfortable for you? And then if you have the ability to measure your blood glucose, what's working best for you? For example, there's someone who owns a CGM company, he has a podcast. I've just listened to his podcast in preparation for the show and he had some limited success with berberine pre-meals. 

Now keep in mind, this is someone who is on a very restricted diet, he understands insulin, he's probably already in a low-insulin, low-glycemic state to begin with. He didn't see a lot of change with berberine before meals, but when he took it for the fasting insulin in the evening, he noticed dramatic decrease in his fasting insulin in the mornings. And that speaks to the liver part of gluconeogenesis because your liver's job with gluconeogenesis is to keep you from going into hypoglycemia while you sleep. And when you are diabetic or you have blood sugar issues that are beginning, your liver might be getting the wrong signal thinking, "Hey, we don't have enough glucose." So, it's pushing glucose out even though your glucose is already very high. So, based on the various ways that seems berberine works, I think each person's body type and where they're at, it's going to have a different impact, my personal recommendation for me is going to be to try to start taking it on an empty stomach, hour and a half before meals is what I currently do. And then I might experiment with a pre-evening dose.

Melanie Avalon: I'm so glad that you mentioned body fat. I know you're talking about it in a little bit different context. But I do want to talk briefly about the super cool effect that berberine can potentially have on body composition especially because I know a lot of people-- one of their main goals, possibly why they're listening to this podcast is for body composition effects. And there's been a lot of studies looking at berberine's effect on body re-composition with or without weight loss. So, it seems that in particular berberine can actually reduce the levels of inflammatory fat specifically, so visceral fat is a type of fat that is found surrounding the organs. And it's actually the type of fat linked to metabolic health issues compared to like subcutaneous fat, which is found underneath the skin and which is considered to actually be more benign when it comes to health issues. So, berberine has been found in some studies, it leads to weight loss specifically reducing visceral fat and in some studies, there's actually not weight loss, but there is a shift in the type of body fat, which is super cool. Basically, it's making your body more healthy when it comes to fat. Mice treated with berberine have actually been found to have shrunken adipocytes. Basically, their fat cells are smaller which is super cool. Other studies basically propose that the anti-obesity activity of berberine can involve in part not only decreased size of lipid droplets but actually also the number of lipid droplets. There's a study suggesting that berberine actually increases thermogenesis in brown and white tissue.

Scott Emmens: Yeah, that was very interesting to me.

Melanie Avalon: Yeah, basically increasing burning calories in your fat tissue, which is very cool, because you really want to stack especially with our modern diet environment, you want to do everything you can to stack the cards in your favor, to have a healthy metabolic profile when it comes to body fat. And it can be hard to do that, especially when there are cellular mechanisms involved. And anything that can really affect that, like berberine, can definitely be something to try. It can also discourage the creation of new fat cells "super cool." And that's actually by affecting transcripts and factors that are involved in creating fat cells in the first place. And then, for example, a review of five studies that encompassed 1078 women and you know I love when we got studies in women, found that it did indeed induce a redistribution of fat tissue, specifically reducing that inflammatory visceral fat that I spoke of. And speaking of the inflammatory potential, not only is it reducing the amount of inflammatory fat, it actually may make fat in general less inflammatory by reducing the recruitment of macrophages to fatty tissue. So, macrophages are basically-- for these things that go in-- and you can think of them like Pac-Man, they go and gobble up things. They're good, we want them in our bodies. They deal with getting rid of waste and fighting pathogens and things like that. But when you have an overabundance of them, it can be a very inflammatory state. And a lot of people's resistant fat, when people really just struggle to burn fat. It can be because the fat itself has become inflammatory, and it becomes resistant to fat burning.

Scott Emmens: Are you referring to brown fat versus white fat in adipose tissue?

Melanie Avalon: It found that it activated thermogenesis in both of them which is super cool. Did you find one showing that it increased brown?

Scott Emmens: Yes, I found a few studies that say that berberine promotes the recruitment and activation of brown adipose tissue in mice and in humans, which was pretty interesting. There was another study about berberine-activated thermogenesis in both white and brown adipose tissue, but one of the things I thought was so interesting was that it does seem it can help your body promote brown fat, thus thermogenesis and brown fat is packed with mitochondria. It keeps you from shivering, that's why babies have a lot of brown fat versus white fat, white fat that being the inflammatory version, brown fat being more of what they call an activated fat which has its own mitochondria in it and really actually is more of a positive energy-burning fat than white fat is. So, that I found really interesting. And even so to get to your point, if you don't lose weight, if you're just shifting that fat from the more inflammatory to the less inflammatory, more highly energetic fat, I think you're going to reap a lot of benefits.

Melanie Avalon: I'm so glad you said that, you really revealed that you haven't a grasp of what's going on because brown fat and white fat like Scott mentioned, brown fat is really high in mitochondria, it's activated by cold is something that activates it, it actually helps you lose weight which is ironic because it is fat, but it creates heat. And it basically wastes energy. But the thing that you said, Scott that I mean, I already knew this, but maybe made it aware that you actually really know what you're talking about. I think a lot of people think brown fat and because they associate it with cold, they think "Oh, that's like shivering," but it's not, it actually keeps you from shivering because the alternative to brown fat is to shiver, basically.

Scott Emmens: Exactly, and do you know how I know that, Melanie?

Melanie Avalon:  No.

Scott Emmens: Ice baths have taught me that. [laughs]

Melanie Avalon: I was going to say cryotherapy.

Scott Emmens: Yes, I am an ice bath guy. And I'm about to embark on a January 1 through February Polar Plunge for mental health benefits. I am currently back in training filling my tub up with giant hunks of ice and getting in there for 10 minutes or so to adapt. And I discovered the benefit of brown fat as I was really-- This goes back to 2016 when I first began doing ice bath, which by the way changed my life in so many ways. But that's when I discovered what brown fat was, why it was important and how I adapted to the cold over time by creating more of this brown fat. I mean, the first time I got in an ice bath, it was 60 seconds of pure shivering and agony. Three months later, I could sit in there for 8, 10 minutes at 40 degrees temperature of Fahrenheit and not shiver at all. In fact, one time I stayed in long because I hadn't shivered. I did get a little hypothermic, so that's how I learned about brown fat and white fat was through ice bath.

Melanie Avalon: Yeah, that's super cool. I remember Scott and I met. When did we meet? Spring of 2021?

Scott Emmens: I think you're right. I think it was April of 2021.

Melanie Avalon: Yeah, because we launched serrapeptase in 2021.

Scott Emmens: November. Yeah.

Melanie Avalon: Yeah, I think that was one of our first conversations way back in the day.

Scott Emmens: First conversation was ice bath and then followed by a lot of discussion on infrared, near-infrared and therapy and saunas, which I'm also a huge fan of, by the way.

Melanie Avalon: Yes, so many things. One last health benefit-related thing I think we should talk about, especially with this show one of the reasons people often do fasting, well, it's not the reason, but something we've talk about a lot with the benefits of fasting is how fasting stimulates something called an AMPK, which is basically a fuel sensing enzyme. It plays a key role in how our bodies use energy and it's activated by stressors like calorie restriction, fasting, and exercise. It is associated with so many health benefits like you want AMPK activation, it helps with longevity, metabolic health, inflammation, so many things. Berberine has found to be a very potent stimulator of AMPK, which is awesome. And then another fasting-related thing we talk all the time on here about autophagy which is activated by fasting as well. And it's where the body actually goes down and breaks down problematic proteins and recycles them. It's like a cleanse on the cellular level. It's very, very important for metabolic health and longevity. And berberine has also been found to be a stimulator of autophagy, so that is awesome.

Scott Emmens: People underestimate the importance of healthy autophagy getting rid of cells or what they might call zombie cells or mitochondria that need to go because they'll contaminate the other healthy mitochondria around it. I think autophagy is a tremendous benefit. And obviously, the AMPK there's a plethora of data on all the various things that impacts across your longevity and health span. One of the things that I don't think we touched on but, I know came up in literature quite a bit, is the positive benefits of berberine on the liver. And I'm a big guy on liver. I think if your liver is not functioning right, if it's not making bile, if it's not digesting your toxins properly, you're going to end up in trouble. And so, to me, I think that the liver benefits of berberine have probably underestimated at this point. There's not as much data and studies as I'd like to see. But there is definitely data to suggest that it works to support liver enzyme health, liver function in the presence of toxins, and I think that is really important. When you look at the overall effect of what berberine is doing to your point earlier, it's working on AMPK, it's working on glucose, it's working on your gut microbiome, it's working on your liver and your liver's function. And I think all of these things combined lead to, in my mind, one conclusion which is, there's something about this particular product that allows your body to function in an optimal level while keeping the blood glucose down, supporting mitochondria, supporting liver health and I think it all ties back to, if blood glucose and insulin are lower, then you're going to have a cascade of positive effects across your body. And I think that is why CGMs have become so popular as people realize that if they can keep their blood glucose at a reasonably modest normal level without having huge spikes throughout the day, that overall is going to lead to a longer and healthier lifespan. The data on that is pretty convincing. That's where I think berberine shines as this molecule plant alkaloid that just has so many benefits. So back to the liver, there is a couple of studies on liver enzymes and also on liver function. I would encourage people to take a look at that research. Again, of course, always speak to your doctor if you're taking anything for liver disease.

Melanie Avalon: I'm so glad you mentioned that as well because that actually goes really well with one other health benefit I want to touch on and it also involves the liver, so glad we're talking about it. And that is the role of berberine on cholesterol levels and lipid panels. Margaret said for example, "Is it okay to take it long term to help lower cholesterol" and we can speak to the long-term aspect in a bit but just as far as the cholesterol side of things. Not only does it directly reduces the absorption of lipids into circulation from your gut, because the whole caveat there is dietary cholesterol is not necessarily the primary driver of problematic cholesterol levels. It's more at least in my opinion, the creation of endogenous cholesterol and what's happening with that. And the effects in the liver on cholesterol and lipids is-- I mean, there's so many so.

It can promote the liver's LDL receptor mRNA expression to beneficially modulate LDL levels, it can directly inhibit the creation of cholesterol and triglycerides in liver cells. In rodent trials it's been found to inhibit NAFLD, nonalcoholic fatty liver disease in mice fed a high-fat diet, which is huge and in human trials have actually found that berberine supplementation can reduce liver enzymes in patients with type 2 diabetes and so going back to what Scott was saying about liver health and it can also reduce fatty acid synthesis directly in the liver and a lot of transcripts and factors related to fatty liver. And for example, there was one study in humans and not only did they find decreased body weight and BMI in those on berberine, but what was super cool about the study is it had people do berberine and then have a washout period where they were not taking the berberine and then go back on the berberine. And they found that their triglycerides, their cholesterol, their LDL, and their HDL all improved based on when they were like taking the berberine. When they were on the berberine, it improved. When they went off, it went away. And then when they went on again, it approved again. Lots of potential benefits there with cholesterol and lipids.

Scott Emmens: Yeah, I totally agree. And the one part I'd like to focus on that is with triglycerides. Having been in the diabetes universe for 15 years or so, one of the things that I spoke with when I worked with endocrinologists, those are the specialists that treat diabetes, the thing that the cutting-edge endocrinologist would tell you is if you see someone that has a relatively high fasting glucose, but they are not diabetic, but their triglycerides are above normal. He's like that person is going to have diabetes if they don't change their lifestyle in a few years. Triglycerides are the leading indicator like "Hey, you're on your way to diabetes if you don't change this." Your body is basically taking this sugar and trying to figure out what it's going to do with it because it can't do something. This isn't the scientific way to say this, but basically, your triglycerides are this canary in the coal mine, that if they're high, but your blood glucose hasn't quite broken, technically the diabetic limit, you're probably on your way there. That's something you really want to look out for [the fact that it does have these studies that show that it can have a positive impact and support the body's ability to reduce triglycerides really says something to me about the way that it's working for blood glucose.

Melanie Avalon: And I think that actually ties in nicely to something that I want to talk about, which is this specific form that we chose because we got a lot of questions about dihydroberberine. for example, Teresa said, "She wants to know the difference between berberine versus dihydroberberine." Erin said, the same thing, "What's the difference between those two?" Suzie said, "What is the difference between them and what is the best?" Paul said that "He actually did better taking dihydroberberine that he didn't have the bloatation and the gassy issues?" And then Amanda said that --Oh, this is something that we can speak to the absorption levels. Amanda said, "Mike Mutzel talks about not using the highly absorbable kind," which presumably, I'm assuming is the dihydroberberine, as that's how berberine is effective in the gut by not being highly absorbable. Just speaking to what you were just talking about Scott with all of these over-encompassing effects and many things that are going on, shall we talk about? Because we debated for a long time about? Well, more so in the beginning, I think once we got to an understanding about it, we felt pretty good. But we were looking at? Should we do a berberine or should we do a dihydroberberine? Dihydroberberine is a newer form of berberine, at least from being like sold and marketed, which is said to be more absorbable and said to have a more potent effect on lowering blood sugar? We chose not to do that. Scott, would you like to explain a little bit why?

Scott Emmens: At first, it was two things. I think this goes back to my experience with prodrugs and metabolites prodrugs and then also looking at the data. Of the 30 years' worth of research that we have a good grasp on and there's a ton in the last 15 years, all of it is on berberine or the vast, vast majority I should say. There is very little data on dihydroberberine beyond just either its increase of "plasma level," but plasma level is not really what separates Berberine from the pack. I'll give you an analogy and tell me if it's apt Melanie. But with CBD, for example, "If you get a pure 100% isolated CBD, you may have no effect from it because it's not just the CBD, it's the CBD, CBG, it's the other cannabinoids inside that product that give it an entourage effect along with terpenes and other things that create that. Then if you add the other factor into metabolites from a prodrug is a drug that goes in as an inactive substance. And then your liver converts it into an active substance. Well, berberine happens to have no less than four active metabolites and as many, in some reports as 17 metabolites. And we don't know what those metabolites do, but it's pretty clear, and here's a direct quote from an article. Let me just make sure I get the title. "This is the metabolism of berberine and its contribution to the pharmacological effects." 

And then let me read this quote because this wasn't something we had focused on a ton in the beginning, but we discussed it, but the more we did the research, the more evident it became that there's something unique about it. "Even though berberine possesses a low oral bioavailability, it has exhibited marked biological activities in vivo which is in people and concentrations of its major metabolites such as berberrubine, thalifendine, I'm going to say these wrong, I'll butcher these names, demethyleneberberine, and jatrorrhizine, that is butcher of those names, but they are relatively high. And then it says, "These reports indicate that the metabolites of berberine may be active constituents which are representative of the biological activities of berberine in vivo and I mean that sums it up that there is something unique about berberine despite this, "Low bioavailability." Study after study shows that it works and then now we're getting more and more studies that are coming in. And our ability to measure these metabolites that are coming in active tablets, meaning your livers convert it into a new active form of berberine. They are actually also stored in your various organs, like your liver, in your kidneys, in your brain and other places that allow for these other properties of berberine or that we suspect based on the data allow for these other properties of berberine. By isolating one particular compound, yes, you may get less side effects, but you may not get all of the benefits of berberine. And I think between that and the fact that the data is very consistent on berberine, says berberine is the way to go. Now, we might decide to do a dihydroberberine in the future for some other specific reason, but if we're looking to get the maximum benefit across the spectrum of berberine, then we wanted to use the whole berberine plant.

Melanie Avalon: I think it's so interesting, Scott found, I don't know if it's the one that you were just speaking about, or if it was a different one. But you found this really great article, which basically speaks to this issue that people will say about berberine, which I find really ironic because people will say it's not very absorbable, like an issue basically, and that we need to fix it. But it's just really ironic, because all of the studies for so long and then it's been used for thousands of years, have been working with it in this form, so clearly, it's working in this form.

Scott Emmens: And then all of the data is in this form. When they saw the studies we read to you today, all of the data we've read to you today is from berberine. And so, you could take a chance that yes because it's more "Absorbable" and less impactful in your gut. Well, okay, maybe that works, maybe that doesn't just because it's higher in your plasma doesn't mean that it's high or concentrated in your organs, which may be the very benefit we're getting. I think you're right, it is ironic that we think we have to fix a product.

Melanie Avalon: It's pretentious.

Scott Emmens: Yeah, we have to fix a product or a natural alkaloid that has decades, in fact, let's go back to your earlier number of 4500 years of use. So yeah, I'm pretty confident berberine is the way to go. And for those folks that do have jabs and again, I would say, take it closer with your meal at first, start low and go slow. So, try one, just take one a day for a while, get your body used to it. You had mentioned maybe it's a detoxification process, go low and start slow. But yeah, I think you're exactly right. To say that this other form is better with no real data, I don't think is the right way to go. Is dihydroberberine, does it have some advantages? It very well could. But when we're talking about all of the data, and all of the studies, and these active metabolites, this is the product that I feel most comfortable taking.

Melanie Avalon: I think that's the key thing to focus on, which I'm not saying at all, that creating an isolated form of anything might have more of a benefit for maybe a certain goal in mind, like you might be able to finesse it to, have a specific intended effect. And maybe with dihydroberberine, maybe people, but again I would just need to see more literature and experience with people. But maybe it does work better for some people, which is great. But what's interesting is often rather than saying-- when people pause at dihydroberberine, for example, often rather than saying, this is another form of berberine that may be more beneficial for certain people for certain goals. It's positive, like berberine isn't very absorbable, they are like discard. They discard the entirety of the berberine literature, which makes no sense. And we do this with other things. We do this with turmeric and curcumin. People will say that we need to take our curcumin supplement because it's not very bioavailable in turmeric, when people have been using turmeric for the benefits for so long, people do it with resveratrol and wine. It's a very common thing that people do.

Scott Emmens: Or like a polyphenol versus an individual phenol. And that's why I love this one specific sentence, which is even though berberine possesses a relatively low oral bioavailability, it has exhibited marked biological activity in vivo. And the concentrations of its metabolites such as I butchered those, indicate the metabolites have an active constituent that represents significant biological activities of berberine. And in fact, berberine studies have revealed metabolites have shown similar bioactivity and it goes on and on. And there is something unique about it, the way that it is absorbed is not directly correlated to plasma. And in fact, it might be within this article or the other one that I had sent you, it says that, "Part of the reason that the plasma levels in berberine aren't high is because it's getting pushed into the organs where it needs to be and that was mind-blowing to me.

Melanie Avalon: Hi, friends, I'm about to tell you how you can get my favorite electrolytes for free. Yes, completely free. And a very exciting limited-time announcement. LMNTs chocolate medley is here and you better hurry because last year's LMNTs holiday electrolytes sold out in less than a week. LMNTs chocolate medley includes three flavors, the brand-new chocolate caramel, mint chocolate, which is a fan favorite from last holiday season, and chocolate salt. The flavor that taught us electrolytes can be the primary element of your favorite hot beverage. Friends, do not miss this. The chocolate medley is here just for a limited time and when it's gone, it's gone. So, stock up now. In fact, I'm really hoping it's still here by the time this runs and why do we want electrolytes? If you've been having issues with intermittent fasting, electrolytes may just be the thing that you need and/or have you heard of something called the keto flu? Here's the thing. Keto flu is not actually a condition. Keto flu just refers to a bundle of symptoms, headaches, fatigue, muscle cramps, and insomnia that people experience in the early stages of keto dieting. Here's what's going on. When you eat a low-carb diet, your insulin levels drop. Low insulin in turn lowers the production of the hormone aldosterone. Now, aldosterone is made in the kidneys and it helps you retain sodium. So, low aldosterone on a keto diet makes you lose sodium at a rapid rate. Even if you are consciously consuming electrolytes, you might not be getting enough. In particular, you need electrolytes, especially sodium and potassium in order for nerve impulses to properly fire. Electrolytes can easily be depleted while intermittent fasting.

Robb Wolf, who as you guys know is my hero in the holistic health world, worked with the guys at Ketogains to get the exact formulation for electrolyte supplements to formulate LMNT Recharge, so you can maintain ketosis and feel your best. LMNT Recharge has no sugar, no coloring, no artificial ingredients, no junk. They're used by three Navy SEALs teams, they are the official hydration partner to Team USA weightlifting, they're used by multiple NFL teams, and so much more. We have an incredible offer just for our listeners. You can get a free LMNT sample pack that includes all eight flavors. Citrus, watermelon, orange, raspberry, mango chili, lemon, habanero, chocolate, and raw unflavored, and the raw unflavored by the way is clean fast friendly, You can try them all completely free when you make a purchase at our link drinklmnt.com/ifpodcast. You can get this offer as a first time and as returning LMNT customer. I know there are a lot of returning LMNT customers. The feedback I hear from you guys, "Loving LMNT" is amazing. LMNT offers no questions asked about refunds on all orders. You won't even have to send it back. And this offer is exclusively available only through VIP LMNT partners. You won't find this offer publicly anywhere else. So, again, the link is drinklmnt.com/ifpodcast. And of course, you better hurry if you want to get LMNT's limited-time holiday chocolate medley and we'll put all this information in the show notes. All right now back to the show.

Also related to our whole creation process. We had that question at the beginning about dihydroberberine versus berberine. And then when we decided on berberine, it was time to actually create it and Scott. Shall we tell listeners a little bit about our journey? [chuckles] 

Scott Emmens: Journey is a good way to put it, [chuckles] would you like me to start?

Melanie Avalon: Sure.

Scott Emmens: So, breaking the fourth wall a little bit, Melanie had some very specific criteria, as usual, all legitimate. And we began this pursuit for the perfect berberine. And one of the berberines that we looked at that had this really great story in this great, it's organic from the Himalayan Mountains. And then there was another one from the western part of the country, yada-yada, handpicked, etc. However, when we tested those berberines, they came back with both impurities and their potency level was remarkably low. And then I did a little more research and found that these companies also had some FDA warnings. There's a thing in the FDA when you have a GMP-certified facility, it's not just about the source of where you get the product. The most important thing is, have you done the four critical components of testing, which is strength, identity, purity, and compliance composition? And what we do at MD Logic Health and this is why I think we are so selective about who we partner with in terms of suppliers and also co-branding partners such as Melanie is, we want to be the best of the best, just like Melanie. What we discovered was that these other berberines not only failed to meet the specifications that were required but that also did not meet GMP, meaning the facilities themselves had multiple 43 notices or 402 requirements, which basically means that they were citation with significant issues in terms of their facilities GMP. Some folks, well where's it sourced from?

Well, that's important except the most important thing is have you done the correct analysis to protect yourself against heavy metals, purity, identity, strength, toxins, etc. And when we get a product, in this case, berberine, we quarantine everything that comes into our facility. It has been tested before it is allowed to come in for those four things back to what is the identity? What is the strength? Or the amount of active ingredients? What is purity? Meaning, are there toxic metals? Does it meet all of the standards that we're referring to? And is it meeting all of the compliant FDA requirements for purity, potency, etc. Those four things are done before that product even comes into our doors. Unfortunately, two of those products failed to meet our standards, which obviously disappointed us, but we were not going to allow faulty product or subpar product into the process. And when I went to look back at the companies that were utilizing these products, what I discovered is they had multiple 43s including but not limited to various toxins, lack of doing the standard studies, and in shocking fashion rat feces in a number of their herbs.

Melanie Avalon: Was it in the herbs or in the facility?

Scott Emmens: It was in the facility. I don't know whether it was in the herb or whether it was contaminated in the facility, or how but it was tested and found in the facility, meaning that multiple of their herbs had rat feces in them. And this is a pretty well-known brand, which we're not going to mention. But the fact of the matter is that they had obviously either not quarantined it and brought it in with the feces or the feces was in the facility and they hadn't done their due diligence on making sure that the facility was properly protected against those types of things. When a company says they're GMP certified that's one thing. But they need to be following all of those GMP tests. The reason that we quarantine the product before we bring it in, is if that product is contaminated you run the risk of contaminating your entire line. That's why it is quarantined and tested prior to its entry into our facility. 

Once it's tested and it passes all of those tests, we then bring it into the facility and then we do again, what's called batch testing. And we retest that same product after it's been manufactured to make sure it still meets all those specifications and has the amount of milligrams we'd say it has, it has the proper ingredients, and it still meets all of the same parameters to make sure that it didn't get infected or contaminated along the way. it's not just important to do it after you've created it, it's important to do it before it enters the facility. It's important to make sure you follow all of the criteria that GMP lays out in terms of where you store your product, how high you store it, what temperature you store it at, all of these things add up to what's called good manufacturing process. It's more than just testing for purity, strength, identity, and compliance. It's also, "Did you do the proper testing on how long it's going to last on the shelf, for example? What temperature did you expose it to? Did you have a CoA from the supplier of the ingredient and then did you also subsequently test it?" Some people will take the CoA from the supplier as the gold standard and then not do their own testing. That's not the way to go, because they may have gotten one sample to pass that test. But they can give you a different version or a different sample or a different supplier. And sometimes companies will change suppliers without then doing a retest of the ingredient. And then of course is not kosher either. You've got to make sure that you're doing GMP, the way GMP is written. And that is why there's a difference between us and folks that aren't following those same procedures.

Melanie Avalon: Yeah, so I actually just pulled up the warning letter that you had found about that company because I wanted to see exactly what it had said. And this wasn't for their actual berberine, it was for the company in general but their manufacturing plant basically. And for example, this is direct from the FDA warning letter. It says, "Tree nut shells, peanut shell, corn, rodent feces, and seed foreign material were detected in their ashwagandha." "Tree nut shells, glass, hard plastic, and rodent feces were detected in their bilberry fruit." And there are a lot of other things as well. Scott, this is so shocking, so like ashwagandha that they're talking about, they had rodent feces in it as well as all of these allergens. If you go to their Amazon page, there ashwagandha has 506 ratings, 4.5 stars, it says that it's organic, it says it's free from gluten, dairy, and soy. The other pieces in this warning letter say that they found wheat in some of their other-- "Wait, wait, wait, sorry, I missed that." Wheat and rock were also found in their ashwagandha. So, "Ah", listeners, literally, so like you can go to Amazon and get this ashwagandha 506 ratings, 4.5 stars, it says "It's organic," it says "It's gluten, dairy and soy free." And when they tested this, when the FDA tested this, they found gluten, rat feces, and a myriad of other things. This is just so problematic. This is so problematic.

Scott Emmens: It is. I want to make the statement that I think this is the more rare companies, but it does happen, it does exist that you can have a GMP facility with great ratings and a decent brand name and still have-- I mean, I think those are pretty significant issues.

Melanie Avalon: And this isn't like some small-- like they have a lot of reviews on Amazon and a lot of products.

Scott Emmens: Correct? So, bigger doesn't mean better. What means better is, "Did you follow GMP and what is your track record with the FDA?" And we have an immaculate track record. And I think that speaks volumes. But the reason we have it is we just believe in following the procedure to make sure that like our families take our products, I take AvalonX products, I take MD Logic products, I give my family MD Logic products, I would never want to have skipped a process or a step. Because those processes are put in place for very good reasons. And most people aren't aware of those because they're not readily public-- it's not readily public information. But I think I remember I got a five shock emoji face from you when I sent you that link.

Melanie Avalon: Listeners, friends, do your due diligence when you choose the supplements that you choose to put in your body. We found a source that we felt really good about with the testing and we tested it for purity and potency. But then we wanted to go one step further because this was my first supplement that was an herb. My previous supplements have been serrapeptase and magnesium. We had the certification from the source that it was free of pesticides. But it was really, really important to me that we do third-party testing on that, just like we did the third-party testing for the purity and the potency because again it's an herb, it's being grown. That took a while because it took a while to find, what was the word like a company that would do the test?

Scott Emmens: It was a third-party laboratory that would do pesticide testing as well as other testing. But we chose at that point, we had all the other testing, we had done internal heavy metal testing twice, internal purity, internal identification and compliance, so at that point we really just wanted to make sure is this was pesticide-free by all the definitions that are set by the US Government and then some. And we set that out for a third-party pesticide test.

Melanie Avalon: Yes, and I'm so happy we found a company that we really like to do that and it came back all clean, all good. And I should tell them the nuance of it. Another reason it took so long to find a company is most of the companies would just give you a blanket, like a yes/no about whether or not it was below a certain level. But I wanted it to be quantified. [chuckles] I wanted to know if it was there, like how much was it there? It took a while to find a company that could work with us to do that, but we did. And we got the green light, it's all good, no pesticides.

Scott Emmens: It really is. And I'll tell you, I would not take any other berberine than this one based on the fact that we know the source is good. We've triple-tested it in-house for the four cores, which is purity, heavy metals, etc., identity, purity, strength, and potency. So, at this point, we feel like we've got a great berberine that's pesticide free, heavy metal free, toxin free, mold free at the right dosage, and in a glass bottle and on top of that with no stearates, palmitates, or other heavy chemical anticaking or filling agents. It's the purest best berberine I think that you're going to find in terms of literal testing and its final ingredients.

Melanie Avalon: I always have to ask you Scott, its filler and lubrication agent?

Scott Emmens: Yes. there are two things that people should be familiar with it. There's what they call lubrication or anticaking. Because when you put these products through these machines to put them in little tiny capsules, it requires some lubrication agent. And that's typically a magnesium stearate, silicon dioxide, or they'll call it silicon, which is silicon dioxide because that FDA allows you to say silicon versus silicon dioxide, little euphemism or a calcium palmitate. I'm okay, I take products with magnesium stearate. I don't think it's the end of the world. But if you're taking 15 capsules a day, you want to get it as pure as possible. And I think in this day and age, we're already exposed to so many things, we want to make sure that it's as clean as it can be. So yes, this product is free of magnesium stearates, that is an anti-caking agent which means it prevents it from blocking up the machines, which is also why we have to do small batches and why it's a little pricier because in order to shut down an entire line or have a dedicated line that has no lubricant or non-magnesium stearate/palmitate lubricant, you've got to have these smaller batches or a dedicated machine. And that's anti-caking. They're called lubricants and then there're fillers which are typically rice or cellulose or something else that you may or may not want. So typically, when we do a filler and we only do that when we have to whether that's an AvalonX product or MD Logic product, we use most benign possible filler there is which is methylcellulose, organic grown, human use, basically methylcellulose, which is like tree bark or fiber. And the only reason you do it is that the capsule doesn't shake loose. In other words, if the capsule size is-- you've got to get the capsule full, otherwise it's going to shake loose and the capsule doesn't feel right or fit right.

The anti-caking agents prevent the product from blocking up the machine, clogging up the machine, and keeping the product flowing into the capsules properly. But a lot of folks don't want magnesium stearate, hence why we go the extra mile to do two things which is A, use either no anti-caking or a natural anti-caking agent that is either beneficial for you or neutral or none. And then on the filler, we use either no filler or we use a filler that is methylcellulose or something super benign or beneficial rather than things like rice flour or other things that people can be allergic to.

Melanie Avalon: Yeah, so the berberine containing a very small amount of monolaurin, which is exciting because people will actually take monolaurin for its health benefits. But I don't like to emphasize it because it's not like-- it's barely in there. But yeah, so it's nice to have something that could be potentially beneficial in there as well.

Scott Emmens: And the monolaurin, in this case, would be the anti-caking agent. But to your point, some people take monolaurin as an actual supplement for health, for digestive health. And I think it pairs really well with berberine as I take it for digestive health in terms of its benefits.

Melanie Avalon: Yes. But I really want to emphasize, it's not like monolaurin is in there as a supplement like you're barely getting it. It's more just to point out that it's benign, like it's nontoxic.

Scott Emmens: Exactly, you're talking about a minuscule amount of monolaurin, so it's [unintelligible [01:28:27] supplementation of it. It's really just because this is either beneficial or neutral versus some people who feel that the stearates can be negative.

Melanie Avalon: Exactly, so yeah, I'm so excited because it's almost here. No, no, no, no when this releases it will have just launched. So friends, if you want to get this berberine we are having an amazing launch special that is through the holidays, through December 31 right like through the--

Scott Emmens: Correct, it starts on December 16 and goes all the way through the holidays through December 31. Perfect time for your January 1st New Year's resolutions and there's a tremendous discount that Melanie will have on her website. So, Melanie, I'll let you take it from there.

Melanie Avalon: During this launch special, you can get 15% off of one bottle or 25% which is amazing, off of two or more bottles. And that is just during the special and/or while supplies last. Stock up now. That we'll be at avalonx.us. Again, avalonx.us, 15% off of one bottle, 25% off of two or more bottles through the end of 2022. Beyond that, some other resources, if you want to stock up or get my other supplements, serrapeptase and magnesium, you can use the coupon code MELANIEAVALON that will get you 10% off or if you would like 20% off code, you can text AVALONX, just the word AVALONX, you will not believe how many people text, not AVALONX. They text like, they're like, "Hi, give me the 20% off code?" Like no, no, no that's not how this works, the computer can only read AVALONX.

Scott Emmens: It's a computer. Yes.

Melanie Avalon: It's a computer. So, text AVALONX To 877-861-8318 that will sign you up for text updates and will give you a 20% off code. You can also get email updates at avalonx.us/emaillist. And then both that 20% off code and the 10% off code MELANIEAVALON are also good at MD Logic Health, Scott's main company, they have an array of-- how many products do you have, Scott?

Scott Emmens: Right now, we have about 40-something skews and products. And we are probably going to have somewhere closer to 65 mid 2023, we got a very aggressive pipeline of either cutting-edge and/or newly formed versions of products that we feel like it would be beneficial.

Melanie Avalon: Yes, so that's super, super exciting. So, definitely check them out. I know one of the supplements we've talked about a lot on this show is your melatonin. I know people are really liking that one.

Scott Emmens: Fanfare for sure.

Melanie Avalon: Yeah, as well as Scott's collagen.

Scott Emmens: Thanks for mentioning both. The melatonin we reformulated by the way which is the exact same melatonin formulation, but we took out the rice and we took out-- I think it had a little mag stearate, so we removed that. So now that is an even more pure, more clean version of our Melatonin Max. And yes, our Marine Collagen is doing really well. People love it because you are getting 13 g of collagen plus you are getting what they call co-factors to create collagen or collagen synthesis in your body. People underestimate that part because you can take as much collagen as you want without vitamin C, manganese, zinc, vitamin A, and vitamin C. You cannot convert those amino acids into collagens. So, you can drink collagen all day, sort of making a cake with a ton of powder, but if you don’t use a little bit of sugar and butter, you are just going to have a giant flour cake.

Melanie Avalon: Yes, so I can guarantee you this collagen was Scott's baby, kind of like the way I am with my supplements. If you are looking for collagen supplement. This is the one that you want for sure. If you want to go through my site to get that, the link is melanieavalon.com/mdlogic and again the coupon code MELANIEAVALON will get you 10% off sitewide. As well as that 20% off coupon code that you by texting AVALONX To 877-861-8318. And again, stock up on berberine before the special ends.

Scott Emmens: Well Melanie, I've never been so excited for one of your launches as I am for berberine. I feel like your audience is going to love this. I feel like this is going to be a tremendous product for your fan base but most importantly, I think now having done three products with you and having had multiple discussions on your future products I feel like I need to assure your fans that you do not let a single thing go. Every single thing that goes into this product and does not go into this product. You have your eyes on, the research on, and I think together we are making a fantastic team and even more importantly great products that are really healthy and great for people and I couldn’t be more thrilled to launch berberine with you, so this is fantastic.

Melanie Avalon: I am just so thrilled and honored and excited and grateful as well. Listeners, working with Scott has been the dream partnership and I am just so grateful that I can finally do exactly what I wanted to do with the supplements and make them for myself and for everybody else, so I am so happy. Actually, this is a good way to end literally just right now Scott, you know how you were mentioning earlier the person at the CGM company who was sharing his experience on the podcast. He actually literally just emailed me because I had emailed him to tell him I was making a berberine. Would you like to hear what he said about berberine?

Scott Emmens: I would love to hear what he said. This is like serendipity.

Melanie Avalon: I know this is like in real life like real-time. [chuckles]

Scott Emmens: It's real-time and it's happening at the moment.

Melanie Avalon: Complete third party. All I did was I told him I was making a berberine supplement. So, he said, "Berberine is a great idea of all the supplements I've tested for glucose regulation, berberine has had the most significant impact and our internal staff experiments confirmed my anecdotal observations." One cool thing to test with berberine would be proper dosing. Most use berberine as a pre-prandial taking 500 to 1000 mg 20 minutes before meals. I tried that and it didn’t work for me." That's what he was saying, Scott. "A smaller camp including myself takes 500 mg twice daily morning and evening. While it did take a few weeks to see results, I saw an overall decrease in my own fasting glucose on that regimen." So that's a nice little testimonial and I think it really speaks to when you guys get your berberine you are going to need to find the way it works for you specifically.

Scott Emmens: That is a great way to end. I think that's serendipity.

Melanie Avalon: I think so. Well, this has been absolutely amazing and Scott you are going to have to come back for all of our future product launches. I hope you are down with that.

Scott Emmens: I can't wait. I look forward to any questions, comments from the fans. I'm starting to feel like a fan and a welcome member of the family of the IF Podcast. So, thank you so much for having me again, Melanie, I look forward to us speaking again.

Melanie Avalon: You too and this will have already happened, but have a Happy Thanksgiving.

Scott Emmens: That's right, you too.

Melanie Avalon: Bye.

Scott Emmens: Bye, bye.

Melanie Avalon: Thank you so much for listening to The Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice, and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team, administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and re-composed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Dec 11

Episode 295: Food Choices, Macros, Ketosis, Chronic Pain, Oxalates, Organ Meat, Variety In Fasting, Exercise, And More!

Intermittent Fasting


Welcome to Episode 295 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

BUTCHERBOX: Grass-Fed Beef, Organic Chicken, Heritage Pork, Wild-Caught Seafood: Nutrient-Rich, Raised Sustainably The Way Nature Intended, And Shipped Straight To Your Door! For A Limited Time Go To Butcherbox.com/ifpodcast And Get Free Ground Beef For LIFE Plus $20 off your first box!!

BEAUTY AND THE BROTH: Support Your Health With Delicious USDA Organic Beauty & The Broth Bone Broth! It's Shelf Stable With No Preservatives, And No Salt Added. Choose Grass Fed, Grass Finished Beef, Or Free Range, Antibiotic And Hormone-Free Chicken, or Their NEW Organic Vegan Mushroom Broth Concentrate! The Concentrated Packets Are 8x Stronger Than Any Cup Of Broth: Simply Reconstitute With 8 Ounces Of Hot Water. They’re Convenient To Take Anywhere On The Go, Especially Travel! Go To melanieavalon.com/broth To Get 15% Off Any Order With The Code MelanieAvalon!

FEALS: Feals makes CBD oil which satisfies ALL of Melanie's stringent criteria: it's premium, full spectrum, organic, tested, pure CBD in MCT oil! It's delivered directly to your doorstep. CBD supports the body's natural cannabinoid system, and can address an array of issues, from sleep to stress to chronic pain, and more! Go To feals.com/ifpodcast To Become A Member And Get 50% Off Your First Order, With Free Shipping!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get Free Ground Beef For LIFE Plus $20 Off Your First Box!!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz

Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

Go To cynthiathurlow.com/creatine and use code CYNTHIA for 10% off!

Episode 292: Creatine, Brain Health, Sex Hormones, Muscle Building, Insulin Sensitivity, Sarcopenia, Andropause, Mood, Motivation, BDNF, And More!

BEAUTY AND THE BROTH: Go To melanieavalon.com/broth To Get 15% Off Any Order With The Code MelanieAvalon!

Listener Q&A: Heather - IF

Listener Q&A: Robyn - Chronic Pain Flair

The Melanie Avalon Biohacking Podcast Episode #104 - Sally Norton (Oxalates)

The Melanie Avalon Biohacking Podcast Episode #153 - Bill Schindler

Ep. 238 Eat Like A Human: What Should We Eat? with Dr. Bill Schindler

Go to eatpluck.com an use the code CYNTHIA15 for 15% off!

FOOD SENSE GUIDEGet Melanie's App To Tackle Your Food Sensitivities! Food Sense Includes A Searchable Catalogue Of 300+ Foods, Revealing Their Gluten, FODMAP, Lectin, Histamine, Amine, Glutamate, Oxalate, Salicylate, Sulfite, And Thiol Status. Food Sense Also Includes Compound Overviews, Reactions To Look For, Lists Of Foods High And Low In Them, The Ability To Create Your Own Personal Lists, And More!

Go to safecatch.com and use the coupon code for MELANIEAVALON for 20% off!

The Science, Nutrition, And Health Implications Of Conventional Vs. Sustainable, Grass-fed, Pastured, And Wild Meat And Seafood, Featuring My Honest Butcher Box Review!

FEALS: Go To feals.com/ifpodcast To Become A Member And Get 50% Off Your First Order, With Free Shipping!

Listener Q&A: Therese - Repetitive Routines Or Mix It Up?

Listener Q&A: James - Constantly Changing Fasting Windows

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 295 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: A 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time and get ready for The Intermittent Fasting Podcast.

Hi friends, I'm about to tell you how you can get free grass-fed, grass-finished beef for life plus $20 off, yes free grass-fed grass-finished ground beef for life plus $20 off. We are so, so honored to be sponsored by ButcherBox. They make it so, so easy to get high-quality humanely raised meat that you can trust. They deliver 100% grass-fed, grass-finished beef, free-range organic chicken, heritage-breed pork, that's really hard to find, by the way, and wild-caught sustainable and responsible seafood shipped directly to your door. When you become a member, you're joining a community focused on doing what's better for everyone. That includes caring about the lives of animals, the livelihoods of farmers, treating our planet with respect, and enjoying deliciously better meals together. There is a lot of confusion out there when it comes to transparency regarding raising practices, what is actually in our food, how animals are being treated. I did so much research on ButcherBox. You can actually check out my blog post all about it at melanieavalon.com/butcherbox. But I am so grateful for all of the information that I learned about their company. All of their beef is 100% grass-fed and grass-finished that's really hard to find and they work personally with all the farmers to truly support the regenerative agriculture system. I also did an interview with Robb Wolf on my show, The Melanie Avalon Biohacking Podcast, all about the massive importance of supporting regenerative agriculture for the sustainability of not only ourselves but the planet. This is so important to me. I'll put a link to that in the show notes. 

If you recently saw a documentary on Netflix called Seaspiracy, you might be a little bit nervous about eating seafood. Now, I understand why ButcherBox makes it so, so clear and important about how they work with the seafood industry. Everything is checked for transparency, for quality, and for sustainable raising practices you want their seafood. The value is incredible, the average cost is actually less than $6 per meal, and it's so easy. Everything ships directly to your door. I am a huge steak lover. Every time I go to restaurant, I usually order steak. Oh, my goodness, the ButcherBox steaks are amazing. I remember the first time I had one and I just thought, “This is honestly one of the best steaks I've ever had in my entire life.” On top of that, did you know that the fatty acid profile of grass-fed, grass-finished steaks is much healthier for you than conventional steaks? And their bacon, for example, is from pastured pork, and sugar and nitrate free. How hard is that to find? And ButcherBox has an incredible deal for our audience. For limited time, you can get free grass-fed grass-finished ground beef for life in every box of your subscription plus $20 off, yes, new members can get free grass-fed grass-finished ground beef for life plus $20 off when you go to butcherbox.com/ifpodcast, that's butcherbox.com/ifpodcast for free grass-fed grass-finished ground beef for life plus $20 off and we'll put all this information in the show notes.

And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting, it's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things, like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup may be playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That's because ladies when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years.

Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means, when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so, you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life. And their makeup is amazing. Check out my Instagram to see what it looks like. Tina Fey, even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list, so definitely check it out. You can join me in my Facebook group Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well.

And lastly, if you're thinking of making Clean Beauty and Safe Skincare a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now back to the show.

Hi everybody and welcome. This is episode number 295 of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hey, Melanie, how are you?

Melanie Avalon: I'm okay as you know. I honestly forgot what this is like to be super sleep deprived because I put a lot of effort into making sure that I get a lot of sleep, like I prioritize it like none other. So right now, I'm currently in the virtual queue for the Taylor Swift Presale Concert. And it's been five hours and I'm like not present. And I was texting Cynthia being like, I don't know if I'm going to be able to record but we are here. But I forgot what this feels like, I took some coffee.

Cynthia Thurlow: Good. So, a stimulant will definitely help you, but you're like a real person.

Melanie Avalon: I know. But I feel like I'm not quite present.

Cynthia Thurlow: Yes, but it's amazing how when you have like one blip in your sleep radar, you actually you'll be fine. You'll be tired, you'll go to bed probably around your normal time and then tomorrow you'll wake up and feel totally normal.

Melanie Avalon: So true, I don't normally-- I think we've talked about this. How much coffee do you drink? 

Cynthia Thurlow: Zero.

Melanie Avalon: Oh, none.

Cynthia Thurlow: Yeah, I'm not a coffee drinker. And it's funny because I had some genetic testing done and they actually said I do fine with, caffeine but I have to be completely transparent and say I made it through all my pre-med classes, all of undergrad and grad school never drinking coffee.

Melanie Avalon: With no coffee?

Cynthia Thurlow: No coffee. And the nights, I worked nights in ERs and worked overnights in the hospital and no coffee. I would drink, I can't limit this. I used to drink Diet Pepsi, which is disgusting.

Melanie Avalon: So, you weren't getting caffeine?

Cynthia Thurlow: But I couldn't tolerate it, it's not something I could drink every day. It was like, I would bring it with me in case I felt like I literally could not keep my eyes open but not every day. So, I'm officially very much an early bird that is uncaffeinated, except for my occasional green tea, which I don't necessarily have every day out of laziness.

Melanie Avalon: I was thinking about it actually a few days ago. Because normally I think I've shared this before I literally just have like a sip of coffee, like a sip every morning. It's more just a mental thing. It's probably like no caffeine in it at all. But I was reflecting their day on how nice it kind of is to not be dependent on coffee because I know and I mean I would go through, like in college really intense periods and coffee is something were-- like I did my experiment with alcohol and wine where I didn't drink for a year to see if I was like happier not drinking and I realized I was much happier having wine every night. Like with coffee, I feel like if I go into a coffee every day, I think I am happier without coffee, because it's just nice not to have to use it. And then when you need it, like right now, it's like very potent, and I probably just had like, a quarter of a cup and I'm like, okay.

Cynthia Thurlow: [laughs] But I think it's also recognizing that this is like a good indication of a day that you do well with it. Like, I will take adaptogenic herbs or I will take glandular products if I feel like I definitely need a little bit of support. But I don't, I like the way coffee smells. I just don't like the way it tastes, I never have and it's ironic that I have a child that's kind of an espresso Americano snob and really is into his coffee and then the other three of us don't drink it at all.

Melanie Avalon: Oh, wow. Yeah. I will say though my thoughts on coffee just in case people are curious because I'm not trying to scare people away from coffee. I feel like the studies are pretty consistent that coffee drinkers have health benefits.

Cynthia Thurlow: Well absolutely, the polyphenols and the plant-based compounds in coffee and bitter teas are, it's undeniable. I think that's how I actually started forcing myself to drink green tea a couple of days a week with a understanding that those bitter plant-based compounds actually have physiologic benefits. And so, I'm like, "Okay, you're going to learn how to drink this?" And so, I iced my green tea. That's how I drink it.

Melanie Avalon: It's also pretty mind blowing. I'm pretty sure they say isn't coffee our biggest source of magnesium? Am I making that up?

Cynthia Thurlow: I mean I think about getting a lot of those from brightly pigmented vegetables. And I think coffee is very bio-individual because I have some patients that will actually increase their cortisol, which increases their blood sugar. And so, it's figuring out what the right amount is for everyone. I used to have patients that would drink, I don't know, 10 cups of coffee a day. And I was like, how are you functioning? I would be a like nervous, jittery, mess.

Melanie Avalon: Yeah, I mean there's definitely that tolerance that happens. I shudder thinking about how much I drank in college. I don't know why I was thinking coffee was this high source of magnesium. But I think it is definitely like the number one source of something like polyphenols or something in Americans' diets, which is interesting.

Cynthia Thurlow: That is, I would hope it would come from a combination of things and not just something drinkable. But I think Americans just really, like I understand, I love the idea of something warm and my hands like the ritual of that I get, but I don't know, I like getting polyphenols from a variety of things, even bitter herbs and vegetables and things like that.

Melanie Avalon: I looked it up, it is antioxidants for most people. That's crazy.

Cynthia Thurlow: Well, think about how many people are drinking regular coffee as opposed to like understanding that it tends to be a mycotoxin-rich food product and just understanding that there're some nuances to the healthiest options that are out there. I'm probably going to get hate mail from the coffee lovers out there. But that's always the way I think about it. As I think if you tolerate coffee and you enjoy it, that's great. Just try to pick the best quality product that your budget permits.

Melanie Avalon: Yeah, I definitely think like you mentioned those mycotoxins are quite an issue. And then just one other comment about what you're mentioning about the sleep. I'm prepping right now to interview, Heather Moday, she wrote a book about the Immune System and Immunotypes, I think I mentioned it on a previous episode. And something that just stuck with me that she was talking about was sleep and she was saying how like out of all the lifestyle factors like diet, sleep, exercise, sleep is hands down the thing that can give you the fastest return on investment, but basically what you were just saying like with one night's sleep, you can see so many changes and improvements in so many biomarkers, compared to like diet where you have to like takes a little bit and exercise even so, yes, value your sleep is the point. So, anything new with you?

Cynthia Thurlow: Oh goodness, we are finalizing our plans for spring break. So that's been exciting. And every year I plan a spring break trip and no one knows what I've planned. And so, there were some requests at the end of last year they didn't want to go away for Christmas. I was like, "Okay, I got that." And so, we're doing something different. We are flying to Portugal and we'll be in two cities there and doing a variety of historical things and food tours and I'm excited.

Melanie Avalon: Awesome and how are things going with your creatine?

Cynthia Thurlow: Good, it's really exciting, we've got amazing feedback. And from my perspective, women having a better understanding of how it can improve both cognition and muscle health. And it was interesting, I was presenting a research article to some of my coaches today and I was telling them about the role of lowered levels of estrogen, how that impacts muscle protein synthesis, and why in those instances, it's even more important that we're taking exogenous, meaning creatine outside the body because our body-- women actually make 70% to 80% less creatine endogenously, inside the body, this gets exacerbated further heading into perimenopause and menopause. So, I was talking to them about how they were looking at two different groups in this randomized control trial. Women that were taking creatine and not doing any strength training versus women that were taking creatine and doing strength training. And there was no comparison in terms of the net improvement in muscle quality and muscle health. I think on a lot of different levels, what I've been loving is just having the conversation about the unique needs of women. And also identifying that men benefit from taking creatine as well. So, it's going really well, I'm very excited. I'm so appreciative that you encouraged me to create my own supplements.

Melanie Avalon: I'm so excited, I'm really excited as well to hear people's feedback after trying yours. And I just got my notification email that yours is coming, I can't wait to try it. So, I know I've asked you this a lot, "How do I take it, can I take it with food?"

Cynthia Thurlow: You can take it. Typically, what I've been doing is using it in a smoothie, but you can take it with food, you definitely don't want to take it in a fasted state. It's for one of those feeding windows in terms of getting the maximize benefits, but it's a white powder, it's easy to measure, that gives you a complete-- the scoop is for 3 grams. All the research has been done on 3 to 5 grams, 5 grams is I'd be leaning more into individuals that are vegetarian or vegan because their needs are actually increased by virtue of the fact they are not consuming animal-based protein. So yeah, it's super easy to take. It doesn't taste like anything, it blends really easily, thankfully, because I think we've all had powders that are chalky, and don't mix well with water and that's never a good thing.

Melanie Avalon: So, you said it doesn't taste like anything.

Cynthia Thurlow: Mm-hmm.

Melanie Avalon: Really like, nothing?

Cynthia Thurlow: Not to me. I've got this acute sense of taste, I think, which is why I don't like coffee, because it's just too-- I was one of those weird people, anything that I would say I would be like the taste tester a couple 100 years ago to determine if something was poisonous, because I have this crazy acute sense of taste and smell, which is not to my benefit having worked in healthcare for many years.

Melanie Avalon: Wow, oh, I can imagine. I'll probably take it like literally with my food. I'm super weird. I like to take supplements with food like I just eat them. And that's okay, like open capsules and like pour them on things. And like I would order quercetin powder and just like add to my food, I would order all these random things like milk thistle.

Cynthia Thurlow: Oh, you're very adventurous.

Melanie Avalon:  Well, very exciting, so how can people order?

Cynthia Thurlow: Yeah, so you would go to my website and the correct address should be-- www.cynthiathurlow.com/creatine is what it should be. There are all sorts of technological glitches that occur throughout this launch process, it's eliminated, little glitches that we don't think are a big deal and then you realize with coding, any little miss stroke of a key can make things not work properly.

Melanie Avalon: I know it's crazy. I remember when I launched serrapeptase the night before-- the day of because it was a midnight launch. We realized there was a glitch and they had to rebuild my entire website right up until, it was so stressful. Yeah, technology-- and I'm like right now I'm still in this Taylor Swift queue. I'm like staring at the thing. [laughs] 

Cynthia Thurlow: I'm really impressed with your dedication.

Melanie Avalon: I have got to get these tickets. The thing is when they come out, if you know about, you probably don't-- about this verified fan presale that Ticketmaster does?

Cynthia Thurlow: I do not.

Melanie Avalon: So, I learned about it with this, for the different artists they try to make it so that the fans can get tickets without it going through all of these resellers where they jack up the prices so they do this like a special sale where you have to be on their email list and then you have to apply and then you have to be accepted and it seems very arbitrary how they accept you or not. Like my good friend did not get accepted, but I did. So, then if you get accepted, then the day of which was this morning you get in the waitlist, and then you have a code for once you get in to like actually get the seats. But it's been so glitchy I think. Ticketmaster sort of crashed from all the Taylor Swift Fans. So, that's where I am waiting. But okay, sorry, tangents.

Cynthia Thurlow: No, that's super exciting. I'm excited for you.

Melanie Avalon: Last question about the creatine, is there a launch special or coupon code for people?

Cynthia Thurlow: It should be CYNTHIA, it we'll give you 10% off. During the launch we had even more amazing discounts, but now that it is officially on sale, you get 10% off with code CYNTHIA.

Melanie Avalon: Awesome, awesome, awesome. And last question about it. How is your creatine different from other creatines on the market?

Cynthia Thurlow: Well, I think we really did an incredibly conscientious effort to keep it simple, there were lots of ideas that were proposed. And I really wanted it to be creatine monohydrate and without any fillers, to know where it was properly sourced from. And I just think when you get online, and you buy things from Amazon as an example, obviously, there are great things that come from Amazon. But I think when it comes to supplementation, we just have to be careful. And so, we know where this product was sourced from, we know where it's packaged, we know what it's not full of. And I know much to your point about not having fillers and gluten and dairy and soy and other garbagy things that get added to supplements in an effort to keep costs low. This is what I believe to be the most high-quality creatine monohydrate that's available in the market.

Melanie Avalon: Awesome. Well, I can definitely attest to all of that just for listeners who are not familiar, both Cynthia and I work with MD Logic to create our supplements. And the amazing thing about it is the ability for us to really make exactly what we want to make to the highest quality and they test multiple times for heavy metals and toxins and fillers, and it's nice to feel very confident in the products that we're creating. So, I'm very excited for you and the creatine.

Cynthia Thurlow: Thank you. Likewise.

Melanie Avalon: Hi, friends. I'm about to tell you how you can get 15% off of my favorite bone broth, which is an incredible way to open your eating window. Also, for all of you vegetarians and vegans, stay tuned because there's something for you too. I've been talking about the incredible health effects of bone broth for years. Bone broth is so nourishing for our body. It's rich in collagen, which can really support your gut health, your skin, curb cravings, boost your energy, and your immunity. But there are a lot of brands out there, a lot of them have ingredients that I don't like, and making it yourself can also be very time consuming. That's why I am thrilled about Beauty & the Broth. Beauty & the Broth was created by Melissa Bolona. She's an incredible actress and entrepreneur. I've had her on the Melanie Avalon Biohacking Podcast. I'll put a link to that in the show notes. But Melissa started Beauty & the Broth after she realized the profound effect that bone broth was having on her own health, specifically, gut issues and its ability to give her radiant skin perfect for the camera. She founded Beauty & the Broth, which hit everything I could want in bone broth. It uses 100% whole organic ingredients. Yes, it is certified USDA Organic. It is one of the only few bone broth companies in the entire US that has a USDA certification for organic bone broth. It has no artificial flavors, no preservatives, no phthalates, no sugar, and something that I love, no salt. 

Friends, even other bone broth that I really love always have salt added. This doesn't. Her bone broths are made from grass-fed ranch-raised beef and vegetarian-fed free-range chicken bones from Certified Humane USDA Organic Farms and all certified organic vegetables are used the broth as well. There're no antibiotics, no hormones, only the good stuff. Here's the super cool thing about Beauty & the Broth. It can be a little bit of a hassle to transport bone broth. It's heavy, you have to keep it frozen. Guess what? Beauty & the Broth comes in shelf-stable packets with no preservatives that you keep at room temperature and they are in concentrated form. That means that you add back water to reconstitute and you can make it any strength that you like. They're single servings, so you can take them with you on the go, and even on the plane as yes, they are 3 ounces, and they're delicious. Oh, my goodness, friends, they will just make you light up. They're honestly, one of the most amazing things I've ever tasted. And for all of you vegans and vegetarians, Beauty & the Broth has a brand-new vegan broth concentrate. It is USDA Organic and is a slow simmer broth which is reduced into a thick gelatinous gel, you mix it with hot water and turn it into a delicious sipping broth. It features organic mushrooms and chickpeas, ginger, seaweed, and pea protein. It is so delicious. So, definitely check that out.

if you've been looking to finally jump on the bone broth train, do it now and do it with Beauty & the Broth. Melissa has an amazing offer just for our listeners. You can go to thebeautyandthebroth.com or melanieavalon.com/broth and use the coupon code MELANIEAVALON to get 15% off. That's thebeautyandthebroth.com with the coupon code MELANIEAVALON for 15% off. All of the listeners who have tried it ever since I aired my episode with Melissa have talked about how much they love it. It is so delicious, you guys will definitely love it, so definitely check that out. By the way, bone broth does break your fast. This is something that you want to have in your eating window. In fact, it's an amazing way to open your eating window because when you're in that fasted state when you take in bone broth as the first thing, all of those rich nutrients and collagen go straight to your gut, help heal your gut, help with leaky gut, help digestive issues. And again, you can go to thebeautyandthebroth.com and use the coupon code MELANIEAVALON for 15% off. I'll put all this information in the show notes. All right, now, back to the show.

Melanie Avalon: Shall we jump into some questions for today?

Cynthia Thurlow: Absolutely.

Melanie Avalon: To start things off, we have a question from Heather, the subject is "IF." Heather says, "Can you tell us, ladies, what a day of eating looks like for each of you? How much protein and carbs y'all eat and still are able to maintain ketosis? I'm about to receive all three books from both of you in the mail." This question is from actually a few years ago, she's probably talking about my book and then when Gin had two books. "I'm about to receive all three books from both of you in the mail, so, excited. I have been on keto way of eating for over a year and just starting to look into expanding my carb intake XOXO."

Cynthia Thurlow: Well, Heather, thank you for your question. I would say when I was first new to fasting, I didn't track my macros per se. But obviously, Dr. Gabrielle Lyon's work has had a huge influence on me. And so initially, after I met her, I started tracking protein and that's my guide. Now, I don't track macros because I generally don't need to and I just lean into more of an intuitive eating approach. As an example today, I didn't break my fast until gosh, almost 12:30, because I had to drive to DC with my husband for a doctor's appointment. And so, I sat down and had a bison burger, I had three deviled eggs, I had some sauteed mushrooms, a lot of this is just leftover stuff. And I would say that this is a lower-carb meal for me. I tend to hover under 75 grams, under 50 grams, sometimes as much as 100, but I definitely am conscientious and it's not that I don't enjoy carbohydrates. But even the non-starchy variety just depends on the day. And for me, it was eating a meal quickly because I had things I had to do this afternoon. And then my second meal today will probably be, I think we're going to boil some salmon. And I might have salad, we do a lot of food prep in my house just to make meals move along faster. Today is going to be a lower carb day. A higher carb day, I might have 100 to 125 grams of carbs. I just do better, me personally, when I keep my carb threshold about under 75, under 50 a day, but it's never to be restrictive. It's just I lean into what my body needs. Like yesterday, I needed some more carbohydrates, so I had some blueberries as dessert last night and some dark chocolate. But I think for each one of us, it's really determining what makes us feel good, and I definitely carb cycle. On a day when I have more carbohydrates, I may have three meals in my feeding window, open up my feeding window, and just have more discretionary carbs that might be sweet potato or root vegetables. But the protein piece for me is almost always at least 100 to 125 grams of protein a day. And that's really what I lean into. And then the fats as I need to like today I had olives, which I know that Melanie hates. But I love olives, they're like one of my favorite things. What about you, Melanie?

Melanie Avalon: Yes, so I actually really like this question for a few reasons. One, because people ask me a lot what I eat and I don't like to hardcore share because I'm so crazy. And also, I don't want people to eat what I'm eating because it's what I'm eating. But in any case, to answer this, I don't count protein or carbs, I sort of exist within a macronutrient paradigm. So basically, I just do either low fat, high carb, or low carb, higher fat, not really high fat, I don't ever really go like super crazy on the fat. But in general, I'm usually doing a low-fat, high-carb, high-protein approach. And I'm happy that she asked about still being able to maintain ketosis because I'm going to comment on that. I do the one meal a day for four hours or so every night and it is about a couple of pounds of meat and it's a couple of pounds of fruit. And I just looked up the fruit, I probably eat about 200 grams of carbs and fruit, which is a lot mostly from like blueberries. I used to do pineapple. But the thing I wanted to comment on is maintaining ketosis. I actually don't know if I'm going into ketosis during the fast or how deeply I am If so, I haven't measured ketones and forever. Like last time I was measuring ketones was probably back in like 2018. And interesting, I mean this isn't surprising, but I did find that when I was on the higher fat days especially if I added MCT oil, the ketones would go through the roof compared to not so much on the high carb. But what I want to point out is, you don't have to be in ketosis to burn fat. And I think a lot of people can get all the benefits of intermittent fasting without worrying so much about whether or not they're in ketosis during the fast. So yeah, I honestly don't even know if I'm getting into ketosis, but I am eating about probably 200 carbs every night. And who knows how many grams of protein, whatever is in a couple of pounds of meat?

Cynthia Thurlow: Well, I think the big thing is understanding we're all bio individuals. So, asking us is certainly a great question but by the same token understanding depending on how metabolically flexible you are, depending on your age, how much muscle mass you have, can really influence what your carbohydrate threshold is. And certainly, you don't want to be in ketosis 24/7. In fact, that's why I kicked myself out. That's why I actually alternate the amount of carbohydrates that I consume. And I know Ben Azadi and I talk about this quite a bit. If you don't know, Ben Azadi. He's amazing, a friend of mine who heads up the podcast Keto Kamp and has proliferative content around ketosis and ketones and things like this. And so, we want to vary what we're doing day to day and I think that's certainly important.

Melanie Avalon: Like because of this question, I said, at the beginning, I get so nervous about people thinking there's one answer that they have to do what another person is doing when bio-individuality is so key. I'm actually recording with Ben tomorrow.

Cynthia Thurlow: Oh, good, I love Ben.

Melanie Avalon: I've never met him, just through email. So, I haven't like talked to him or anything.

Cynthia Thurlow: No, he's one of the most positive people you will ever meet. Like really and genuinely one of the most positive people. And I mean, we've been friends for several years and have spoken on so many stages together. And my husband knows, he and his fiancé and I know them and, like we just really enjoy each other's company. He's a good person, a good human.

Melanie Avalon: I'm really, really excited about that. So okey-dokey. Shall we go on to our next question?

Cynthia Thurlow: Sure, this is from Robin and the subject is "Chronic pain flare." "I enjoy your podcast and I'm loving the diet. However, I'm having a significant flare-up of my chronic pain and wonder if it is related to intermittent fasting. I've been diagnosed with central sensitivity, chronic Lyme, and fibromyalgia. Is it possible there is another variable play? Always too many variables? My wife suggested I ask you. My internet search didn't yield any answers and I'm hoping you also haven't heard of this happening or if it does happen to some that it will subside as my body adjusts. I've been doing intermittent fasting since mid-April and vary between four to eight-hour windows with only occasional lapses when I've been sick. I really love it, so don't want to stop." Thank you.

Melanie Avalon: All right, Robin, thank you so much for your question. So, I thought a lot about this and I have a very casual answer. And then I have what I found from researching, which did not find the answers I was hardcore looking for. I'll start with the research side of things. So, I did a lot of searching for fasting and chronic pain. There's a lot of studies on fasting helping chronic pain. So, there was a really nice review. I think it was a review, but it was called Intermittent Fasting: Potential Utility in the Treatment of Chronic Pain across the Clinical Spectrum. I had never thought about pain, how it breaks down, like all the different types of pain. So, it talks about like all the different types of pain and like how there're six main types and has this really nice chart about how fasting can benefit most of those types with sources. But just in general if you do a search in PubMed or Google Scholar, there's a lot of studies about fasting benefiting pain, which is not the experience that Robin is sharing. I found another study called the analgesic effect of refeeding on acute and chronic inflammatory pain. And it was speaking to the effects specifically of fasting versus eating on pain perception. It was in rodents, not humans, but some of the interesting findings. So again, I don't know how much of this applies to humans because of the rodent aspect. But they did find that both fasting and feeding helped pain, but that for fasting in the rodents it was only in the second half of the fact that they started experiencing the pain-relieving effects and fasting helped only the inflammatory type of pain and not mechanical, whereas food seemed to help both. Again, that's nuanced I don't know how much of that applies to humans, especially when the majority of the studies that I could find were that fasting helped pain, my casual, non-scientific sort of N of 1 I haven't experienced it but I feel like I've seen all people talking about this, a lot of people will say that when they start fasting, whatever issues they have, can get worse before they get better. And I don't know if it's like a healing crisis or a detox effect or what's going on. I mean it does sound sort of like that rodent study where it said the pain-relieving effects started in the second half of the fast. So, have you heard that Cynthia, where people say that it gets a little bit worse before it gets better with fasting?

Cynthia Thurlow: It's funny, I always think about food-based sources of inflammation that can be exacerbated, especially with someone that has chronic Lyme, I think there's a lot to unpack there. I mean, you've got a chronic inflammatory response syndrome. And I can come at this question with many different angles. More often than not, people feel a whole lot better as they're pulling things out of their diet. I wonder if there's a diet variable that hasn't been examined that may be making things worse in conjunction with fasting.

Melanie Avalon: Yeah, I would encourage you, Robin, to keep on with the fasting, I would imagine there are other variables at play, and I can't see how the fasting would continually perpetually continue to make things worse. I would probably stick it out and see what happens and see if it gets better. And definitely, like Cynthia said, look at other potential issues for what might be going on there with food and things like that. Talking about, Cynthia, where like when people start fasting, they experience things. I don't know if it's because the body is like finally cleaning up and tackling stuff, but I feel like people will experience, I don't like using the word healing crisis because that sounds very woo-woo but do you know I'm talking about in this idea?

Cynthia Thurlow: I do, again, I'm going to come out this as a clinician, and from my perspective, if there's this upregulation of autophagy and there's some degree of deeper healing that's ongoing. And then on top of that their detoxification pathways aren't properly opened. I mean that could be contributory. I'm just looking at this as just from the perspective that we know, we detoxify every day, we poop, we pee, we breathe, we sweat. But the two main sites of detoxification where our body is getting rid of toxins, breaking down medications, etc., two phases that occur in the liver and then the bulk of toxins are then hopefully excreted through the digestive system and the gut. And so, I think there're many variables at play when people tell me that they're having an upregulation in pain, I believe that but obviously, I think that there's probably a component to this that is probably not completely clear in the question. And it's not a criticism of Robin, I'm just saying that chronic pain people just have an upregulation in inflammatory cytokines and other inflammatory processes. And there could be something else going on. When people tell me they have fibromyalgia and they have a tick-borne illness. There's a lot going on. From my perspective, I think it's digging deep, anti-inflammatory nutrition, removing the most common predicators of inflammation in the body, the gluten, grains, dairy, alcohol, sugar, soy in conjunction with fasting can be really powerful. But I would also want to ensure that Robin has taken the steps or is leaning into opening up those detoxification pathways that could be exacerbating why there's a pain response.

Melanie Avalon: Yeah, I think that's great. Another thing I was thinking of, this is not probably what's happening with her, but it's just an example of something where something might get worse before it gets better, people will talk about when they go on, like a carnivore diet, and they have oxalate dumping, things like that where some sort of restriction for whatever reason causes a release of a compound or toxins or a stir up of something else.

Cynthia Thurlow: This plant-based defenses are real thing. I think that for many of us, obviously if you have chronic Lyme, you've had multiple rounds of antibiotics. There's no question you've got some degree of hyperpermeability of the small intestine. There's a lot that can go on. So, from my perspective, those are the people who tend to be the most sensitive to those plant-based defenses, whether it's oxalates, whether it's saponins. There're just so many variables that could be impacting that. And I find that even those of us that are abiding by like a gluten-free diet, I always think about almonds as the best example like they're proliferative and keto and low-carb products. But the oxalates can be a huge hindrance to, really dampening down the inflammatory response in the body. And for a lot of people, they may get pain, others may get diarrhea, they may have abdominal pain. It's interesting I interviewed an oxalate expert on the podcast.

Melanie Avalon: Who'd you interview?

Cynthia Thurlow: Monique, and she trains underneath, who's that woman? It's like Sharon Sandy.

Melanie Avalon: Sally Norton and Susan Owens mixed up.

Cynthia Thurlow: Yes, it's one of the two. And so, she trained with her and she's in a wonderful resource and all her content is leaning in the oxalate. I was stunned at how much I learned. And so, for me, I don't tolerate a lot of the heavier oxalate foods and still don't to this day. And I think a lot of it had to do with the 13 days of being hospitalized, a lot of antifungals, antibiotics for six weeks, and my gut's probably still healing. So, when I look at this, there's a lot of different things that could be going on. But I would start with nutrition as being a huge driver in the detoxification.

Melanie Avalon: Yeah, I'll put a link in the show notes. I had Sally Norton on my show. The oxalate is one of those topics where I don't normally think about it and I think a lot of people don't normally think about it. But then like you just said, when you hear the information about it, it's mind-blowing. It's like, "Oh, maybe this actually is a major issue."

Cynthia Thurlow: Yeah. And I just had Bill Schindler on the podcast. I know you've had him on your podcast. We talked about oxalates and I said if you look at them under a microscope, they look like little crystals. And I said is it any surprise that these plant-based defenses are designed to protect the plant, but in someone who's susceptible to them, like me, this is why my mother, I've got an Italian mother, she's always trying to get me to eat more greens. And I finally had to say, I was like leave me alone about the kale and the spinach. I'm like it doesn't agree with me. And someone else, it's probably absolutely fine. But for me, I know exactly what it does to my digestive system. It just reminds me that, there's a very fine line with a little bit and then enough that will provoke a flare. And I'm just not willing to go there.

Melanie Avalon: Yeah. I'll also put a link in the show notes. My app Food Sense Guide has oxalates as one of the compounds that it shows if people are curious about the levels of oxalates in food. So, you can get that at melanieavalon.com/foodsenseguide and we can put a link to the interviews with Bill Schindler. He's so amazing.

Cynthia Thurlow: He was lovely and it was funny. I make my husband listen to my podcast episodes. He was like he's talking about bugs and he's talking about organ meat and he was like, "I got to meet this guy, he sounds amazing." And I said, "No he's a complete realist." Like, he'll tell you his kids didn't love the insects, but he talks about the value of cricket flour and just being open minded to the fact that back in paleolithic days you just ate what was available. You weren't picky about like I'm only eating muscle meat, I probably would have starved. But yeah, I'm not the most foodie adventurous, I'm not eating the cartilage and organs every day and goodness. I like Pluck though. Have you tried Pluck? 

Melanie Avalon: No, what is?

Cynthia Thurlow: So, it's like an organ meat-based seasoning. It's really good. We'll have to link it up in the show notes.

Melanie Avalon: Wait, that sounds so cool. Wait, it's made from organ meats, but it's a seasoning, wait.

Cynthia Thurlow: Oh, it's a chef that created it, James Berry, mm-hmm. I have had him on the podcast.

Melanie Avalon: Wait, this is so cool.

Cynthia Thurlow: Yeah, and it's really good. And actually, they came out with some new flavors. And so, the spicy is really good. Actually, I like all of them. But we'll link it up, we'll give you my discount code. But unlike anything that can get organ meats, in general, more accessible, to me if I throw it over deviled eggs, it's no big deal. But if I sat down and ate a piece of liver that probably wouldn't happen. So, I think the understanding is trying to make these things accessible. I know Bill does a great job with that. James Berry does a great job with that and he's a chef, and I just really appreciate people trying to find clever ways to get people eating more nutrient-dense foods.

Melanie Avalon: I'm looking this up. Okay, so like their main one, like the normal all-purpose one so it has a blend of liver, spleen, kidney, heart, pancreas with onion, salt, paprika, lemon, pepper, garlic, parsley, mustard seed, thyme. Wonder if they have one that's AIP friendly. Let's see pure. Let's look at the pure one.

Cynthia Thurlow: I think that's just organ meat.

Melanie Avalon: Okay, yeah. And then Zesty Garlic, let me look at that one. I like doing online shopping. Wait, this is so cool.

Cynthia Thurlow: Yeah, and they're really good. And so, James is like a real chef. And I love just how clever he is.

Melanie Avalon: Friends, I want the Zesty Garlic one, it has liver, spleen, kidney, heart, pancreas, and then onion, garlic, lemon peel, salt, carrot, garlic, cabbage, parsley, oregano, marjoram, basil, and thyme.

Cynthia Thurlow: Totally good. And spicy is good, too. We're kind of spicy people. We like a little bit of spice, my husband more so he does than I do. But it's going to be part of our holiday gift list because I think it's just a fun way to get people exposed to eating organ meat in a way that's not scary. Like I'm not going to sit down and eat a plate of spleen although I can respect those that do.

Melanie Avalon: Yeah, and they actually do list on their website if it's AIP or not. Super cool, that never occurred to me, that's smart. And then there's a lot of people like there's some company that makes, it's like breadcrumbs, but it's like made from meat. Do you know what I'm talking about?

Cynthia Thurlow: Oh, is that like the pork panko?

Melanie Avalon: Yeah, I think so. It's like they have it like chicken.

Cynthia Thurlow: Yeah, it's a little salty. I like the idea. We tried it and it was so salty. And I was like, I like salt but it was a little too salty for me.

Melanie Avalon: So, another company actually reached out to me called Safe Catch?

Cynthia Thurlow: Yeah, they reached out to me, I think I told you about the scallops with them.

Melanie Avalon: The scallops you told me about were-- because I read it down to look them up was Seatopia?

Cynthia Thurlow: Oh, they all run together.

Melanie Avalon: Seafood is my thing. So, I've been like taking notes. I literally have written down in my agenda to look up your Seatopia scallops. So, you like those?

Cynthia Thurlow: I thought they were good. I like to buy fish the day of-- that's my husband is a fisherman and likes to go deep sea fishing. And so, he's super picky about seafood. So, we tend to buy it the day that we're going to eat it. So, I think it's super convenient. Like I think ButcherBox is awesome in terms of like, meat shows up at my door, I don't have to go to the grocery store. I'm not 100% sold on seafood being sent to my house. I'm not there yet.

Melanie Avalon: So, I'll comment on the seafood aspect. Often times when you're buying it fresh, it's actually less fresh than frozen. Because frozen, they freeze it right there. And so that stops histamine production, and basically just freezes it in time compared to when you buy it at the store. If it hasn't been frozen in between which sometimes they freeze it and thaw it again. But regardless, it's a longer shelf life where it's been not frozen which is interesting. I think a lot of people don't think about that, which is why I'm all about the frozen. So, the Safe Catch, the reason I really, really like them is they have tuna and salmon and they test all of it for mercury. And I just think this is such a problem, especially with tuna because with tuna, there're so many different species and so many different sizes. So, the mercury levels in tuna can range, some tuna can be low mercury, but some can be really, really high. And so, they actually test, so all of their tuna test to be super low in mercury and the same with the salmon and it comes in, they just sent me a box, but it comes in pouches. So, I'm really, really excited that they reached out to me, they gave me a coupon code. So, this will only be through the end of the year. So, stock up now. And this would be a great thing to stock up on because like I said it comes in pouches. So, you can just stock up. You can get 20% off with the coupon code MELANIEAVALON. I'll put a link to that in the show notes. But their website is safecatch.com, which is easy. But yeah, going back to the fish thing because I'm like such a fish fan, you can always ask at the counter. Like if it's been frozen or not frozen or like what the deal is with it. Oftentimes, it's just a little fun fact at Whole Foods, half of the time this stuff that they have in the fish counter, is just a thawed version of the frozen bags that you would buy in the frozen section. Like they do with the shrimp. They do that with the barramundi, I think they might do it with the salmon. So, it's kind of crazy.

Cynthia Thurlow: Awesome. Now, it's always good to learn about options that are out there that are safer. I think after my mercury issue about five years ago, I've just been very conscientious about sporadically eating fish and not eating it often.

Melanie Avalon: Yeah, once you have that mercury toxicity problem and it's something where you can just stop me because I'm so passionate about this subject. I'll talk about it for an hour, but it's something where you don't see it, like you don't see the mercury in fish. So, if you could see the mercury, I promise you people would not be putting even moderate mercury species of fish into their mouth. I've said this a ton of times but if you look at like the spread and you take a piece of tilapia that has the lowest amount of mercury possible and you compare it to a piece of swordfish that has the highest amount, it can be 300 times. So, if you eat one piece of swordfish that could be like eating 300 pieces of tilapia for the mercury in one meal.

Cynthia Thurlow: My mom would throw a sea bass, like fixation for a long time.

Melanie Avalon: Chilean sea bass?

Cynthia Thurlow: Yeah.

Melanie Avalon: Oh, I know. It's so good.

Cynthia Thurlow: Yeah, and when I tell you it was like years. That's like every time we showed up, she went from being vegan to eating fish and eggs and we were very happy about this. And now she's back to eating meat. But the joke was, she would buy the most massive piece of sea bass and sea bass is wonderful, but it's like one of those overfished fishes that's why it's so expensive, that's the other thing is like trying to get acclimated, like being open to trying different things. I think that's important, just being open minded is certainly very helpful.

Melanie Avalon: Yeah, definitely. When it comes to the fish. I actually have a blog post, I'll put it in the show notes. I talk about the fish that I will eat because I really only will eat. I'm very, very limited. I'll eat scallops and shrimp because they're so low on the totem pole. I'll eat farm salmon, I won't even eat wild salmon with the exception of this Safe Catch, which is very exciting. And then I eat responsibly farmed tilapia if I know the source and then I'll eat Australia's barramundi and then when I go out, I might get like, sole or trout or something. It's funny Gin and I had completely different food tastes. So, she was like not about the fish at all. [chuckles]

Cynthia Thurlow: I grew up at the shore, for anyone that's from New Jersey, the shore, the Jersey Shore. And so, we had a lot of fish growing up. And it wasn't really until, probably until I got to Baltimore, because Baltimore's on the water and there's just a lot of like crabs. And I mean, you just eat a lot more shellfish and fish in general. And then I met my husband who's from Annapolis, and we don't eat a ton of fish because my kids don't love it. And it just isn't worth it, it's expensive. They like shrimp, so we do shrimp, but my husband and I will usually get fish for ourselves and then give the teenagers the meat, which is what they want.

Melanie Avalon: Yeah, it's interesting, that fish seems to be more of an acquired. "Oh, my queue is moving, okay, okay, I'm sorry, well, okay, okay. I might have to-- Oh, it's moving, I'm like 1,288 people in front of me.

Cynthia Thurlow: Oh my God.

Melanie Avalon: For the past five hours it's been at 2,000 plus and now it's just oh, 1125, I'm going to get in in a second. Okay, okay, I will just say about the fish. Sorry, this is real-time, real-time Melanie getting her Taylor Swift tickets. 950, I'm going to have to jump it a second, 762. I'll just say about the fish really quickly. It's interesting that it seems to often be an acquired taste. I feel like kids shy away from it. 

Friends, I'm about to tell you how you can get 50% off a product that has truly changed my life. Do you experience stress, anxiety, or chronic pain? Do you have trouble sleeping at least once a week? If you do, trust me, you are not alone. I personally have explored so many avenues for how to have a healthy relationship with stress and finding the world of CBD oil has been absolutely incredible for that. After doing more and more research, I realized just how incredible the health benefits of CBD are. CBD regulates your cannabinoid system, kind of like an adaptogen, making you feel better naturally. It's not addictive, it's not a crutch, basically it's just helping your body function better when it comes to stress, anxiety, pain, and sleeplessness. I take it daily for my mood and the effects are profound. In fact, I even got robbed last year and I went from crying with stress and anxiety to taking some Feals and laughing. I said to my mom, "Mom, see how effective this is?" Due to all of its health benefits, we knew we wanted to partner with a CBD company for the podcast. But I have very stringent criteria. You guys know this. So many brands approached us and I kept just saying, “No,” because nothing fits all of my criteria. I wanted CBD oil that was a full spectrum, tested for purity, organic, made with MCT oil as the carrier, and that I actually experience benefits from. That's a pretty tall order to fill. We said no to a lot of brands, and then Feals came along, and it was meant to be. I personally tried it out and started seeing massive effects on my sleep and stress. Feals is so easy to take. You can just put a few drops under your tongue and you'll feel the difference within minutes. I truly do feel it within minutes. 

Of course, it is important to remember that CBD works differently for everybody based on your own unique cannabinoid system, so you might need to work to find your perfect dose. Experiment over the course of a week or so and you may find that you need more or less depending on the effects that you're looking for. I'm also super grateful because they have an incredible offer for our audience. You can start feeling better with Feals. Become a member today by going to feals.com/ifpodcast and you'll get 50% off your first order with free shipping. That's feals.com/ifpodcast to become a member and get 50% automatically taken off your first order with free shipping, feals.com/ifpodcast. 

When you get that offer, you'll be joining the Feals community and you'll get Feals delivered directly to your doorstep every month. You'll save money on every order and of course, you can pause or cancel anytime. So, definitely try it out for the first month with our code for 50% off and see how it works for you. We'll put all this information in the show notes. All right, now, back to the show.

Melanie Avalon: Okie-Dokie, shall we go on to another question?

Cynthia Thurlow: Yes.

Melanie Avalon: So, we actually have two questions and they go together, sort of, they're similar topics, so I thought I would read them together. So, we have a question from Therese. The subject is "Repetitive routines or mix it up." And Therese says, "Hi, love your podcast." I recently started IF and the first weeks, I simply followed the 16:8 method. I found an app that has great programs and found a program for weight loss and the setup seems to be switching it up with different intervals of eating and fasting. I think of it almost as when you exercise you get best results when you switch it up by doing both cardio strength and different types of intervals. Does weight loss via IF get better results when you're not letting your body get used to a steady rhythm, but rather surprise it with different internal windows of fasting and eating." And then James, his subject is "Constantly changing fasting windows," and he says, "I started IF about a month ago using the BodyFast app, which recommends a different program every week, 24-hour fast 16:8, 20:4 and everything in between to prevent your body getting used to a pattern. I also move fasting periods myself to allow social occasions. I have heard you talk positively about keeping the same fasting rhythm. What is your view on switching schedules in these ways?"

Cynthia Thurlow: Well, Therese and James, if you are at all familiar with my work, I am a huge proponent of variety as it pertains to nutrition, exercise, and a fasting program. Obviously, for women that are still menstruating there are times in the menstrual cycle when we should lean into more fasting as opposed to others when we should not. Men and menopausal women have the advantage of not having as much hormonal fluctuation. I typically do recommend-- our bodies get lazy, if we are doing the same thing, think about if you did the same workout at the gym every time you went, over time your body gets acclimated and you're no longer challenging it. And so, we want to think about exercise and a fasting regimen is a form of hormesis, beneficial stress in the right amount at the right time to keep things changed and challenged. And I'm absolutely a proponent of different types of exercise, which includes strength training, high-intensity interval training if that's appropriate for you, NEAT, which is just being physically active throughout the day that's not structured exercise. And then, leaning into the fasting piece. In fact, I was listening to a video of Chris Kresser today and he was presenting some new research, looking at women in particular in fasting and a lot of it goes back to things that I talk about, you have to have a large enough window to get enough protein in in your feeding window, not having to narrow the window, getting concerned with over fasting losing muscle mass. And so, there's a fine line for each one of us. And for me personally and I'm just going to use myself as an example, I'm in a very healthy weight, I don't want to lose muscle mass. I don't do long fasts. There are people to do them and if you have a lot of weight to lose, you're struggling a bit maybe you needed to have like a digestive reset, you have more latitude with that than someone that's already at a goal weight or already pretty metabolically flexible. I think it's a very individual decision, but I'm absolutely a fan of varying what we eat, when we eat, and not doing the same types of exercise every day. What do you think, Melanie?

Melanie Avalon: Yeah, so I've thought about this a lot in general, with the exercise and everything, I definitely agree that mixing it up is so key including all those different types, like you were saying, because that's really most in line with how we would have evolved as a species, we weren't going to the gym and like working out for 30 minutes every day or like doing the same thing every single day, and we were moving functionally, we weren't just exercising this one muscle to, really aesthetically the way it looks. So, health-wise, exercise, mixing it up, I think is great. With fasting, I think as well, it can be great to mix things up. But I think the complicated nuance is, because I just know how I personally am, which for me, like it really works following the same fasting schedule. And when I go off of it, I don't feel as well. And I think part of that might have to do with the peripheral clocks of our body are driven independent within themselves. I was actually just reading about this in a book that I'll probably talk about next episode because have you heard of-- I think I mentioned it before, it's the Oldest Cure in the World?

Cynthia Thurlow: No, I have not.

Melanie Avalon: It's by Steve Hendricks, it came out September 6 and it's the deepest dive into the history of fasting I have ever read. So, the subtitle is Adventures in the Art and Science of Fasting. I'm going to interview him which is really exciting, but its mind blowing some of the things I've been learning. But in any case, that part I was reading last night was about the SCN. So, the master clock in our body, which light affects and which drives a lot of our circadian rhythms. But then all of our cells have peripheral clocks and they can function on their own. So, they can be informed by the SCN, but they can also be completely informed on their own. And so, eating is actually a very intense clock within us and it's on its own rhythm and it's often based on how we're eating. And so, the reason I'm bringing this up is I find for me personally that if I follow my same fasting window of a one-meal-a-day situation at night, then I feel good during the day, I'm not hungry during the day, I'm hungry at night. I feel good at night, I find it that when I break it, it messes with that clock for me, and I just get ravenous. So, like if I were to like widen my eating window, which works really well for a lot of people like to have those days where they have a longer window. For me it like just doesn't work, it would just make me hungry and miserable and not feeling good. And so, I wonder if with the fasting it's something where people really should take it individually for how it affects them. And, how do they do with mixing it up or not mixing it up? I think some people will do better with mixing it up and some people won't. Do you have thoughts on that concept?

Cynthia Thurlow: I mean, I do. I just think overall if the bulk of the population here in the United States is not metabolically flexible, they have to change things up. I see where you and I are both coming from, honoring our bio-individuality, honoring the fact that I always call you the unicorn. And I mean that in the most affectionate way, like manner, not in a pejorative way. But like, I can get up early, I have to go to bed early, you can stay up late, you like to sleep in. So, it's like figuring out what works for our bodies. But knowing that the bulk of people are metabolically inflexible here in the United States and most westernized countries, changing things up in some capacity, even if it's, you lift an extra day that week, or maybe you go an extra hour without eating or maybe you shorten your window, like some degree of flexibility I think is important for us. And that's what I feel like intrinsically. And certainly, after coaching 1000s of people through this process, there are always exceptions, so let me be very clear. But I feel like most of us need some degree of alteration in schedule. Today's a good example, over the last several months, I've been leaning into eating a little earlier in the day and closing my window a little earlier and that has worked really well for me. But today, I didn't eat till I came home. So, I had an unintended almost 20-hour fast. And that's not my norm. But I was like, I'll be totally fine. I had a big meal, I'll have one more smaller meal before I go to bed, and I'll be good. Unfortunately, when I trained 1000 years ago, the mindset and methodology was you treat every patient the same in terms of if they have blood pressure problems, everyone starts with this medication at this dose. And I've just learned to be a little more thoughtful and a little more individualized. So, some type of variation of what you're doing it doesn't have to be dramatic, can be very helpful.

Melanie Avalon: I'm really glad you said that nuance and that's something I was actually going to comment on. I wasn't quite sure how to say it and I think you said it really well. So, for me, the way I would bring in variability in a way or switching things up would be like fasting a little bit longer. Like it would be like a slight tweak rather than just a completely different eating window or I think I could get similar benefits possibly by changing completely what I'm eating in my eating window, like, be it macro wise or whatever. So, or even like a low-protein day just to like switch things up, or switching to a low-carb day to switch things up. I definitely think there is some magic there with the metabolic [unintelligible [01:03:13] piece. I do wonder though if for some people just sticking it out, at least while they're metabolically inflexible to a certain window might be important until they're metabolically flexible. I don't know if I'm articulating it correctly.

Cynthia Thurlow: No, no, no, I totally agree with you and in fact, I had someone on Instagram the other day. And I know of her, she's very thin, she's an exercise person. She kept saying I don't know why you don't just tell people to intuitively eat. And I said that works fine if you're metabolically flexible, but if you are not, you can't and to think that everyone can is pejorative. And so, I have to very politely say that every time because she always comes back and says, "Don't tell women over the age of 50 they can't do this and this and this." And I'm like, "Well, maybe you're an outlier." But generally speaking, I'm trying to come from a place of kindness, but it's clearly a triggering topic. I think what I hear you saying is very aligned with what I think that we have to be gentle and kind and realize that some people are ready to jump in feet first and some people have to like dip their toe in the pond. They're terrified of adjusting what they're doing and so just acknowledge what resonates for you what feels good. We would never advocate that people do something that's beyond their comfort level. Like if you said to me, I want you to play to organ meat, I would struggle with that I have to be completely upfront, it might be just as scary as suggesting someone to change their feeding window. So, I think just entertaining the possibility of making subtle adjustments can be beneficial.

Melanie Avalon: Yeah, I cannot agree more and it's really glad to hear your thoughts about that. I often wonder, especially in the beginning when people are fasting if they hadn't flexed their fasting muscle yet, they might want to switch things up, but it's because they haven't stuck to it long enough to really get in the flow of fasting. So, I get nervous about people trying to be too intuitive, too soon. Some people are great though being intuitive, but some people aren't. You just have to know who you are and what works for you.

Cynthia Thurlow: Yeah, unfortunately, I sometimes see very metabolically flexible people shaming other people for not leaning into intuitive eating. I'm like, they can't it's not that they don't want to, the hormonal regulation in their body is off and they just can't lean into that. So, I think that we have to be kind and open minded and compassionate, I think that goes a long way.

Melanie Avalon: Exactly, even for me, it would be really, really hard. And it's not a skill that I feel like I need to learn. I don't feel like I need to be able to intuitively eat a brownie. Maybe if I eat a brownie that makes me really cravy and want more food and maybe that's just the way it is. And maybe I can just know that about myself and not feel bad that I can't, moderate things like that. I think it should be okay if you know that certain foods are troublesome for you to abstain if that makes you happier.

Cynthia Thurlow: Yeah, no, no I think it's interesting. The thing that I'm always intuitive about is carbs, I don't count carbs, but I have a good sense of how much I'm eating. And so, like yesterday is a good example, I wanted blueberries. And by some miracle, my 15-year-old hadn't eaten them all yet. My husband bought them on Sunday. And usually, he finishes off any fruits that's in the house within 24 hours. And so, I had some blueberries and my husband was like, I'm actually glad to see you eating some blueberries. I said, "Well, I wanted them." And it was like, my body wanted something healthy, and I'll lean into that. And so that's the intuition. But I acknowledge that not every person and quite frankly if we look at statistics 7% to 8% of Americans are metabolically flexible. So, the average person can't do that. I think it can be validating to hear that and also gives people something to work towards.

Melanie Avalon: All righty. Well, this has been absolutely wonderful. So, a few things for listeners before we go. If you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. The show notes for today's episode will be at ifpodcast.com/episode295. You can follow us on Instagram. I am @melanieavalon, Cynthia is @cynthia_thurlow_ and I want to apologize to you, Cynthia, for my craziness today and to the audience for my craziness, but I have the Taylor Swift tickets now. [chuckles]

Cynthia Thurlow: Yeah, so you got your tickets. I was saying to Melanie, the ticket prices have gotten so insane. I was like how do young people afford to go. I went to so many concerts when I was a teenager and a 20-something, kind of makes me sad.

Melanie Avalon: I know. It's crazy.

Cynthia Thurlow: That's probably why I have tinnitus. I have chronic tinnitus, a chronic ringing in my ears, and my working hypothesis from my ENT, it's all those concerts you went to and I was like probably Red Hot Chili Peppers was especially loud many years ago.

Melanie Avalon: Oh, I bet. So, we're going to like rock and roll-type concerts?

Cynthia Thurlow: I've been to everything. It runs the gamut from alternative music when I was in college is now considered very mainstream. But I've seen Red Hot Chili Peppers, I've seen U2 multiple times. I'm dating myself, but yeah, but now it's like I have no interest in being in a big loud crowd. I'm like okay I can watch everything online, I'm good. [laughs]

Melanie Avalon: Well, I go to concerts. I'm going to Mannheim Steamroller in a few weeks and I'm going to Trans-Siberian Orchestra, but I don't normally-- and I go to musicals that doesn't count. [laughs] I know I'm not a concert person except for Taylor Swift.

Cynthia Thurlow: Well, I'm very excited for you.

Melanie Avalon: So "Oh, my goodness." Okay. Well. This has been wonderful. Thank you again, sorry again, and I will talk to you next week.

Cynthia Thurlow: Sounds good.

Melanie Avalon: Bye.

Thank you so much for listening to The Intermittent Fasting Podcast. Please remember everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team, administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and re-composed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Oct 09

Episode 286: Thyroid Regulation, Iodine, Fasting For Your Cycle, Insulin, Glucagon, High Protein Diets, Surgical Menopause, Prescription Medication, And More!

Intermittent Fasting

Welcome to Episode 286 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

BUTCHERBOX: Grass-Fed Beef, Organic Chicken, Heritage Pork, Wild-Caught Seafood: Nutrient-Rich, Raised Sustainably The Way Nature Intended, And Shipped Straight To Your Door! For A Limited Time Go To Butcherbox.com/ifpodcast And Get A 10 oz New York strip steaks and 8 oz of lobster claw and knuckle meat FREE in your first order!

BEAUTY AND THE BROTH: Support Your Health With Delicious USDA Organic Beauty & The Broth Bone Broth! It's Shelf Stable With No Preservatives, And No Salt Added. Choose Grass Fed, Grass Finished Beef, Or Free Range, Antibiotic And Hormone-Free Chicken, or Their NEW Organic Vegan Mushroom Broth Concentrate! The Concentrated Packets Are 8x Stronger Than Any Cup Of Broth: Simply Reconstitute With 8 Ounces Of Hot Water. They’re Convenient To Take Anywhere On The Go, Especially Travel! Go To melanieavalon.com/broth To Get 15% Off Any Order With The Code MelanieAvalon!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get A 10 Oz New York Strip Steaks And 8 Oz Of Lobster Claw And Knuckle Meat FREE In Your First Order!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

The Melanie Avalon Biohacking Podcast Episode #12 - Elle Russ

Ep. 129 – Middle Age, Menopause, and Mindset: How These Components Affect Your Thyroid Health with Elle Russ

Ep. 105 Thyroid Physiology and Chronic Illness – with Dr. Eric Balcavage

Ep. 166 How to Maintain a Healthier Thyroid: Interesting Thyroid Physiology Health & Preventative Care with Dr. Eric Balcavage

The Melanie Avalon Biohacking Podcast Episode #1 - Dr. Alan Christianson

Ep. 154 How to Normalize Your Thyroid Function: What You Can Do To Help Support Your Body with Dr. Alan Christianson

Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist, And Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

Text "AVALONX" To 877-861-8318 For A One Time 20% Off Code for avalonx.us

BEAUTY AND THE BROTH: Go To melanieavalon.com/broth To Get 15% Off Any Order With The Code MelanieAvalon!

Listener Q&A: Ashley - Struggling with consistency

Listener Q&A: Monica - 3rd time is a charm?

High dietary protein intake, reducing or eliciting insulin resistance?

Effects of high-protein diet on glycemic control, insulin resistance and blood pressure in type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials

Protein: metabolism and effect on blood glucose levels

Ep. 109 How To Transform Your Health With Diet And Exercise – With Dr. Ted Naiman

The Melanie Avalon Podcast Episode # 30 William Shewfelt And Ted Naiman

The Melanie Avalon Biohacking Podcast Episode #94 - Marty Kendall

Listener Q&A: Jessica - Menopause, HRT, etc

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 286 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time, and get ready for the Intermittent Fasting Podcast.

Hi friends, I'm about to tell you how to get two grass-fed, grass-finished 10-ounce New York strips and one-half pound of sustainable wild-caught lobster meat all for free? Yes, for free. We are huge fans around here of a company called ButcherBox. They deliver 100% grass-fed, grass-finished beef, free-range organic chicken, heritage-breed pork, that's really hard to find, by the way, and wild-caught sustainable and responsible seafood shipped directly to your door. When you become a member, you're joining a community focused on doing what's better for everyone. That includes caring about the lives of animals, the livelihoods of farmers, treating our planet with respect and enjoying deliciously better meals together.

There is a lot of confusion out there when it comes to transparency regarding raising practices, what is actually in our food, how animals are being treated. I did so much research on ButcherBox, you can actually check out my blog post all about it at melanieavalon.com/butcherbox. But I am so grateful for all of the information that I learned about their company. All of their beef is 100% grass fed and grass finished. That's really hard to find. They work personally with all the farmers to truly support the regenerative agriculture system. I also did an interview with Robb Wolf on my show, The Melanie Avalon Biohacking Podcast, all about the massive importance of supporting regenerative agriculture for the sustainability of not only ourselves but the planet. This is so important to me. I'll put a link to that in the show notes.

The value is incredible, the average cost is actually less than $6 per meal. And it's so easy. Everything ships directly to your door. I am a huge steak lover. Every time I go to a restaurant, I usually order the steak. Oh, my goodness, the ButcherBox steaks are amazing. And we are so excited because ButcherBox has an incredible offer just for our audience. You can get some of those steaks for free and lobster to go with it. You can go to butcherbox.com/ifpodcast and get two 10-ounce, grass-fed, grass-finished, New York strips and one-half pound of wild caught sustainably raised lobster meat all for free in your first box. Yes, completely free. That's butcherbox.com/ifpodcast and we'll put all this information in the show notes.

And one more thing before we jump in. Are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense, because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting. It's actually our skincare and makeup.

As it turns out, Europe has banned over eight thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disruptors, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup maybe playing a role in that.

Beyond weight gain and weight loss, these compounds have very detrimental effects on our health, and they affect the health of our future generations. That's because ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years. Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means, when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves.

That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so, you can truly feel good about what you put on. And friends, these products really, really work. They are incredible, they have Countertime for anti-aging, Countermatch for normal skin, Countercontrol for acne and oily prone, and Counterstart for sensitive. I use their overnight resurfacing peel and vitamin C serum every single night of my life. And their makeup is amazing. Check on my Instagram to see what it looks like. Tina Fey even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more.

You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20, to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well.

And lastly, if you're thinking of making Clean Beauty and Safe Skincare, a part of your future, like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20, to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show.

Hi everybody and welcome, this is episode number 286, of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with Cynthia Thurlow.

Cynthia Thurlow: Hey, Melanie, how are you?

Melanie Avalon: Good, how about you?

Cynthia Thurlow: We were just commiserating about this. But when your thyroid medication gets changed, it can sometimes be a little bit of a bumpy ride. So, I'm feeling I need to prop up my eyes with toothpicks today.

Melanie Avalon: I've been on the same bus that you've been on with trying all different forms of thyroid medication. It's just so complicated because there's so many opinions and there's so many options. And it can be hard to really find what works for you.

Cynthia Thurlow: Totally, I think if anyone that has an underactive thyroid that's listening, I know you understand [chuckles]. I know you understand, so I'm trying to just wait it out. My functional medicine doc is encouraging me to wait it out another week and get my labs checked. Goodness, I feel I need a power injection in the afternoon because I feel like I need a nap. And who has time for that every day?

Melanie Avalon: Well, I will say, this actually made me think about this. Sort of recently, I was in a period where I was feeling I needed a nap every day. And I just realized you know how you don't really notice when the negative things are gone? I just feel when I'm experiencing something negative once it actually goes away, I don't you may normally realize it. I just realized, "Oh, I haven't been needing a nap every day." I think the difference is, when I got sick a few weeks ago and started really high dosing the NMN and I stayed on the NMN every day at a higher dose. I don't need naps anymore. I think that's what it is, I don't know what else it would be. Although I have realized I feel a little bit more wired at night as well. So, I'm maybe I'm too high dosing. So, that's a benefit. I didn't used to be a nap person, and then I was and I'm not. How about you?

Cynthia Thurlow: Every once in a while, might need it but I generally, power through my day. And on a lot of levels, the fact that I consistently every single day, I'm this tired, the only variable that's changed is the thyroid medicine. And I knew this would happen because what typically happens is I get insomnia. And then, I have a crash in the afternoon. That has been a consistent pattern. Even though they've increased my T4, they lowered my T3. And my functional medicine doc said, and I quote, "You have the most interesting thyroid panel I've ever seen." And I said I don't want to be interesting I just want to be normal. I'm trusting the process. And he's absolutely brilliant and one of the smartest physicians I've ever met, so I am trusting in the process but in between, I will need naps in order to function.

Melanie Avalon: Do you think you'll increase your T3?

Cynthia Thurlow: He might. I think it's interesting, I'm supposed to have lab, he wanted labs drawn two weeks after I started the medication. So, I've already got that appointment set up, and I knew as soon as I started, I knew that there would be this bumpy-- this has been the pattern every single time they've changed my medications. In fact, I thought for a moment, because I keep all my old medicines just to describe to people, I'm not kidding, I really have been on 10 different prescriptions in the past two years. And it's a bag of thyroid medicine. And my husband was like, "What is that?" And I was like, "I don't know, it's a trophy. I'm keeping this for posterity's sake, I'm not sure." But to really demonstrate this is what people go through. And I'm a clinician and we still haven't gotten it right, so it goes on to just suggest that many people listening, are probably struggling with the same thing. So, that's why I wanted to share, to be transparent and say, "Yes, I'm a clinician. But yes, I'm still struggling to get the right combination of medications."

Melanie Avalon: I don't love that you're experiencing that. But [chuckles] I love it that's your approach. And yeah, some good resources for listeners. Have you interviewed Elle Russ?

Cynthia Thurlow: I have Elle and Eric Balcavage, Balcavage, sorry, I just mangled his last name, he's wonderful. He does a great Thyroid Thursday on Instagram. So does a lot of teaching. I think he's a great resource. And we both have had Alan Christenson on, but I would say Eric does a lot of didactic teaching as a clinician, which I love. And then Elle is all about empowerment, which is fantastic.

Melanie Avalon: Yeah. And Dr. Alan Christianson, who you just mentioned, it's funny, when I first met him, I was really struggling with my own thyroid panels. He is the nicest person ever because I literally just met him, and we've been vaguely emailing actually about intermittent fasting stuff. We were debating the literature on it. I guess at some point, my own thyroid issues came up and he was so nice. At one point, he was like, "Well, send me your labs to look at." I sent them to him, and he called me, he was like, "I have to talk to you about this [laughs] We have to get this fixed now." I was like, "Oh my goodness. You're the nicest person ever." He has a book called The Thyroid Reset Diet. He was actually my first episode of the The Melanie Avalon Biohacking Podcast.

Cynthia Thurlow: You what's funny, so fast facts. Alan was part of my Mastermind. When I joined it, and I recall the very first time I met him in person, I was sitting next to him at a lunch, and I was trying to be really cool. Because sometimes when you meet these people that you've been following them for years, and then you're socially around them. All I say to myself is, "Just be cool. He is a normal guy." And he is as nice as nice could be. I just think Midwesterners in general are just such nice, down to earth, human beings. And he really is as nice as he appears to be, and very quiet and introverted and I really enjoyed the time that I had with him, but I think he's a great resource.

Another funny thing to share with you is that the podcast team that I had at the time that I recorded a podcast with him about his new book about iodine, the podcast title was Intermittent Fasting and Thyroid Health, and I just about had a minor heart attack, because he's not a big fan of Intermittent Fasting. And I literally was like, "You cannot put that out. You cannot do that." And then, I had to explain the context. I was like, that is absolutely the worst title you could ever come up with.

Melanie Avalon: It's funny, the way I met him actually was-- I don't know if it was him or it was probably his publisher, or publicist, or somebody. They pitched him to come on this show. And it was for his metabolic reset diet. And literally at that time, he literally had a video on YouTube about-- it was basically deconstructing intermittent fasting. I wanted to engage with them. But Gin was not too excited about the idea. And so, that's why I started talking to him via email and started discussing the studies. And he actually took down that video, I think, after it because we talked about it some more and I think he realized there was a slightly more nuanced perspective on that specific content that he had created. And I just thought that was so impressive. But yeah, I know, I love his work. He has the thyroid reset diet, the adrenal reset diet. What's the book on iodine called?

Cynthia Thurlow: No.

Melanie Avalon: That's the thyroid reset diet.

Cynthia Thurlow: Yes.

Melanie Avalon: I'm still haunted by that. I still don't know what I think about it.

Cynthia Thurlow: I don't agree, politely I don't agree.

Melanie Avalon: I need to reread it, because it's interesting, because it's so contrary. It's not like it's slightly different than the popular idea. So basically, for listeners, a lot of people in the functional health world, and I guess nonfunctional as well, advocate needing more iodine to help thyroid and just health in general. And a majority of the book is about how iodine is actually the issue, and we actually need to be on a low-iodine diet. So, yeah, I don't know.

Cynthia Thurlow: I think it's important to entertain the possibility that there may be aspects to that argument that are applicable, but I don't necessarily agree but I don't have enough background, I'm not an iodine specialist, but I do ask my functional medicine friends and I would say iodine is a controversial issue because you have people like Brownstein, who is pro iodine, and wrote the book, The Iodine Crisis. And then, you have other doctors that feel differently. So, we have to agree to disagree. And I don't feel I know enough to feel I could take a stand on it. I'm in a state of flux.

Melanie Avalon: Reading his book, it's very convincing. And I do think there's probably a lot to maybe the difference between people who are eating a conventional diet, so they're getting iodized salt, compared to people who might not be having conventional salt, and so not having that source, I do wonder what role that plays. I do know iodine-- I know I've shared this on the show before I don't know if I've told you before. It's the only supplement that I experimented with that I had such obvious scary reaction that I was like, "I'm never taken this ever again." My eyes literally turned bloodshot red.

Cynthia Thurlow: Really?

Melanie Avalon: Yeah, that's kind of frightening [chuckles]. I remember I can't-- I can't even know if I can go to work. It was when I was still waiting tables. Yeah, so we will put links in the show notes. To the interviews we have had with all of these individuals.

One little announcement I do want to share with listeners, by the time this comes out, I feel bad because I think that this special will have already ended but the concept is still available, which is all the more reason you need to be on my email list for my AvalonX Supplements, which is avalonx.us/emaillist. And also, you can actually get text updates, and a 20% off one time code. I'm so excited, I set up text updates. If you text 'AvalonX' to 877-861-8318-- I'm just going to emphasize for clarity, Cynthia, have you ever set up a text service?

I have not. It's really funny because I say text 'AvalonX', all of the iterations I get of people texting that it's not AvalonX, people will text Avalons, or, give me the code or all these things. I'm like, "No, you have to text just the word AvalonX." So, it's a kind of like-- I don't know, it's just really funny to see all the messages. So, that's A-V-A-L-O-N-X to 877-861-8318. And if you are on that list, you would have known that we launched magnesium subscriptions. And we actually had a two-week window where you could get grandfathered in for life at a 25% discount, which is the largest discount we should technically probably ever do. And you get it for life as long as you stay on the subscription, which you can also pause. So, that's amazing, if you didn't snag the 25% you can still get a subscription now at 15%, so that's an option. Anything else from you, Cynthia?

Cynthia Thurlow: I am hopeful that we will finalize a package for the creatine so that I can get a date that this will be available. That is, I've got my fingers crossed.

Melanie Avalon: I'm very excited for you. Then someday, you'll have subscriptions on that as well, probably?

Cynthia Thurlow: Yes, you'll be able to tell me all about text options too.

Melanie Avalon: That's the thing I've learned, is be very clear in what people text to you.

Cynthia Thurlow: Keep it simple.

Melanie Avalon: It is simple, but people just extrapolate and text all the things and I'm like, "No, that is not what it says."

Cynthia Thurlow: It says not direct access to Melanie 24/7.

Melanie Avalon: Is not what it says.

Hi, friends. I'm about to tell you how you can get 15% off of my favorite bone broth, which is an incredible way to open your eating window. And all of the bones and this broth, Beauty & the Broth, are grass fed with no antibiotics or hormones and are traceable. Also, if you're suffering from mold or any autoimmune disease, bone broth is a basis of a lot of those protocols. But you want to make sure you are getting the best of the best. That's why I love Beauty & the Broth. Also, for all of you, vegetarians and vegans, stay tuned, because there's something for you too.

I've been talking about the incredible health effects of bone broth for years. Bone broth is so nourishing for our body. It's rich in collagen, which can really support your gut health, your skin, curb cravings, boost your energy and your immunity. But there are a lot of brands out there, a lot of them have ingredients that I don't like and making it yourself can also be very time consuming.

That's why I am thrilled about Beauty & the Broth. Beauty & the Broth was created by Melissa Bolona. She's an incredible actress and entrepreneur. I've had her on the Melanie Avalon Biohacking Podcast. I'll put a link to that in the show notes. But Melissa started Beauty & the Broth, after she realized the profound effect that bone broth was having on her own health, specifically gut issues, and its ability to give her radiant skin perfect for the camera. She founded Beauty & the Broth, which hit everything I could want in bone broth. It uses 100% whole organic ingredients. Yes, it is certified USDA organic. It is one of the only few bone broth companies in the entire US that has a USDA certification for organic bone broth. It has no artificial flavors, no preservatives, no phthalates, no sugar, and something that I love, no salt. Friends, even other bone broth that I really love always have salt added. This doesn't.

Her bone broths are made from grass-fed, ranch-raised beef and vegetarian-fed free-range chicken bones from certified humane USDA Organic Farms. And they are all traceable, meaning you can find exactly where these bones came from. And all certified organic vegetables are used in the broth as well. There's no antibiotics, no hormones, only the good stuff.

And here's the super cool thing about Beauty & the Broth. It can be a little bit of a hassle to transport bone broth. It's heavy, you have to keep it frozen. Guess what? Beauty & the Broth comes in shelf-stable packets with no preservatives that you keep at room temperature, and they are in concentrated form. That means that you add back water to reconstitute, and you can make it any strength that you like. They're single servings, so you can take them with you on the go, and even on the plane as yes, they are 3 ounces, and they're delicious. Oh, my goodness, friends, they will just make you light up. They're honestly, one of the most amazing things I've ever tasted. And for all of you vegans and vegetarians, Beauty & the Broth has a brand-new vegan broth concentrate. It is USDA organic and is a slow-simmer broth, which is reduced into a thick gelatinous gel. You mix it with hot water and turn it into a delicious sipping broth. It features organic mushrooms and chickpeas, ginger, seaweed, and pea protein. It is so delicious. So, definitely check that out. 

So, if you've been looking to finally jump on the bone broth train, do it now and do it with Beauty & the Broth. Melissa has an amazing offer just for our listeners. You can go to thebeautyandthebroth.com or melanieavalon.com/broth and use the coupon code, MELANIEAVALON, to get 15% off. That's thebeautyandthebroth.com with the coupon code, MELANIEAVALON, for 15% off. All of the listeners who have tried it, ever since I aired my episode with Melissa, have talked about how much they love it. It is so delicious, you guys will definitely love it. So, definitely check that out.

By the way, bone broth does break your fast. This is something that you want to have in your eating window. In fact, it's an amazing way to open your eating window, because when you're in that fasted state, when you take in bone broth as the first thing, all of those rich nutrients and collagen go straight to your gut, help heal your gut, help with leaky gut, help digestive issues. And again, you can go to thebeautyandthebroth.com and use the coupon code MELANIEAVALON for 15% off. I'll put all this information in the show notes. All right, now, back to the show.

Shall we jump into everything for today?

Cynthia Thurlow: Absolutely.

Melanie Avalon: To start things off, we have a question from Ashley and the subject is "Struggling with consistency." And Ashley says, "Hi, I have been a fan and I've listened to your podcast from the start, which means I started IF back in April of 2017. I wish I could say I have done IF every single day since then. But no, it has been the struggle bus for me to do it consistently." Typically, since 2017, I IF on average four to five days a week. Some weeks are better than others when I can complete six to seven days of IF, where other weeks are harder one to two days. My window varies from 16 hours to 24 hours. Really at this point, I have been in maintenance, at times losing and gaining 5 pounds.

Now that I'm approaching my third year of IF, I've hit a roadblock in the mornings. I find myself so hungry. I usually close my window at 7pm the night before having dinner with my husband is very important to me, which is why I don't want to break my fast in the morning. It seems lately, I can only make it to 12 hours before caving on eating something some days. What I'm getting at is, do you all have tips or advice for getting through these humps? Have you ever experienced it before? I'm disappointed in myself with the inconsistency I've done with fasting over the past couple of years, which I know leads to not getting the best results. I do love the health benefits of IF and never regret it when I do fast for at least 16. It's just some days I find myself starving, and then I cave. Any recommendations you have, I would appreciate so much. Thank you."

Cynthia Thurlow: Well, Ashley, I don't know how old you are. So, I'm going to just keep this a broad response. When a woman is telling me she really struggles to get to 12, 13,14 hours, I think you need to look at your macros. Are you getting enough protein? Are the meals that you're consuming in that feeding window, are they sufficient enough calorically to be able to fill your body? Where are you on your menstrual cycle? We know the follicular phase from the day you start bleeding up until before ovulation is a time that you can get away with longer fast. And then as you transition to the luteal phase, as you're getting closer to when you're going to get your menstrual cycle, I generally recommend women fast no more than 12 or 13 hours. So, I don't know if you're in a premenstrual situation and the end stage of luteal phase and that's why you're struggling. I would really dig into if you're feeling you're a little bit weight loss resistant, how's your sleep? How are you managing your stress? Are you getting enough macros in? Are you over exercising? So, there's a lot of variables that aren't entirely clear. And I just start to see a lot of women that get into these situations where they start to feel they're not seeing the results. So, they restrict more, they're just not feeling their bodies. And I get concerned that your body may in response to not feeling it's getting enough food and is really pushing the envelope. And if you're that hungry, I would definitely recommend breaking your fast, but also understanding that there are things you can do that could potentiate your fast, but I just feel I need more information to be more specific than I already have been. How about you, Melanie?

Melanie Avalon: Yeah, I thought that was great. I love how comprehensive that there are so many potential factors going on. I would just add to it that I think a lot of people, when they're having issues with and this is what you're talking about, but a lot people when they have issues with finding the fasting hours that work for them, they think the answer is in the fasting hours, like adjusting when they're fasting. But I personally find that looking at the food intake side of things can often be potentially just as helpful or more helpful than that. Especially when people send in questions, because we have a pattern of people who send in questions.

Some people, when they're discussing fasting and their issues, they also paint a very clear picture what they're eating. Some people don't mention it at all, it doesn't even come up in the question like this one. And I don't know this is the case but that says to me that it's possible that there's not as much of a focus on what you're eating as there could be that would possibly really, really help. So, making sure that you're getting adequate protein in your eating window, which we have a question about protein coming up. And for some people, it's looking at the macros that you're eating can actually be super helpful for satiety levels. So, some people do better with the lower carb approach, and that's what really helps them tap into fat burning and not be hungry. Some people do better with a higher carb approach, and actually, those carbs are what keeps them satiated. So, I would definitely look at what you're eating, there's a lot of potential to find something there, in addition to all of the other amazing things that Cynthia brought up.

Cynthia Thurlow: Now, it's such a good point, I think we have to look at things comprehensively. When a strategy is not working, it's okay to take a break from fasting. That's the other thing that I don't hear enough people talking about, that there are times and cycles in our lives when fasting really does well for us and times when it does not and it's okay to take a break. If you feel your body's really communicating that it's not working, there are definitely ways around that.

Melanie Avalon: Yes, exactly. Especially tying into-- I was just looking at the part where she's talking about how it's some weeks that are good, and some weeks that are harder. And I really, really wonder, you were talking about with the menstrual cycle, if it does align that way. I think oftentimes people, with the menstrual cycle, they don't make the connection that there's that connection going on there.

Cynthia Thurlow: Yep. Absolutely.

Melanie Avalon: All righty. Shall we go into our next question?

Cynthia Thurlow: Absolutely, this question is from Monica. And the subject is "Third time's a charm." "I've listened to your whole podcast. I love all the information. It has seriously been so helpful in my fasting journey. Fasting has helped me overcome so much. Major hormone imbalances and an obsession over food that is totally mellowed out with the control I feel with fasting. It's wonderful and truly life changing. My question is something I never really thought could be an issue. But I found an article that said otherwise. Can a diet focused primarily around protein contribute to insulin resistance? I follow Dr. Ted Naiman who is a huge fan of protein over pretty much all else. But if you're constantly getting the spike in insulin from protein, could not have the same effect on our tolerance of insulin as sugar does. For example, a diet of low carb high protein low to moderate fat. I'd love to hear your thoughts and research. Love you guys. Seriously keep it up."

Melanie Avalon: Okay, Monica, thank you so much for your question. Really, I got so excited about researching this question, and I did a lot of research. So, I'm so excited to talk about this. So, yes, protein does release insulin. The difference between how it releases insulin compared to carbohydrates, for example, it varies. I was looking at a lot of different literature and there are charts on different foods and insulin release. And some charts will say, for example, that beef releases more insulin than carbs. But then, something else I was looking at was saying that protein requires about half of the insulin of carbs. So, it seems to be all over the place. But the point is, they both do release insulin in substantial amounts compared to fat, which is very, very minimal.

The difference with protein is it also releases a hormone called glucagon. And you can think of glucagon as the counter-regulatory hormones to insulin. So, insulin reduces blood sugar, puts sugar into storage. Glucagon actually spurs the liver to release glucose into the bloodstream. Let's say you're just eating protein, and you are nondiabetic, and you are good with your insulin regulation in general, in theory, you would eat some protein. And because you're not eating carbs with it, this is my example, the insulin would lower your blood sugar, actually, and then glucagon would actually encourage your liver to release glucose. And then, you just have a straight-line response, and you wouldn't really have those dips and swings.

All of that said, there can be some issues, potentially with, one, the fact that protein does release insulin. So, if we are eating a lot of protein constantly, we could be getting-- it could potentially encourage insulin resistance from all that insulin release, especially in the context of if you're eating a mixed diet, and you're also getting insulin released from carbs and things like that. And then, releasing the glucagon can actually also potentially be a problem, because now not only are we releasing insulin to store carbs that we might be eating with a meal, but we're also potentially releasing glucose from the liver, which might create a longer-term blood sugar insulin issue.

On top of that, the constant release of-- protein stimulates something called mTOR, which actually, it's a growth signal in the body. And there are studies on mTOR and insulin sensitivity, and too much stimulation of mTOR constantly, might also encourage insulin resistance. And then on top of that, there's a lot of studies on BCAAs. So, those are branched chain amino acids. They are some of the potential amino acids that we can get from protein. And studies are pretty consistent that high levels of those in the blood tend to correlate to insulin resistance. But the problem is, we don't know if it's chicken or egg. We don't know if high BCAAs in the blood cause insulin resistance. Or if when you are insulin resistant, your body is unable to properly get those BCAAs out of the blood. And the studies are very conflicting and inconclusive on the BCAAs.

I found a very amazing study that literally looks at this question that Monica had. It's from July 2014 and it's called, "High dietary protein intake, reducing or eliciting insulin resistance?" And it looked at all the studies to date. So again, it's a little bit older of a study, 2014. But it was looking at the studies to date that all looked at high protein intakes in different situations, and how did it affect insulin resistance and glucose control in the subjects. And I actually, because there's a lot-- It's a very long article. I actually went through and counted, because they didn't really give a graph. I just went through and counted what they actually found. I'm going to tell you because I find it very telling.

In studies of healthy people who are not obese, who are not losing weight, so this is a short-term, energy-balanced high protein diet. Basically, just going on a high protein diet for the short term, not calorie restricted, not losing weight. Three other studies found that when they compare that to a normal diet, there was no effect on insulin resistance, so we didn't see a negative effect there. And then, one study found a benefit, so that's favorable. The second category was people who are overweight also doing the same thing. Short term, they're eating a high protein diet, but they are not losing weight. One of the studies found that when they made the protein high diet with whey protein that there was a benefit. And when I say benefit, I'm talking about on insulin resistance. One study found that there was no change, so there wasn't any difference. One study found when they use casein and whey that there was no change. Another study was six weeks, it was high protein, and the protein was from legumes and whey, and they found that it actually-- the high protein decreased insulin sensitivity, but then it actually normalized the longer the people were on it. Another study in diabetics with that setup found that the high protein improved insulin sensitivity. The conclusion was that it's inconclusive.

Then, they looked at people who are on short-term diets where they were calorie restricted and high protein, and losing weight. And in those, well, they started off by saying that most weight loss diets leading to weight loss increase insulin resistance. So, if you're on a high protein diet and you lose weight, you're probably going to see a benefit in insulin sensitivity. But it's hard to know if it's from the protein or if it's from the weight loss. They found that two studies compared high protein diets to other calorie-restricted diets for weight loss and the high protein diets had more of a benefit. One study found, comparing it to a control, so not to a calorie-restricted diet, it found a benefit. One study found that the high protein diet did not have as beneficial of an effect on Homa IR, which is a good marker of insulin sensitivity, but it did have a better effect on beta cell function and the pancreas. So, that's a little bit confusing. And then, two studies found that it was the same benefit. And then, one study found that it was looking at high protein versus high carb in a calorie-restricted situation, and the high carb was superior.

Last category, I'm almost done. And then, the section looking at long-term intake of high protein diets, one study looked at six months of people who are healthy on high protein diets. And they found that those on the higher protein diets had higher insulin resistance and more glucose issues. A collection of observational studies on diabetes found that high protein diets led to more issues. But then The Nurses' Health Study looked at low carb high protein diets and they did not find those issues. And then they actually did find that long-term intake of high protein from vegetable protein actually benefited insulin resistance. And then, there was another meta-analysis that they referenced. And that looked at 15 randomized control trials of more than 12 months on the long-term effects of diets high in protein. And it showed neither a positive nor a negative effect on glycemic control compared to diet low in protein in both healthy and insulin-resistant subjects.

Okay, sorry that that was so much information. But basically, there's been a lot of studies looking at this issue. Like I just went through all of those, the effects seem to be pretty mixed. It's interesting, because the study I was referencing, they concluded that high-protein diets and insulin action are not univocal, which means unambiguous. So basically, it is ambiguous. And that insulin sensitivity seems to have a beneficial effect in high-protein diets when people are overweight or insulin resistant, and they are losing weight. In the short term, having a high protein diet doesn't seem to really affect insulin action. But in the long term, there might be a-- or they say it seems to be deleterious when the intake is prolonged. And that this goes along with seeing high plasma BCAA levels in the blood, like I was talking about. Their ultimate conclusion is that in the long term, increased insulin secretion and consequent hyperinsulinemia might lead to reduced hepatic insulin sensitivity. Increased hepatic glucose output results in a decrease glucose control, although a direct effect in insulin action and insulin sensitive tissues can also have a role.

My thoughts stepping away from all of this is that yes, if you are doing high protein-- well, especially if you're doing high protein in the context of energy-toxic diet, a diet with too much energy in the long term, I think definitely can encourage an issue, contribute to an issue. If you're eating protein constantly 24/7, it could have those issues with mTOR. It could have basically all of these issues. In the context of weight loss, I don't think most people would need to worry about this at all. In maintenance as well. I'm not sure but I do feel for people who are doing intermittent fasting, we're getting that period during the fast of low insulin. We're getting that period of low mTOR. I think it's crucial that we get adequate if not high protein when we do eat. So basically, I really think that the issue here is energy toxicity, not protein completely. That was a really long answer. Cynthia, do you have thoughts?

Cynthia Thurlow: No, I am in awe of the research that you did. My clinical context, just thinking thoughtfully about this question is, I'm 100% in agreement that the energy toxicity, meaning you're eating too much food, is really the issue. Now, when we look at the bulk of the population, we know 92-93% is metabolically inflexible and unhealthy, it is likely not too much protein, that's the issue. It's the overall there's just too much caloric or the macros are imbalanced. It's overwhelming the body's storage sites. And it is less about protein, and more about all of the other factors. Most people, perhaps not our listeners, but most individuals here in the United States are drinking caloric beverages all day long. They're eating anywhere from 6 to 10 times a day. And when you're really looking at the degree of meal frequency, the average American is doing-- average westernized person combined with those beverages, I think that is a greater issue. And for them, if they suddenly go high protein, and they still have all these other behaviors that I've identified, then that can become a larger issue.

And it's interesting, Ted Naiman, I've interviewed and I'm very aligned with him on many, many things. And he has this amazing book that is only an electronic book, which means I don't own it, because I like having physical books for most of my things that I want to reference. But he posts a lot of fantastic content on Twitter and YouTube. And it's a great resource. And he talks about how a certain amount of protein and fats will shut that satiety, you'll hit those satiety hormones that you just physically can't consume more food. And I think that's an important distinction along with everything else that you said. But I'm so grateful you did all that amazing research. I'm just going to speak to it as a clinician, and I think it has everything to do with an overconsumption of calories, in general, that is creating this toxicity and this degree of lack of metabolic flexibility and insulin resistance.

Melanie Avalon: Yeah, what you just said is basically exactly how I feel. And I think the nuance as well is that, so say we are in energy toxicity situation on a low protein diet, the energy toxicity is primarily coming from carbs and fat. Just stepping aside, in general, energy toxicity is, I think, the issue. If you have low protein, the factor that you don't have going on in that situation, is that you're not getting that glucagon stimulation, that would be prompting the liver to be constantly also releasing glucose from the liver, which would be further exacerbating issues as well as the potential buildup of those amino acids in the bloodstream. Compared to when you do have the protein, you've got that secondary issue going on.

And I did want to throw in, because I left out one other thing because that was 2014. There was actually a 2020 meta-analysis, and it looked at 12 articles with 13 studies including patients with diabetes, and they actually concluded that a high protein diet does not significantly improve glycemic control and blood pressure. They didn't say that it hurt it, they just said it doesn't improve it. But it can lower LDL, TC, TG and Homa IR levels in patients with type 2 diabetes. Further studies are needed to clarify the effects of high protein diet and glycemic control, insulin resistance and blood pressure control and type 2 diabetes. I just want to throw that one in there because I left it out.

But I'm glad you brought up Ted Naiman, I love him, we can put links to the episodes that we've had with him. I also really love Marty Kendall. He had a really good article on the glucagon aspect of this that I was reading, and he actually referenced Ted Naiman in that study as well. All that to say I agree with-- what you just said is what I agree with that. I think the issue is the energy toxicity.

Cynthia Thurlow: No, it definitely makes sense.

Melanie Avalon: Okay, I don't know if Monica expected that long of an answer. [Cynthia laughs] All right, we have a question from Jessica, and the subject is "Menopause, HRT, etc." Jessica says, "Hi, I love this podcast and I learned so much about IF. My doctor advised me to start IF a month ago when she put me on HRT. I'm 37 and still breastfeeding my daughter aged one, but I'm also postmenopausal as my ovaries were removed in December. My doctor advised HRT because my estrogen was unsurprisingly very low, and my DHEA and testosterone were very high. I've been doing IF starting at 16:8 a month ago, and now usually doing 18:6 and sometimes 20:4. I have not lost a single pound. My clothes do not fit differently. I am at my highest weight ever and getting so discouraged every time I step on the scale.

I have now been on low doses of bioidentical estrogen and progesterone for a month while doing IF. And although I feel some benefits, it's helped some digestive issues. I need the scale to move in order to feel my health is improving. Losing even a few pounds would give me hope, but it is just not happening. How long do I stick with this before it's time to admit it is not working for me? I'm also a vegetarian, but I sometimes eat the occasional fish. I'm reading that the research on IF for women is mixed, and it may have negative consequences for postmenopausal women. Is it possible this just isn’t for me? I hope that's not the case. Because this is the only diet, I've ever tried that I felt was sustainable. Thanks in advance, keep up the good work."

Cynthia Thurlow: Ah, Jessica, you have a lot going on. Oh, my goodness. You're still a very young woman, and we know women that have their ovaries removed before the age of 42 are at greater risk for developing cognitive issues. So, I'm grateful that your doctor is being very proactive and considering hormone replacement therapy. My concern is, and I'm just going to start from the top, I'm not in agreement with women breastfeeding or being pregnant and fasting. You're wanting to lose fat, but your body is still feeding a baby. And I'm sure if she's one, she's probably eating a lot of solids. And so, her breastfeeding might be brief and just a few times a day. But just something to think about in the position that you're in, you're giving your body mixed signals. You want it to lose fat, but you still want to be able to sustain being able to breastfeed, and I find for most women while they're breastfeeding, it's harder for them to lose body fat. So, that's number one. Since you're so young, I'm curious to know why your ovaries were removed at such a young age because that's very significant.

You're mentioning that your testosterone was high. The question is why. Did you have polycystic ovarian syndrome? When I start thinking about the reasons why women can have high testosterone, that's almost always the first thing I think about. Does your husband take supplemental testosterone? Probably not, because you're both very young, but you can sometimes get exogenous exposure that way. Just in thinking about the bioidentical hormones, it could be a combination of too much stress on the body, breastfeeding, fasting. Going into menopause is a big adjustment, and you have surgical menopause, meaning the average age of a woman in the United States to go through menopause is 51. You're 37. So, you're very, very young. And so, from my perspective, it's trying to get a sense from what you've shared as to what could be going on.

The other thing that I get concerned about is most vegetarians in my clinical experience consume too many carbohydrates, not enough protein. And you really have to work at that very diligently. If you're eating very limited, animal-based protein, hopefully, you're eating some eggs, which will make that easier. But the challenge is, if you're trying to fuel weight loss and you are vegetarian, you're very likely overconsuming carbohydrates. And then, you're also breastfeeding, and your body needs a little bit of extra fuel to be able to make that happen. I wrote a whole book about women and fasting.

And I generally will suggest the women check that out. There is research on postmenopausal women. And I find the women that generally do the best are the women who have stable hormones, meaning, when you're no longer menstruating, your hormone levels are stable, much more stable day to day, week to week than a woman who's still in peak fertile years, or even a perimenopausal woman-- there's a lot of good research that women can do very well in menopause, with intermittent fasting, provided that they're sleeping high quality sleep, they're managing their stress. And as a new mom, it's not unstressful to have a little baby at home and then stressing about trying to lose weight. I mean, those are two big things, eating anti-inflammatory nutrition, and really thinking about, things that fuel insulin sensitivity. And I think about walking after a meal, and lifting weights and things like that.

So, there's a lot to unpack here, I would give it more time. If you're breastfeeding, you need to give yourself some time. I used to always say six months was always that time period that I felt most of my patients got to a point where they were starting to see some weight loss, 12 to 18 months. And if you're still breastfeeding, it's going to make it a whole lot harder to lose weight. So, please give yourself some grace. Make sure you're getting your hormones tested, make sure you've got a DUTCH as well as serum blood labs. I think that would be very helpful. And the other question that dovetails into that is why is your testosterone so high? Did you have PCOS? What was the precipitant for removing your ovaries? That's a pretty drastic surgery for such a young woman. I would imagine there's a good reason, but just not a reason that's entirely clear to me right now. What do you think, Melanie?

Melanie Avalon: Well, I thought that was absolutely amazing and comprehensive. That was one of the takeaways I really took away from reading your book, Intermittent Fasting Transformation, was the difference with fasting in pre-menopausal and postmenopausal women and where do you think this idea-- because people ask this a lot or say this, that there are negative consequences for postmenopausal. But have you seen that? I mean, would the concern be I guess sarcopenia, not getting enough protein? I'm just wondering where this idea is coming from.

Cynthia Thurlow: I think there's a degree of fear mongering This is why I'm not a fan of OMAD. And that may upset people but I'm going to just say it, you just can't get your macros in. And once you're going through perimenopause, and menopause, physiologically, we are just much more at risk for muscle loss and the way that you need to think about how important and-- Gabrielle Lyon has been on your podcast, she has been on my podcast, she's a really close friend. I tell her all the time that her work completely changed everything that I talked about. But you want to think about muscles as a glucose reservoir. They're critically important for being metabolically healthy. And as you are losing muscle, and that's being replaced by fat--

I always talk about the filet, which is young muscle. Melanie has young muscle Melanie, so Melanie is a big fillet. And I'm 51, so my muscles, if I don't work really hard, are going to look like a ribeye and a ribeye is delicious. But we want to be a filet for as long as we can be. And I'm not talking about aesthetics. I'm talking about musculature, it's so important. And the concern I get is when postmenopausal women, perimenopausal women are just bucking this trend of, "I'm only hungry for one meal a day and that's all I eat," I just have to remind them, one of the reasons why you're not more-hungry, is you're starting to lose lean muscle mass. And as Gabrielle says, "You are not overfed, you're undermuscled." So, it's really important to understand that I think a lot of the concerns and fear about menopausal women is largely a byproduct of this concern that they are going to lose muscle mass if they're not eating at least two meals a day, we're not talking about 6 meals a day, or 10 meals a day, which I eat two meals a day so that you can get enough protein in your diet.

The other thing that I think is important note is that we're de facto less tolerant of stress as we head into perimenopause and menopause. It's a byproduct of the loss of progesterone from our ovaries, as our adrenals are stepping in to help support our body, we are just not as stress resilient. That doesn't mean we can't manage stress, we don't manage it as well. And so, I think on a lot of levels, there's this concern that if women head into their 40s, and 50s and beyond, and they're overfasting, overrestricting, not exercising or doing the wrong types of exercise, that they can put themselves at risk for a lot of inflammation, a lot of bodily stress. But I sometimes feel menopausal women have an easier time because they don't have to deal with the factors of a menstrual cycle and follicular phase and luteal phase. I would say men and menopausal women can sometimes have the easiest time fasting of all because they don't have to worry about this biology of procreation and conception and fertility and infertility that younger women have to worry about. But I do think it's a huge problem.

In fact, I'm not going to say this person's name, but there's a person who just had a book come out and they love to fearmonger about women and fasting. And I've had to have this discussion quite a bit. And I don't want anyone to perceive that. If you're sleeping well and you're dialing in on your nutrition and you're managing your stress and you're fasting for your cycle and you're not overexercising, that fasting can't be a part of or eating less often, can't be part of your strategies that you use to feel good about navigating whatever stage of life you're in. I think a lot of that comes from well-meaning people who don't really know what's going on. That's my feeling.

Melanie Avalon: I cannot agree more. It's actually similar or relates to the findings speaking of what you're talking about earlier with protein, on protein and longevity. There are so many people, researchers and such like Dr. Valter Longo, who I've had on the show-- he's actually been on this show, and he's been on the biohacking podcast, but he and people in his sphere are very much pro low protein for longevity up until, I think, age 60. And then, you need higher protein. So, I think that does relate to everything Cynthia was talking about, about when you are at that older age and the more difficulty it is to create and maintain muscle, women in particular really need the higher protein when they're older. I don't think that should be lumped in with the fasting, which I think can happen. It just might be like Cynthia was saying that you need a longer window to get in that adequate protein intake if you're not like me where I eat all the protein.

Cynthia Thurlow: The unicorn, but I think that's one of the reasons why I love podcasting with you as we really speak to such a wide age range of women. And I think that's really important because if we were both 50 somethings or if we're both 30 somethings, we would not necessarily totally represent our demographic, right?

Melanie Avalon: Yeah, exactly. It's funny before I even started the show, way back, I remember brainstorming about what did I want the show to look like. And at first, I was like "Oh, I want to cohost with somebody like my age. And it'll be two girls having wine night, two young people." But when I met Jen, I was "Oh, this is actually much more appropriate," because it's just so much helpful to give the broad perspective, and then it's even better when we're friends as well. It's all the good things.

Cynthia Thurlow: Exactly. And I think it's important for people to understand that there's a genuine camaraderie here. So, we can both benefit from our own experiences. My kids know who Melanie is. When we talk about Melanie's eating window, and her sleeping habits and how different we both are, and that's the beauty of it is that there's listeners who very likely-- there might be someone who has a long, evening eating window and stays up really late-- And I think, it's only when I was traveling in Europe that we overlapped at the same time, like we were awake for the longest stretch of time at the same time. I was like, "This is cool."

Melanie Avalon: Yeah. It's funny, I get DMs from people because I do think my approach is very rare. But there are? I know you guys are out there who actually do it very similar to me, and quite a few people DM me, and they're just like, "Thank you for letting me know I'm not alone in my crazy late night, feast every night." So, we are out there, but it definitely doesn't work for everybody, that is for sure.

Friends, I'm about to tell you how you can get 50% off a product that has truly changed my life. Do you experience stress, or anxiety, or chronic pain? Do you have trouble sleeping at least once a week? If you do, trust me, you are not alone. I personally have explored so many avenues for how to have a healthy relationship with stress and finding the world of CBD oil has been absolutely incredible for that. After doing more and more research, I've realized just how incredible the health benefits of CBD are. CBD regulates your cannabinoid system, kind of like an adaptogen, making you feel better naturally. It's not addictive, it's not a crutch. Basically, it's just helping your body function better when it comes to stress, anxiety, pain, and sleeplessness. I take it daily for my mood and the effects are profound. In fact, I even got robbed last year and I went from crying with stress and anxiety to taking some Feals and laughing. I said to my mom, "Mom, see how effective this is?"

Due to all of its health benefits, we knew we wanted to partner with a CBD company for the podcast. But I have very stringent criteria. You guys know this. So many brands approached us, and I kept just saying no because nothing fit all of my criteria. I wanted a CBD oil that was full spectrum, tested for purity, organic, made with MCT oil as the carrier, and that I actually experienced benefits from. That's a pretty tall order to fill. We said no to a lot of brands, and then Feals came along, and it was meant to be. I personally tried it out and started seeing massive effects on my sleep and stress. Feals is so easy to take. You can just put a few drops under your tongue, and you'll feel the difference within minutes. I truly do feel it within minutes. Of course, it is important to remember that CBD works differently for everybody based on your own unique cannabinoid system, so you might need to work to find your perfect dose. Experiment over the course of a week or so, and you may find that you need more or less depending on the effects that you're looking for. 

I'm also super grateful because they have an incredible offer for our audience. You can start feeling better with Feals. Become a member today by going to feals.com/ifpodcast and you'll get 50% off your first order with free shipping. That's feals.com/ifpodcast to become a member and get 50% automatically taken off your first order with free shipping. feals.com/ifpodcast. When you get that offer, you'll be joining the Feals community and you'll get Feals delivered directly to your doorstep every month. You'll save money on every order and of course, you can pause or cancel anytime. So, definitely try it out for the first month with our code for 50% off and see how it works for you. We'll put all this information in the show notes. All right, now, back to the show.

All right. Shall we answer one more question?

Cynthia Thurlow: Absolutely. This is Mary, "Prescription meds breaking fast." "Hello, I've just begun IF." So, her eating is either 19:5 for two days or 20:4. "I've long abstained from between meal eating, so this was a fairly easy transition for me. I am determined to have clean fast. However, I saw a comment today on Facebook regarding melatonin, and the word was that it does contain sugar, so realistically breaks the fast. I have a long list of prescription meds. So far, I've looked at four that are must-haves, and they all have that same ingredient. My feeding window is 12:30 to 4:30. I can take my evening pills right at 4:30 and some of my AM pills right at 12:30. But some must be taken 12 hours apart. My question is, if I take the must-haves when I wake up, does that wreck my clean fast? Eager to hear. I want to do this right. Thank you for your time, Mary."

Melanie Avalon: All right, Mary, thank you so much for your question. So, something to clarify, because I can see how this can happen. You talked about how you heard melatonin, and it contains sugar, and so, it breaks the fast. And maybe this goes without saying but with something like melatonin, which is not a prescription, there are many brands of melatonin, and they do not all contain sugar. So, melatonin does not equal sugar, does not require sugar to be taken. For melatonin, for example, you can find a melatonin that is fast friendly. We love melatonin from MD Logic for example. So definitely check them out. You can use the codes, MELANIEAVALON or CYNTHIA, to get a discount on that I know Cynthia in particular has really benefited from that melatonin. So that's supplements like non-prescriptive supplements, you can usually find a version that is clean, fast friendly, especially when it's not a prescription because there's normally lots of versions of it.

When it comes to prescription medications, if you have to be taking your prescription medications, you have to be taking your prescription medications. Some of them might contain ingredients that break the fast like she has found out. I'd be curious what she found in it that was-- I'm wondering what the sugar ingredient that she's thinking. I'm wondering if it's something-- I'm just wondering what it is exactly. There are a few things. One, I think a lot of people don't realize this, but this is actually an option. You can actually get a lot of prescription medications compounded, I actually do. If you have a compounding pharmacy that you like and can work with, they can often make compounded versions of your medication with the exact fillers that you want, or even no fillers. It's not always a possibility. And sometimes if it's a possibility, it's extremely expensive, so then it's not really a possibility. But for some of the medications, it is a possibility. I've done that in the past for things.

If that's not the case and you need to go with the traditional prescription form, there are a lot of generic versions of a lot of prescription medications. You can look up the prescription and you can try to find the one that is the most "fast friendly." It does take a little bit of detective work, I'm thinking of little detective emoji in my head. But that is an option. And you can talk with your doctor if you want a specific generic version prescribed. All of that said, if you need to take the prescription medication and you cannot find a clean, fast friendly and you cannot get it compounded. It's okay, [chuckles] you have to take your medications when you have to take them. It's not like this is actual food. I'm not giving a greenlight to taking in minute amounts of sugar or anything that in general. But when it comes to medication, you have to take your medication. Don't stress about it. It will be very minimal, if anything. Those are my thoughts on medication. Cynthia?

Cynthia Thurlow: The irony is I have 45 cohort going right now, and we had our first group call. And that was the first question that I was asked today. And here's the thing, if you have to take a medication, you have to take a medication, period. There should be no stress about, does it break your fast, does it not breaks your fast? I'm always very transparent talk about the fact I take now compounded thyroid medicine, and I take that during my fasting window and that does not break my fast. Now, the issue with generics, and people may not know this, but you can get these tremendous variances. There are generics you can get sometimes like 20% variants. As an example, before I was taking compounded progesterone, I would sometimes wonder why some nights I'd sleep really well and some nights I wouldn't. My functional med doc actually pointed out, "Well, you realize, you probably remember this but for generic medications, even though it's a bioidentical, you still have this variance." And so, I would just state that-- sometimes the trade medications that you pay a little more for-- and by no means am I telling people to break their budget to do this, but if you feel you don't do as well on a generic, just understand it can be 20% different than the trade product. I had a lot of women, especially my thyroid patients, that would tell me they would not take generic Synthroid. They only took regular Synthroid because they had intolerances. I had patients on antihypertensive, so medications for their blood pressure, same thing. We're all individuals but please do not let the concern about breaking a clean fast be the reason why you perceive that you have to do all these different things to me make this work.

Now, there should be no sugar in melatonin. And if there is, then I would definitely look for another option. I speak very openly that the two options I use are Sandman, that's a whole other special conversation about that supplement. But the MD Logic melatonin is more efficacious, meaning it's stronger than the Designs for Health product I'd been using for several years, and I even used on myself as well as my patients. One capsule of MD logic was equivalent to three of the Designs for Health sustained release. To give you an idea, it's very cost effective, and I'm not sharing that to sell everyone on that brand, but just to share that's what works for me. Sandman is a per rectal melatonin, but it's also largely cost prohibitive for the average person, I probably use it twice a month. But with that being said, please don't let that be a concern. Now, if your supplement has sugar in it-- there was a woman in my other group who had a product that had 40 grams of sugar and 30 grams of carbs. And I was like, "First of all, you need to throw that in the garbage."

Melanie Avalon: In what? Supplement?

Cynthia Thurlow: Yeah, there were gummies. And I said, "Okay, well, a gummy is going to be full of sugar, because it's going to be soft and--" Anyway, a whole separate conversation. But the point of what I'm sharing is, we want to try to find the cleanest options that are out there. Things without gluten and dairy and grains and soy, just be diligent when you're selecting supplements to try to find really high-quality products. Yeah, that's my ramp. But please don't let concerns about your medication breaking your fast keep you from taking medications that you are prescribed and that you need.

Melanie Avalon: That's so fascinating. I know you said you've seen it in hypertensive medications as well. Do you find it is more the hormonal supplements where that's an issue or is it just across the board?

Cynthia Thurlow: Well, it's interesting, because many years ago, when I was taking oral contraceptives, I remember when I was a student at Hopkins, I had this one brand of oral contraceptives. And I also had mild phenotype PCOS, I had no idea why I had these crazy wild periods. Well, it's because I had PCOS and that's why I initially went on the pill. And the student health center was "Oh, we've got the generic version of what you're taking." I went on the generic and gained 10 pounds. And I remember them saying, "Oh, there's nothing different in this." And then, I remember talking to my faculty, and they were like generic is exactly that. They only have to have 80% of the formulation the same.

Melanie Avalon: Legally?

Cynthia Thurlow: Yeah, and you can have different fillers. There's lots of things that happen with these medications that I used to say-- Some people do fine with the generics, let me be clear, there's nothing wrong with generics. But I think there are definitely people who are much more sensitive to additional fillers and different formulations of medications. And so, that's where I think it's important to just have the conversation. If you're doing fine on what you're taking, great. If you're not, investigate what other options are available.

Melanie Avalon: Wow. It's interesting, because I had sort of vaguely wondered that in general about the generics, but I hadn't really looked into it.

Cynthia Thurlow: Yeah, up to 20%.

Melanie Avalon: Um, it's concerning.

Cynthia Thurlow: Yeah.

Melanie Avalon: Well, thank you. That's very valuable information. Thank you for sharing.

Cynthia Thurlow: You're welcome. It'd be a little depressing for everyone to hear. But the irony is one of my pharmacist friends and one of my doctor friends just happened to say that to me the other day, and I was like "Oh, my gosh, I forgot that. It's so true. It makes complete sense."

Melanie Avalon: Wow, wow, wow. Well, thank you.

Cynthia Thurlow: You're welcome.

Melanie Avalon: For listeners, if you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. The show notes for today's episode, which are going to have a lot of links, as well as a full transcript, will be @ifpodcast.com/episode286. And then, you can get all the stuff that we like at ifpodcast.com/stuffwelike. And you can follow us on Instagram. We are @ifpodcast. I am @melanieavalon, and Cynthia is @cynthia_thurlow_. All right. Well, this has been absolutely wonderful. And I will talk to you next week.

Cynthia Thurlow: It sounds good.

Melanie Avalon: Bye.

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman. Editing by Podcast Doctors. Show notes and artwork by Brianna Joyner. Transcripts by SpeechDocs. And original theme composed by Leland Cox and recomposed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription]

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Aug 14

Episode 278: Food Rules, Fortified Foods, Synthetic Vitamins, Weight Loss Timelines, Constipation, Magnesium, Bitter Foods, Bile, And More!

Intermittent Fasting

Welcome to Episode 278 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

BUTCHERBOX: Grass-Fed Beef, Organic Chicken, Heritage Pork, Wild-Caught Seafood: Nutrient-Rich, Raised Sustainably The Way Nature Intended, And Shipped Straight To Your Door! For A Limited Time Go To Butcherbox.com/ifpodcast And Get Free BACON For LIFE plus $20 off each box for the first 5 months of your membership!

BEAUTY AND THE BROTH: Support Your Health With Delicious USDA Organic Beauty & The Broth Bone Broth! It's Shelf Stable With No Preservatives, And No Salt Added. Choose Grass Fed, Grass Finished Beef, Or Free Range, Antibiotic And Hormone-Free Chicken, or Their NEW Organic Vegan Mushroom Broth Concentrate! The Concentrated Packets Are 8x Stronger Than Any Cup Of Broth: Simply Reconstitute With 8 Ounces Of Hot Water. They’re Convenient To Take Anywhere On The Go, Especially Travel! Go To melanieavalon.com/broth To Get 15% Off Any Order With The Code MelanieAvalon!

FEALS: Feals Makes CBD Oil Which Satisfies ALL Of Melanie's Stringent Criteria: It's Premium, Full Spectrum, Organic, Tested, Pure CBD In MCT Oil! It's Delivered Directly To Your Doorstep. CBD Supports The Body's Natural Cannabinoid System, And Can Address An Array Of Issues, From Sleep To Stress To Chronic Pain, And More! Go To feals.com/ifpodcast To Become A Member And Get 50% Off Your First Order, With Free Shipping!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get Free BACON For LIFE Plus $20 Off Each Box For The First 5 Months Of Your Membership!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

The End of Craving: Recovering the Lost Wisdom of Eating Well
Steak: One Man's Search for the World's Tastiest Piece of Beef
The Dorito Effect: The Surprising New Truth About Food and Flavor
(Mark Schatzker)

BEAUTY AND THE BROTH: Go To melanieavalon.com/broth To Get 15% Off Any Order With The Code MelanieAvalon!

Listener Q&A: Violet - IF Timeline

FEALS: Go To feals.com/ifpodcast To Become A Member And Get 50% Off Your First Order, With Free Shipping!

Listener Q&A: Liv - 1-2 hour window, constipation, when everything balances out?

AvalonX Magnesium 8: Get Melanie’s Broad Spectrum Complex Featuring 8 Forms Of Magnesium, To Support Stress, Muscle Recovery, Cardiovascular Health, GI Motility, Blood Sugar Control, Mood, Sleep, And More! Tested For Purity & Potency. No Toxic Fillers. Glass Bottle.

Episode 276: Magnesium Benefits, Supplementing A Whole Foods Diet, Medication Interaction, Stress and Depletion, Absorption, Dosing, and Effectiveness, And More!

She-ology: The Definitive Guide to Women's Intimate Health. Period. (Sherry A. Ross, MD)

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 278 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time and get ready for The Intermittent Fasting Podcast.

Hi, friends. I'm about to tell you how you can get sugar free, nitrate free, heritage breed bacon for life, plus up to $100 off. Yes, free bacon for life plus up to $100 off. We are so honored to be sponsored by ButcherBox. They make it so, so easy to get high-quality humanely raised meat that you can trust. They deliver 100% grass-fed, grass-finished beef, free range organic chicken, heritage breed pork that's really hard to find by the way, and wild caught sustainable and responsible seafood shipped directly to your door. When you become a member, you're joining a community focused on doing what's better for everyone. That includes caring about the lives of animals, the livelihoods of farmers, treating our planet with respect, and enjoying deliciously better meals together. There is a lot of confusion out there when it comes to transparency, regarding grazing practices, what is actually in our food, how animals are being treated. I did so much research on ButcherBox. You can actually check out my blog post all about it at melanieavalon.com/butcherbox. But I am so grateful for all of the information that I learned about their company. All of their beef is 100% grass fed and grass finished. That's really hard to find. They work personally with all the farmers to truly support the regenerative agriculture system. I also did an interview with Robb Wolf on my show, The Melanie Avalon Biohacking Podcast, all about the massive importance of supporting regenerative agriculture for the sustainability of not only ourselves, but the planet. This is so important to me. I'll put a link to that in the show notes.

If you recently saw a documentary on Netflix called Seaspiracy, you might be a little bit nervous about eating seafood. Now, I understand why ButcherBox makes it so, so clear and important about how they work with the seafood industry. Everything is checked for transparency, for quality, and for sustainable raising practices. You want their seafood. The value is incredible, the average cost is actually less than $6 per meal, and it's so easy. Everything ships directly to your door. I am a huge steak lover. Every time I go to a restaurant, I usually order the steak. Oh, my goodness, the ButcherBox steaks are amazing. I remember the first time I had one and I just thought, “This is honestly one of the best steaks I've ever had in my entire life.” On top of that, did you know that the fatty acid profile of grass-fed, grass-finished steaks is much healthier for you than conventional steaks. And their bacon, for example is from pastured pork, and sugar and nitrate free. How hard is that to find? I'm super excited, because ButcherBox’ bacon for life is back and it's even better, because for a limited time, ButcherBox is giving you $20 off each box for the first five months of your membership. That's free bacon for life and up to $100 off. Just go to butcherbox.com/ifpodcast. That's butcherbox.com/ifpodcast to get one pack of bacon for free in every box for the rest of your life, as well as $20 off each box for the first five months of your membership. butcherbox.com/ifpodcast. And we'll put all this information in the show notes.

And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense, because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly one of the most influential factors in weight gain? It's not your food and it's not fasting, it's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup maybe playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That's because ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last for years. 

Conventional lipstick, for example, often tests high in lead and the half-life of lead is up to 30 years. That means when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so, you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life. And their makeup is amazing. Check out my Instagram to see what it looks like. Tina Fey, even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well.

And lastly, if you're thinking of making Clean Beauty and Safe Skincare, a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show.

Melanie Avalon: Hi, everybody and welcome. This is Episode number 278 of The Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with, Cynthia Thurlow.

Cynthia Thurlow: Hello, my friend. 

Melanie Avalon: Well, first of all, happy, early birthday to you.

Cynthia Thurlow: Thank you. Yeah, it's been a good year. I feel I'm not one of those people who gets freaked out or weirded out about birthdays. In fact, I just look at it as, how much growth have I had in the past year? And I think it's been a pretty amazing year. So, I'm very grateful. But thank you. 

Melanie Avalon: Yeah, it's definitely a really nice milestone or it's a nice moment to reflect on how far you've come to quantify time.

Cynthia Thurlow: Exactly. There's been a lot of growth in a lot of different areas. I feel I'm in a good, healthy place.

Melanie Avalon: So, question for you that will apply to all of the listeners. Well, I guess, I need to know more about-- Okay, so, your everyday dietary choices that you follow, personally for you, do you do gluten free, dairy free? Do you have food rules?

Cynthia Thurlow: I do. I've been gluten free for 10 years and that put an autoimmune issue that I have into remission. And I've been dedicated dairy and almost 100% grain free. Occasionally, I may have a little bit of rice, but I'm dedicated to no gluten, no dairy, and almost 100% no grains. And I'm heavily meat focused. I would say the last three years, I've been much more diligent eating a lot less fish and chicken and really expanding my repertoire of meat and then a lot of vegetables. I like vegetables genuinely.

Melanie Avalon: And how do you exist within the Whole Foods versus processed foods paradigm?

Cynthia Thurlow: I would say, on occasion, I will have a cracker. I like Hu crackers. They're super expensive. So, it just reminds me that I really do portion out my portions. I'm a big aficionado of dark chocolate. So, clearly, that's processed. I think it's a lot of our perspectives on nutrition really need to be based on what are our goals, what fuels our body makes us feel good. And I think that's highly individual. I would say, obviously, my electrolytes are processed to an extent. Electrolytes are a large part of my world. I realize when I travel, I'm like, “Oh my gosh, my electrolytes.” I feel so much better with them. But normally, I tend to eat a less processed diet. I'm not perfect. I'm not like I’m living off the land, and I have my own cow, and I process it, and I only eat what I have in my yard. No, that's not the way I live my life. But I do endeavor to eat as minimal processed food as I can within a realistic framework. Because I can honestly tell you after spending a weekend in a very rural part of my state, I do realize that there are conveniences that are important for me, and my sanity and my family sanity, and I don't have a problem with them. If I'm buying something processed per se, I'm buying the cleanest version of that product possible within the context of what's important to me. Like, no seed oils, no high fructose corn syrup. I'm thinking more about my teenagers and it's getting more challenging as they get older to be able to navigate that realm and still ensure that they're having some fun foods.

Melanie Avalon: Well, first of all, I think that's a really healthy approach [laughs] that I would encourage for everybody. There're two paths I want to take right now. One is, because I want to talk about a book that I just finished that relates to all of this. But the reason I was asking you all of those questions, you might see this coming. When you have something celebratory like your birthday, is there some sort of food indulgence that you treat yourself to or how does that go?

Cynthia Thurlow: In our new city, everyone knows I have these mental food rules that are important to me. We've struggled to find a restaurant that meets all of those needs. The kids and my husband decided, “We're going to just make a really nice dinner.” We have steak and I love shishito peppers. I'm obsessed with them. And my husband will grill them for me. But my treat is not alcohol. My treat is for making a gluten free brownie and I'm going to savor and enjoy every single bite of said brownie. My kids just made, I think, they even put chocolate chips in it. And then there is a dairy free, junk free, it's like Cool Whip, but it's not Cool Whip. It doesn't have all the junky emulsifiers and whatever is in Cool Whip that I try to avoid. There's a product that's out there that's clean. It's made with coconut milk. And so, I'm going to put that on top of my brownie probably with some blueberries and I'm going to savor every single bite.

I generally avoid eating products that have flours in that [unintelligible [00:12:38] flour. And then because it really has a detrimental impact on my blood sugar, but I'm also going to take a walk after I eat my dinner. So, [laughs] that's usually where I will enjoy myself. I'll have a dessert for my birthday. I believe fervently that all of us, when we have a celebration, we should enjoy ourselves that we will build into our week, or day, or what have you ways to kind of buffer that indulgence.

Melanie Avalon: I'm so glad you said that, because that relates to the book topic. But first of all, do you know the name of that coconut milk, Cool Whip? Because listeners might want to buy it. 

Cynthia Thurlow: It's called Cocowhip. It changed my life. It's better than Cool Whip, but to me, I don't eat ice cream. Okay, so, it has filtered water, coconut oil, tapioca syrup, cane sugar, pea protein. Okay. It's not the cleanest thing in the world, but it is certainly better than-- There's one that's even cleaner than this one that they have it my Whole Foods, but that's the brand.

Melanie Avalon: Okay, awesome. Yeah, I'm all about finding the things that work for individuals. Awesome. So, we'll put links to everything in the show notes.

Cynthia Thurlow: Sounds like a crazy person. I can't remember the name, but it makes me feel I'm having ice cream and I'm not and it's delicious. My kids think I'm a wackadoodle. They're like, “Just have the ice cream, mama.” I'm like, “No,” because dairy does not agree with me. It's just an unpleasant interaction with my digestive system.

Melanie Avalon: The book, I kept texting you about this book and I finally finished it last night. It is blowing my mind. 

Cynthia Thurlow: Really?

Melanie Avalon: Yes. So much. I'm going to read his other two books. But listeners might be familiar because Gin would always mention this book called The Dorito Effect. It's not The Dorito Effect, but it's his newest book. The author is Mark, I think it's Schatzker. It's spelled interestingly. The book is called The End of Craving. Okay, there's so much in this book. I was just going to read it for the interview, but I just think it's so amazing that I'm going to read his other two books, The Dorito Effect. And he has a book called Steak. The subtitle is, One Man's Search for the World's Tastiest Piece of Beef. Apparently, it's like a travel food thing, where he went all over and learned about the different raising practices of cows and the different steaks, and he talks a lot about steaks. So, I'm can’t read that. In The End of Craving, he talks about a lot of stuff. But basically, the main thesis is that, when we started fortifying foods and adding additives, and flavorings, and all these things, but all of that is what led to the obesity epidemic. And so, there's a lot of different topics that he discusses. But I'll just give like two of them, for example. With the fortification of foods, this is so crazy. He talks about the pellagra epidemic. Are you familiar with that that happened?

Cynthia Thurlow: Vaguely. 

Melanie Avalon: I actually want to interview Bill Schindler, who wrote a book called Eat Like a Human. He talks about it, too. But basically, there was this mysterious disease called pellagra and it killed so many people. And they didn't know what caused it. People thought it was infectious and then they thought it was socioeconomic. They couldn't figure out what it was and it ended up being niacin deficiency. It was because we started eating a lot of corn. It's a long story behind that. But in any case, so, the US started fortifying foods in the 1940s. They started adding niacin, other B vitamins to flour. And so, that cured the pellagra epidemic in the US. Italy, they also cured the pellagra epidemic, but not by fortifying. They just made it so people started eating foods with B vitamins. He says that that is the reason that the US became obese and Italy didn't. It's because when we add these vitamins, it does a few things. It gives us the ability to turn the processed food into energy and fat. When they do studies on pigs on diets that might include processed feed, when they add the vitamins, the pigs get fat and it's linear. It's the more vitamins you add, the fatter they get. Basically, this idea that the added vitamins are making us fat, which is crazy.

Cynthia Thurlow: Sorry, no. So, synthetic vitamins, is he also accounting for what else is in the “chow” or the feed of these animals? I'm totally curious.

Melanie Avalon: Yeah, so that's the thing. There was rodent studies and pig studies. But if they were given feed that's processed without the vitamins, they would stay malnourished and actually die. And then once vitamins were added, they would live and also get fat. And the more vitamins you added, the fatter they got. If listeners are curious, whenever I'm prepping a book, I read the whole book. I take a lot of notes. If there are studies, I want to look at deeper, I look after having read the book. I haven't pulled up these individual studies. Just fact check them. But he says, with artificial sweeteners, this blew my mind, that they've done studies where basically, they'll have five drinks and they'll all be artificially sweetened. But then they'll have different levels of maltodextrin, which gives it the ability to add calories or not add calories. Basically, in this study, there were five drinks, they all tasted the exact same, but one had actually zero calories, one had 75 calories, one had 100 calories. It was different numbers of actual calories. 

When the participants would drink the drinks, if they drank the drink that matched the calories, the way it tasted, it tasted like a certain amount of calories based on sweetness. They drank the drink that had the same amount of calories as what it tasted like, their metabolic response rate when they would check it afterwards would burn that amount of calories. But if the drink had more calories in it than it tasted like or less calories in it than it tasted like, the body wouldn't burn it at all. It would just shut off the metabolism. He says, it's because the body gets really confused by all of these signals. When it gets confused, it interprets it as uncertainty and it has a loss aversion type mindset. So, it goes into fat storage mode, which blows my mind.

Cynthia Thurlow: Yeah, I'm sitting here, I'm just processing. One thing at this conference that I was at over the weekend, one of the doctors who's absolutely brilliant was saying that, “Medicine has lost its ability to be--" He was using the term of, “We've lost the ability to be humble. We've lost humility.” And so, I'm sitting here processing everything you're saying and I'm like, “Oh, I need to go read this.” Because I think it's so important to consider alternative perspectives. If you were to say to me, synthetic vitamins are driving all of these metabolic disorders or diseases that are contributing to it, I would never have made that connection. So, of course, now, I'm like, “Hmm, I need to go read about this.”

Melanie Avalon: I know. Or, the idea that you could have a drink-- You could add artificial sweeteners. Because what he talks about is, we have all these processed food products where they'll make it less calories. Not calorie free, but less calories by putting in some artificial sweeteners to lower the sugar load. He basically makes the case that, even though, it is less calories, all of the confusing signals, our body, basically, like I said, it enters a mode of uncertainty. So, it starts storing fat. It's crazy. He basically says that we need to eat whole foods where the nutrition matches what our brain is expecting.

Cynthia Thurlow: Interesting. Because I think it's so complicated, because our soil is so depleted. As an example, if we're saying, we're just going to eat arbitrarily organic fruits and vegetables as well, it's not going to have the same mineral content that it did for my grandparent’s generation. And so, I think it gets tough. I'm not suggesting we go and consume synthetic vitamins. But you just start to realize that a modern-day lifesaving, if you're eating pretty clean likely necessitates the utilization of additional supplementation, whether it's on our own or it's added to our foods. Preferably, on our own. So, we get to choose what goes in our bodies. But that opens up so much. You’re just really unpacking the processed food industry. On so many levels, we can take it from multiple different angles about how it's detrimental to our health and this is a new angle.

Melanie Avalon: Yeah. No, exactly. And that's actually a key question I want to ask him is, because he doesn't talk that much about supplementing in a vitamin form versus when it's in the actual food. He really just talks about it being in the food, because he says, “Basically, there's so much to when we're actually eating and then what is in the food and what our brain thinks is in the food.” He writes it like a page turner to-- He basically in the first chapter talks about the pellagra epidemic. At the end-- today, he compares Italy to the US and compares how it seems a very similar dietary approach from the outside. They still have McDonald's and they still eat a lot of high calorie food. But for some reason, we have an obesity epidemic. It's like a cliffhanger. He doesn't really address it to way later in the book. That was a long intro. Basically, I really recommend, at least that book and I need to go back and read The Dorito Effect and Steak, as well.

Cynthia Thurlow: No, that's really interesting. I feel I maybe during this three-hour drive to and from this rural part of my state I got through a book for a podcast guest I have on Thursday and I started reading another book by Jenna Kutcher, which is more of like a personal development book and I was like, “Gosh, I made such good use of that time.” I'm really proud of myself.

Melanie Avalon: Was it Morgan's book that you finished? 

Cynthia Thurlow: Yes. 

Melanie Avalon: I didn't know you're integrating her that soon. 

Cynthia Thurlow: Yeah. On Thursday. 

Melanie Avalon: It's so funny for listeners. Cynthia and I are so in sync. This week, I was literally listening to Morgan Levine’s True Age. Is that what it's called? And then I flipped over to check my text and it was sent Cynthia via being like, “Have you read this” and it was a screenshot of--? 

Cynthia Thurlow: Exactly. I was in the car. It depends. If it's a book, I think I may want to reference. I get the physical copy, a lot of other books I listen to and I enjoy that, too. But for me, I need that visual. I really need the visual.

Melanie Avalon: Yeah, same.

Cynthia Thurlow: Makes me weird. But-- 

Melanie Avalon: Oh, it's not weird. I'm the same way. 

Cynthia Thurlow: [laughs] We're very simpatico.

Melanie Avalon: Yes. Yes, yes. 

Hi, friends. I'm about to tell you how you can get 15% off of my favorite bone broth, which is an incredible way to open your eating window. And all of the bones in this broth, Beauty & the Broth are grass-fed with no antibiotics or hormones and are traceable. Also, if you're suffering from mold or any autoimmune disease, bone broth is a basis of a lot of those protocols. But you want to make sure, you are getting the best of the best. That's why I love Beauty & the Broth. Also, for all of you vegetarians and vegans, stay tuned, because there's something for you, too. I've been talking about the incredible health effects of bone broth for years. Bone broth is so nourishing for our body. It's rich in collagen, which can really support your gut health, your skin, curb cravings, boost your energy and your immunity. But there are a lot of brands out there, a lot of them have ingredients that I don't like and making it yourself can also be very time consuming. That's why I am thrilled about Beauty & the Broth. 

Beauty & the Broth was created by Melissa Boloña. She's an incredible actress and entrepreneur. I've had her on the Melanie Avalon Biohacking Podcast. So, I'll put a link to that in the show notes. But Melissa started Beauty & the Broth after she realized the profound effect that bone broth was having on her own health, specifically, gut issues and its ability to give her radiant skin perfect for the camera. She founded Beauty & the Broth, which hits everything I could want and bone broth. It uses 100% whole organic ingredients. Yes, it is certified USDA organic. It is one of the only few bone broth companies in the entire US that has a USDA certification for organic bone broth. It has no artificial flavors, no preservatives, no phthalates, no sugar, and something that I love, no salt. Friends, even other bone broths that I really love always have salt added. This doesn't. Her bone broths are made from grass-fed, ranch-raised beef and vegetarian-fed free range chicken bones from Certified Humane USDA Organic Farms. And they are all traceable. Meaning, you can find exactly where these bones came from. And all certified organic vegetables are used in the broth as well. There's no antibiotics, no hormones, only the good stuff. 

Here's the super cool thing about Beauty & the Broth. It can be a little bit of a hassle to transport bone broth. It's heavy, you have to keep it frozen. Guess what? Beauty & the Broth comes in shelf stable packets with no preservatives that you keep at room temperature and they are in concentrated form. That means that you add back water to reconstitute and you can make it any strength that you like. They're single servings, so you can take them with you on the go. And even on the plane, as yes, they are three ounces and they're delicious. Oh, my goodness, friends, they will just make you light up. They are honestly one of the most amazing things I've ever tasted. And for all of you vegans and vegetarians, Beauty & the Broth has a brand new vegan broth concentrate. It is USDA organic and is a slow-simmered broth, which is reduced into a thick gelatinous gel. You mix it with hot water and turn it into a delicious sipping broth. It features organic mushrooms, and chickpeas, ginger, seaweed, and pea protein. It is so delicious. So, definitely check that out.

If you've been looking to finally jump on the bone broth train, do it now and do it with Beauty & the Broth. And Melissa has an amazing offer just for our listeners. You can go to thebeautyandthebroth.com or melanieavalon.com/broth and use the coupon code, MELANIEAVALON to get 15% off. That's thebeautyandthebroth.com with the coupon code, MELANIEAVALON for 15% off. All of the listeners who have tried it ever since I aired my episode with Melissa have talked about how much they love it. It is so delicious. You guys will definitely love it. So, definitely check that out. And by the way, bone broth does break your fast. This is something that you want to have in your eating window. In fact, it's an amazing way to open your eating window, because when you're in that fasted state, when you take bone broth as the first thing, all of those rich nutrients and collagen go straight to your gut, help heal your gut, help with leaky gut, help digestive issues. And again, you can go to thebeautyandthebroth.com and use a coupon code, MELANIEAVALON for 15% off. And I'll put all this information in the show notes. All right, now, back to the show. 

Melanie Avalon: Shall we answer some listener questions about fasting, the other side of food? 

Cynthia Thurlow: Yes. 

Melanie Avalon: All right. So, to start things off, we have a question from Violet and the subject is: “IF timeline.” And Violet says, “Hello, this is my 109th day of fasting. I was wondering if you can give me a rough timeline on when I might see more fat loss. I've definitely decreased in clothing size. I'm not as hungry, but since I've been at this a while, I was wondering when more fat loss can be expected. What is the average for an IF-er to see bigger results? Six months, a year? I know everyone is different, but I'd love to have something to look forward to and keep up my momentum. Thank you so much for your books and inspiration.”

Cynthia Thurlow: This is a great question, Violet. I always come at this as a clinician. So, I don't know your age or life stage. I'm not sure, if you're you no younger like in your 20s and 30s pr if you're a perimenopausal, menopausal. That will definitely impact that loss for a number of different factors. I think it's important even if we're fasting that we consider the quality of the food that we're eating. And by that, I mean, are we eating an anti-inflammatory diet, are we eating a less processed? I remember I said less that doesn't mean no processed food. I'm saying less processed food. What is your stress management like and that doesn't mean five minutes of meditation? Are you exercising? Because one of the most important things, I think when women are talking to me about fat loss, I think about strength training, I think about high intensity interval training, and I think about just being physically active during the day. 

It was interesting at this conference I was at. One individual indicated, “If you exercise hard for an hour and then you spend the rest of the day sitting on your butt, you've just undone all the good of that exercise.” I think it's important to track your movement and you don't have to be vigilant about it. I know how much I walk every day, just during my day, or with my dogs, or cumulatively with exercise. I think that's important. Strength training, high intensity interval training really being active during the day, not being a couch potato, nutrition and then where you are age wise, but I also think about sleep. And my standard foundational approach to women with fat loss, and weight loss, and things like that is, if your sleep isn't high quality, high-quality sleep means you wake up rested, you really don't need an alarm clock, but you can easily get up and get out of bed. If you're not getting high-quality sleep, you're losing out on opportunities to support your body, not just hormonally, with leptin, ghrelin, these appetite regulatory hormones, blood sugar, insulin, but it also impacts your food choices that you're making. 

I really take a foundational approach and those are the things that I would look at first. I would say most women-- intermittent fasting for a lot of people, it's not instantaneous gratification. I think it's more unusual that people get an instantaneous gratification. And so, I think it is all about staying with the mindset of, “This is a journey, not a race.” Unfortunately, the processed food industry, the weight loss industry, which is a trillion dollar a year industry has convinced us that weight loss should be effortless, fat loss should be effortless. You take a potion, a pill, or powder, and it happens effortlessly. I'm here to tell you as a clinician that is not sustainable. What I generally recommend is giving yourself a solid three to six months, celebrate the non-scale victories, your clothes feel looser, make sure you take measurements. I think that's very helpful. I'm not suggesting you get on the scale every day. But measure your waist, measure your hips. If you have another problem area that bothers you, then you can appropriately track it objectively. But I think that that's probably where I would start from. And in terms of really giving yourself grace, because I think we as women, we're so hard on ourselves. I have been that person and I speak with love when I say this that really giving your body time, because we get healthy to lose weight or lose fat.

It's not supposed to be instant gratification. In fact, that's a rare occurrence. I see more often than not with women, especially if you're still your peak fertile years or you're still getting a cycle every month. Your body is conditioned for reproduction even if you're choosing not to have a baby. When a woman is in perimenopause and menopause, your hormones start recalibrating themselves and it gets a little more challenging to lose fat. It does not mean it's impossible, but you have to be more diligent. So, those are the things I would definitely consider, Violet, and I'm sure Melanie, you have some insightful recommendations or suggestions as well.

Melanie Avalon: First, quick question. What was the theme of the conference that you spoke at?

Cynthia Thurlow: It was called “Momentum in the Mountains.”

Melanie Avalon: Was it just all different health topics or--? And what did you speak on?

Cynthia Thurlow: Well, they asked me-- This is usually what happens. I was the only female that spoke and so, they wanted to have a female slanted. This is like the story of my life. They wanted me to have a female slanted conversation. And so, I talked about perimenopause and menopause, and then I slid into metabolic health, which is always my natural progression. But I was able to really dig in deep and a lot of women came up to me and said, “Gosh, I wish I had known that information 20 years ago.” So, that's what I spoke about. But I had a cardiovascular surgeon, who spoke before me, who was talking about metabolic health from his perspective. He wrote a book called Stay off My Operating Table and he means it. [laughs] And then I had a doctor after me, who was talking about childhood obesity. And then Vinnie Tortorich, who's absolutely hilarious. For any listeners that don't follow him, he has a podcast called Fitness Confidential. He's one of my favorite people. He's just a no muss, no fuss kind of guy, was talking a lot about what goes on in the food system. And so, it was nice variations on themes throughout the discussion. But yeah, it was great. It was a lot of fun.

Melanie Avalon: Very cool. Yes. So, for Violet’s question, [chuckles] I always feel I'm not the best person to have data on this since I don't actively work with people who are trying IF all the time. I really just have my experience and then I have the vague sort of people writing in or people in the audience saying like, “I started intermittent fasting and I’m finally losing weight.” But for my experience, because it's been so long ago that I first did it. I was thinking about this. Looking back, I don't remember quantifying the speed of the weight loss when I started fasting. But I remember there was a huge feeling of a paradigm shift in my body, which was that prior to IF, I always felt with dieting that I was actively trying to lose weight and looking at the pounds and felt like, “I would lose and gain” and it just always felt like a challenge and a struggle. And with fasting, something clicked and then I finally felt, “This is very not scientific.” I'm talking about my feelings. But I finally felt during the day when I was fasting that I was literally burning fat which I was. And so, basically, it felt I went from a trajectory of yo-yoing or struggling to “oh, okay, every single day I am burning fat.” It felt I was making slow and steady for progress movement. 

And on top of that, so, I know she's asking like what is normal and she's looking forward to keeping up her momentum. In general, there's a lot of magic and Cynthia touched on this, like, the importance of what you're eating and everything, but there is definitely a lot of magic in the foods that you are eating. I think a lot of people will be on a standard American diet, not fasting. Eating all throughout the day, and they can start fasting, and maintain that standard American diet, and lose weight, which is great. But on top of that, if you are also looking at the food choices, there's just a lot of magic that can happen there. I feel like a broken record, because I say this all the time. But on the macro side of things, so, for some people, doing low carb is really, really magical, so that might expedite the weight loss. If you are existing in that low carb world, not necessarily embracing the idea that low carb, for example, has to be super, super high fat. Because you could be doing low carb, high fat and there might be a lot of potential to lose more weight, if you titrate down the fat a little bit while still staying moderate to high protein, of course. 

And then on the flipside, some people do really well, actually, with a higher carb, low fat approach. And that can be something that can really catalyze weight loss. I think really it's all about finding what works for you, but there's definitely magic that can happen if you tinker the food choices on top of just the fasting. Of course, I love everything that Cynthia said about lifestyle choices and sleep and all of that and that's huge. But yeah, I feel it's very individual, which always feels like a cop out answer. But people's bodies are different and they respond differently to change. So, I don't know that you have to even focus on what's normal or average and rather just focus on what is or is not working for you personally. So, you don't have to compare yourself to other people.

Cynthia Thurlow: No, and I think that's important, especially we, as women do a really not so stellar job of we're chronically comparing ourselves to others. Even when I'm teaching IF:45, which is my signature program for fasting for women, the one thing I always tell them is put your blinders on and focus on you. Because we tend to-- we see that there's someone else in the group or someone else, we know that effortlessly loses weight or maybe that's our perception. And yet, we don't know what's going on underneath the hood, if you will. And so, I always say that people come to intermittent fasting, because they want to lose fat or they want to lose weight, and then they end up staying for all the other benefits. And giving it time and I think I've shared, if not on IF Podcast, certainly, on my own that when I started fasting, I didn't lose weight right away. And obviously, I was in my 40s when I started doing it, it took longer. 

But for me, the single most important thing I did that allowed me to lose that last bit of perimenopausal weight was an elimination diet. Getting dairy out of my diet was abso-- Even though, I eat dairy so sporadically was a game changer for me. And so, I always say to people, “Sometimes the foods you love may not love you back.” So, really getting diligent about-- Maybe you do a whole 30 for a month, maybe just see how your body responds to reducing inflammation in the body. I would get creative and be open-minded to trying different things to see what will be most effective and efficacious.

Melanie Avalon: Perfect. I love that. That reminds to me because I was looking at her last sentence, “Thank you so much for your books and inspiration.” Cynthia, we forgot again. Do you want to talk about the giveaway?

Cynthia Thurlow: Yes. So, I have not been good about mentioning this in our episodes, but we are ready to draw a winner. And the winner, all you have to do is purchase my book, Intermittent Fasting Transformation and submit a review. So, if you bought it on Amazon, submit the review, screenshot it, send it to us at questions@ifpodcast.com and we will submit your review and your book purchase. And if you bought the book when it first came out, you can still do that. Just screenshot it and send it to us. But we're super anxious to send some really great goodies that some very generous companies shared with me during the book launch and I really would love to be able to provide an opportunity for some of the IF Podcast listeners to get some fun things. But we will poll one person. Let me just be make sure that's very clear. So, just send that to questions@ifpodcast.com.

Melanie Avalon: Yes. And so, to recap, everybody, I think can benefit from Cynthia's book. It is so amazing and it's such a valuable resource. So, all of the stuff that we talk about on here with fasting and hormones in women's specifically, and protein intake, and how to do this, and sleep and lifestyle, it's all in there. It can definitely benefit listeners from getting her books. If you already have it, definitely, super easy. Just go write a review on wherever you bought it and send us that screenshot. If you haven't bought it, now it’s a great time to get it and write that review. Yeah, so, we'll pick a winner and send out lots of goodies. 

Friends, I'm about to tell you how you can get 50% off a product that has truly changed my life. Do you experience stress, or anxiety, or chronic pain? Do you have trouble sleeping at least once a week? If you do, trust me, you are not alone. I personally have explored so many avenues for how to have a healthy relationship with stress and finding the world of CBD oil has been absolutely incredible for that. After doing more and more research, I realized just how incredible the health benefits of CBD are. CBD regulates your cannabinoid system kind of like an adaptogen making you feel better naturally. It's not addictive, it's not a crutch, basically, it's just helping your body function better when it comes to stress, anxiety, pain, and sleeplessness. I take it daily for my mood and the effects are profound. In fact, I even got robbed last year and I went from crying with stress and anxiety to taking some Feals and laughing. I said to my mom, "Mom, see how effective this is?" Due to all of its health benefits, we knew we wanted to partner with a CBD company for the podcast. But I have very stringent criteria. You guys know this. So many brands approached us and I kept just saying, “No,” because nothing fit all of my criteria. I wanted CBD oil that was full spectrum, tested for purity, organic, made with MCT oil as the carrier, and that I actually experienced benefits from. That's a pretty tall order to fill. We said no to a lot of brands, and then Feals came along, and it was meant to be. I personally tried it out and started seeing massive effects on my sleep and stress. Feals is so easy to take. You can just put a few drops under your tongue and you'll feel the difference within minutes. I truly do feel it within minutes.

Of course, it is important to remember that CBD works differently for everybody based on your own unique cannabinoid system, so you might need to work to find your perfect dose. Experiment over the course of a week or so, and you may find that you need more or less depending on the effects that you're looking for. I'm also super grateful because they have an incredible offer for our audience. You can start feeling better with Feals. Become a member today by going to feals.com/ifpodcast and you'll get 50% off your first order with free shipping. That's F-E-A-L-S dotcom slash IFPODCAST to become a member and get 50% automatically taken off your first order with free shipping. feals.com/ifpodcast. 

When you get that offer, you'll be joining the Feals community and you'll get Feals delivered directly to your doorstep every month. You'll save money on every order and of course, you can pause or cancel anytime. So, definitely try it out for the first month with our code for 50% off and see how it works for you. We'll put all of this information in the show notes. All right, now, back to the show.

Cynthia Thurlow: Do you want to jump into our next question? 

Melanie Avalon: Sure. 

Cynthia Thurlow: This is from Liv. And so, the subject is: “a one-to-two-hour window, constipation, when everything balances out.” “Hi, I adore your podcasts and love to skip around depending on the day and what I need regarding tips, IF education and motivation. I'm a 30-year-old female and I have been athletic and health food based my entire life. Growing up on a fruit orchard with health-conscious parents was very helpful in my building blocks were plant-based and Whole Foods eating. I worked in a Whole Foods store through high school and college, and I've always been drawn to naturopathic and holistic medicine. That said, I avoid junk, processed foods, and excess of dairy or meat. However, like most people, I keep a balance and do eat desserts every now and then. I drink wine regularly. I used to kill myself at the gym to knock out my stubborn 10 pounds of extra fat. That seems to be so cozy around my midsection and hips. I could run five to seven miles a day and nothing was as successful for me as intermittent fasting. I've been on and off this way of life for five years and never stuck to it for maintenance as I should have. I am now back on, I'm assuming two weeks eating with in a one-to-two-hour window and feeling amazing. 

Weight is falling off again and I'm sticking to my tennis game and more leisurely physical fitness. Huge plus in this heat in Ohio. My question is, one, I have not heard discussed too much on your podcast or maybe I'm missing the episode. Pooping.” You know, as a nurse I love these questions. “Yes, can we all admit, we poop and discuss IF and pooping?” Absolutely. “I am someone, who likes to poop every day and when I don't, I get irritable. Does my window reflect too small of an eating window to produce a daily bowel movement? Is constipation a temporary thing? As women, I feel we are more subjected to this physiologically. How long does it take to regulate? Can you please describe your experiences and/or share your research on this topic? I think ketosis and fasting can really change things for people here and I feel it is valuable to discuss in order for me to feel a little more normal. Also, I've read that most people are carrying around a minimum of 10 pounds of bile. Yay, yuck. I have to guess that if IF helps this, because sometimes, and sorry, this is nasty. Sometimes, what comes out in these first few weeks back to fasting feels that type of stored sludge for lack of a better term backing me up. No shame in the pooping game. Love you both, Liv.” That warms my nurse practitioner heart. I love to talk about poop.

Melanie Avalon: Oh, that I'm so excited. Then we both do. So, this is great. And actually, it's funny, because she said that she hadn't heard it discussed on the podcast before. We've had a lot of episodes on it. Just maybe not recently. And so, this is a little resource for listeners. If you go to our website, ifpodcast.com, there is a search bar there. Because we have transcripts on every single episode, if you search for keywords, it will find the episodes. So, you could search for poop, but more likely, if you search for constipation that'll probably bring up a ton of episodes. But it's nice to revisit it now and it's nice to visit it with Cynthia. [chuckles] I get excited because there're so many topics we've talked about so much on the show, but I get to discuss it all anew, because I haven't heard your perspective specifically. So, it's very exciting for me. Yes, but so my thoughts on all of this, whoo, I have a lot. 

First of all, so, I do struggle with, I know, this is a way that Cynthia and I are different. I do struggle with constipation. And Liv, when you say that you're irritable if you don't have a daily bowel movement, irritable is an understatement for me. I have to keep things moving and I really have to stay regular. And I've found the system that works for me to do that and I stick to it. But I've learned a lot over the years. And interestingly, I've first started struggling with this issue. It's hard to know, because a lot was going down. I had a living situation from 2012 to 2014, where I was in an apartment that had black mold and there was carbon monoxide leaking every night and that's when I first got hypothyroidism. And so, it's hard to know what was what. At that time, that's the first time I took the antibiotic. Some people might be familiar with for SIBO called rifaximin. That's when I started having issues with regularity and digestive issues was after taking that antibiotic. I don't want to scare people away from it because for some people it's a game changer for SIBO, which is small intestinal bacterial overgrowth. But for me, it had some negative side effects. 

To go through some of your questions, she's asking, if, because she's eating less in a shorter window, is that affecting the bowel movements or not? It's really interesting, because and I know that Liv is in the plant-based sphere. If you look at what people are saying and in general, people will say, “Add lots of fiber, add lots of bulk to encourage bowel movements.” And for some people, that really works. For others, it doesn't. For others, it causes the exact opposite problem, it causes bloating, and things just get backed up. If things aren't moving and then you're just adding more fiber to the fuel, then it just gets worse and worse. And especially, people with digestive issues who are creating methane, if you have methane-producing bacteria, they eat the food and they produce methane. And methane actually works as a neurotransmitter in the GI tract that stops motility. So, it becomes a vicious cycle where you might be adding more fiber to try to move things along and it's just making things back up even more. That's I know what I experienced for a while. 

I went through a period where I was like, “I'm going to find the right fiber that will keep things moving that just made everything really worse.” What ended up working for me was a low FODMAP diet. That works really, really well for me. But that said or and [chuckles] it's interesting, because so, people in the carnivore sphere and the low-carb sphere, but really the carnivore sphere, they'll go on a zero-fiber diet. A lot of them will say that they have the perfect bowel movements. Before that, they were constipated and then once they caught up with the fiber, everything was great. And they often reference, they'll say-- Studies will show that people on a no fiber diet that it resolves constipation. Everybody quotes the study. There's only been one study, but it's a pretty telling study, but it's very small. It was only in a few people, but they basically found that-- I think all people had existing GI issues and they went on a zero-fiber diet and in every single person, it resolved their constipation which is really interesting. I just wish there are more studies looking at this. But back to the question, I feel I'm circling all-around of, is more food required for bowel movements? Based on everything that I just said is very individual, I think. Some people do not require that bulk and they will have just dandy bowel movements. Some people do benefit from having a certain amount of bulk or a certain amount of fiber and things like that. We have heard from a lot of listeners that they start fasting and they struggle with constipation. It may or may not be temporary. So, it may resolve, it may not. If it's not resolving, there are a lot of things that you can try. 

What really, really works for me is magnesium. It is my favorite thing. I'm super excited because I did recently launch my magnesium supplement. So, that's Magnesium 8 by AvalonX. You can get it at avalonx.us and the coupon code, MELANIEAVALON will get you 10% off. I think getting your magnesium levels, because most people are likely deficient that's for a lot of reasons. We talked about this-- We did a whole episode on this. You can check out Episode 276, if you'd like to learn more about magnesium deficiency. But I think getting your magnesium levels up in general can be good for motility. Specifically, high dose magnesium to keep things moving. So, I take my AvalonX Magnesium 8 and then I also use Natural Calm, which is a magnesium drink form. I use that every night and that really, really helps for me to keep things moving. Some people will use high dose vitamin C that will work as well or may work as well. I'm all over the place with this. But I did recently listen to a fascinating episode all on the gut and the connection between the nervous system and motility in the gut. It's actually Peter Attia’s-- At the time of this, his most recent episode and it's with a GI doc.

Cynthia Thurlow: I'm halfway through it. I'm like, “Dang, it's a two-hour episode. It is excellent.” But it's almost harkening me back to my days at Hopkins, when we would get lectures from med school faculty. It is very detailed. It nerds me out and I love it and Melanie loves it. It's very detailed. If you're part of Peter Attia’s membership, which Melanie are both part of you get all the behind the scenes, little nuances, but that's an excellent podcast. I'm going to come at this as a clinician. When I think about poop, obviously, nurses and nurse practitioners, we talk a lot about poop. It's completely our zone of genius, because doctors generally don't like to talk about it. I think about a lot of things. Could it be that you are not eating a large enough bolus of food that is telling your GI tract, there's actually a mechanism in the gut that signals the innervation in the small and large intestine and move things forward as you eat? I think a great deal about something as simple as what's your hydration status like, are you moving every day? Exercise will actually help with peristalsis. I also think a great deal about the parasympathetic nervous system. So, we have the autonomic nervous system and this is a branch. 

Sympathetic nervous system is when you're being chased by a rabid animal and parasympathetic is rest and repose. We actually have to be in the parasympathetic to poop. I cannot tell you how many patients and women I've spoken to over the years, who think if they're super stressed, they can force themselves to poop in five minutes. That's not how it works. When you've got a two-year-old banging on the door in the bathroom and you have five minutes to go out the door, that is not the time. You actually have to set aside this time to go. I've had lots of women, who've had success with a Squatty Potty. They just need to reposition things. 

Melanie Avalon: Squatty Potty is the best.

Cynthia Thurlow: Yeah, Squatty Potty, I would say bitter foods, arugula, bitter greens, things that will help with viscous bile. Anyone’s thinking or talking about constipation, already thinking about viscous. The bile in the gallbladder is viscous and thick and in there it's having a hard time emulsifying and breaking down fat. The bitter foods, things that will be helpful for bile are artichokes, shaved beets, carrots, all very supportive and nurturing. One of the tricks that I learned how to use, like, when people are having pretty benign constipation, one tablespoon of fresh ground flaxseeds combined with one tablespoon of fresh ground chia seeds. And that together is magic. You can throw it in a smoothie, you can throw it on top of a salad, very, very effective. And then I always say, you can also use things like aloe vera juice. Even a quarter cup, it doesn't taste great. But if it's a frustration and definitely sounds like this young woman. Liv definitely gets frustrated when she's not able to go and I completely understand that. 

Other things that I think about are, you mentioned, a lot of people will recommend fiber. I think this is highly person dependent. I can tell you that three years ago, when I spent 13 days in the hospital and was in gigantic GI distress mode, I didn't have a solid stool for a year. And you believe fiber made my body very inflamed and very miserable. I went back to eating just meat for nine months and that helped me get over that. So, that's very dependent on the individual. With that being said, there is value in consuming, maybe you haven't-- Have an apple every day. You will be getting in some fiber or maybe you're having salads. That's one thing I generally recommend is make sure you're getting some uncooked vegetables and fruits into your diet, because that may be beneficial, but again, highly dependent on who you are. I also think about prebiotic rich foods. It's interesting. I just interviewed Vincent Pedre on my podcast and we were talking about the research around prebiotic rich foods, even fermented vegetables like a tablespoon of fermented cabbage, or okra, or whatever fermented vegetable you like can be very beneficial to nourish the right bacteria in the gut microbiome. So, that's where I come from. But a lot of its--

There is a great deal to it that's psychological. I would experiment, as Melanie said, there are supplements that can be helpful. I think about Triphala, that is an ayurvedic option that can be very beneficial. Magnesium and Melanie's magnesium is a nice choice. There's a product by Designs for Health called TriMag, I try every supplement out that I recommend to clients and patients. That destroyed me. Because I have a very vibrant digestive system, I go effortlessly and easily. I only share as to give you context and I actually gave it to my mother who struggles with constipation and she loves it. It's just a powder that she takes before bedtime. But there are lots of options and I do like magnesium. Vitamin C can be tricky. I say this from personal experience, because I sometimes will add vitamin C to my liquids if I'm under a lot of stress. There's a very fine line with vitamin C. You'll know if you've had too much, because you will get loose stools. But it's not always predictable. So, I would be careful with vitamin C, although it can be very, very helpful. But hopefully, those are the things that will be helpful for you. 

I would say and I think listeners know this about me. I don't like women to have a one-to-two-hour feeding window. I do think you genuinely need a wider feeding window. And ironically, maybe, Melania. and I can talk about this on the next episode. But I was watching some research that Ben Bikman was providing on his brilliant IG account. He was talking about the role of mTOR signaling and how if women are doing too much fasting. That was the context of what he was talking about that that can impact fertility in nonbeneficial ways. And obviously, I don't want to get off on a tangent, but I just wanted to interject. I like women to eat within a larger feeding window. I know, Melanie eats a large bolus of food over several hours and I just think it's very hard for women to get in enough protein in a very, very short window, unless you're a unicorn. And there may be a few unicorn listeners. But from my perspective, I'm always very protective of the protein piece. But constipation, I totally get it. It can be very, very frustrating. I do find that for most women that struggle with this, it can be not just a physiologic component, it can also be an emotional component really getting into that parasympathetic, really setting aside time in the morning, or the evening, or whenever your body likes to have a bowel movement. Just setting that time aside, so that you can actually have that and then integrating nutritional options and supplements that can help support your body.

Melanie Avalon: I'm so glad you said all that made me think of-- I took some notes because that made me think of quite a few different things. First of all, on the magnesium piece, I forgot one of the ones that really helps me. And I actually want to develop my own version of this as a standalone separate magnesium in the future. But I think it's called Mag-07 and it's just magnesium oxide and that is a very poorly absorbed form of magnesium.

Cynthia Thurlow: 11% is what you absorb. 

Melanie Avalon: It has a very osmotic effect in the intestines and that works really well for me. And so, I plan to make my own version, especially, because I don't like some of the fillers in it. But yes, so that version specifically, I've played around with it. I don't know how you say it, the Triphala. I know a lot of people, it's game changes for them. It didn't really work for me. The herb that did work and I know this is a little bit controversial, because it is a stimulant herb. It potentially has the possibility of reliancy on it, but cascara can work for a lot of people, especially, if you're in a rut.

Cynthia Thurlow: I also think about Smooth Move tea.

Melanie Avalon: Oh, yeah, I'm having flashbacks to my really constipated days. [laughs] 

Cynthia Thurlow: My kids would kill me, if I told share this with listeners, but it's okay. We're all women and people, who are supportive, right? I think about how I had a kiddo, who really struggled with constipation. And so, we had this whole formula of what we would use. Every once awhile, he needs Smooth Move tea, which I recommend you brew half of what is in there and save the other half for another time. But that can be very effective. Senna, but those are things you don't want to be taking regularly because it can make your bowel lazy.

Melanie Avalon: Yes. And there's definitely a difference, at least in my personal experience. The urgency related to the osmotic effect of magnesium or potentially vitamin C, for example, it can have an urgency feeling loose stools like Cynthia was saying. But then the stimulant version, so like senna, the Smooth Move tea, cascara, that can be more, at least for me of like a crampy, really unpleasant urgency that, it's urgency to the next level urgency.

Cynthia Thurlow: It's a signal that you got to go.

Melanie Avalon: Yes. Because it's basically, the osmotic version is working, because it's pulling in all of this water. It's signaling to the intestine with that bulk to push things forward. But with the stimulant versions they are actually-- I don't know the details of it, but it's actually communicating with the intestines to move.

Cynthia Thurlow: It's like a whip.

Melanie Avalon: Yes. Yeah, that's a good example. [laughs] Then I'm glad you mentioned the bile again, because I wanted to answer. She was saying 10 pounds of bile. I think she's confusing bile with fecal matter, because I just googled it and according to a 2010 study on the gallbladder, the liver produces about 27 to 34 fluid ounces of bile every day.

Cynthia Thurlow: Mm-hmm. It's small amount. I mean the gallbladder is small.

Melanie Avalon: It's not 10 pounds of bile. And then even on top of that, I have wondered about that and I think it varies drastically between individuals for two main factors. One, the actual amount of bulk in your stool based on what you're eating and your gut bacteria. And then number two, the transit time. Some people have faster transit time, some people have slower. There's a lot of permutations of different factors that could affect how much stool you actually have in you. Question for you, Cynthia. I know I've asked you this before. When you did the nine months of the meat only, did you have regular bowel movements on that? 

Cynthia Thurlow: Yeah, but it was-- Sorry, TMI, it was still literally just liquid all the time. And no one was worried about it, I just kept saying, “When am I going to have a formed stool?” There's something called Bristol's Stool chart and this is something we can include in the show notes. That's a good way to describe your poop. You can see visually, people that are absorbing too much water versus not enough. If you're absorbing too much water that's diarrhea. If you're absorbing not enough, you'll have pebbles and it can be hard. You can develop hemorrhoids internally or externally. And then there's the perfect poop, which is number four. And so, it gives people an idea of what's your normal and then you can actually have a communication with your healthcare professional, if you ever need to. 

The other thing that I was thinking about is, just this whole mindset and methodology about being comfortable talking about things that are very normal. But yet, as a society, we get uncomfortable talking about bodily functions. And so, I'm glad that we're having this discussion, so that more women-- Wherever our listeners are, I think we're predominantly women. I know we have many male listeners as well. I think that whomever is listening that they understand, you're more than welcome to ask these kinds of questions because it's so common. I mean, everyone poops. In fact, I used to have a book for my boys that was like, Everyone Poops and it was all these different types of animals and how different their poop was. Of course, as a healthcare provider that was the greatest book ever. I think I got it at the San Diego Zoo. But the point of why I'm sharing this is to encourage people, don't feel uncomfortable sharing this kind of information. There's probably 20 other people listening who had the same question.

Melanie Avalon: I've actually been thinking about that a lot recently not with the poop subject, but I released my episode week before last with Dr. Laurie Mintz who wrote Becoming Cliterate, which is about orgasm equality. 

Cynthia Thurlow: I need to listen to that. 

Melanie Avalon: Oh, it's so good. And her work is so good. But it's made me realize how far I've come with all of that, because speaking to what you were talking about how we have these certain topics that are off limits to talk about, so sexual health and sexual awareness and all of that was something I did not talk about. If I heard a podcast or talking about it, I was like, “Oh, how scandalous?” I released that episode now and didn't even think twice about it. But what's funny is I've been getting so much feedback from listeners thanking me for talking about something that people are uncomfortable talking about. And every time I get that, well, it's helpful, because it makes me feel better about talking about these types of things, but also, it reminds me just how much subjects are taboo.

Cynthia Thurlow: Well, even talking about aging, Melanie, I was talking about this in the context of my lecture and I was saying how embarrassed I was when I hit the wall of perimenopause and did then do a TEDx about it and then to be talking about it all the time. I've come to realize, even as a healthcare professional, my faculty members arguably went to one of the best medical institutions in the country. And no one talked to us about this time. It's like, women go off to pasture. And so, those topics that were uncomfortable to talk about, we need to be talking about. Whether it's talking about our sexual health, or talking about aging, or pooping, we need to have opportunities to explore these topics and do it, so there's less stigmatization. I think maybe my children's generation might grow up differently than certainly my generation did. 

But even now, I still feel what I hear for most women and obviously at middle age a lot of women just don't want to have sex. And so, that's the new thing that people bring up in conversation and then it runs like, “Yeah, we don't want to talk about that. [laughs] We don't want to talk about that.” That's a whole separate-- You should be having that conversation with your best girlfriend, not amongst mix company. My hope and certainly our hope and our intent is that we can have these conversations, so that people have a safe place to be able to get input and feedback on.

Melanie Avalon: I haven't aired it yet. Did you connect with Dr. Sherry Ross?

Cynthia Thurlow: I did but I think she's going to end up being like a 2023 guest because she can only record on Fridays or after 5 o'clock and 9. I was like, “That doesn't work for my schedule.” [laughs] But I will. We're connected with her, but thank you for that.

Melanie Avalon: She wrote a book called She-ology. She's a celebrity gynecologist. I'll be airing that in the next few months. But one of the biggest epiphanies I had even with that was growing up in the south, girls, we didn't go to gynecologist. And I think it was because they thought by going to a gynecologist who would encourage having sex. And just stepping back, I'm like, “This is such a problem.” There's a lot happening with the vagina that has nothing to do with sex that needs to be looked at by a healthcare practitioner.

Cynthia Thurlow: Yeah, and that's on every level. That's one thing that my conversations with women and so, I have a program called Holistic Blueprint, where we do the DUTCH, and we do the GI map, and we do a lot of testing, we have a lot of conversations. And when women are speaking with me privately, that's when they'll start the conversations. And so, a very common conversation for women to be having is the changes that occur in middle age within the vagina and the vulva or vagina/vulva. And some of them are so stigmatized like, “Oh, I'm not supposed to talk about this.” I'm like, “Well, what's the other option? Suffer in silence? We don't want that either.” So, I'm excited to hear your conversation with her.

Melanie Avalon: Exactly. Awesome. We're on the same page as per usual. So, basically, listeners, the take away is, ask us all the questions.

Cynthia Thurlow: Please do. Poop is a subject. I could talk about till the cows come home. And this is one of the few things where Melanie and I are very divergent on. It's easy for me, not as easy for Melanie. But it also gives us different perspectives. It really makes me reflect on how common women believe or just people in general, like, my patients. All my patients used to think it was normal that they would poop twice a week. I'm like, “Listen, that is not normal. [laughs] It's not good.” Making sure that if it's a chronic issue or if it's something that's new and concerning, make sure you see your healthcare professional. That is one thing I just want to dovetail in there and say, “If it's new, and it's persistent, and you're having other changes, make sure you have a conversation with your healthcare professional.” But definitely these nutritional changes and stress management supplements that might be an easy fix. But if those things aren't working, you're still having symptoms, you definitely want to follow up with your local healthcare professional.

Melanie Avalon: And actually, just one last point to that point. I totally forgot the thing that really switched the lever on, because I was in a period where I was trying everything. I was having so many flashbacks during this conversation, because it was all during a time where I was just trying all the things and nothing was working. It wasn't until I saw a practitioner and got put on thyroid medication for my hypothyroidism that that really was a game changer in the motility department. So, yes, yes, yes. 

Well, this has been absolutely wonderful. So, a few things for listeners before we go. If you would like to submit your own questions for this show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. The show notes will be at ifpodcast.com/episode278. They'll have a full transcript and links to everything that we talked about. Definitely check that out. Reminder to enter the giveaway to win all of the amazing goodies from Cynthia. Again, for that, if you already bought a copy of her book or if you do buy a copy of her book now, either way, just leave a review on whatever platform you bought the book from. Send a screenshot of your review to questions@ifpodcast.com and we will enter you into the drawing. And yes, you can follow us on Instagram. We are @ifpodcast. I am @melanieavalon. Cynthia is @cynthia_thurlow_. I think that is all the things. So, anything from you, Cynthia, before we go?

Cynthia Thurlow: No, keep the great questions coming. I think we've been very humbly and beautifully overwhelmed with the outpouring of support and we look forward to diving into questions next week.

Melanie Avalon: Likewise, and happy early birthday, again.

Cynthia Thurlow: Thank you.

Melanie Avalon: I will talk to you next week. 

Cynthia Thurlow: Sounds good. 

Melanie Avalon: Bye. 

Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs and original theme composed by Leland Cox and recomposed by Steve Saunders. See you next week.

[Transcript provided by SpeechDocs Podcast Transcription] 

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Jul 10

Episode 273: Uric Acid And Fat Gain, Fruit & Fiber, Vitamin C, Oxidative Stress, Low Fructose Diets, Metabolic Flexibility, And More!

Intermittent Fasting

Welcome to Episode 273 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Cynthia Thurlow, author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.

Today's episode of The Intermittent Fasting Podcast is brought to you by:

 JOOVV: Like intermittent fasting, red light therapy can benefit the body on so many levels! It literally works on the mitochondrial level to help your cells generate more energy! Red light can help you burn fat (including targeted fat burning and stubborn fat!), contour your body, reduce fine lines and wrinkles, produce collagen for epic skin, support muscle recovery, reduce joint pain and inflammation, combat fatigue, help you sleep better, improve mood, and so much more!! These devices are literally LIFE CHANGING!! For A Limited Time Go To Joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

BUTCHERBOX: Grass-Fed Beef, Organic Chicken, Heritage Pork, Wild-Caught Seafood: Nutrient-Rich, Raised Sustainably The Way Nature Intended, And Shipped Straight To Your Door! For A Limited Time Go To Butcherbox.com/ifpodcast And Get Free BACON For LIFE And $10 Off Your First Order!!

AVALONX SERRAPEPTASE: A proteolytic enzyme which may help clear sinuses and brain fog, reduce allergies, support a healthy inflammatory state, enhance wound healing, break down fatty deposits and amyloid plaque, supercharge your fast, and more! Avalonx supplements are free of toxic fillers, common allergens, heavy metals,  mold, and triple tested for purity and potency. Get on the email list to stay up to date with all the special offers and news about Melanie's new supplements at Avalonx.Us/emaillist, and use the code melanieavalon for 10% on any order at Avalonx.Us and MDlogichealth.com!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get Free BACON For LIFE And $10 Off Your First Order!!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At melanieavalon.com/beautycounter or beautycounter.com/cynthiathurlow And Use The Code CLEANFORALL20 For 20% Off PLUS Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: Melanieavalon.Com/Beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

The Melanie Avalon Biohacking Podcast Episode #146 - Dr. Rick Johnson

Ep. 205 – Fructose – The Driver Behind Metabolic Disease with Dr. Rick Johnson

rick's Beginning

the surprising truth about hummingbirds

blood glucose metabolism in hummingbirds

fending off metabolic damage from excess sugar consumption

endogenous antioxidants

JOOVV: For A Limited Time Go To Joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

metabolic flexibility and the survival switch

seasonal weight

hibernation

how fructose can block fat burning 

the polyol pathway; turning glucose into fructose

AVALONX SERRAPEPTASE: Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist, And Use The Code Melanieavalon For 10% On Any Order At Avalonx.Us And MDlogichealth.Com!

Nature Wants Us to Be Fat: The Surprising Science Behind Why We Gain Weight and How We Can Prevent--and Reverse--It 

is whole fruit ok? 

how fiber factors in

low fructose diet

vitamin c 

oxidative stress

Unripened Fruit

AMPK, AMPD and Metformin

Our content does not constitute an attempt to practice medicine, and does not establish a doctor-patient relationship. Please consult a qualified health care provider for medical advice and answers to personal health questions.

TRANSCRIPT

Melanie Avalon: Welcome to Episode 273 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, biohacker and author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Cynthia Thurlow, Nurse Practitioner and author of Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging. For more on us, check out ifpodcast.com, melanieavalon.com, and cynthiathurlow.com. Please remember, the thoughts and opinions on this show do not constitute medical advice or treatment and no doctor-patient relationship is formed. So, pour yourself a mug of black coffee, a cup of tea, or even a glass of wine, if it's that time and get ready for The Intermittent Fasting Podcast.

Hi, friends. I'm about to tell you how you can get sugar free, nitrate free, heritage breed bacon for life, plus $10 off. Yes, free bacon for life, plus $10 off. We are so honored to be sponsored by ButcherBox. They make it so, so easy to get high-quality humanely raised meat that you can trust. They deliver 100% grass-fed, grass-finished beef, free range organic chicken, heritage breed pork, that's really hard to find, by the way, and wild caught sustainable and responsible seafood shipped directly to your door. When you become a member, you're joining a community focused on doing what's better for everyone. That includes caring about the lives of animals, the livelihoods of farmers, treating our planet with respect, and enjoying deliciously better meals together. There is a lot of confusion out there when it comes to transparency, regarding grazing practices, what is actually in our food, how animals are being treated. I did so much research on ButcherBox. You can actually check out my blog post all about it at melanieavalon.com/butcherbox. But I am so grateful for all of the information that I learned about their company. All of their beef is 100% grass-fed and grass-finished. That's really hard to find. They work personally with all the farmers to truly support the regenerative agriculture system. I also did an interview with Robb Wolf on my show, The Melanie Avalon Biohacking Podcast, all about the massive importance of supporting regenerative agriculture for the sustainability of not only ourselves, but the planet. This is so important to me. I'll put a link to that in the show notes. 

If you recently saw a documentary on Netflix called Seaspiracy, you might be a little bit nervous about eating seafood. Now, I understand why ButcherBox makes it so, so clear and important about how they work with the seafood industry. Everything is checked for transparency, for quality, and for sustainable raising practices. You want their seafood. The value is incredible, the average cost is actually less than $6 per meal, and it's so easy. Everything ships directly to your door. I am a huge steak lover. Every time I go to a restaurant, I usually order the steak. Oh, my goodness, the ButcherBox steaks are amazing. I remember the first time I had one and I just thought, “This is honestly one of the best steaks I've ever had in my entire life.” On top of that, did you know that the fatty acid profile of grass-fed, grass-finished steaks is much healthier for you than conventional steaks. And their bacon, for example is from pastured pork, and sugar and nitrate free. How hard is that to find? I'm super excited, because ButcherBox’s bacon for life is back and it's even better, because you get $10 off as well. Yep, right now, new members will get one pack of free bacon in every box for the life of your membership, plus $10 off when you sign up at butcherbox.com/ifpodcast. That's one pack of free bacon in every box for the rest of your life, plus $10 off. Just go to butcherbox.com/ifpodcast. And we'll put all this information in the show notes.

And one more thing before we jump in, are you fasting clean inside and out? When it comes to weight loss, we focus a lot on what and when we eat. It makes sense because these foods affect our hormones and how our bodies store and burn fat. But do you know what is possibly, one of the most influential factors in weight gain? It's not your food and it's not fasting, it's actually our skincare and makeup. As it turns out, Europe has banned over a thousand compounds found in conventional skincare and makeup in the US due to their toxicity. These include endocrine disrupters, which mess with your hormones, carcinogens linked to cancer, and obesogens, which literally can cause your body to store and gain weight. Basically, when we're using conventional skincare and makeup, we are giving these obesogenic compounds direct access to our bloodstream. And then in our bodies, studies have shown they do things like reduce our satiety hormones, increase our hunger hormones, make fat cells more likely to store fat, and more resistant to burning fat, and so much more. If you have stubborn fat, friends, your skincare and makeup maybe playing a role in that. Beyond weight gain and weight loss, these compounds have very detrimental effects on our health and they affect the health of our future generations. That's because ladies, when we have babies, a huge percent of those toxic compounds go through the placenta into the newborn. It is so, so shocking and the effects last four years. 

Conventional lipstick, for example, often test high in lead and the half-life of lead is up to 30 years. That means, when you put on some conventional lipstick, 30 years later, maybe half of that lead has left your bones. On top of that, there is essentially no regulation of these products on the shelves. That's why it's up to us to choose brands that are changing this. The brand that is working the hardest to do this is Beautycounter. They were founded on a mission to change this. Every single ingredient is extensively tested to be safe for your skin, so, you can truly feel good about what you put on. And friends, these products really, really work. They are incredible. They have counter time for anti-aging, counter match for normal skin, counter control for acne and oily prone, and counter start for sensitive. I use their Overnight Resurfacing Peel and vitamin C serum every single night of my life and their makeup is amazing. Check on my Instagram to see what it looks like. Tina Fey, even wore all Beautycounter makeup when she hosted The Golden Globes. So, yes, it is high-definition camera ready. They have so many other products, deodorant, shampoo and conditioner that I love, products for babies, and so much more. You can shop with us at beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. Also, make sure to get on my clean beauty email list. That's at melanieavalon.com/cleanbeauty. I give away a lot of free things on that list. So, definitely check it out. You can join me in my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. People share their experiences, ask questions, give product reviews, and I do a giveaway every single week in that group as well. 

And lastly, if you're thinking of making Clean Beauty and Safe Skincare, a part of your future like we have, we definitely recommend becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership. It is totally, completely worth it. So, again, to shop with us, go to beautycounter.com/melanieavalon or beautycounter.com/cynthiathurlow and use the coupon code, CLEANFORALL20 to get 20% off your first order. And we'll put all this information in the show notes. All right, now, back to the show.

Melanie Avalon: Hi, friends, welcome back to the show. I am so excited for you guys for our conversation today because this is a super special episode of The Intermittent Fasting Podcast. We very rarely have guests on this show. If we have a guest on the show, it's because you know that we really, really love the work, and the thoughts, and opinions, and knowledge, and science of the guests that we brought on. I am so honored to be here today with Rick Johnson. The backstory on this is, I was first exposed to Rick's work a few years ago. I heard him on Peter Attia’s podcast and you guys know that we love Peter Attia. I was fascinated because I personally am very fascinated with the role of fructose in our diets. I know that's a very granular thing to be obsessed with, but I was so excited that there was somebody else who was really looking at the science of fructose metabolism. And so, I got his first book, The Fat Switch, and then fast forward, I really, really wanted to interview him, and then I heard him again much more recently, again on Peter Attia’s podcast because he has a new book out called Nature Wants Us to Be Fat: The Surprising Science Behind Why We Gain Weight and How We Can Prevent--and Reverse--It. I was like, “I've got to book him for the show for the Melanie Avalon Biohacking Podcast. 

Then his people actually came to me, his publicist or PR people asking to come on the show. I was so, so excited. That episode, actually, as of our recording right now is actually airing today on the Biohacking Podcast. But when this comes out, that will have been a few weeks ago. But I just so enjoy that conversation and since then, Rick and I have been emailing, and diving deeper into the science of everything, and I just knew I had to bring him on this show to share all of his incredible work with you, guys. I'm really happy right now. Rick, thank you so much for coming on the show.

Richard Johnson: It's an absolute pleasure really. [laughs] 

Melanie Avalon: I was just telling you this offline, but for Cynthia Thurlow’s other podcasts for listeners, she also recently aired an episode with Rick and said it was her most downloaded episode of the year. She interviews a lot of heavy hitters. So, that's pretty cool. This content is definitely resonating with people. Rick, for people who are not familiar with you, there might be some people who have listened to your other episodes, but for those who are not, what is your story? You're currently a professor of medicine at the University of Colorado, but what led you to where you are today with your fascination with fructose and this thing called the survival switch, and obesity, and just everything?

Richard Johnson: I went to medical school, trained to be a physician, and did my specialty in kidney diseases as well as internal medicine. But from the very start, I always was very interested in the “why” not just how to manage a person, but why were they developing diabetes, why were they developing kidney disease? And so, I began my career quite a few years ago, where I was both a clinician, as well as a researcher. I’ve got a lot of funding from the National Institute of Health to help me along the way and over the last [unintelligible [00:11:08] years, I've been doing research. It started off in kidney disease and then I became interested in high blood pressure because high blood pressure is linked with the kidney. From there, I discovered that there was a substance in our blood called uric acid and that substance was very strongly associated with high blood pressure. We actually found evidence that it might actually play a role in high blood pressure. Big surprise and I just kept following my nose along the way to try to figure out what was this pathway and then pretty soon, I became interested in, “Well, okay, if uric acid is so important, what's driving the uric acid up in our population,” because there's a lot of people with high uric acids.

The classic teaching was, it was from eating purine-rich foods, because high uric acid is associated with a disease called gout. It's associated with drinking beer, and eating a lot of meats, and stuff. But there's another food that dries up uric acid and its sugar. Table sugar or high fructose corn syrup contains fructose. Fructose is a carbohydrate, it's sugar in fruit. But if you eat it, it will generate uric acid. And particularly, if you eat a lot of it, you can really raise the uric acid inside your body and it turns out that that led me to some big discoveries, because the uric acid turned out to have a role in driving obesity and diabetes, and it led me to realize that fructose was really a culprit. Then from there, I started studying fructose and I found out that it wasn't just the fructose that we eat, but that our bodies can make fructose. This opened the door for what might be causing the whole obesity epidemic.

It was a long story. It took me everywhere. I did studies in hibernating animals, and I did studies in people, I did studies in genetically modified mice, and I did studies in indigenous tribes living in the jungle, I even did studies where we resurrected extinct genes. So, I've been around and really, it has been an adventure story, Melanie.

Melanie Avalon: I love it so much. And actually, to that point, your book, one of the things I really love about it is it reads like an adventure story, especially the very beginning where you're talking about, it's like a mystery of why did we become fat like as a society? You talk about really fascinating things that happen in animals. Could you tell listeners about the hummingbird for example?

Richard Johnson: Yeah. [laughs] Oh, we think that the hummingbird is this magnificent bird that's has the fastest metabolism of perhaps all birds. I think that it's flaps its wings, what, 250 times a minute. It has an incredible metabolism. You would think that that bird must be the healthiest bird in the world. But it lives off nectar and nectar is really sugar water, and that contains a lot of fructose. It contains fructose and glucose. When that hummingbird drinks this nectar, it is getting a very large amount of sugar. What happens is, during the day, that sugar is so strong that the little bird becomes diabetic. Its blood sugars go up to 500. Perhaps, the fattest liver of any bird, turns like glistening white. And so, by the end of the day, It's fat and diabetic. Then during the night, it will rest, and it will burn off the fat and the glucose, and in the morning it will be back to its normal state. And so, it's like intermittent fasting, [laughs] because a little bird gets really fat and then he fasts through the night. Interestingly, if they burn off all the fat and the carbs, then the he’ll go into torpor, which is a hibernation state, where they drop their metabolism, drop their blood temperature and all that, their body temperature. So, yeah. No, it's a very interesting bird.

Melanie Avalon: With those huge spikes in blood sugar, which that blew my mind when I first read that, is it getting the effects of glycated hemoglobin? Does it have an HbA1c and things like that? How does it long term, how is it handling those spikes?

Richard Johnson: Well, one of the interesting things is, first off, there's not a lot of studies of hummingbirds long term. But what has been done suggest that they actually do all right, so that they're-- What happens is that they have such good mitochondria and they have this very good protective system to help protect the mitochondria from getting permanently damaged. They pair to not get diabetic complications. They've been able to survive diabetes without the complications. Again, no we can talk about what drives diabetic complications and all that kind of thing, but it's really interesting that these guys will raise their blood sugars to over 500. These are very high blood sugar levels, but they seem to be relatively protected. Although, I think more studies really need to be done, but the initial reports suggest that they're pretty protected even though they're very diabetic.

Melanie Avalon: Does that insinuate? This is completely theoretical and not real life at all. But if we could have a metabolism fast enough to burn off everything that we are eating or if we could literally exercise until we exercised off all of our excess calories that we could mitigate damage ourselves?

Richard Johnson: I think that that's true. There are people who have super mitochondria. There really are. There are people running around they tend to be the super athletes. Studies done in these super athletes, these professional athletes, like the guys that win the Tour de France, they have such wonderful mitochondria that they have what we call metabolic flexibility, where they can burn carbs and fat, intermittently going back and forth very freely without any problems. One of the things they have is they have a very high antioxidant system in their mitochondria that helps protect the mitochondria from damage. I have a friend who coaches in the Tour de France and he points out that a lot of these super athletes appear to eat sugar without a problem. Now, my belief is that if they pounded themselves with sugar and fructose that they would get into trouble over time but it is interesting. 

There's this naked mole rat. This is a little guy who burrows into the sand in South Africa. They live in these burrows where there's almost no oxygen, even though they have very low oxygen system. There's low oxygen there and it would normally kill most animals. They've developed a system where they can survive in that low oxygen state. One way they do that is they produce huge amounts of antioxidants in their mitochondria that protect them from the effects of hypoxia. It's interesting. There's a fructose story there, too, but I should probably bring that up later. But basically, if you can have super mitochondria, you can survive under a lot of stress and you can survive in the presence of sugar. I should say that these little naked mole rats make fructose to survive, but they don't suffer the consequences of the fructose because of this high-powered antioxidant system they develop.

Melanie Avalon: To clarify for listeners, because I think a lot of people hear antioxidants and they think exogenous antioxidants. So, they think antioxidants from fruits and vegetables and things like that. But these are antioxidants that our bodies are creating endogenously, right?

Richard Johnson: That's right. They're making it themselves. There's one called Nrf2. This antioxidant is strongly associated with living longer. I have a friend at the Karolinska, who studies this antioxidant. He can show that in many, many species that if you can maintain a high Nrf2 you can live longer. It's actually linked with sugar because if you eat sugar, you induce oxidative stress to the mitochondria. You can accelerate aging in animals by giving them fructose. And so, fructose does this by making the mitochondria put them under stress. That hummingbird is creating oxidative stress in his mitochondria and that would normally be associated with developing obesity and all these complications that would persist. But by keeping the antioxidant system high, which the hummingbird has genetically, by having that very high antioxidant system, he can protect his mitochondria. The super athlete has this incredible antioxidant system and the naked mole rat, which lives 30 times longer than a normal rat. It lives 30 years, whereas a normal rat lives two years. It's thought to be because of this Nrf2, this antioxidant system. 

But it's interesting, this Nrf2 system can be knocked down. One way, it can be knocked down is with fructose. I keep thinking, “Well, the hummingbird is eating all the sugar, he's got this high Nrf2. Can over time this be weathered down and knocked down?” That's why I'd like to see more studies done in the hummingbird and in the naked mole rat where they have this Nrf2. Because we know that if you take human cells and you treat them with fructose, the Nrf2 is knocked down and you get this oxidative stress, and you can accelerate aging. And so, it's a really interesting thing. The antioxidants in the mitochondria are really important at protecting the mitochondria from the complications of obesity, diabetes, and aging. And fructose is usually something that makes things worse and things like these antioxidants can protect against fructose. Some animals that are eating a lot of fructose or making a lot of fructose seem to do well, because they have a high level of these antioxidants. But like us, normally, we don't. But if you're super human-- [laughs]

Melanie Avalon: Jealous. 

Richard Johnson: Yeah, I’m jealous of those guys, too.

Hi, friends. I often get asked, “What is my favorite bio hack or what do I use every single day?” Something I use every single day of my life is red and near infrared therapy and I'm about to tell you how to get a discount on my favorite brand for that. For years now, I've been using Joovv light therapy devices to achieve all the benefits of red light and near infrared therapy. Red light is a type of light naturally found in the rising and setting Sun. I use it to help sync my circadian rhythm and also to combat the overwhelming abundance of stimulating blue light that we are exposed to every single day. Yes, my apartment looks like the red-light district at night, but I cannot express enough how crucial it is for helping me wind down, support my mood, sleep well. It is just so, so amazing. Red light can also help with your skin health, give you a healthy glow. Near infrared has so many benefits including targeted pain relief and muscle recovery. The reason red and near infrared light can seemingly be magic and fix so many things is because they actually affect how your cells mitochondria generate energy. When your cells are properly generating energy, well, everything just basically works better. 

The reason I recommend Joovv is because they are amazing quality products. They source from only the highest quality materials, including medical grade components, and they have undergone third party testing, and receive safety marks from nationally recognized testing laboratories. This gives you the safest, most reliable product possible. Other companies claim to be medical grade, but they fall short with no independent safety testing or medical grade components making it a no brainer for me to recommend Joovv as my go to red light therapy company. Joovv offers several different size options. They have a wireless handheld device called the Joovv Go that I use to target specific areas of my body and it is also amazing for travel. Yes, it is TSA friendly. I go to a wellness spa for cryotherapy almost every single day and they have Joovv devices there. I'm just so grateful that I have it in my own home, so, I can use it every single day from the comfort of home. No membership anywhere required. You can check out all of the Joovv today. And for a limited time, Joovv is offering our listeners an exclusive discount on your first order. Just go to joovv.com/ifpodcast and use the coupon code IFPODCAST. Again, that's JOOVV dotcom forward slash IFPODCAST for a discount on your first order. Pick up a Joovv today. Some exclusions do apply. joovv.com/ifpodcast and join me in using one of the most incredible things for your health and wellness that you will ever bring into your life. I promise, I love Joovv. And I'll put all this information in the show notes. All right, now, back to the show.

Melanie Avalon: I'm so glad you're using these words, stress and you dropped in the word, metabolic flexibility, which is something that our listeners love hearing about and we talk about a lot in this show. I think a foundational question here. Because you're talking about activating the stressed out state and how that's a problem, what is that survival switch and how is it different from being in the survival state of fasting, which has a lot of benefits to it?

Richard Johnson: The very first major discovery we had was that there seemed to be this substance in our blood called uric acid. This uric acid is generated from foods we eat, but we also can make it. This uric acid, when it gets high, that can be associated with a disease called gout. You can get these uric acid can crystallize at high concentration and these crystals end up in the joints, particularly the big toe, and you get gout. That was noted a long time ago that gout is associated with being overweight or obese, and it's also associated with being diabetic, and it's associated with all kinds of conditions that aren't particularly what we would like to be. For a long time, it was thought that, “Oh, people who are overweight or obese are at increased risk for getting gout” and it's really the obesity that's leading to the gout. But in fact, our work started to suggest that uric acid might actually have a role in driving obesity. We found evidence that people with high uric acids where risk of developing obesity in and of developing diabetes. And so, that led us to try to understand what could raise the uric acid and it took us to fructose.

Fructose, when you give fructose to an animal, normally, animals regulate their weight just beautifully. If you overfeed it or it will gain weight, but then you stop over feeding, it will come back to normal weight. If you fast, it will lose weight because you're taking away its calories. But then as soon as you let it eat again, it will go right back to the weight it wants to be. Most animals want to carry a little bit of fat, but not a lot of fat.

Melanie Avalon: Can I ask you a quick question?

Richard Johnson: Yeah. 

Melanie Avalon: Doesn't it go back to the weight that correlates to the season?

Richard Johnson: Yes, yes, it does. Usually, in the spring animals and the summer animals will really regulate their weight well. But as winter comes and food becomes less available, animals will start to increase their weight in the fall, in preparation for winter. The biggest case, of course, are animals that hibernate. There're some animals that they can't find enough food during the winter that they will actually hibernate and they will drop the metabolism, they'll go into a burrow or something, and they'll just basically go to sleep, and drop their heart rate, they drop their temperatures, and they won't eat, they won't drink, they won't pee, anything like that for maybe three to six months. The bear can hibernate for four to six months. During that time, it's not eating or peeing or anything. It lives off its fat during that time. The fat doesn't just provide energy, but when the fat’s broken down, it produces water. There's this really interesting thing. We don't think of fat as a source of water. Normally, most of us don't. But fat is a source of calories and it's a source of water. When you eat food, you're making calories you eat are turned into energy. Most of the time, we think of energy as this thing, ATP is what we call it in science. This is basically a chemical that activates processes and generates energy. This ATP is what we usually call our immediate energy.

But there's also a stored energy and that's fat. When you're eating calories, they usually are either burned as active calories like ATP or they're stored as fat, and then the fat is later burned to generate energy when you're not eating any foods, so the fat becomes that source of energy, when there's no food around. These animals, all animals like to have a little fat because they want-- In case, if something happens and they don't get any food for a while, they can basically generate the energy they need from their fat, but they also generate water from their fat. Fat becomes a survival tool for animals in the wild. It led to my Nature Wants Us to Be Fat, because these animals would like, for example, if you're a burden, you're going to migrate 10,000 kilometers. You want to have enough fat, so that you can burn it, and get the water and energy you need, so, you don't have to try to find food when you're halfway over the ocean. Because if you're a land bird, that's not a good thing to be.

Anyway, so, what happens is, these animals will gain weight dramatically in preparation. This is the cool. They do it in preparation before they know there's no food around. Beginning in the fall, for example, the bear will start gaining eight to 10 pounds a day and it does that by eating huge amounts of food. Normally, I told you, animals regulate their weight. They have a sensation of when they're full and so, they won't keep eating. But they lose that sensation of fullness in the fall. Suddenly, they will keep eating, and they will eat huge amounts of food, and they'll get fat, and then they'll survive with that fat when they hibernate. So, there's a little bit of evidence that people also tend to gain weight during the winter months, as you probably have read. 

Melanie Avalon: So, do we gain during the winter, do we gain leading up to the winter?

Richard Johnson: Well, that's a good question. For the animals that hibernate, they will keep gaining until they actually hibernate. When they hibernate, they're obviously not eating it off. We tend to keep eating into the winter, [chuckles] as well as during winter. Actually, we're pretty much eating too much all the time if you look and so the problem is, it says, if we have activated this switch to gain weight in a 24/7 pattern. But this was one of the questions that we had. What happened is, we realized that these animals were gaining weight in the fall and they weren't just gaining weight, they were eating more, they were hungry, they were thirsty, and they also became insulin resistant. They develop these features, we call metabolic syndrome. They're foraging for food, and they're eating too much, and they're getting fatty liver, and the fats are going up in their blood, as well as in their adipose tissue, and they're gain insulin resistant, and we go, “Oh, my God, this is what we call abnormal. This is what we call metabolic syndrome.” We consider this almost a disease among people, right? But if you're a bear, this is normal. This is what you want. It's a survival pathway, because if they didn't do this, they might get into trouble. 

When there's no food around, it's late then to store fat. We realized that this whole process was really a survival switch, and that it was turned on, and it was something that animals do to help them survive. This was the first big discovery that really in our group was that there was the survival switch. The metabolic syndrome, what we call-- When people come in and they go, “Yeah, my hemoglobin A1C is high, my blood sugar's a little high, I've got high triglycerides in my blood.” This is part of a syndrome. You have activated the switch. That's what's going on. This was the first big thing. Then the question you had was, “Why would insulin resistance be a survival switch? Why would that be part of a survival switch?” It causes diabetes. Diabetes is associated with increased risk for death. Why would an animal want to be prediabetic? The interesting part is that the brain loves glucose. It’s his favorite fuel, okay? Glucose is its favorite fuel. It will use ketones as well, but it loves glucose, says, it's ideal fuel. Glucose is regulated by insulin and Insulin is the hormone that goes up in our blood, drives glucose into tissues. There're certain tissues that are particularly insulin responsive and the big one is muscle. When you become insulin resistant, there's less glucose going into the muscle, so the glucose begins to collect in the blood and the brain doesn't really require insulin at least for much of the brain. 

It's a way of shunting the glucose from the muscle to the brain. If the animal could think about survival, if it really could do that, it would want to have the glucose that it has be preferentially use for its thinking, rather than for its muscle, because if you can't think, you're not going to do well out in the wild. Insulin resistance is really a way to help an animal when it does not have enough food around to help preserve the glucose, mainly for brain function. There's a scientist that I've worked with who studied starvation and things like that, and when you starve, not only does your insulin levels go down, but you become relatively insulin resistant as well. It's all meant to help when there's no food around, you want that glucose primarily to go to the brain.

Melanie Avalon: The big paradigm shift here are also a debate in a chicken and egg question is, it sounds some people will say, you become overweight or obese and that causes metabolic syndrome. But this sounds more metabolic syndrome has a purpose to make us overweight and obese?

Richard Johnson: Yeah, metabolic syndrome is really another name for a collection of signs and symptoms to help you survive a period of time when there's no food. If you want to maximize how to help yourself during a time when there's no food, you want to have the metabolic syndrome because you want to be insulin resistant, you want to have high fats, and your blood and your liver and everywhere, so that you have enough fuel to survive when there's no food around.

Melanie Avalon: So, what's happening when we practice intermittent fasting? Is that stimulating all of this because we're in a “starvation state” during the fast?

Richard Johnson: Okay. When you quit eating, you're actually not necessarily activating the switch right away. Because you have fat already, everybody has some fat. When you fast, you begin by burning the glycogen and fat that you have. A normal animal, if it starts fasting will not activate the switch. When the animal that gets really fat like the bear, and he gets really fat, and then winter comes and there's no food around, and that's usually the time when they can't find any more food, they'll hibernate, and they switch into a fat, they switch into a burning phase. First, they burn the glycogen, which is the carb stores, and they disappear within a day or two, and then they will burn the fat, and it is a very healthy thing. They're not foraging, they're not hungry, they're sleeping and they're just burning the fat, and they get rid of the fat. Then in the spring, they may have just a tiny bit of fat left and many times, they won't have any fat left and that may actually help stimulate them to wake up actually. Then they wake up and they're back to normal.

When you're intermittent fasting, most people who are intermittent fasting have some fat stores and they have-- Everybody has some fat stores and some glycogen, right? If you intermittent fast, you are burning the glycogen and you're burning the fat. When you're burning the glycogen and fat, everything is fine. You're not in trouble, you're not in trouble. But as soon as the fat burns away, then you know what they have to burn? The protein. That's the only thing. Yeah, the muscle. One of the first things that's released is uric acid and that is like an alarm signal and it turns on the switch and they start foraging, they’re looking for food, and they're desperate. But now, they've turned on the switch in a situation where there really are starving. They've done studies with penguins. The emperor penguin is this magnificent bird. It is. I want to go to Antarctica and see one of these guys. Apparently, there was a penguin that was six feet tall ones.

Melanie Avalon: I was going to say, how tall are they? Yeah, they're tall.

Richard Johnson: These are four feet, I think three to four feet or so three feet, maybe. But there was a penguin that was six feet. That's the penguin, but it's extinct now, unfortunately. The colossus penguin. But anyway, the emperor penguin is this huge penguin and it will get fat in the Antarctic before it nests. The emperor is one of the few birds that nest during the winter. It's nesting during the winter in the Antarctic. It has to store-- It does the same thing. It gets usually fat. Usually fat. It almost doubles its weight. Its liver gets really fat. Birds get particularly get fatty liver. Then it wattles in inland and then the male actually does the nesting, because the male is a bigger bird, so, it can carry more fat. And so, it can survive longer than the female in the winter. When it's nesting, the male will sit on the egg because it knows that it may not that winter’s a long time down there and it can take a while. It wants to have enough fat and so, the male has more fat, so it can last longer. But sometimes, the male doesn't have enough fat. If it runs out of its fat while it's burning the fat, it completely feels good. It just sits there, it's not in distress, same thing is true with people who are fasting. 

If you're just burning the carbs and the fat, it's generally not a stressful situation from the standpoint of survival. But once the muscle starts breaking down, the penguin will desert. It will leave the egg, and will try desperately to get back to the coast to get some food, and it will start making sounds, calling sounds and foraging. It's like a stressful period. If it doesn't get food, it will die. What's interesting is that what heralds, that shift is a rise in uric acid because uric acid is released and is generated when muscles breaking down. That was actually a clue to us that uric acid might be a survival factor and so, it was interesting that fructose raised uric acid. Then we started studying, “Well, why does fructose raise the uric acid and what's the uric acid doing?” What we found is that when you give fructose to an animal, it creates a pseudo starvation state. What happens is, when you eat fructose, inside the cell, the fructose causes this drop in phosphate. And phosphates are critical for energy production, phosphate is part of ATP. ATP, the P part is a phosphate. The way the ATP works is that it donates a phosphate to generate and drive chemical reactions. That's how energy is activated really. What happens is when you eat fructose, there's this acute fall in phosphate inside the cell. When that happens, the ATP levels fall. The breakdown of ATP gets turned into uric acid and then the uric acid keeps the energy levels in the cell low for a prolonged period of time and it does so by causing oxidative stress to those energy factories that are making ATP. It causes oxidative stress to these mitochondria and that suppresses the mitochondrial function. 

Now, again, if you're a super athlete, that's not going to happen. Your mitochondria are strong enough to weather. Your hummingbird, it's not going to happen. Because at least, acutely, you can weather that storm. But for most of us, when that mitochondrial stress occurs, it suppresses the mitochondria, keeps the ATP levels low, and that activates an alarm system. Basically, the animal thinks to itself, “You know what, my energy levels are low. I'm in trouble.” Normally, if my energy levels are low, my fats going to kick in and start being broken down to provide that missing energy. But what fructose does is, it blocks the burning of the fat at the same time. It's suppressing the ability to break down the fat. When the ATP levels fall, the only way to replenish it is to eat more. You can't use that fat, because the fructose is blocking your ability to burn the fat. And so, what happens is you become hungry and you start eating more, and then more food comes in, and again you've got this shunt going on. More of the calories are going to stored fat rather than to ATP. The ATP levels will continue to stay low for a while, and then eventually, you'll correct it, but at the expense of eating a lot more food. So, it's this brilliant system. 

Basically, when you eat fructose, your body thinks it's starving. It will continue to stimulate processes to store fat, to become insulin resistant, but you're actually not starving. It is pseudo starvation. Because you have fat on board and it's only getting bigger, more from this. It's a way to get the animal instead of regulating this weight so perfectly, I'm going to stay skinny. Now, suddenly, you're gaining weight. When people are young, when you're 20 years old, and you're out running on the beach, and you have all the energy in the world, you can drink that soft drink and it's not going to really have a big effect. You're not going to see sudden weight change or anything like that because your mitochondria are pretty healthy and it takes repeated insults, repeated times. But in this world, where 70% of processed food has sugar in it, where soft drinks are everywhere, where they're putting all this kind of foods around, and this high fructose corn syrup is being added to everything. We're being hit hard ,15%, 20% of our diet is from these added sugars. And so, we're chronically activating this switch. Some of us do it better than others or worst-- [laughs] look at it. And so, some people gain weight a little bit easier than others, some are still doing pretty well, and you can battle it by exercise, you can battle it by willpower, but this is a biologic process. So, it's hard to have the willpower chronically when there's a biologic process saying that you're hungry, this looks good. So, this is what's going on.

Melanie Avalon: Basically, when we're eating sugar, and high fructose corn syrup, and things like that, it's really ironic. Because we're taking in calories, we're taking in energy, but it's stopping our body from actually burning energy, so, our body needs to eat more, which is ironic.

Richard Johnson: That's exactly how it works. It's like tricking the system and it turns out when we started studying this, we realized that glucose is actually, really there as an immediate fuel. It's really meant to make ATP, it's not meant to really be a storage mechanism. Fructose, though, is the carb that's really trying to aim at storing energy, as opposed to immediately using energy. Now, I know you're going to say, well, but I know that eating bread, and rice, and potatoes, and French fries, and they don't have fructose in them, but they're fatty. We know that from low-carb diets how powerful bad carbs can be. This was a challenge. This was a challenge to me. Because when I was originally doing this work, and we were giving fructose to animals, and they developed metabolic syndrome, and then we could see that a lot of animals were eating fructose to create metabolic syndrome as a survival mechanism, it seemed the answer was going to be easy. We just had to avoid foods with fructose. I even wrote a book, The Sugar Fix back in 2008. It was one of the first books to say, “The problem is fructose. It's not anything else.” I had a lot of people write me, email me, tell me, “Oh, my God, when I quit eating sugar, I lost 25 pounds, I feel great. Thank you so much.” 

Then of course, you can't completely stop eating sugar. I don't recommend that either. It's a birthday or something, I'll eat sugar. Anyway, the idea was to really limit sugar. Then I had these people contacting me and saying, “I'm sure sugar is important, but I have to cut out all carbs. I really have to cut out starch and especially, high glycemic carbs,” carbs that release glucose into the blood like potatoes, rice, cereal, chips. I knew that they were right because I knew that when I ate bread it seemed like I would gain weight. There's not a lot of sugar in bread, there's a little. Then I said, “Okay, well, buy bread that doesn't have much sugar at all.” I found that I still. There was something about bread and me that was making me gain weight. Then we started trying to figure it out and then we had this really major insight. It was not our discovery. People had already discovered that the body can make fructose. There's only one way you can only make fructose from glucose. There's a specific enzyme. Normally, that enzyme is pretty quiet. When we're born, we do not really have that enzyme anywhere, except in certain regions of our kidney. But otherwise, it's really not around and we call it the polyol pathway. But it was known. Gosh, it was known when I was in medical school that in diabetes, the body can make fructose and this polyol pathway is turned on. It was known that once you become diabetic, you can make fructose even if you're not eating it.

There are studies showing that particularly when diabetes was out of control that you can have high fructose levels in your blood, in your urine, and we've confirmed that sense. Then the question was, “Well, how does it work?” It turns out that the enzyme that makes fructose gets turned on when you're starving, it makes sense. It gets turned on when you're dehydrated. That makes sense because fructose will make fat, fat can be a source of water and it can be turned on when glucose levels in the blood are high in diabetes. That made sense because when the blood glucose goes up, it makes the blood concentrated and what happens is, it makes you thirsty. So. it's another way to create dehydration. We said, “Uh-huh. But what about high glycemic carbs?” When you eat bread, the glucose gets released. We call it high glycemic carbs, because certain foods, when you eat it, the glucose level will go up in the blood right after you eat it. Let's say, you have a blood sugar of 80, and you eat some bread, your blood sugar might go up to 120. It may just go up that fast with just eating a slice or two of bread. That's because when the bread is broken down, it releases glucose very rapidly, and some of that gets into the blood, and it makes the blood concentration go up. So, it's a transient or temporary diabetic state. You're not diabetic when you eat bread, but your glucose shoots up. And so, you have transient, temporary high glucose or hyperglycemia and that turns out to be enough to activate the switch. 

What we found was that high glycemic carbs get turned into fructose in the body. If you block that and we did it in laboratory mice, but we did it beautifully and knocked it out. When that happens, those animals are incredibly protected. They don't get fatty liver, they don't get insulin resistance, they still gain a little weight, but it's a healthy obesity. It is driven by insulin, but it's not actually the mechanism that where you get fatty liver and insulin resistance. it is not from the effects of insulin itself. It's from the fructose. And so, it turns out that high glycemic carbs are bad. They're really bad, but it isn't really just from stimulating insulin. It is because they get turned into fructose. And now, there was just recently a study showing that when you eat glucose, you’re making fructose in the body. It's been shown in humans now. I'm feeling pretty confident that this is a major mechanism. That's why low-carb diets are so great because you are restricting sugar, which is fructose, which contains fructose. You're restricting high fructose corn syrup, but you're also restricting high glycemic carbs. You're restricting the main way that the body can make fructose because it uses glucose. If you restrict foods that make a lot of glucose it's going to work. So, that was like, “Wow, that explains the low-carb diet.”

Hi, friends, I'm about to tell you how to get 10% off my supplement line, serrapeptase and magnesium are here. You guys have been waiting, I've been waiting. This is honestly just so, so thrilling. I am very suspicious of the supplement industry. So, I took it upon myself to start making my own versions of everything that I currently take, so that I can know that I am putting the very best into my body that is the AvalonX line. Our first supplement was a crowd favorite with everybody, serrapeptase. Oh, my goodness, this supplement is a game changer. It is a proteolytic enzyme created by the Japanese silkworm. When you take it in the fasted state, it actually goes into your bloodstream and breaks down problematic proteins in your body. It can really address anything that is caused by your body reacting to problematic proteins. I started taking it originally years ago, because it clears my sinuses like none other, it also can reduce brain fog. Studies and personal experience have shown it can break down fibroids, enhance wound healing, even reduce cholesterol, and break down amyloid plaque, and potentially, provide pain relieving benefits. This supplement works with your body to make you function better on so many levels. I don't know where I would be without it. 

My version is the best on the market. I created it with my partner MD Logic, and it is tested multiple times for purity, potency, and to make sure the enzyme is active. It's free of all common allergens like wheat, gluten, soy, shellfish, nuts, dairy, even rice, which is very, very common in a lot of supplements. We have to use a special process to make it, so that it doesn't have the common problematic fillers that are in every single serrapeptase supplement on the market that I looked at. It comes in a glass bottle to help prevent leaching of plastics into our bodies and the environment. This is the serrapeptase you want. And my second supplement, magnesium is the magnesium you want. Magnesium is involved in over 300 enzymatic processes in the body. Basically, everything that you do requires magnesium. We are so deficient in magnesium today due to our modern farming practices and our stressful lifestyles. There are multiple types of magnesium. That's why my magnesium spectrum eight has eight forms of magnesium to make sure you're getting the magnesium that you need. It comes with cofactors including methylated b6, yes, methylated and chelated manganese, yes, chelated to help you absorb the magnesium. My magnesium three and eight nightcap will be coming soon as well. That will be if you want to enhance your magnesium for special sleep and relaxation benefits. And of course, everything I said about testing allergens and the glass bottle applies to all of my supplements. 

If you want to feel good about what you're putting in your body, AvalonX is the answer. I am so excited that I was able to make it. You can get 10% off all of my supplements at avalonx.us and 15% off with subscriptions. The coupon code, MELANIEAVALON will also get you 10% off any supplements made by my partner MD Logic Health. So, to shop with me, go to avalon.us and use the coupon code, MELANIEAVALON or you can look at everything MD Logic Health at melanieavalon.com/mdlogic. And to stay up to date on all the specials sales and upcoming supplements, definitely get on my email list. That's at avalonx.us/emaillist. So, again, avalonx.us with the coupon code, MELANIEAVALON. And we'll put all this information in the show notes. All right, now, back to the show. 

Melanie Avalon: For listeners, you'll have to get Nature Wants Us to Be Fat, because he goes deep into all of the technicalities of all these studies that you've conducted and they're just really, really fascinating. And so, just for listeners so they can get the full resource. So, big question. Fructose, we keep saying fructose sugar, high fructose corn syrup. Does this apply to whole fruits as well?

Richard Johnson: Oh, great question. Again, we're studying this right and I'm going, “Oh, my gosh, if this is correct, then I shouldn't be eating an apple or a banana.” I love fruit and fruit is healthy. There are 200 papers out there plus it shows that if you're eating natural fruits, you tend to do well. But there's an interesting thing. It was noted 20 years ago by the pediatricians that fruit juice was not the same as natural fruits. They actually did studies and they found that if children drink fruit juice that that was associated with obesity. The pediatric societies came out and said, “Hey, you got to limit how much fruit juice you're drinking, especially if you're giving it to children,” because they can get obesity from it. It can stunt growth, it can do all kinds of things, but particularly, the obesity and the diabetes were strongly associated with fruit juice. What was the difference? Well, it turns out that when you eat a natural fruit, one fruit has 46 grams of fructose, typically, some have a little bit more, but that's much less than drinking a soft drink that has 30 grams of fructose. We're talking a big difference in the amount. So, that's one.

The second thing is, when you eat a natural fruit, there's fiber in it and fiber slows the absorption of the fructose. That's important because the way the fructose drops the energy in the cell it is like a chemical reaction. It's not based on just the amount. it's based on the concentration. If the fructose hits there and it's at a high concentration, the energy falls a lot and the switch is turned on a lot. But if you get only a little bit of fructose there, the energy just falls a little bit and it's not going to create the same thing. It's going to be a much milder activation of the switch. The switch is really like a dimmer. It's not like on and off. When you drink a soft drink, you're drinking a ton of fructose, 30 grams, and you're drinking it in about five minutes or less. Some people just guzzle it. You get this big wave of fructose that hits the liver and big activation switch. But when you eat fruit, especially you're eating it with a meal, and there's all this fiber, and everything slows the absorption, you're only eating a small amount, you don't get the same dose. You don't get the same concentration.

There's another thing. The intestinal lining can inactivate about four or five grams of fructose. It turns out that the fructose in vegetables gets inactivated. You can eat vegetables. Sweet potatoes can have a little bit of fructose in it, but it's not going to make you fat because your intestines going to inactivate it. Now, if you coat it with brown sugar. [laughs] There's a way to beat everything. You can make it worse. Just keep in mind. It's like the dose and the dose is what happens in the wild. The bear doesn't eat 10 berries and then a nut. It's eating thousands of berries and grapes at a time and I mean it. There're some studies that show that they can eat 10,000 berries in 24 hours. [laughs] But anyway, so fruit. We decided to do a study in people. It's good enough to talk about this, but let's do it. We gave overweight ladies, a low-fructose diet and that included low fruit, low everything man. Anything that had fructose in it, it was limited. One group got that, but one group got the low-fructose diet, but we added back natural fruits. There really wasn't a low-fructose diet. It was really a low-added sugar diet, but they couldn't drink fruit juice and stuff like that. It turned out that even though the people got natural fruits, they still improved their metabolic syndrome and they tolerated it better. They felt better on the diet. So, I think that natural fruits are good. I think it's possible to overdo it. If you're eating a huge amount of fruit in front of the TV, you're probably going to activate the switch.

Melanie Avalon: Would a fourth factor in the fruit be how we talk about-- how we lost our ability to synthesize vitamin C, actually as a mechanism to encourage weight gain. So, would the vitamin C and the fruit also help mitigate the effects?

Richard Johnson: Yes. There's this really interesting thing. We have to take vitamins. When we take a vitamin is because we used to make that stuff, but we don't make it anymore. Vitamin C, humans, our ancestors could make vitamin C, but we lost the ability to make that vitamin C. We have to get vitamin C or we can get a disease called scurvy. One of the great discoveries was James Lind, surgeon, who was on a ship and all these guys were getting this terrible aching joints, and bleeding joints, and bleeding gums. They had scurvy and he gave them some lemons, and oranges, and he could cure it. Later figured out it was the vitamin C. So, people go, “Why would we have lost vitamins?” The ability to make vitamin C, there's no advantage to being vitamin C deficient. In fact, you're going to get scurvy. Why would that happen? And so, it's been a mystery why we would lose vitamin C. One of the things about vitamin C is, it's an antioxidant. Antioxidants are supposed to be good. So, why would you lose an antioxidant? You would think you might live shorter if you didn't have that or shorter time. It's been a mystery. But when we were studying this, we realized that vitamin C turns out to be an antioxidant and it's involved in the survival switch. Remember how I told you how mitochondria that are really healthy have a lot of antioxidant activity? They can block the oxidative stress induced by fructose. 

When you give fructose to an animal, you create this oxidative stress to the mitochondria and it's driven by the uric acid. But the oxidative stress suppresses the mitochondria and reduces the amount of ATP produced, so that the energy that comes in gets converted to fat. What happens is, it's a way to suppress the oxidative stress, suppresses the ATP production, so that the calories are converted to stored energy instead of to instant energy. Oxidative stress is actually a survival tool to prepare you for winter. It's actually to help you store fat. It turns out that the mutation for vitamin C occurred at the time of the dinosaur extinction. This huge asteroid, Chicxulub it was called, came sailing in from the heavens, and smashed the earth, and caused a major extinction. All the dinosaurs basically died except for the birds, which was sort of a dinosaur like thing. It creamed the animals and the primates got creamed. There were a lot of primates. At least, there were some primates we think genetically. But for some reason, some of those primates survived and it turns out, it was that most of those primates, the lemurs also survived, and they did not get this mutation. But all the other primates, there was a common ancestor. And they somehow this one guy lost his vitamin C through a mutation and it provided a survival advantage. The survival advantage was that it led to a greater oxidative stress to those mitochondria from just even a small amount of fructose. And so, it allowed you to store fat more easily. 

The way we prove that was we took mice, and we worked with them, and we got genetically altered mice that were vitamin C deficient just like we are. You have to keep them on a low dose of vitamin C or they will get scurvy. Now, we had him on a low dose of vitamin C just to keep them from getting scurvy. But now, we give one group a high dose of vitamin C and the other group we give a low dose. We have two groups of mice. We have a mouse group that has a high vitamin C and we have a group that has a low vitamin C, and then we gave them sugar. Actually, we gave them high fructose corn syrup. Both groups, all animals love high fructose corn syrup. We put it in their drinking water, they were happy, and it activated their switch, and they started eating more. They don't just get the calories from the sugar water, they’d become hungry and they eat more chow and they eat more, they got fatty liver, they became prediabetic, the whole bit. But the group that had the low amount of vitamin C got a lot more fatter. They got almost 40% more fat. And so, we could show that the vitamin C mutation could help these animals survive when there wasn't much-- It would help them survive if there wasn't much fructose around. But if we give them more fructose, then they actually become fatter than their controls, because they're getting more damage to their mitochondria, so they can survive. 

It turns out that fruit, when fruit is first immature, the seeds are immature. The fruit falls, there's going to be no germination, the seeds aren't going to be able to make a new fruit tree. It's high in vitamin C at that time. Animals won't gain much fat by eating it. They tend not to go after immature fruit. But as the fruit ripens, the sugar content goes up and the vitamin C content goes down. It's almost like the plant knows that the plant wants the fruit to be eaten when the seeds are mature, so that it can promote a new tree. By making the fruit ripe would load vitamin C, the animals know that they're going to get more fat from eating it. They learned this evolutionarily. It isn't they know this, but this brought into the evolution of how these animals work. What's happened is vitamin C, when the fruit that-- we tend to like fruit that's less mature, we like the tart fruits, we like the fruits that don't have as much sugar. We don't like the right mushy fruits that a lot of animals would go after. We want it when it's tart, high in vitamin C. When we're eating natural fruits, the fruit has fiber, and potassium, and vitamin C, and all these things help counter. So, that is why natural fruits are good, even though they contain fructose. But things like fruit juices and sugar, why they're so effective at activating the switch.

Melanie Avalon: Well, again, listeners, if you get Nature Wants Us to Be Fat, it has an entire outline of a diet to follow, because I bet listeners are probably thinking, “Oh, no. What do I eat now?” It's a really, really helpful resource. I want to be really respectful of your time. Can I ask you one last super granular question that I apologize in advance to listeners, because it's going to be so granular? [chuckles] It's based off of what we were talking about recently with some email exchanges. 

Richard Johnson: Yes, please go ahead. 

Melanie Avalon: I had asked Rick about fructose’s effect on AMPK in the cells. And listeners might actually be familiar with AMPK, because we do talk about it a lot on the show is a pathway that's activated from fasting, and how it creates a lot of benefits in the fasted state by signaling the need for energy, and a lot of benefits from that. Okay, so, here's my question. In one of the studies that I was reading and I sent you the quote from it last night, but it was saying that “fructose actually activates both AMPK in the cell and AMPD2 specifically, which is like counteracts AMPK and has the opposite effect of AMPK. I'm probably completely bastardizing this but in layman's terms, that was my takeaway is that it actually stops fat burning and counteracts the beneficial effects of AMPK. Okay, here's my question. One of the other studies you had sent me was talk-- No, I think it was the same study. It was talking about metformin, and how metformin can actually block AMPD2. So, if you were to and this is hypothetical, and I don't even know if this practically could happen. But if you took in fructose, and then you took in a compound like metformin, and if you could block AMPD2, would that actually be all beneficial then, because then you'd be stimulating AMPK from the fructose, but you wouldn't be getting the AMPD2, so, you'd be just getting the benefits?

Richard Johnson: Well, this is pretty heavy question, but let me just say a few things and I'll try to get to that answer. I think you're onto something. But let me just begin by saying that AMPK is this wonderful pathway that when you activate it, it burns fat, and it keeps glucose levels down, and it gets inhibited in diabetes, and it's inhibited. Our group show that it's inhibited by AMPD and by uric acid and AMPD is the enzyme that makes uric acid in the fructose pathway. So, it turns out that fructose activates AMPD and AMPD makes uric acid and they counter the effects of AMPK. There's this ying-yang, where AMPK is considered the good guy and AMPD is what drives fat. And so, we would love to make an AMPD inhibitor and metformin is a weak one. If metformin it stimulates AMPK and it weakly inhibits AMPD and this is probably one reason why metformin has been found to be so beneficial. But if it could really knock down AMPD big time, it could be a huge winner. When we knock down AMPD, we can even cure genetically induced obesity. It's just amazing. We can block addiction for sugar and it's just a very powerful pathway.

Melanie Avalon: In theory, there could be a drug that could do that. If that happened and then you took in fructose, would you get benefits then, because you stimulate AMPK, still? 

Richard Johnson: You probably would, you would because one thing that can stimulate AMPK is a drop in energy in the cell. Fructose drops the energy in the cell, but then the AMPD pathway and the uric acid generated inhibits the AMPK. When you give fructose, you can show that AMPK goes up to some extent, it's actually induced, but then it's inhibited by the uric acid and the AMPD. The net effect is that AMPK is kept low. Now, in a true starvation state, the AMPK can override the AMPD. If you're in a true starvation state where there's no fat around and things like that, you are very minimal. AMPK will be activated. But anyway, you're right. These two players, AMPD and AMPK, the balance of that is so important in intermittent fasting, and low-carb diets, and anything. AMPK should be viewed as pretty much a good guy and AMPD is its evil counterpart, [laughs] unless you're preparing for starvation, then you want that AMPD man.

Melanie Avalon: Well, thank you for entertaining that. I was reading all the studies and I was like, “I have to ask,” and apologies to listeners for the random rabbit hole. Well, this has been so amazing. We only barely touched on just a tiny bit of everything that's in your book. Listeners, go get Nature Wants Us to Be Fat. It's amazing. You will learn so many things. And Rick, I can't thank you enough for your work. I'm so excited to see what the future holds with all of your studies. Are you writing another book right now?

Richard Johnson: I'm thinking of writing another book. I haven't started, yet, but I'm very interested in writing a book about discovery processes just because I've been involved in quite a few and like, what's the art of discovery? Because it's interesting how there're different approaches to discovering things in it.

Melanie Avalon: Does it often start with asking why, like, you were saying in the beginning?

Richard Johnson: Yeah. Well, one thing that's for sure involved with almost every discovery process is just you got to be passionate and curious. For sure, those two are characteristics that are constantly seen. But there's a lot of serendipity and all kinds of things that are involved. There're certain tricks that I think can help that I might be able to write about them. Not necessarily that I have done, but that other people that I've seen others do, too, because I've been doing research since the mid-80s. And so, I've been around and I've been around some wonderful people, I've seen Nobel laureates, talked to them, and over the years, I've just been very curious to know, “What is it? Why did that guy discover that?” I'm interested in, “What was the thinking that led to that?” Not so much what the science of the discovery is, but like, “How did he figure that out and what was the technique?” So, I'm interested in that part.

Melanie Avalon: I love that. I really hope you write that because I would just eat that up. I would love to bring you on in the future if you do and talk all about that. Well, thank you so much. This has been absolutely wonderful. Again, listeners, there will be a full transcript in the show notes because I know we went deep into everything. But this has been so amazing and hopefully, we can talk again in the future.

Richard Johnson: Thank you, Melanie. That was just wonderful. Your knowledge is so strong. It's just really wonderful talking to you.

Melanie Avalon: Oh, thank you. You're amazing and I will talk to you soon. Bye.

Richard Johnson: Bye. 

Melanie Avalon: Thank you so much for listening to the Intermittent Fasting Podcast. Please remember, everything we discussed on this show does not constitute medical advice and no patient-doctor relationship is formed. If you enjoyed the show, please consider writing your review on iTunes. We couldn't do this without our amazing team. Administration by Sharon Merriman, editing by Podcast Doctors, show notes and artwork by Brianna Joyner, transcripts by SpeechDocs, and original theme composed by Leland Cox and recomposed by Steve Saunders. See you next week.

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Cynthia: cynthiathurlow.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Jan 18

Episode 248: SIBO, Antibiotics, Insulin, Wine, Alcohol Metabolism, Fatty Liver, Whole Foods Diet, And More!

Intermittent Fasting

Welcome to Episode 248 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Gin Stephens, author of Delay, Don't Deny: Living An Intermittent Fasting Lifestyle

Today's episode of The Intermittent Fasting Podcast is brought to you by:

LMNT: For Fasting Or Low-Carb Diets Electrolytes Are Key For Relieving Hunger, Cramps, Headaches, Tiredness, And Dizziness. With No Sugar, Artificial Ingredients, Coloring, And Only 2 Grams Of Carbs Per Packet, Try LMNT For Complete And Total Hydration. For A Limited Time Go To drinklmnt.com/ifpodcast To Get A Sample Pack For Only The Price Of Shipping!!

BEAUTY AND THE BROTH: Support Your Health With Delicious USDA Organic Beauty & The Broth Bone Broth! It's Shelf Stable With No Preservatives, And No Salt Added. Choose Grass Fed, Grass Finished Beef, Or Free Range, Anti-Biotic And Hormone Free Chicken, Shipped Straight To Your Door! The Concentrated Packets Are 8x Stronger Than Any Cup Of Broth: Simply Reconstitute With 8 Ounces Of Hot Water. They’re Convenient To Take Anywhere On The Go, Especially Travel! Go To thebeautyandthebroth.com To Get 15% Off Any Order With The Code MelanieAvalon!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

LMNT: For A Limited Time Go Tdrinklmnt.com/ifpodcast To Get A Sample Pack For Only The Price Of Shipping!! Learn All About Electrolytes From Our Great Interview With Robb Wolf!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At MelanieAvalon.com/beautycounter, And Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: melanieavalon.com/beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

The Melanie Avalon Podcast Episode #74 - Benjamin Bikman, Ph.D.

Go To audible.com/ifpodcast Or Text IFPODCAST To 500500 For A 30 Day Free Trial, Including A Free Audiobook!

Go To thebeautyandthebroth.com To Get 15% Off Any Order With The Code MelanieAvalon! Learn about the wonderful benefits of bone broth by listening to this episode with the creator melissa Boloña!

Listener Q&A: Keri - Seeking Patience and Answers. My Saga and road to IF

The Melanie Avalon Biohacking Podcast Episode #117 - Tim Spector

The Delay, Don't Deny Community

Stay Up To Date With All The News About Melanie's New Serrapeptase Supplement At melanieavalon.com/avalonx Or Head Straight Over To Avalonx.Us To Place Your Order Now!

This Naked Mind: Control Alcohol, Find Freedom, Discover Happiness, and Change Your Life

DRY FARM WINES: Natural, Organic, Low Alcohol, Low Sugar Wines, Paleo And Keto Friendly! Go To dryfarmwines.com/ifpodcast To Get A Bottle For A Penny!

Episode 125: Roxi

Episode 50: Renee and Joel

Episode 170: Kristi Osborn

TRANSCRIPT

Melanie Avalon: Welcome to Episode 248 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Gin Stephens, author of Fast. Feast. Repeat.: The Comprehensive Guide to Delay, Don't Deny Intermittent Fasting. For more on us, check out ifpodcast.com, melanieavalon.com, and ginstephens.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment. So, pour yourself a cup of black coffee, a mug of tea, or even a glass of wine, if it's that time, and get ready for The Intermittent Fasting Podcast. 

Hi, friends. I'm about to tell you how you can get free electrolyte supplements, some of which are clean, fast approved, all developed by none other than Robb Wolf. Have you been struggling to feel good with low carb, paleo, keto, or fasting? Have you heard of something called the keto flu? Here's the thing. The keto flu is not actually a condition. Nope. Keto flu just refers to a bundle of symptoms. Headaches, fatigue, muscle cramps, and insomnia that people experience in the early stages of keto dieting. Here's what's going on.  

When you eat a low-carb diet, your insulin levels drop. Low insulin in turn lowers the production of the hormone aldosterone. Now aldosterone is made in the kidneys and it helps you retain sodium. So, low aldosterone on a keto diet makes you lose sodium at a rapid rate. Even if you are consciously consuming electrolytes, you might not be getting enough. In particular, you need electrolytes, especially, sodium and potassium, in order for nerve impulses to properly fire. Robb Wolf, who as you guys know is my hero in the holistic health world worked with the guys at Ketogains to get the exact formulation for electrolyte supplements to formulate LMNT Recharge, so you can maintain ketosis and feel your best. LMNT Recharge has no sugar, no coloring, no artificial ingredients, no junk. They're used by three Navy SEALs teams. They are the official hydration partner to Team USA weightlifting, they're used by multiple NFL teams, and so much more. 

Guess what? We worked out an exclusive deal for The Intermittent Fasting Podcast listeners only. Guys, this is huge. They weren't going to do a deal, I begged them, here we are. You can get a free LMNT sampler pack. We're not talking a discount, we're talking free. Completely free. You only pay $5 for shipping. If you don't love it, they will even refund you the $5 for shipping. I'm not kidding. The sample pack includes eight packets of LMNT, two Citrus, two Raspberry, two Orange, and two Raw Unflavored. The Raw Unflavored ones are the ones that are safe for your clean fast and the other ones you can have in your eating window. Word on the street is the citrus flavor makes an amazing margarita, by the way.  

I am loving LMNT and I think you guys will, too. Again, this is completely free. You have nothing to lose. Just go to drinklmnt.com/ifpodcast. That's D-R-I-N-K-L-M-N-T dotcom forward slash IF Podcast. And I'll put all this information in the show notes.  

One more thing before you jump in. Are you fasting clean inside and out? Did you know that one of our largest exposures to toxic compounds, including endocrine disrupters, which mess with our hormones, obesogens which literally cause our body to store and gain weight, as well as carcinogens linked to cancer is actually through our skincare? Europe has banned thousands of these compounds for being toxic, and the US has only banned around 10. It's honestly shocking. So, when you're putting on your conventional skincare makeup, you're likely putting toxic compounds directly into your body. These compounds can make you feel bad, can make it really hard to lose weight, can affect your hormones, your mood, your health. And ladies, if you're thinking of having kids, when you have a child, these compounds actually go directly through the placenta into the newborn. That means your skincare makeup that you're putting on today actually affects the health of future generations.  

Did you know that conventional lipstick for example often test high for lead and the half-life of lead can be up to 30 years in your bones? That means when you put on your lipstick, 30 years later, half of that lead might still be in your body. Thankfully, there's an easy, easy solution to this. There's a company called Beautycounter and they were founded on a mission to change this. Every single ingredient and their products are extensively tested to be safe for your skin. You can actually feel good about what you put on and on top of that, their products actually work that's because they're not “all natural.” They actually combine the best of both worlds, both synthetic and natural ingredients to create products that actually support the health of your skin and make your skin look amazing. They have skincare lines for all your skin types, deodorant, shampoo and conditioner that I love, anti-aging and brightening peels, and vitamin C serums, and incredible makeup. If you see my makeup on Instagram, that's all Beautycounter. You can shop with us at melanieavalon.com/beautycounter 

And if you're thinking of making safe skincare a part of your future like we have, we definitely suggest becoming a band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders, and a welcome gift that is worth way more than the price of the yearlong membership, totally completely worth it. Also, definitely join my clean beauty email list at melanieavalon.com/cleanbeauty, I give away a lot of free things on that list and join me on my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. I do a weekly giveaway every single week for Beautycounter, people share their experience and product reviews, and so much more. And again, the link to shop with us is melanieavalon.com/beautycounter. All right, now, enjoy the show. 

Melanie Avalon: Hi, everybody and welcome. This is Episode number 248 of the Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with, Gin Stephens.  

Gin Stephens: Hi, everybody.  

Melanie Avalon: How are you today, Gin?  

Gin Stephens: Well, I am fabulous. It is January 2nd and I was late putting up my Christmas decorations this year. So, I took them down earlier than usual. [laughs]  

Melanie Avalon: I was going to ask you. I've been stressing about the proper time to take them down. I was going to take them down today.  

Gin Stephens: Well, I follow the, like, take them down to the 12 days of Christmas kind of a thing. So, therefore, January 5th would be the official or 6th depending on what you count as day one, I don't know. But right around January 5th or 6th.  

Melanie Avalon: Wait, I thought the 12 days of Christmas ended on Christmas.  

Gin Stephens: No, that's when it begins.  

Melanie Avalon: What? Are you sure?  

Gin Stephens: Yeah. There's the season in the Christian faith called epiphany. That's the name of the season. If you look up epiphany. 

Melanie Avalon: I will say, listeners, I feel good. I typed in when are the-- It is the 4th search. People are wondering.  

Gin Stephens: [laughs]  

Melanie Avalon: Do you want to know what the first three are?  

Gin Stephens: What do you mean? The first three what?  

Melanie Avalon: What people are searching for when they search for? When are the- 

Gin Stephens: Yeah.  

Melanie Avalon: -college football playoffs, Winter Olympics, Grammys, 12 Days of Christmas.  

Gin Stephens: Love it. 

Melanie Avalon: Then, Oscars. Whoa.  

Gin Stephens: What? 

Melanie Avalon: Mind blown. I always thought the 12 days of Christmas ended on Christmas.  

Gin Stephens: Yeah. See, Gin knows her stuff about stuff. [laughs] So, officially, I always keep it up till later. But I've got so much going on this week. Yesterday, I was like, I'll just take down a few things and leave up the trees. And then, I was in such a roll and I was already all dirty from taking dusty stuff and whatever, and then, I'm like, "I'm just doing it." So, I did it. So, my house is un-Christmased, whatever. un-Christmased. That is a hard word to say. [laughs]  

Melanie Avalon: I feel so much better now. I was stressing about-- Because this is my first time having my own tree, and I was like, "When do I take it down?" Okay, I thought I was late.  

Gin Stephens: No. I was just early and was a little sad. But like I said, I was on a roll, so, I did it, and here we are 2022. Officially, our first time talking in the New Year.  

Melanie Avalon: I know. A question for you. I asked you this before, but you sent me a Christmas tree that is in a pot. What do you think will happen if I keep it in the pot? Will it overtake the container? What I was asking you before is, they say that goldfish, and I don't know if this is true, because I just briefly googled it, and I think it might not be true. But I'd always heard that goldfish grow to the size of their container. So, that's why like when you have a goldfish at home, it's small, but if the goldfish in ponds are big.  

Gin Stephens: Yeah, I don't know the answer to either of those questions because I am the last person to ask about how to keep a plant alive. So, Chad does all keeping plants alive and I keep other things alive, like, children and cats. [laughs] He keeps plants alive. Here's what I always do. I keep it in the pot until it dies, and then I throw it away. Now, when I was a teacher, one year Chad gave me this beautiful orchid on the first day of school, and I kept it in my classroom, and it was beautiful, and then it died. There was another teacher at my school who saves things. 

Melanie Avalon: Wait, you know about orchids?  

Gin Stephens: I don't know anything about orchids, but I know that my friend, who was like, "I can save that." So, I gave it to her instead of throwing it away.  

Melanie Avalon: Fun fact because Gin and I have the same agent. All the people that I worked with there, so, the main agent and then two assistants, they're actually agents now, I sent them an orchid plant, three of them. It was so perfect. They came in three different colors. So, I was like, they can pick whatever color they want. Are you ready? So, the orchid blooms once a year. It "dies," but it comes back. So, it might not have been dead.  

Gin Stephens: Well, I gave it to her. Normally, I just would throw them away, and then I felt bad. Here's my whole rationalizing this. I felt bad. I'm like, "This plant died and then then I had to throw it away, and that's like a waste of a good plant." Then I'm like, "Wait a minute. Anytime we cut flowers, since you cut flowers, they die and you throw them away."  

Melanie Avalon: And it probably wasn't even dead.  

Gin Stephens: I don't know. Hopefully, she revived it.  

Melanie Avalon: The thing is, I had never realized this. So, I put everywhere in the note. I explain this because I didn't want them to think it died, because they were dyed. 

Gin Stephens: Brittle looking?  

Melanie Avalon: Well, the flowers were dyed. D-Y. Dyed colors. It said that it would die and then it would come back, but it would be its normal orchid color. So, then, I sent them a follow up email and I was like, "Maybe this is common knowledge. But just FYI about those orchids."  

Gin Stephens: No, no, when I think an orchid is dead, it's not that the flower falls off. It's that the entire stem is now brown and twiggy looking. That's what I call it, it's dead now. Not just because the flowers fell off. I mean, I do know if it's still green just because the flower fell off, that doesn't mean it's dead. But once the stem would get twiggy, actually, I do know my friend did save it. When I said, I hope she saved it, she did. She told me she did.  

Melanie Avalon: Speaking of plants, this is actually so perfect, unplanned. I interviewed Farmer Lee Jones last week.  

Gin Stephens: His book is beautiful.  

Melanie Avalon: Oh, my goodness, Gin. So, up until this point, so, I've had over a hundred something guests on the Melanie Avalon Biohacking Podcast. Up until this point, everybody's been really incredible, really amazing, a lot of people are really passionate, but when I'd interviewed Wim Hof, he was just like another level of passion. Everybody was like at this kind of hit this glass ceiling of passion, and then he was just lightyears ahead. Farmer Lee Jones is on the Wim Hof spectrum of passion. He was yelling at the microphone. I was like, "Oh, my goodness." He was incredible. I have never felt so inspired to support regenerative agriculture, and bring back nutrient density, and revive our soil, and take charge of our health through growing better food. This man is incredible. He's so amazing. So, for listeners when that episode comes out, definitely check it out. The entire time I was just smiling. I was watching myself having the interview and I was just smiling. Can you imagine if everybody had that type of energy, what type of world we would live in?  

Gin Stephens: Oh, I know.  

Melanie Avalon: So, it was amazing.  

Gin Stephens: That's great. Oh, I'm actually, finally listening to Why We Get Sick 

Melanie Avalon: Oh, Dr. Gregor.  

Gin Stephens: No, no. Benjamin Bikman.  

Melanie Avalon: Oh, that's how not to die.  

Gin Stephens: You had Benjamin Bikman on your podcast, right?  

Melanie Avalon: Yes. Oh, I loved that. Oh, he's amazing.  

Gin Stephens: Yeah. Spoiler alert, insulin. [laughs] But it is everything I already thought and he's saying it, I mean I haven't gotten all the way in but so far, the beginning talking about hyperinsulinemia. 

Melanie Avalon: [sighs] I remember when I was doing all that and I was like, "Gin, read this book." It's basically like the insulin manifesto.  

Gin Stephens: It really, really is. What inspired me to go ahead and get it as someone in my community said that it was available included through Audible Plus, with their new Audible Plus Catalog where you don't have to use a credit for it. You just can listen. 

Melanie Avalon: I haven't used that yet.  

Gin Stephens: What Audible Plus?  

Melanie Avalon: Mm-mm. 

Gin Stephens: I've always just had Audible and didn't ever join it. I just had it as my audiobook library and I would just buy a book. I didn't buy very many. But now, I'm driving to the beach and back-- 

Melanie Avalon: Sorry to interrupt. So, this is different then, because I have a membership with credits.  

Gin Stephens: This is the Plus membership. They have a new membership level, the Audible Plus. 

Melanie Avalon: And this book is on it?  

Gin Stephens: And you still get a credit, but you also have more things that you can listen to that are included that don't take credits and this is one of them. It's got good stuff in there. It's not just like, stuff you don't want to listen to that you can listen to for free. No, it's stuff you do want to listen to and it's included and you don't have to use a credit. So, that finally got me to pull the trigger on getting Audible as a membership, especially, now that I'm driving to the beach so much and in the sauna I can listen. So, I'm finally listening to something. 

Melanie Avalon: I'm obsessed with Audible. Actually, for listeners, because right now, as of the time of recording I'm not sure if they're still sponsoring the show. We were actually booked on inventory but I'm so passionate about them that might see if I can keep them in. So, if we do have a code for them right now, because this airs in January. I'll put in the show notes. We probably do.  

Gin Stephens: They do sponsor IF Stories. I just read an ad for them today, but yeah.  

Melanie Avalon: There probably is still an offer at the link, listeners, if you go to audible.com/ifpodcast or text IF PODCAST to 500-500. Well, I'm glad, Gin that you are on the Audible train with me now. Audible is like my life.  

Gin Stephens: It's funny as an author of course. As soon as our books come out, you find like a typo, right? You're like, "Oh, they're--" I was just looking through Clean(ish) and they've already been printed, and of course, by this time, they come out, everybody will have them already, because we're past the date that will be released when this podcast releases. But as soon as I got my copy of the final version, I look, there's some kind of weird typo in one of the reflect and take action sections, and it's clearly just an extra character got inserted, because it's not a letter of the alphabet in the middle of a word, like an and or something. I don’t know.  

In the middle of the word, someone just leaned on their typewriter, I don't know, or their keyboard. I'm like, "Well, there's one right there." But that was not in the original document. But typos get in there all throughout the way. But I was listening to Why We Get Sick today, and an entire paragraph was repeated. I swear, I just heard that exact-- 

Melanie Avalon: In the audiobook.  

Gin Stephens: Yes.  

Melanie Avalon: That's funny.  

Gin Stephens: It exactly is in there twice. So, I'm like, I don't care how many people are part of the process, things happen. It makes you feel better when you see in other places, because you want your work to be perfect, but perfection is an illusion.  

Melanie Avalon: Yeah, and I told you this before on the show, but when my narrator recorded my audiobook, she did find an error in mine, but she said every single book she's ever recorded has always had an error.  

Gin Stephens: Yeah. Also, one of the websites that I mentioned as a resource no longer exists and I hate that. Because it existed all the way through, and even when we checked it, and all the way through all the final, and then, all of a sudden, it's not there anymore. I'm like, "Great." [laughs] So, people would be like, "I can't find that website." I'm just waiting for the emails to start. Yes, it doesn't exist anymore. Sorry. The internet is elite living thing and it changes.  

Hi friends, I'm about to tell you how you can get 15% off of my favorite bone broth, which is an incredible way to open your eating window. I've been talking about the incredible health effects of bone broth for years. Bone broth is so nourishing for our body. It's rich in collagen, which can really support your gut health, your skin, curb cravings, boost your energy and your immunity, but there are a lot of brands out there, a lot of them have ingredients that I don't like, and making it yourself can also be very time consuming. That's why I am thrilled about Beauty & the Broth. So, Beauty & the Broth was created by Melissa Bolona. She's an incredible actress and entrepreneur. I've had her on the Melanie Avalon Biohacking Podcast. So, I'll put a link to that in the show notes. But Melissa started Beauty & the Broth after she realized the profound effect that bone broth was having on her own health specifically, gut issues, and its ability to give her radiant skin perfect for the camera. She founded Beauty & the Broth which hits everything I could want in bone broth. It uses 100% whole organic ingredients. Yes, it is certified USDA organic. It is one of the only few bone broth companies in the entire US that has a USDA certification for organic bone broth. It has no artificial flavors, no preservatives, no phthalates, no sugar, and something that I love no salt. 

Friends even other bone broth that I really love always have salt added. This doesn't. Her bone broths are made from grass-fed ranch raised beef and vegetarian-fed free range chicken bones from Certified Humane USDA Organic Farms and all certified organic vegetables are used in the broth as well. There're no antibiotics, no hormones, only the good stuff. Here's the super cool thing about Beauty & the Broth. It can be a little bit of a hassle to transport bone broth. It's heavy, you have to keep it frozen. Guess what? Beauty & the Broth comes in shelf stable packets with no preservatives that you keep at room temperature and they are in concentrated form. That means that you add back water to reconstitute and you can make it any strength that you like. They're single servings, so you can take them with you on the go and even on the plane, as yes, they are three ounces and they're delicious. Oh, my goodness, friends, they will just make you light up. They're honestly one of the most amazing things I've ever tasted. So, if you've been looking to finally jump on the bone broth train, do it now and do it with Beauty & the Broth. And Melissa has an amazing offer just for our listeners. You can go to thebeautyandthebroth.com or melanieavalon.com/broth and use the coupon code MELANIEAVALON to get 15% off. That's thebeautyandthebroth.com with the coupon code, MELANIEAVALON for 15% off. All of the listeners who have tried it, ever since I aired my episode with Melissa have talked about how much they love it. It is so delicious. You guys will definitely love it. So, definitely check that out.  

By the way, bone broth does break your fast. So, this is something that you want to have in your eating window. In fact, it's an amazing way to open your eating window because when you're in that fasted state, when you take in bone broth as the first thing, all of those rich nutrients and collagen go straight to your gut, help heal your gut, help with leaky gut, help digestive issues. And again, you can go to thebeautyandthebroth.com and use the coupon code, MELANIEAVALON for 15% off. I'll put all this information in the show notes. All right, now back to the show.  

Melanie Avalon: Shall we jump into everything for today?  

Gin Stephens: Yep, let's get started.  

Melanie Avalon: All right. So, to start things off, we have a very long question. It's from Carrie. Carrie, I cut down your question a lot. But it has a lot of good stuff in it, and a lot of good questions, and a lot of stuff to discuss. So, I thought we could just tackle it. This question comes from Carrie. The subject is: "Seeking patient answers, my saga and road to IF." Carrie says, "Hey, Melanie and Gin, I'm 46 and I started IF-ing two and a half months ago to lose weight. I haven't lost a pound yet nor an inch. Clothes still fit the same too. But I do love the convenience of it and the way I feel while I am fasting, energy, clarity, productivity. I clean fast. I was pretty sure drinking black coffee and giving up my Coffee-mate would cause certain death and it still hasn't. I haven't read any of your books but I did just start What When Wine this week. I chose that one because my story is very similar to Melanie's. So, I went with that one first in hopes of finding help.  

In May 2013, I had my appendix out. A couple of weeks later I got a sinus infection and they put me on, I'm thinking it's an antibiotic, which wrecked my gut bad. I was also nursing our third kid. The doctor said, I should do the BRAT diet which is Bananas, Rice, Applesauce and Toast. A week or two later, I got a positive C. diff test, more antibiotics, it worked. The C. diff was gone and eventually, I felt like myself again. Over a year later, I was training for another half marathon and doing daily HIIT for training. I was tracking calories and MyFitnessPal, and I never want to do that again. I lost 15 pounds which was the rest of my baby weight and I was very happy. But while the weight was coming off other things were starting. Anxiety, panic attacks, brain fog and hives. If I bumped my arm or leg on an edge or the counter or something that scratched it, I would end up with hives. In hindsight I think all the training and running exacerbated gut problems from all the antibiotics, but I have no proof.  

By the end of the summer, I gained 40 pounds. In spring, 2016, a chiropractor who does kinesiology put me on herbs for a liver parasite and liver virus. I added essential oils and that helped not needing Zyrtec. In 2017, she said she started a, it is a name brand 'Weight Loss Drink' thing. She says, eventually, the brain fog and anxiety cleared and I lost 15 pounds, but I plateaued and quit those. In 2019, I gained the 15 pounds back even though I ate very healthy 80% to 90% of the time. June 2020, a naturopathic practitioner put me on some remedies from Europe to support my organs. My once very poor digestion has improved, but it still has its poor movements. I did a parasite detox remedy and a heavy metal detox. I had my fillings replaced. Believe it or not, I had tiny pieces of metal coming out of my skin. I would be skeptical if I hadn't lived it. All of my traditional blood tests are always normal. A few elimination diets, food tests, which change every time, my thyroid appears fine. Now, I'm contemplating a SIBO test. It's like throwing noodles against the wall and waiting for something to stick. There's a reason I'm going through this, I just haven't discovered it yet.  

I did start that 'Weight Loss Drink' company thing again a couple of months ago because it worked the first time until it didn't. Now, it's almost 2022 and I still have 40 pounds. If not for your podcast, I'm sure, I'd have jumped ship by now. But you two keep me afloat in this sea of confusion. I fast a minimum of 16 hours, sometimes, up to 20 to 21. Eat later in the day, so I can eat with the family at night. IF worked for me in all the ways, except the one that outward shows every day and my clothes size, clothes comfort, self-esteem etc. I have three active kids and I cannot keep up with them at this size. I'm 5'4" and I currently weigh 175 pounds on a small frame. I spent so much time researching and going down rabbit holes. For exercise, I love walking and yoga. I don't do it regularly because it's not helping. I used to focus on 10,000 steps a day, but I've lost my motivation and discipline. One of the reasons I can't lose weight is also probably because I'm stressed.  

I also love wine and beer. Beer for socializing and I'm very good at it. I do try to get organic wines, I'm anxious to get to that part of the book that discusses it. I admittedly drink too much alcohol. It's how I deal with stress. I drink nearly a gallon of water daily. A couple of random things to share, I started serrapeptase a while back not for anything specific, but to see if something happened, I wouldn't have thought of. The verdict is still out on that. I did the ZOE program. While interesting, the foods still require tracking and I really don't want to track anything, and maybe, I misunderstood the program, but healthy foods were what was encouraged and less healthy were not. They seemed geared towards plant based and I'm not plant based. I was born to eat meat as well." 

Gin Stephens: That actually is the point of ZOE is teaching you what is healthy for your body so they're going to give those higher scores. That's the point. They are encouraging you to eat what will help your microbiome be healthy. They don't want you to eliminate plants, though. They're not like, "No, don't eat any meat." We're also not trying to get a score of a one hundred. So, I think that's where a lot of people get confused when they do ZOE, because they're not trying to teach you, only eat these foods that give your body a hundred, a score of hundred and don't eat anything else. It's wanting you to live in the real world by encouraging you to emphasize certain foods and de-emphasize other ones, if that makes sense.  

Melanie Avalon: I'm very, very impressed with their-- 

Gin Stephens: Support.  

Melanie Avalon: Yeah. You're connected with somebody who can answer your questions, and I've been drilling them on some of the questions I have about some of the foods in the app, and they've been very good at getting me really detailed answers. I do agree that I think it is very plant based. Some of it, I think is a little bit off with the meat and the seafood just as far as some of the things that it recommends. But in general, the concept that it's addressing is processing fats versus glucose like carbs and that effect. Then, the foods have to do with effects they've seen in the gut microbiome. I think it's a really helpful app and it's really interesting seeing feedback, especially, my Facebook group. Some people are like, "This is a game changer, this completely helped me break through a plateau, I feel better." For some people, it tells them what they feel like they already knew, and then, some people, especially people I think who are more low carb parts of it don't quite resonate. But either way, regardless the information that you get with the CGM and the gut microbiome test, there's a lot to learn there. So, it's really cool. I'll put a link in the show notes. I interviewed Tim Spector, the founder. So, that was a really, really cool conversation.  

Gin Stephens: Oh, and I'm talking to him. When this comes out, what, is this comes out on the 17th? I'm talking to him on the 19th. We're doing a webinar in my community. We've never actually talked, even though, he wrote the foreword to Clean(ish), we've never actually talked. So, we're going to do a webinar only available for members of the Delay, Don't Deny Community. Go to ginstephens.com/community. You still have time to get there. But the replay will be there in the community as well. That's the only place it will be available. But they're very gut focused. So, that is why they're encouraging the foods that will feed your gut really, really well.  

Melanie Avalon: Exactly. Just we're talking about little pieces as we go. I want to say briefly about the serrapeptase. So that's the supplement that we've been talking about for a while on this show and I finally developed my own, which is very exciting, and it's a proteolytic enzyme created by the Japanese silkworm, and when you take it in fasted state, it actually goes into your bloodstream and it breaks down potentially problematic proteins. So, things that your body might be reacting to, it can help address. So, inflammation, allergies, it can clear your sinuses. Things on the backburner that you might not quite notice but you need to be on it long-term to possibly see difference in your bloodwork would be things like it can break down fatty deposits, and it may reduce cholesterol, it just has a myriad of potential benefits, wound healing.  

It's really interesting to see because so many people in my audience have been getting it, and some people go to it with a very specific goal like, "I want to clear my sinuses," and people have really been seeing that. Some people are more like Carrie, where they're not quite sure what they're taking it for. But I just know for me personally, I think it has a very just general synergistic helpful effect on the body like fasting does in a way. So, if you'd like to get your own, it's at avalonx.us. 

Gin Stephens: All right, well, if we're going back, I have one more thing that I highlighted that was farther back. The part about alcohol and she said, "I admittedly drink too much alcohol." and it's how she deals with stress. I'm going to just come right out and say, Melanie and I have a different recommendation when it comes to how much alcohol might support weight loss are affect it negatively, and I think a lot of it is your own bio individuality. But for me, alcohol, when I was trying to lose weight absolutely stalled my weight loss. Like the period of time when I was trying to get to my goal weight, I didn't have alcohol for about 10 weeks at all, and I really focused on eating real foods. I didn't count fat grams, I didn't count carbs, I didn't count calories. I just didn't eat ultra-processed foods. I didn't drink alcohol. I lost two pounds a week. My body did so much better. Over the holidays, yes, I'm still drinking Dry Farm Wines. Yes, I love it. But my body doesn't feel it's best, even if I drink too much Dry Farm Wine. So, to feel my best, I'm better with zero alcohol, am I going to be alcohol free for the rest of my life? No. But if I wanted to lose weight and I knew I was-- If I actually said the sentence, "I admittedly drink too much alcohol." I would really start there.  

If you're worried like, "Oh, my gosh, I can't stop drinking alcohol, I just can't. How am I going to have fun?" Well, that's really when you need to start looking at how much you're drinking. And that's where I would recommend the book This Naked Mind. Annie Grace is the author, and I read it, and I was like, "Wow." Because I always have this, like you said, beers for socializing. I almost like that, too. I was like, "If I get together with my college friends, we're going to be drinking. That's what we do. We always have." So, the first time we got together, I was having a month where I wasn't drinking at all, and I was like, "Okay, I'm not going to tell them till we get there." It sounds like, they're going to be like, I'm not even coming or whatever and then when I got there and I'm like, "I'm not drinking, surprise." They're like, "Oh, okay, that's weird but that's fine." So, I was the designated driver, I had just as much fun, I socialized great, and I felt great the next day. So, I just really want you to-- Like I said, This Naked Mind, consider that book. It really will make you think about your alcohol consumption even if you like me decide you're not going to be alcohol free. But if you feel like you're drinking too much, I would not hesitate to read this immediately. Sorry, I had to pop that in there.  

Melanie Avalon: No, no, no. I'm really excited for her to get to my section on the book on alcohol and I agree. I think it's super context dependent on two things. Before that, I think there is something different between having what a person would consider minimal or moderate alcohol and trying to lose weight by adjusting it compared to knowing that you're probably overdrinking and wanting to lose weight. Like that's two different situations in my head. As far as the context, I think, people can be very different in how they metabolize alcohol. And then, also, I think the context of the diet that you're having it with is huge. So, for example, like for Gin, it sounds like for you, you would rather cut out the alcohol, that's an extreme approach to the alcohol compared to a more extreme approach to the food. 

Gin Stephens: Well, for me, I learned through the DNA testing that my body metabolizes alcohol slowly. Some people metabolize caffeine slowly, I don't. But my body does metabolize alcohol slowly. So, my liver has to work on the alcohol like, we had that breathalyzer that would test your ketones, I actually was using that for a long time, I don't know about a year ago or a little before a year ago. When I would drink, it would vastly affect the amount of ketones I would produce the next day. To the point like, it would take me a while to get it. My liver was busy processing alcohol for a long time is what I'm saying. So, it really affected my body. If I want to lose fat, my liver needs to not be busy processing alcohol.  

Melanie Avalon: Yeah. I guess, what I meant about the food context is, so, I don't want to use Carrie as an example because she's admitted that she does think she overdrinks. But for another person who is moderately drinking and not losing weight, so, one option might be cutting out the alcohol completely and seeing what happens, or another option might be keeping in the alcohol and adjusting the food more, and either of those situations could potentially lead to progress.  

Gin Stephens: Yeah, absolutely. But putting them together, one, two, I think would also very likely supercharge it for almost anybody. I just really feel that way. 

Melanie Avalon: That's the thing I actually don't know.  

Gin Stephens: I know. But I do want people to try it, just to see if they think. I don't know. Go ahead.  

Melanie Avalon: Well, I'm just going to say, I'm not actually-- and I talk about this a lot in What When Wine. So, people can check that out if they'd like to learn more. But I think some people might lose more if they're really intense on the food but still having alcohol, just because of some of the ways that alcohol does affect metabolism, and its thermogenic effect, and its effect on insulin, and especially like wine, potentially its effect on insulin, its effect on like a few different things. I think some people, let's say that the diet is controlled and it's a certain type of controlled diet, be it macros, Whole Foods, whatever it is, some people might lose more actually having wine with it, and I'm saying wine, but some people might not.  

Gin Stephens: I think probably a lot of it has to do with whether you're a good alcohol metabolizer or not. I've just seen my effects over time knowing how I feel. Also, having that feedback from the breathalyzer showing how it really affected how long it took me to get into ketosis versus when I didn't have it. I mean, that's huge for me. So, it would just be something I would always recommend as a tool in the toolbox for somebody.  

Melanie Avalon: I will say, if you are drinking wine, specifically drink Dry Farm Wines. 

Gin Stephens: Oh, 100%.  

Melanie Avalon: So, I went out on New Year's and we went to two different places, and the first place I went, I was able to get a wine that I had looked up the winery, like I'm pretty sure it probably wasn't as low alcohol as Dry Farm Wines or as low sugar, but I can tell now when I drink a wine at a restaurant that's not from Dry Farm Wines. I can pretty much tell if it's approaching the Dry Farm Wines spectrum. So, that one was and I was like, "Okay, I'm good." But then we went to another bar, and I got the only organic one I could find. But now, I can just so tell how high in alcohol and sugar, a lot of wines are. I wasn't hung over or anything but I had a tiny, tiny little headache and I was like, "Oh, my goodness. I got to stay with my Dry Farm Wines." So, if listeners would like to get Dry Farm Wines, they can go to dryfarmwines.com/ifpodcast and they can get a bottle for a penny there.  

I do have a question for listeners. I was brainstorming actually on New Year's Eve with one of my friends. Let me know, would you be interested and I'm contemplating developing an app that would, I know there's so many wines in the world, but you would look up wines and it would tell you if they're organic, or sustainable, or biodynamic, like that would just be so helpful for me personally, when I'm out at restaurants. Let me know if that would be something of interest for people. 

Gin Stephens: I think it would be of interest, but there really are so many different- 

Melanie Avalon: Wines. 

Gin Stephens: -wines that I don't know how you would compile that. Because some are produced in small amounts and here's what I do. I always stick to, if I'm out, I try to get something from France. [laughs] That's my metric. You know, France. If it's made in France, it's smaller kind of a thing. 

Melanie Avalon: Yeah. No, actually, so, my people, if they want to know my protocol, I look at the wine list. I don't even look at US. I don't. 

Gin Stephens: No. Not at a restaurant.  

Melanie Avalon: I look at the European ones, and then, I google the winery, and this is why I want to make this app. I google the winery and you'd be really surprised how many of them actually are implementing organic practices. The thing that Dry Farm Wines goes one step beyond is, they test the wines on top of that to make sure they are organic, and free of pesticides, and free of mold. But then they also test the alcohol and the sugar content, which when you're drinking low sugar, low alcohol wines, it's just such a massive difference. But yeah, the reason I'm thinking it's doable is the Vivino app I love and you scan bottles with it and it comes up with the bottle, and people write reviews, and it has all the information, and it has almost every wine that I scan ever so it's possible to do. Let me know listeners if that would be something of interest.  

Back to Carrie. She says, "I feel like my body is not my own even after all these years of battling the things I have not grown accustomed to it. I feel like I am battling it all the time, but I do not know why. I cannot figure out what is wrong and that is hard for me because I am a fixer." And then, what's interesting is, Carrie sent us this whole email and she didn't mention what she's eating, which is something I actually want to talk about. I emailed her to ask, what she's eating? And she said, "I eat meat, seafood, eggs, lots of veggies, salads with homemade vinaigrette, feta or parmesan, and toasted walnuts or pecans, a variety of fruits, fats, butter, avocado, olive oil, occasional cheese, processed foods like tortilla chips, occasional candy, especially, when the kids share Halloween candy, taco shells, occasional desserts, basmati rice a few times a month. I rarely eat bread and when I do its usually Ezekiel, no milk, sometimes a tiny bowl of ice cream but again once a month, a little sour cream. We do not eat out a ton because we're busy with the kids and work. I'm not perfect with my diet partly because I know it's not sustainable and if I try and fail, I will just say, nope."  

I want to circle back to this. She says, "So, I try to make the best choices as often as I can. Sometimes, I have the cupcake the kids didn't take to Boy Scouts. So, I guess my questions for you are, here we go. Number one, "Podcast listening. I love it. But should I continue working my way through it," because she has started at the beginning, "Or start with the most current and go backwards?" I'm about three years behind right now." I thought this was a really great question. I don't think anybody's ever asked us this before.  

Gin Stephens: No. I don't think so either.  

Melanie Avalon: Gin, what are your thoughts?  

Gin Stephens: I don't know. I feel like I might would start with the most current and go backwards. When we started, so many things have changed. For example, remember when we like the first year, we got that question about CBD oil and we're like, "We think that might be illegal. Don't do that." [laughs] And now, it's like there's a CBD store on every block, right? 

Melanie Avalon: I was just thinking about that. I was ordering some more Feals and I was like, "Wow, things have come so far."  

Gin Stephens: Because we're like, "I don't know. It's against the law probably. Don't use that." Times have changed so much. So, probably listening to the early ones might even be like a hilarious. [laughs] I don’t know.  

Melanie Avalon: I probably suggest doing-- so, the way I handle podcast is-- so, I listen to the new ones as they're coming out, and then, well it depends on what type of show it is. But then, I usually go back and find the episodes that look intriguing and listen to them. But yeah, you could binge listen. A lot of people tell us that. A lot of people write in and say that they're starting at the beginning. I'd be really curious to know how many people, in general, our listeners-- our new listeners, how they approach it. Like, do they go back? That's a good question.  

Gin Stephens: I would definitely listen to the new ones as they come out and also Intermittent Fasting Stories. If people are not listening to that one yet, that's one that I think-- and the Melanie Avalon Biohacking Podcast. So, I would be more likely to listen to recent of all of them versus going deep dive way back in the archives, unless, you're really looking for something to listen to, and then, that would be tell us the funniest thing you heard from Episode Two or whatever we know. Anyway, I just think we would probably cringe at some of the things we might have said early on.  

Melanie Avalon: Yeah. It's such a different format, like the Biohacking Podcast would definitely be one. It doesn't-- 

Gin Stephens: It's not sequential.  

Melanie Avalon: Yeah. It's like episodic. So, any-- 

Gin Stephens: Same with IF Stories. 

Melanie Avalon: You would basically just go on the topics that you want to listen to. This one it's a lot of the same topic but yeah, it's a good question. So, number two is, "Two and a half months with zero results a thing. All the questions I've heard, no one else asked about going this long with no weight loss. I keep listening, thinking someday someone will ask all the same questions and the clouds will part, the angels will sing, and I'll know what to do." So, two and a half months with zero results.  

Gin Stephens: All right. So, here is a place where Intermittent Fasting Stories can come to the rescue. There are lots of episodes. Lots and lots of episodes out there, but two that really stand out for me as episodes for going a long time with no weight loss. One of the most recent ones that I did has still been a while. Episode 125, Roxi. If you just go to like Google and type in Intermittent Fasting Stories, Roxi, it'll help you find Roxi's episode. But Roxi started intermittent fasting, she was feeling great, she was rolling along, losing no weight at all. Then, she went back to her doctor and had a re-check. She had been diagnosed with fatty liver disease before she started fasting. Doing intermittent fasting for all these months, went back to the doctor, her fatty liver disease was completely reversed, but she hadn't lost any weight. So, it didn't show up on the scale, but clearly her body was busy doing something, which is pretty exciting.  

Now, there's another episode to look at. Oh, and by the way, I just want to say imagine, if Roxi had quit, because she thought it wasn't working for her. "Oh, this isn't working. I'm going to quit." She was clearing out a fatty liver. So, eventually she did go on to start losing pounds on the scale and she's gotten smaller or sizes changed, but that episode just really always inspires me and her story.  

Melanie Avalon: How much did she weigh?  

Gin Stephens: I don't remember the weight exactly but she was overweight.  

Melanie Avalon: Okay. I'm just wondering if she was obese.  

Gin Stephens: I'm not sure exactly whether she was in the obese category or not but she definitely had the fatty liver. So, having a fatty liver, it's not something you want. So, here's another story that is, it's Episode 50, and it's Renee and Joel. They are mother-son. Renee is the mother, Joel is the son, and when they started intermittent fasting, they both started it at the same time. He did not lose a single pound for the first eight months of doing IF. But in the ninth month, the weight just started to fall right off, he didn't change a thing, just boom. The weight started to go and he lost the 20 pounds that he wanted to lose after eight months of losing nothing. So, listen to those two stories.  

The thing is that something is happening in the body. You know what was going on in Joel's body? I don't know. Maybe, his insulin was coming down. Listening to this, Why We Get Sick? If he had hyperinsulinemia, insulin is such a storage hormone. It may be all that was happening for eight months is his body's fasted insulin level, his level of circulating insulin that goes around all the time was going down, down, down, down, down. Then, when it got to a certain point, bam he was able to lose the weight he wanted to lose. That 20 pounds dropped off so quickly after nothing.  

Melanie Avalon: That's like Gary Taubes' theory about the insulin threshold. 

Gin Stephens: Yeah, absolutely. I totally believe that could be a factor. For Roxi, fatty liver, fatty liver, fatty liver, bam. All of a sudden, she started losing the weight. So, something good is happening in the body when you're doing intermittent fasting and you can't always see it. So, there was that.  

Melanie Avalon: She didn't say what window she's doing, does she?  

Gin Stephens: Well, she said that minimum of 16 and sometimes 20 to 21. Here's what I've noticed from years in the Intermittent Fasting Community. When people would say, "I always do at least whatever, and sometimes, I did this." If they start tracking their fasts on an app, they realize that they might skew a lot more to the 16 and less to the 20 than they thought. That's just something to keep in mind. If you're fast or usually 16, 16, 16, 16, every now and then you do a 20 or 21, you're likely not getting into that peak fat burning that starts to ramp up around our 18. Just pushing it to 19 consistently instead of 16 consistently could make a difference. Just something to consider. Try an app and see what you're doing. Because for me, I needed a consistent 19 to really get that fat burning in and to lose the weight that I wanted to lose. 

Melanie Avalon: Yeah, I guess for me, so, I think it's very telling for Carrie, well, first of all, Carrie, I really, really identify with you and I can see why you feel like our stories are really similar because for listeners, who are not familiar, a lot of my health issues started with GI distress, and SIBO, and antibiotics, and just feeling like my gut got off after this catalyzing incident, and just being a rocky road ever since then. So, I completely identify and I know what this is like for so many people. This isn't even about the weight loss. This is about the health issues that she was experiencing. You just you know something's off, and you just want to find answers, and you try all the things like Carrie has done. So, parasites, and heavy metals, and herbs, and cleanses, and going after this liver virus, and antibiotics, and just trying all these different things. I know that it's very scary and it can feel very disheartening. So, I'm completely there with you.  

For me what happened, I hit burnout with all of it. I hit a point where I was like, "I don't care." Like, I'm not testing anymore, I'm not going to try to fix whatever the specific thing is through a specific supplement or through a specific thing, and I don't know that the ideal mindset to be in either, but the takeaway that I learned from all of that and where I am now, it's really easy to get caught up in the minutiae and try to go after these specific things that you think might be in you or that might be off. When I think if you just step back and breathe, and take a more holistic approach that's foundationally based on diet and food, I think there's massive, massive potential there. You can be doing all these things, but if you're taking in food that is not supporting your gut microbiome and it's contributing to these issues, that's difficult to address. And then, on top of that, there's so much potential that can be gained when you are eating a diet that's really, really supporting your body and helping address that. All that said, so, as far as like, where to focus and like, "Where the answer is?" There might be things that you really, really do need to focus on and address. 

So, for me, the heavy metals were really bad for me. My blood levels of mercury were over 30 which is just shocking. So, that was something I did need to address. For me, I do have to keep monitoring my anemia, for example. That's not something I can just be like, "Oh, I'll just eat food and be okay." No, I actually, I use InsideTracker and I stay on top of my ferritin and my iron because that mine has a tendency to drop. So, there are things that are important to focus on and keep in mind, but I think maybe getting out of the detox mindset and entering a healing diet food mindset can't be understated. I also empathize as well. Carrie has this mindset of the perfectionism mindset. So, she's worried that, I'm going to say it again. She says, "I'm not perfect with my diet partly because I know it's not sustainable and if I try and fail, I will just say, no." So, that's really hard to navigate because I as well, I'm a perfectionist and an all or none person. And I know it's very easy, it's a slippery slope, where some people respond to not being perfect with just throwing it all out the window, which is a really interesting mindset justification that we make that doesn't have to be. So, you can still strive for perfect and then, if you're not perfect, that's okay. But if you're not perfect, it doesn't mean that you throw everything out the window and just lapse into rebelling against perfectionism. You can still strive for perfect but things can be good.  

It's interesting, I just finished Cynthia Thurlow's new book, and she talks about this, and she recommends a, I think, she calls it a good, better, best mindset. So, she says, "Every single day is either a best day." So, that would be like the equivalent of "perfect." So, you ate all the foods you want to eat, you did the fasting the way you want to do it, etc., Then, there's the better day. So, that's where like, you're almost there but some things were like a little bit off, and then, there's the good days, which maybe more things are off, but either way, you're always making progress. So, I would really suggest that mindset, Carrie, applying that to your diet. So, striving for those best days rather than saying, "I'm not even going to try." Because I know you don't want to track and you don't want to be perfect, but it might be that you're not going to be able to make the progress that you want without addressing the actual food choices of your eating window. Intermittent fasting can be amazing. But for some people, it's not going to be enough to actually make the change. We can tweak the window, we can fast more, but at some point, some people, you've just got to look at what you're eating. 

Gin Stephens: And you know to me, that's funny to hear you say that, because what she described is what she eats sounds pretty great. It sounds very cleanish. It's very much like the way I eat. She's eating meat, seafood, eggs, lots of veggies, salad with homemade dressing. It sounded like a pretty, pretty great diet to me.  

Melanie Avalon: Well, that's the thing. So, I think what it sounds like to me, just looking at it briefly, skimming through the foods like, "Oh, this is a good diet." So, I think maybe she's found a safety within that, when you're saying people, they think they're fasting a certain amount but they're not quite. I think it might be the situation with the food. So, she feels like it's healthy, but the cheese, the fat, the processed food, if her insulin levels are high enough and her carb intake is enough such that she is at a more of a storing mode than having the fats, the cheese, the things like that, they might be every time she's eating, adding in enough excess nutrition that she's not going to ever lose weight unless she gets a little bit more strict.  

Gin Stephens: That's what my tweaks recommended would address that exact thing would be try to delay the alcohol for a month. See what happens if you just avoid the alcohol and just push that window length a little bit. That would give you the same benefit in lowering your insulin because you're fasting a little bit more. It seemed like a pretty good a balanced kind of a way because otherwise you're just like dieting hardcore. So many of us don't want to diet hardcore.  

Melanie Avalon: Okay, that's the mindset I'm trying to dismantle right now. Because she's eating what she's eating but she doesn't want to diet hardcore.  

Gin Stephens: Right. I don't think she needs to change what she's eating.  

Melanie Avalon: She could substantially change what she's eating without it being dieting hardcore.  

Gin Stephens: See, I don't think she needs to substantially change what she's eating. I guess, that's where we're having that disconnect. She has occasional candy. I eat tortilla chips. I eat occasional candy. She seems like she's eating a very good diet to me. I don't know. To change it up would seem hardcore to me.  

Melanie Avalon: I think for some people if they're eating fats and carbs in their meals, especially, cheese in there, butter in there, nuts in there, cheese, nuts, things like that can easily be very weight promoting. It might be that in order to lose the weight, it doesn't have to be crazy. But eating just Whole Foods, so no longer adding additional fats like still eating your normal meats but not adding the fats, not adding nuts, not adding cheese, you might see massive, massive changes. It doesn't have to be like counting calories, and it doesn't have to be super intense, but just making some tweaks, and that's what I'm trying to dismantle like, there's a lot of change she can make to her diet. That's not going to be crazy dieting, it doesn't have to seem like really restrictive, but it might make super, huge changes pretty quickly. It could also be a macros approach. So, if you do want to keep in the fats, maybe, you're trying low carb. There're different ways that you could try it. But you could tweak it within a paradigm that is not super restrictive, not super crazy, but might be addressing the things that might be making it impossible. 

Today's episode is sponsored by Prep Dish. I want you to think through your day. What are the hectic daily moments you dread? For many of us, it's 5 PM when you realize the dinner hour has somehow snuck up on you again and you have no plan. Naturally, this is also the time young kiddos start losing it. Trying to throw together a healthy meal amidst that chaos is just plain hard. Even though, my kids are grown, I remember those days well. Often, I would just hit the drive thru again, Prep Dish is the best way for busy people to get healthy meals on the table without the stress. Subscribers receive an email every week with an organized grocery list and instructions for prepping meals ahead of time. This means dinnertime is super quick and easy every day. The best part, Prep Dish has weekly superfast menus. This means in addition to gluten free, paleo, and low carb, or keto menus, subscribers now receive a new superfast menu each and every week. These menus require only an hour to prep the week's food and we're not talking boring pasta or plain chicken. Super-fast menus include items like shrimp tostadas, slow cooker sausage and kale soup, and smothered mushroom chicken with mashed potatoes. The founder, Allison is offering listeners a free two-week trial to try it out. I mean, what's better than free? Nothing. Check out prepdish.com/ifpodcast for this amazing deal. Again, that's prepdish.com/ifpodcast for your first two weeks free. And now, back to the show.  

Gin Stephens: I think that probably a good majority of the people out there don't want to tweak by eating less fat, or less carbs, or go low fat, or go low carb, I think we just want to eat real food. I don't want to have a potato with no butter or butter with no potato. I want to have a potato with butter. The way that I and a lot of people are able to have the potato with the butter is by focusing on maybe a 19-hour daily fast instead of 16, and by being careful with how much alcohol and things like that. I know that some people are really excited to try leaving out certain macros. But I think a lot of people really just don't want to do that. I don't know. Something to think about. She could certainly do whichever of those seems appealing to her. We've given her a lot of tools to pick from, I think. 

Melanie Avalon: I don't want to make blanket statements because I don't know what the majority of people want.  

Gin Stephens: Can I be honest with something? Somebody in my community listened to last week's episode, where we talked a lot about cheese and nuts, and was a little salty about it. There was some feedback of feeling like, we are telling people what to eat and what not to eat. She said, "We." She wasn't talking about you, it's about me and you. A very interesting discussion ensued in the community. So, that's why I wanted to bring that up. A lot of people really don't want to count macros. They don't want to do the low fat, they don't want to do the low carb, they just want to eat food. 

Melanie Avalon: What's interesting is, I had some feedback as well, but it was the complete opposite. This is why I think like, I'm just about telling people options and you find what works for you. People just find what works for you but we had one listener write in and she was saying that, I think she was talking about the protein and the fruit. We made the suggestion about maybe trying to bring in other types of carbs because, maybe you could have them and then she reported back to me, she was like, "Nope, you know that didn't work at all." I think it's all very individual and I think we see the world through the way we approach it. So, for me, I do better with macros, and I do better being more strict on what I'm eating. And some people are like that as well. I think you see through the lens of not like that.  

My foundational thing, though is that, I think people are so nervous about falling into restrictive diety mindsets and they don't want to ever count calories, they don't want to ever track anything that sometimes it can be-- we like to ignore the fact that certain foods are very likely weight promoting, and make it harder to lose weight if they're in there, and that might just be-- I don't like to ever saying something is a reality, but approaching a reality. That's why I'm trying to suggest like the good, better, best approach, and I just thought it was really interesting that she didn't even mention what she was eating. The email I cut it down from, it was probably three times as long. But there wasn't any mention of the foods, which said to me that there wasn't a focus at all on the food. She probably feels like the food is a healthy approach, and so, there's not much tweak there, and I just think there's so much progress that can happen if things are tweaked. I am never trying to enforce or impose my beliefs on anybody. This is going to sound callous, but I really could care less when people do. Like, "Do what you want, I don't care." I just want to tell people, what has worked for me and it may or may not work for you. But if things aren't resonating with people, I'm sorry. But it doesn't really bother me-- that does not bother me.  

Gin Stephens: Yeah. The feedback was that, we were demonizing cheese and nuts. I really don't think that we came across as demonizing cheese and nuts. We were just saying, they're easy to overeat. But that's not us saying those are off the menu. I eat cheese, I eat nuts, but I am mindful that I can easily over eat cheese. But I'm not overeating cheese right now.  

Melanie Avalon: I know the way I've talked about cheese and nuts. I don't think I've demonized them. I have not intended to. I do think pretty objectively they are foods that can be very weight promoting. So, it sounds like a defensive reaction because people want to keep it in. 

Gin Stephens: Well, I definitely want to keep cheese and nuts in my diet and I want to eat them. I just need to be mindful. The same with like tortilla chips. She eats tortilla chips, I eat tortilla chips. But I mindfully eat them and I choose really high-quality ones. 

Melanie Avalon: So, a simple concept of cheese is easily weight promoting. Again, I don't like to say anything black or white, I'm fairly certain that that's a pretty accurate statement. So, what you do with that is up to you. So, you know you can keep it in moderation, find the way that it works for you, it doesn't change the fact that it might be weight promoting if had in excess, which often happens. 

Gin Stephens: Right. I think that's often very key said in excess and it's just hard to know. You're probably not going to have broccoli in excess, but it is a lot more likely to have cheese in excess. So, I just wanted to point that out. 

Melanie Avalon: Literally, listeners, do what you want. [laughs] Do what you want. I just think it's funny because I think people, I know we're on like tangents, but I think sometimes people think that I have an agenda or I'm trying to convince people of anything. I really not. Like, do what you want. I'm just going to tell you what worked for me, and what I've learned, and what I think might help. Yes, I have no agenda. 

Gin Stephens: I do have an agenda. Do you know what it is? I want people to enjoy what they're eating without stressing about it. That is it. That is what I know you do, too. But that is what Clean(ish) is all about. it is figuring out what things you want to include. There's the 'ish.' I know that a tortilla chip fried in an oil that is one of those inflammatory oils is not great for my body. But I'm still going to include them in small amounts because I enjoy them. I'm not going to veer so far to perfection that I'm not enjoying the way I love and you're not either, Melanie. You very much enjoy the way you live. But it's a matter of finding your own balance of what foods you enjoy that make you feel good. My friend, Laurie Lewis, she says it beautifully. She says, "You want to love the foods that love you back. You want to pick the foods that make you feel great and are delicious, and you're balanced in a way that your weight ends up being at a stable level, where you feel comfortable." Sometimes, you do have to make some, like that period of time where I didn't drink alcohol and I didn't have those tortilla chips or other ultra-processed foods for 10 weeks.  

This was in the spring of 2015. So, would you say that I was dieting? All right, maybe so. I was not having certain things because my goal was to lose weight more quickly. I still ate a lot of good things, I had plenty of fats and carbs together, but I just didn't have alcohol or ultra-processed foods. Potato with butter, yes. Tortilla chips, no. I lost weight the most quickly I ever lost two pounds a week and then kept it all off. That was that kind of a thing. But it was delicious and I enjoyed it. So, my agenda and I think Melanie's, too, is for you to find a way to get the results you're looking for while loving the journey.  

Melanie Avalon: Yes, exactly. This is what you just said but it might be for certain people with certain goals. But you do have to do some sort of tweak. 

Gin Stephens: There's the delay, delay, delay the extra cheese that whenever you eat it, you don't lose weight. Whatever it is. For me, it was delaying the alcohol. So, someone might say, "Gin is anti-alcohol." No, I'm not. I wish I could enjoy it more. My body tells me, "Nope, that's too much for you. I have to have a little bit." But I'm certainly not anti. I just know that for me, that is a big, big factor. So, I'm always going to suggest that, that might be something to look at.  

Melanie Avalon: I'll just read really quickly her next question. She says, "I'm sure there will be more supplements introduced to me through future episodes as I catch up. Based on my situation, do you have any you really recommend for me? Obviously, you're not doctors. I get that. Based on anecdotal evidence, are there any that you recommend?" Again, so, this was from her original email, which did not mention anything about food? Again, it was this five I got of looking for the answer in a supplement rather than the foundation of diet.  

Gin Stephens: Yeah. I don't think there're any supplements out there that you can take that. It is like the reason you're not losing weight that I can just blanket say is everybody's reason. Maybe, let's say, your thyroid is all messed up. A thyroid medication or thyroid support is obviously going to be transformational for your body. But that doesn't mean everybody needs to go take thyroid medicine or a thyroid supplement. So, there's nothing we can blanket say, "Here's what you need to help the weight loss happen." 

Melanie Avalon: I will say, one I do in general, that one that I do take every day though. But this is not to lose weight but to help with insulin sensitivity and stuff like that is I do take berberine every day. But there's not some sort of magical supplement that is going to make you lose weight. And then, her last thing she says, "Tips, advice, or anything I may not have thought of. I wish you both a very Merry Christmas and Happy New Year. Much love," Carrie. So, keep us updated with how your journey goes. I will say, I really, really like her mindset. Despite all of this, she said multiple times, she said things like how she like, I'm paraphrasing, but something about how she doesn't know why she's going through this. But she knows there's a reason, and she's not giving up hope, and we're right there with you. Like, your mindset is really, really wonderful, and I know you'll find answers, and I do want you to know that I've definitely been there with everything just feeling like it fell off the wagon health wise, and not knowing what to do. So, I applaud you for really taking agency and trying to find answers, because a lot of people don't. So, yeah, you'll find it. 

Gin Stephens: I did have one more thing I wanted to pop in there, and it was me circling back to the fact that she did the ZOE program, and I really think if you've got all that data from ZOE, that could really help you figure out your diet without trying to be perfect about it. Because again, ZOE doesn't expect you to be perfect, you're not trying to get hundred on your score. So, if you put the meat in and it takes you down to a 70, you might be like, "Oh, this is terrible." But actually, it's not. That 70 is not a terrible score. So, you may want to listen to Episode 170 of Intermittent Fasting Stories. I interviewed Kristi Osborn. She's also really active in the Delay, Don't Deny Community. For anyone who's looking for that, you can go to ginstephens.com/community. Kristi's story is pretty amazing. She was also having a really hard time losing weight, loved intermittent fasting, and how she felt.  

But once she really embraced ZOE, and she doesn't like tracking either. She's not like loving the tracking part or trying to be perfect with ZOE. But it absolutely changed everything. So, I just wanted to pop that in there. She finally lost a lot of weight. She's actually in the community and she is part of the-- we have a little ZOE space in the Delay, Don’t Deny Community where people can come and talk about their experiences. She really does a great job guiding people how to make the most of it without letting it make you crazy. Because if you look at it through the lens of perfectionism, and like, it's a diet that's telling you what you have to eat and what you can't eat, that would be very like that diet brain kind of thing going on. Instead of like, "Oh look, my avocado toast score is higher with more avocado than adding an extra egg or something." It just might surprise you. You had to tweak those food combinations to get a higher score for you.  

Melanie Avalon: Yeah, and actually to that point, the mindset that's worked well for me. So, if you are addressing the types of foods you are eating, focusing on unlimited of certain types of foods rather than like, "Oh, I can't have this, I can't have that." Being like, "Oh, I can have unlimited of all of these foods and then--"  

Gin Stephens: [laughs] That's just so the opposite of the way I could be. If I get told myself, "I can have unlimited of anything, I just don't do well with that approach."  

Melanie Avalon: Within the certain macronutrient that I'm following.  

Gin Stephens: I know. But I'm just saying that, it is just so interesting how our minds like the way that we-- I'm trying to explain how to put it. I don't know. I could overeat something if I told myself that's unlimited. Okay, I'm sorry.  

Melanie Avalon: Even if it was within an intense macro nutrient. So, unlimited within a low-carb world or unlimited within a low-fat world.  

Gin Stephens: I'm pretty sure I did overeat when I was unlimited in the low-carb world because I never lost any weight.  

Melanie Avalon: I guess, I do high protein, low fat. It's so funny. IF turned so many people onto this. I'm really trying to think of this should be my next book.  

Gin Stephens: High protein, low fat, is that what you said?  

Melanie Avalon: Yeah. But lean meats and fruits specifically for me. This is what I've been doing for years. It is like unlimited lean protein, unlimited cucumbers, unlimited fruit, all I want. It's just a setup because of the metabolism of those macronutrients, especially, within a fasted window. It's very unlikely you'll gain weight and if anything, you might lose weight.  

Gin Stephens: I just know that the one reason I never did Weight Watchers is, they have the zero-point foods. I'm pretty sure I would be overeating zero-point foods, I'd be gaming that system and probably gaining weight. [laughs] I don't know. I just know my own mindset. I do much better focusing on satiety, listening to those hunger cues instead of telling myself this one's on limited. I don't know.  

Melanie Avalon: Yeah. Which I guess the foods I focus on, like, protein is the highest for satiety. So, it's like a double whammy. But yeah. People view the world all different ways.  

Gin Stephens: It is. Just like, we were naming foods whether we liked them or not. We were the opposite on all of them.  

Melanie Avalon: Oh, Gin and I, yeah, [laughs] I can tell you, every food Gin won't like or will like based on if I like it or not.  

Gin Stephens: Probably for a lot of them. Does Gin like cucumbers?  

Melanie Avalon: You like cucumbers?  

Gin Stephens: No.  

Melanie Avalon: Okay. Do you like lima beans?  

Gin Stephens: I love lima beans.  

Melanie Avalon: I can't stand lima beans.  

Gin Stephens: If you told me, I could just have unlimited lima beans, I would just eat lima beans till I exploded.  

Melanie Avalon: If there's one bean I can't, like, lima beans. Or, what about hazelnuts?  

Gin Stephens: I like hazelnuts. They're so good.  

Melanie Avalon: I don't like hazelnuts or oranges.  

Gin Stephens: I love oranges.  

Melanie Avalon: I love most foods. So, that's the thing. There are very few foods I don't like.  

Gin Stephens: There's really very few foods I don't like. 

Melanie Avalon: What do you not like?  

Gin Stephens: I don't like cucumbers. Well, when I start listing them, I don't like anything that you're going to have on sushi. Let me put it that way. When I was in Tampa-- 

Melanie Avalon: Ginger?  

Gin Stephens: Oh, I like ginger. Okay. I like ginger. I like ginger, I like wasabi, I like the sauces. But everything they roll up, I mean, I like rice. But anything else practically that they're going to roll up in there, I don't like the cucumber and they all have cucumber. I don't like fish, they all have fish.  

Melanie Avalon: I love fish.  

Gin Stephens: [sighs] Anyway, it's like the one restaurant I do not want to go to you with is a sushi restaurant because I have a hard time finding anything I want.  

Melanie Avalon: It's so funny. What is the one food you dislike the most? Oh, I don't like oysters.  

Gin Stephens: I don't like any kind of fish and I don't like oysters.  

Melanie Avalon: But mine is probably oranges.  

Gin Stephens: I love oranges. You do not like oranges that much?  

Melanie Avalon: They give me a raging headache.  

Gin Stephens: Oh, no, I love them. If I'm ever sick, I start to crave orange juice and it always makes me feel better. I need the pulpy kind. Pulpy orange juice, love it.  

Melanie Avalon: Oranges and grapefruits.  

Gin Stephens: I like grapefruits.  

Melanie Avalon: I think I have a reaction to some compound--  

Gin Stephens: To citrus?  

Melanie Avalon: I love lime and lemon. There's something in orange that just-- 

Gin Stephens: That's so interesting.  

Melanie Avalon: You're not a huge watermelon fan, right?  

Gin Stephens: Oh, I hate it. It's gross. I don't like any kind of melon. See, I think cucumbers are in that Melanie kind of. I don't like cucumber or any kind of melon. I don't eat a fruit salad that has melon in it because it has infected the rest of the fruit with its grossness. [laughs] 

Melanie Avalon: Oh, the best, because I'm a fruit lover and out of the fruits, all of the melons.  

Gin Stephens: I like pineapple, I like oranges, I like strawberries, I like any kind of berry. 

Melanie Avalon: I like berries.  

Gin Stephens: I'll eat an apple if it's in a pie.  

Melanie Avalon: It's so funny.  

Gin Stephens: It really is. It is so funny.  

Melanie Avalon: All right. Well, this was a fun time. So, for listeners, if you'd like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go at ifpodcast.com and you can submit questions there. The show notes will be at ifpodcast.com/episode248. Definitely follow us on Instagram because we just got actually a new fabulous woman who is going to be helping us with our Instagram. Shoutout to Shannon. So, we're going to start posting and interacting there more. Oh, and in case you're wondering, it's not like just Shannon. I am very much-- Gin and I are both, we see it and I'm there. When I go on to my Instagram on my phone, I'm there. Don’t want to think they were like outsourcing it. So, definitely follow us on Instagram @ifpodcast, I am @melanieavalon on Instagram. Gin is @ginstephens, and I think that is all the things. Anything from you, Gin, before we go? 

Gin Stephens: No, I think that's it.  

Melanie Avalon: All right. Well, this was absolutely wonderful and I will talk to you next week.  

Gin Stephens: All right. Bye.  

Melanie Avalon: Bye.  

Melanie Avalon: Thank you so much for listening to the Intermittent Fasting Podcast. Please remember that everything discussed on the show is not medical advice. We're not doctors. You can also check out our other podcasts, Intermittent Fasting Stories, and the Melanie Avalon Biohacking Podcast. The music was composed by Leland Cox. See you next week. 

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Gin: GinStephens.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Dec 26

Episode 245: Modifying Eating Windows, Plant Based, Processed Food, Chronic Fatigue, Soy & Tofu, Sugar Alternatives, Corn, Potatoes, And More!

Intermittent Fasting

Welcome to Episode 245 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Gin Stephens, author of Delay, Don't Deny: Living An Intermittent Fasting Lifestyle

Today's episode of The Intermittent Fasting Podcast is brought to you by:

BUTCHERBOX: Grass-Fed Beef, Organic Chicken, Heritage Pork, Wild-Caught Seafood: Nutrient-Rich, Raised Sustainably The Way Nature Intended, And Shipped Straight To Your Door! For A Limited Time Go To butcherbox.com/ifpodcast And Get The Ultimate New Year’s Bundle, More Than 7 Pounds Of Meat Added To Your First Box For FREE!!

 JOOVV: Like intermittent fasting, red light therapy can benefit the body on so many levels! It literally works on the mitochondrial level to help your cells generate more energy! Red light can help you burn fat (including targeted fat burning and stubborn fat!), contour your body, reduce fine lines and wrinkles, produce collagen for epic skin, support muscle recovery, reduce joint pain and inflammation, combat fatigue, help you sleep better, improve mood, and so much more!! These devices are literally LIFE CHANGING!! For A Limited Time Go To Joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

BiOptimizers: A Company Whose Mission Is To Fix Your Digestion! Support Your Gut Health With A Patented, Proteolytic, Anti-Viral, Superstar Probiotic, P3OM! Go To p3om.com/ifpodcast And Use The Coupon Code IFPODCAST10 To Save 10% Off Any Order!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

BUTCHERBOX: For A Limited Time Go To butcherbox.com/ifpodcast And Get the Ultimate New Year’s Bundle, more than 7 pounds of meat added to your first box for FREE!!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At MelanieAvalon.com/beautycounter, And Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: melanieavalon.com/beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

Stay Up To Date With All The News About Melanie's New Serrapeptase Supplement At melanieavalon.com/serrapeptase Or Head Straight Over To avalonx.us To Place Your Order Now!

JOOVV: For A Limited Time Go To Joovv.com/ifpodcast And Use The Code IFPODCAST For An Exclusive Discount!

Listener Q&A: Melanie - episoode #1 and eating earlier

Listener Q&A: Angela - Processed vs. Plant Based

The Melanie Avalon Biohacking Podcast Episode #61 - Dr. Cate Shanahan

The Chef's Garden Book

bioptimizers: Go To p3om.com/ifpodcast And Use The Coupon Code IFPODCAST10 To Save 10% Off Any Order!

Listener Q&A: Julie - How did i get here?

TRANSCRIPT

Melanie Avalon: Welcome to Episode 245 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Gin Stephens, author of Fast. Feast. Repeat.: The Comprehensive Guide to Delay, Don't Deny Intermittent Fasting. For more on us, check out ifpodcast.com, melanieavalon.com, and ginstephens.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment. So, pour yourself a cup of black coffee, a mug of tea, or even a glass of wine, if it's that time, and get ready for The Intermittent Fasting Podcast. 

Hi, friends. I'm about to tell you how you can get more than seven pounds of high-quality responsibly farmed meat all for free. Yes, for free. So, the holidays are upon us and I don't know about you, but when I think about holidays, I often think food, and then the second thing I often think is, "Hmm, I wonder what will be the quality of all of the meat and seafood at all of the family gatherings." It can definitely seem intimidating and expensive to get high quality meat that you can trust. Thankfully, there is an easy solution. It's a company I've been a fan of for years and that is ButcherBox. They are an incredible company that takes out the middleman of the grocery store to directly connect customers to farmers. They vet these farmers, they find the farmers that truly support the health of the animals, the environment, and ultimately, your health so that you can finally get meat of the highest standards, 100% grass-fed, grass-finished beef, free range organic chicken, wild caught seafood, and more. And trust me, the seafood industry is sketchy. ButcherBox goes to great lengths for transparency and sustainability so you can truly feel good about what you're eating. I read Dr. Robert Lustig's book, Metabolical and was blown away by the shocking statistics of fraud in the seafood industry. But back to meat. ButcherBox's meat is delicious. Each box contains eight to 14 pounds of meat depending on your box type. It's packed fresh and shipped frozen for your convenience. You can choose a curated box or customize it to get exactly what you want, and it's shipped straight to your door, and it tastes delicious.  

The ButcherBox steaks are honestly some of the best steaks I've ever had in my entire life. My dad is a huge spaghetti fan and he remarked that the ground beef was the best ground beef he had ever had. My brother reported back about the porkchops and the bacon, basically, this stuff is delicious. And for limited time, ButcherBox is offering new members an amazing deal for the new year. Just sign up at butcherbox.com/ifpodcast, and you'll receive the ultimate New Year's bundle in your first box. This deal includes grass-fed, grass-finished ground beef, organic free-range chicken thighs, and heritage breed pork butt. That's more than seven pounds of meat added to your first box all for free. So, get this New Year's bundle before it's gone by going to butcherbox.com/ifpodcast. That's butcherbox.com/ifpodcast. And we'll put all this information in the show notes. 

And one more thing before we jump in. Are you fasting clean inside and out? Did you know that one of our largest exposures to toxic compounds, including endocrine disrupters, which mess with our hormones, obesogens which literally cause our body to store and gain weight, as well as carcinogens linked to cancer is actually through our skincare? Europe has banned thousands of these compounds for being toxic, and the US has only banned around 10. It's honestly shocking. When you're putting on your conventional skincare makeup, you're likely putting toxic compounds directly into your body. These compounds can make you feel bad, can make it really hard to lose weight, can affect your hormones, your mood, your health. And ladies, if you're thinking of having kids, when you have a child, these compounds actually go directly through the placenta into the newborn. That means your skincare makeup that you're putting on today actually affects the health of future generations.  

Did you know that conventional lipstick for example often tests high for lead, and the half-life of lead can be up to 30 years in your bones? That means when you put on your lipstick, 30 years later, half of that lead might still be in your body. Thankfully, there's an easy, easy solution to this. There's a company called Beautycounter and they were founded on a mission to change this. Every single ingredient and their products is extensively tested to be safe for your skin. You can actually feel good about what you put on. And on top of that, their products actually work. That's because they're not “all natural.” They actually combine the best of both worlds, both synthetic and natural ingredients, to create products that actually support the health of your skin and make your skin look amazing. They have skincare lines for all your skin types, deodorant, shampoo and conditioner that I love, anti-aging and brightening peels and vitamin C serums, and incredible makeup. If you see my makeup on Instagram, that's all Beautycounter. You can shop with us at melanieavalon.com/beautycounter 

And if you're thinking of making safe skincare a part of your future, like we have, we definitely suggest becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders and a welcome gift that is worth way more than the price of the yearlong membership, totally completely worth it. Also, definitely join my clean beauty email list at melanieavalon.com/cleanbeauty, I give away a lot of free things on that list and join me on my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. I do a weekly giveaway every single week for Beautycounter, people share their experience and product reviews, and so much more. And again, the link to shop with us is melanieavalon.com/beautycounter. All right now enjoy the show.  

Melanie Avalon: Hi, everybody and welcome. This is Episode number 245 of the Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here with, Gin Stephens.  

Gin Stephens: Hi, everybody.  

Melanie Avalon: How are you today, Gin?  

Gin Stephens: I am fabulous because I am at the beach cottage with Will and we're having a great time.  

Melanie Avalon: That's lovely.  

Gin Stephens: It was a spur of the moment kind of a trip. I was going to come this weekend with college friends, but then we had the ACC championship. So, we did that last weekend. So, they're like, "We can't get away again." I'm like, "That's fine. I'll go by myself." Will didn't have anything to do. I'm like, "Come with me." So, yeah, he's doing a lot of painting. Now, he's sitting on the beach with his guitar. [laughs]  

Melanie Avalon: He's so creative.  

Gin Stephens: He really is. He is so creative. He's 22 and completely right brained and is happiest when he's creating something. He likes to create music, he writes music, and now, he likes to paint. So, I love that.  

Melanie Avalon: Yeah. Well, I had a fun event on Friday.  

Gin Stephens: Oh, what was that?  

Melanie Avalon: I had dinner with one of my podcast guests.  

Gin Stephens: Oh, that's fun. I love it.  

Melanie Avalon: I know. It was very exciting. It's weird. I was thinking about it. Most of my really good friends now are all people I've met on my Biohacking Podcast. Isn't that weird? It's so crazy.  

Gin Stephens: You know, it sounds weird except that a lot of my really good friends are people that I met through my Intermittent Fasting Groups and like their real good friends. I mean, obviously, my college friends are people I've known a long time but a lot of my really close friends have been on my podcast. All right, I didn't meet them till after they were on my podcast like face-to-face.  

Melanie Avalon: The people I talk to pretty much every day are people I met in the podcast and then just started talking to after and really got to know really well. So, the person I went with though, I'm not super close or anything, but it was Dr. Eric Zielinski. So, he wrote The Healing Power of Essential Oils. I think that's the title of his first book. I didn't even realize we have the same agent, all of us.  

Gin Stephens: Oh, that's great. So many people do.  

Melanie Avalon: I know, I know. Same literary agent. Yeah, it was so fun. So, it was me, and him, and his wife, and their new baby, and my sister, and it was just a really fun time. It was really fun because yeah, like I just said it was only the second person I've met in real life from the show. Because he actually lives here in Atlanta.  

Gin Stephens: I've met people in real life that you haven't met in real life that I met through you.  

Melanie Avalon: Oh, yeah. Are true. So, yeah, it was really fun.  

Gin Stephens: Like, I can think of three. Three people that I've met in real life that I know through you only, but I've met them in real life and you have not. [laughs] And I'm not counting Cynthia Thurlow, because I actually met her first.  

Melanie Avalon: Oh, wow.  

Gin Stephens: Yeah, she and I met first. We were on a radio program together. We didn't know anything about the other person and we both talked afterwards about here, we're like, "What is she going to say? Is it going to be the opposite of what I say?" But we found we were very in sync.  

Melanie Avalon: I was actually reading her book last night, her new book. 

Gin Stephens: Her book comes out March.  

Melanie Avalon: Oh, in March. Okay. So, her book is about intermittent fasting and I'm not saying this to sound like a 'no' at all, but when I read a book about intermittent fasting, it's just so overwhelmingly familiar, like all of the information.  

Gin Stephens: You're like, "Yep, yep, yep."  

Melanie Avalon: It's hard for me to think what would this be like to read this. 

Gin Stephens: For the first time?  

Melanie Avalon: Mm-hmm.  

Gin Stephens: I know what you mean. I 100% get it. But yeah, I met her first and then, you met her later. But the other three, can you think of all three of them?  

Melanie Avalon: Shawn Wells.  

Gin Stephens: Yes.  

Melanie Avalon: Anna Cabeca.  

Gin Stephens: Oh, I forgot about her. Okay, four. [laughs] Yes, Anna Cabeca, four, because I forgot that I met her through you. But I did. Yes.  

Melanie Avalon: Wade Lightheart.  

Gin Stephens: Yes.  

Melanie Avalon: And, okay, so, there's one more.  

Gin Stephens: Yep. Somebody, he is been on our podcast. Oh, and there's another one, too. There's five. Both of the others have been--  

Melanie Avalon: Oh, Todd White.  

Gin Stephens: Yes. And of course, we can't forget the main one. The reason I was at the conference.  

Melanie Avalon: JJ Virgin.  

Gin Stephens: Yeah.  

Melanie Avalon: Oh, my goodness.  

Gin Stephens: Isn't that fun? Now, I've met all of them face-to-face.  

Melanie Avalon: That's so crazy. That was a fun game. I like guessing games.  

Gin Stephens: I know you do. That's why I was happy to do it because I was like, "Melanie's going to like this." You did a good job and you've got all of them. [laughs] And they're all just lovely. That's the best thing.  

Melanie Avalon: That's what I was reflecting on. Because I was posting about it on my Instagram today, and I was just reflecting on how it's all really, really wonderful people. Literally, it's my closest friends now, not necessarily that group that we just mentioned but-- 

Gin Stephens: The conference that I went to where I met all of them face-to-face, you know, JJ Virgin puts it on, and it is the best community of people. You know, the people that you know from your podcast are all probably very in the same circle. I really think JJ Virgin has a lot to do with that because she has a philosophy of, we should all work together and lift one another up, and like a rising tide lifts all ships and that everyone works together, and that we're not in competition, we're in collaboration.  

Melanie Avalon: Oh, that's definitely the way I feel it.  

Gin Stephens: That's exactly the way this whole community feels. So, everyone is a generous supporter of everyone else. Even if you don't have the same philosophies about things, people talk about them respectfully together, and it really is just an amazing group that she has put together and cultivates. 

Melanie Avalon: I think that's so important. I also, think there's often, I don't think it's necessarily true but there's this cultural idea that like women in particular get competitive when it comes to business rather than collaborative, and yeah, that just doesn't resonate with me.  

Gin Stephens: Yeah. And the whole idea that we can disagree about things and still like each other. I'm talking to in a big general, not like just me and you. But in a general world of like the health world.  

Melanie Avalon: Oh, yes.  

Gin Stephens: Like Wade Lightheart and his partner that eat differently. We've talked about them a lot but that you can have different philosophies and still collaborate. Anyway, I just love it.  

Melanie Avalon: I do, too. I have one more update. I can't say what it is yet exactly.  

Gin Stephens: That's a fun one. No, I'm kidding.  

Melanie Avalon: I know. But I just want listeners to know that I'm really getting closer to currently developing a supplement number two and it's very exciting.  

Gin Stephens: Oh, here's the funny story. Can I tell you a funny story about supplements?  

Melanie Avalon: Yes.  

Gin Stephens: I was telling Chad about your supplement and how great it was going. I'm like, "I'm never going to make a supplement." He's like, "What do you mean?" Because he's a medicinal chemist. [laughs] So, I actually have someone living in my house who probably could formulate a supplement. He's like, "What do you mean? We could make a supplement." I'm like, "I don't want to make a supplement." He's like, "But we could. We could do that." He's at the point. He just found out he can retire after one more semester. He can retire and start drawing retirement. He's not sure if he's going to. He hasn't decided but he can. So, he might be like, "Let's make some supplements." I'd be like, "Oh, okay, you're in charge of that, Chad." But after I've always said, I wouldn't, I'm still not planning to but the way he reacted was just so funny.  

Melanie Avalon: That's really funny.  

Gin Stephens: He's like, "I could do that." I mean, he totally could. Drug design is his thing but [laughs] he's going to have to be 100% in charge. It'll be Chad not me. I don't really want to make supplements. But I'm glad it's going well for you.  

Melanie Avalon: It's going so well. It's just so fun and I said this before, but it's just really exciting to see this concept manifest in real life and for it to work so well. Oh, my goodness, so, the supplement, I haven't mentioned the one out right now, which is serrapeptase. I think, I've mentioned before that I have this mole on my nose that won't go away that I keep getting it like lasered off or shaved off and it keeps coming back. I was wondering if the serrapeptase would do something, but I think it's actually going away now.  

Gin Stephens: Okay. Well, then I've got to get your serrapeptase and take it because I've got an eyebrow mole and I need that eyebrow-- It drives me crazy. The hair grows straight out of it like a witch's mole. I mean, so, I have to pluck it. Like right in the middle of my eyebrow, I have to pluck all that hair out, and then, I have a bald spot in the middle of my eyebrow. It could be worse, right?  

Melanie Avalon: So, it's colored? Like it's brown?  

Gin Stephens: No. It's skin color. It's a skin color mole.  

Melanie Avalon: Okay, yeah. That's what mine is, too.  

Gin Stephens: Yeah. But it is right there in the very middle of my eyebrow, and the hair that grows out of it right there just sticks straight out like crazy. One day when I'm really old, I'll just let it go. I won't care.  

Melanie Avalon: Well, maybe you can try my serrapeptase and maybe it will. 

Gin Stephens: I need to. Does that make my mole go away then that would be amazing?  

Melanie Avalon: That would be so exciting.  

Gin Stephens: So, I will never do a supplement because you'll have all the supplements. So, I don't need to. 

Melanie Avalon: I think, I definitely know my next five that I want to do. So, when this episode comes out, we're doing a holiday special. Okay, we're logging down the details probably tomorrow. So, this might change. But what I think it's going to be is, I think, it's going to be 25% off which is crazy. So, 25% off, and then, I think, it's going to be that if you order it while it's 25% off, then you get like a special link. You can send to your friends, and then, if they use that link, they get 20% off of a future order, and you also get 20% off for every friend that purchases. It's like refer a friend thing. So, that's all at avalonx.com, and then my email list for information about the future supplements, and then, like that special and all the things is melanieavalon.com/serrapeptase. S-E-R-R-A-P-E-P-T-A-S-E. So, yeah, and last thing, do you know what I really want to develop Gin, I guess, it would be under my supplement line, but it's not a supplement that you take internally.  

Gin Stephens: I don't know if I could ever guess.  

Melanie Avalon: I want to make a fasting fat unlocking cream.  

Gin Stephens: Okay. What? You're going to have to explain it. I'm so confused. [laughs] I feel like fasting just unlocks the fat already.  

Melanie Avalon: Well. Okay, so, a lot people have stubborn fat. It's often subcutaneous fat. So, it's like that fat that you can pinch. So, love handles, and maybe on your arms, or on your abs. So, yes, fasting puts you into a fat burning state and encourages fat burning but a lot of times those actual fat cells, there's receptors on fat cells that basically determine whether or not they are releasing their fat or storing their fat. Even if you're fasting, fasting does not necessarily mean that you'll automatically, easily open up all your fat cells to be used. Especially, depending on their metabolic state and where they're at like people who you know, yo-yo diet, I think, the more you lose and regain, and lose and regain fat, the more resistant your fat cells come to losing their fat again. So, if you literally put a compound into the fat cell topically that activates receptors that encourages the fat cells to release their content, then, I think, you can more easily burn stubborn fat while fasting. So, it's like upgrading your fasting, like if people were to drink coffee and find that that helps them burn more fat.  

So, there are different compounds that do this like caffeine, and menthol, and green tea, and I found one that I currently use, and I like the ingredients mostly, but it's not completely clean, and I just want to make one that has no problematic ingredients and just these active ingredients, and I think, it can go two ways people who have really stubborn fat and maybe a lot of it, it can help that for sure. But also, people who don't even necessarily need to lose weight, but they have like, just it seems little stubborn areas, I think, it can really, really benefit that while fasting. So, it would be a fat unlocking cream. It wouldn't actually burn any fat, but it would make it easier to burn, to spot treat fat burning while fasting.  

Gin Stephens: All right, well, that's interesting.  

Melanie Avalon: That's my pitch. [laughs] I'm so excited. Yeah, I'm inspired because the one I've ordered is actually, I'm a bit shocked how well it's working, but it has stuff in it that I don't like. So, I've got to make my own version.  

Gin Stephens: Well, it's fun to know connections so that you can make things that have just the ingredients you want in them.  

Melanie Avalon: Yeah, definitely. Like the one I'm using right now is like bright blue. I'm like, well, it was not good, dyes and stuff like that.  

Hi, friends. Okay, we have thrilling news about Joovv. They have new devices and we have a discount. Yes, a discount, no longer a free gift, a discount. As you guys know, there are a few non-negotiables in my personal daily routine. I focus on what and when I eat every single day and I also focus on my daily dose of healthy light through Joovv’s red light therapy devices. Guys, I use my Joovv all the time. Red light therapy is one of the most effective health modalities you can use in your home. I've personally seen so many health benefits, I find it incredible for regulating my circadian rhythm, helping my mood, boosting my thyroid, smoothing my skin, and I've also used it on multiple occasions for targeted pain relief. Anyone who's familiar with red light therapy, pretty much knows that Joovv is the leading brand. They pioneered this technology and they were the first ones to isolate red and near-infrared light and make it accessible and affordable for in-home use.  

Since then, they've remained the most innovative, forward-thinking light therapy brands out there. And we're so excited because Joovv just launched their next generation of devices and they've made huge upgrades to what was already a really incredible system. Their new devices are sleeker, they're up to 25% lighter, and they all have the same power that we've come to expect from them. They've also intensified their coverage area, so you can stand as much as three times further away from the device and still get the recommended dosage. They've also upgraded the setup for the new devices with quick, easy mounting options, so your new Joovv can fit just about any space. And the new devices include some pretty cool new features, things like their Recovery Plus mode, which utilizes pulsing technology to give yourselves an extra boost to recovery from a tough workout with rejuvenating near-infrared light.  

And this is my personal favorite update. So, for those of us who like to use do devices to wind down at night, they now have an ambient mode that creates a calming lower intensity of light at night. Guys, I am so excited about this. Using this light at night is way healthier than bright blue light from all of our screens, and much more in line with your circadian rhythm. I was using my current Joovv devices at night anyway to light my whole apartment, so this new ambient mode is really going to be a gamechanger for me. Of course, you still get the world-class customer service from your helpful, friendly Joovv team. So, if you're looking for a new Joovv device for your home, we have some very exciting news. You can go to joovv.com/ifpodcast and use the coupon code IFPODCAST. You'll get an exclusive discount on Joovv’s newest devices. Yes, discount, I said it. That's J-O-O-V-V dotcom, forward slash, I-F-P-O-D-C-A-S-T. Exclusions apply. And this is for a limited time only. And we'll put all this information in the show notes. All right, now back to the show. 

Melanie Avalon: Shall we jump into everything for today?  

Gin Stephens: Yep, let's get started.  

Melanie Avalon: All right. So, to start things off-- Oh, I don't think I even realized this was from a Melanie.  

Gin Stephens: I've actually met this Melanie face to face.  

Melanie Avalon: Oh, really?  

Gin Stephens: Yes. She was on my podcast. So, I wonder when she sent this one in, it might have been like a long time ago. It might be an old one because I've met her face to face and she was on my podcast.  

Melanie Avalon: Oh, nice.  

Gin Stephens: I know.  

Melanie Avalon: Well, hello, Melanie. The subject is: "Episode number 1 and eating earlier." So, Melanie says, "I just listened to my first IF podcast." So, she had just listened with this had been a while ago, you think?  

Gin Stephens: Well, I don't know. I don't know because I don't know when people listen to Intermittent Fasting Stories, and then, they might run out of those, then, they start Intermittent Fasting Podcast, so, it's hard to know. The question that she asked about me makes me feel like maybe this was before. You'll see when you keep reading it.  

Melanie Avalon: So, she says, "It was fantastic. I really enjoyed it." And this is a question we get a lot. She says, but where is Episode 1, on iTunes, it starts as number two. Yes. There is no Episode 1. We had technical difficulties with it and it's lost forever. I don't even know. Yeah, it's lost. [laughs] I'm sorry. It's funny. Sometimes, I think, occasionally we've had a question where they say, they actually heard Episode 1, and that's how you know they've been there since day one. Her second question. She says, "Gin was talking about how if there is a family gathering i.e., brunch she eats earlier. Does she still follow up with a five-hour rule and stop eating after five hours no matter what time of day it is? Thanks, and again loved my first episode, you both sound great together." She's from Canada. 

Gin Stephens: Yep. And this is why I think she probably knows the answer to this now. But the answer is, of course, probably, people who've been listening a long time know that I do not time my window anymore at all. For example, yesterday, I had brunch with Will. It actually wasn't very early we went at 2. There's this place down here they have this jazz brunch, and it's fantastic, and I love to go there. It's called LOCAL. It's in Pawleys Island. If anyone's ever down in the Pawleys Island area, go to LOCAL, I love it. They made me a mocktail, I had eggs Benedict, we split avocado toast, we listened to jazz, yum. But it was 2 o'clock. And then, if I was still following the 5 o'clock rule, I would be like, "All right, must stop eating by seven." Nope. [laughs] I no longer do that at all. I just go with the flow depending on what day it is and what's happening. There are many days that my window is shorter.  

For example, let's see what day is it. Today's Sunday. We're recording. We came to the beach. Okay, Wednesday and Thursday--, both Wednesday and Thursday, I was busy. So, I didn't eat until later probably, 6:00, 6:30, something like that. I had dinner, closed my window less than an hour, two days in a row. Then, I've had a couple of days right after that with longer windows. So, I feel like it all balances out. I would really be, I mean, of course, I don't track it. It would be interesting to see what my average is. I bet my average is probably five hours or less but I don't even know. So, I no longer track anything. I just wait till I open my window and then I close it when I'm done whatever that may be. 

Melanie Avalon: When you're tracking, would you adjust for that?  

Gin Stephens: Well, when I was trying to lose weight, see that was a different thing. When I was trying to lose weight, I was following Dr. Bert Herring's Fast5, and he had 19:5 as the foundation of his plan. And his one rule is, find a consecutive five-hour window every single day and stick to it. That was the only rule. It needed to be a consecutive five-hour window. And he didn't even talk at all about tracking the fast. It was like, you have that, the boundaries of the five-hour window, you open, you close it within five hours. He's like, "Of course, you're going to have some days where it's longer, some days were shorter, but in general, five-hour window." So, that's the way I was raised up my early days with the Fast-5 program. So, when I was losing weight, that's what I tried to stick to.  

Melanie Avalon: When you were doing that, if you had opened it earlier, you would just do it earlier five-hour window?  

Gin Stephens: Yes. But that didn't always work so well. People have heard me talk about this before, when I open early, even if I have a giant brunch at noon, a giant meal. Let's say, I have a Thanksgiving dinner at noon.  

Melanie Avalon: All right. 

Gin Stephens: I'm probably going to feel great till about 8 PM. It is just about what I've noticed for myself. So, I'm like, "I'm just going to eat this one big meal, and then, I'll be fine. And then, I'm fine, I'm fine, I'm fine, I'm fine." 8 PM rolls around, I'm starving. So, I have two options at that point. I can be like, "I'm just going to push through the hunger and go to bed." But I don't do that. If I'm starving at 8 PM, I eat again. I don't like to go to bed starving. That's not the right answer for everybody. Maybe someone else push through. But it's easier for me to push through, after I wake up in the morning, fast longer than it is for me to push through in a day when I've closed my eating window, and now, I'm starving again.  

Melanie Avalon: We talked about this, but I'm the exact same way-- The exact same way. All right. Shall we go on to our next question?  

Gin Stephens: Yes. And this is from Angela, and the subject is: "Processed versus plant-based." She says, "Hi, hello, Melanie and Gin. I am a 33-year-old female who has been experimenting with intermittent fasting since November of 2019. I lost a total of 20 pounds between November and December of 2019 and have over 50 more to go. Then, I slowly went back to my old ways in February, but never fear I'm going to continue IF immediately. It is the only thing I have found that has helped combat my chronic fatigue in addition to weight loss. So, we know that processed foods aren't the best for our bodies and Whole Foods provide more nutrition. My body doesn't do well with most meats. I can have very lean meat and fish. So, I've been looking into incorporating plant-based foods into my diet. My question is kind of threefold. First, if I am eating pre-processed, pre-packaged plant-based foods, is it counterproductive to try to increase nutrition?" It's never counterproductive to try to increase nutrition. I'm just going to say that.  

Melanie Avalon: I agree.  

Gin Stephens: Although, we can talk about the first part in a minute, but it's never counterproductive to increase nutrients. All right. "Second, what should we be looking for so far as no added this in plant-based products? Last, are there any plant-based foods or food brands that you can recommend? Thank you, ladies for all that you do. You bring so much inspiration and information to us all and all I can say is," she's going to love Clean(ish). Angela needs to read Clean(ish), because it's all explained in there. So much detail. But anyway, you get to go first, so, I'll let you talk about it first.  

Melanie Avalon: All right. So, this is a great question from Angela. This definitely in my opinion touches into something that I see a lot now, especially, with the plant-based food movement, which is where a lot of people are making the dietary choice for health, or environmental, or ethical reasons to go plant-based, which can be really great for the individual depending on the individual's constitution. But there are a lot of like Angela said, you know, pre-processed, pre-packaged plant-based foods that may come with their own array of issues.  

Gin Stephens: Like Girl Scout Thin Mint cookies. I think, they're vegan. [laughs] So, yeah, they call something vegan and you're like, "Oh, it's so healthy." No, it is a Girl Scout Thin Mint cookie.  

Melanie Avalon: Yeah. I mean, think about how many just like of the breakfast cereals on the market are probably technically vegan. Sugar is vegan. Yeah, so, a lot of things. I did a lot of research on this, by the way for brands and stuff, the different thoughts. There is the option of less processed, less pre-packaged plant-based foods. So, you could still be making meat alternatives yourself and I know that might require more time, but once you figure out the system that works for you and how to cook it and what you like and integrate it into your life, I think, the cost benefit of learning how to make food closer to its natural form that you really like long term in the health world will have massive, massive benefits. So, if that's an option, I would definitely go that route. So, that would be things like, if you are eating soy or tofu, getting that more plain and cooking it the way you like or things like mushrooms or-- Did she say, she's vegan or vegetarian?  

Gin Stephens: She just said plant-based. 

Melanie Avalon: Oh, she does have lean meat and fish. So, you might be having eggs, and lean meat, and fish. You could still stay in the Whole Foods world and make it work plant-based wise. If you are having more of the pre-processed, pre-packaged plant-based foods, things you would want to look for, it's really, really shocking. If you turn over most of the things in the market and see the ingredients, there's just so much stuff. So, things I would look for are anything you can't pronounce or don't know what it is, that's probably not the best sign. A lot of like gums and carrageenan are added to these foods, and those can be problematic, they can be inflammatory. If it ever says like natural flavors that can be anything, so that's a little bit sketchy.  

Gin Stephens: It could be MSG. They hide that under all sorts of flavor kind of things. 

Melanie Avalon: Something I personally am very concerned with is refined seed oils, and I've done an episode with Dr. Cate Shanahan all on this. If you'd like to learn more, that's at melanieavalon.com/fatburnfix. But that's all about the potential problematic issue of refined added vegetable and seed oils. So, that's vegetable oil and there's like you can remember it because there's three C's three S's, there's probably more but that's a way to remember the main ones. So, it's canola, corn, cottonseed, soy,- 

Gin Stephens: Sunflower. 

Melanie Avalon: -sunflower? Yeah, sunflower. I would be really wary of those in the foods. The ironic thing about it is that, a lot of the vegan and vegetarian foods will actually use these oils because it's a way for them to have less saturated fat, and it works for them, and what they're trying to make the label say. But the problem with these oils is they are highly, highly unstable. So, when they are refined like that and then in these foods, they can really create a lot of inflammation in the body and oxidative issues. So, I would really, really avoid added C in vegetable oils. If you are having soy which is going to be pretty prevalent in the plant-based world, the majority of soy is GMO. So, I would look for organic soy only. My thoughts on soy have been changing. So, I've always sort of historically been on the fence and a little bit confused, and I didn't do a really, really deep dive until pretty recently because I interviewed Dr. Neal Barnard, who is one of the top vegan proponents of all the vegans.  

A lot of listeners probably know who he is because he's in all the documentaries, he has a lot of books. I interviewed him finally, like two weeks ago. So, that episode I think will come out around March or so. He wanted to come on actually for his study about soy. So, ooh, I went deep. I read everything I could find and my takeaway was that-- we've talked about this on a recent show, so I won't go too deep into it. But my takeaway was that, it's probably very context dependent. It probably depends on your gut microbiome, it probably depends on your genetics as to whether or not you benefit. I think, it might depend on your current estrogen burden. But in any case, I think, going the natural route, so, non-GMO, organic soy and/or like fermented soy, which is called tempeh would be the route to go if you go that route. So, yes. So, my suggestion would be to turn over, go to like Whole Foods, and look at all the brands, and turn them over, and see what's in them. I will list some brands that I like.  

So, Primal Kitchen does make some vegan, and like non-dairy condiments and things like that. So, you could check them out. Check out Amy's. If you're sensitive to gluten, that's something that you would want to be looking for. So, any grains or gluten and the products. I like Eden Foods. That's a brand they make some soy milks, and soups, and they're mostly organic, no additives or they might be all organic. A good dairy alternative is coconut milk but it's pretty hard to find coconut milk without gums and carrageenan, but I know they do have one at Trader Joe's and Native Forest is also a brand. If you're going with the vegan milk still, it's like almond milk, it's really hard to find one without additives, but MALK is a brand that doesn't have any problematic ingredients, For the soy, SoyBoy is a brand that I like. They have soy and they have a Tempeh.  

Again, check their ingredients though because some of the different flavors have problematic additives. There's a meat alternative made from jackfruit and Upton's makes an original form that doesn't have any additives. So, that's something that you could try. You can also get organic canned jackfruit. So, that might be something to cook with. Mushrooms, by the way, are also fun things to add and use as meat alternatives. Especially, the really big like portabella mushrooms. I like some of this Dr. Praeger's that they have at Whole Foods, but it's not organic is the only thing. Maybe that's a place to start but I would definitely either way, there's going to be like, if you really want to invest in this, there's going to be a learning curve, where you are going to just need to familiarize yourself with brands, and then also, like I said maybe learn how to make vegan or vegetarian plant-based alternatives yourself in a more whole foods form. 

Gin Stephens: I have a few things to add, although, you've said a lot as usual, which is good. [laughs] You are thorough, that's the word I'm looking for. So, I really think like I said, Angela, you're going to love Clean(ish), because it can get really hard to decide, you know, how perfect do you want to be? That's where the ish comes in. We know for certain but there's a lot of stuff we don't know for certain in the health world. You'll find a study that says one thing, you'll find something else that says something contradictory, but I will pretty much say, Melanie, see if you agree with me here. We know for certain that no one gets healthier by increasing the amount of ultra-processed foods in their diet. Would you say that's pretty much one thing we know for sure?  

Melanie Avalon: No one gets healthier by increasing ultra-processed foods. I don't like to ever say I'm certain about anything.  

Gin Stephens: I know. I don't either. But this is one where I'm pretty certain. 

Melanie Avalon: That is the closest to approaching certain that I can get.  

Gin Stephens: I've never seen a study that implied otherwise, more and more, ever since the term ultra-processed came out, which really hasn't been very long. I talk about this a lot more detail like I said in Clean(ish). We used to just say processed, but that is a misleading term. Because if you shuck an ear of corn and slice it off the cob and cook it, you've just processed it. But if you grind your wheat into flour, you just processed it. So, processing itself is not a bad thing. It's the ultra-processed, that's the problem. Once we got that terminology, it really helped make things clear. You want to eat things that are not ultra-processed when you can. But again, I'm cleanish. Melanie just listed a whole bunch of options that are probably considered to be ultra-processed but still better than other options that are ultra-processed. Feed foods can be organic, and also ultra-processed at the same time. We think that if it says organic on the label, it's a good choice. Those organic seed oils are just as inflammatory to me. I mean, maybe not just as inflammatory, maybe the ones that are not organic or would be less inflammatory, but they are inflammatory as well.  

There's a term that I learned when I was at the Institute for Integrative Nutrition called crowding out. It's a great concept. It really helped me come up with my own personal definition of Clean(ish). You want to focus on high-quality Whole Foods, whether you're looking at the paradigm of plant-based or whether you're going to be paleo. Melanie, you know for sure that as paleo got popular, paleo ultra-processed foods became available, which is the opposite of what paleo was supposed to be.  

Melanie Avalon: Yes, I was going to say that exactly.  

Gin Stephens: Right. So, we can ruin anything in America or the world by ultra-processing it and it still quote fits the guidelines, but it doesn't at all. I've talked about this before as well when I did the low-fat diets of the 90s, I read the T-Factor Diet and the only takeaway that I took away from that was eat less fat. So, I started eating SpaghettiOs, and SnackWell's, and McDonald's had a fat free Apple muffin, you could drive through and get and you could have a coke with that and the whole thing was fat free. I mean, that is not what the T-Factor book said to do. I went back through it recently and reread it, and he wants you to eat whole foods that are low in fat. That's really what it is. No matter how you're choosing to eat, the more real foods you can fit in there, the better you're going to be, and over time, you'll figure out, what proportion of ultra-processed foods you can allow in there. Melanie, are you zero with ultra-processed foods, would you say? Do you eat any?  

Melanie Avalon: So, in my everyday day-to-day life, I don't have any. When I go through my low carb phases, that's when I'll do the MCT oil which is ultra-processed. Every now and then if I'm having like a crazy celebratory craving, I will get the low carb like keto cake mixes with the least amount of additives. So, they're typically like almond, or coconut flour and erythritol, or monk fruit or stevia. 

Gin Stephens: Okay. So, you're on the continuum. Really close to whole foods all the time, but you still allow the ultra-processed sometimes. And that's your definition of Clean(ish), right?  

Melanie Avalon: Mm-hmm.  

Gin Stephens: But I on the other hand, I wouldn't choose something with monk fruit or erythritol, I would use real sugar or coconut palm sugar instead. That's because we each have a different what we want to do. That's the whole in the book, Clean(ish), which you need to order right now, because it's coming out January 4th, which is so very soon. In Clean(ish). It's all about figuring out your own personal definition of how that looks for you and what will you have and what will you not? I talk about in there that, I avoid these oils, I like to stick to organic things, but there's a mayonnaise I love that I grew up with and I don't eat mayonnaise very often. So, if I do need to eat mayonnaise or want to eat mayonnaise, I use this brand. It's probably GMO. I'm sure it is full of funky stuff, but I like it. But I don't need it all the time and I don't eat those oils day-to-day. So, it's just like I said, a matter of figuring out your perfect balance. My diet has more ultra-processed stuff in it than Melanie's, but it's way different than how it looked one, two, three, four, 10 years ago. So, it's a process.  

Like I said, before, that I ate out twice yesterday, I am feeling so puffy today and I know, it's because when I eat out, they use all these things, these inflammatory ingredients I don't use at home. So, I don't feel my best. When I get home tomorrow, I'm going to make something that has very high vegetable content, and I'm going to feel better. And it's just a matter of finding that balance that works for you. The more ultra-processed foods you can eliminate, but still enjoy your life, I really think the better.  

Melanie Avalon: To that point for me with eating out like I've just learned how to order where I'm equally happy with what I'm ordering but then I don't get any of the negative effects because I'm so specific in how I order. For some people, it's worth it to do that and for some people, it's not. So, it's really just a matter of like you said, Gin, what's worth it to you and what makes you happiest in the long run. Have you tried Primal Kitchen's, mayo?  

Gin Stephens: Yes, [laughs] and it's good. It's fine. If I were someone who ate mayonnaise every day or used it a lot, then, I would really think about the brand that I use. I would not want the brand of mayonnaise that I prefer. I'd like Duke's mayonnaise, and I grew up with it, and it is what mayonnaise is supposed to taste like. If I want something, it needs to be Duke's mayonnaise. But I don't eat mayonnaise every day. If I did, I would probably switch to Primal Kitchen. But it's a sometimes thing. So, having a little bit of this once a month or however often, I really only put it on if I'm making pimento cheese, which I don't do hardly ever. [laughs] Maybe at Christmas, I'll make my cranberry cheese or I'm having an egg sandwich which I have, I don't know, not even once a month. So, I'm going to eat it it's going to be Duke's, but I don't eat it very often. I don't think I explained what crowding out was. Did I explain what it was or did I just say it and then go down another rabbit hole? Crowding out is when you focus on high-quality Whole Foods as the main part, and then you crowd out, let's say, I wanted to have some homemade hummus with a few pita chips on the side, and then a big salad or something. So, I'm crowding out those chips. I'm still allowing them but I'm filling up on the good stuff first.  

Melanie Avalon: I love that. I will say speaking to the sweetener stuff, I reserve the right to change my opinion on this but the sweetener, I'm most interested by as far as I think it probably has-- 

Gin Stephens: All right, I'm predicting in my head what you might say, go ahead. 

Melanie: Oh, ooh, ooh, yay. I like this game. I think it probably has the most health benefits, minimum side effects. Allulose, all right, that's not I was going to say. What did you think is?  

Gin Stephens: Well, I was thinking you might would think blackstrap molasses was interesting because it's got so much mineral content.  

Melanie Avalon: Yeah, or manuka honey. Pay 100 bucks for a tablespoon.  

Gin Stephens: Exactly. Yeah, exactly. Have you looked at blackstrap molasses at all? 

Melanie Avalon: I've seen vaguely at different times. I know, it has certain things in it nutrient wise. The allulose is really interesting because it's becoming more and more popular. I went and read all the studies that I could find on it, and it actually, it has a very beneficial effect on especially for like diabetics on just carb content in general. I'd have to revisit what I was saying but the mechanisms of action are really interesting. I think, I don't want to put up misinformation, but it's something like it either competes with carbs or it seems to have a pretty beneficial effect, and it tastes very similar to sugar, and it acts very similar to sugar.  

Gin Stephens: To be honest, for me, the reason I avoid all those others is, I just don't like the way they taste. I don't like any of them.  

Melanie Avalon: Have you tried allulose?  

Gin Stephens: I haven't tried that one. 

Melanie Avalon: Oh, that's what it is. I think, it's actually a natural like sugar. That's what it is. It's a natural sugar found in certain fruits but we just literally can't metabolize it into carb energy. So, it's getting sugar without getting any sugar.  

Gin Stephens: Well, they said all about the sugar alcohols, all those things and I just don't like them.  

Melanie Avalon: I know. I agree. It's not a sugar alcohol. No, it's an [unintelligible [00:45:58].  

Gin Stephens: Those are the kind of things they said like, "Oh, it's natural, oh, it's still not like--" [laughs] I would love to try it but I just stick to coconut palm sugar is really good. It's got that brown sugar flavor. Have you ever had it?  

Melanie Avalon: Nope. Do I know a fun fact? Do you know the difference between sweet corn and corn?  

Gin Stephens: I do.  

Melanie Avalon: Oh, like the variety?  

Gin Stephens: Yeah.  

Melanie Avalon: Oh. I just learned this because I'm prepping to interview FARMER LEE JONES. Do you know who he is?  

Gin Stephens: I did not.  

Melanie Avalon: Oh, I'm so excited. He's like this epic regenerative agriculture farmer. He always wears overalls. That's what he's known for. I think, his farm pioneered microgreens, and they're all about creating really interesting varieties, and species, and using all the parts of the plant, and they're just really cool. But I learned in his book, which is epic. Okay, now, going on to some other tangents.  

Gin Stephens: I would probably love his book. What's it called?  

Melanie Avalon: So, his book is called The Chef's Garden: A Modern Guide to Common and Unusual Vegetables -With Recipes. And it came out in April. It is the most beautiful book and it reminds me--, Gin, it reminds me of you so much like what I was reading it. It's really like, "If Gin were to make a, well, actually--"  

Gin Stephens: All right, I'm going to order it right now.  

Melanie Avalon: It's like if both of us were to make this book because-- 

Gin Stephens: Tell me the name of it, again. 

Melanie Avalon: The Chef's Garden: A Modern Guide to Common and Unusual Vegetables -With Recipes. I got so happy because so his people asked to come on the show and I asked if they could send me like the book, and they sent it, and he signed it with a message to me. It made me so happy. So, I have a signed copy but it's a beautiful book and the reason it reminds me of you is the recipes are-- 

Gin Stephens: I just ordered it.  

Melanie Avalon: Oh, yay.  

Gin Stephens: It's coming.  

Melanie Avalon: Let me know what you think when you get it. You'll see why when you get it, but the recipes are all there are whole foods and stuff, but they also use sugar and they're not like--  

Gin Stephens: They're Clean(ish) 

Melanie Avalon: Yeah. It's really an amazing, incredible book. Oh, but I read the whole thing front to cover, which I probably didn't need to do because you will learn so much about every vegetable ever known to mankind.  

Gin Stephens: Well, I can't wait, I'm so excited about that.  

Melanie Avalon: I feel like it should be required reading in a way because the amount of information I learned about, I think, I shared it, did I share about the potato?  

Gin Stephens: I don't think so.  

Melanie Avalon: The fun fact about the potato that I learned from this book?  

Gin Stephens: You said something about corn. First of all, tell me if I'm right. This is what I think like when I said yes, I need the difference and then, I was like, "Maybe, I don't" as I started second guessing myself. This is what I think the differences between sweet corn and corn. Most of the corn they grow is not sweet corn and that is to feed animals. Then, sweet corn is the corn we eat, am I right or is that wrong?  

Melanie Avalon: No.  

Gin Stephens: Okay. That's what I thought. There's something about most of the corn they grow is for animals.  

Melanie Avalon: Most of the corn that we grow is, I think to feed animals.  

Gin Stephens: It's not the kind of corn we eat. It's a different variety of corn. That's not the kind we eat and then the kind we eat I thought was the sweet corn. Okay, so what's the difference?  

Melanie Avalon: So, corn is a grain, sweet corn is a vegetable.  

Gin Stephens: Okay. What?  

Melanie Avalon: I know. It blew my mind.  

Gin Stephens: I don't know about that.  

Melanie Avalon: Do you want hear the potato fact that blew my mind? 

Gin Stephens: Yeah, but I've got to look up this thing about corn and sweet corn.  

Melanie Avalon: Okay. [laughs]  

Gin Stephens: I'm telling you what Southern Living thinks, I'm right and he is not. I just looked up, Southern Living said, "The variety of corn we enjoy eating is called sweet corn, which does not grow nearly as tall as field corn. Sweet corn has a higher sugar content than cow corn and is picked while immature before the sugar has a chance to turn into starch." So, that is exactly what I thought. So, I don't really know what he's talking about. I'm going to have to read this book and figure it out. Sweet corn and field corn, it's different, but it's who's going to eat it. 

Melanie Avalon: Corn can be considered either a grain or vegetable based on when it is harvested.  

Gin Stephens: Okay. Well, that does make sense. Okay, but It's the variety of corn, sweet corn is a different variety than cow corn, right? So, they do let the kind that they're going to feed to the animals dry in the field, and I guess, that's the difference is when you harvest it. Whether you would consider it a vegetable or if you let it dry, then maybe it would be considered a grain. No, we were both right.  

Melanie Avalon: Yeah. So, maybe, that's what he meant like the corn that's fully mature and dry.  

Gin Stephens: We harvest it while it's still considered a vegetable. But if you let it sit in the field, but we don't do that with sweet corn. Sweet corn, we do not let it sit in the field and dry. We harvest it and then we eat it. But the other kind of corn is the kind that is for the animals and they do let it dry in the field. When I looked that up, it was because I was driving around and I'm like, "Why is all the corn looks so bad? Why is it all so dried up?" And then, I searched it, I was like, "Is something wrong with the corn this year?" Then, that's where I learned, "No, that's field corn. They're letting it dry for the animals."  

Melanie Avalon: Okay. So much learned about corn. You're going to love this book. Here's the potato on. Are you ready?  

Gin Stephens: Yes.  

Melanie Avalon: So, the potato became this massive thing when they discovered-- I don't remember when it was like 1,700s. When they discovered that it had a high nutrition value in Europe, it was like a good food source, basically. And it was the royalty people that figure this out. So, they wanted to have it as like a food source for the European population. What did they do to make the people start all growing and eating potatoes?  

Gin Stephens: Well, I don't know.  

Melanie Avalon: They did something. They use some reverse psychology to make the non-royalties like the peasants start growing corn. Do you have any guesses?  

Gin Stephens: Do you mean, potato?  

Melanie Avalon: Potato. Sorry. To start growing potato.  

Gin Stephens: Well, I don't know. You just have to tell me.  

Melanie Avalon: Okay. I am just going to tell you because I played this game at Christmas with my family and it took a long time for them to guess. So, I'm just going to tell you. They planted potatoes in guarded fields, so that the peasants would think the potatoes were like really special and expensive or something worth getting. So, then the peasant would steal the potatoes, and then they started planting themselves.  

Gin Stephens: Well, joke's on you royal people, because potatoes are amazing.  

Melanie Avalon: No, that's what they wanted to happen.  

Gin Stephens: But I know, I know. I know. But they're so good. They were like, thinking they're just for peasants, like wanting the peasants to eat them.  

Melanie Avalon: They wanted to spread potatoes as a food source in general. So, it was like, how do we-- 

Gin Stephens: But they liked them, too.  

Melanie Avalon: Yeah. But it was like, "How do we make the peasants start doing this?" So, they made it seem like they were really exclusive.  

Gin Stephens: All they needed to do is just give them a potato and they would have been in. [laughs] He also talks all about the difference between like yams and sweet potatoes. 

Gin Stephens: I've done some reading about that, too. Does he say that yams and sweet potatoes are not the same thing and that yams are--? I think, yams might be in Africa?  

Melanie Avalon: Yeah. Well, I knew they weren't the same thing but I would go down so many rabbit holes before this being like because I'd be like, "How to identify a yam or sweet potato at the supermarket?" He says, "If you're at a normal supermarket, so not--" 

Gin Stephens: It's the sweet potato.  

Melanie Avalon: Yeah. It's a sweet potato. The yams are only ethnic type. 

Gin Stephens: Super specialty. Yeah.  

Melanie Avalon: Oh, I can't wait for you to get this book.  

Gin Stephens: I apparently know a lot about food already.  

Melanie Avalon: You're going to love it. He has sections on every single vegetable, and then all the different varieties, and some of them, there'll be like 30 varieties. They'll talk about 30 varieties of tomatoes. It's mind blowing.  

Gin Stephens: And then, it'll make me want to have all those varieties, then, you go to the store and it's just the plain old boring ones.  

Melanie Avalon: I know. There is a farmer's market here in Atlanta called Buford's Farmers Market, and I've gone a few times, and I think, they have basically everything. It's crazy.  

Hi, friends. Winter aka sick season is upon us and we all know that this is the time of year to take extra care to protect ourselves from germs and bacteria. Of course, you can do everything, right? Wash your hands, keep your hands away from your face, carry around some hand sanitizer, but you still get sick. That's why you need to protect your body from the inside, not just the out. And you can do that by building up your immune system with some high quality and high strength probiotics. That's why I'm really excited about P3-OM. P3-OM is a patented probiotic that might be the most effective probiotic ever developed. P3-OM fights bacteria and strengthens immunity. It's basically a germ fighting superhero, but it also helps digestion, speeds up metabolism, and increases energy throughout the day which is way more than you might have thought probiotics could do. And just when I thought P3-OM couldn't get any more powerful, I watched a video which you can see at p3om.com/ifpodcast of the probiotic literally breaking down a piece of steak. After I saw that, I was all in. You guys are going to be so amazed, too. Definitely check out that video.  

And here's some more awesome news. You can get 10% off P3-OM right now by going to p3om.com/ifpodcast and typing in the coupon code iFPODCAST10. And here's the thing. If you order it, and it's not everything you hoped for, BiOptimizers support team will give you all of your money back, no questions asked. So, if you want to protect yourself from whatever bug is floating around this year, and take your digestion to a new level, visit P3, the letter OM dotcom, forward slash, I-F-P-O-D-C-A-S-T to get a 10% discount with the coupon code IFPODCAST10. We'll put all this information in the show notes. All right, now back to the show.  

Melanie Avalon: That was a tangent. Shall we move on to our next question.  

Gin Stephens: Yes.  

Melanie Avalon: All right. So, we have a question from Julie. The subject is: "How did I get here?" Julie says, "Hello, I started IF in August 2018, 49 years old, 5'2", 134 pounds. I've always been active, walking, yoga, and elliptical weights, workouts. My body mind and lifestyle adapted quickly to IF, a negative self-talk about weight and food finally subsided. I felt healthy free and in eight months, I was 123 pounds. Fast forward to yesterday having not stepped on the scale in months. Now, 51 years old and I weighed in at 136. I maintain clean fast, little alcohol, healthy eating, and 20:4. Please help. Is it age, cortisol? I have read/heard Gin talk about this in relation to COVID-19. ADF is not for me. So, I just try to keep positive, drink more water, almost a gallon daily, eat healthier, etc., but I don't understand how I got here. IF has worked for me and I'm committed to this way of life.  

My weight gain shows in the mirror, my clothes, and my mind. Negative self-talk has returned and I feel like I did pre-IF. Side note: I am in good health, and my doctor supports IF, and the lower weight range for my size. Blood test for my annual physicals were good, no health or thyroid issues. Do you have ideas on supplements or vitamins? Any support is welcome. Thank you." She wants to know if we reply by email or only respond on the podcast, do we give heads up to listeners. Grateful for your expertise and advice. And we do not usually reply via email. Occasionally, we do. Sometimes, emails come through and we just must address something. But normally, it's surprise on the podcast. [laughs]  

Gin Stephens: Yeah, Kate, you got to listen. Hopefully, you'll hear it. So, Julie. We can't answer the why. We can't tell you because you said, is it age? Could be. A lot of people gain weight as they go through menopause and you're right at that exact age for that. Cortisol? Could be. She's referring to a blog post that I put out in 2020 about the pandemic, and stress, and weight gain because all of a sudden, in 2020, people who were maintaining beautifully with intermittent fasting, and had been for a long time started having sudden weight gain. So, we talked about the stress that comes along with the pandemic and we're certainly not over that. [laughs] The stress continues as things continue to like, "Oh, here's a variant." And yeah, the media pumps us full of fear, and we're living in this constant Loki stress state, day after day. So, I would absolutely not minimize the effect of that and I would just say, so, you've gained-- It looks like, you lost 11 pounds initially, and now you're back up the 11+2 more. So, 13 pounds. So, you went down 11 and then you went up 13. So, I know, it's frustrating, but it really could be. It could be a combination of hormones, menopause, and stress that we're living through right now. So, we can't tell you what it is.  

And also, there are no magical supplements and vitamins that we could say, this is what you need. Boy, I wish there were. I'd make that supplement. [laughs] There was a magical supplement that could make us lose the weight, but there isn't. We've been down that road, all of us have, and you buy them and you saw them on the famous TV doctor who had the different episodes about this magical supplement. I bought everything that was on there. Never once did it make me lose magical weight. Sadly, I wish it had. But it could be so many things. I would really suggest, you might need to be someone who does way more frequently. That might be hard to hear, because I'm someone who doesn't weigh at all, and I haven't weighed for a long time. But if I knew that I had gained weight, and I couldn't figure out why, that scale was really good feedback for me when I was trying to lose weight. It really made a difference. And doing my weekly averaging or using something like happy scale, and really being able to see if you can find what's going on. I'm trying to see what she eats. Did she talk about her diet?  

Melanie Avalon: She just says-- I was actually going to talk about that. Yeah, she says, healthy. 

Gin Stephens: Healthy eating is such a big phrase. You know what, what you think is healthy eating, what I think is healthy eating, what Melanie thinks is healthy eating, what Paul Saladino thinks is healthy eating, there are all going to be different definitions. So, there may be some room to improve in your diet, especially, if you're choosing foods that don't work well for you. I could be eating in a way that fits a lot of definitions of healthy eating, but I'm eating too much of it or my body doesn't like those healthy things. My body would like something else. So, it's really time to tweak if-- You haven't done ZOE, yet? You might really enjoy that, ZOE test. I have a blog post about that ginstephens.com/zoe. You've probably heard me and Melanie talk about it. You also might need to switch it up a little bit.  

I know, you said, you like 20:4 with a four-hour eating window. You don't want to do ADF. You said, it's not for you. Although, I will say, the number of people who have said, I didn't think it was for me, and then I tried it, and guess what? I love it. There are a lot of people who say that. So, you might be surprised. But you could do a mild, not really ADF version, where one day, you have 23:1, and then, the next day you have 18:6 or something. You just keep alternating those. That's a very mild up down, up day pattern and see how that goes. That might be enough to get things going. But there're so many things you could try. Unfortunately, though, like I said before, we can't identify the why of the weight gain. We can just point out some suggestions or some ideas of what it might be.  

Melanie Avalon: Yes, I thought that was great. The healthy eating was actually what I was going to focus in on because I thought it was really interesting that the thing, she asked advice or to adjust the way it is vitamins or supplements, that would be the last, well, not the last thing, but that would not be high on my priority list for addressing weight loss. The foundational things, I believe for addressing weight loss are the actual food that you're eating and when you're eating it.  

Gin Stephens: And you know, that just shows how programmed we are to look for that in a bottle. Because we've been taught here's what you take, and then you will lose the weight, and that's not how it goes. I wish it did.  

Melanie Avalon: Exactly. So, I think the healthy eating, it's really easy to eat what may be healthy eating and maybe healthy eating for you, but healthy eating that will create weight gain. Because if you're eating certain foods that are "healthy," but are promoting fat storage, easily stored as fat and eaten higher than you are burning off every day, then, you're going to gain weight as a necessity of that.  

Gin Stephens: People often think that because we say, don't count calories that we are saying that calories don't count. Calories are a terrible way of measuring what's coming in, what's coming out. But neither Melanie nor I or really anybody that I really trust and follow thinks that you can really just overeat eat, eat, eat, eat, eat and not gain weight. If you eat too much, you will gain weight. So, I'm not saying that's what Julie's doing. But you can overeat in a four-hour window if you're eating like a lot of cheese for example. That's my own little-- [giggles] my nemesis of overeating is usually cheese and dairy products because I love them, but they're easy to overeat.  

Melanie Avalon: And that's an example we're looking at the type of food rather than the calories or even the amount can take care of itself in a way. Because if cheese is a greenlit food for you, you can most likely very easily overeat it and gain weight from it. Same with like nut butters and things like that compared to with, you know, you're like, "Oh, I can have unlimited protein." It's unlikely you're going to eat so much protein that you gain weight if anything. It has high thermogenic effect, if anything, you'd probably get full faster and probably lose weight and while also boosting your metabolism for example. So, I would focus in on that healthy eating, and look at what you're eating, and I would suggest, and I say this a lot, so, I feel like a broken record. But if you're not looking at your macros at all, there's a lot of magic that can happen. You don't have to count calories, you don't have to count even amounts, but if you play around with a macro approach that can work really, really well for a lot of people, and it doesn't have to be forever, but it can be just while you're losing this weight. So, that would be either low carb or low fat, and seeing how that works for you.  

Gin Stephens: Yeah, that's a good suggestion.  

Melanie Avalon: Well, this has been absolutely wonderful. So, a few things for listeners before we go. If you'd like to submit your own questions for the show, you can directly email questions@ifpodcast.com or you can go to ifpodcast.com and you can submit questions there. The show notes for today's show will be at ifpodcast.com/episode245. You can get all the stuff that we like at ifpodcast.com/stuffwelike and you can follow us on Instagram. I am @melanieavalon, Gin is @ginstephens. All right. Anything from you, Gin, before we go?  

Gin Stephens: Well, I guess, I'll just put in one more plug for go ahead and pre-order Clean(ish) if you haven't already.  

Melanie Avalon: Yes. 

Gin Stephens: It's coming out really soon and I'm excited. 

Melanie Avalon: Really soon when this airs.  

Gin Stephens: Yes. And even really soon. 

Melanie Avalon: Five or six days, like a week. Like a week after this. 

Gin Stephens: Even really soon like now. It's really soon just in general.  

Melanie Avalon: Yeah. I think, it's about a week after when this airs. Already well, we'll put a link to that in the show notes. And this has been absolutely wonderful and I will talk to you next week.  

Gin Stephens: All right, talk to you then. Bye.  

Melanie Avalon: Bye.  

Melanie Avalon: Thank you so much for listening to the Intermittent Fasting Podcast. Please remember that everything discussed on the show is not medical advice. We're not doctors. You can also check out our other podcasts, Intermittent Fasting Stories, and the Melanie Avalon Biohacking Podcast. The music was composed by Leland Cox. See you next week. 

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Gin: GinStephens.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know! 

 

 

Dec 05

Episode 242: Breaking Fast For The Best Digestion, Live Podcasts, Talk Shows, Early Weight Gain, Endurance Sports, Feeling Too Full, Morning Sickness, PMDD, Hormone Regulation, And More!

Intermittent Fasting

Welcome to Episode 242 of The Intermittent Fasting Podcast, hosted by Melanie Avalon, author of What When Wine Diet: Lose Weight And Feel Great With Paleo-Style Meals, Intermittent Fasting, And Wine and Gin Stephens, author of Delay, Don't Deny: Living An Intermittent Fasting Lifestyle

Today's episode of The Intermittent Fasting Podcast is brought to you by:

INSIDETRACKER: Get The Blood And DNA Tests You Need To Be Testing, Personalized Dietary Recommendations, An Online Portal To Analyze Your Bloodwork, Find Out Your True "Inner Age," And More! Listen To My Interview With The Founder Gil Blander At melanieavalon.com/insidetracker! Go To insidetracker.com/melanie And Use The Coupon Code MELANIE25 For 25% Off All Tests Sitewide!

To submit your own questions, email questions@IFpodcast.com, or submit your questions here!! 

SHOW NOTES

INSIDETRACKER: Go To Insidetracker.Com/Melanie And Use The Coupon Code MELANIE25 For 25% Off All Tests Sitewide!

BEAUTYCOUNTER: Keep Your Fast Clean Inside And Out With Safe Skincare! Shop With Us At MelanieAvalon.com/beautycounter, And Something Magical Might Happen After Your First Order! Find Your Perfect Beautycounter Products With Melanie's Quiz: melanieavalon.com/beautycounterquiz
Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

Stay Up To Date With All The News About Melanie's New Serrapeptase Supplement At melanieavalon.com/serrapeptase Or Head Straight Over To avalonx.us To Place Your Order Now!

Listener Feedback: Andrea - Thank You!

Listener Q&A: Sally - Best Type Meal To Eat When Breaking Fast

Listener Q&A: Paul - You Guys

Listener Q&A: Phoebe - IF & Weight Gain

Listener Q&A: Ashley - Windows, Endurance Sports, Leaning Out

Get 10% Off With Coupon Code MelanieAvalon at Platt Wellness Center!

Listener Q&A: Jennifer - Feeling full

Listener Q&A: Carla - Hormones

TRANSCRIPT

Melanie Avalon: Welcome to Episode 242 of The Intermittent Fasting Podcast. If you want to burn fat, gain energy, and enhance your health by changing when you eat, not what you eat with no calorie counting, then this show is for you. I'm Melanie Avalon, author of What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine. And I'm here with my cohost, Gin Stephens, author of Fast. Feast. Repeat.: The Comprehensive Guide to Delay, Don't Deny® Intermittent Fasting. For more on us, check out ifpodcast.com, melanieavalon.com, and ginstephens.com. Please remember, the thoughts and opinions on this podcast do not constitute medical advice or treatment. So, pour yourself a cup of black coffee, a mug of tea or even a glass of wine, if it's that time, and get ready for The Intermittent Fasting Podcast. 

Hi, friends. I'm about to tell you how you can get 25% off one of the most amazing resources to charge of your health. Do you feel like every day, there's a new wellness trend, eat that, do this, avoid those? Just the other day in my Facebook group somebody posted, saying how they were confused about all of the expert advice out there. It seems like the only thing left that's approved is water. How do you know where to start or who to trust? I am obsessed with a company called InsideTracker. They're a David Sinclair partnered company, and they cut through the noise by analyzing your blood, DNA, lifestyle and fitness trackers to provide you a personalized science-backed trackable action plan on how to live, age, and perform better. InsideTracker is simpler, cheaper, and more convenient than traditional blood tests. 

I interviewed the founder Gil Blander on my show, I'll put a link to it in the show notes. What is so amazing about InsideTracker is that their blood tests, include the biomarkers that you need to be testing that are key to performance that you don't get from traditional blood tests. These are things like ferritin, vitamin D, GST, which is a liver enzyme that you will rarely ever see on a blood test. My favorite part, they don't just give you the data, they provide you with nutrition and lifestyle tips to take action. They also can track your inner age. Basically, how old you really are based on your blood markers. 

InsideTracker’s advanced data driven model first calculates your biological age, then they provide an action plan of science backed recommendations with the goal of improving the quantity and quality of the years ahead of you. They also have this amazing online portal where you can keep track of all of your InsideTracker blood tests and upload your own blood tests from your conventional doctor to keep everything in one place. What I really love is that they analyze your blood work by the ideal ranges, not the conventional ranges that you might see on your normal blood tests. Basically, they give you true clarity and insight into where you're at with your health.  

I am so honored because InsideTracker has the biggest discount pretty much anywhere with us specifically. I mean this. You can go to insidetracker.com/melanie and use the coupon code MELANIE25 to get 25% off sitewide. That's insidetracker.com forward slash M-E-L-A-N-I-E with the coupon code MELANIE25, to get 25% off sitewide. We'll put all this information in the show notes. 

One more thing before we jump in. Are you fasting clean inside and out? Did you know that one of our largest exposures to toxic compounds, including endocrine disrupters, which mess with our hormones, obesogens which literally cause our body to store and gain weight, as well as carcinogens linked to cancer is actually through our skincare? Europe has banned thousands of these compounds for being toxic, and the US has only banned around 10. It's honestly shocking. When you're putting on your conventional skincare makeup, you're likely putting toxic compounds directly into your body. These compounds can make you feel bad, can make it really hard to lose weight, can affect your hormones, your mood, your health. And ladies, if you're thinking of having kids, when you have a child, these compounds actually go directly through the placenta into the newborn. That means your skincare makeup that you're putting on today actually affects the health of future generations.  

Did you know that conventional lipstick for example often tests high for lead, and the half-life of lead can be up to 30 years in your bones? That means when you put on your lipstick, 30 years later, half of that lead might still be in your body. Thankfully, there's an easy, easy solution to this. There's a company called Beautycounter and they were founded on a mission to change this. Every single ingredient and their products is extensively tested to be safe for your skin, you can actually feel good about what you put on. And on top of that, their products actually work. That's because they're not “all natural.” They actually combined the best of both worlds, both synthetic and natural ingredients, to create products that actually support the health of your skin and make your skin look amazing. They have skincare lines for all your skin types, deodorant, shampoo and conditioner that I love, anti-aging and brightening peels and vitamin C serums, and incredible makeup. If you see my makeup on Instagram, that's all Beautycounter. You can shop with us at melanieavalon.com/beautycounter 

And if you're thinking of making safe skincare a part of your future, like we have, we definitely suggest becoming a Band of Beauty member. It's sort of like the Amazon Prime for clean beauty. You get 10% back in product credit, free shipping on qualifying orders and a welcome gift that is worth way more than the price of the yearlong membership, totally completely worth it. Also definitely join my clean beauty email list at melanieavalon.com/cleanbeauty, I give away a lot of free things on that list and join me on my Facebook group, Clean Beauty and Safe Skincare with Melanie Avalon. I do a weekly giveaway every single week for Beautycounter, people share their experience and product reviews, and so much more. And again, the link to shop with us is melanieavalon.com/beautycounter. All right now enjoy the show.  

Hi, everybody and welcome. This is Episode number 242 of the Intermittent Fasting Podcast. I'm Melanie Avalon and I'm here Gin Stephens. 

Gin Stephens: Hi everybody.  

Melanie Avalon: How are you today, Gin?  

Gin Stephens: I'm doing great. How about you?  

Melanie Avalon: Guess what I am holding in my hand.  

Gin Stephens: Water?  

Melanie Avalon: No.  

Gin Stephens: [laughs] Because you just said you're going to drink some water before we started recording. So, I just assumed.  

Melanie Avalon: Well, I do have water. Guess what type of water the water is? 

Gin Stephens: Oh, Lord, I don't know. Some kind of weird wacky water? 

Melanie Avalon: Deuterium depleted.  

Gin Stephens: I knew it. I knew it was going to be that one. I'm holding a mug of hot water, some [unintelligible [00:06:38]. 

Melanie Avalon: Oh, man.  

Gin Stephens: So, I'm going to guess that you're holding your Serrapeptase?  

Melanie Avalon: I am.  

Gin Stephens: I knew it.  

Melanie Avalon: It's so beautiful.  

Gin Stephens: Have you taken any yet?  

Melanie Avalon: Yes, I have. So, it came yesterday that like the box of my samples. Oh, the samples, that means I can finish the trademark registration. So, last night, I got the bottle and I tried it for the first time, and it was great. No GI issues. That's one thing I was a little bit worried about was GI distress because Serrapeptase doesn't really have side effects. But that is the one thing that is sometimes reported, but it felt amazing. My brain felt so clear after, and I took some today and the same thing. I'm so excited. And then I was chatting with my business partner. And he-- wait, did I tell you this already? He put one-- 

Gin Stephens: Oh, in the vinegar, yeah.  

Melanie Avalon: Yeah, I told you that last time. So, I'm excited.  

Gin Stephens: Yay. It's good to see a plan come together.  

Melanie Avalon: It's so interesting to see an idea manifest in its physical form in front of you.  

Gin Stephens: It really is. It really, really is to know that you could do this. I was always a big dreamer as a kid, like I had all these ideas and I was like, “I'm going to do this. And I'm going to do that.”  

Melanie Avalon: Me too.  

Gin Stephens: I believe it. And you're like, “Wow. Look, we did these things.”  

Melanie Avalon: I know, you really can. When listeners get it, the logo, the Avalon X logo. The Avalon is my signature, and then the X is, it's like a DNA, but I designed that, and then they designed. I told them what I wanted the imagery to look like. It just really came together very nicely. So, by the time this episode airs, pretty sure it probably should already be in preorders if it's not sold out. So, if you'd like to preorder the supplement, which really quickly is an enzyme originally created by the Japanese silkworm. You take it in the fasted state, it breaks down protein buildup, so it can help with inflammation and allergies and brain fog and it can reduce cholesterol, breakdown amyloid plaque, and fibroids, and pain relief, and all these things. The website for it, is avalonx.com, and the email list for all the information on it as well as future supplements, is melanieavalon.com/serrapeptase S-E-R-R-A-P-E-P-T-A-S-E. So that is that. 

Gin Stephens: Congratulations.  

Melanie Avalon: Thank you. It's actually releasing as of this recording date this week, most likely. Like a midnight release thing. So, we shall see. Anything else new with you? 

Gin Stephens: No. Not really. I stopped to finish recording my Audiobook. So, got that coming up. I'll be glad when it's over. I love all the people who love to listen. But Lord, it's hard. [laughs] It is really hard to read a book. Clean(ish) has a lot of hardness in it. A lot of difficulty.  

Melanie Avalon: Hard words.  

Gin Stephens: Yes. I'm like, “Why did I write that? Why? Why did I write that?” I will be talking to the director and I'm like, “Can I just change this?” She's like, “No, that's a direct quote out of a journal. You cannot.” I'm like, “Okay. But why did they write it like that?” Like, how to say things, it's so hard.  

Melanie Avalon: You know what I would be curious to hear? 

Gin Stephens: What? 

Melanie Avalon: I think Fast. Feast. Repeat. is on Blinkist.  

Gin Stephens: What is Blinkist?  

Melanie Avalon: It's this, I don't know-- it's a website. I keep hearing about it on [unintelligible [00:10:17]. But it's a website where they put 15-minute summaries of nonfiction books. So, you can like, learn a lot really fast. I think your book is on there. 

Gin Stephens: I feel it might be. I think someone might have told me that, that sounds familiar. I don't really know anything about it.  

Melanie Avalon: I was contemplating downloading it not to replace researching books for my show, because I always have to read everything. But just as a recap at the end, like a summary of the book. 

Gin Stephens: For Fast. Feast. Repeat? 

Melanie Avalon: No, just in general for prepping my other-- 

Gin Stephens: Oh, I see. Okay. I was like, “What? Why do you need to listen to Fast. Feast. Repeat.? Whatever. Okay. Yeah. 

Melanie Avalon: Like prepping other books. 

Gin Stephens: Well, that wouldn't be a bad idea.  

Melanie Avalon: I'd be curious if you listen to the Blinkist, did they put in what you would want to be the 15 minutes?  

Gin Stephens: Oh, I don't know. See, that's the kind of thing that would drive me crazy. So, I'll probably never listen. I don't want to know. That kind of stuff is so frustrating.  

Melanie Avalon: It's funny. All right. Shall we jump into everything for today?  

Gin Stephens: Yes. Let's get started.  

Melanie Avalon: All right. To start things off, we have some feedback. This is from-- Oh, no. We had this discussion recently. This is from, here we go, Andrea, Andréa, A-ndrea, And-rea, one of those. Andrea. She sent this email to me, but I asked her if we could include it because I thought it was a nice email. She said, “Hi, Melanie, I'm really fan crushing emailing you right now. I have not had a good enough question that felt worthy of emailing to the show. But I want to take this opportunity to thank you and Gin for all that you do. I'm a 44-year-old that found intermittent fasting after a long battle with my weight and anemia, that I later learned stemmed from methane based SIBO that developed after years without an appendix and gallbladder. While everyone understands how the gallbladder works. Did you know the appendix produces a probiotic that helps balance the microbiome? It's not so useless. after all.” I'd never heard that. Had you heard that, Gin. 

Gin Stephens: I haven't heard that. No, but I'm not surprised that it's not useless, because-- just because we don't understand what something is doing, doesn't mean it isn't doing something important. One of those things that never made sense to me. “Oh, you don't even need it. It's just there.” I'm like, “I doubt that.” [laughs]  

Melanie Avalon: I wonder if there is anything that as a species did become purposeless that we lost that we don't have now.  

Gin Stephens: I don't know.  

Melanie Avalon: Hmm, that's something to research. She says, “After resolving my gut issues with high dose herbs, biofilm disruptors, and antifungals, then healthy probiotics and prebiotics. I started intermittent fasting, and I've never felt better. I first started listening to the Intermittent Fasting Podcast and from there, discovered your podcast,” and she's talking about the Melanie Avalon Biohacking Podcast. She says, “Now I am into so many of the hacks, I'm sure my family thinks I'm nuts, lol. But they have no argument when the results so clearly speak for themselves. I appreciate all you do to bring light to sometimes little-known topics and speaking with the experts in an understandable way.” So, those are some great feedback from Andrea. For listeners, SIBO is small intestinal bacterial overgrowth, and it's a gut issue that a lot of people, especially with IBS often struggle with, and it can be difficult to address. So, it's nice to hear that she worked out her gut issues and that intermittent fasting is really helping with that.  

Gin Stephens: Yeah, I think so too. It also made me reflect by listening, she's a biohacker now listening to the Biohacking Podcast. I think it's just perfect the way we each are so different. Here we are together on the intermittent fasting podcast, but we each have our different strengths here. But our strengths here have spun off into completely 180 podcasts. I mean, your podcast and my podcast couldn't be more different.  

Melanie Avalon: You think so?  

Gin Stephens: Well, I mean, we both interview people, but we're not talking about biohacking on my podcast. It's making intermittent fasting a lifestyle on Intermittent Fasting Stories.  

Melanie Avalon: Yeah, it's personal stories.  

Gin Stephens: It's personal stories. It's day to day stuff. It's nitty gritty of a life.  

Melanie Avalon: Yeah, exactly. Mine is all the random tangent rabbit holes into all the biohacking.  

Gin Stephens: I just think that's interesting.  

Melanie Avalon: We create a lot of good content.  

Gin Stephens: Yeah, but it's so different.  

Melanie Avalon: I know. But then it comes together here on this show.  

Gin Stephens: Yep. Well, good. Thank you, Andrea.  

Melanie Avalon: Yes, thank you.  

Gin Stephens: All right. We have a question from Sally and the subject is: “Best type meal to eat when breaking fast.” “I'm hearing protein/good fat meal is best when you're breaking your fast. Wonder why I'm being told that, and is there any validity to it? What are your responses knowing that Melanie likes paleo, so that kind of goes hand in hand, but Gin enjoys some carbs, including grains and starchy veg. So, do you really care? You just eat what you want? Or, is it beneficial to do something more intentional? And should the big meal be first within your window? Or, would you recommend maybe eating a handful of nuts as a start? And then maybe an hour later, have your bigger meal while in your window? Thanks.”  

Melanie Avalon: All right. So, this is a great question from Sally. Something I'd like to clarify because people often say that to me, people think I don't eat carbs. I might eat more carbs than Gin every night.  

Gin Stephens: I don't know. I doubt it.  

Melanie Avalon: How many carbs do you think you eat?  

Gin Stephens: I mean, I don't count things. I just eat.  

Melanie Avalon: I eat pounds of fruit every night. So, there's a lot of carbs.  

Gin Stephens: Well, I do not eat pounds of anything.  

Melanie Avalon: So, I eat pounds of meat, pounds of cucumbers, and pounds of fruit.  

Gin Stephens: I just like eat a meal of food. I'm not eating individual ingredients, like separately. Last night, I ate a burger from local farmhouse burger, which is really good high-quality burger. I had grass-fed meat, I had a whole grain burger bun, I had really high-quality French fries. So, that's not my typical meal. I usually cook at home. But last night, I was just craving a burger, and we actually were talking about it. Did I talk about it on the podcast? We're recording two days back-to-back. So, did I mention that I wanted a good burger? I think I did.  

Melanie Avalon: You definitely did to me.  

Gin Stephens: I can't remember if I said it on the air. Well, anyway, spoiler alert, I had one. [laughs]  

Melanie Avalon: How was it?  

Gin Stephens: It was really good. It hit the spot. My body was craving that beef.  

Melanie Avalon: Awesome.  

Gin Stephens: It wasn't like pounds of anything, but it was a nice meal.  

Melanie Avalon: Yeah, I'm just trying to see how many carbs, it probably equals out to.  

Gin Stephens: Like what you're eating? 

Melanie Avalon: Yeah. 

Gin Stephens: I just don't think of food as macros. I just think of food like-- I am sensitive to the idea that my body doesn't clear fat as well. So, I shouldn't load up on the fat. But I'm still going to, like, if I'm having bread and butter, I'm going to put butter on there till it's delicious. Not like a slab just to go crazy, but it's really good. Bread and butter are good together. So, I eat the food that makes me satisfied, and that tastes really good. I add olive oil to my vegetables, so that they roast well. It's part of the cooking process kind of a thing. 

Melanie Avalon: Yeah, I'll have to look it up later, but it's definitely a lot of carbs in the form of fruit. But as for her question, so the answer we always say, it's very individual. You have to find what works for you. I think a lot of the concern about needing to be super specific and careful when you “break” your fast is, in general, likely more applicable when you're breaking a much longer fast. So, like an extended fast, because there's just idea of slowly reintroducing foods. 

Gin Stephens: Yeah. That is not every day what we're doing. I don't have to be careful at all. There are some people who have digestive upset even with a daily eating window. I mean there are. People have like a supersensitive system, and if they're not opening carefully, they experience dumping. We hear it a lot in the community. I didn't know if you had, but that really is something that happens to a small segment of the people, never happened to me.  

Melanie Avalon: Yeah, it doesn't happen to me either. But as far as to break it with, so I think a reason people say, like protein and fat is because that will likely fill you up fast, if you're trying to not overeat or get satiety signals soon. Protein is often the macronutrient that really leads to satiety. There's the whole protein leverage hypothesis, which says that we will eat to get our protein needs. So, we'll keep eating in any given meal or situation until we get our protein needs. So, that might be a reason somebody might want to start with the protein, because they'll fill up faster. But it really is a matter of just what digests for you, what you like.  

For me, I would not want to start with something like that because that would really slow down my digestion. I do do a specific ordering to my food, and it's because with that order, that I had found that works for me. I digest it well, none of the food compounds slow down the other compounds because I tend to lean towards digestive issues, so I do have to be careful. I would just experiment and find what makes you feel good.  

Gin Stephens: Nuts make me queasy on an empty stomach. So, I absolutely would not start with a handful of nuts. That would be the wrong thing for me. I talk about how a lot of things don't bother me. Well, tea makes me queasy on an empty stomach and nuts make me queasy on an empty stomach. I also don't think protein and good fats on their own would feel good to me. That would probably also make me queasy on an empty stomach. 

Melanie Avalon: Make you queasy? 

Gin Stephens: Yes. My stomach needs starchy carbs.  

Melanie Avalon: That's funny, that settles my stomach. If I ever have an upset stomach, if I just eat a big hunk of protein- 

Gin Stephens: Oh, God, no. 

Melanie Avalon: -that will always settle my stomach.  

Gin Stephens: Nope, nope, no, opposite. When I was sick last week and not really hungry, I couldn't even look at me. I didn't want me, I wasn't interested in me. I was like, “Chad, you're in charge of your own dinner. I just can't.” I cannot eat any meat. I did eat eggs. Eggs sounded good. But it wasn't a big piece of meat. Like scrambled eggs, I was eating like egg sandwiches, that sort of thing. So, I was still getting protein that way. But I absolutely did not think I could eat meat. Which is why when I suddenly felt better, I was like, now I need a cheeseburger. Isn’t that interesting? 

Melanie Avalon: That's so interesting. If I ever have an upset stomach, or if I'm ever sick, the thing I will crave is just pure animal protein. 

Gin Stephens: Oh, and a grilled cheese sandwich. I always crave a grilled cheese sandwich. Grilled cheese sandwich and apparently egg sandwiches.  

Melanie Avalon: Oh, yeah, we talked about that because I've never had an egg sandwich.  

Gin Stephens: So good. Scrambled eggs on bread. The whole moral of the story is, we're all very, very different with what makes you feel great. And you're just going to have to figure it out. The person who is telling you to eat a protein/good fat meal, probably that's what makes them feel the best. So, they're like, “Well, everyone should do that.” But that doesn't make it true. 

Melanie Avalon: I did have an experience though, like the different foods, if it has a big effect on you, you can really notice. For example, I, at my birthday dinner this past week, it was amazing. I was having wine and I had fish and mushrooms and everything was delicious, and I was feeling satiated. And then they brought out so many random things that most of them I didn't eat, but they did bring out this dessert plate. They told me what was gluten free and so there was a strawberry gummy bear thing. I was like, “It's my birthday. I'll just eat this.” So, I ate it. It was tiny. And it was so sweet, I ate it, after eating a full meal and then I was starving. It was such a good moment to experience just how much of an effect the foods can have. I went from being like completely full and fine, to starving from a tiny little gummy bear. 

Gin Stephens: That's so interesting. 

Melanie Avalon: Because it made my blood sugar drop. Reactive hypo, I'm guessing, or just like that craving from the sugar, like switching over to that mode.  

Gin Stephens: Today's episode is sponsored by Prep Dish. I want you to think through your day. What are the hectic daily moments you dread? For many of us, it's 5:00 PM when you realize the dinner hour has somehow snuck up on you again and you have no plan. Naturally, this is also the time young kiddos start losing it. Trying to throw together a healthy meal amidst that chaos is just plain hard. Even though my kids are grown, I remember those days well. Often, I would just hit the drive thru, again.  

Prep Dish is the best way for busy people to get healthy meals on the table without the stress. Subscribers receive an email every week with an organized grocery list and instructions for prepping meals ahead of time. This means dinnertime is super quick and easy every day. The best part, Prep Dish has weekly Super Fast Menus. This means, in addition to gluten free, paleo, and low carb or keto menus, subscribers now receive a new Super Fast Menu each and every week. These menus require only an hour to prep the week's food. And we're not talking boring pasta or plain chicken. Super Fast menus include items like shrimp tostadas, slow cooker sausage and kale soup and smothered mushroom chicken with mashed potatoes. The founder, Allison is offering listeners a free two-week trial to try it out. I mean, what's better than free? Nothing.  

Check out prepdish.com/ifpodcast for this amazing deal. Again, that's prepdish.com/ifpodcast for your first two weeks free. And now, back to the show.  

Melanie Avalon: Shall we move on to the next question?  

Gin Stephens: Yes.  

Melanie Avalon: So, this is a question from Paul. The subject is: “You guys.” Paul says, “How did you guys get to be so funny? [laughs] I don't think we're that funny. 

Gin Stephens: Well, I just realized that my zipper is down, so that's kind of funny. I'm fixing it now, sitting here with my zipper down.  

Melanie Avalon: You wear zippers? 

Gin Stephens: I'm wearing jeans. I wear jeans all the time.  

Melanie Avalon: I don't remember the last time I had a zipper, that was not addressed. He says, “Truth is, you brighten my day with your always upbeat conversation. Will you ever take your show on the road for some live tapings? And, of course, will you start with Boston?” Doubtful. 

Gin Stephens: That does sound fun, though, but we first have to meet.  

Melanie Avalon: Yes. 

Gin Stephens: Atlanta is where we'll start.  

Melanie Avalon: So, this is just a little fun fact into podcasting. The setup for recording in the same room is drastically different from the setup-- 

Gin Stephens: That is true.  

Melanie Avalon: Yeah, for the setup, like right now, it would be a completely different setup.  

Gin Stephens: It's harder. When I was at the beach in August, I had to record two episodes of people live. And they were just not as good. I recorded one with my friend Michelle, she's amazing. I don't regret that we did that. I love that we did that. But sounds are different and trying to share the same microphone.  

Melanie Avalon: Did you share microphone?  

Gin Stephens: We did. I was just listening-- You sent me a podcast yesterday, I'm not going to say who it was, but I listened to it. And I noticed they had wacky quality of sound. 

Melanie Avalon: On both sides? 

Gin Stephens: Well, the host, the main guy, the one whose podcast it was. There was a beginning part and that part was really professional sound quality. And then the part where he was interviewing his guest, it sounded like he was like in his car or something, I don't know. Or maybe on his phone, it sounded like maybe he was on his phone, but I just thought that was interesting. So, I don't get real stressed out. The point of my story is, not to criticize someone else's podcast, but that it makes me feel better because I know that sometimes if I have a guest, the audio is not perfect, and I don't let that stress me out. That's my point.  

I was listening to this amazing podcast or who had great content, and I really enjoyed it. And thank you for sending it to me. I just noted that the audio wasn't amazing, and I didn't judge it. But it made me feel better about myself. That was why I told that story. [laughs] Anyway, it might not be perfect, but it's-- actually my director told me that when we were recording the Audiobook. She's like, “Podcasts can be recorded on the street, but for Audiobook, it has to be perfect.”  

Melanie Avalon: Yeah. It's interesting. I have had a few requests on my other show to do it live. So, I remember when-- I haven't released this episode yet, but I did an episode on hyperbaric chambers. And I'm like friends adjacent with the guy, like he's a friend of a friend. He was like, “You should come down to my hyperbarics and we’ll record from the chamber.” I was like, “No.” [laughs] He was trying to convince me to do that for a month.  

Gin Stephens: Seriously, though, it doesn't have to be perfect. Just have some fun.  

Melanie Avalon: Well, so here's the other thing. And then I had Brad Kearns on recently, and we've become really good friends. And he's like, “We're going to do another one. We're going to do it live.” And I'm like, “No, no, no,” because here's the thing, with my other show, well, it might be different if it was more casual, like talking again with Brad. But, in general, I have so much prep work that, I need my notes, I need to not have the camera because they need to be like-- basically, I like have to be in my zone, as the way I perceive myself as a performer. If I was in real life with these guests, it would add a whole another aspect of me being aware of like what I look like. 

Gin Stephens: 100%, I get that, yep. People have been like, “Why don't you do a video of your podcast too, and then you could put it on YouTube, because so many people do.” Because I don't want to. I don't want to be on video while I'm recording with someone. I take notes while we're talking, I take notes what my guest is saying, and then I circle back to things, but I'm writing and I don't want to have to think about how my face looks. And do I look weird? Yeah, I get it.  

Melanie Avalon: Do you do video?  

Gin Stephens: Well, we can see each other while we're recording, yes.  

Melanie Avalon: Okay, but you don't want to air it. 

Gin Stephens: But we don't record it. We don't record the video. No, no, I've no desire to record that and air it. 

Melanie Avalon: Me, too. I'm that plus one step more. I don't even let the other guests see me because it would just take me out. I have so much going on in my head when I'm doing those shows. I can't-- It would really stress me out, too bad.  

Gin Stephens: I enjoy being able to see the person we like, we see each other. That's okay. Sometimes if we have weird internet, we'll have to turn off the video and I don't like it as much. I like to be able to see the person I'm talking to, but I don't want the world, I don't want to have to worry about it, because when I'm being recorded, sometimes someone will record me for a podcast and it'll be video and it just feels-- it feels like I have to be like on in a different way that I don't want to be. It's a different thing to think about.  

Melanie Avalon: I feel like most of the shows I go on, I don't seek out going on other podcasts, but if people invite me- 

Gin Stephens: Ditto, yeah. 

Melanie Avalon: -which is a good problem to have, because I know a lot of people would die to be on some of the shows I've been on, but most of them are video. And it is-- it is a completely different experience, but it's easier for me on video if I'm the one being interviewed because then I'm not-- I'm just answering the questions. 

Gin Stephens: That's true. Yeah.  

Melanie Avalon: The one I did this week-- did I mention it on the show that I did one with Bill Tancer, New York Times bestselling author, but he's going to come on my show.  

Gin Stephens: I know you told me. I can't remember if you said it on the show.  

Melanie Avalon: It's funny. I could tell, especially interviewing with him, we were very similar. We were talking about this, we see the world kind in the same way and he understood right from the beginning, I told him, I didn't really want to do video if that was an option. He totally understood. So, I do appreciate that. I mean, obviously, my dream is still to have a talk show and that would be completely video. But that would be different.  

Gin Stephens: I wouldn't mind doing a Clean(ish) television show. Wouldn't that be fun?  

Melanie Avalon: I know. 

Gin Stephens: Like Marie Kondo came in and help people say goodbye to their things. I could go in and help people get Clean(ish) in their bathroom or in their makeup or their pantry.  

Melanie Avalon: Maybe I could produce your show.  

Gin Stephens: That would be fun. I think I would have fun with that because it's just me and regular people and here we are, and let me help you with this, and look at this product, can you believe it?  

Melanie Avalon: Yeah. 

Gin Stephens: I would do that. That would be fun. I love people. I love hanging out with people and talking to people and doing stuff with people.  

Melanie Avalon: Yeah, this is why I want like a talk show. I like people in a controlled setting, so I would want everything to be very controlled. 

Gin Stephens: I'm the opposite. I'm like, “Let's just see what happens.”  

Melanie Avalon: I want studio audience, I want the lineup, everything is very much on point. [laughs]  

Gin Stephens: The people have the card that says 'applause' and everybody would applaud. 

Melanie Avalon: More so just the outline of where it's going to go in the segments, and we're going to do this at this point. And, yeah, I'll let the audience person handle the audience, but I would die to have a show with an audience. That would be so amazing because it would be doing the shows that we do now, but then I will get to interact in real time with people reacting to this stuff. Ah, it'd be so fun. Goals. 

Gin Stephens: Yeah. Well, Paul, thank you so much. I'm glad you think we're funny. Yeah, we get to do this for a job. That is so-- I can't believe it. 

Melanie Avalon: I'm super grateful.  

Gin Stephens: Me, too. I really love it.  

Melanie Avalon: Me, too. I really do. Now we have a question from Phoebe. The subject is: “IF and Weight Gain.” Phoebe says, “Hi, I first want to say how informative your podcast is. There is so much “bad science” out there. And I think it's great you're both espousing, so much reliable knowledge to your listeners. So, thank you for that. I started IF about two weeks ago, I found 16 hours tough in the beginning, but now I can get to 19 to 20 hours before wanting to eat again. I've been doing HIIT or strength training with small weights for about an hour each day. I feel great during the fast and I love waking up with a flat stomach. I had no issues switching over to clean fasting within the first week and only have black coffee and water in the day. My issue is I have not lost any weight, and instead I keep fluctuating around the same mark. Some days I eat more, and others less, I only really ever seem to go down on the scale if I drink wine the night before, but I don't know if that's due to dehydration. 

I'm 5’7” and 24 years old, but I've gained about 20 pounds about 10 during quarantine that I'm desperate to lose. I'm sensitive to dairy and I have digestion issues when I eat high fiber foods such as rye bread and bananas and also cruciferous vegetables. I can eat in very small doses and be fine, but too much, and I get stomach pains/gas/bloating. I don't know if I haven't given it enough time or if maybe I'm eating too much in these meals and I should calorie count. I really want IF to work and I'm sad at the lack of my own progress. I know, Gin, you say that I might be getting smaller/building muscle, but all of my jeans still tight. Do you think it's something to do with cortisol levels or water retention?” 

Gin Stephens: No. 

Melanie Avalon: [laughs] I know--I know Gin has been like dying this whole time. 

Gin Stephens: No. I do not. I do not think that’s it, Phoebe. Sorry. [gasping] Go ahead, keep going.  

Melanie Avalon: One more sentence-- One more sentence Gin. 

Gin Stephens: It's none of that, Phoebe. All right, go ahead.  

Melanie Avalon: “Would love your advice on the issue. Sorry for the giant mega essay. Phoebe.”  

Gin Stephens: I highlighted three words. 

Melanie Avalon: Can I guess what they are?  

Gin Stephens: Yep. 

Melanie Avalon: Two weeks ago. 

Gin Stephens: Yep. Those are the three-- those are the three words I highlighted. That's all you need to know, Phoebe. You just started two weeks ago, there's no diet plan of the world that is going to cause you to lose amazing amounts of fat quickly. You might go down really fast on the scale and certain diets you've done in the past, but we don't lose fat that quickly. But with intermittent fasting, we definitely do not lose weight quickly. It sounds to me you probably have not read Fast. Feast. Repeat. I would really recommend that you read that. Anyone who's starting out, is not just because I want to sell you a book, I promise. It's because I think it's valuable. If I just wanted to sell people book, Delay, Don't Deny, I could have just kept selling that one. I wrote Fast. Feast. Repeat. because I wanted a better book out there. I'm really proud of Fast. Feast. Repeat.  

I would recommend, if you're starting out, take the time to listen to Fast. Feast. Repeat. if you don't like to read, it's on Audible, I read it to you. I want you to start with the 28-Day Fast Start chapter. In that chapter, I'm very, very, very clear that you should not expect weight loss in the first 28 days. That's because your body is learning how to do something new. You're learning how to tap into your fat stores for fuel. So, you're like fasting during the day, then you're also working out in there, and then you're eating, and then your body's doing all these changes. A lot of things are going on behind the scenes. But what your body is probably not doing great yet, is burning fat and metabolically flexible, and all the magic that we want to have happen. So, I don't think that it's that you're building all this muscle and you've lost all this fat. I mean, it's only been two weeks.  

I also want to encourage you to read the Scale-Schmale chapter, that is a very, very, very important chapter. It talks about all the different ways that I want you to measure your progress. The scale is a tiny little piece of that, especially since you're doing high intensity interval training or strength training for an hour every day. That is going to lead to muscle building. I'm not saying that's what's happened already, because it's only been two weeks. But you are going to probably see body re-composition with the combination of fat burning once your body is adjusted. And then now you're doing this high intensity interval training and strength training, so you're going to be building muscle well. You're going to need to use a lot of different tools to measure your progress, and the scale is likely to be the least effective. Especially since you only have 20 pounds to lose, and you're young, you're 24 years old. So, you're probably going to be better at building muscle than someone who's my age.  

You're going to need to use things like progress photos, honesty pants, measurements. If you just are desperately staring at the scale, you're going to be really, really disappointed because you will probably find that you get down to your dream body, and you probably aren't going to see the actual number on the scale you think you need to see, because your body is going to change so much. But it's way too early to be stressing about that for now. You got to give it a long time. It might take you 20 weeks to get to your dream body. Like I said, it might not even be the number on the scale that you think it's going to be ever. You got to let go of that that number and instead focus on what your body does. And your clothes, your measurements, your progress photos, that is really the best way to judge it.  

I don't want you to be all worried about, “Oh, my gosh, I got to change everything because this isn't working.” Your body's doing what it's supposed to do. Just keep going. And don't be sad, because again, two weeks is not very long in the whole scheme of things.  

Melanie Avalon: I really have nothing to add to that, I think. [laughs] Our next question is actually similar about as far as like weight loss. So maybe we can see if there's any nuance to be added for Ashley's question. But, yes, hopefully, Phoebe, feel free to write back and report back if you are still having issues way down the road. 

Gin Stephens: Yeah, because that's really important. You really have to give it the long-term approach. And even if you are using the scale, it can be an important tool, but you still have to focus on your overall trend. I talk about and Fast. Feast. Repeat. why it's important to weigh daily if you're using the scale, and calculate your overall trend. There are apps that do that for you, like Happy Scale. I like to do an old school because that's just me. I wrote it on paper, got out my calculator, added it off, divided by seven. I even put it on a little graph by hand. There was just something pleasing and plotting it, that made me feel like, “Here I am. I'm plotting it on my graph.” Knowing the overall trend is really important. 

We have a question from Ashley, and the subject is: “Windows, Endurance, Sports, Leaning Out.” All right. She said, “First off, let me say that I love you ladies and feel like we are friends. I've never been into podcasts until I found you. My dad actually said, ‘You need to listen. They are like you.’” Oh, I love that your dad said that. I mean, your dad is listening. Hi, dad or Ashley’s dad. All right. She said, “And I've been hooked ever since. I'm an elementary school counselor and have been following a paleo/primal diet for seven to eight years. I began IF 16:8, not really knowing what it was, and only stopped for pregnancy with my twins. I had to eat to help my morning sickness. I just completed two marathons and run half marathons about four to five times a year. In addition, I teach group fitness class with high intensity interval training, weights, and cardio two to three times a week.” I still have hard time just saying HIIT. I think they say HIIT, right? 

Melanie Avalon: Yeah. I always say H-I-I-T.  

Gin Stephens: She said, “Sorry for all the info, but I feel like it's helpful to have the background.” Yes, Ashley. We like the info, so thank you.” She said, “I currently alternate between a 16 to 24-hour window. I play around with what works for that day, with Sundays very relaxed. Here's my question. I'm looking for fat loss. Do I keep my window more consistent and pass the 18-hour or 20-hour mark always? Do I forego my paleo treats in my window? Do I focus on carbs? Please help and keep up the good work. Thanks so much, and keep on keeping on. Much love.”  

Melanie Avalon: Did she say how long she's been doing IF? 

Gin Stephens: Ah-huh. See, that's the thing. So, I have no idea.  

Melanie Avalon: I vote that we approach this like she's been doing it longer.  

Gin Stephens: Well, it sounds like she did it and then she got pregnant and stopped doing it. And then she started doing it again.  

Melanie Avalon: If it's the situation where she hasn't been doing it long, then she can apply the Phoebe answer. 

Gin Stephens: True.  

Melanie Avalon: We can answer this now for if it has been longer. First, I want to comment though, on the morning sickness. I have not aired the episode yet. I'm not sure when it's airing. But I interviewed Dr. Michael Platt. And he wrote a book called The Miracle of Bio-Identical Hormones. And he talks a lot about morning sickness and makes a huge case for supplemental progesterone to resolve that. I don't have any experience with morning sickness and pregnancy and progesterone. So, I can't speak to it personally. But for any listeners that are pregnant and experiencing that, that might be something to try. And I've been using this cream every night. I've been using progesterone for years. But I switched over to his cream and saw a huge, huge benefit. And then on top of that, my sister, I don't know, I might have shared this on the show already. But my sister had PMDD, which is basically the really intense diagnoseable form of PMS. And she's had it for like a decade, and she's tried so many things. She started taking the progesterone cream. And he says in his book, and I'm sorry, this is a tangent. He says in his book that it'll just go away.  

I told her about it, and she started taking it, and it just went away after 10 years. She was shocked. I was so happy. I was like he really makes it sound like this will resolve it and she's been dealing with this for so long. So, I will put a link in the show notes. I do have a discount code. Michael Platt is the brand. I think the code is MELANIEAVALON for discount. But that's just a resource for morning sickness. But back to the question. Ashley is doing a lot of activity. Just want to note that. Okay. Assuming you have weight to lose, because she doesn't-- 

Gin Stephens: Yeah, she sounds like she's trying to lose fat and she's maybe having trouble with that. 

Melanie Avalon: Yeah. The important things to focus on is the diet that provides the nutrition that you need, especially when you're doing all of this exercise. All of the protein, all the nutrients, but is ultimately two things. One, supporting the fat burning state. Of course, with intermittent fasting, the fasting is creating that, but you can really tweak that even more by finding the dietary macros that your body burns very efficiently and lets you really go into the fastest state with no hunger and continue the fat burning mode. And then also, if it's-- fat loss is the goal, focusing on foods that really fill you up without adding a huge surplus of calories because a lot of people think, “Oh, I'm fasting, so it doesn't matter.” I'm not saying that you think this actually, but a lot of people might think that they're fasting, so it doesn't really matter the calories that they're eating. Again, we're not about counting calories. We already said we don't count calories. But choosing the type of foods that are not going to necessarily create a massive calorie surplus, especially calories that are easily stored can definitely have a huge effect on weight loss.  

Gin Stephens: Like what are paleo treats? She said, does she need to forego paleo treats. I don't know what that might even be because I've never tried to do paleo.  

Melanie Avalon: I don't know what that is. But a lot of paleo treats are often things like, nut butters and lots of nuts. 

Gin Stephens: Like very nutrient dense, but also calorically dense. 

Melanie Avalon: So in my book for example-- I'm just thinking about the recipes in my book. I have recipes for brownies made from avocado, like avocado brownies and cakes or things like that made from almond flours instead of normal flour. I do find that the-- It depends where they are, but the paleo treats can often be pretty high calorie. So, the point of all of that is, you can eat too many calories in your eating window, so that you don't lose fat in your fasting window. So, you can really choose where you want to focus and try different things because she also asked about, “Do I focus on carbs?” So, I do think if fat loss is the goal, looking at macros, to find the macros that work for you and experimenting is a really good way to go. Maybe low carb works for you. Maybe low fat works better. Maybe one works at one time, maybe one works at another time. But if trying a low version of either one, so either low carb or low fat can often work really well. If you are having those paleo treats, cutting those out can help really well. Ashley might not be eating this. It might not be in her “paleo protocol.” But just for people in general. If they're eating massive amounts of things like cheese.  

Especially after-- I already thought this already, but especially after reading Dr. Neal Barnard’s book, The Cheese Trap. I don't agree with everything that he says, but he does make a very big case for just how incredibly fattening cheese is. If you're eating massive amount, even, maybe not even massive amounts, but a lot of cheese in your window, that could really be stalling weight loss. I think nuts can often stall weight loss. But then also, she asks about like, does she need to actually change the window? Does it need to be consistent? Does it always need to be longer? What I would probably do, and I feel like I'm all over the place right now is, I would probably first find the window that you're liking, if a consistent window does work for you, and then if that's not working, I would tweak with the food choices. And I would really just go in the order of what feels right to you. So maybe it's trying to just cut out these treats, or maybe it's working on the macros. But, yes, things can be done. Oh, and focusing on protein. 

Gin Stephens: I would also be very cautious. If you're really, really doing a lot of physical activity, teaching group fitness classes, two to three times a week. I mean, you probably need a longer eating window, you need to fuel your body because we talk about how intermittent fasting is not a problem for women, but over restriction is. And if you're really hitting the gym hard, and restricting your diet, and intermittent fasting and pushing it more and more, that does turn into a state of over restriction. So, you just have to kind of find the balance, so that it isn't overly restrictive for your body. I just think that's really important. We've gotten to the point in society where we're like, “Well, let's just do more. Let's do more high intensity training. Let's have a longer fast.” Really, maybe you just need to, you did say Sundays are very relaxed, that's good. But that doesn't mean you need to just keep pushing it more every day necessarily, but I feel you already know, Ashley, because when you said, “Do I forego my paleo treats in my window?” I think that was you kind of knowing that might be it. 

There're some things that are really easy to eat. It might be something that's like perfectly on plan, but that doesn't mean that it's helping you with your fat loss goals. 

Melanie Avalon: This is just me personally. The thing I love about fasting and the eating window is, I don't ever want to restrict the quantity of the food I'm eating. I don't want to ever have to feel like I have to stop eating, and I'm not saying anybody has to do that. But when I focus on just whole foods, so I don't make these paleo treats. I don't eat nuts. I have been eating actually fat free cheese recently, I've been experimenting with that, but don't do high fat cheese or anything like that. If I eat the certain foods that I eat that are all whole foods, I really can just eat as much as I want it. It's going to support for me either like maintenance or weight loss. It doesn't really lead to weight gain. Whereas if I added in, at least for me personally, things like this, it could be made from the same substrates of “paleo foods,” but when they enter this more process form, it's a way to eat a lot of more processed calories really fast, and I might not be able to just eat unlimited amounts of that. So, yes. 

Gin Stephens: All right. That was a lot, but I felt like it was good.  

Melanie Avalon: Hi, friends. Winter aka sick season is upon us. And we all know that this is the time of year to take extra care to protect ourselves from germs and bacteria. Of course, you can do everything right, wash your hands, keep your hands away from your face, carry around some hand sanitizer, but you still get sick. That's why you need to protect your body from the inside, not just the out. And you can do that by building up your immune system with some high quality and high strength probiotics. That's why I'm really excited about P3-OM is a patented probiotic that might be the most effective probiotic ever developed.  

P3-OM fights bacteria and strengthens immunity. It's basically a germ fighting superhero. But it also helps digestion, speeds up metabolism and increases energy throughout the day, which is way more than you might have thought probiotics could do. And just when I thought P3-OM couldn't get any more powerful, I watched a video which you can see at p3om.com/ifpodcast of the probiotic literally breaking down a piece of steak. After I saw that, I was all in. You guys are going to be so amazed, too. Definitely check out that video. And here's some more awesome news.  

You can get 10% off P3-OM right now by going to p3om.com/ifpodcast and typing in the coupon code IFPODCAST10. And here's the thing, if you order it, and it's not everything you hoped for, BiOptimizers support team will give you all of your money back, no questions asked. So, if you want to protect yourself from whatever bug is floating around this year, and take your digestion to a new level, visit p3om.com/ifpodcast, to get a 10% discount with the coupon code IFPODCAST10. And we'll put all this information in the show notes. All right, now back to the show.  

All right. So, now we have a question from Jennifer. The subject is: “Feeling Full.” Jennifer says, “Hi, Melanie and Gin. I love your podcast. A friend of mine suggested IF and she suggested that I tune in.” This is the second question where it was suggested by somebody. 

Gin Stephens: I know, I love that. 

Melanie Avalon: She says, “I'm so glad I did. I spent years yo-yo dieting and it was awful. I've been following 16:8 and I'm about a week in. I feel great already. I've been told for years by my doctor and herbalist that I'm insulin resistant, but I didn't want to accept that. I finally have the mindset that it's time to take control and feel better. Here's my question. I have noticed that during my eating window, I get very full very quickly. I've stopped eating and found myself super hungry during the fasting period. I clean fast. I don't want to force myself to keep eating during my eating window either when I feel so full. Suggestions, I want to get my nutrients in, but I don't want to overdo it. I'm eating very little carbs.  

Gin Stephens: All right so Jennifer, I'm going to give you the same advice I gave a few questions ago. And that is that you are still so very new. You are, what, one week in? You're not at the point yet where you're really tuned in to what's happening in your body. The whole idea of appetite correction, that's a term coined by Dr. Bert Herring. I talk about it in Fast. Feast. Repeat. So, if you've got Fast. Feast. Repeat., go to that chapter about appetite correction and read about it. I love the concept. Basically, the idea is that our bodies are born to know when we've had enough to eat so that we stop eating. All the animals in nature, they eat, they stop eating. You don't see obese lions out there. We only see that when animals are like human fed. We start feeding them the things they're not supposed to eat. We start feeding the ducks the bread and now the ducks are having problems. But as long as we leave the animals alone, they know what to eat and how much to eat without even counting a calorie. They just stop.  

The thing about intermittent fasting is, once your body adjusts, and you're tapping into your fat stores during the fast and you're feeding your body nutritious foods, during your eating window, you can reconnect with those natural hunger and satiety cues that your body has. It doesn't really help that you're eating real food though, because just like those ducks that overeat the bread because they're not really supposed to be eating that bread, but we're feeding it to them and they just keep eating it. Same with us. If we're not eating enough nutrients, then we're not going to hear that we've had enough to eat. But my point is that, your signals are all out of whack because you're still early on. So, give it some time. You’re going to be hungrier during the fast now in the early days, then you will after a body adjusts. So, just be patient with your body. Read the chapter again, like I said, on appetite correction.  

No, you do not want to force yourself to keep eating if you feel full. That is 100% true. But if you're really, really starving during your fast, that could just be the adjustment period and that's going to get better as you go.  

Melanie Avalon: That's such a good reframe. She was obviously thinking that the hunger was from the not eating enough, but it might just be the lack of adaptions. So, let's say she's down the road, and she's been doing IF for a few months, like it for anybody who had been down the road, and are still experiencing hunger. And if it is from not eating enough, what do you recommend in those situations?  

Gin Stephens: Well, I mean, that usually doesn't happen. Especially when she's got an eight-hour window, I would have a really hard time with the idea that she couldn't figure out how to eat enough food in an eight-hour window. You could put two meals in there and it works its way out usually after you're adjusted. This is not something that usually keeps coming up after someone's adjusted.  

Melanie Avalon: Okay, perfect. I think you answered that.  

Gin Stephens: All right.  

Melanie Avalon: So, we have one last question from Carla. The subject is: “Hormones.” Carla says, “I have heard that IF will help regulate--” She says she's not sure what the exact word is, but your hormones. “How long does this typically take? And how can you tell it is working? When I asked this question to an IF Facebook group, they couldn't answer it, and they just asked if I have insulin resistance? I have no clue. How do I know if I have insulin resistance? I'm so confused.” 

Gin Stephens: Well, this is a very broad question like, “Will IF help regulate your hormones?” The answer is maybe yes, maybe no, depends. It depends on which hormones. Now I totally understand why they asked if you have insulin resistance, because that is one hormone that intermittent fasting will help you regulate your insulin levels. When they asked you, “Do you have insulin resistance?” That was them saying, “Well, if the answer is yes, you have insulin resistance, then yes, intermittent fasting will help regulate that.”  

Hormones are such a broad topic in your body, you've got a lot of different hormones. You've got thyroid hormones, you've got metabolic hormones, you've got so many different-- female hormones. 

Melanie Avalon: Even vitamin D is a hormone. 

Gin Stephens: Right, we can't tell you how intermittent fasting is going to impact all those many things that are going on in your body because it's like a balancing act. One thing that happens over here and that changes something that's happening over there. Intermittent fasting does help get a lot of those things into balance, but it just really depends on what your underlying conditions are. We can't really say this is what IF is going to do because we can't know. It just depends on so many individual factors. So, if you don't know if you have insulin resistance, then maybe you don't. But if you're overweight, if you've been struggling with your weight for a while, you probably do. And if the answer is yes, you've been struggling with your weight for a while, then probably yes, intermittent fasting is going to help with that aspect hormonally, and help with your insulin resistance.  

Melanie Avalon: I think as far as-- Gin said it really well. Hormones, it is such a broad term. I think we do throw it around pretty casually a lot. I already earlier was talking about hormones with-- I mean, progesterone, and that whole world, that's all hormones. I think a reason that IF does in general-- help hormones in general is that a lot of the hormonal dysregulation today often does come from our diet. The foods that we're eating, eating constantly can encourage a lot of hormonal dysregulation. And so having this fasted period, it can regulate in a way or potentially help certain hormones, definitely on the insulin resistance front. That's this very specific area of hormones that's dealing specifically with insulin, which is a hormone that's involved with your fuel use and fuel storage.  

In the dietary aspect of hormones, it's most likely going to really help with that. But then beyond that, all the other hormones, the female hormones, I think in general it tends to help a lot of people, but it really depends on what is your personal hormonal issue as to how it's going to affect that or what it's going to do. So, it's a very broad question. You could work with a knowledgeable practitioner, though, if you wanted to check on some hormones, actually some different resources.  

For example, if you listen to the ad on today's show by InsideTracker, they test for example, some hormones. Not a ton of them, but I think they test. They look at certain blood markers that correlate to metabolic health and longevity. They test the test that they think you need to be testing to really get a picture of your metabolic health. So, they test DHEA, testosterone, and sex hormone binding globulin because they feel like those are the most important hormones to be testing for metabolic health. So, you could check out their panel if you'd like to look into that. And then beyond that, you could work with a physician who could do other hormonal tests, you could do a DUTCH test if you want to look at hormones specifically related to women and estrogen and estradiol. And that is something that you need to look at on a 24-hour. I think it's 24-hours that you do the test and it's a urine test. Insulin would be something that you could test, doctors don't test it that much, but you can ask for it. Your HOMA-IR would be testing your insulin and comparing it to your-- I think your blood glucose and that can give you a good marker of insulin resistance or insulin sensitivity. So, it's a whole world. I encourage you to work with somebody on it. But in general, I do think a lot of people experience hormonal benefits with fasting.  

Gin Stephens: Yep, absolutely. The thing that's so important for people to understand is, intermittent fasting is an amazing tool for help. But it's not the only tool and it doesn't fix everything.  

Melanie Avalon: Exactly.  

Gin Stephens: It also doesn't cause every problem that you might have. It isn't the cause of everything or the effect of everything or the fix of everything. It's a tool that's really useful, it will always be in my toolbox. But sometimes I need a different tool for a job. I got a hammer in there, but sometimes I need a screwdriver.  

Melanie Avalon: Yes, exactly. I really think that phrase, “When you have a hammer, everything looks like a nail,” is a really enlightening phrase, because so many people think when they're looking through a certain lens, they might think everything is one thing, so that fasting will fix everything or that all the problems are from fasting. But there's so much more beyond that.  

Gin Stephens: Exactly.  

Melanie Avalon: Alrighty. Well, this has been absolutely wonderful. A few things for listeners before we go. If you would like to submit your own questions for the show, you can directly email questions@ifpodcast.com. Or you can go ifpodcast.com and you can submit questions there. The show notes for today's episode will be at ifpodcast.com/episode242. The show notes will have a full transcript as well as links to everything that we've talked about. And then you can also follow us on Instagram. I am @MelanieAvalon, and Gin is @GinStephens. Gin, I tagged you today in a photo, did you see that?  

Gin Stephens: Oh, okay. No, I didn't.  

Melanie Avalon: It's the flowers you sent from my birthday.  

Gin Stephens: Oh, I'll have to look. Well, good. I'm just not really on Instagram a lot. So, I'm trying to still decide. But I will definitely look and see the flowers. I'm looking right now. Oh, there they are. Oh, it looks all fancy.  

Melanie Avalon: See how they bloomed?  

Gin Stephens: Yeah.  

Melanie Avalon: Do you see how they're huge? 

Gin Stephens: They are huge.  

Melanie Avalon: Because when I first sent you the picture, and I should have taken it so that it wasn't all the green ones because there's a lot of pink ones on the other side. When I first sent you the picture, they were closed up. Oh, by the way, random side note. You know how I told you my cucumbers died and I had to start over? 

Gin Stephens: Yes.  

Melanie Avalon: Now they're growing again up the windows and today is the first day that a flower, like a massive flower. After this, I got to go pollinate them with my pollinator. Oh, man. I'm excited. 

Gin Stephens: Well, have fun.  

Melanie Avalon: I will and you have fun.  

Gin Stephens: All right, I will. 

Melanie Avalon: Actually, I guess, I'll talk to you after Thanksgiving, right?  

Gin Stephens: Yeah. That's when we're recording next.  

Melanie Avalon: So, have a fabulous Thanksgiving.  

Gin Stephens: You too.  

Melanie Avalon: All right. Bye.  

Gin Stephens: Bye.  

Melanie Avalon: Thank you so much for listening to The Intermittent Fasting Podcast. Please remember that everything discussed on the show is not medical advice. We're not doctors. You can also check out our other podcast, Intermittent Fasting Stories, and the Melanie Avalon Biohacking Podcast. Theme music was composed by Leland Cox. See you next week. 

STUFF WE LIKE

Check out the Stuff We Like page for links to any of the books/supplements/products etc. mentioned on the podcast that we like!

More on Gin: GinStephens.com

Theme Music Composed By Leland Cox: LelandCox.com

If you enjoyed this episode, please consider leaving us a review in iTunes - it helps more than you know!